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  1. interpro_active_site/advanced/idx2term.json +1 -0
  2. interpro_active_site/basic/idx2term.json +1 -0
  3. interpro_active_site/basic/plot_0.png +3 -0
  4. interpro_active_site/basic/plot_1.png +3 -0
  5. interpro_active_site/consensus.joblib +3 -0
  6. interpro_active_site/df_merge.tsv +1 -0
  7. interpro_active_site/metrics.json +7 -0
  8. interpro_active_site/paths.json +1 -0
  9. interpro_active_site/result.tsv +11 -0
  10. interpro_active_site/selections.json +1 -0
  11. interpro_binding_site/advanced/idx2term.json +1 -0
  12. interpro_binding_site/advanced/plot_0.png +3 -0
  13. interpro_binding_site/basic/idx2term.json +1 -0
  14. interpro_binding_site/basic/plot_0.png +3 -0
  15. interpro_binding_site/basic/plot_1.png +3 -0
  16. interpro_binding_site/consensus.joblib +3 -0
  17. interpro_binding_site/df_merge.tsv +2 -0
  18. interpro_binding_site/metrics.json +7 -0
  19. interpro_binding_site/paths.json +1 -0
  20. interpro_binding_site/result.tsv +7 -0
  21. interpro_binding_site/selections.json +1 -0
  22. interpro_conserved_site/advanced/idx2term.json +1 -0
  23. interpro_conserved_site/advanced/plot_0.png +3 -0
  24. interpro_conserved_site/advanced/plot_1.png +3 -0
  25. interpro_conserved_site/advanced/plot_2.png +3 -0
  26. interpro_conserved_site/advanced/plot_3.png +3 -0
  27. interpro_conserved_site/advanced/plot_4.png +3 -0
  28. interpro_conserved_site/basic/idx2term.json +1 -0
  29. interpro_conserved_site/basic/plot_0.png +3 -0
  30. interpro_conserved_site/basic/plot_1.png +3 -0
  31. interpro_conserved_site/basic/plot_10.png +3 -0
  32. interpro_conserved_site/basic/plot_2.png +3 -0
  33. interpro_conserved_site/basic/plot_3.png +3 -0
  34. interpro_conserved_site/basic/plot_4.png +3 -0
  35. interpro_conserved_site/basic/plot_5.png +3 -0
  36. interpro_conserved_site/basic/plot_6.png +3 -0
  37. interpro_conserved_site/basic/plot_7.png +3 -0
  38. interpro_conserved_site/basic/plot_8.png +3 -0
  39. interpro_conserved_site/basic/plot_9.png +3 -0
  40. interpro_conserved_site/consensus.joblib +3 -0
  41. interpro_conserved_site/df_merge.tsv +7 -0
  42. interpro_conserved_site/metrics.json +7 -0
  43. interpro_conserved_site/paths.json +1 -0
  44. interpro_conserved_site/result.tsv +59 -0
  45. interpro_conserved_site/selections.json +1 -0
  46. interpro_domain/advanced/idx2term.json +1 -0
  47. interpro_domain/advanced/plot_0.png +3 -0
  48. interpro_domain/advanced/plot_1.png +3 -0
  49. interpro_domain/advanced/plot_2.png +3 -0
  50. interpro_domain/advanced/plot_3.png +3 -0
interpro_active_site/advanced/idx2term.json ADDED
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interpro_active_site/basic/idx2term.json ADDED
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+ {"0": "Serine/threonine-protein kinase, active site [IPR008271]", "1": "Ubiquitin-conjugating enzyme, active site [IPR023313]"}
interpro_active_site/basic/plot_0.png ADDED

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interpro_active_site/df_merge.tsv ADDED
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+ term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500
interpro_active_site/metrics.json ADDED
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+ {
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+ "type_of_task": "ranksum",
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+ "signature_size": 3630,
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+ "annotations_size": 57,
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+ "title": "Average number of proteins per term",
6
+ "value": 2.789473684210526
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+ }
interpro_active_site/paths.json ADDED
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+ {"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C057/C057_val_log2fc"}
interpro_active_site/result.tsv ADDED
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+ Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
2
+ Ubiquitin-activating enzyme E1, Cys active site [IPR033127] 0.7488282326991985 0.9429077023470646 0.3457281148418578 0.9999999999685064 0.5185921722627868 3 Q9UBT2,P22314 2
3
+ Thiolase, active site [IPR020610] 0.5054852318969566 0.6080018282469704 0.5431862613355052 1.0 0.7006583390635989 5 P24752,P42765,P55084 3
4
+ Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999] 0.6117088983662013 0.4615336101527307 0.644415813536587 1.0 0.7985152472083795 3 Q16881 1
5
+ ATP:guanido phosphotransferase active site [IPR022415] 0.5722160970231421 0.3789948062627716 0.7046917206616017 1.0 0.8546261293130063 2 P12532 1
6
+ Thiolase, acyl-enzyme intermediate active site [IPR020615] 0.4127557511531085 0.2753231721784923 0.78306796332388 1.0 0.9109157940706358 5 P24752,P42765,P55084 3
7
+ Malate dehydrogenase, active site [IPR001252] 0.4385336273428749 0.0859296889292064 0.931522310438931 1.0 0.9873195015211924 2 P40925 1
8
+ Ribonucleotide reductase small subunit, acitve site [IPR030475] 0.41179713340682 0.0571188673864634 0.9544505069578142 1.0 0.9873195015211924 2 Q7LG56 1
9
+ Serine/threonine-protein kinase, active site [IPR008271] 0.1968286886207173 0.0451156924892723 0.964015093360798 1.0 0.9873195015211924 57 Q13464,P51956,O00311,Q2M2I8,Q9H2G2,Q9Y5S2 6
10
+ Peptidase S16, active site [IPR008268] 0.3864388092612875 0.0376106621673859 0.9699981067576626 1.0 0.9873195015211924 2 P36776 1
11
+ Ubiquitin-conjugating enzyme, active site [IPR023313] 0.2284768211920498 0.0067415034217495 0.9946210992464796 1.0 0.9946210992464796 6 P61086,P68036,Q16763,P61088,P60604 5
interpro_active_site/selections.json ADDED
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+ {"all_annotations": ["ATP synthase, F0 complex, subunit A, active site [IPR023011]", "ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenosine/AMP deaminase active site [IPR006650]", "Adenylosuccinate synthase, active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Coenzyme A transferase active site [IPR004164]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "DNA/RNA non-specific endonuclease, active site [IPR018524]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glutaredoxin active site [IPR011767]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycoside hydrolase, family 2, active site [IPR023232]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Lipase, GDXG, putative serine active site [IPR033140]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]", "Uracil-DNA glycosylase, active site [IPR018085]"], "available_proteins": ["AAK1", "ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADA", "ADSS", "AKT1", "AKT2", "AMPD2", "APEH", "ATP5A1", "ATP5B", "ATP6", "ATP6V1A", "ATP6V1B2", "AURKA", "AURKB", "BLMH", "CAMK1", "CAMK2G", "CAPN1", "CAPN2", "CAPN5", "CDC42BPB", "CDC7", "CDK1", "CDK11B", "CDK16", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CHEK2", "CHUK", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CTSA", "CTSC", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "ENDOG", "EPHA7", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLRX", "GSK3A", "GSK3B", "GSR", "GUSB", "HADHB", "HMGCL", "HMGCS1", "IKBKB", "LDHA", "LDHB", "LONP1", "LONP2", "MAP2K1", "MAP3K7", "MAPK1", "MAPK3", "MARK2", "MASTL", "MDH1", "MDH2", "NCEH1", "NEK3", "NEK9", "NME1", "NME2", "OXCT1", "PAK2", "PBK", "PGAM1", "PIK3R4", "PKM", "PKMYT1", "PKN1", "PKN2", "PLK1", "PREP", "PRKAA2", "PRKACA", "PRKCD", "PRPF4B", "PTK7", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "RIPK1", "RNASET2", "RNGTT", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "RRM2", "RRM2B", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SUCLG1", "TALDO1", "TIGAR", "TOP1", "TPI1", "TPP2", "TTK", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "UMPS", "UNG", "VRK1", "VRK2", "WNK1"], "leading_proteins": ["AAK1", "ACAA2", "ACAT1", "CDC42BPB", "CDC7", "CKMT1A*", "HADHB", "LONP1", "MDH1", "NEK3", "ROCK1", "RRM2B", "SLK", "TXNRD1", "UBA1", "UBA2", "UBE2G2", "UBE2K", "UBE2L3", "UBE2N", "UBE2S"]}
interpro_binding_site/advanced/idx2term.json ADDED
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+ term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500
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+ IQ motif, EF-hand binding site [IPR000048] 9 12 2.6203436625621785 0.0087841196022806 4.902912621359223 10.79368932038835 -0.2273048691062784 0.5134620963427197 2.787853554074696 2.339749173467172 1.002129759133213 0.3214407723554939 1.0 0.1788224008957527 0.0583817580096799 0.0161470643842222 0.0028781147210985
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+ {
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+ "signature_size": 3630,
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+ "annotations_size": 33,
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+ "title": "Average number of proteins per term",
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+ "value": 4.818181818181818
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+ {"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C057/C057_val_log2fc"}
interpro_binding_site/result.tsv ADDED
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+ Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
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+ IQ motif, EF-hand binding site [IPR000048] 0.7023786711577714 2.6203436625621785 0.0087841196022806 0.252601377148282 0.0598252310652483 12 Q15051,Q92614,Q86VI3,Q7Z406,P35580,O00159,P35579,O94832,O43795 9
3
+ PPM-type phosphatase, divalent cation binding [IPR000222] 0.6441700337790095 1.0011911144917234 0.3167344214866063 0.9999965209962236 0.5406841854550489 4 Q9P0J1 1
4
+ Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838] 0.6105292171995493 0.5045445617652295 0.61387875606005 0.999999999999977 0.8440832895825688 2 P00505 1
5
+ 2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016] 0.4484280198565903 0.2797323317268093 0.7796828710492696 1.0 0.8865483339202777 4 P36957,P10515,P11182 3
6
+ Aconitase family, 4Fe-4S cluster binding site [IPR018136] 0.5361080485115709 0.2756989823638686 0.7827792773058038 1.0 0.8865483339202777 2 Q99798 1
7
+ Protein kinase, ATP binding site [IPR017441] 0.2278827345769233 0.2456501932920296 0.8059530308366161 1.0 0.8865483339202777 51 Q13464,Q16513,P51956,O00311,O96013,O95747,Q13043,Q99640,Q9H2G2,O75116,P11802,Q9Y5S2 12
interpro_binding_site/selections.json ADDED
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+ {"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "APOBEC/CMP deaminase, zinc-binding [IPR016192]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Coenzyme A transferase binding site [IPR004163]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit I, copper-binding site [IPR023615]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]", "Ureohydrolase, manganese-binding site [IPR020855]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "AKT1", "AKT2", "APEX1", "APOBEC3C", "ARG2", "AURKA", "AURKB", "BPNT1", "CALM3", "CALU", "CAMK1", "CAMK2G", "CAPN1", "CAPN2", "CAPNS1", "CDC42BPB", "CDC7", "CDK1", "CDK16", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CETN2", "CHUK", "COX1", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CYB5B", "DBT", "DLAT", "DLST", "DST", "EHD1", "EHD4", "EIF2AK2", "EPHA7", "EPS15", "EPS15L1", "FKBP10", "FKBP14", "FKBP7", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3A", "GSK3B", "HK1", "HK2", "HMBS", "IDE", "ILKAP", "IQCB1", "IQGAP1", "IQGAP2", "IQGAP3", "ITSN2", "LETM1", "MACF1", "MAP2K1", "MAP3K7", "MAPK1", "MAPK14", "MAPK3", "MARK2", "MCCC1", "MCFD2", "METAP2", "MICU1", "MYH10", "MYH14", "MYH9", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "NEK3", "NFS1", "NRDC", "NUCB1", "NUCB2", "OXCT1", "OXSR1", "PA2G4", "PAK2", "PAK4", "PC", "PCCA", "PDCD6", "PDHX", "PDP1", "PEF1", "PGD", "PKMYT1", "PKN1", "PKN2", "PLCG1", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1F", "PPM1G", "PRKAA2", "PRKACA", "PRKCD", "PRKCSH", "PSAT1", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "S100A11", "SDF4", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "STK26", "STK4", "TKT", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "UBE3C", "UQCRC2", "VRK1"], "leading_proteins": ["ACO2", "CDC42BPB", "CDC7", "CDK4", "DBT", "DLAT", "DLST", "GOT2", "IQCB1", "IQGAP3", "MYH10", "MYH14", "MYH9", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "NEK3", "OXSR1", "PAK4", "PDP1", "PKMYT1", "PKN2", "ROCK1", "ROCK2", "SLK", "STK4"]}
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+ {"0": "Bromodomain, conserved site [IPR018359]", "1": "Zinc finger, PHD-type, conserved site [IPR019786]", "2": "Zinc finger, RING-type, conserved site [IPR017907]", "3": "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "4": "Heat shock protein 70, conserved site [IPR018181]"}
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interpro_conserved_site/basic/idx2term.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {"0": "Bromodomain, conserved site [IPR018359]", "1": "Zinc finger, PHD-type, conserved site [IPR019786]", "2": "Zinc finger, RING-type, conserved site [IPR017907]", "3": "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "4": "Heat shock protein 70, conserved site [IPR018181]", "5": "Actinin-type actin-binding domain, conserved site [IPR001589]", "6": "DnaJ domain, conserved site [IPR018253]", "7": "Kinesin motor domain, conserved site [IPR019821]", "8": "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "9": "Chaperonin TCP-1, conserved site [IPR002194]", "10": "ATPase, AAA-type, conserved site [IPR003960]"}
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interpro_conserved_site/consensus.joblib ADDED
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+ version https://git-lfs.github.com/spec/v1
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+ oid sha256:ac852d1fc85712678cad282ae3052df5627ce603024f9381ac37fc3eea10e853
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+ size 112724
interpro_conserved_site/df_merge.tsv ADDED
@@ -0,0 +1,7 @@
 
 
 
 
 
 
 
 
1
+ term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500
2
+ Bromodomain, conserved site [IPR018359] 7 11 2.3942940369652987 0.0166523930788984 5.529126213592233 9.820388349514564 -0.8552206791946717 0.3841686679671253 2.4920507041843005 1.8359336252623952 0.9945124236501974 0.3161254538359859 1.0 0.1157751708195439 0.2186221342412543 0.4627901258069825 0.1199524552735497
3
+ Intermediate filament protein, conserved site [IPR018039] 3 8 2.2063478693322987 0.0273596520935615 4.060679611650485 7.546116504854369 0.7869831563787604 0.2926647109331939 1.9153715257926656 0.8924219614624045 1.3691577499316503 0.3120813432784052 1.0 1.0 0.1626892876910785 0.0708153438700075 0.0098879726868235
4
+ Zinc finger, PHD-type, conserved site [IPR019786] 8 18 2.194114363751661 0.0282271889017433 7.924757281553398 15.968446601941748 -0.8932990755852599 0.405709433078066 4.135058338809696 3.50470897017074 1.057968995875309 0.3390198533771147 1.0 1.0 0.1043706933170995 0.4007853524207055 0.0539791573859534
5
+ Zinc finger, RING-type, conserved site [IPR017907] 8 17 2.129306995722241 0.0332288693923552 4.609223300970874 14.776699029126211 -0.045326225777209 0.5577732895844865 3.238903742779499 4.550007017672923 0.8841385018499901 0.2924846286854669 1.0 0.0876325329480415 0.0767446240128207 0.4522434981148837 0.7323442203982553
6
+ Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892] 5 13 2.082366322184312 0.0373090221723495 4.951456310679611 9.776699029126211 -0.8483999101163021 0.4005956075506935 2.187247420210493 1.8164942167575489 0.9035429813719144 0.3144938579483745 1.0 1.0 1.0 0.0064387619157215 0.0063533232968262
7
+ Heat shock protein 70, conserved site [IPR018181] 6 10 2.04187738612514 0.0411636954671221 5.157766990291262 9.618932038834952 -0.5977526314899951 0.5182608346902362 2.6978709448427782 0.6407904897015557 0.7298098612304945 0.3042104761407978 1.0 1.0 1.0 0.2577455317022596 0.113339965404402
interpro_conserved_site/metrics.json ADDED
@@ -0,0 +1,7 @@
 
 
 
 
 
 
 
 
1
+ {
2
+ "type_of_task": "ranksum",
3
+ "signature_size": 3630,
4
+ "annotations_size": 290,
5
+ "title": "Average number of proteins per term",
6
+ "value": 2.8241379310344827
7
+ }
interpro_conserved_site/paths.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C057/C057_val_log2fc"}
interpro_conserved_site/result.tsv ADDED
@@ -0,0 +1,59 @@
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
1
+ Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
2
+ Bromodomain, conserved site [IPR018359] 0.6788587103071793 2.3942940369652987 0.0166523930788984 0.9923255207926898 0.1097544089291032 11 Q86U86,O60885,Q15059,Q12830,Q9NRL2,P25440,Q9UIG0 7
3
+ Intermediate filament protein, conserved site [IPR018039] 0.703155027164301 2.2063478693322987 0.0273596520935615 0.9996792537397 0.1469314649469043 8 Q03252,P07197,P48681 3
4
+ Zinc finger, PHD-type, conserved site [IPR019786] 0.5469739815948695 2.194114363751661 0.0282271889017433 0.9997523856917572 0.1488342687546468 18 Q96T23,Q9UIG0,Q12830,Q9Y2K7,Q92576,O94880,Q9BTC0,Q96L73 8
5
+ Zinc finger, RING-type, conserved site [IPR017907] 0.5456203145342507 2.1293069957222412 0.0332288693923552 0.9999445546383492 0.1690591600663688 17 Q14527,O60858,Q99496,O75150,P14373,Q13049,O15344,Q99590 8
6
+ Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892] 0.5924653288973027 2.0823663221843116 0.0373090221723495 0.9999837369688608 0.1717399433330376 13 Q9Y3C6,Q13356,P30414,Q13427,Q6UX04 5
7
+ Heat shock protein 70, conserved site [IPR018181] 0.6310757041328163 2.0418773861251394 0.0411636954671221 0.9999949196207824 0.1865229950853973 10 P34932,P0DMV9,O95757,P54652,P11142,Q9Y4L1 6
8
+ Actinin-type actin-binding domain, conserved site [IPR001589] 0.5450998586539562 1.8997772895150435 0.0574623524761221 0.999999964793344 0.2109377495958916 14 Q14315,O75369,Q01082,P21333,P46939 5
9
+ DnaJ domain, conserved site [IPR018253] 0.5493048551630404 1.8062343960157996 0.0708817343400969 0.9999999994497129 0.2335875336207739 13 Q5F1R6,Q8WXX5,O75190,Q99543,Q96EY1,P25685,Q9NXW2 7
10
+ FERM conserved site [IPR019747] 0.6258731938875406 1.7930097298110963 0.07297136830346 0.9999999997135738 0.2377718742472294 8 Q9Y2J2,O43491,Q9Y490 3
11
+ Ribosomal protein L7Ae conserved site [IPR004037] 0.8993936052921853 1.6802568705745655 0.0929073486053986 0.9999999999994764 0.2777642380986144 2 P62424 1
12
+ Kinesin motor domain, conserved site [IPR019821] 0.5177210386375443 1.600688128733997 0.1094460117906153 0.9999999999999974 0.308148965235713 13 Q99661,Q02241,Q9Y496,Q14807,Q86Y91,Q96Q89,O00139,P33176 8
13
+ Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818] 0.7275148223035852 1.5886576497296985 0.1121377051227752 0.999999999999999 0.3097136617676648 5 P48735 1
14
+ Adenylate kinase, conserved site [IPR033690] 0.7259090751719876 1.5814618300886831 0.1137724797837465 0.9999999999999992 0.3112643314838347 5 P27144,Q9UIJ7 2
15
+ Ribosomal protein L24e, conserved site [IPR023442] 0.8539140022050822 1.487196419244592 0.1369629415228848 1.0 0.3413127732417349 2 Q9UHA3 1
16
+ Guanylate kinase, conserved site [IPR020590] 0.591836842002158 1.3955894181089306 0.1628381708251307 1.0 0.3660703065061079 7 Q8N3R9 1
17
+ Ribosomal S11, conserved site [IPR018102] 0.7965821389195332 1.243616951273579 0.2136405743789753 1.0 0.4363082152810059 2 P82912 1
18
+ Ubiquitin-activating enzyme E1, conserved site [IPR018074] 0.7910694597574397 1.2202845690283952 0.2223570173962055 1.0 0.4380596422137154 2 Q9UBT2 1
19
+ Mini-chromosome maintenance, conserved site [IPR018525] 0.5862873484644919 1.1855887615813745 0.2357847425991412 1.0 0.4502377006457545 6 P33991 1
20
+ Ribosomal protein L24/L26, conserved site [IPR005825] 0.7690187431091748 1.1272908470243848 0.2596195309950788 1.0 0.4697413659573012 2 P61254 1
21
+ Chromo domain, conserved site [IPR023779] 0.6130484839376409 1.0729077196873664 0.283312522076093 1.0 0.494943562663054 5 P45973,O14646,Q13185 3
22
+ Vinculin, conserved site [IPR000633] 0.7475192943770839 1.0373364048599618 0.2995791051352816 1.0 0.5202271885582734 2 P18206 1
23
+ HMG box A DNA-binding domain, conserved site [IPR017967] 0.7683876154021982 1.017215074089716 0.3090511265806719 1.0 0.5303244183928689 3 P26583 1
24
+ Enolase, conserved site [IPR020809] 0.7392502756339656 1.0029873948620576 0.3158669431358314 1.0 0.5388318441728889 2 P09104 1
25
+ Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867] 0.7086549062844847 0.8774972371609495 0.3802166188448967 1.0 0.605839667390346 2 P13995 1
26
+ Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628] 0.7086549062844487 0.877497237160804 0.3802166188449758 1.0 0.605839667390346 2 Q6UB35 1
27
+ Ubiquitin specific protease, conserved site [IPR018200] 0.3750883376559872 0.8518544614743688 0.3942948744832553 1.0 0.6143111881456154 16 P40818,Q9UPT9 2
28
+ Ubiquitin interacting motif [IPR003903] 0.5577950991264691 0.8283879103890154 0.4074508509890702 1.0 0.6143111881456154 5 O14964 1
29
+ AT hook, DNA-binding motif [IPR017956] 0.7179487179487157 0.8274655486570826 0.4079732411701902 1.0 0.6143111881456154 3 P17096,Q6ZRS2 2
30
+ Ribosomal protein L13, conserved site [IPR023563] 0.6948732083792666 0.8219971075503235 0.4110785431085282 1.0 0.6143111881456154 2 P40429 1
31
+ Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364] 0.5963237541118293 0.8041725570795594 0.4212973254774659 1.0 0.6201838801444929 4 Q8N4Q0 1
32
+ Sterol reductase, conserved site [IPR018083] 0.7094017094017071 0.7960212768256032 0.4260196686636555 1.0 0.6239682015780812 3 Q9UBM7,Q14739 2
33
+ Heat shock protein Hsp90, conserved site [IPR019805] 0.6779707747449657 0.682814581594123 0.4947240144727556 1.0 0.6655282463607912 3 P08238,P07900 2
34
+ Integrin alpha chain, C-terminal cytoplasmic region, conserved site [IPR018184] 0.6579382579933771 0.6775125669110134 0.4980807994076306 1.0 0.6656379346922252 2 P17301 1
35
+ Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331] 0.653432588916457 0.597686279214282 0.5500492823099699 1.0 0.6905380600428193 3 Q12979,P11274 2
36
+ ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629] 0.3227154575413112 0.5798516025625671 0.5620146953827982 1.0 0.6995032689313797 20 Q7L014,Q9UHI6,Q8TDD1,Q9BUQ8,Q96GQ7,Q86XP3 6
37
+ Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326] 0.6287210584343903 0.5689227118842016 0.5694085915172153 1.0 0.705677314273472 2 P29692 1
38
+ Dynamin, GTPase region, conserved site [IPR019762] 0.6317876760375625 0.5255406731369835 0.5992073864271836 1.0 0.7332073504805201 3 P50570 1
39
+ EGF-like, conserved site [IPR013032] 0.6108048511576731 0.50549910295355 0.6132083283462912 1.0 0.7440603147298095 2 Q04721 1
40
+ S100/Calbindin-D9k, conserved site [IPR001751] 0.5931642778390305 0.445818303422338 0.6557284992599026 1.0 0.7825566452072912 2 P60903 1
41
+ Alcohol dehydrogenase, zinc-type, conserved site [IPR002328] 0.572491730981246 0.3798432449494334 0.7040617791071386 1.0 0.8272400217503861 2 Q00796 1
42
+ Polyprenyl synthetase, conserved site [IPR033749] 0.5831265508684829 0.3760944354141106 0.7068466910533069 1.0 0.8272400217503861 3 O95749,Q5T2R2 2
43
+ Alpha-D-phosphohexomutase, conserved site [IPR016066] 0.5828508409153534 0.3753060782797348 0.7074328461865371 1.0 0.8272400217503861 3 Q96G03,O95394 2
44
+ Chaperonin TCP-1, conserved site [IPR002194] 0.3522915516289326 0.350650932658813 0.7258502409336207 1.0 0.8453677504849397 8 P50991,P40227,P78371,P48643,P49368,P17987,P50990 7
45
+ Thiolase, conserved site [IPR020613] 0.3642229510981465 0.2337243763811717 0.8151989622078244 1.0 0.9234675743760512 6 P55084 1
46
+ Cadherin conserved site [IPR020894] 0.3944571958587227 0.1494362344691389 0.8812094217419864 1.0 0.9684559654206768 4 P19022,O60245 2
47
+ Clathrin adaptor complex, small chain [IPR000804] 0.3640696096751197 0.1489046412418173 0.8816288788657196 1.0 0.9684559654206768 5 P61923 1
48
+ Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131] 0.4705071664828955 0.1330524162178443 0.8941519268179388 1.0 0.9720194378433132 2 Q9NQW7 1
49
+ D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753] 0.3781025923883083 0.1187439634938768 0.9054782050957372 1.0 0.9720194378433132 4 Q9UBQ7,Q13363,P56545 3
50
+ IMP dehydrogenase / GMP reductase, conserved site [IPR015875] 0.436879823594252 0.0838787060090152 0.9331528700302772 1.0 0.990734159002388 2 P20839 1
51
+ Procollagen-lysine 5-dioxygenase, conserved site [IPR001006] 0.4316674893773206 0.0728253154371377 0.9419451256348372 1.0 0.990734159002388 3 Q02809 1
52
+ Phosphorylase pyridoxal-phosphate attachment site [IPR035090] 0.42282249173097 0.0679010457065467 0.9458644063227912 1.0 0.990734159002388 2 P06737 1
53
+ Ribosomal protein S5, N-terminal, conserved site [IPR018192] 0.4222712238147619 0.067326302426708 0.9463219380815912 1.0 0.990734159002388 2 P82675 1
54
+ Ras GTPase-activating protein, conserved site [IPR023152] 0.3951373381128792 0.0404017264453191 0.9677728538703316 1.0 0.9908240729672136 3 Q86VI3 1
55
+ Thioredoxin, conserved site [IPR017937] 0.2198671393710627 0.0342842501745252 0.9726504840268672 1.0 0.9908240729672136 12 P13667,P30101,Q8NBS9 3
56
+ Oxysterol-binding protein, conserved site [IPR018494] 0.2579062764312614 0.027251454495461 0.9782591761726058 1.0 0.9908240729672136 6 P22059 1
57
+ ATPase, AAA-type, conserved site [IPR003960] 0.1959634974046828 0.0242414318161882 0.9806600300199332 1.0 0.9908240729672136 23 O15381,P35998,O75449,P62195,Q9BVQ7,P17980,P62333,Q8NB90,Q9Y4W6,P62191,Q96TA2,P55072,Q9UN37 13
58
+ Ribosomal protein L3, conserved site [IPR019926] 0.3183572216096931 0.0124190831882696 0.9900912599755604 1.0 0.9908240729672136 2 P39023 1
59
+ DNA mismatch repair, conserved site [IPR014762] 0.3125689084895164 0.0115005725851679 0.9908240729672136 1.0 0.9908240729672136 2 P54277 1
interpro_conserved_site/selections.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Aldose 1-epimerase, conserved site [IPR018052]", "Alpha-2-macroglobulin, conserved site [IPR019742]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Aminotransferase, class IV, conserved site [IPR018300]", "Amyloidogenic glycoprotein, copper-binding domain conserved site [IPR019744]", "Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]", "Anion exchange, conserved site [IPR018241]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "Arrestin, conserved site [IPR017864]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Band 7/stomatin-like, conserved site [IPR018080]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAMSAP, spectrin and Ca2+/calmodulin-binding region [IPR031372]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "CBX family C-terminal motif [IPR033773]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Clusterin, conserved site [IPR033986]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific, conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA mismatch repair, conserved site [IPR014762]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family A, conserved site [IPR019760]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Deoxyribonuclease, TatD-related, conserved site [IPR018228]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dpy-30 motif [IPR007858]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Endonuclease III-like, conserved site-2 [IPR004036]", "Endonuclease III-like, iron-sulphur cluster loop motif [IPR003651]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Ependymin, conserved site [IPR018224]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FHF complex subunit HOOK interacting protein, KELAA motif [IPR045668]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "Fibrillarin, conserved site [IPR020813]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glutathione peroxidase conserved site [IPR029760]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 2, conserved site [IPR023230]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Golgin subfamily A member 2, C-terminal binding motif [IPR043937]", "Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Helix-hairpin-helix motif [IPR000445]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "Homeobox, conserved site [IPR017970]", "Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site [IPR023076]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Integrin alpha chain, C-terminal cytoplasmic region, conserved site [IPR018184]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "MoaA/NifB/PqqE, iron-sulphur binding, conserved site [IPR000385]", "Molybdenum cofactor biosynthesis, conserved site [IPR008284]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NADH:ubiquinone oxidoreductase, subunit 1, conserved site [IPR018086]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site [IPR023058]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosyl pyrophosphate synthetase, conserved site [IPR000842]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Pyridoxamine 5'-phosphate oxidase, conserved site [IPR019740]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RIO kinase, conserved site [IPR018935]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P, conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S14, conserved site [IPR018271]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Transcription factor TFIIB, conserved site [IPR023486]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "Tyrosine-protein kinase, receptor class V, conserved site [IPR001426]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Uncharacterised protein family UPF0029, Impact, conserved site [IPR020569]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]"], "available_proteins": ["AAAS", "AAMP", "ABCB1", "ABCB10", "ABCB6", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABR", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK3", "AK4", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA6", "ANXA7", "AP1M1", "AP1S1", "AP1S2", "AP2M1", "AP2S1", "AP3M1", "AP3S1", "AP4M1", "APEX1", "APLP2", "APP", "ARHGEF7", "ARIH2", "ARRB2", "ATAD1", "ATAD2", "ATP5C1", "ATP5O", "BAG6", "BAK1", "BAZ1A", "BAZ1B", "BAZ2A", "BCAT2", "BCR", "BCS1L", "BLM", "BOP1", "BPNT1", "BPTF", "BRCA1", "BRD2", "BRD3", "BRD4", "BUD31", "CAD", "CALR", "CAMSAP3", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CBR1", "CBX1", "CBX3", "CBX5", "CBX8", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CD320", "CDH2", "CDK5RAP1", "CDKAL1", "CENPE", "CETN2", "CHAF1B", "CHD1", "CHD1L", "CHD4", "CLGN", "CLU", "CMPK1", "CNDP2", "COLEC12", "COPA", "COPZ1", "CORO1B", "CORO1C", "CORO7", "CPOX", "CRYZ", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CWC27", "CYP51A1", "DCAF13", "DCAF7", "DCPS", "DCXR", "DDT", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX6", "DHCR7", "DHFR", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIS3", "DLG3", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC16", "DNAJC2", "DNAJC21", "DNAJC9", "DNM1L", "DNM2", "DNM3", "DNMT1", "DPY30", "DRG1", "DRG2", "DSC3", "DSG2", "DST", "DTYMK", "DYNLL1", "DYNLL2", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4E", "EIF4E2", "ENO1", "ENO2", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPN1", "EPRS", "EPS15", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FAM160B2", "FBL", "FDFT1", "FDPS", "FEN1", "FH", "FIGNL1", "FLNA", "FLNB", "FLNC", "FUCA1", "FUCA2", "GAA", "GALK1", "GALM", "GALNS", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GGPS1", "GLA", "GLB1", "GLO1", "GMPPA", "GMPPB", "GNPDA1", "GNS", "GOLGA2", "GPHN", "GPI", "GPX8", "GRHPR", "GRWD1", "GSPT1", "GTF2B", "GTF3C2", "GUF1", "GUSB", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HGS", "HIBADH", "HINT2", "HLA-A", "HLA-B", "HLA-F", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCR", "HMOX1", "HMOX2", "HSD17B10", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "ILVBL", "IMPACT", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "IQGAP1", "IQGAP2", "IQGAP3", "ITGA2", "ITGAV", "IVD", "KATNA1", "KDM2A", "KDSR", "KIF11", "KIF18B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "LAMP1", "LAMP2", "LARS", "LARS2", "LBR", "LDLR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK14", "MAPK3", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME1", "ME2", "MGST2", "MID1", "MIF", "MOCS1", "MPI", "MPP1", "MPP2", "MPP5", "MPP6", "MPP7", "MPST", "MRPL13", "MRPL24", "MRPL3", "MRPS11", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTF2", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "ND1", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS8", "NDUFV1", "NEFL", "NEFM", "NES", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NOTCH2", "NSD1", "NSD2", "NSD3", "NSF", "NTHL1", "NUBP2", "NUBPL", "NUDT1", "NUDT12", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL11", "OSBPL2", "OSBPL3", "OSBPL8", "OSBPL9", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PAX6", "PBRM1", "PCDH7", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDSS1", "PEBP1", "PEPD", "PEX6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHF14", "PHF3", "PHF8", "PHGDH", "PHIP", "PI4KA", "PI4KB", "PIK3C2A", "PIN1", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PMS1", "PNP", "PNPLA6", "PNPO", "POLA1", "POLD1", "POLG", "POLR1B", "POLR1C", "POLR2B", "POLR2C", "POLR2E", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PRPS1", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PUS7", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "QDPR", "RACK1", "RAE1", "RANBP2", "RARS", "RARS2", "RBBP4", "RBBP7", "RCL1", "RDH13", "RDX", "RIDA", "RIOK2", "RNF14", "RNF2", "RNF20", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS24", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "RSF1", "RSL24D1", "RTCA", "RTN4IP1", "S100A10", "S100A11", "SART1", "SBDS", "SCAF11", "SCD", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB1", "SERPINB6", "SERPINH1", "SLC1A5", "SLC25A42", "SLC27A4", "SLC2A1", "SLC4A2", "SLIT2", "SMARCA4", "SMG1", "SMS", "SMU1", "SNRNP40", "SNU13", "SORD", "SPAST", "SPATA5", "SPATA5L1", "SPTBN1", "SPTBN2", "SRCAP", "SRM", "STAM", "STMN1", "STOM", "STRN", "STX10", "STX12", "STX18", "STX4", "STX5", "STX6", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SV2A", "SYNE2", "TAP1", "TATDN1", "TBL1XR1", "TBL3", "TCP1", "TFB1M", "THOC6", "TK1", "TLE3", "TLN1", "TM7SF2", "TMX1", "TMX3", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRIM13", "TRIM21", "TRIM24", "TRIM25", "TRIM27", "TRIM28", "TRIM32", "TRIM33", "TRIP13", "TRMT11", "TSFM", "TTF2", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUFM", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UBA5", "UBFD1", "UHRF1", "USP1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP22", "USP24", "USP28", "USP38", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VARS2", "VAT1", "VCL", "VCP", "VIM", "VPS4A", "VPS4B", "WARS", "WARS2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR36", "WDR5", "WDR61", "WDR7", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZMYND8"], "leading_proteins": ["ABR", "AFG3L2", "AK3", "AK4", "BAZ1A", "BAZ1B", "BCR", "BPTF", "BRD2", "BRD3", "BRD4", "CBX3", "CBX5", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT8", "CDH2", "CHD1", "COPZ1", "CTBP1", "CTBP2", "CWC27", "DDX20", "DDX23", "DDX27", "DDX42", "DDX46", "DDX54", "DHCR7", "DIDO1", "DNAJA3", "DNAJB1", "DNAJB12", "DNAJB6", "DNAJC2", "DNAJC21", "DNAJC9", "DNM2", "EEF1D", "ENO2", "EPB41L2", "EPB41L3", "FLNA", "FLNB", "FLNC", "GGPS1", "GRHPR", "HADHB", "HGS", "HLTF", "HMGA1", "HMGB2", "HSP90AA1", "HSP90AB1", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HYOU1", "IDH2", "IMPDH1", "IQGAP3", "ITGA2", "KATNA1", "KDM2A", "KIF18B", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF5B", "LBR", "LMNB2", "MCM4", "MID1", "MPP5", "MRPS11", "MRPS5", "MTHFD1L", "MTHFD2", "NEFM", "NES", "NKTR", "NOTCH2", "NSD1", "NVL", "OSBP", "PBRM1", "PCDH7", "PDIA3", "PDIA4", "PDSS1", "PGM2", "PGM3", "PHF14", "PHF3", "PLOD1", "PMS1", "PPIG", "PPIL1", "PPIL2", "PSMC1", "PSMC2", "PSMC3", "PSMC5", "PSMC6", "PYGL", "RNF2", "RNF40", "RPL13A", "RPL26", "RPL3", "RPL7A", "RSF1", "RSL24D1", "S100A10", "SCAF11", "SORD", "SPATA5", "SPATA5L1", "SPTBN1", "SRCAP", "TCP1", "TLN1", "TRIM13", "TRIM27", "TRIM32", "TXNDC5", "UBA2", "USP22", "USP8", "UTRN", "VCL", "VCP", "VPS4A", "XPNPEP1", "YME1L1", "ZADH2"]}
interpro_domain/advanced/idx2term.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {"0": "RNA recognition motif domain [IPR000504]", "1": "Zinc finger C2H2-type [IPR013087]", "2": "K Homology domain, type 1 [IPR004088]", "3": "K Homology domain [IPR004087]", "4": "SAP domain [IPR003034]", "5": "RNA recognition motif domain, eukaryote [IPR003954]", "6": "Myosin head, motor domain [IPR001609]", "7": "Linker histone H1/H5, domain H15 [IPR005818]", "8": "SH3 domain [IPR001452]", "9": "Matrin/U1-C-like, C2H2-type zinc finger [IPR003604]"}
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