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6387108 verified
Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
Eukaryotic translation initiation 0.5201010733756313 4.888851829942161 1.0142579753930886e-06 0.0014392103974013 0.0007201231625298 104 P15880,P05198,P56537,P62847,Q14232,P05387,Q13347,P62841,P83731,Q13144,P62269,P08865,P62913,P18621,P62081,Q07020,P30050,P63220,Q9Y3U8,P61313,Q9UBQ5,P61513,O60841,Q9NR50,P35268,P60842,P08708,P42766,P05388,P39019,P62244,P50914,P46777,P49770,P40429,P62910,P84098,P32969,P46778,P62899,P46776,P62857,Q15056,P63173,Q14240,P61254,P62906,P20042,O75821,P06730,O00303,P62273,P61927,P62249,P62753,P62888,O15372,P62854,P05386,P62701,P60866,P62829,P26373,P62280,P62277,P62263,P61247 67
Response of eif2ak4 gcn2 to amino acid deficiency 0.5307296560898968 4.616394898724937 3.90463626631643e-06 0.0055292514296902 0.0017713019597668 79 P15880,P05198,P62847,P05387,P62841,P83731,P08865,P62913,P18621,P62081,Q07020,P63220,Q9Y3U8,P61313,P61513,P35268,P05388,P08708,P08243,P42766,P39019,P62244,P50914,P46777,P40429,P62910,P84098,P32969,P46778,P62899,P46776,P62857,P63173,P61254,P62906,P20042,P62273,P62249,P62753,P30050,P61927,P60866,P62888,P62854,P05386,P62829,P62701,P62280,P26373,P62277,P62263,P61247 52
Neddylation 0.5263688762067223 4.562927688089924 5.044519292729532e-06 0.0071376406424544 0.0017713019597668 79 P49720,P25787,Q9UBW8,Q9UNS2,O00487,O75147,P48556,Q15369,Q13200,Q9NX08,O00233,Q9BT78,Q9UNM6,Q92905,Q96GG9,Q9UL46,Q86VX2,P63208,P20618,Q15370,P25788,P61081,Q9H2C0,P17980,O75832,P28072,P28074,P61289,P28066,Q7L5N1,Q13098,P62333,Q13564,P25789,Q8TBC4,P61962,Q06323 37
Synthesis of dna 0.4834811423776693 4.515438575861707 6.3185859839887115e-06 0.0089322883963818 0.0017713019597668 90 P49720,P35244,P25787,P12004,Q9UBD5,Q9UJX4,Q9UJX6,Q13042,P40937,O00487,Q9BRX5,P48556,P28070,P20248,Q13200,O00233,O43913,Q9UNM6,Q9Y248,P62191,Q9UL46,P63208,P20618,Q99741,Q9NR33,P25788,Q15054,P39748,Q96DE5,P17980,Q9BRT9,O75832,P28072,P28074,P61289,P28066,P25786,O43929,P62333,P24941,P25789,P15927,Q06323,P49643,Q13309,P18858 46
Eukaryotic translation elongation 0.5188130390513965 4.469703750416469 7.832801188323302e-06 0.0110609935950418 0.0017713019597668 79 P15880,P62847,P05387,P62841,P83731,P08865,P62913,P18621,P62081,Q07020,P63220,Q9Y3U8,P61313,P61513,P35268,P05388,P08708,P42766,P62244,P39019,P50914,P46777,P24534,P40429,P62910,P84098,P32969,P46778,P62899,P46776,P62857,P63173,P61254,Q05639,P62273,P62249,P62753,P62906,P30050,P61927,P60866,P62888,P62854,P05386,P62829,P62701,P62280,P26373,P62277,P62263,P61247 51
Mitotic g1 phase and g1 s transition 0.4967297444740373 4.446408823565625 8.731770224201796e-06 0.0123226148943885 0.0017713019597668 85 P49720,P35244,P00374,P11802,P25787,P12004,P04183,Q9UBD5,O00487,P48556,P28070,P20248,Q13200,O00233,O43913,P07948,Q9UNM6,P31350,P62191,Q9UL46,P63208,P20618,Q99741,Q9NR33,P25788,P42771,P17980,O75832,P28072,P28074,P61289,Q5TKA1,P63151,P28066,P25786,O43929,P62333,P25789,P15927,P06493,Q06323,P49643,Q13309,P24941 44
Cellular response to starvation 0.4727587946079583 4.390994230629172 1.12833534859913e-05 0.0158947756615726 0.0020027952437636 93 P15880,Q9Y664,P05198,P62847,P05387,P62841,P83731,P08865,P62913,P18621,P62081,Q07020,Q9Y2Q5,Q8NFG4,P63220,Q9Y3U8,P61313,P61513,P35268,P61421,P05388,P08708,P08243,P42766,P39019,P62244,P50914,P46777,P40429,P62910,P84098,P32969,P46778,P62899,P46776,P62857,P21283,P63173,P61254,P62906,P20042,P62273,P62249,P62753,P30050,P61927,P60866,P62888,P62854,P05386,P62829,P62701,P62280,P26373,P62277,P62263,P61247 57
Selenoamino acid metabolism 0.4627622053920486 4.265003000845642 1.9989951507648485e-05 0.0279869171201405 0.0031539701267624 92 P62847,P62841,P08865,P62913,Q16881,Q12904,P18621,P62081,Q07020,P63220,Q9Y3U8,P61313,P61513,P57772,P05388,P08708,P00390,Q96I15,P42766,P62244,P50914,P46777,P62910,P84098,P32969,P46778,P62899,P46776,P62857,P63173,O43324,P61254,P62906,P62273,P62249,P62753,P30050,P60866,P61927,P62888,P62854,P05386,P62829,P26373 44
Srp dependent cotranslational protein targeting to membrane 0.456414085079587 4.16019606004034 3.1797451509607555e-05 0.0441488692451044 0.0045152381143644 93 P37108,P49458,P62847,P62841,P08865,P62913,P18621,P62081,P09132,Q07020,Q9Y3U8,P63220,P61313,P61513,P05388,P08708,P42766,P62244,P39019,P50914,P46777,P60059,P62910,P84098,P32969,P46778,P62899,P46776,P62857,P51571,P63173,P61254,P62906,P62273,P62249,P62753,P61009,P04844,P61927,P30050,P60866,P62888,P62854,P05386,P62829,P62701,P62280,P26373,P62277,P62263 50
Dna replication 0.4554118204389509 4.102101875257897 4.094139255150786e-05 0.0564802366593145 0.0046032951269488 96 P49720,P35244,P25787,P12004,Q9UBD5,Q9UJX4,Q9UJX6,Q13042,P40937,O00487,Q9BRX5,P48556,P28070,P20248,Q13200,O00233,O43913,Q9UNM6,Q9Y248,P62191,Q9UL46,P63208,P20618,Q99741,Q9NR33,P25788,Q15054,P39748,Q96DE5,P17980,Q9BRT9,P16104,O75832,P28072,P28074,P61289,P28066,P25786,O43929,P62333,P24941,P25789,P15927,Q06323,P49643,Q13309,P18858 47
Fceri mediated nf kb activation 0.5559219166087114 4.095401453705857 4.2143746574518914e-05 0.0580898406547615 0.0046032951269488 48 P49720,P25787,O00487,P48556,Q13200,O00233,P07948,Q9UNM6,P62191,Q9UL46,P63208,P20618,O95999,P25788,Q15750,P17980,O75832,P28072,P28074,P61289,P28066,P62333,Q13404,P25789,Q06323,P49427,Q9UDY8 27
Cyclin a cdk2 associated events at s phase entry 0.5564583632299167 4.087575952272646 4.3590398689730137e-05 0.0600228525771081 0.0046032951269488 47 P49720,P25787,P11802,O00487,P48556,P28070,Q13200,O00233,Q9UNM6,P62191,Q9UL46,P63208,P20618,P25788,P17980,O75832,P28072,P28074,P61289,Q5TKA1,P28066,P25786,P62333,P25789,Q06323,Q13309,P24941 27
Scf skp2 mediated degradation of p27 p21 0.59585794753598 4.016401160938282 5.909363113953958e-05 0.0804909895350943 0.0055941970812098 42 P49720,P25787,P11802,O00487,P48556,P28070,Q13200,O00233,Q9UNM6,P62191,Q9UL46,P63208,P20618,P25788,P17980,O75832,P28072,P28074,P61289,P28066,P25786,P62333,P25789,Q06323,Q13309,P24941 26
Activation of the mrna upon binding of the cap binding complex and eifs and subsequent binding to 43s 0.5292965805590892 3.889094201557368 0.000100619059604 0.1331473350807603 0.0088269582052276 53 P15880,P05198,P56537,P62847,Q13347,P62841,P08865,P62081,P63220,Q9UBQ5,P60842,P62244,P08708,P39019,P62857,Q15056,Q14240,O00303,P62249,P62753,O75821,P60866,P06730,P20042,P62273,O15372,P62854,P62280,P62701,P62277,P62263,P61247 32
Interleukin 1 signaling 0.5323885252820442 3.8771784499015673 0.0001056748517527 0.1393490166866871 0.0088269582052276 50 P49720,P25787,P09429,O00487,P48556,Q13200,O00233,Q9UNM6,P52564,P62191,Q9UL46,P63208,P20618,P51617,P25788,Q15750,P17980,O75832,P28072,P28074,P61289,P28066,P62333,Q13404,P25789,Q06323 26
Regulation of expression of slits and robos 0.4681238316739327 3.862875074390795 0.0001120603215081 0.1471184236237355 0.0088403142523075 128 P49720,P25787,P62847,P62841,Q9Y5S9,O00487,P08865,P48556,P62913,Q15369,Q13200,P18621,P62081,O00233,Q07020,P63220,Q9Y3U8,P61313,Q9UNM6,P61513,P62191,Q9UL46,P20618,P08708,P42766,P05388,P62244,P50914,Q15370,P46777,P25788,A7E2V4,P62910,P84098,P32969,P46778,P17980,O75832,P62899,P28072,P28074,P46776,P62495,P62857,P61289,P28066,P25786,P63173,P62333,P61254,P62906,P62273,P62249,P62753,P25789,P30050,P61927,P60866,P62888,P62854,P05386,Q06323,P62829,P26373 64
Regulation of hmox1 expression and activity 0.5289792956322433 3.81464425819593 0.000136379251439 0.176071680494009 0.0101925545812347 48 P49720,P25787,P19784,O00487,P48556,Q13200,O00233,Q9UNM6,P62191,Q9UL46,P63208,P20618,P25788,P17980,P67870,O75832,P28072,P28074,P61289,P28066,P62333,P25789,Q8TCT9,Q06323,Q13309 25
Dectin 1 mediated noncanonical nf kb signaling 0.5709243985358576 3.7829141677164433 0.0001550028767789 0.1975784174268055 0.0110052042513049 42 P49720,P25787,O00487,P48556,Q13200,O00233,Q9UNM6,Q9UL46,P63208,P20618,P25788,P61081,O75832,P28072,P28074,P61289,P28066,P62333,P25789,Q8TBC4,Q06323 21
Regulation of runx3 expression and activity 0.5917951690815767 3.764212262554011 0.0001670749235223 0.2112187234264285 0.0112974472096034 39 P49720,P25787,Q13951,O00487,P48556,Q13200,O00233,Q9UNM6,Q9UL46,P20618,P25788,P42771,O75832,P28072,P28074,P61289,P28066,P62333,P25789,Q06323 20
Tnfr2 non canonical nf kb pathway 0.5569125724449275 3.7267073285114374 0.0001939975024691 0.2408099804900794 0.0123220797921431 43 P49720,P25787,O00487,P48556,Q13200,O00233,Q9UNM6,Q9UL46,P63208,P20618,P25788,P61081,O75832,P28072,P28074,P61289,P28066,P62333,P25789,Q8TBC4,Q06323 21
Hedgehog off state 0.513587195719795 3.718231279556781 0.0002006225527981 0.2479200211819259 0.0123220797921431 53 P49720,P25787,P17612,O00487,P48556,P28070,Q13200,O00233,P04350,Q9BUF5,Q9UNM6,P62191,Q9UL46,P63208,P20618,P25788,Q9BVA1,Q8NCM8,P17980,O75832,P28072,P28074,P61289,P28066,P25786,P62333,P25789,Q06323 28
Negative regulation of notch4 signaling 0.5784085169757766 3.708779723773217 0.0002082605035291 0.2560345725560968 0.0123220797921431 40 P49720,P25787,Q9Y6A5,O00487,P48556,Q13200,O00233,Q9UNM6,P62191,Q9UL46,P63208,P20618,P25788,P17980,O75832,P28072,P28074,P61289,P28066,P25786,P62333,P25789,Q06323 23
Orc1 removal from chromatin 0.5096874529441042 3.690824833969202 0.0002235280341902 0.271993490229312 0.0124095537247829 54 P49720,Q9UBD5,P25787,O00487,P48556,P28070,Q13200,O00233,O43913,Q9UNM6,P62191,Q9UL46,P63208,Q99741,P20618,P25788,P17980,O75832,P28072,P28074,P61289,P28066,P25786,O43929,P62333,P25789,Q06323,Q13309,P24941 29
Cellular response to hypoxia 0.5512643096999552 3.671694555010984 0.0002409475505558 0.2897844389932626 0.0124095537247829 43 P49720,P25787,O00487,P48556,Q15369,Q13200,O00233,Q9UNM6,Q9UL46,P20618,Q15370,P25788,Q9Y241,O75832,P28072,P28074,P61289,P28066,P62333,P25789,Q06323 21
Apc c mediated degradation of cell cycle proteins 0.4963319430030566 3.646542725068707 0.0002657923015636 0.314409820292781 0.0124095537247829 60 P49720,P25787,Q9UJX4,Q13042,Q9UJX6,O43684,O00487,P48556,P28070,Q13200,O00233,Q9UNM6,P62191,Q9UL46,P63208,P20618,P25788,O14965,Q96DE5,P17980,O75832,P28072,P28074,P61289,P28066,P25786,Q13257,P62333,P25789,P06493,Q06323,Q13309,P24941 33
G1 s dna damage checkpoints 0.5485245408650337 3.644904614195744 0.0002674909933784 0.316062008502766 0.0124095537247829 43 P49720,P25787,O00487,P48556,P28070,Q13200,O00233,Q9UNM6,O96017,P62191,Q9UL46,P20618,P25788,P42771,P17980,O75832,P28072,P28074,P61289,P28066,P25786,P62333,P25789,Q06323,P24941 25
Degradation of gli1 by the proteasome 0.5561288481143116 3.641821656401424 0.0002707155993981 0.3191874000043805 0.0124095537247829 42 P49720,P25787,P17612,O00487,P48556,Q13200,O00233,Q9UNM6,Q9UL46,P63208,P20618,P25788,O75832,P28072,P28074,P61289,P28066,P62333,P25789,Q06323 20
Nonsense mediated decay nmd 0.4251578363816518 3.64163424406991 0.0002709127925832 0.3193780622222775 0.0124095537247829 89 P62847,P62841,Q9Y5S9,P08865,P62913,P18621,P30153,P62081,Q07020,P63220,Q9Y3U8,P61313,P61513,P05388,P08708,P42766,P62244,P39019,P50914,P46777,P62910,P84098,P32969,P46778,P62899,P46776,P62495,P62857,P63151,P63173,P61254,P62906,P62273,P62249,P62753,P30050,P60866,P61927,P62888,P62854,P05386,P62829,P62701,Q8ND04,P62280,P26373,P62277,P62263 48
Regulation of pten stability and activity 0.5448577915851006 3.608942225743821 0.0003074480643718 0.3537981595143994 0.0132295833760023 43 P49720,P25787,P19784,O00487,P48556,Q13200,O00233,Q9UNE7,Q9UNM6,Q9UL46,P20618,P25788,P67870,O75832,P28072,P28074,P61289,P28066,P62333,P25789,Q06323 21
Resolution of abasic sites ap sites 0.634372633208094 3.573166516823378 0.0003526903233439 0.3940201820311874 0.0136046708977793 28 Q9UGN5,P27695,Q15054,P35244,Q96T60,P39748,P15927,P18887,P78549,P40937,P29372,P18858,Q9NR33 13
Downstream signaling events of b cell receptor bcr 0.5061031881749748 3.570318300530102 0.000356547706134 0.3973315235960833 0.0136046708977793 48 P49720,P25787,O00487,P48556,Q13200,O00233,Q9UNM6,Q9UL46,P63208,P20618,O95999,P25788,O75832,P28072,P28074,P61289,P28066,P62333,P25789,Q06323,Q9UDY8 21
Clec7a dectin 1 signaling 0.4955326156228424 3.564846887466714 0.0003640686578278 0.4037359210801474 0.0136046708977793 56 P49720,P25787,O00487,P48556,Q13200,O00233,Q9UNM6,Q9UL46,P63208,P20618,O95999,P25788,P61081,Q15750,O75832,P28072,P28074,P61289,P28066,P62333,Q13404,P25789,Q8TBC4,Q06323,P49427,Q9UDY8 26
Tcr signaling 0.4981628868156919 3.5478153787226767 0.0003884403966445 0.4240258628088555 0.0141432144419294 53 P49720,P25787,O00487,P48556,Q13200,O00233,Q9UNM6,Q9UL46,P63208,P20618,O95999,P25788,O75832,P28072,P28074,P61289,P28066,P62333,Q13404,P25789,Q06323,P49427,P50552,Q9UDY8 24
Stabilization of p53 0.5491219637100839 3.5028838520873244 0.0004602501062656 0.4798851344304998 0.015940369534077 41 P49720,P25787,O00487,P48556,Q13200,O00233,Q9UNM6,O96017,Q9UL46,P20618,P25788,P42771,O75832,P28072,P28074,P61289,P28066,P62333,P25789,Q06323 20
Regulation of runx2 expression and activity 0.5237613202977403 3.478056174074689 0.0005050640689114 0.5119669512417601 0.0170759756631979 44 P49720,P25787,Q13951,O00487,P48556,Q13200,O00233,Q9UNE7,Q9UNM6,P62191,Q9UL46,P63208,P20618,P25788,P17980,O75832,P28072,P28074,P61289,P28066,P62333,P25789,Q06323,Q13309 24
Signaling by notch4 0.522915276697698 3.469462605015564 0.0005215006593075 0.5232314362138107 0.017221649679459 44 P49720,P25787,Q9Y6A5,O00487,P48556,Q13200,O00233,Q04721,Q9UNM6,P62191,Q9UL46,P63208,P20618,P25788,P17980,O75832,P28072,P28074,P61289,P28066,P25786,P62333,P25789,Q06323 24
Degradation of beta catenin by the destruction complex 0.4928385366299228 3.448905478597986 0.0005628636920209 0.5504424787817873 0.0180956720682906 50 P49720,P25787,O00487,P48556,Q13200,Q13362,O00233,Q9UNM6,Q9UL46,P63208,P20618,P25788,Q13363,O75832,P28072,P28074,P61289,P28066,P62333,P25789,Q06323 21
Abc family proteins mediated transport 0.491263564848191 3.443868567511018 0.0005734543965303 0.5571564873096218 0.0180956720682906 51 P49720,P25787,O00487,P48556,P40855,Q13200,O75477,O00233,Q9UNM6,Q9UL46,P20618,P25788,Q9NRK6,O75832,P28072,P28074,P61289,P28066,P62333,P25789,Q06323 21
Metabolism of polyamines 0.543948604171274 3.3872582095561303 0.0007059491262852 0.633149827829605 0.0204879828036633 40 P49720,P25787,O00487,P48556,Q13200,P19623,O00233,Q9UNM6,Q9UL46,P20618,P25788,O75832,P28072,P28074,P61289,P28066,P62333,P25789,Q06323,P52788 20
Signaling by robo receptors 0.450703123996138 3.3870770035129643 0.0007064155742579 0.6333929044325891 0.0204879828036633 147 P49720,P25787,P62847,P62841,Q9Y5S9,P17612,O00487,P08865,P48556,P62913,Q15369,Q13200,P18621,P62081,O00233,Q07020,P63220,Q9Y3U8,P61313,Q9UNM6,P61513,P62191,Q9UL46,P20618,P08708,P42766,P05388,P62244,P50914,Q15370,P46777,P25788,P61586,A7E2V4,P62910,P84098,P32969,P46778,P35080,P17980,P07737,O75832,P62899,P28072,P28074,P46776,P62495,P62857,P61289,P28066,P25786,P63173,P62333,P61254,O43639,P62906,P62273,P62249,P25789,P62753,P61927,P30050,P60866,P62888,P62854,P05386,Q06323,P62829,P26373,P50552 70
Cdt1 association with the cdc6 orc origin complex 0.5218764597332112 3.3806821932996827 0.0007230612076294 0.6419627666780096 0.0204879828036633 43 P49720,Q9UBD5,P25787,O00487,P48556,Q13200,O00233,O43913,Q9UNM6,P62191,Q9UL46,Q99741,P20618,P25788,P17980,O75832,P28072,P28074,P61289,P28066,O43929,P62333,P25789,Q06323 24
S phase 0.4143466246409518 3.3670813327242595 0.0007596827972295 0.6601189357000286 0.0204879828036633 105 Q56NI9,P49720,P35244,P25787,P11802,P12004,Q9UBD5,Q9UJX4,Q9UJX6,Q13042,P40937,O00487,Q9BRX5,P48556,P28070,P20248,Q13200,O00233,O43913,Q9UNM6,Q9Y248,P62191,Q9UL46,P63208,P20618,Q99741,Q9NR33,P25788,Q15054,P39748,Q96DE5,P17980,Q9BRT9,O75832,P28072,P28074,P61289,Q5TKA1,P28066,P25786,O43929,P62333,P24941,P25789,P15927,Q06323,P49643,Q13309,P18858 49
Runx1 regulates transcription of genes involved in differentiation of hscs 0.5274858883966057 3.3630918980455777 0.0007707470157456 0.6654211677859521 0.0204879828036633 42 P49720,P25787,Q13951,O00487,P48556,Q13200,O00233,Q9UNM6,Q9UL46,P20618,P25788,P17980,O75832,P28072,P28074,P61289,P28066,P62333,P25789,Q06323 20
C type lectin receptors clrs 0.4661105948713712 3.3304771435828897 0.0008669728094452 0.7081850363702258 0.0208125329287224 62 P49720,P25787,P17612,O00487,P48556,Q13200,O00233,Q9UNM6,Q9UL46,P63208,P20618,O95999,P25788,P61081,Q15750,O75832,P28072,P28074,P61289,P28066,P62333,Q13404,P25789,Q8TBC4,Q06323,P49427,Q9UDY8 27
Auf1 hnrnp d0 binds and destabilizes mrna 0.5238656263587732 3.327325631468891 0.0008768384517652 0.7122481497217912 0.0208125329287224 42 P25788,P62333,O00233,P49720,P25787,P28074,P25789,Q9UNM6,O75832,Q9UL46,P28072,P20618,O00487,Q06323,P48556,P61289,P28066,Q13200 18
Switching of origins to a post replicative state 0.4621995136523774 3.323953458463469 0.000887510060723 0.7165795701566477 0.0208125329287224 64 P49720,Q9UBD5,P25787,Q9UJX4,Q9UJX6,Q13042,O00487,P48556,P28070,Q13200,O00233,O43913,Q9UNM6,P62191,Q9UL46,P63208,Q99741,P20618,P25788,Q96DE5,P17980,O75832,P28072,P28074,P61289,P28066,P25786,O43929,P62333,P25789,Q06323,Q13309,P24941 33
Abc transporter disorders 0.5303300663879295 3.321902431097815 0.0008940595131352 0.7192055523253951 0.0208125329287224 41 P49720,P25787,O00487,P48556,Q13200,O75477,O00233,Q9UNM6,Q9UL46,P20618,P25788,O75832,P28072,P28074,P61289,P28066,P62333,P25789,Q06323 19
Defective cftr causes cystic fibrosis 0.5303300663879295 3.321902431097815 0.0008940595131352 0.7192055523253951 0.0208125329287224 41 P49720,P25787,O00487,P48556,Q13200,O75477,O00233,Q9UNM6,Q9UL46,P20618,P25788,O75832,P28072,P28074,P61289,P28066,P62333,P25789,Q06323 19
Degradation of dvl 0.5482692068619686 3.3081768273640777 0.0009390549661789 0.7366008033000078 0.0212585770291392 38 P25788,P62333,O00233,P49720,P25787,P28074,P25789,Q9UNM6,O75832,Q9UL46,P28072,P20618,O00487,Q06323,P48556,P61289,P28066,Q13200 18
Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1 0.4790202480686293 3.3069544649192943 0.0009431622203068 0.7381339941955726 0.0212585770291392 51 P49720,P25787,Q9UJX4,Q13042,Q9UJX6,O00487,P48556,Q13200,O00233,Q9UNM6,P62191,Q9UL46,P20618,P25788,O14965,Q96DE5,P17980,O75832,P28072,P28074,P61289,P28066,P25786,P62333,P25789,Q06323,Q13309 27
Cross presentation of soluble exogenous antigens endosomes 0.5522487711117091 3.290639899973367 0.0009995978310204 0.7583195360458261 0.0212646707238057 37 P25788,P62333,O00233,P49720,P25787,P28074,P25789,Q9UNM6,O75832,Q9UL46,P28072,P20618,O00487,Q06323,P48556,P61289,P28066,Q13200 18
Degradation of axin 0.5522487711117091 3.290639899973367 0.0009995978310204 0.7583195360458261 0.0212646707238057 37 P25788,P62333,O00233,P49720,P25787,P28074,P25789,Q9UNM6,O75832,Q9UL46,P28072,P20618,O00487,Q06323,P48556,P61289,P28066,Q13200 18
Mapk family signaling cascades 0.4005486053850505 3.2904726490067584 0.0010001922468465 0.7585236493261007 0.0212646707238057 96 P49720,P25787,P36873,P17612,O00487,P48556,Q13557,Q13200,P62140,P31946,Q13362,O00233,Q9UNM6,P62191,Q9UL46,P20618,P25788,Q92796,P17980,O75832,P28072,P28074,P61289,P36404,P28066,P62333,Q99956,P25789,P53041,O75608,P06493,Q06323,P49356,Q16181,Q13555 35
Transcriptional regulation by runx3 0.4895595586740678 3.2890205602311093 0.0010053667922098 0.7602932475676414 0.0212646707238057 46 P49720,P25787,Q13951,O00487,P48556,Q13200,O00233,Q9UNM6,P25440,P62191,Q9UL46,P20618,P25788,P42771,P17980,O75832,P28072,P28074,P61289,Q13485,P28066,P62333,P25789,Q06323 24
Regulation of ras by gaps 0.5327002808417337 3.2800911431774775 0.0010377355595572 0.7710724313269639 0.0213562970227717 40 P25788,P62333,O00233,P49720,P25787,P28074,P25789,Q9UNM6,O75832,Q9UL46,P28072,P20618,O00487,Q06323,P48556,P61289,P28066,Q13200 18
Transcriptional regulation by runx2 0.4695549139498672 3.2668354269414097 0.0010875688373919 0.7867282597847496 0.0220621107013789 56 P49720,P25787,P11802,Q13951,O00487,P48556,Q13200,O00233,Q9UNE7,Q9UNM6,Q9UL46,P63208,P20618,P25788,P17980,O75832,P28072,P28074,P61289,Q13485,P28066,P62333,P25789,P06493,Q06323 25
Interleukin 1 family signaling 0.4669819613509643 3.2368828032860772 0.0012084302897075 0.8203974029618571 0.023832930713676 56 P49720,P25787,P09429,P43378,O00487,P48556,Q13200,O00233,Q9H3S7,Q9UNM6,P52564,P62191,Q9UL46,P63208,P20618,P51617,P25788,Q15750,P17980,O75832,P28072,P28074,P61289,P28066,P62333,Q13404,P25789,Q06323 28
Dna replication pre initiation 0.4520463755864226 3.220568270932421 0.0012793671658295 0.8376278703853118 0.0246573158505549 65 P49720,P35244,P25787,Q9UBD5,O00487,P48556,Q13200,O00233,O43913,Q9UNM6,P62191,Q9UL46,Q99741,P20618,Q9NR33,P25788,P17980,P16104,O75832,P28072,P28074,P61289,P28066,P25786,O43929,P62333,P25789,P15927,Q06323,P24941 30
Mapk6 mapk4 signaling 0.4691522934112728 3.207300583203555 0.0013398691818322 0.8510120732725079 0.0253681898426909 52 P49720,P25787,P17612,O00487,P48556,Q13200,O00233,Q9UNM6,P62191,Q9UL46,P20618,P25788,P17980,O75832,P28072,P28074,P61289,P28066,P62333,P25789,P06493,Q06323,Q16181 23
The role of gtse1 in g2 m progression after g2 checkpoint 0.4693935167519212 3.1980942495944817 0.0013833905887765 0.859952645462647 0.0258475610008253 51 P49720,P25787,O00487,P48556,Q13200,O00233,P04350,Q9BUF5,Q9UNM6,P62191,Q9UL46,P20618,P25788,Q9BVA1,P17980,O75832,P28072,P28074,O95067,P61289,P28066,P62333,P25789,P06493,Q06323,Q15691 26
Asymmetric localization of pcp proteins 0.5340991234771234 3.1766579354796662 0.0014898264448253 0.8796235089740031 0.0264585132730551 38 P25788,P62333,O00233,P49720,P25787,P28074,P25789,Q9UNM6,O75832,Q9UL46,P28072,P20618,O00487,Q06323,P48556,P61289,P28066,Q13200 18
Signaling by hedgehog 0.4585713345783416 3.169067129708558 0.0015292906916128 0.8861934242163043 0.0268097874332137 58 P49720,P25787,P17612,O00487,P48556,P28070,Q13200,O00233,P04350,Q9BUF5,Q9UNM6,P62191,Q9UL46,P63208,P20618,P49407,P25788,Q9BVA1,Q8NCM8,P17980,O75832,P28072,P28074,P61289,P28066,P25786,P62333,P25789,Q06323 29
Pcp ce pathway 0.4646123451263191 3.143629747133146 0.0016686642304704 0.9066577433319826 0.0288963805764387 51 P49720,P25787,O00487,P48556,P09497,Q13200,O00233,Q9UNM6,Q9UL46,P20618,P25788,P61586,P07737,O75832,P28072,P28074,P61289,P28066,P62333,P25789,Q06323 21
Cellular response to chemical stress 0.4205419349384721 3.0909854170498265 0.0019949343130651 0.9413188143065016 0.0337238895780067 76 P49720,P25787,P30048,P19784,O00487,P48556,Q13200,P30041,Q16881,P04179,O00233,Q9UNM6,P30044,Q9UL46,Q86X55,P20618,P63208,P00390,P25788,P67870,O75832,P28072,P28074,P30519,P61289,P28066,P62333,P00403,P25789,Q8TCT9,Q06323 31
Tcf dependent signaling in response to wnt 0.4390817488388667 3.0591012541259346 0.0022200210279392 0.9574014165032974 0.035823066587202 65 P49720,P25787,P19784,O00487,P48556,Q13200,Q13362,O00233,Q9UNM6,Q9UL46,P20618,P25788,Q13363,Q70CQ2,P17980,P67870,O75832,P28072,P28074,P61289,P28066,P62333,P25789,Q06323,Q92993 25
Base excision repair 0.5509162643188543 3.030732174107704 0.0024396154249228 0.9688358384412408 0.0376980926140672 31 Q9UGN5,P27695,Q15054,P12004,P35244,Q96T60,P39748,P15927,P16104,P18887,P78549,P40937,P29372,P18858,Q9NR33 15
Hedgehog on state 0.4869110079568914 3.023642988975439 0.002497509734328 0.9713011972840092 0.0376980926140672 43 P49720,P25787,O00487,P48556,Q13200,O00233,Q9UNM6,P62191,Q9UL46,P20618,P49407,P25788,P17980,O75832,P28072,P28074,P61289,P28066,P62333,P25789,Q06323 21
Pcna dependent long patch base excision repair 0.6366607276776572 3.0206826429151397 0.0025220554917861 0.9722866920127738 0.0376980926140672 19 P27695,Q15054,P35244,P39748,P15927,P40937,P18858,Q9NR33 8
Resolution of ap sites via the multiple nucleotide patch replacement pathway 0.5924874500192717 2.967171602964133 0.0030055316068939 0.9860779497663552 0.0413190346060572 23 Q9UGN5,P27695,Q15054,P35244,P39748,P15927,P40937,P18858,Q9NR33 9
Hedgehog ligand biogenesis 0.5059442345302304 2.963394127483253 0.0030426671018115 0.9867951844634888 0.0413190346060572 39 P25788,P62333,O00233,P49720,P25787,P28074,P25789,Q9UNM6,O75832,Q9UL46,P28072,P20618,O00487,Q06323,P48556,P61289,P28066,Q13200 18
Fc epsilon receptor fceri signaling 0.4310726980502854 2.9019761544014893 0.0037081676538071 0.9948840139951144 0.0465982129947441 62 P49720,P25787,O00487,P48556,P28070,Q13200,O00233,P07948,Q9UNM6,P62191,Q9UL46,P63208,P20618,O95999,P25788,Q15750,P17980,O75832,P28072,P28074,P61289,P28066,P25786,P62333,Q13404,P25789,Q06323,P49427,Q9UDY8 29
Regulation of mrna stability by proteins that bind au rich elements 0.4212077912684603 2.8732536977897087 0.004062677261402 0.9969136074944868 0.0502012001607799 67 P49720,O14818,P25787,O00487,P48556,P28070,Q13200,P31946,Q96B26,Q9Y3B2,O00233,Q9UNM6,P62191,Q9UL46,P20618,P25788,O43242,P39687,Q15717,Q13868,Q9Y2L1,Q16539,P17980,O75832,P28072,P28074,Q9NPD3,P61289,P28066,P25786,P62333,P25789,Q9NQT4,Q01105,Q06323,O00231,Q5RKV6,Q9NQT5 38
Metabolism of water soluble vitamins and cofactors 0.4588956884408518 2.8730272745420327 0.0040655901538659 0.996926399276163 0.0502012001607799 45 P05165,Q9Y4U1,O96007,Q96CD2,P78417,P00374,Q9UKK3,Q9H3L0,Q96EN8,P49914,Q9NZB8,P50747,Q96RQ3,Q9H2D1,P34896,Q8IXQ6,Q8NFF5,P00387 18
Mitotic g2 g2 m phases 0.3760442188575805 2.864152952588388 0.0041812605761155 0.9973937362987854 0.0505825270848159 99 P49720,P25787,P30307,P07437,P17612,O00487,P48556,P62258,P28070,P20248,Q13200,P62140,P30153,O00233,P04350,Q9BUF5,Q9UNM6,P61163,P62191,Q9UL46,P63208,P20618,P61006,P25788,O14965,Q9BVA1,P17980,O75832,P28072,P28074,O95067,Q9H6D7,P61289,Q5TKA1,P63151,P28066,P25786,P62333,P61981,P25789,P06493,Q06323,Q9Y570,P24941,Q15691,P63167 46
Global genome nucleotide excision repair gg ner 0.4630828340973094 2.8435244039970606 0.0044617592409244 0.9982530336075894 0.0525026180918057 44 Q13098,Q9UGN5,Q15054,Q9BT78,P12004,P35244,Q9UBW8,Q9UNS2,Q92905,P15927,P18887,P32780,P40937,P18858,Q9NR33,Q7L5N1 16
Uch proteinases 0.4392061271877827 2.8400399584101224 0.0045107883149297 0.9983710335061876 0.0525026180918057 50 Q9Y5K5,P49720,P25787,O00487,P48556,Q13200,O00233,Q9UNM6,Q9UL46,P20618,P25788,P17980,O75832,P28072,P28074,P61289,P28066,P62333,P25789,Q06323 20
Interconversion of nucleotide di and triphosphates 0.6361921463041156 2.772187088605991 0.0055681024109961 0.9996397816388656 0.0612922901055389 17 Q16881,P32321,Q9H773,P54819,P00390,Q9NRF8,P35754,P33316,P15531 9
Signaling by the b cell receptor bcr 0.4299567968763335 2.76127740987964 0.0057575748570972 0.9997251769974604 0.0613965525144299 53 P49720,P25787,O00487,P48556,Q13200,O00233,P07948,Q9UNM6,P62191,Q9UL46,P63208,P20618,O95999,P25788,P17980,O75832,P28072,P28074,P61289,P28066,P62333,P25789,Q06323,Q9UDY8 24
Metabolism of folate and pterines 0.7842586699856897 2.7602182021025135 0.0057762766848592 0.9997324205237575 0.0613965525144299 9 P00374,P34896,P49914 3
Gap filling dna repair synthesis and ligation in gg ner 0.5941643747394851 2.726699664274995 0.0063971236426358 0.9998897869833644 0.0667934968569336 19 Q15054,P35244,P15927,P18887,P40937,P18858,Q9NR33 7
Dna strand elongation 0.510294579886846 2.651870327023604 0.0080047277737373 0.9999889430504108 0.0794875065643853 30 Q15054,P35244,P39748,Q9Y248,P15927,Q9BRT9,P40937,Q9BRX5,P18858 9
Antigen processing cross presentation 0.4202942430530222 2.635421349878792 0.0084032897767591 0.9999937510117646 0.0817306265958771 52 P49720,P25787,P09429,O00487,P48556,Q13200,O00233,Q9UNM6,P62191,Q9UL46,P20618,P25788,P60059,P17980,P04439,O75832,P28072,P28074,P61289,P28066,P25786,P62333,P25789,Q06323 24
Dual incision in gg ner 0.5240603967314277 2.5268328750282465 0.0115096258479197 0.9999999274109272 0.1089577913603065 25 Q9UGN5,P35251,Q15054,P12004,P35244,P35250,P15927,P32780,Q92889,P18074,P40937,Q9NR33,P19447 13
Signaling by wnt 0.3512894460846851 2.4999166382605513 0.0124222533353257 0.9999999804458324 0.1168185412990899 97 P49720,P25787,P19784,O00487,P48556,P09497,Q96QK1,Q13200,Q13362,O00233,Q9UNM6,Q9UBQ0,Q9UL46,P63208,P20618,P25788,P61586,Q13363,Q9Y3A6,Q70CQ2,P17980,P67870,P07737,O75832,P16104,P28072,P28074,P61289,P28066,P62333,P25789,Q06323,Q92993 33
Transcription coupled nucleotide excision repair tc ner 0.4100044577749367 2.4870816826736304 0.0128795823430936 0.9999999898704148 0.119535992988189 49 Q13098,Q15054,Q9BT78,P12004,P35244,Q9UBW8,Q9UNS2,Q92905,P15927,P62487,P18887,P19387,P32780,P40937,O15514,P18858,Q9NR33,Q7L5N1 18
Polb dependent long patch base excision repair 0.753818108788334 2.371133904106258 0.0177336050801133 0.9999999999907618 0.1564081938742916 7 P18858,Q9UGN5,P27695 3
G2 m checkpoints 0.3415959671267735 2.342429058583802 0.0191586758339497 0.9999999999988244 0.1666339143783252 97 Q9NXR7,Q8N2W9,P49720,P35244,P25787,Q9UBD5,P30307,P40937,O00487,P48556,P62258,Q13200,P31946,O00233,Q9UNM6,O96017,Q9UL46,P20618,Q99741,P38398,P25788,Q9UQ84,P17980,P16104,O75832,P28072,P28074,O95067,P61289,P28066,O43929,P62333,P25789,P15927,P06493,Q06323,P24941,Q92993 38
Signaling by notch 0.3880846713399871 2.3407501039898375 0.0192450436324262 0.9999999999989626 0.1666339143783252 61 P49720,P25787,Q9Y6A5,O00487,P48556,P67809,Q13200,O00233,Q04721,Q9UNM6,P62191,Q9UL46,P63208,P20618,P49407,P25788,P17980,P16104,O75832,P28072,P28074,P61289,P28066,P25786,P62333,P25789,Q06323 27
Cytoprotection by hmox1 0.3802841963700078 2.334073220224821 0.019591888271879 0.9999999999993724 0.1686089778549593 67 P49720,P25787,P19784,O00487,P48556,Q13200,O00233,Q9UNM6,Q9UL46,Q86X55,P20618,P63208,P25788,P17980,P67870,O75832,P28072,P28074,P30519,P61289,P28066,P62333,P00403,P25789,Q8TCT9,Q06323 26
Cyclin d associated events in g1 0.6282193207687119 2.3105018691356185 0.02086038517634 0.9999999999999002 0.1743317835562264 13 P42771,P30153,P11802,P07948,P06400,P63208,Q13309,P24941,P63151 9
Dna damage recognition in gg ner 0.5468777485569203 2.2744701852611415 0.0229377317381151 0.9999999999999952 0.1819641288721987 18 Q9UGN5,Q9BT78,Q9UBW8,Q9UNS2,Q92905,Q7L5N1 6
Mismatch repair 0.6186484971072445 2.252814972708879 0.0242708177360637 0.9999999999999992 0.1914697843622808 13 Q15054,Q9UQ84,P35244,P15927,P18858 5
Lagging strand synthesis 0.5061950932619983 2.233399240662971 0.0255226282199256 1.0 0.1988674749833253 21 Q15054,P12004,P35244,P39748,P35250,P15927,P49643,P40937,P18858 9
Tgf beta receptor signaling activates smads 0.6303327918557673 2.2333661552708364 0.0255248081686803 1.0 0.1988674749833253 12 P62140,P61081,P62136,Q9Y5K5,Q9UNE7,P36873,Q9Y3F4 7
Downregulation of tgf beta receptor signaling 0.6821855362517186 2.231792266151636 0.025628695719682 1.0 0.1988674749833253 9 P62140,P62136,Q9Y5K5,Q9UNE7,P36873 5
Copi independent golgi to er retrograde traffic 0.4596345878146823 2.180830973982867 0.0291959206889562 1.0 0.218201091464831 29 Q96FJ2,P47755,Q13561,Q9BVA1,Q9BUF5,Q8TD16,P04350,Q15042,P68371,Q9NZ32,P61163,P68402,P52907,Q9Y6G9,P63167,Q9UJW0,O75935 17
Activation of ampk downstream of nmdars 0.6860485281015707 2.1386237911937744 0.0324661491071518 1.0 0.2388701126018425 8 P04350,Q9BUF5,Q13131 3
Chk1 chk2 cds1 mediated inactivation of cyclin b cdk1 complex 0.6247001222145149 2.11926639948901 0.0340679595780324 1.0 0.2493634154680724 11 P31946,Q9Y3B8,P61981,P30307,O96017,P06493,P14635,P62258 8
Antigen processing ubiquitination proteasome degradation 0.3313421888825048 2.111625684812255 0.0347185677299692 1.0 0.2517842048116725 101 Q9BSL1,Q5GLZ8,Q9Y508,P49720,P25787,O95352,Q13042,O00487,P48556,Q15369,Q13200,O00233,Q9UNE7,Q9UNM6,Q9UL46,P63208,P20618,Q15370,P25788,P61081,Q9H2C0,P17980,O75832,P28072,P28074,P61289,P28066,P62333,Q05086,Q13404,P25789,Q8TDB6,Q8TBC4,Q06323,Q13309,P49427,O94822,Q63HN8 38
Triglyceride metabolism 0.6411086369686292 2.1076144221831616 0.0350643550542746 1.0 0.2517842048116725 10 P62140,Q01469,P62136,P36873,P17612 5
Rho gtpases activate pkns 0.491689362069713 2.0927688041438333 0.0363697978658228 1.0 0.2548456615282485 20 P62140,P31946,P61586,P30307,P16104,Q7Z406,P62258,P60660 8
Intraflagellar transport 0.5904263935706834 2.080734937434794 0.0374581743300406 1.0 0.2548456615282485 13 Q96FJ2,Q9BVA1,A0AVF1,Q9BUF5,P04350,Q9BW83,Q96EX3,P63167 8
Dna damage reversal 0.7490252772524806 2.0524014936621997 0.0401306594971058 1.0 0.2675377299807054 6 P16455,Q8N9N2 2
Detoxification of reactive oxygen species 0.6434689579411556 2.0231389779865774 0.0430588209011408 1.0 0.2754212868451353 9 Q16881,P04179,P30048,P30044,P00390 5
Triglyceride catabolism 0.6427324241865701 2.0191271801069957 0.0434740025046758 1.0 0.2762934465201729 9 P62140,Q01469,P62136,P36873,P17612 5
Metabolism of nucleotides 0.3779465589458702 2.0180666699822276 0.0435843183243089 1.0 0.2762934465201729 46 Q9UKK9,P04183,Q9P2T1,Q9NRF8,P00492,Q16881,O43598,P49915,P49902,P00390,P07741,Q9H0P0,P20839,Q96DE0,P00491,Q9BY32,P33316,P55263,Q9H773,P54819,P35754,P32321,P15531 23
Metabolism of cofactors 0.7410784027770565 2.015327751275136 0.0438703190291782 1.0 0.2768704578730361 6 P00374 1
Maturation of sars cov 2 nucleoprotein 0.6816649221342623 2.01029317663454 0.0444001686379107 1.0 0.2777896303453905 7 Q96SB4,Q9UKK3,P49840,Q8IXQ6,Q99873 5
Regulation of tp53 activity through phosphorylation 0.4007249841059234 1.98561596019996 0.0470759829086495 1.0 0.284459130767159 41 Q96S44,O14965,Q13131,P40937,P35244,Q9UQ84,P54619,Q16539,P15927,P67870,O96017,P19784,P38398,P24941,Q92993 15
Nucleotide salvage 0.6560288134535831 1.9812856942744417 0.0475592437642116 1.0 0.2846547248646149 8 P55263,P04183,Q9P2T1,P00491,P07741 5
Processive synthesis on the lagging strand 0.5452208845577625 1.9807977943579045 0.0476139542712488 1.0 0.2846547248646149 15 Q15054,P35244,P39748,P15927,P18858 5
Mrna decay by 3 to 5 exoribonuclease 0.5313331092964031 1.9712392256441291 0.048696519166852 1.0 0.2857399058550821 16 Q96B26,Q9Y3B2,Q9Y450,Q9GZS3,Q96C86,Q969T7,Q13868,Q9Y2L1,Q9NPD3,Q5RKV6,Q9NQT5 11
Translesion synthesis by polk 0.6156615029467355 1.964641105549118 0.0494557908515087 1.0 0.2890009177330964 10 P12004,P35244,P35250,P15927,P40937 5
Gene and protein expression by jak stat signaling after interleukin 12 stimulation 0.4560173167102337 1.924975456516215 0.0542324288223607 1.0 0.313048979381107 24 P52597,P04179,P05388,Q99439,P14174,Q9UL46,Q00169,P23528,Q13126 9
Apoptotic factor mediated response 0.6244841498496849 1.9192432686468397 0.0549535539715273 1.0 0.3147772411294166 9 Q96GX9,Q07021,P42771,Q16611 4
Intrinsic pathway for apoptosis 0.4593117412180822 1.9190723344258485 0.0549751801409121 1.0 0.3147772411294166 23 Q96FJ2,P31946,P42771,P61981,Q96GX9,Q07021,Q16611,P30419,P62258,P63167 10
Metabolism of amino acids and derivatives 0.3879805842155066 1.8960455136673928 0.0579540264346891 1.0 0.325812046404119 199 P62841,Q13126,P63220,Q9Y3U8,P61513,Q9UL46,Q14353,P00390,Q96I15,P16930,Q96GX9,Q9BV57,O75832,P34896,P28066,O43324,P12277,P61927,P62888,P62854,Q06323,P52788,P26373,P49720,P25787,P62847,O00487,O43708,Q16881,P78330,P21953,Q07020,P61313,P20618,P08708,P32969,P62899,P25325,P28072,P28074,P61289,P62333,P61254,P17174,P48556,P62913,Q13200,Q12904,P19623,P62081,O00233,Q9UNM6,P42766,P46778,P17980,P46776,P62857,P63173,Q99714,P62906,P62273,P62249,P62753,P25789,P05386,P08865,P18621,P62191,P57772,P05388,P62244,Q6NVY1,P50914,P46777,P25788,P62910,P84098,P61457,P25786,P30050,P60866,Q96RQ3,P62829 83
Cooperation of prefoldin and tric cct in actin and tubulin folding 0.5076324745650956 1.895323089089786 0.0580496110846775 1.0 0.325812046404119 17 Q9NQP4,P04350,Q9BUF5,Q9UHV9 4
Ub specific processing proteases 0.3148197754118851 1.8932390564433448 0.0583260856399672 1.0 0.3260749669635962 88 Q9NZL9,P49720,Q9UPT9,P25787,Q14318,Q9Y5T5,O00487,P48556,Q13200,O00233,Q9UNM6,P62191,Q9UL46,P20618,P25788,Q9Y277,Q96FW1,Q15750,Q70CQ2,P17980,O75832,P28072,P28074,O60493,P61289,Q13485,P28066,P62333,P25789,Q06323,P54578,Q13309 32
Transcriptional regulation by runx1 0.3322589450498843 1.8607560250329152 0.0627786381259092 1.0 0.3436294797953941 77 P49720,P25787,Q15723,Q13951,P19784,O00487,P48556,Q99873,Q13200,O00233,Q9UNM6,Q9UL46,P20618,P25788,Q16625,Q92925,P17980,Q12824,P67870,O75832,P28072,P28074,P61289,P28066,O00257,P62333,P25789,Q06323 28
Ephrin signaling 0.63314904409658 1.8597699981509128 0.0629180737653538 1.0 0.3436294797953941 8 O00560,Q9Y2X7 2
Termination of translesion dna synthesis 0.4599673063570129 1.843521853314103 0.0652528540326684 1.0 0.3539940760982745 20 Q15054,P35244,P15927,Q15004,P40937,Q9NR33 6
Activation of nmda receptors and postsynaptic events 0.4218111135342527 1.835408900554932 0.0664451259229461 1.0 0.357394237918877 29 P10644,Q92796,Q9BVA1,Q13131,P04350,Q9BUF5,P54619,Q13555,P17612,Q9Y2X7,Q15418,Q13557 12
Pten regulation 0.3390797416609811 1.8199395776021312 0.0687682069160893 1.0 0.3671084730107024 70 P49720,P25787,P19784,O00487,P48556,O00233,Q9UNE7,Q9UNM6,Q9UL46,P20618,P25788,P67870,O75832,P28072,P28074,P61289,P28066,P62333,O00257,P25789,Q06323 21
Unwinding of dna 0.6043364241429848 1.807911994481722 0.0706201986616994 1.0 0.3741816496254224 9 Q9Y248,Q9BRX5 2
Metabolism of vitamins and cofactors 0.3509280892100462 1.797963302400903 0.0721828234126009 1.0 0.3776558810648339 55 Q9Y4U1,O96007,Q96CD2,P00374,Q5T2R2,Q96EN8,P49914,P50747,Q96RQ3,Q86YH6,P34896,Q9H2D1,Q8NFF5 13
Transport to the golgi and subsequent modification 0.3196380791356897 1.766794808403836 0.0772625984905954 1.0 0.394650682937574 81 P54920,P47755,Q16706,P56962,Q9Y296,P83436,P33908,P04350,Q9UP83,P61923,Q9BUF5,O14579,Q9H0V9,P61163,O15027,P63167,P18085 17
Deadenylation dependent mrna decay 0.3663066187734638 1.7565629380205932 0.0789923348324284 1.0 0.4000112849323941 44 Q9Y450,O75175,Q96B26,Q9Y3B2,Q9GZS3,Q9UK45,Q86TB9,P60842,Q9UIV1,Q5TAX3,Q969T7,Q13868,Q9Y2L1,Q9Y333,Q9NPD3,Q14240,Q9H074,Q96F86,Q96C86,P06730,Q8IZD4,Q5RKV6,Q9NQT5 23
Gamma carboxylation hypusine formation and arylsulfatase activation 0.5508242651056966 1.755846392451346 0.0791146404682872 1.0 0.4000112849323941 12 Q9BU89,P49366,P63241,Q9HA64 4
Phenylalanine and tyrosine metabolism 0.7971017755937965 1.7555974806369226 0.0791571627225371 1.0 0.4000112849323941 4 P61457,P16930 2
Purine salvage 0.6312665186666139 1.7504914886533989 0.0800335415462707 1.0 0.4015817279000157 7 P07741,P00491,P55263,Q9P2T1 4
Intra golgi traffic 0.5371556736499632 1.748379115322575 0.0803984018271632 1.0 0.4019920091358164 13 P54920,Q16706,P33908,P83436 4
Rho gtpases activate rocks 0.5728027364820181 1.719639053500107 0.0854980726258425 1.0 0.416446009880164 10 P62140,Q7Z406,P61586,P60660 4
Methionine salvage pathway 0.7292374931962761 1.715052721835299 0.0863355612569232 1.0 0.4169948877035067 5 Q96GX9,Q9BV57,Q13126 3
Nucleotide excision repair 0.3412280369720575 1.705206500640212 0.0881559180543893 1.0 0.4243437411431624 59 P12004,P35244,Q9UBW8,Q9UNS2,P62487,P19387,P40937,O15514,Q9BT78,Q92905,Q9NR33,Q9UGN5,Q15054,P18887,P32780,Q7L5N1,Q13098,P15927,P18858 19
Copi mediated anterograde transport 0.3437632611015968 1.699218120329557 0.0892780934111252 1.0 0.4282935562290468 54 Q96FJ2,Q9Y3B3,Q9UP83,P54920,P62820,P04350,Q9BUF5,P61923,P61163,P84085,P52907,P48444,P47755,Q9BVA1,P83436,Q8N6T3,P18085,O14579,P63167 19
Interleukin 12 signaling 0.4197418512000379 1.6855440162023023 0.0918836600333175 1.0 0.4378348900916471 26 P52597,P04179,P05388,Q99439,P14174,Q9UL46,Q00169,P23528,Q13126 9
Signaling by interleukins 0.3191597561088484 1.6453350588021065 0.0999007337483224 1.0 0.4503461648337074 119 P49720,P09429,P25787,P43378,P17612,Q00169,O00487,P48556,Q15418,Q13126,P51452,Q13200,P52597,P04179,P14174,O00233,P78417,Q9H3S7,P07948,Q9UNM6,P52564,P62191,Q9UL46,P63208,P20618,P05388,P52907,P51617,P23528,P25788,Q99439,Q15750,Q16539,P17980,O75832,P28072,P28074,P61289,P28066,P62333,Q13404,P25789,P04083,Q06323 44
Tbc rabgaps 0.4342897078998793 1.6384385295167507 0.1013302472367509 1.0 0.4539083630163609 20 P60520,Q15276,P62330,Q15286,Q92930,Q9UJ41,P61006 7
Recycling of eif2 gdp 0.5913098756194555 1.6343274365095632 0.1021901156811528 1.0 0.4548901701167306 8 P05198,P49770,P20042,Q9NR50,Q14232,Q13144 6
Beta catenin independent wnt signaling 0.3316016709517012 1.629528410246263 0.1032012056290716 1.0 0.4565286977983854 64 P49720,P25787,O00487,P48556,P09497,O00233,Q9UNM6,Q9UL46,P20618,P25788,P61586,P07737,O75832,P28072,P28074,P61289,P28066,P62333,P25789,Q06323 20
Cilium assembly 0.3302728446561139 1.6236751804484004 0.1044451507863712 1.0 0.460596627691451 65 A0AVF1,P36405,P04350,Q8IYI6,Q9BUF5,P61163,Q96EX3,Q9BW83,P06493,P07437,P17612,Q15051,Q9H6D7,P62258,P63167,P18085 16
Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand 0.391466866831413 1.616633947490257 0.1059573195526022 1.0 0.4635219032945461 33 Q96FJ2,P54652,P68371,Q15185,P04350,Q9BUF5,P61163,Q13451,P52907,Q9UJW0,O75935,P47755,Q9BVA1,Q9NZ32,O60884,Q13561,P31689,Q9Y6G9,P63167,P31948 20
Translesion synthesis by polh 0.5156798270456658 1.6119742735641542 0.1069675381013885 1.0 0.4659322211778276 13 Q8TAT6,P12004,P35244,P35250,P15927,P40937 6
Wnt ligand biogenesis and trafficking 0.7601123595505661 1.5994467698487111 0.1097213672273114 1.0 0.4735694269385477 4 Q9UBQ0,Q9Y3A6,Q96QK1 3
Glutathione conjugation 0.4863437156103418 1.5844672359032872 0.113087431898009 1.0 0.482493414271069 15 P28161,O75223,P78417,Q8WUX2,P21266,P10768,Q96KP4,O43708 8
Rab geranylgeranylation 0.4275484230295426 1.5842004827322422 0.1131481034875112 1.0 0.482493414271069 20 P62820,Q92696,Q15286,P61026,P51148,Q92930,Q969Q5,P61006 8
Trna modification in the nucleus and cytosol 0.4512656421209336 1.574313645738903 0.1154149565889675 1.0 0.4899051825634767 18 Q96S44,Q96FX7,Q9NPF4,Q9UET6,Q9UJA5,Q9UI30,Q96PZ0,Q9UBP6 8
Synthesis of dolichyl phosphate 0.9090398652442484 1.5488285046761243 0.1214229513463689 1.0 0.5012500788665774 2 P53602 1
Molybdenum cofactor biosynthesis 0.6432243091242779 1.5488008691191468 0.1214295965704947 1.0 0.5012500788665774 6 O95396,Q96EN8,O96007,Q9NZB8 4
Recognition of dna damage by pcna containing replication complex 0.4337842033791429 1.533388709343982 0.1251801089850679 1.0 0.5040839641929865 19 Q15054,P35244,P15927,P40937,Q9NR33 5
Signaling by mras complex mutants 0.6873019553588897 1.5257549165136584 0.1270709122577107 1.0 0.5040839641929865 5 P62140,P36873 2
Synaptic adhesion like molecules 0.5704510968246421 1.5206105877401976 0.1283575882641172 1.0 0.5052641204730784 8 Q92796 1
Hdr through homologous recombination hrr 0.3867108046002208 1.5200316732122965 0.1285030154240516 1.0 0.5052641204730784 30 Q15054,P35244,Q9UQ84,Q96B01,Q92993,P15927,P40937,P38398,Q9NR33 9
Branched chain amino acid catabolism 0.476318360708375 1.5160037335379564 0.1295184083466201 1.0 0.5052641204730784 15 Q6NVY1,Q99714,P21953 3
Sema4d induced cell migration and growth cone collapse 0.5846388596350715 1.505393147594844 0.1322230297741882 1.0 0.5144019240530062 7 P61586,P60660 2
Mtor signalling 0.4726348620234311 1.4907991357329728 0.1360142387635829 1.0 0.5262676268236726 15 P62753,P54619,Q13131 3
Regulation of plk1 activity at g2 m transition 0.362002025258178 1.4827561439970862 0.1381392118888758 1.0 0.5270313881075145 39 P62140,P04350,P61163,P06493,P07437,P17612,P63208,Q9H6D7,P62258,P63167,P61006 11
Tp53 regulates transcription of genes involved in g2 cell cycle arrest 0.5462358604910232 1.4815724843782747 0.1384540849194722 1.0 0.5270313881075145 9 O14965,P12004,P30307,P06493,Q99873 5
Long term potentiation 0.6278690069998174 1.4742139750444212 0.1404239882994706 1.0 0.5289179400139215 6 Q13555,Q92796,Q13557 3
Signaling by tgf beta receptor complex 0.4020758682107208 1.4663386431450645 0.14255605281555 1.0 0.5353353020262362 24 P62140,P08047,P61081,P61586,P62136,Q9Y5K5,Q9UNE7,P36873,Q9UPN9,Q9Y3F4 10
Translesion synthesis by y family dna polymerases bypasses lesions on dna template 0.405071193509275 1.4651435900422929 0.1428817461041855 1.0 0.5353353020262362 23 Q8TAT6,Q15054,P12004,P35244,P35250,P15927,Q15004,P40937,Q9NR33 9
Autophagy 0.3229005993413006 1.455968936037029 0.1454012071444099 1.0 0.5428914081900633 58 Q13131,P04350,Q9BUF5,Q13404,P13473,Q9H9H4,O95352,P54619,P67870,P19784,P63167 11
Wnt mediated activation of dvl 0.8860190903986551 1.455022194255771 0.1456631172678972 1.0 0.5428914081900633 2 P67870 1
Eph ephrin signaling 0.367029271457545 1.443121632245841 0.148986210544805 1.0 0.5479493639298747 36 P61586,O00401,O15144,O43639,Q7Z406,O15145,O00560,Q9Y2X7,P23528,P60660 10
Homology directed repair 0.3237645466827625 1.4337785477256708 0.1516354686790419 1.0 0.5508461890874654 52 Q9NXR7,Q9UGN5,Q15054,Q8N2W9,P35244,Q9UQ84,Q96B01,P24941,P38398,P60510,Q9NR33 11
Regulation of tp53 expression and degradation 0.4638152181565574 1.4303612793944231 0.1526133553816695 1.0 0.5518752372725484 15 P24941,O96017,P42771 3
Formyl peptide receptors bind formyl peptides and many other ligands 0.8795620437956245 1.428704459310835 0.1530891955829909 1.0 0.5518752372725484 2 P04083 1
Rho gtpases activate paks 0.4975329776988204 1.4258791278915508 0.1539032351830487 1.0 0.5518752372725484 12 P62140,P35240,P60660 3
Unblocking of nmda receptors glutamate binding and activation 0.6555938373236119 1.3814413448589382 0.1671433009043705 1.0 0.5745669444272182 5 Q13555,Q92796,Q13557 3
Darpp 32 events 0.5142059018553147 1.3779436396614844 0.1682206898994984 1.0 0.5745669444272182 10 P10644,P62136,P17612 3
Displacement of dna glycosylase by apex1 0.8767200224656084 1.3740448633938007 0.1694277549673783 1.0 0.5745669444272182 3 P27695,P78549 2
Processive synthesis on the c strand of the telomere 0.4778710804585909 1.369504125607404 0.1708417460767206 1.0 0.5762358181210055 13 Q15054,P35244,P39748,P15927,P18858 5
Signaling by tgfb family members 0.3870881974030213 1.365249876512115 0.1721745269510224 1.0 0.5771574508610435 25 P62140,P08047,P61081,P61586,P62136,Q9Y5K5,Q9UNE7,P36873,Q9UPN9,Q9Y3F4 10
Metabolism of nitric oxide nos3 activation and regulation 0.5416217757002726 1.362410873532886 0.1730682540732115 1.0 0.5771574508610435 8 O95865,O75608,O94760 3
Endosomal sorting complex required for transport escrt 0.5102827608853 1.3548902296829144 0.1754525329786067 1.0 0.5776564800225684 10 Q9NP79,Q9H9H4 2
Raf independent mapk1 3 activation 0.6033732067995738 1.354759587263623 0.1754941661545843 1.0 0.5776564800225684 6 Q99956 1
Activation of atr in response to replication stress 0.389002650833339 1.3539957111045895 0.1757377460350349 1.0 0.5776564800225684 24 O43929,P35244,Q9UBD5,Q99741,P30307,P15927,P40937,P24941 8
Raf activation 0.4522863361990391 1.3512210100732014 0.1766246462766765 1.0 0.5778963080941951 15 P62140,P31946,Q13362,P36873,Q13557,Q13555 6
Ubiquinol biosynthesis 0.860190903986531 1.3497889363950777 0.1770836946870817 1.0 0.5780663136911635 2 Q5T2R2 1
Methylation 0.5223289171010199 1.3456519538363048 0.1784147880767195 1.0 0.5788169357402428 9 P51580,Q9NZL9,P78417,Q9HBK9,Q9UI30 5
Early phase of hiv life cycle 0.5189804249063841 1.3265738646780278 0.1846496860400988 1.0 0.5932184483641183 9 P18858,P39748,P17096 3
Ptk6 regulates cell cycle 0.8534531162268424 1.32236744810197 0.1860458229314576 1.0 0.5950114156816889 2 P24941 1
Mrna decay by 5 to 3 exoribonuclease 0.489042755989398 1.3115162089770247 0.1896834211681526 1.0 0.6009985318004357 11 Q86TB9 1
Enos activation 0.640260296254921 1.3114485412247017 0.1897062682950481 1.0 0.6009985318004357 5 O75608,O95865 2
Fanconi anemia pathway 0.5160229379110335 1.3097186628234088 0.1902910276740304 1.0 0.6009985318004357 9 P15927,P35244,O15360,Q9BXW9 4
Negative regulation of nmda receptor mediated neuronal transmission 0.5936083523866319 1.3070374274040115 0.1912000005467979 1.0 0.602004436311426 6 Q13555,Q92796,Q13557 3
Receptor mediated mitophagy 0.6382561003499752 1.30229550953669 0.1928153861236641 1.0 0.6048069355224711 5 P67870 1
Interleukin 12 family signaling 0.3642545831869315 1.2975022859854533 0.1944584190770877 1.0 0.6051556589573605 29 P52597,P04179,P05388,Q99439,P14174,Q9UL46,Q00169,Q13126 8
Vxpx cargo targeting to cilium 0.5001997101781289 1.295597138876592 0.1951143153651813 1.0 0.6051556589573605 10 Q8IYI6,P18085,P61006 3
Cytosolic iron sulfur cluster assembly 0.5132934856792223 1.2941599591626889 0.1956101742686116 1.0 0.6051556589573605 9 O76071,Q9Y5Y2,P53384 3
Inositol phosphate metabolism 0.5259531284093402 1.2761360764226397 0.2019074206192179 1.0 0.6182754328477855 8 Q13572,Q96PE3 2
Butyrate response factor 1 brf1 binds and destabilizes mrna 0.4627770778956658 1.2722760756078395 0.2032750459039161 1.0 0.6207539036205609 13 P31946,Q96B26,Q9Y3B2,Q13868,Q9Y2L1,Q9NPD3,Q5RKV6,Q9NQT5 8
Nicotinate metabolism 0.5860033726812873 1.2698522191831616 0.2041372757512389 1.0 0.6215014319801029 6 Q9BQG2,Q4G0N4,Q9UKK3,P43490,Q8IXQ6 5
Activation of bad and translocation to mitochondria 0.5246811285999889 1.2691286337931924 0.2043951892497943 1.0 0.6215014319801029 8 P31946,P62258,P61981,Q9Y3B8 4
Rrna processing in the mitochondrion 0.629074871244451 1.260362061669864 0.207538781064029 1.0 0.629711686134447 5 Q8WVM0,Q99714 2
Intracellular signaling by second messengers 0.2787815645509833 1.2534471727518328 0.2100430130502624 1.0 0.6337861769022982 100 P49720,P25787,P17612,P19784,O00487,P48556,P28070,Q13557,Q13200,P19174,P10644,Q13362,P30153,O00233,Q9UNE7,Q9UNM6,P62191,Q9UL46,P20618,P51617,P25788,P17980,P67870,O75832,P28072,P28074,P61289,P28066,P25786,O00257,P62333,P25789,Q06323,P49840,Q13555,Q8TBX8 36
Activation of the pre replicative complex 0.3799911701938391 1.2529590052096595 0.210220626282382 1.0 0.6337861769022982 23 O43929,O43913,P35244,Q9UBD5,P15927,Q99741,P24941,Q9NR33 8
Apoptosis 0.2736672841012806 1.2296441845765491 0.218830376509016 1.0 0.6514447267144713 96 Q96FJ2,P49720,P09429,P25787,O00487,P48556,P62258,Q13200,P31946,P26583,O00233,Q9UNM6,Q07021,P62191,Q9UL46,P20618,P25788,P42771,Q16625,Q96GX9,P17980,O75832,P28072,P28074,P30419,P61289,P28066,P62333,P55212,P61981,P25789,Q06323,P63167,Q16611,Q9UJU6 35
Tristetraprolin ttp zfp36 binds and destabilizes mrna 0.4451464944957859 1.2263493001244117 0.2200672563821297 1.0 0.6523914489825141 14 P31946,Q96B26,Q9Y3B2,Q13868,Q9Y2L1,Q9NPD3,Q5RKV6,Q9NQT5 8
Anchoring of the basal body to the plasma membrane 0.3453613197569373 1.2216137244684693 0.2218537360822441 1.0 0.6537720211256189 36 P04350,P61163,P06493,P07437,P17612,Q15051,Q9H6D7,P62258,P63167 9
Epha mediated growth cone collapse 0.4875961298783483 1.2214540191680496 0.2219141649172875 1.0 0.6537720211256189 10 P61586,P60660 2
Assembly and cell surface presentation of nmda receptors 0.472104477508665 1.208551878357369 0.2268350534960257 1.0 0.6587030183320175 11 Q92796,Q9BVA1,Q9BUF5,P04350,Q13557,Q13555 6
Rho gtpases activate cit 0.4830611579935682 1.1947862610919715 0.2321705495264852 1.0 0.6676469537647531 10 P62140,P61586,P60660 3
Polymerase switching 0.4294740552509559 1.194542280486144 0.2322659120843577 1.0 0.6676469537647531 15 Q15054,P12004,P35250,P49643,P40937 5
Foxo mediated transcription 0.4471174463177653 1.1714527879505163 0.2414168244207311 1.0 0.6727547801790511 13 P31946,P04179,Q96EB6,Q13485 4
Nervous system development 0.3572080432010399 1.169234581330478 0.2423091319818828 1.0 0.6727547801790511 230 P62841,Q00169,Q7Z406,P60660,Q9Y3U8,P63220,P61513,Q9UL46,P23528,Q92796,O75832,P28066,O00401,O15144,P61927,P62888,P62854,Q06323,P26373,P49720,P25787,P62847,O00487,Q9Y2X7,P09497,Q15369,Q07020,P04350,P61313,P20618,P08708,O00560,A7E2V4,P32969,Q16539,O75962,P67870,P62899,O15145,P28072,P28074,P61289,P62333,P61254,O43639,O95372,Q9Y5S9,P48556,P62913,Q15418,Q13200,P62081,P61160,O00233,Q9UNM6,P42766,Q15370,P46778,P35080,P17980,P07737,P46776,P62495,P62857,P63173,P62906,P62273,P62249,P62753,P25789,P05386,P50552,P17612,P19784,P08865,P18621,Q9BUF5,P07948,P62191,P05388,P62244,P50914,P46777,P25788,P61586,Q9BVA1,P62910,P84098,P25786,P30050,P26038,P60866,P62829,P62280 94
G1 s specific transcription 0.4464962080399659 1.1674577377652309 0.243025565970238 1.0 0.6727547801790511 13 P12004,P00374,P04183,P06493,Q99741,Q5TKA1 6
Circadian clock 0.4558067206689399 1.1651030457207396 0.2439772841732366 1.0 0.6727547801790511 12 P62140,Q96EB6,P36873,P63208 4
Runx1 regulates transcription of genes involved in bcr signaling 0.8144300954520001 1.164160416310142 0.2443590083668838 1.0 0.6727547801790511 2 Q15723 1
Tyrosine catabolism 0.8135878719820404 1.1607623804687657 0.2457385456432832 1.0 0.6727547801790511 2 P16930 1
Formation of tc ner pre incision complex 0.353508990050132 1.160397179851285 0.2458871344457236 1.0 0.6727547801790511 28 Q13098,Q9BT78,Q9UBW8,Q9UNS2,Q92905,P62487,P32780,P19387,O15514,Q7L5N1 10
Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects 0.6567415730337235 1.158140928147604 0.2468065300733652 1.0 0.6739716782772667 4 P24941,P11802,P06400 3
Dna repair 0.299759330853276 1.1563948130403754 0.2475197022610946 1.0 0.6746218372567263 132 Q9NXR7,Q8N2W9,P35244,Q9UBW8,Q9UNS2,O00213,P62487,Q15004,P19387,P78549,P40937,O15514,Q04323,Q9NY27,Q9BT78,Q96T60,Q92905,O96017,P38398,P29372,P16455,Q9NR33,Q9UGN5,P27695,Q15054,Q9UQ84,Q96B01,P39748,P18887,Q9BXW9,P32780,P60510,Q6P6C2,Q7L5N1,P24941,P53041,Q8N9N2,P15927,P18858,Q92993 40
Small interfering rna sirna biogenesis 0.6557590634697132 1.153947989118834 0.2485214929352852 1.0 0.6760546359542242 4 Q15631 1
Rab gefs exchange gtp for gdp on rabs 0.3525794491121061 1.1518807133887476 0.2493700946066885 1.0 0.6761002151632157 28 Q9Y2L5,Q9Y296,Q15286,P61026,Q92930,P62258,P61006 7
Nod1 2 signaling pathway 0.4620820093360805 1.1476964106362648 0.2510939134670518 1.0 0.6767088192426616 11 Q13404,Q15750,P52564,Q16539,P42575 5
Synthesis of substrates in n glycan biosythesis 0.373298160483841 1.145268711129051 0.2520978629432169 1.0 0.6767088192426616 20 O95394,Q9Y5P6,Q13630,Q86YN1,P53602,P10619,Q9UJ70,Q8NFW8,Q96IJ6 9
Rhobtb2 gtpase cycle 0.3726971422738001 1.1404182996416368 0.2541120725275891 1.0 0.6808285716776917 20 Q15208,Q8IYB3 2
Ketone body metabolism 0.6004161135297348 1.1296146712532409 0.2586386262292781 1.0 0.6875559264703384 5 P55809,Q9BUT1 2
Negative regulation of mapk pathway 0.4393247263829396 1.1213832130769965 0.2621247785571396 1.0 0.6892910843539599 13 P31946,Q99956,P53041 3
Activated tak1 mediates p38 mapk activation 0.554397539503804 1.11543698048392 0.2646632098423669 1.0 0.6922968152097245 6 Q13404,Q16539,Q15750,P52564 4
Telomere c strand lagging strand synthesis 0.361174188892969 1.1152801197540758 0.264730401872451 1.0 0.6922968152097245 24 Q15054,P35244,P39748,P15927,P40937,P18858 6
Organelle biogenesis and maintenance 0.2679681009343721 1.1058626686574182 0.2687859650662916 1.0 0.7008130235185449 98 A0AVF1,P54619,P07437,P17612,P62258,P04179,P04350,Q8IYI6,Q9BUF5,P61163,Q96EX3,P61006,Q06546,Q9BW83,Q9H6D7,P18085,P48735,Q5XKP0,P06493,Q15051,P36405,P63167 22
Homologous dna pairing and strand exchange 0.3639579595204065 1.083343639287718 0.2786559221283982 1.0 0.7053322806102058 21 Q9UQ84,P35244,Q96B01,P15927,P38398,Q92993 6
Transcription of e2f targets under negative control by p107 rbl1 and p130 rbl2 in complex with hdac1 0.589392133126321 1.0794815593263754 0.2803731100715798 1.0 0.705871479783281 5 P06493,P20248,Q5TKA1 3
Ikk complex recruitment mediated by rip1 0.6370004460615017 1.074063896195805 0.2827940446486114 1.0 0.7064291248030504 4 Q13404,Q6SZW1 2
Nicotinamide salvaging 0.5858387187412099 1.063353014366114 0.2876218918952971 1.0 0.7090678584918781 5 Q8IXQ6,Q9BQG2,Q9UKK3,P43490 4
Regulation of bach1 activity 0.6305306863516831 1.0466073550326949 0.2952807082790052 1.0 0.7216843472567769 4 Q13309,P63208 2
Sumoylation of dna methylation proteins 0.6275280898876388 1.0338854757707887 0.301189705761955 1.0 0.7300495327268103 4 O00257,P26358,Q99496 3
Rap1 signalling 0.6269320557881974 1.0313617742429206 0.3023711995660851 1.0 0.7301906214303406 4 P17612 1
Phase ii conjugation of compounds 0.3340530923672025 1.0305645123555127 0.3027450849775062 1.0 0.7301906214303406 31 P28161,O75223,Q9NZL9,P78417,Q96IU4,Q8WUX2,Q9UI30,P21266,P14550,Q96KP4,P10768,O43708 12
Glutathione synthesis and recycling 0.5363821889201801 1.0278116725610729 0.3040384244770071 1.0 0.7301906214303406 6 O75223 1
Diseases of dna repair 0.3876505961309702 1.02584226667585 0.304965939543472 1.0 0.7301906214303406 17 P38398,Q96B01,P78549 3
Dna double strand break repair 0.2844296657597288 1.0204464480923698 0.3075167747393976 1.0 0.7301906214303406 67 Q9NXR7,Q8N2W9,P35244,O00213,Q04323,Q9NY27,O96017,P38398,Q9NR33,Q9UGN5,Q15054,Q9UQ84,Q96B01,P39748,P60510,P53041,P15927,P24941,Q92993 19
Transport of connexons to the plasma membrane 0.5761320092355076 1.0193917321043664 0.3080170297442071 1.0 0.7301906214303406 5 P04350 1
Gap junction assembly 0.5761320092355076 1.0193917321043664 0.3080170297442071 1.0 0.7301906214303406 5 P04350 1
Ras activation upon ca2 influx through nmda receptor 0.5338769148188958 1.0156671544238882 0.3097879140947372 1.0 0.7304488686835775 6 Q13555,Q92796,Q13557 3
Oncogene induced senescence 0.4521616692286515 1.0137585684437591 0.3106979694963949 1.0 0.7304488686835775 10 P42771 1
Rab regulation of trafficking 0.3149059199153092 1.0107361076196968 0.3121427503650098 1.0 0.7313184092160716 40 P60520,Q9Y2L5,Q15276,Q9Y296,P62330,Q15286,P61026,Q92930,P62258,P61006 10
Tp53 regulates transcription of cell cycle genes 0.3756361214623236 1.0053843863840346 0.3147117952026881 1.0 0.7350176795852256 18 O14965,O75175,Q9Y3B8,P12004,Q9UIV1,Q99873,P30307,P06493,Q86X55,P24941,P20248 11
Activation of bh3 only proteins 0.4375867866346742 0.9996855697505196 0.3174626976162387 1.0 0.7390115255984573 11 Q96FJ2,P31946,Q9Y3B8,P61981,P62258,P63167 6
Deubiquitination 0.2735689663678534 0.9842233749130718 0.3250056951350279 1.0 0.7479871751892054 113 Q9NXR7,Q9Y5K5,P49720,Q9NZL9,P25787,Q9UPT9,Q14318,Q9Y5T5,O00487,P48556,Q13200,O00233,Q9UNM6,P62191,Q9UL46,P20618,P38398,P25788,P61586,Q9Y277,Q96FW1,Q15750,Q70CQ2,P17980,O75832,P28072,P28074,O60493,P61289,Q13485,P28066,P62333,P85037,P25789,P06493,Q06323,P54578,Q13309 38
Defects in biotin btn metabolism 0.4845700146749607 0.9736811934914636 0.3302148579501933 1.0 0.7513531931943174 7 Q96RQ3,P50747 2
Mastl facilitates mitotic progression 0.6053324143664154 0.9403480731440192 0.3470390483464574 1.0 0.7667157812705119 4 P06493,P30153 2
Vitamin c ascorbate metabolism 0.7582818641212853 0.940307218131389 0.3470599981680142 1.0 0.7667157812705119 2 P78417 1
Defective intrinsic pathway for apoptosis 0.3912728115351609 0.9344654409125296 0.3500638547136701 1.0 0.7694902069557453 15 P04179,P42771,P30307 3
The phototransduction cascade 0.5143003815254157 0.9212549238352122 0.3569173490044766 1.0 0.7749581583889247 6 P50579,P49356 2
Complex i biogenesis 0.3325902970946851 0.9159828505629778 0.3596758897707639 1.0 0.7785667126135438 26 O75380,P51970,O96000,Q8IUX1,Q9P032,Q9Y6M9,P19404,O75489,P49821,P03915,Q9BU61 11
Trna processing in the mitochondrion 0.5987408006269215 0.9127774105798672 0.3613596212126084 1.0 0.7797264164666677 4 Q99714 1
Er to golgi anterograde transport 0.2666670038676251 0.9116701707256908 0.361942371106797 1.0 0.7797264164666677 78 P54920,P47755,P56962,Q9Y296,P83436,P04350,Q9BUF5,Q9UP83,P61923,O14579,Q9H0V9,P61163,O15027,P63167,P18085 15
Platelet sensitization by ldl 0.511254643917754 0.9066594866950688 0.3645868937183372 1.0 0.7799152922853778 6 Q13362,P30153,Q16539 3
Phase 0 rapid depolarisation 0.7492981471083716 0.9051728117143594 0.3653738431130824 1.0 0.7799152922853778 2 Q13557 1
Sema4d in semaphorin signaling 0.4329208348265151 0.902287810592138 0.3669039990275493 1.0 0.7799695244561092 10 P61586,P60660 2
Defects in vitamin and cofactor metabolism 0.4133436962380603 0.9022666422859382 0.3669152410821696 1.0 0.7799695244561092 12 Q96RQ3,Q9Y4U1,P50747 3
Biological oxidations 0.2808800592183498 0.8978174714521753 0.3692828685562679 1.0 0.7818905422353821 47 P28161,O75223,Q9NZL9,P78417,Q96IU4,O43488,Q8WUX2,P00387,Q9UI30,P21266,P14550,Q15185,Q96KP4,Q86WA6,P10768,O43708,P11766 17
Smooth muscle contraction 0.4200652759259972 0.8949939146238529 0.3707903410085484 1.0 0.7835153039168733 11 P60660,P04083 2
Creb1 phosphorylation through nmda receptor mediated activation of ras signaling 0.4307890839974216 0.8900318993929236 0.3734487577852272 1.0 0.7868012249209416 10 Q92796,Q15418,Q13555,Q13557 4
E3 ubiquitin ligases ubiquitinate target proteins 0.3686871125078149 0.8900229945760596 0.3734535391526159 1.0 0.7868012249209416 17 P50542,P12004,Q9GZS3,Q5VTR2,O95999 5
Condensation of prometaphase chromosomes 0.4304179138561818 0.8879002255759194 0.3745944233853 1.0 0.788035675862409 10 P67870,P06493 2
Ret signaling 0.4677599881729707 0.8856445577280051 0.3758090929262341 1.0 0.7894214673894266 7 P19174,Q06124,P17612 3
Maturation of sars cov 1 nucleoprotein 0.7461387250772298 0.8840914847208765 0.3766468295423335 1.0 0.7900125523635356 3 P49840,Q8IXQ6 2
Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways 0.3835316690028224 0.8825996359608234 0.3774526253305137 1.0 0.7905349970049108 15 Q13404,Q15750,P52564,Q16539,P42575,Q9Y2Z0 6
Transcription of the hiv genome 0.3171085615163114 0.8808732978128231 0.378386401523934 1.0 0.7913235495787722 32 O60942,Q9Y5B9,P62487,P32780,P19387,O15514,P52657,P18615,Q15370,Q00403,Q15369 11
Pentose phosphate pathway 0.4273792014953542 0.8704748629227372 0.3840409505168511 1.0 0.8019678672557775 10 P60891 1
Toll like receptor tlr1 tlr2 cascade 0.3302827357622498 0.8550387605098104 0.392529690092827 1.0 0.8093488872927167 24 Q15418,P09429,Q13404,Q15750,P52564,Q16539,P63208,P51617,P51452 9
Tak1 activates nfkb by phosphorylation and activation of ikks complex 0.4615611546531891 0.8534490612621851 0.3934103243671663 1.0 0.8093488872927167 7 Q13404,P09429,Q15750 3
Runx3 regulates p14 arf 0.7360292052794309 0.8473636147463324 0.3967924786013981 1.0 0.8098208834567121 3 P42771,Q13951 2
E2f enabled inhibition of pre replication complex formation 0.459780054857944 0.8442299382824544 0.3985409280078031 1.0 0.8098208834567121 7 O43929,P06493 2
Traf6 mediated irf7 activation in tlr7 8 or 9 signaling 0.7324536777091598 0.8399946513771808 0.4009113854342438 1.0 0.8112893908837538 2 Q13404 1
Nade modulates death signalling 0.730974445380528 0.8291123468549736 0.4070408378043901 1.0 0.8152298867168322 3 P42575,P62258 2
Dna damage bypass 0.3221383366974145 0.8264939757132308 0.4085239340248265 1.0 0.8170478680496531 26 Q15054,P35244,P15927,Q15004,P40937,Q9NR33 6
Aggrephagy 0.3672365564622193 0.8239760117772122 0.4099531882375808 1.0 0.8173549349548437 16 Q96FJ2,Q9BUF5,Q13404,P04350,Q99497,P63167 6
Assembly of collagen fibrils and other multimeric structures 0.7293273576582249 0.8231824038974067 0.4104042736780307 1.0 0.8173549349548437 3 P07858 1
Cyclin a b1 b2 associated events during g2 m transition 0.3920597058542971 0.8221364015128114 0.4109992700515135 1.0 0.8173935062649148 13 P30307,P06493,O95067,Q9Y570,P24941,P63151,P20248 7
Separation of sister chromatids 0.2673704690093831 0.7984470250918562 0.4246111233879017 1.0 0.8340666498234787 120 Q96FJ2,Q96BD8,P49720,P25787,P36873,Q14674,Q13042,O43684,O00487,P48556,Q13200,Q13362,O00233,P04350,Q9BUF5,Q6P1K2,Q9UNM6,Q9UL46,P20618,Q9Y266,Q9NSP4,P25788,Q96DE5,Q9H900,P17980,O75832,P28072,P28074,P61289,P28066,Q13257,P62333,P25789,P50748,Q8N0S6,Q8NBT2,Q06323,Q9HBM1,Q15691,P63167 40
Class i mhc mediated antigen processing presentation 0.2703094974376318 0.7825063151646269 0.4339170754507679 1.0 0.8475409176617477 125 Q9BSL1,Q5GLZ8,Q9Y508,P49720,P09429,P25787,O95352,Q13042,O00487,P48556,Q15369,Q13200,O00233,Q9UNE7,Q9UNM6,Q9UL46,P63208,P20618,Q15370,P25788,P60059,P61081,Q9H2C0,P17980,P04439,O75832,P28072,P28074,P61289,P28066,P62333,Q05086,Q13404,P25789,Q8TDB6,Q8TBC4,Q06323,Q13309,P49427,O94822,Q63HN8 41
Synthesis of udp n acetyl glucosamine 0.5203938201518472 0.7715333194771254 0.4403908807331049 1.0 0.8590041904409464 5 O95394,Q9UJ70 2
Perk regulates gene expression 0.3514015003624176 0.7687942119050313 0.4420154855082576 1.0 0.8606476719375152 17 Q96B26,Q9Y3B2,P20042,Q13868,Q9Y2L1,Q9NQT4,Q9NPD3,P08243,Q5RKV6,Q9NQT5 10
Synthesis of ip2 ip and ins in the cytosol 0.5612907637404254 0.7587023918523815 0.4480306057812488 1.0 0.8628463223521469 4 Q96PE3 1
Extension of telomeres 0.299992801703396 0.7555005705050193 0.4499486901389016 1.0 0.8628463223521469 35 Q15054,P12004,P35244,P24941,P39748,P35250,Q9NY12,P15927,Q9NX24,P49643,P40937,P18858,P20248 13
Dual incision in tc ner 0.2979128738178614 0.7505019712483947 0.4529524370031326 1.0 0.8628463223521469 36 Q15054,P12004,P35244,P40937,P15927,P62487,P32780,P19387,O15514,Q9NR33 10
Budding and maturation of hiv virion 0.3950645716946039 0.7486104681353069 0.4540920208278503 1.0 0.8628463223521469 11 Q9NP79,Q9H9H4 2
Rna polymerase ii transcribes snrna genes 0.3004759168518689 0.7473676907743566 0.4548416425798927 1.0 0.8628463223521469 34 P08047,Q96P16,O15514,P52657,Q00403,Q9NP77 6
Interleukin 17 signaling 0.3200533809495625 0.7438235405972944 0.4569832365780772 1.0 0.8640695019186015 22 Q15418,Q13404,Q15750,P52564,Q16539,P63208,P51617,P51452 8
Insulin processing 0.3940436285934846 0.7427327733489596 0.4576434836002465 1.0 0.864167216372806 11 Q9Y4I1,Q8IYI6,Q9NV70,Q96KP1,Q8TAG9 5
Runx1 regulates expression of components of tight junctions 0.7055156702871954 0.7385035448870523 0.460208513824226 1.0 0.864858164073861 3 Q16625 1
Programmed cell death 0.2533894371891321 0.7381132805796553 0.4604456141125626 1.0 0.864858164073861 108 Q96FJ2,P49720,P09429,P25787,O00487,P48556,P62258,Q13200,P31946,P26583,O00233,Q9UNE7,Q9UNM6,Q07021,P62191,Q9UL46,P20618,O00560,P25788,P42771,Q16625,Q96GX9,P17980,O75832,P28072,P28074,P30419,P61289,P28066,P62333,P55212,P61981,P25789,Q06323,P63167,Q16611,Q9UJU6 37
G2 phase 0.704379562043806 0.7338221838153389 0.4630571183736605 1.0 0.8668803661802634 2 P24941 1
Regulation of localization of foxo transcription factors 0.4744608525965014 0.7332420736624348 0.4634107981627691 1.0 0.8668803661802634 6 P31946,P61981,Q9Y3B8 3
Erythropoietin activates phospholipase c gamma plcg 0.7038180797304963 0.7317350886326583 0.4643302752339302 1.0 0.8668803661802634 2 P07948 1
Insertion of tail anchored proteins into the endoplasmic reticulum membrane 0.3917107376823378 0.7293369469641099 0.4657955770391133 1.0 0.8668803661802634 11 P60059,O43765,P46379,Q7L5D6,P51648 5
Gab1 signalosome 0.5516853932584322 0.7200820488472858 0.4714744793685859 1.0 0.8754171995499588 4 Q06124,P41240,P62993 3
Receptor type tyrosine protein phosphatases 0.6984839977540805 0.7119866180442374 0.476473062694672 1.0 0.8824983663942586 2 P10586 1
Mitochondrial iron sulfur cluster biogenesis 0.5065062847719571 0.711663115163101 0.4766734133974621 1.0 0.8824983663942586 5 Q86SX6,Q86U28 2
Sulfur amino acid metabolism 0.388127568219063 0.7088603011394193 0.4784111727571509 1.0 0.8845623246291073 11 Q96GX9,Q13126,Q9BV57,P25325 4
Intra golgi and retrograde golgi to er traffic 0.2399732352189425 0.699965159587284 0.4839490628232867 1.0 0.8890138023403197 88 P54920,P47755,Q16706,P83436,P33908,P04350,Q9UP83,O14579,P68402,P40616,P63167,P18085 12
Heme degradation 0.5428646080145079 0.6850200330637247 0.4933312796202322 1.0 0.8976631780899277 4 P30519,P30043 2
Hsf1 activation 0.3608209696707369 0.679835331320854 0.4966087326163371 1.0 0.8994698983612227 14 P35244,P62258,Q15185 3
Synthesis of gdp mannose 0.6843583263128403 0.6651784372155414 0.5059363704398319 1.0 0.906616248460192 3 Q9Y5P6,Q96IJ6 2
Ephb mediated forward signaling 0.3283486909086502 0.6636115788281971 0.506938944561544 1.0 0.906616248460192 18 P61586,O00401,P61160,O15144,P07948,O15145,P23528 7
Apex1 independent resolution of ap sites via the single nucleotide replacement pathway 0.6833672574833232 0.6617943037342477 0.5081030572476917 1.0 0.9075551462788958 3 Q96T60 1
Metalloprotease dubs 0.410493374058439 0.6540264800713635 0.5130947456506982 1.0 0.9141713159648576 8 P38398,Q9NXR7 2
Carboxyterminal post translational modifications of tubulin 0.4173924433670221 0.6304832878813088 0.5283784335687802 1.0 0.9274380416164004 7 P04350,Q9BUF5,Q9BVA1 3
Nostrin mediated enos trafficking 0.6754632229084874 0.6285426732688563 0.5296485009939049 1.0 0.9285195943349938 2 O00401 1
Transcriptional activation of mitochondrial biogenesis 0.3596101703826193 0.6261423330004223 0.5312215876298803 1.0 0.9301290436922688 13 Q06546,P04179,P48735 3
Tp53 regulates metabolic genes 0.2805236428268229 0.6197149804962714 0.5354454512144791 1.0 0.9310605351342854 38 Q16881,Q13131,P00403,Q9NQ88,P54619,P30044,P00390,P62258 8
Post chaperonin tubulin folding pathway 0.3822607894651994 0.6194565258983504 0.5356156531238907 1.0 0.9310605351342854 10 P04350,Q9BUF5,Q9BVA1,P36404 4
Response of eif2ak1 hri to heme deficiency 0.5257360942577665 0.6181974121655959 0.5364452157152735 1.0 0.9310605351342854 4 P08243,P20042 2
Myd88 independent tlr4 cascade 0.2912749489384657 0.6117662074945232 0.5406924505111481 1.0 0.9310605351342854 28 Q6SZW1,Q15418,P30153,P09429,Q13404,Q15750,P52564,Q16539,P63208,P51617,P51452 11
Irak1 recruits ikk complex 0.6680785063136743 0.6102266344897773 0.5417116886041828 1.0 0.9310605351342854 3 Q13404 1
Ksrp khsrp binds and destabilizes mrna 0.3409620589020215 0.6078014458852976 0.5433191702175275 1.0 0.9310605351342854 15 Q96B26,Q9Y3B2,Q13868,Q9Y2L1,Q16539,Q9NPD3,Q5RKV6,Q9NQT5 8
Pka activation in glucagon signalling 0.5226157821849959 0.6062230849325814 0.5443666253862269 1.0 0.9310605351342854 4 P17612 1
Creb1 phosphorylation through the activation of adenylate cyclase 0.5226157821849959 0.6062230849325814 0.5443666253862269 1.0 0.9310605351342854 4 P17612 1
Pka mediated phosphorylation of creb 0.5226157821849959 0.6062230849325814 0.5443666253862269 1.0 0.9310605351342854 4 P17612 1
Ctla4 inhibitory signaling 0.3890295358649932 0.6042708639260821 0.5456635740176017 1.0 0.9310605351342854 9 P07947,P30153,Q13362,Q14738,P07948,P30154,Q06124,P12931 8
2 ltr circle formation 0.4458589924974095 0.6037653167659284 0.545999681515172 1.0 0.9310605351342854 6 P12956,P17096,O75531 3
Smad2 smad3 smad4 heterotrimer regulates transcription 0.4456332018966789 0.6027679406934283 0.5466630769276173 1.0 0.9310605351342854 6 P08047 1
P75 ntr receptor mediated signalling 0.3024959209214723 0.6015258169698807 0.5474898217162876 1.0 0.9310605351342854 21 P61586,O15013,O75962,P42575,P51617,P62258 6
Toll like receptor 9 tlr9 cascade 0.293605625588311 0.5923962920949867 0.5535852486989152 1.0 0.9352946403884104 26 Q15418,P09429,Q13404,Q15750,P52564,Q16539,P63208,P51617,P51452 9
Atf4 activates genes in response to endoplasmic reticulum stress 0.3455935225729452 0.5878397483738281 0.5566398614479713 1.0 0.9352946403884104 14 Q96B26,Q9Y3B2,Q13868,Q9Y2L1,Q9NPD3,P08243,Q5RKV6,Q9NQT5 8
Synthesis of ketone bodies 0.5177683574227127 0.5877531049564823 0.5566980249108795 1.0 0.9352946403884104 4 Q9BUT1 1
Clathrin mediated endocytosis 0.2532263739053661 0.5861672639660177 0.5577631181135381 1.0 0.9352946403884104 59 O00401,Q9BT78,Q8N6T3,O15144,Q8NC96,P62330,O14657,Q9UBW8,Q9UNS2,Q92905,Q99961,O15145,P09497,Q7L5N1 14
Recruitment of mitotic centrosome proteins and complexes 0.2794914442173261 0.5808882657061305 0.5613157613909976 1.0 0.9387247573617994 36 P04350,P06493,P07437,P17612,Q9H6D7,P62258,P63167 7
Metabolism of porphyrins 0.3840032754700256 0.5784498047257545 0.5629604769917835 1.0 0.9387247573617994 9 P30043,P06132,P30519 3
Integration of provirus 0.4062891595009575 0.5768832118570861 0.5640183522209661 1.0 0.9387247573617994 7 P12956,P17096,O75531 3
Regulation of glycolysis by fructose 2 6 bisphosphate metabolism 0.4740433120572036 0.5763154357415718 0.5644019913821834 1.0 0.9387247573617994 5 P17612 1
Hdr through single strand annealing ssa 0.2989788529270743 0.5759047669439372 0.5646795533630395 1.0 0.9387247573617994 21 Q9UQ84,P35244,P15927,P38398,Q92993 5
G2 m dna damage checkpoint 0.2667361669967067 0.5715256149598813 0.567643402020372 1.0 0.9387247573617994 42 Q9NXR7,Q8N2W9,P35244,Q9UQ84,P30307,P15927,O96017,P06493,P40937,P38398,P62258,Q92993 12
Regulation of tp53 activity 0.2495692546675428 0.5713374845711181 0.5677708969910311 1.0 0.9387247573617994 66 P19784,Q96S44,Q13362,O14965,P42771,Q13131,P35244,Q9UQ84,P54619,Q16539,P15927,P67870,O96017,P06493,P40937,P38398,P24941,Q92993 18
Cargo recognition for clathrin mediated endocytosis 0.2781514466414193 0.5690285604230887 0.5693367579983533 1.0 0.9389758378137766 36 Q9BT78,Q8NC96,O14657,Q9UBW8,Q9UNS2,Q92905,Q99961,P09497,Q7L5N1 9
Striated muscle contraction 0.4376859020375914 0.5679488634168289 0.5700696912513343 1.0 0.9390939229430334 6 P67936 1
Tp53 regulates transcription of cell death genes 0.4028739722627145 0.5606536090452655 0.5750336980852173 1.0 0.9433612402544568 7 P42575,Q92597,P55212 3
Phosphorylation of emi1 0.6525868183982088 0.5593054855335756 0.5759532522617274 1.0 0.9433612402544568 3 P06493 1
G0 and early g1 0.3699662424189187 0.5545854402824716 0.5791782500657903 1.0 0.9442512369553852 10 P12004,P24941,P06493,Q5TKA1 4
Neurotransmitter receptors and postsynaptic signal transmission 0.2535840398427151 0.5545262389125187 0.5792187535192204 1.0 0.9442512369553852 46 Q92796,Q13131,P04350,Q9BUF5,P17612,Q9Y2X7 6
Creatine metabolism 0.6505127635167864 0.5525986402076871 0.5805382733245992 1.0 0.9442890585577672 3 Q14353 1
Rhobtb gtpase cycle 0.2799316783703702 0.5424347160445665 0.5875190695383676 1.0 0.9473121624255664 30 Q15208,Q8IYB3,Q96DH6 3
Biotin transport and metabolism 0.3765315935489831 0.5406391363605886 0.5887563370701621 1.0 0.9473121624255664 9 Q96RQ3,P50747 2
Aurka activation by tpx2 0.2761147462787471 0.5401870305697206 0.5890680559308274 1.0 0.9473121624255664 35 P04350,P61163,P06493,P07437,P17612,Q9H6D7,P62258,P63167 8
Activation of ppargc1a pgc 1alpha by phosphorylation 0.6433176737127173 0.5295469835000876 0.596426060884125 1.0 0.9526715483188496 3 P54619 1
Base excision repair ap site formation 0.459037681257997 0.5165054567419575 0.6055014287735938 1.0 0.9606838311268192 5 P78549 1
Meiotic recombination 0.3313402636861356 0.5051986927461043 0.6134192883984104 1.0 0.9666666553842984 14 P35244,P24941,P11802,P38398 4
Sirt1 negatively regulates rrna expression 0.4944561426447927 0.5014139771180373 0.6160798050160494 1.0 0.9666666553842984 4 Q96EB6 1
Erk mapk targets 0.3581879764366898 0.4944026623601538 0.6210218341243041 1.0 0.9687795917650064 10 P51452,Q15418,Q16539 3
Mapk targets nuclear events mediated by map kinases 0.3581879764366898 0.4944026623601538 0.6210218341243041 1.0 0.9687795917650064 10 P51452,Q15418,Q16539 3
E2f mediated regulation of dna replication 0.3293676716133397 0.494068858137328 0.6212575503887461 1.0 0.9687795917650064 14 O43929,P30153,O43913,Q9UBD5,P06400,P06493,P49643 7
Hiv transcription initiation 0.309062523650044 0.4903287658158919 0.6239012747514736 1.0 0.9687795917650064 17 P32780,P62487,O15514,P52657,Q00403 5
Cell death signalling via nrage nrif and nade 0.3286437504203769 0.490004552372092 0.6241306774672515 1.0 0.9687795917650064 14 P42575,O75962,P62258,O15013 4
Degradation of the extracellular matrix 0.3657323008705222 0.487329307690911 0.6260249816436567 1.0 0.9687795917650064 9 P07858 1
Synthesis of diphthamide eef2 0.4901851167251835 0.4860881519840204 0.6269046668740468 1.0 0.9687795917650064 4 Q9H2P9,Q9BQC3 2
Nuclear events kinase and transcription factor activation 0.3346695479941854 0.4852360748817982 0.6275088949877494 1.0 0.9687795917650064 13 P30153,P50570,Q15418,Q16539,P27361,P51452 6
Host interactions of hiv factors 0.2252043479858607 0.4847855155178701 0.627828498354132 1.0 0.9687795917650064 96 P49720,P25787,P17096,O00487,P48556,Q13200,Q15369,O00233,Q9UNM6,Q9UL46,P63208,P20618,O15504,Q15370,P25788,P17980,P04439,O75832,P28072,P28074,P61289,P28066,P62333,Q9BXS5,P25789,P62826,Q06323 27
Class a 1 rhodopsin like receptors 0.4130713962789309 0.4641091101992316 0.6425695750245246 1.0 0.9726605179166296 6 P04083 1
Peptide ligand binding receptors 0.4130713962789309 0.4641091101992316 0.6425695750245246 1.0 0.9726605179166296 6 P04083 1
Fgfr2 alternative splicing 0.3044524127191642 0.4622893108623665 0.6438738639729802 1.0 0.9726605179166296 17 P52597,P31483,P62487,P19387,O15514 5
Ticam1 rip1 mediated ikk complex recruitment 0.6212093166139981 0.4609640957067662 0.6448243648551166 1.0 0.973004567633726 3 Q13404 1
Recruitment of numa to mitotic centrosomes 0.2608764538694658 0.4600615466126041 0.6454720441626549 1.0 0.973004567633726 39 Q9BUF5,P04350,P06493,P07437,P17612,Q9H6D7,P62258,P63167 8
Protein folding 0.2565398922756288 0.4562606355180915 0.6482025671977205 1.0 0.9746097050664576 41 P04350,Q9BUF5,Q9UHV9,P61962,P67870,P19784,Q9NQP4 7
Rhobtb1 gtpase cycle 0.2800101213966183 0.4437863859122011 0.6571970321668337 1.0 0.9816790159097212 21 Q13098,Q9BT78,Q5VTR2,Q8N684,Q15208,Q8IYB3 6
Golgi cisternae pericentriolar stack reorganization 0.3479190001008826 0.4437462594854671 0.6572260461969692 1.0 0.9816790159097212 10 P62820,P06493,O95067,P61019 4
Ras processing 0.4388246770684451 0.4393925146773341 0.6603771493534831 1.0 0.9816790159097212 5 P49356 1
Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein 0.2722173380044013 0.4319372679773711 0.6657870074455072 1.0 0.9816790159097212 26 O95394,Q9Y5P6,Q9H553,Q86YN1,Q13630,P53602,P10619,Q9UJ70,Q8NFW8,Q96IJ6 10
Ovarian tumor domain proteases 0.336349252602722 0.4312282715180223 0.6663023992100867 1.0 0.9816790159097212 11 Q96FW1,P06493 2
Tp53 regulates transcription of caspase activators and caspases 0.4744165960287163 0.4309976660668971 0.6664700675223465 1.0 0.9816790159097212 4 P42575 1
Pd 1 signaling 0.6151038742279735 0.4273203607062479 0.6691460048004387 1.0 0.9816790159097212 2 P41240 1
Cobalamin cbl vitamin b12 transport and metabolism 0.4355401424280825 0.4272824993066562 0.6691735780891537 1.0 0.9816790159097212 5 Q9Y4U1 1
Defects in cobalamin b12 metabolism 0.4355401424280825 0.4272824993066562 0.6691735780891537 1.0 0.9816790159097212 5 Q9Y4U1 1
Cytochrome c mediated apoptotic response 0.403748851135706 0.4266090561080539 0.6696641004854067 1.0 0.9816790159097212 6 Q96GX9 1
Activation of gene expression by srebf srebp 0.2917183606810231 0.4248051880370539 0.6709786953718826 1.0 0.9816790159097212 18 P08047,P53602,Q03426 3
Role of lat2 ntal lab on calcium mobilization 0.6122964626614382 0.4187172109041014 0.6754228158759135 1.0 0.9816790159097212 2 P07948 1
Pi 3k cascade fgfr3 0.612296462661438 0.4187172109041011 0.6754228158759137 1.0 0.9816790159097212 2 Q06124 1
Pi 3k cascade fgfr2 0.612296462661438 0.4187172109041011 0.6754228158759137 1.0 0.9816790159097212 2 Q06124 1
Pi 3k cascade fgfr4 0.612296462661438 0.4187172109041011 0.6754228158759137 1.0 0.9816790159097212 2 Q06124 1
Stat5 activation 0.612296462661438 0.4187172109041011 0.6754228158759137 1.0 0.9816790159097212 2 Q06124 1
Stat5 activation downstream of flt3 itd mutants 0.612296462661438 0.4187172109041011 0.6754228158759137 1.0 0.9816790159097212 2 Q06124 1
Pi 3k cascade fgfr1 0.612296462661438 0.4187172109041011 0.6754228158759137 1.0 0.9816790159097212 2 Q06124 1
Nef mediated downregulation of mhc class i complex cell surface expression 0.4321418348250921 0.4148864813851218 0.6782250065997883 1.0 0.9818829078262672 5 P04439,Q9BXS5 2
Cdc6 association with the orc origin complex 0.3995523720426304 0.4100986967646517 0.6817335486827747 1.0 0.9818829078262672 6 O43929,Q9UBD5,Q99741 3
Cargo trafficking to the periciliary membrane 0.274691125160944 0.4057859646233227 0.6848998721950963 1.0 0.9839314487494258 20 Q8IYI6,P36405,P18085,P61006 4
Synthesis of pc 0.4294756678899576 0.4052585561199184 0.6852874667698465 1.0 0.9839314487494258 5 P67870,P19784 2
Synthesis of pe 0.6027512633352173 0.3900477582759012 0.6965012321434392 1.0 0.9960037760762172 2 P35790 1
Deadenylation of mrna 0.2882158406676527 0.3683383920670164 0.7126209289686867 1.0 1.0 17 Q9UIV1 1
Inactivation of csf3 g csf signaling 0.3867269542757104 0.3611779216029736 0.7179664457502115 1.0 1.0 6 Q15369 1
Processing of dna double strand break ends 0.2521949969459753 0.3564458030502909 0.7215067329628528 1.0 1.0 36 Q9NXR7,Q9NY27,Q8N2W9,P35244,Q9UQ84,P24941,P15927,P38398,P60510,Q92993 10
Signaling by csf3 g csf 0.3468446279358743 0.3551491502906463 0.7224778568881802 1.0 1.0 8 Q15369 1
Netrin 1 signaling 0.3092547616529708 0.3544800546128492 0.7229791490036783 1.0 1.0 13 O00401,Q00169,Q16539 3
Mtorc1 mediated signalling 0.3283535681416406 0.3527196582101258 0.7242986202925903 1.0 1.0 10 P06730,P31946,P62753 3
Disorders of transmembrane transporters 0.2252728644769184 0.3500983744782094 0.7262648707731951 1.0 1.0 74 O75477,O00233,P49720,P25787,Q9UNM6,O75832,Q9UL46,P20618,P61289,O15504,P28066 11
Diseases of mitotic cell cycle 0.2844687731526818 0.3478314324271984 0.7279667822484523 1.0 1.0 17 P11802,Q9UJX4,Q96DE5,P06400,Q9UJX6,Q13042,Q13309,P24941,P46100 9
Beta oxidation of pristanoyl coa 0.411778408229267 0.3436610369873761 0.731101216328033 1.0 1.0 5 O15254 1
Advanced glycosylation endproduct receptor signaling 0.3426825651972125 0.3378629871678676 0.7354664409940299 1.0 1.0 8 P47755 1
Toll like receptor cascades 0.2503702124115965 0.3359408277782553 0.7369154882844571 1.0 1.0 35 Q6SZW1,Q15418,P30153,Q99538,P07858,P09429,Q13404,Q15750,Q13546,P52564,Q16539,P63208,P51617,P51452 14
Hiv infection 0.2500502871225444 0.3335052388992663 0.7387529355268514 1.0 1.0 143 P49720,Q9NZZ3,P25787,P17096,Q9H9H4,P62487,P19387,P18074,O15514,O00487,P52657,P48556,Q15369,Q13200,O00233,Q9UNM6,Q9UL46,P63208,P20618,O15504,Q9NP79,Q00403,Q15370,P18615,P25788,P39748,P17980,P04439,O75832,P32780,P28072,P28074,P30419,P61289,P28066,O60942,P62333,Q9BXS5,P25789,P62826,Q06323,Q9Y5B9,P18858 43
Ngf stimulated transcription 0.5753560383216675 0.331399641429987 0.7403426357042928 1.0 1.0 3 P50570 1
Cell cycle checkpoints 0.2660981605660898 0.3274526456385762 0.7433255536774934 1.0 1.0 168 Q96FJ2,Q96BD8,Q9NXR7,Q8N2W9,P49720,P35244,P25787,P36873,Q9UBD5,P30307,Q13042,O43684,P40937,O00487,P48556,P62258,Q13200,P31946,Q13362,O00233,Q6P1K2,Q9UNM6,O96017,Q9UL46,P20618,Q99741,P38398,Q9Y266,Q9NSP4,P25788,P42771,Q9UQ84,Q96DE5,Q9H900,P17980,P16104,O75832,P28072,P28074,O95067,P61289,P28066,O43929,Q13257,P62333,P61981,P25789,P50748,P15927,Q8N0S6,Q8NBT2,P06493,Q06323,Q9HBM1,P24941,Q15691,P63167,Q92993 58
Asparagine n linked glycosylation 0.2368466838155374 0.3255717211340838 0.7447484106835367 1.0 1.0 126 Q9Y296,P33908,Q9UP83,Q04323,P54920,Q16706,Q9H553,P04350,Q9BUF5,P61923,Q9H0V9,P61163,P53602,O15027,Q9UJ70,P47755,Q86YN1,P83436,Q8NFW8,P18085,P56962,P04844,O14579,P63167 24
Polymerase switching on the c strand of the telomere 0.2797906981743213 0.3229067297426311 0.746765879515646 1.0 1.0 17 P35251,Q15054,P12004,Q8WVB6,P35250,P49643,P40937 7
Formation of tubulin folding intermediates by cct tric 0.2976626302450094 0.3002798425887344 0.7639637074776078 1.0 1.0 13 P49368,Q9BVA1,P78371,P50991,P40227,P50990,P04350,Q13509,Q9BUF5,P68371,P17987,Q99832 12
Gdp fucose biosynthesis 0.5701852891634054 0.2995342228320082 0.7645324639060262 1.0 1.0 2 Q13630 1
Tp53 regulates transcription of dna repair genes 0.2459871554496915 0.2962405854122989 0.7670463563726706 1.0 1.0 33 Q9Y5B9,Q14241,Q9NYV4,P62487,P32780,P19387,P18074,O15514,Q9BXW9,P38398,Q15370,P18615,Q15369 13
Telomere maintenance 0.2222906197841888 0.2927173551132927 0.7697382031984863 1.0 1.0 47 Q15054,P35244,P24941,P39748,Q9NY12,P15927,P62487,P19387,O15514,P18858 10
Tp53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain 0.3208532784896218 0.2875245400299975 0.7737107146083964 1.0 1.0 9 Q9UIV1 1
Galactose catabolism 0.5648512071869878 0.2858637398402451 0.7749824867376238 1.0 1.0 2 Q96G03 1
Gpvi mediated activation cascade 0.3653680272483159 0.285410186100298 0.7753299045636399 1.0 1.0 6 P61586 1
Resolution of d loop structures 0.2929279497797865 0.2792601512067078 0.7800451849389232 1.0 1.0 13 P38398,Q96B01 2
Resolution of d loop structures through synthesis dependent strand annealing sdsa 0.2929279497797865 0.2792601512067078 0.7800451849389232 1.0 1.0 13 P38398,Q96B01 2
Formation of incision complex in gg ner 0.2808402742132638 0.2778546797346173 0.781123914771862 1.0 1.0 15 Q9UGN5,P35244,P15927,P32780,Q92889,P18074,P19447 7
Cell extracellular matrix interactions 0.3264639471639238 0.2739219106326006 0.7841446331000721 1.0 1.0 8 Q15404 1
Signaling by hippo 0.3619041079444504 0.273856696267662 0.784194751125769 1.0 1.0 6 P31946,P62258 2
Pyroptosis 0.3352567191121893 0.2737178902541854 0.7843014282004532 1.0 1.0 7 Q16611 1
Signal regulatory protein family interactions 0.551530468969381 0.2720123552241084 0.7856125193245886 1.0 1.0 3 Q06124,P62993 2
Pi5p regulates tp53 acetylation 0.3851275697888378 0.2593480685310741 0.7953666944335762 1.0 1.0 5 Q8TBX8,Q13526,P52564 3
Erks are inactivated 0.330334551588425 0.2560714210802106 0.7978956890892503 1.0 1.0 7 P30153,Q14738,P27361,P51452,P28482,P30154 6
Downregulation of erbb4 signaling 0.5513756316676175 0.2528711996678744 0.8003677456579898 1.0 1.0 2 Q96J02 1
Netrin mediated repulsion signals 0.5513756316676175 0.2528711996678744 0.8003677456579898 1.0 1.0 2 Q06124 1
Vitamin d calciferol metabolism 0.3796522558036652 0.2434139619809564 0.8076847289257247 1.0 1.0 5 Q8N2W9 1
Formation of xylulose 5 phosphate 0.5372086492558177 0.2392447515280178 0.81091580332771 1.0 1.0 3 P14550,Q00796 2
Selective autophagy 0.234981208586841 0.2294160914995695 0.8185455304465705 1.0 1.0 34 Q96FJ2,P50542,P04350,Q9BUF5,Q13404,P54619,P67870,P19784,Q99497,O96008,P63167 11
Runx2 regulates osteoblast differentiation 0.3454187745924774 0.2219244280589115 0.8243727138120405 1.0 1.0 6 P07947,P06400,Q13951,P27361,P12931 5
Signaling by erythropoietin 0.3714362494389058 0.220451852909139 0.8255192657635422 1.0 1.0 5 P19174,P46109,P07948 3
L1cam interactions 0.2196783246214044 0.2045258511563522 0.8379425926279016 1.0 1.0 43 Q92796,P04350,P67870,P19784,O00560 5
Apc cdc20 mediated degradation of nek2a 0.273826988297017 0.2016661442209444 0.8401777317607668 1.0 1.0 13 Q13042,O43684,Q96DE5 3
Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components 0.273826988297017 0.2016661442209444 0.8401777317607668 1.0 1.0 13 Q13042,O43684,Q96DE5 3
Prolonged erk activation events 0.3372681281618959 0.1982018003596078 0.8428871789463965 1.0 1.0 6 P31946,Q9ULH0,P27361,P46109,P28482 5
Phosphorylation of the apc c 0.2716333552611494 0.1935352780080483 0.8465397804276018 1.0 1.0 13 Q13042,P06493 2
Rho gtpases activate formins 0.208119517803466 0.1932756392120393 0.84674310370827 1.0 1.0 74 P61586,Q96BD8,Q9BUF5,P04350,P36873,Q6P1K2,P50748,P35080,Q8N0S6,P07737,Q9H900,O43684,P63167 13
Activation of nima kinases nek9 nek6 nek7 0.3607030453569145 0.1922246790149618 0.8475662153056895 1.0 1.0 5 P06493,O95067 2
Transcriptional regulation by tp53 0.2347628496388109 0.1872997156969151 0.851425645883233 1.0 1.0 142 Q13131,P12004,P35244,Q9NQ88,P54619,P30307,Q9NYV4,P62487,P19387,P18074,P40937,O15514,P19784,Q99873,P62258,Q15369,Q16881,P31946,Q13362,O75175,P52564,P30044,O96017,Q86X55,P00390,P38398,Q15370,P18615,O14965,P42771,Q9H3P2,Q9UQ84,Q9UIV1,Q16539,P67870,P32780,Q9BXW9,P42575,Q96S44,P55212,P00403,P61981,P15927,Q92597,P06493,Q9Y5B9,P24941,Q14241,Q92993,Q13526 50
Apobec3g mediated resistance to hiv 1 infection 0.510187214264699 0.1838014724013102 0.8541692010088382 1.0 1.0 3 P17096 1
Apc c cdc20 mediated degradation of cyclin b 0.2722717930989107 0.1793523063434741 0.8576610781075551 1.0 1.0 12 Q13042,P06493 2
Gap junction trafficking and regulation 0.2662762643358011 0.1743852657885547 0.8615626931027696 1.0 1.0 13 P04350,Q9BUF5 2
Golgi to er retrograde transport 0.2067482198346854 0.1735192749983241 0.862243278424065 1.0 1.0 71 Q96FJ2,Q9Y3B3,P54920,P62820,P04350,Q9BUF5,P61923,Q14807,P61163,P84085,P52907,P48444,P47755,Q9BVA1,Q8N6T3,Q15042,Q9NZ32,P18085,Q13561,O14579,P68402,P63167 22
Camk iv mediated phosphorylation of creb 0.5027451660569197 0.1700434937806056 0.8649759316132846 1.0 1.0 3 Q13557 1
Inhibition of replication initiation of damaged dna by rb1 e2f1 0.3010964295754865 0.1626935057402579 0.8707597605313209 1.0 1.0 7 P49642,P30153,Q14181,P06400,P49643,P30154 6
Glycerophospholipid biosynthesis 0.223143052391836 0.1613592960260568 0.87181042358023 1.0 1.0 30 Q9NPH0,Q8NAN2,O94830,P67870,O96017,P48651,P19784,P48739 8
Signaling by wnt in cancer 0.2918238742834068 0.1580203404948603 0.8744407706903614 1.0 1.0 8 Q13362,Q13363,P30153 3
Transmission across chemical synapses 0.2049667793438903 0.1513951712199211 0.8796639983681125 1.0 1.0 57 Q92796,Q13131,P04350,P17612,Q9Y2X7,Q96QD8 6
Hdr through mmej alt nhej 0.2882522319278721 0.1478255122053667 0.8824804747064474 1.0 1.0 8 Q9UGN5,P39748 2
Suppression of apoptosis 0.317882898902647 0.147280055733837 0.8829109740201773 1.0 1.0 6 Q63HN8 1
Signalling to erks 0.264002251618354 0.1400803630840052 0.8885964955929706 1.0 1.0 11 P31946,P62993,Q16539,P28482,Q9ULH0,P27361,P46109,Q02750,P11233,P12931 10
Lipophagy 0.3674157303370791 0.1395955394802998 0.8889795650920762 1.0 1.0 4 O60664,P54646,P54619 3
Death receptor signalling 0.2180056201980911 0.1360949768821807 0.8917461984500412 1.0 1.0 32 P61586,O15013,O95429,Q15750,O75962,P42575,P51617,P62258 8
Trafficking and processing of endosomal tlr 0.4825233145446976 0.1360160254760626 0.8918086122028195 1.0 1.0 3 P07858 1
Translation 0.2749587899441476 0.1342993894005763 0.8931658360567543 1.0 1.0 224 Q7Z2W9,P49458,P62841,P09132,Q9Y285,Q9Y3U8,P63220,P61513,P60842,P39019,P60059,P49770,Q9BYD3,P82933,Q9H2U2,Q9UGM6,O43324,P20042,O75821,P06730,P61927,P62888,O15372,P62854,P62701,P37108,P26373,P62277,P62263,P61247,Q9BYC9,P56537,P62847,Q14232,Q07020,P61313,Q9UBQ5,P08708,P32969,P62899,P51571,P61254,O00303,Q7L3T8,P62913,Q12904,P82663,P62081,P42766,Q9Y2Q9,P46778,P46776,P62495,P62857,Q15056,P63173,Q15181,P62906,Q05639,P62273,P62249,P61009,P62753,P54577,P05386,Q13144,P08865,P18621,O60841,Q9NR50,Q9UI30,P05388,P62244,P50914,P46777,P24534,P62910,P84098,Q96I59,Q9NP92,Q14240,P04844,P30050,P60866,P62829,P62280 86
Heme biosynthesis 0.3352065186850268 0.1335631842685855 0.8937479979768268 1.0 1.0 5 P22830,P36551,P06132,P08397 4
Interleukin 3 interleukin 5 and gm csf signaling 0.2682754050433528 0.1321115088015823 0.894896092996966 1.0 1.0 10 P62993,P07948,P17612,P46109,Q06124 5
Signal transduction by l1 0.2664449802540432 0.1270281500332783 0.8989181185167094 1.0 1.0 10 P67870 1
Translocation of slc2a4 glut4 to the plasma membrane 0.2084240764657172 0.1227949796671586 0.9022694498194516 1.0 1.0 41 Q9Y4I1,P04350,Q8IYI6,Q9BUF5,P54619,Q8TAG9,P61026,P62258,P61006 9
Protein protein interactions at synapses 0.2369375858434276 0.122026540861763 0.9028779987720528 1.0 1.0 16 Q92796,O95197,Q9HCM4,Q13136,P10586,Q9UJU6 6
Signaling by alk in cancer 0.2132619334018721 0.1166194449630033 0.9071616280159592 1.0 1.0 34 Q9H6R7,P62753,P67936,P63208 4
Signaling by egfr 0.2514076576576584 0.1150273764059657 0.9084234228286284 1.0 1.0 12 P19174,P01111,P41240,P62993,Q13685,P42566,P22681,Q99961,P60953,Q06124,P12931 11
Protein ubiquitination 0.2156465223872018 0.1112783146179139 0.9113956510214763 1.0 1.0 25 P50542,P12004,Q9GZS3,Q5VTR2,O95999,P49427 6
Regulated necrosis 0.2151201256874391 0.1079727924503023 0.9140172744906964 1.0 1.0 20 O00560,P09429,Q16611 3
Diseases of programmed cell death 0.2094111059781508 0.101997101068475 0.9187589760968452 1.0 1.0 29 P04179,P42771,P30307 3
Rsk activation 0.3452247191011157 0.1009781912966502 0.9195677724970226 1.0 1.0 4 P27361,Q15418,P51812 3
Rhov gtpase cycle 0.2123652522105156 0.0975173598437743 0.9223155487718772 1.0 1.0 21 O43639,Q9Y2X7 2
Purine ribonucleoside monophosphate biosynthesis 0.2538923124899205 0.0949653195064997 0.9243423734131448 1.0 1.0 10 P20839 1
Pp2a mediated dephosphorylation of key metabolic factors 0.4507160909856676 0.0923524742988747 0.9264179980046868 1.0 1.0 3 P30153,P30154 2
Nrage signals death through jnk 0.2512661789533033 0.0888747150856743 0.9291814784547026 1.0 1.0 10 Q92888,O15013,Q9NY61,P63000,Q92974,O75962,Q9H8V3,Q12802,Q14344 9
Regulation of pyruvate dehydrogenase pdh complex 0.2576645309238029 0.0887290660001528 0.9292972323058168 1.0 1.0 9 Q15118,Q15120 2
Oncogenic mapk signaling 0.2062816447509277 0.0882312606359502 0.9296928718018838 1.0 1.0 34 P62140,P31946,P51114,P36873,Q99956,O95352,Q13555,Q9NRY5,Q13557 9
Calcineurin activates nfat 0.4567658618753701 0.0876230536660752 0.9301762784759088 1.0 1.0 2 Q12968 1
Rhobtb3 atpase cycle 0.4434147711317012 0.0839818917981105 0.933070829151856 1.0 1.0 3 Q15345,O60664 2
Gastrin creb signalling pathway via pkc and mapk 0.2637053696935598 0.0742644388228109 0.940799972574388 1.0 1.0 7 P17252,P62993,P27361,Q15418,P51812,P28482 6
Ca dependent events 0.2484089493423271 0.0691726906146627 0.9448521607575764 1.0 1.0 9 P17612,Q13555,Q13557 3
Sealing of the nuclear envelope ne by escrt iii 0.2334396376623737 0.0651982193674384 0.948016178853328 1.0 1.0 11 P04350 1
Pyruvate metabolism 0.2103347791474364 0.0597074204210322 0.9523886616401298 1.0 1.0 17 Q15118,Q04760,Q15120 3
Erythropoietin activates ras 0.3107705977448149 0.0564176596324737 0.9550090890084464 1.0 1.0 4 P46109,P07948 2
Aberrant regulation of mitotic exit in cancer due to rb1 defects 0.2249986032752902 0.0550757365194073 0.9560781262503312 1.0 1.0 12 Q9UJX4,Q96DE5,Q13042,Q9UJX6,Q13309 5
Senescence associated secretory phenotype sasp 0.1981873772230025 0.0547032579711408 0.956374873765732 1.0 1.0 25 P24941,Q13042,P42771,Q96DE5 4
Regulation of cholesterol biosynthesis by srebp srebf 0.1954103540312669 0.0481247956012651 0.9616167850645696 1.0 1.0 26 P53602 1
Potential therapeutics for sars 0.1896729211533499 0.0458069799621454 0.9634640954471788 1.0 1.0 40 Q99720,P07437,P20839,P49356 4
Neuronal system 0.1847290155651983 0.045647571748725 0.963591151893451 1.0 1.0 68 Q92796,Q13131,P04350,P10586,P17612,Q9Y2X7,Q96QD8 7
Sulfide oxidation to sulfate 0.3983717012914233 0.0400462803695893 0.9680562294654408 1.0 1.0 2 Q16762 1
Fcgr activation 0.3886548722269028 0.0388260298195566 0.9690290916824208 1.0 1.0 3 P07948,P12931 2
Alpha oxidation of phytanate 0.3863669561503511 0.03754135478035 0.970053367025398 1.0 1.0 3 P51648 1
Hsf1 dependent transactivation 0.2015219842164636 0.037004641763174 0.9704813046851376 1.0 1.0 16 P54652,P50454,P25685,Q92598,P08238,P11142,P42345,Q13557,Q96B36,Q15185,P04792,Q8N122,P0DMV9,Q02790,Q13555 15
The activation of arylsulfatases 0.3899494665918163 0.0358542120202274 0.9713986058861293 1.0 1.0 2 P15289 1
Runx1 regulates genes involved in megakaryocyte differentiation and platelet function 0.2098000563221694 0.0352390502879146 0.9718891239288724 1.0 1.0 13 Q03164,Q15291,P62805,Q9UBL3,P61964,Q9HCE1,P16104,Q96ST3,Q13547,Q13951,Q99873,O15047 12
Costimulation by the cd28 family 0.1979137299125954 0.0351796644790812 0.9719364775876274 1.0 1.0 17 Q13177,P07947,P31751,P41240,Q14738,Q13362,P62993,P30153,Q6R327,P07948,P30154,P42345,P60953,Q06124,P63000,P12931 16
Peroxisomal lipid metabolism 0.2118833557984878 0.0337979294220631 0.9730382870856528 1.0 1.0 12 P51648,Q9UKG9,O15254 3
Egfr downregulation 0.2509836987071448 0.0327335821186937 0.9738870435749328 1.0 1.0 6 P62993,P42566,P22681,Q99961,P60953 5
Caspase mediated cleavage of cytoskeletal proteins 0.2264230104126574 0.0323320435294404 0.974207255515287 1.0 1.0 9 P55212,Q9UJU6 2
Signalling to ras 0.2635571789828636 0.0320729288332233 0.9744138919615076 1.0 1.0 5 P11233,P12931,P62993,Q16539 4
Constitutive signaling by akt1 e17k in cancer 0.2344672476806313 0.0294187834341532 0.976530592273557 1.0 1.0 7 P31751,O15111,Q6R327,P42345,Q96B36,P49840 6
Lysosome vesicle biogenesis 0.1939465873215713 0.0252985770320936 0.9798168089330348 1.0 1.0 16 P09497,Q9BXS5,Q9Y6B7,P49407,Q10567 5
Jnk c jun kinases phosphorylation and activation mediated by activated human tak1 0.2426748491903939 0.0246699273151676 0.9803182423030656 1.0 1.0 6 Q13404,Q15750 2
Mhc class ii antigen presentation 0.1763852081247729 0.0228160930110811 0.981796970999891 1.0 1.0 58 Q96FJ2,P50570,P68371,P10619,P53634,Q99538,P04350,Q9BUF5,Q14807,P61163,P52907,Q9UJW0,O94979,O75935,P47755,Q9BVA1,P07858,Q9NZ32,Q15436,O43237,Q10567,Q13561,Q9BXS5,Q9Y6G9,P53680,P63167 26
Golgi associated vesicle biogenesis 0.1838281615050268 0.0223900038870162 0.9821368540970844 1.0 1.0 31 P54920,Q8NC96,Q9Y6B7,Q9BXS5 4
Neurotransmitter clearance 0.3192026951151173 0.0176250991527783 0.9859379335568572 1.0 1.0 2 P21964 1
Influenza infection 0.199500637407208 0.0127490208819264 0.9898280286282268 1.0 1.0 131 P62847,P62487,P62841,P19387,O15514,P08865,P62913,P18621,P62081,Q07020,Q9Y3U8,P63220,P61313,P61513,P05388,P08708,P42766,P62244,P50914,O15504,P46777,P62910,P84098,P32969,P46778,P62899,P46776,P62857,P63173,P61254,O00505,O00629,P62906,P62273,P62249,P62753,P19525,P30050,P61927,P60866,P62888,P62854,P62826,P05386,P62829,P26373 46
Traf6 mediated induction of tak1 complex within tlr4 complex 0.294398643112264 0.0119895472829802 0.9904339545177444 1.0 1.0 3 Q15750 1
Copii mediated vesicle transport 0.1785472422403838 0.0114679873367412 0.990850070519394 1.0 1.0 32 P54920,P56962,Q9Y296,Q9H0V9 4
Bmal1 clock npas2 activates circadian gene expression 0.2687578479802714 0.0102843354591311 0.9917944321664393 1.0 1.0 3 Q86X55 1
Serine biosynthesis 0.2604331100901669 0.0099512698495976 0.9920601664708428 1.0 1.0 3 P78330 1
Signaling by ntrks 0.1759206798866883 0.0068291700105935 0.994551153038973 1.0 1.0 34 P50570,P63010,Q8WX92,P27361,Q15418,P51452,P28482,P19174,P31946,P30153,P09496,Q14738,Q14839,O94973,Q9ULH0,P46109,Q02750,P63000,P11233,P12931,P01111,O95782,P61586,Q16539,Q00610,Q8IV63,Q06124,P51812,P30154,P62993,P40763,Q00535,P53680 33
Peptide hormone metabolism 0.1748713652178067 0.0041615481642855 0.9966795745548038 1.0 1.0 16 Q9Y4I1,Q8IYI6,P61009,Q9NV70,Q96KP1,Q8TAG9 6