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Transport of small molecules 0.522559007031437 4.7753546946500345 1.793907831171282e-06 0.0025011644413574 0.0025042953323165 163 Q9UNS2,Q9Y487,P12236,Q15904,Q9UHQ9,P49721,Q9BPX6,P45880,O95202,Q4KMQ2,Q6PIU2,P40855,Q8WWI5,P08183,Q8N4V1,P09601,P51790,P35610,P30519,Q9HD20,P12235,O15118,Q9Y277,P56589,P28074,P21796,Q70HW3,P20020,Q9H300,P98194,Q9Y4W6,P30825,Q9H936,Q9UBX3,P23634,Q9H2J7,P51798,Q658P3,Q99623,Q9GZP9,P35613,Q9BU23,Q96PU5,Q15043,P63218,O00487,Q8TAD4,Q9C0H2,P16615,Q96QD8,Q93050,Q9H0U3,Q10713,Q8TB61,Q9UBV2,Q9Y6M7,P05141,P05023,Q8WWC4,P43686,Q8WTV0 61
Metabolism of lipids 0.4566706882805057 4.059344146589323 4.921074065800113e-05 0.0663931719502155 0.0228993979861903 188 P14324,O00767,Q9NTJ5,Q9HCL2,Q15392,Q8WUK0,Q15067,Q8NF37,Q9H7Z7,Q9Y6K0,O15228,Q96N66,P40939,Q14739,Q06136,O95470,P50897,Q8WWI5,Q15800,P48739,P35610,Q8IV08,O14735,Q16850,Q96G23,O15269,Q9P035,P51648,Q53GQ0,Q5T8D3,P17900,Q9BVG9,Q16836,Q9NZ01,O95674,Q8N2A8,O75845,P38435,Q14534,O15254,Q9UG56,Q9NPH0,O43681,Q6Y1H2,Q709F0,P23786,Q9NZJ7,P37268,Q15165,Q92604,Q9H1P3,O43808,Q12770,Q9UBM7,Q8NBJ7,Q8NAN2,P04062,P10619,Q10713,Q16739,P50416,P27544,Q86UL3,P07602,Q9NQZ5,Q16880,Q13510,Q8NBQ5,Q53H12,P04035,P09960 71
Glycerophospholipid biosynthesis 0.678265487558039 3.838136319882408 0.0001239716560275 0.1589256028873149 0.0374795591124259 36 Q9HCL2,Q8WUK0,Q8NF37,Q9Y6K0,O15228,Q96N66,P40939,Q8WWI5,P48739,Q8IV08,O14735,Q9BVG9,O95674,Q8N2A8,Q9UG56,Q9NPH0,Q92604,Q8NAN2,Q86UL3,Q9NQZ5,P35790,Q53H12 22
Phospholipid metabolism 0.5980953149788567 3.6444297248079343 0.0002679853447598 0.3121315583816346 0.0374795591124259 51 Q9BZF1,Q9NTJ5,Q9HCL2,Q8WUK0,Q8NF37,O15228,Q9Y6K0,Q96N66,P40939,Q9BTU6,Q8WWI5,P48739,Q8IV08,O14735,Q6UWP7,Q9BVG9,O95674,Q8N2A8,Q9UG56,Q9NPH0,Q92604,Q8NAN2,Q10713,Q8NCE2,Q9NQZ5,Q86UL3,P35790,Q53H12 28
Protein localization 0.5404429759016612 3.594140601330828 0.0003254640572851 0.3651850735371039 0.0374795591124259 79 O75431,Q99595,P50402,P12236,Q15067,Q9Y512,Q8N4H5,O15228,Q13190,P46379,Q8NBU5,P40855,P39210,P09601,Q9NR77,P12235,Q3ZCQ8,Q9NS69,P56589,P62072,P21796,Q9Y276,P51648,Q5T8D3,Q8TB36,P28288,Q9NX63,O15254,O43681,Q13505,Q9Y5J6,O96011,O43808,O75381,O96008,O14925,O14975,Q9Y3D6,Q9UJS0,Q10713,O95169,O43615,Q96DA6,Q15388,O75746 45
Sphingolipid metabolism 0.7068182307431328 3.5528355425688343 0.0003811026393816 0.4126419547801463 0.0374795591124259 29 Q8NBJ7,P04062,P10619,Q16739,Q96G23,P27544,O43681,P07602,Q16880,P51648,Q9NZJ7,Q13510,P17900,Q06136,O95470 15
Slc mediated transmembrane transport 0.7553134911095359 3.477694944724833 0.0005057451407961 0.5064834130912256 0.0374795591124259 23 Q8WWI5,Q9UBX3,Q9H2J7,P12236,Q8TB61,P05141,P35613,P12235,Q9Y6M7,Q15043,Q70HW3,Q8TAD4,P30825,Q96QD8 14
Glycosphingolipid metabolism 0.7762098203164106 3.322611298608172 0.0008917908694436 0.7122017304071875 0.0374795591124259 17 Q8NBJ7,P04062,P10619,Q16739,P07602,O43681,Q9NZJ7,Q13510,P17900 9
Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins 0.5318067321248132 3.3008048402760206 0.0009640791783096 0.7398517726846381 0.0374795591124259 70 O95298,O96000,Q9Y6M9,O14949,Q9Y6N1,O43676,P03886,Q86Y39,Q9NPL8,P00403,Q9P0J0,P24539,Q8N8Q8,Q9Y375,O75964,P56385,P13073,P03915,P00846,P21912,P56134,O75306,P36542,Q9UDW1,Q9NX14,O75880 26
Mitochondrial protein import 0.5853360482523016 3.1327595407882733 0.0017317124839451 0.911039802580584 0.0447679745849512 37 Q9Y5J9,O75431,Q99595,P12236,Q9Y512,Q8N4H5,P12235,Q3ZCQ8,Q9NS69,P62072,P21796,Q9Y276,Q9NX63,Q13505,Q9Y5J6,O96008,O14925,Q9UJS0,Q10713,O95169,O43615,Q96DA6,Q15388,O75746 24
Mitochondrial calcium ion transport 0.732036324929813 3.0671711426697055 0.0021609509406752 0.9511964231816052 0.0486562502126234 17 Q10713,Q9BPX6,Q9Y277,P45880,O95202,Q8WWC4,P21796,Q9H300 8
Cristae formation 0.7028594160771036 3.039977861760362 0.0023659553903074 0.9633663156595182 0.049918028010082 21 Q9BUR5,Q5XKP0,P00846,O75964,Q6UXV4,P56385,P56134,Q9Y512,P24539,P36542,Q13505,Q9NVH1 12
Respiratory electron transport 0.5210884371863829 3.016918462149901 0.0025535848958733 0.971826227681684 0.0516638335454949 59 O95298,O96000,Q9Y6M9,O14949,Q9Y6N1,O95139,O43676,P03886,Q86Y39,Q9NPL8,Q16134,P00403,Q9P0J0,Q8N8Q8,P20674,Q9BQ95,O00483,Q9Y375,P13073,P03915,P21912,O75306,O43819,O95169,Q9UDW1,Q9NX14,P51970,O75880 28
Asparagine n linked glycosylation 0.4272931594575038 3.012219291775298 0.0025934517234 0.973355205640471 0.0517208372266646 130 Q9UJW0,Q9H3H5,P24390,Q10469,Q9BV10,O60858,O15020,Q11206,Q9BVK6,P04843,Q13190,Q9Y3B3,O75352,Q96AA3,O75935,P46977,Q86YN1,O75340,Q14789,Q9H0U4,P49755,Q86SQ9,O14653,Q96PC5,Q16706,Q9BT22,P62820,Q9GZP9,Q9UKV5,Q15363,Q13561,Q2TAA5,Q9Y6Y8,O43731,Q9H0U3,P10619,P27824,P15291,Q9UBV2,P49257,O95249,Q5JRA6,P53634,O15498 44
Ion channel transport 0.6089015645088773 2.854096589659958 0.0043159406968857 0.997613894239372 0.075313165160657 29 Q93050,P23634,P51798,P51790,Q9Y487,Q15904,P27105,Q9HD20,P05023,Q96PU5,P20020,Q12797,Q4KMQ2,P98194,Q9C0H2,P16615 16
Diseases associated with n glycosylation of proteins 0.8245353591820264 2.714786764806091 0.0066318456266551 0.9999075545578084 0.0952018144805679 10 Q96AA3,Q9H3H5,Q9BT22,P15291,Q10469,Q9BV10,O75340,Q2TAA5 8
Class i peroxisomal membrane protein import 0.7705586942875059 2.638618634076365 0.0083244568308715 0.9999914500136152 0.1066141443660249 12 Q8NBU5,P40855,P28288,O43808,O75381,O96011,Q9NR77,P56589,Q8TB36,P51648,Q5T8D3 11
Diseases of glycosylation 0.5932595349292293 2.6138922774609927 0.008951725552128 0.999996465285526 0.11058945903337 27 O43505,Q96AA3,Q9H3H5,Q86SQ9,Q9BT22,Q8NCH0,P10619,Q10469,Q9BV10,P15291,O75340,Q2TAA5,O75352 13
Glycosaminoglycan metabolism 0.6521319616545957 2.5834993941076903 0.0097803638896138 0.9999989004330092 0.1187251129556608 17 O43505,P15586,Q8NCH0,P15291,Q8TB61,Q11206,P08236,Q7LGA3 8
Transport of inorganic cations anions and amino acids oligopeptides 0.7551678398843671 2.5586211746735796 0.0105088188556961 0.9999996064033866 0.1236644121151424 12 Q9UBX3,Q9H2J7,Q70HW3,P30825,Q96QD8 5
The citric acid tca cycle and respiratory electron transport 0.4063857129849509 2.557538333541079 0.010541593869414 0.9999996241891532 0.1236644121151424 101 O95298,O96000,Q9Y6M9,O14949,Q9Y6N1,O43676,Q13423,P03886,Q86Y39,Q9NPL8,P00403,Q9P0J0,P24539,Q8N8Q8,P21796,Q9Y375,O75964,P56385,P13073,P35613,P03915,P00846,P21912,P56134,O75306,P36542,Q9UDW1,Q9NX14,O75880 29
Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein 0.5996541070233374 2.5521917339582076 0.0107047591382494 0.9999997014726604 0.1245320313083016 25 Q96AA3,Q9H3H5,Q9BT22,P10619,Q9BV10,Q86YN1,Q11206,O75340,Q2TAA5,O75352 10
Cargo concentration in the er 0.6419425548847676 2.529416071918889 0.0114252495539137 0.999999892035432 0.1296719380265336 18 P49755,Q96PC5,O14653,Q5JRA6,O75396,Q15363,Q9Y6B6,P53634,Q13190,P49257 10
Ire1alpha activates chaperones 0.5882630650988169 2.5219483483464633 0.0116706843515668 0.9999999236618168 0.1313893173773167 26 O14773,O14653,P43307,O95070,Q9Y5M8 5
Pink1 prkn mediated mitophagy 0.782448985527146 2.427567617880113 0.0152004530404548 0.9999999994828878 0.1560281797387861 9 Q9NS69,Q8N4H5,P21796,O96008 4
Gamma carboxylation hypusine formation and arylsulfatase activation 0.763657617631736 2.4152333407327853 0.0157251320993006 0.9999999997542526 0.1602356526322893 10 O60725,P38435,Q8NBJ7 3
Synthesis of pa 0.7397709573245999 2.3775787727498416 0.0174267203526239 0.9999999999780482 0.1701237874983427 11 Q8N2A8,Q9HCL2,Q86UL3,Q9NPH0,Q8NF37,O15228 6
Mitochondrial biogenesis 0.5078012370714232 2.3623511803889743 0.0181594308035568 0.999999999992252 0.1760455930678151 34 Q9BUR5,Q5XKP0,P00846,O75964,Q6UXV4,P56385,P56134,Q9Y512,P00367,P24539,P36542,Q16891,Q13505,Q9NVH1 14
Synthesis of very long chain fatty acyl coas 0.7825136200327011 2.3514710743246665 0.0186993434453199 0.9999999999964048 0.176380293578829 8 Q9P035,Q9NZ01,Q53GQ0 3
Metabolism of steroids 0.4802505237150723 2.335434682511275 0.0195207243769477 0.999999999998883 0.1828921559075103 42 Q15800,Q12770,Q9UBM7,O00767,O75845,P38435,P04062,P37268,Q9HCL2,Q15392,Q14534,Q16850,Q53GQ0,Q8NBQ5,P04035,Q14739,Q9H1P3 17
Mitophagy 0.6893746727566857 2.3100919872717407 0.0208830619612678 0.9999999999998396 0.1943516966528664 13 Q9NS69,Q8N4H5,P21796,O96008 4
Complex i biogenesis 0.4997267402545852 2.292027280078764 0.0219040690490091 0.9999999999999626 0.2011715815290572 34 Q9NPL8,Q9Y375,O95298,P51970,O96000,O75306,Q9Y6M9,Q9P0J0,P03915,O95169,O95139,O43676,Q9NX14,P03886,Q86Y39,Q9BQ95 16
Gpcr ligand binding 0.7491651778742864 2.263661098472055 0.0235949668615125 0.9999999999999968 0.2045874145259098 9 P07602,Q9NZJ7,P63218 3
Stimuli sensing channels 0.7445352955628586 2.2406024164230405 0.0250518400553745 0.9999999999999996 0.2101936052232421 9 P51798,P51790,P27105,Q96PU5,Q12797,Q4KMQ2,Q9C0H2 7
Cholesterol biosynthesis 0.6184135423979031 2.2391687702265513 0.0251449370145282 0.9999999999999996 0.2101936052232421 16 Q15800,Q9UBM7,O75845,Q14739,Q14534,Q15392,Q16850,P04035,P37268 9
Processing of smdt1 0.6845345487825398 2.181073929727515 0.0291779487577399 1.0 0.2328624848853624 12 Q99623,Q10713,Q9BPX6,Q8WWC4,Q9H300 5
Intra golgi and retrograde golgi to er traffic 0.3978626709427129 2.1767699046606466 0.0294977395811935 1.0 0.2328874775689189 91 Q9UJW0,P24390,Q8TBA6,Q9BVK6,O60499,Q13190,Q9Y3B3,Q96JB2,O75935,Q8N2H4,Q9H0U4,P49755,O14653,Q16706,P62820,Q15363,Q13561,O00461,Q9P2W9,Q07866,Q9H0B6,O43731,O15498,O95249,Q12981,O15260,Q10472 27
O linked glycosylation 0.7463970944448912 2.1763647581639325 0.0295279967977784 1.0 0.2328874775689189 8 Q11206,Q8N4A0,Q10472,Q9H5K3 4
Rhoa gtpase cycle 0.4544790925983714 2.1672062312329525 0.0302191324715512 1.0 0.2369994883723909 45 P41440,Q14155,Q96CS3,P51572,O15173,Q15904,P30519,P49257,Q8TAA9,P42167,Q5T8D3,Q14739,O15498 13
Miscellaneous transport and binding events 0.741259450600351 2.1511573434362785 0.0314637826424706 1.0 0.2453823495468659 8 Q9H0U3,Q9UNS2,Q9HD23,Q8N4V1 4
Vitamin d calciferol metabolism 0.9383604505632082 2.1201031821184317 0.0339973446704449 1.0 0.2591011731295513 2 P04062 1
Amino acid transport across the plasma membrane 0.8874964169749165 2.1182857946141644 0.0341508709569036 1.0 0.2591011731295513 5 P30825,Q96QD8 2
Intra golgi traffic 0.6473014053580325 2.07258215200098 0.0382111834840757 1.0 0.2735528827885625 13 O14653,Q16706,Q8TBA6,O95249,O00461,Q13190,O15498 7
Maturation of protein 3a 0.9208385481852336 2.0434131918345786 0.041011552677499 1.0 0.2862606376889431 2 Q11206 1
Heme degradation 0.9034302198413314 2.028169816046566 0.0425429193714244 1.0 0.2940094823886558 4 P09601 1
Formation of atp by chemiosmotic coupling 0.6727865045664451 2.023613931070916 0.0430098905164464 1.0 0.2945375586570091 11 P00846,O75964,P56385,P24539,P36542 5
Ion transport by p type atpases 0.6559494723134037 2.023308946031138 0.0430413051332592 1.0 0.2945375586570091 12 Q9HD20,P05023,P20020,P98194,P16615 5
Rab geranylgeranylation 0.5369243336320648 2.0091423958005628 0.0445220346283445 1.0 0.3017124288406264 23 Q969Q5,P61026,P53611,Q9H0U4,P62820,Q6IQ22,P61019,O14966 8
Rhod gtpase cycle 0.492842142243692 2.002274298174979 0.045255238677482 1.0 0.3046315424450436 30 P50402,O15173,P49257,Q9Y6M7,Q8TAA9,P42167,Q86Y07,Q14739 8
Abacavir transport and metabolism 0.9083229036295368 1.9883682484129064 0.0467709777504192 1.0 0.3094421087184137 2 P49902 1
Transport to the golgi and subsequent modification 0.3948396387639059 1.980260522371761 0.0476742623015351 1.0 0.3109965895931919 83 Q9UJW0,P24390,Q10469,O15020,Q11206,Q9BVK6,Q13190,Q9Y3B3,Q96JB2,O75935,Q14789,O15027,P49755,Q9H0U4,O14653,Q96PC5,Q16706,P62820,O75396,Q15363,Q13561,Q9Y6B6,Q9Y6Y8,O43731,P15291,P49257,O95249,Q5JRA6,P53634,O15498 30
Selective autophagy 0.4891593484906355 1.9714226187477115 0.0486755559818321 1.0 0.3158030459823482 30 O96008,Q9NS69,Q8N4H5,P21796,P08670 5
O linked glycosylation of mucins 0.8060749348867788 1.9676570078752156 0.0491075156346758 1.0 0.3158030459823482 6 Q11206,Q8N4A0,Q10472 3
Incretin synthesis secretion and inactivation 0.8864975841472884 1.9587671511222065 0.0501400622031433 1.0 0.3158030459823482 4 P67812 1
Synthesis secretion and inactivation of glucagon like peptide 1 glp 1 0.8864975841472884 1.9587671511222065 0.0501400622031433 1.0 0.3158030459823482 4 P67812 1
Copi mediated anterograde transport 0.4232582477268518 1.9549740981374744 0.0505861275832129 1.0 0.3158030459823482 53 P49755,Q9UJW0,O43731,O14653,P24390,O75935,P62820,O15020,Q9BVK6,Q15363,Q13561,O95249,Q13190,Q9Y3B3,Q14789,O15498,Q9H0U4 17
Peptide hormone metabolism 0.6259832019232032 1.9496875234023132 0.0512133742938625 1.0 0.3158030459823482 13 P67812,Q8TAD4 2
Pre notch processing in golgi 0.847478860006252 1.9492436654268304 0.0512663326173361 1.0 0.3158030459823482 5 Q11206,Q15363,Q9UBV2,P16615 4
Metabolism of porphyrins 0.6718643584672379 1.9419762164562544 0.0521399795848369 1.0 0.3158030459823482 10 P09601,Q7KZN9,P30519,P22830 4
The activation of arylsulfatases 0.894868585732164 1.9289590016693672 0.0537359521321803 1.0 0.3158030459823482 2 Q8NBJ7 1
Metal ion slc transporters 0.8939299123904989 1.9248053636735032 0.0542537127353097 1.0 0.3158030459823482 2 Q8TAD4 1
Zinc transporters 0.8939299123904989 1.9248053636735032 0.0542537127353097 1.0 0.3158030459823482 2 Q8TAD4 1
Transport of vitamins nucleosides and related molecules 0.796015502899069 1.922883854797298 0.0544946378245334 1.0 0.3158030459823482 6 P12236,Q8TB61,P12235 3
Sphingolipid de novo biosynthesis 0.6374575868654637 1.919713077284927 0.0548941514959084 1.0 0.3158030459823482 12 P27544,Q96G23,P51648,Q06136,O95470 5
Unfolded protein response upr 0.4347997951123689 1.918385045693198 0.0550622058247363 1.0 0.3158030459823482 43 O14773,O14653,P43307,O95070,Q9Y5M8 5
Acyl chain remodelling of pg 0.8914267834793579 1.913723516864133 0.0556554925566172 1.0 0.3158030459823482 2 Q8NF37 1
Transport of bile salts and organic acids metal ions and amine compounds 0.8302536799248295 1.8756214327181513 0.0607072812390692 1.0 0.3297562825281736 5 Q15043,Q9H2J7,P35613,Q8TAD4 4
Initiation of nuclear envelope ne reformation 0.5368809167289286 1.863981330177006 0.0623243262040495 1.0 0.3308405736608439 19 P50402,Q86XL3,P42167,Q8IXJ6,Q14739 5
Arachidonate production from dag 0.8726533166458241 1.8303648647578157 0.0671953979026078 1.0 0.347425094340891 2 Q8NCG7 1
Synthesis of pc 0.6745746965257751 1.8172634471309088 0.0691767840756654 1.0 0.351166511162287 8 Q9NQZ5,Q8NF37,Q8WWI5,Q9Y6K0 4
Nuclear envelope ne reassembly 0.4113807807200746 1.810019562738025 0.0702927535148507 1.0 0.3555387098069987 48 P50402,Q8NFH5,Q86XL3,P42167,Q86Y07,Q9BTX1,Q8IXJ6,Q7Z3B4,Q14739 9
Synaptic adhesion like molecules 0.8121841447954417 1.797857885261562 0.0721995314958952 1.0 0.3612564371622569 5 O95197 1
Rac2 gtpase cycle 0.4348712943776125 1.7952826202806211 0.0726086826425032 1.0 0.3620061463176231 37 P50402,O15173,Q86XL3,P49257,Q9Y512,Q8TAA9,P42167,Q13505,Q14739 9
Peptide ligand binding receptors 0.757592920066642 1.7500549982813236 0.0801088239758209 1.0 0.3834937710288165 6 P07602,Q9NZJ7 2
Class a 1 rhodopsin like receptors 0.757592920066642 1.7500549982813236 0.0801088239758209 1.0 0.3834937710288165 6 P07602,Q9NZJ7 2
Synthesis of pg 0.8359423919849667 1.7490125073040743 0.0802888574611717 1.0 0.3834937710288165 4 Q8IV08,Q8N2A8,O95674 3
N glycan antennae elongation 0.8466833541927561 1.7144049239101704 0.086454384854151 1.0 0.3962677933543367 2 Q11206 1
Post translational modification synthesis of gpi anchored proteins 0.6513061506954071 1.6978959502443929 0.0895274017535086 1.0 0.3987682440716465 8 Q5H8A4,O43292,Q9H490 3
Ras processing 0.7777377820610583 1.6481968188679568 0.0993122894187834 1.0 0.4239754006991489 5 O60725,P49356 2
Rnd1 gtpase cycle 0.5090856730655493 1.6403769539399804 0.1009268140826264 1.0 0.4282487308794729 17 O43396,P51648 2
Organic anion transporters 0.8197747183980197 1.5936079289326035 0.1110238774755729 1.0 0.4544372932688971 2 Q9UBX3 1
Sialic acid metabolism 0.7230207222925271 1.592240723098443 0.111330626287939 1.0 0.4544372932688971 6 Q11206 1
Er to golgi anterograde transport 0.3714205462466234 1.5901193991520004 0.1118078940201561 1.0 0.4550548689566703 77 Q9UJW0,P24390,O15020,Q9BVK6,Q13190,Q9Y3B3,Q96JB2,O75935,Q14789,O15027,P49755,Q9H0U4,O14653,Q96PC5,P62820,O75396,Q15363,Q13561,Q9Y6B6,Q9Y6Y8,O43731,P49257,O95249,Q5JRA6,P53634,O15498 26
Synthesis secretion and inactivation of glucose dependent insulinotropic polypeptide gip 0.8935050588819073 1.5830055296403742 0.1134202040482015 1.0 0.4566508947398971 3 P67812 1
Synthesis secretion and deacylation of ghrelin 0.8935050588819073 1.5830055296403742 0.1134202040482015 1.0 0.4566508947398971 3 P67812 1
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane 0.7960719129734372 1.5811855870537364 0.1138356098635273 1.0 0.4566508947398971 4 P12236,P12235 2
Copi dependent golgi to er retrograde traffic 0.3889162266854932 1.5711198580247818 0.1161548107931169 1.0 0.4598901629542497 50 P49755,Q9H0B6,P24390,P62820,Q9BVK6,Q12981,Q9P2W9,Q9Y3B3,O15260,Q9H0U4 10
Peroxisomal lipid metabolism 0.5548976647298722 1.5278328740291762 0.1265540379046827 1.0 0.4753485624952546 13 Q15067,Q5T8D3,P51648,O15254 4
N glycan antennae elongation in the medial trans golgi 0.7472630775243936 1.514405272307911 0.1299230828937485 1.0 0.4836603299191279 5 Q11206,P15291,Q10469 3
Er quality control compartment erqc 0.746895953736238 1.5127865241086964 0.1303338929386326 1.0 0.4838992408040721 5 Q9GZP9,Q9UBV2,O60858 3
Hs gag biosynthesis 0.7984981226533377 1.4977667704069175 0.1341938571108629 1.0 0.4930369218724056 2 Q7LGA3 1
Bmal1 clock npas2 activates circadian gene expression 0.7981852315394414 1.4963558952419191 0.1345609364135782 1.0 0.4930369218724056 2 P43490 1
Rora activates gene expression 0.798185231539422 1.496355895241833 0.1345609364136006 1.0 0.4930369218724056 2 P50416 1
Conversion from apc c cdc20 to apc c cdh1 in late anaphase 0.6068410772297694 1.4660250196277655 0.1426414708579477 1.0 0.5145413264023129 8 Q96DE5,Q9UJX5,Q12834,Q9UJX2,P30260 5
Heparan sulfate heparin hs gag metabolism 0.6918549770374816 1.448342524761736 0.1475212802933667 1.0 0.5244965876716763 6 P08236,Q7LGA3 2
Ptk6 regulates proteins involved in rna processing 0.7862953692115116 1.442723693412671 0.1490983220610857 1.0 0.5251930080231655 2 Q07666 1
Small interfering rna sirna biogenesis 0.785982478097619 1.4413119500097855 0.1494965727638675 1.0 0.5251930080231655 2 Q15631 1
Attachment of gpi anchor to upar 0.726468321603049 1.4224891795776329 0.1548842904952669 1.0 0.5340143114711955 5 Q92643,O43292,Q9H490 3
Maturation of sars cov 2 spike protein 0.5371307901134339 1.4197158601282602 0.1556904188888084 1.0 0.5340143114711955 13 Q9H0U3,Q16706,P27824,Q10469,P46977,Q11206 6
Organelle biogenesis and maintenance 0.3419670917423658 1.4102113460720396 0.158477286568871 1.0 0.5402148060797115 91 O75431,Q9Y512,Q16891,Q9BUR5,Q5XKP0,Q6UXV4,O75935,P24539,Q9NVH1,Q7Z4L5,O75964,P56385,P00367,A0AVF1,Q13505,P00846,P56134,Q10713,P36542,Q9H6D7 20
Interleukin 4 and interleukin 13 signaling 0.5333628993639586 1.396666296220357 0.1625139438882663 1.0 0.5474666801775603 13 P09601,Q07820,P08670 3
Insertion of tail anchored proteins into the endoplasmic reticulum membrane 0.5685148141668638 1.378691515756069 0.1679898864890612 1.0 0.5545233879990928 10 P50402,P09601,O43681,P51648,Q13190 5
Keratan sulfate biosynthesis 0.8403755868544613 1.3684995147412429 0.1711557737897153 1.0 0.559012396348886 3 Q11206,P15291 2
Copii mediated vesicle transport 0.3932899991574997 1.3637531779495868 0.1726452611126518 1.0 0.5604948477052606 35 P49755,O14653,P62820,O95486,Q9HCU5,P49257,O75396,O15027,Q15363,Q9Y6B6,Q9Y6Y8,Q13190,P55735,P53634,O15498,Q9H0U4 16
Cytochrome p450 arranged by substrate type 0.8388215531236444 1.362212665423115 0.1731307798880133 1.0 0.5607669807973702 3 Q16850 1
Effects of pip2 hydrolysis 0.8375558084269488 1.3570919597749402 0.1747519928652519 1.0 0.5634036536718052 3 Q8NCG7 1
Noncanonical activation of notch3 0.766583229036292 1.3537819441855437 0.1758059557790146 1.0 0.5654956549942497 2 P67809 1
Cytosolic sulfonation of small molecules 0.7418011315953494 1.3502024133112127 0.1769510643047085 1.0 0.5655968811180101 4 Q9NX62 1
Inflammasomes 0.7411583509765152 1.3474547715430665 0.1778338106574706 1.0 0.5655968811180101 4 P09601 1
The nlrp3 inflammasome 0.7411583509765152 1.3474547715430665 0.1778338106574706 1.0 0.5655968811180101 4 P09601 1
Signaling by retinoic acid 0.5611504508649927 1.3374988719780316 0.1810598502374369 1.0 0.5692782678636532 10 Q15118,P50416,Q9HBH5,Q8NBN7 4
Keratan sulfate keratin metabolism 0.623555399284295 1.3315165186867688 0.1830191133408552 1.0 0.5741453533119862 7 O43505,P15291,Q11206 3
Platelet calcium homeostasis 0.7049447881870196 1.3269425454264707 0.1845276890865501 1.0 0.5764291549797554 5 P20020,P23634,P16615 3
Linoleic acid la metabolism 0.7603254067584444 1.3255588605700634 0.1849858606238756 1.0 0.5764291549797554 2 O95864 1
Synthesis of pe 0.8282212545797283 1.319327135138379 0.1870597699044558 1.0 0.5803009750813785 3 Q9UG56 1
Translation of sars cov 2 structural proteins 0.4562986412548604 1.3104709370349703 0.1900365697810397 1.0 0.5807278174352807 20 Q9H0U3,Q16706,P27824,Q10469,P46977,Q11206,Q10472,P49841 8
Rac3 gtpase cycle 0.3865824814743697 1.3102557801352377 0.1901093213237272 1.0 0.5807278174352807 36 P50402,O15173,P49257,Q8TAA9,P42167,Q86Y07,Q14739 7
G protein activation 0.7534418022528412 1.294530496005043 0.1954822425406301 1.0 0.5843537699929758 2 P63218 1
Inwardly rectifying k channels 0.7534418022528412 1.294530496005043 0.1954822425406301 1.0 0.5843537699929758 2 P63218 1
Potassium channels 0.7534418022528412 1.294530496005043 0.1954822425406301 1.0 0.5843537699929758 2 P63218 1
Presynaptic function of kainate receptors 0.7534418022528412 1.294530496005043 0.1954822425406301 1.0 0.5843537699929758 2 P63218 1
Glucagon type ligand receptors 0.7534418022528412 1.294530496005043 0.1954822425406301 1.0 0.5843537699929758 2 P63218 1
Prostacyclin signalling through prostacyclin receptor 0.7534418022528412 1.294530496005043 0.1954822425406301 1.0 0.5843537699929758 2 P63218 1
Synthesis of substrates in n glycan biosythesis 0.4568490458707757 1.2709489033969188 0.2037468271098859 1.0 0.6026071411978828 18 Q11206,Q86YN1 2
Ra biosynthesis pathway 0.8140845070422507 1.2621508204343312 0.2068945212699589 1.0 0.6067746884303836 3 Q9HBH5,Q8NBN7 2
Cd28 dependent pi3k akt signaling 0.7443679599499403 1.2536687531654944 0.2099624298309887 1.0 0.6081842181646604 2 P31751 1
Rhog gtpase cycle 0.3767143061739104 1.2525386963831728 0.2103736370892766 1.0 0.6081842181646604 39 P50402,O15173,Q86XL3,P49257,Q8TAA9,P42167,O95202,Q86Y07,Q14739,O15498 10
Iron uptake and transport 0.4532177905942752 1.2446762601356878 0.2132507757607249 1.0 0.6117432071421388 18 Q93050,P09601,Q9Y487,Q658P3,P30519 5
Transcriptional regulation by ventx 0.5415215403299316 1.2272000419587632 0.2197474136761965 1.0 0.6202961491037339 10 P04637,Q96DE5,Q9UJX5,Q9UJX2,P30260 5
Reduction of cytosolic ca levels 0.7108840582149903 1.217911740814382 0.2232575140671042 1.0 0.6241422989168013 4 P20020,P16615 2
Post translational protein modification 0.2825812013395202 1.1939721929953693 0.2324888455398381 1.0 0.6326700078714522 409 O43505,P24390,O60858,O15020,P45880,Q6IQ22,Q13190,Q7Z3B4,P61019,O75352,Q70CQ2,P46977,Q86YN1,Q7Z434,Q9Y277,P21796,Q9H5K3,Q86SQ9,O14653,Q16706,Q969V5,Q14166,O60725,Q13561,Q9Y6Y8,Q02818,P04439,O43731,Q92905,Q86VX2,P28072,Q5JRA6,Q13636,P53634,Q969Q5,Q9H3H5,Q9UJW0,Q11206,P04843,P61978,Q96JB2,Q9UPU5,Q5H8A4,Q13546,Q96AA3,Q12834,Q9NZL9,Q96GG9,O94952,Q9H490,P38435,Q96PC5,Q9BT22,Q8NBJ7,P10619,Q9UBV2,O95249,Q10472,Q9UNS2,O43292,Q9BV10,P49721,Q07065,Q9BVK6,Q9Y3B3,O75340,P28074,Q9BTX1,O14966,P49755,Q7L5N1,P62820,Q9GZP9,O43681,P61026,O75381,Q9H0U3,P49257,Q8NFH5,Q8N4A0,Q10469,Q9BTY2,O75935,P51784,Q14789,O15504,Q9H0U4,Q12769,O43852,Q9UKV5,Q15363,Q92643,Q2TAA5,O00487,P53611,P27824,P15291,P43686,O15498 99
Cardiac conduction 0.4869624048920741 1.19049412472607 0.2338522378665253 1.0 0.6326700078714522 14 Q13586,P23634,P05023,P20020,P16615 5
Ion homeostasis 0.4869624048920741 1.19049412472607 0.2338522378665253 1.0 0.6326700078714522 14 Q13586,P23634,P05023,P20020,P16615 5
Platelet homeostasis 0.4701787355129432 1.1677698978444415 0.2428995934530391 1.0 0.6490657702353912 15 Q13586,P23634,Q16537,Q99487,P63218,P20020,P16615 7
Basigin interactions 0.6598327696483877 1.1259957237729867 0.2601673293557962 1.0 0.6639736595625074 5 P35613,P54709 2
Abc transporters in lipid homeostasis 0.7799687010954477 1.1245098131052005 0.2607968098601683 1.0 0.6643655959211586 3 P40855,P56589 2
Wax and plasmalogen biosynthesis 0.6883529004764092 1.1215218486730207 0.262065796714928 1.0 0.6651706403891627 4 O15228,Q6IAN0 2
Tp53 regulates metabolic genes 0.3685041275851956 1.1197456220282025 0.2628221777223658 1.0 0.6655711824452754 35 P31751,P00403,P13073,O43819,Q9Y6N1,Q8N8Q8,O75880 7
Translation of sars cov 1 structural proteins 0.541201635390007 1.1166954297646248 0.2641245726192691 1.0 0.6655711824452754 8 Q11206,P27824,Q10472 3
Fatty acyl coa biosynthesis 0.4624881951436578 1.1164283366522132 0.264238829672371 1.0 0.6655711824452754 15 P50897,O00767,Q9P035,Q53GQ0,Q9NZ01 5
Bicarbonate transporters 0.7124530663329407 1.1105670460706571 0.2667547539737471 1.0 0.6655711824452754 2 Q9Y6M7 1
Transport of connexons to the plasma membrane 0.685660613650598 1.110017918289364 0.266991305278903 1.0 0.6655711824452754 4 Q9BUF5,Q13885,P17302 3
Gap junction assembly 0.685660613650598 1.110017918289364 0.266991305278903 1.0 0.6655711824452754 4 Q9BUF5,Q13885,P17302 3
Carboxyterminal post translational modifications of tubulin 0.6856606136505959 1.1100179182893546 0.266991305278907 1.0 0.6655711824452754 4 Q9BUF5,Q13885,Q14166 3
Alpha oxidation of phytanate 0.6509688769412 1.0865194644510252 0.2772492341663208 1.0 0.6756960843156313 5 O43808,P51648 2
Fatty acid metabolism 0.3440925008235841 1.0774810257150766 0.2812654230600799 1.0 0.6793192570793627 57 P50897,O00767,Q15165,O15254,Q15067,Q9P035,Q6Y1H2,Q709F0,Q9H7Z7,Q53GQ0,Q5T8D3,P51648,P23786,P40939,Q16836,Q9NZ01,P09960 17
Response to elevated platelet cytosolic ca2 0.3775846700064781 1.075908297262368 0.2819682707595976 1.0 0.6798405975481836 32 Q8NBM8,O43852,Q6UXV4,P13473,Q96JJ7,Q9UHQ9,P07602,Q8NBX0,Q9NZJ7,Q9Y6I9,Q92520,O94919 12
Vitamin c ascorbate metabolism 0.7033792240300522 1.0701459171778451 0.2845536336180108 1.0 0.6825375816679434 2 P78417 1
Chylomicron assembly 0.7024405506883544 1.0659731942800803 0.2864357595220261 1.0 0.6858736197131192 2 Q9Y6B6 1
Apc cdc20 mediated degradation of nek2a 0.512487285020298 1.0630697127637576 0.2877503382711688 1.0 0.6866657644898319 10 Q96DE5,Q9UJX5,Q12834,Q9UJX2,P30260,O60566 6
Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components 0.512487285020298 1.0630697127637576 0.2877503382711688 1.0 0.6866657644898319 10 Q96DE5,Q9UJX5,Q12834,Q9UJX2,P30260,O60566 6
Endosomal vacuolar pathway 0.6732021094914432 1.0568501199340534 0.2905799960480573 1.0 0.6887091247590628 4 Q9UIQ6,P04439 2
Sars cov 2 infection 0.3953353182740352 1.0325504398215832 0.3018143313911188 1.0 0.6998883830930263 27 Q9H0U3,Q16706,P27824,Q10469,P46977,Q11206,Q10472,P49841 8
Rnd2 gtpase cycle 0.4221874152588764 1.0186859559203756 0.3083520820756003 1.0 0.7079926095025295 18 O43396,P51648,Q07065 3
Mucopolysaccharidoses 0.6613093887309693 1.006232974563427 0.3143035136159282 1.0 0.7166575333335727 4 P08236,P15586 2
Pexophagy 0.6880475594493052 1.0022293469535504 0.3162328370583664 1.0 0.7166575333335727 2 P50542 1
Nrif signals cell death from the nucleus 0.688047559449305 1.0022293469535486 0.3162328370583673 1.0 0.7166575333335727 2 Q92542 1
Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways 0.4914763271954201 0.9977596540549551 0.3183959186122405 1.0 0.7192244375124397 11 P09601 1
Slc transporter disorders 0.3728301840456913 0.9935782284138642 0.3204282479081062 1.0 0.7203185733972887 31 Q8NFH5,P35613,Q9BTX1,Q7Z3B4,O15504 5
Sulfide oxidation to sulfate 0.7419805001964307 0.9725933437014376 0.3307554521638476 1.0 0.7278668602174612 3 Q9UBX3 1
Golgi to er retrograde transport 0.328466327418563 0.965364074592729 0.3343624888927761 1.0 0.7293374635474078 71 P49755,Q9UJW0,Q9H0B6,O43731,P24390,O75935,P62820,Q9BVK6,Q15363,Q13561,Q12981,Q9P2W9,Q9Y3B3,Q07866,O15260,Q10472,Q9H0U4 17
Activation of gene expression by srebf srebp 0.426590927306879 0.9596850901406035 0.3372137294585324 1.0 0.7315383112711665 16 O75845,O00767,Q14534,Q9HCL2,P04035,P37268 6
Class b 2 secretin family receptors 0.7377667021113713 0.955883034517389 0.3391313312080695 1.0 0.7315383112711665 3 P63218 1
Heme biosynthesis 0.585493710855234 0.9511727154131944 0.3415167066151772 1.0 0.7315383112711665 6 Q7KZN9,P22830 2
Biological oxidations 0.3419595343646636 0.9506706838565654 0.3417715745699086 1.0 0.7315383112711665 43 O43169,Q99735,Q8TB61,Q16850,P21964,Q9NX62,P07099 7
Miro gtpase cycle 0.6480901690669886 0.950185572801131 0.3420179680271369 1.0 0.7315383112711665 4 Q8IWA4,Q8IXI1,Q8IXI2 3
Antigen presentation folding assembly and peptide loading of class i mhc 0.412782846351604 0.9498508385660702 0.3421880496132319 1.0 0.7315383112711665 18 Q6P179,P51572,P27824,Q03519,Q9Y6B6,Q9NZ08,P55735,P10321,P04439 9
Pre notch expression and processing 0.4718825898972245 0.9463328440183556 0.3439788463442199 1.0 0.732038314439147 12 Q11206,Q15363,Q9UBV2,P16615 4
Regulation of cholesterol biosynthesis by srebp srebf 0.3920622600826016 0.94195920828457 0.3462135247783342 1.0 0.7334983350423366 25 Q12770,Q9UBM7,O75845,O00767,Q14534,Q9HCL2,Q16850,P04035,P37268 9
Calnexin calreticulin cycle 0.4909573779915827 0.9410672300763592 0.3466704075197655 1.0 0.7334983350423366 10 Q9UKV5,Q9GZP9,Q9UBV2,O60858 4
Reactions specific to the complex n glycan synthesis pathway 0.7323943661971724 0.9346303782138616 0.3499788179089624 1.0 0.7369086422336525 3 Q16706,Q10469 2
Diseases associated with glycosaminoglycan metabolism 0.5804178270849315 0.9275031745073136 0.3536653443288107 1.0 0.7381062570472834 6 Q8NCH0,P15291 2
Rhoc gtpase cycle 0.3699455748000276 0.923558306598577 0.3557163299102486 1.0 0.7381780348899232 30 P41440,P27105,P49257,Q8TAA9,P42167,Q5T8D3,Q13190,Q14739 8
G1 s specific transcription 0.4966486948123342 0.9233773122063804 0.3558106107795171 1.0 0.7381780348899232 9 P04818,P00374,P28749,P31350,P04183 5
Metabolism of steroid hormones 0.6401513961285452 0.9166646271551082 0.3593184073909419 1.0 0.7381780348899232 4 Q53GQ0 1
Cell surface interactions at the vascular wall 0.4554697569595855 0.9137459027018584 0.3608503780835699 1.0 0.7381780348899232 13 P14174,P35613,Q08722,P54709,P05556,Q92896 6
Integrin cell surface interactions 0.637297057866903 0.9046419008251624 0.3656551297398978 1.0 0.7381780348899232 4 Q08722 1
Aflatoxin activation and detoxification 0.6088306871208098 0.8997712171655563 0.3682420147032594 1.0 0.7381780348899232 5 Q99735,O14880 2
Platelet activation signaling and aggregation 0.3287561704422067 0.8922448593518182 0.3722617024086718 1.0 0.7381780348899232 53 Q8NBM8,P63218,O43852,Q6UXV4,P13473,Q96JJ7,Q9UHQ9,P07602,Q8NBX0,Q8NCG7,Q9NZJ7,Q9Y6I9,Q8N2K0,Q92520,O94919 15
G beta gamma signalling through pi3kgamma 0.6292634899252277 0.8708975715825749 0.3838100828685098 1.0 0.749884517507272 4 P31751,P63218 2
Intraflagellar transport 0.4777916472544037 0.8665697340465214 0.3861778026609113 1.0 0.752938844294179 10 Q7Z4L5,Q92973,Q13885,A0AVF1,Q9BUF5 5
N glycan trimming in the er and calnexin calreticulin cycle 0.4003349359513867 0.8627845192914315 0.388255952201435 1.0 0.7548820463415089 17 Q9UKV5,Q9GZP9,Q9UBV2,O60858 4
Interactions of vpr with host cellular proteins 0.3464233189069841 0.8575511407526135 0.3911403641953677 1.0 0.7559336356332731 34 Q12769,Q8NFH5,P12236,P12235,Q9BTX1,Q7Z3B4,O15504 7
Nuclear envelope breakdown 0.3322399830614126 0.8460909898026117 0.3975019867611562 1.0 0.7601544842720194 43 P50402,Q8NFH5,P42167,Q86Y07,Q9BTX1,Q7Z3B4,O15504 7
Protein protein interactions at synapses 0.4422645920398939 0.8315221531204708 0.4056787188241662 1.0 0.7679196627153626 13 O95197 1
Cytoprotection by hmox1 0.3196843788973637 0.8241808061478162 0.4098368313086751 1.0 0.7710676772330328 67 P00403,P09601,P30519,P28072,P13073,P49721,O43819,Q9Y6N1,P28074,Q8N8Q8,P43686,O00487,P20674,O75880 14
Beta oxidation of butanoyl coa to acetyl coa 0.6135303314818219 0.8052769533559992 0.4206598780721926 1.0 0.7840287427531096 4 P40939 1
Nf kb activation through fadd rip 1 pathway mediated by caspase 8 and 10 0.6119462043646995 0.7987086744537802 0.4244593557505736 1.0 0.7869028839269063 4 Q7Z434 1
Activation of kainate receptors upon glutamate binding 0.6970945294309577 0.7967754925531114 0.4255814307770875 1.0 0.7869028839269063 3 P63218 1
Metabolism of folate and pterines 0.4729525394996333 0.7933040049460436 0.4276007240168122 1.0 0.787268551972156 9 Q9H2D1 1
Phase i functionalization of compounds 0.4252627765489549 0.7925348830558868 0.428048860339377 1.0 0.787268551972156 14 O43169,P07099,Q16850 3
Adp signalling through p2y purinoceptor 1 0.6942097026603744 0.7856742696138342 0.4320583411206748 1.0 0.787268551972156 3 Q9UBI6,P63218 2
Signaling by gpcr 0.325932435825698 0.7643428655142342 0.4446629470040431 1.0 0.796509919730426 42 Q14155,P42892,P31751,P07602,Q8NCG7,Q9NZJ7,P63218,Q8N2K0 8
Synthesis of dolichyl phosphate 0.6837464193173972 0.745661427146139 0.4558719658087478 1.0 0.80775750665598 3 Q86YN1 1
Hemostasis 0.2846741423623014 0.7440471607186239 0.4568479442989466 1.0 0.8083139800270335 125 P14174,Q8NBM8,Q9UHQ9,Q8NCG7,Q08722,Q8N2K0,Q6UXV4,P13473,Q8NBX0,Q9Y6I9,Q92520,P20020,O94919,P23634,O43852,Q16537,P35613,Q9NZJ7,P63218,Q07866,P16615,Q9H0B6,Q08380,Q96JJ7,P42785,P07602,Q8IWA4,Q00535,Q92896 29
Autophagy 0.3150436910362221 0.738535996921301 0.4601888010660115 1.0 0.8111408665254447 49 Q7Z3C6,O96008,Q9NS69,Q8N4H5,P21796,P08670 6
Peroxisomal protein import 0.3748366680455819 0.7321178596735836 0.4640966338321755 1.0 0.8169973528748007 22 Q15067,P39210,O15254,O15228 4
Immunoregulatory interactions between a lymphoid and a non lymphoid cell 0.4674001236832512 0.7223038475863076 0.4701076878649552 1.0 0.820337915324347 8 Q5KU26,P10321,P05556,P04439,P15151 5
Activation of ampk downstream of nmdars 0.5912913348262101 0.7138479744784358 0.4753211905986509 1.0 0.8232610199450581 4 Q9BUF5,Q13885 2
Synthesis of pips at the golgi membrane 0.4952443939874887 0.6927733280275231 0.4884518129611892 1.0 0.8326911642047657 7 Q9NTJ5,Q10713 2
Akt phosphorylates targets in the cytosol 0.5840429912695788 0.6844600079172789 0.4936847345145079 1.0 0.8374203748652319 4 P31751 1
Sars cov 1 infection 0.3956583655979983 0.6696327875659575 0.503091907465266 1.0 0.8412895152538675 15 Q11206,P27824,Q10472 3
Constitutive signaling by akt1 e17k in cancer 0.5553562377494036 0.6682081531643926 0.5040007317799038 1.0 0.8412895152538675 5 P31751,P49841 2
Depolymerisation of the nuclear lamina 0.4420578358330732 0.666127379944809 0.5053296851567128 1.0 0.8412895152538675 10 P42167 1
Egr2 and sox10 mediated initiation of schwann cell myelination 0.4493496692547171 0.6651204981032576 0.5059734249253502 1.0 0.8412895152538675 9 P04035,Q9NR77 2
Tp53 regulates transcription of genes involved in g1 cell cycle arrest 0.6063829787234059 0.6545621163305243 0.5127497218383585 1.0 0.8460976497474568 2 P04637 1
Activation of rac1 downstream of nmdars 0.6581838144046265 0.6498147405891306 0.5158118961545801 1.0 0.8484471239489602 3 Q14155 1
Degradation of cysteine and homocysteine 0.5481413079934883 0.6377754764837784 0.5236198454680023 1.0 0.8562166645708887 5 Q9UBX3 1
Tp53 regulates transcription of cell death genes 0.4822356525134792 0.6297670809399821 0.5288469864223919 1.0 0.8584539454019292 7 Q658P3 1
Ros and rns production in phagocytes 0.4490227174443179 0.6260225516892793 0.5313001495187741 1.0 0.8601488476386533 8 Q93050 1
Transferrin endocytosis and recycling 0.4256788585851891 0.6171117703152476 0.5371610056081186 1.0 0.8601488476386533 11 Q658P3,Q93050,Q9Y487 3
Cellular response to chemical stress 0.2952619645107928 0.5839923783980703 0.5592254398014203 1.0 0.8773092165749045 77 Q96HE7,P00403,P09601,P30519,P28072,P13073,P49721,O43819,Q9Y6N1,Q8N8Q8,P28074,Q8TED1,P43686,O00487,P20674,O75880 16
Hs gag degradation 0.6385347119114314 0.5783554787420471 0.563024145529925 1.0 0.8801586866290876 3 P08236 1
Sumoylation of sumoylation proteins 0.3417623759152267 0.5759537554809065 0.5646464396422561 1.0 0.8804050583021084 27 Q7Z3B4,O15504,Q9BTX1,Q8NFH5 4
Regulation of glucokinase by glucokinase regulatory protein 0.3417623759152267 0.5759537554809065 0.5646464396422561 1.0 0.8804050583021084 27 Q7Z3B4,O15504,Q9BTX1,Q8NFH5 4
Retrograde transport at the trans golgi network 0.3781934865261103 0.5548818389382937 0.5789754847363444 1.0 0.880951532098954 15 O60499 1
Neutrophil degranulation 0.2630849705080907 0.5490647374049251 0.5829610236192366 1.0 0.880951532098954 171 Q969Q5,P14174,O95298,P27105,Q5T9A4,Q07065,Q8NF37,Q99536,Q9H7Z7,Q08722,Q4KMQ2,Q9BTY2,Q9NQX7,Q96CS3,P13473,P30519,P17900,P11279,P15586,Q8WVQ1,O43681,Q9NZJ7,O00487,P04439,Q93050,P61026,O14975,Q9H0U3,P10619,P15291,Q13636,P42785,P07602,P08236,Q13510,O00264,P53634,O15260,P09960 39
Export of viral ribonucleoproteins from nucleus 0.3319967203586939 0.5483642528602831 0.5834418167695543 1.0 0.880951532098954 29 Q7Z3B4,O15504,Q9BTX1,Q8NFH5 4
Sars cov infections 0.2982082981105378 0.5434041353562556 0.5868515790684925 1.0 0.880951532098954 64 P23458,P49356,Q99720,Q9H0U3,Q16706,P27824,Q10469,P46977,P05023,P21964,Q11206,P04843,Q10472,P49354,P49841 15
Tp53 regulates transcription of caspase activators and caspases 0.5750938673341568 0.5317561569423807 0.5948948920397181 1.0 0.880951532098954 2 P04637 1
Sumoylation of ubiquitinylation proteins 0.3330782548181334 0.5289249121557243 0.5968575395550451 1.0 0.880951532098954 28 Q7Z3B4,O15504,Q9BTX1,Q8NFH5 4
Synthesis of ip3 and ip4 in the cytosol 0.5741551939924808 0.5281983977078626 0.5973616413842451 1.0 0.880951532098954 2 Q01968 1
Negative regulation of nmda receptor mediated neuronal transmission 0.4922684501537491 0.5280101312392393 0.597492304181102 1.0 0.880951532098954 6 P07196 1
Postmitotic nuclear pore complex npc reformation 0.3457862716328336 0.5250108878513797 0.5995756220891768 1.0 0.8820741856458219 23 Q7Z3B4,Q9BTX1,Q8NFH5 3
Phase ii conjugation of compounds 0.3354546874923755 0.5229856226845687 0.6009842583932741 1.0 0.8820741856458219 27 Q9NX62,Q99735,P21964 3
Prevention of phagosomal lysosomal fusion 0.5397620538509749 0.5108513856418853 0.6094551243914998 1.0 0.8869195997708383 4 P20339,O14964,P51149 3
G alpha q signalling events 0.3974853233188112 0.5047591187752086 0.6137280325061818 1.0 0.8869195997708383 12 Q8N2K0,Q8NCG7,P63218 3
Inla mediated entry of listeria monocytogenes into host cells 0.56602002503128 0.4977096764205356 0.6186886868260171 1.0 0.8869304788970778 2 P35222 1
Disorders of transmembrane transporters 0.2896194080634393 0.4916689927293418 0.6229533616264011 1.0 0.887390706969853 75 Q12769,Q8NFH5,O14678,Q9GZP9,Q9UBV2,P49721,P35613,P28074,Q9BTX1,O00487,Q7Z3B4,O15504 12
Insulin receptor recycling 0.4160497592996532 0.4888506001878923 0.624947471482967 1.0 0.8874222982360411 9 Q93050,Q9Y487 2
Galactose catabolism 0.5566332916145066 0.4633381025644941 0.6431220383833101 1.0 0.8995975607045098 2 Q96G03 1
Transcription of e2f targets under negative control by p107 rbl1 and p130 rbl2 in complex with hdac1 0.600101539564154 0.4457258515771379 0.6557952883797715 1.0 0.910559482548082 3 P28749 1
G protein beta gamma signalling 0.4426800655189145 0.4442953228581477 0.6568290823251566 1.0 0.910559482548082 7 P31751,P63218 2
Activation of ppargc1a pgc 1alpha by phosphorylation 0.5500625782227666 0.4398253265439067 0.6600636228852081 1.0 0.912325561928466 2 Q16539 1
Sumoylation of transcription factors 0.597783817861111 0.4380819339734604 0.6613268900695937 1.0 0.9131674960802696 3 O75928 1
Tp53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain 0.4965389867784422 0.4292259224388474 0.6677588199309141 1.0 0.9178972626186734 5 Q92600 1
Pi metabolism 0.3489821675678936 0.4271027083976363 0.6693045203468384 1.0 0.9178972626186734 16 P48739,Q9NTJ5,Q10713,Q8NCE2,Q9BTU6 5
Methylation 0.4370768642359626 0.4190032023832304 0.6752137919496146 1.0 0.924116130942806 7 P21964,P78417 2
Transport of the slbp dependant mature mrna 0.3129495087583251 0.4116176433137786 0.6806196976783341 1.0 0.9249540820894244 30 Q7Z3B4,O15504,Q9BTX1,Q8NFH5 4
P75ntr negatively regulates cell cycle via sc1 0.5397371714643182 0.4038465260483777 0.6863255808002564 1.0 0.9249540820894244 2 Q13547 1
Ovarian tumor domain proteases 0.402674611678512 0.3925093782816093 0.694681883322017 1.0 0.9249540820894244 8 Q13546,P06493,Q7Z434 3
Ub specific processing proteases 0.2826101223951178 0.3865089683758985 0.6991197618853844 1.0 0.92645068055159 73 Q92530,O14964,Q70CQ2,Q12834,Q969V5,P28072,P49721,P51784,Q9Y277,P45880,P28074,P21796,Q15388,Q9NZL9,O00487,P43686,Q9UPU5,Q13546 18
Free fatty acids regulate insulin secretion 0.5341051314142555 0.3847474148245602 0.7004245623201553 1.0 0.9268177146909352 2 O95573 1
Plasma lipoprotein assembly remodeling and clearance 0.3304471480178017 0.3582848200047083 0.7201301769920672 1.0 0.9430597815018064 18 Q9BU23,O15118,Q6PIU2,Q8WTV0 4
Recycling of eif2 gdp 0.4510274858176192 0.3564691009780246 0.7214892881541659 1.0 0.9430702680367188 6 P49770,Q13144 2
Nuclear import of rev protein 0.3026738884716593 0.3511695846702495 0.7254611267651405 1.0 0.9464894700599404 31 Q7Z3B4,O15504,Q9BTX1,Q8NFH5 4
Beta oxidation of hexanoyl coa to butanoyl coa 0.4729066987591177 0.3408918170138734 0.733185025333315 1.0 0.9516849224766092 5 P40939 1
Assembly and cell surface presentation of nmda receptors 0.3843773441965582 0.3297091345590174 0.7416197509844731 1.0 0.9571730867631608 9 Q9BUF5,Q13885,P07196 3
Sulfur amino acid metabolism 0.3728583871671604 0.3280173255874278 0.7428985628065248 1.0 0.9571730867631608 11 Q9Y6N5,Q9UBX3,Q13126 3
Constitutive signaling by ligand responsive egfr cancer variants 0.4678985280300738 0.3229094336822506 0.7467638316795748 1.0 0.9572840303256992 5 P07900,P19174,P22681,Q16543 4
Constitutive signaling by egfrviii 0.4678985280300738 0.3229094336822506 0.7467638316795748 1.0 0.9572840303256992 5 P07900,P19174,P22681,Q16543 4
Signaling by egfr in cancer 0.4678985280300738 0.3229094336822506 0.7467638316795748 1.0 0.9572840303256992 5 P07900,P19174,P22681,Q16543 4
Signaling by hippo 0.4420426065163018 0.3212720636984839 0.748004225105404 1.0 0.9579944020616 6 Q4VCS5,P31946,Q9UDY2,Q07157,Q13043 5
Beta oxidation of lauroyl coa to decanoyl coa coa 0.4831553847235924 0.3104633147996857 0.7562086526746621 1.0 0.9640797069715328 4 P40939 1
Glutamate neurotransmitter release cycle 0.5514372167401967 0.2955784603108041 0.7675520251784627 1.0 0.9732085623516202 3 Q96QD8 1
Rhoh gtpase cycle 0.3140688607138792 0.2731608009812249 0.7847296107401274 1.0 0.9847154832909376 22 Q9BXS4,P27105,Q9Y6M7,O75323,Q8TAA9 5
Ca2 pathway 0.4030538626912879 0.2726586966694138 0.7851155873080233 1.0 0.9847154832909376 7 Q08209,P63218 2
Interleukin 35 signalling 0.4706205669968122 0.2705478424998769 0.7867388156868371 1.0 0.9847154832909376 4 P23458 1
Interleukin 27 signaling 0.4706205669968122 0.2705478424998769 0.7867388156868371 1.0 0.9847154832909376 4 P23458 1
Plasma lipoprotein clearance 0.34738548274194 0.2667537020840681 0.7896588032377938 1.0 0.9847154832909376 13 O15118,Q6PIU2,Q8WTV0 3
Sealing of the nuclear envelope ne by escrt iii 0.3755485893417042 0.2657947602108739 0.7903972788587246 1.0 0.9847154832909376 8 Q13885,Q8WUX9,O43633,P04350,Q8NC56,Q9BUF5,P53990 7
Signaling by erbb2 in cancer 0.4677520350657531 0.2616806737874743 0.7935676415583972 1.0 0.9847154832909376 4 P07900,P19174,Q16543 3
Signaling by erbb2 ecd mutants 0.4677520350657531 0.2616806737874743 0.7935676415583972 1.0 0.9847154832909376 4 P07900,P19174,Q16543 3
Fceri mediated ca 2 mobilization 0.4677520350657403 0.2616806737874351 0.7935676415584274 1.0 0.9847154832909376 4 Q08209,P19174,O43865 3
Nuclear pore complex npc disassembly 0.2902591130041755 0.2434506008123365 0.807656348841084 1.0 0.996014366592008 31 Q7Z3B4,O15504,Q9BTX1,Q8NFH5 4
Rhoj gtpase cycle 0.3006587242688078 0.2404408896666116 0.8099884823775358 1.0 0.9971054693627108 27 Q14155,Q658P3,Q9Y6M7,O75323,Q8TAA9,P42167,P17302 7
Abc family proteins mediated transport 0.2720893350948901 0.238238049615026 0.8116964672291553 1.0 0.9971054693627108 54 P40855,P08183,Q9GZP9,Q9UBV2,P49721,O75027,P56589,P28074,O00487,P43686 10
Arms mediated activation 0.4856070087609428 0.2377135578938406 0.8121032673814166 1.0 0.9971054693627108 2 Q9ULH0 1
Displacement of dna glycosylase by apex1 0.4759073842302733 0.2124495146653034 0.8317563601724447 1.0 1.0 2 P29372 1
Ephrin signaling 0.4350140933291734 0.2123631564821536 0.8318237270851987 1.0 1.0 5 Q14155,Q13153,Q16512,Q13177 4
Dap12 interactions 0.4350140933291625 0.2123631564821194 0.8318237270852253 1.0 1.0 5 P01889,P19174,P10321,P62993 4
Rhof gtpase cycle 0.3083372675748863 0.2115982637236166 0.8324204640088828 1.0 1.0 18 Q8TAA9,P42167,Q9Y6M7 3
Activation of smo 0.469023779724641 0.1954247517326877 0.8450604410763025 1.0 1.0 2 Q9Y496 1
Rho gtpase cycle 0.2500677152083597 0.1952687161539637 0.8451825865232991 1.0 1.0 157 P50402,Q9BXS4,Q15904,Q07065,Q9Y512,Q8TAA9,O95202,P08670,Q14739,P41440,Q96CS3,P51572,P30519,O43396,P51648,Q5T8D3,Q86Y07,Q14155,Q658P3,Q86XL3,Q96DH6,Q13505,O15173,Q9Y6M7,A4D1P6,P42167,P49257,O15498 28
Signaling by ntrk3 trkc 0.4674593241551791 0.1916617843683442 0.8480071426080518 1.0 1.0 2 P19174 1
Signaling by fgfr4 in disease 0.4674593241551791 0.1916617843683442 0.8480071426080518 1.0 1.0 2 P19174 1
Nef mediated downregulation of mhc class i complex cell surface expression 0.4427050720100266 0.188823125500134 0.8502314463441769 1.0 1.0 4 Q10567,Q9BXS5,P04439 3
G alpha 12 13 signalling events 0.3815917732589603 0.1882648574977115 0.8506690323864983 1.0 1.0 7 P63218 1
Neuronal system 0.2652028880149185 0.1782537197579408 0.8585237229346325 1.0 1.0 50 P41440,Q14155,O95197,P51812,Q96RD7,P21964,P63218,Q96QD8 8
Dscam interactions 0.4348778960551023 0.1678378235566311 0.8667108656552569 1.0 1.0 4 Q16512,Q13153,Q16539 3
Rnd3 gtpase cycle 0.3067413690340088 0.1627746199923612 0.87069589204039 1.0 1.0 16 O43396,Q07065 2
Cobalamin cbl vitamin b12 transport and metabolism 0.4152754140116542 0.1531394201505215 0.8782883297101742 1.0 1.0 5 O14678 1
Diseases of carbohydrate metabolism 0.3429759272169772 0.1422840318254494 0.8868556589554917 1.0 1.0 9 P08236,P15586,P10253 3
Cytosolic iron sulfur cluster assembly 0.367596364775937 0.1372853078750214 0.8908052830938902 1.0 1.0 7 Q96T76,O75027,P18074,Q9Y5Y2,P28340,P53384 6
Cdc42 gtpase cycle 0.2700887932135622 0.1352664202750582 0.8924012337666429 1.0 1.0 34 Q14155,Q658P3,Q8TAA9,A4D1P6,P42167,Q14739 6
Nade modulates death signalling 0.4414893617021116 0.135056064929856 0.8925675469380083 1.0 1.0 2 P42575 1
Ns1 mediated effects on host pathways 0.2722736696456702 0.1321564407428186 0.8948605540965977 1.0 1.0 33 Q7Z3B4,O15504,Q9BTX1,Q8NFH5 4
Interactions of rev with host cellular proteins 0.2695246761534527 0.13039067540475 0.8962573435588352 1.0 1.0 34 Q7Z3B4,O15504,Q9BTX1,Q8NFH5 4
Rac1 gtpase cycle 0.2644198732321585 0.1299846251083264 0.8965785908690198 1.0 1.0 42 Q14155,P50402,Q8TAA9,P42167,Q86Y07,Q14739 6
Synthesis of pips at the early endosome membrane 0.4820031298904632 0.1274549595103139 0.898580319478449 1.0 1.0 3 Q9BTU6,O00443 2
The phototransduction cascade 0.4181012936939436 0.1259171652384994 0.8997974949288059 1.0 1.0 4 P49356 1
Regulation of lipid metabolism by pparalpha 0.2932956353562858 0.1205553905315314 0.9040432042433332 1.0 1.0 20 Q86X55,P50416,Q15067,P23786,P04035,P37268,P33121 7
Diseases of immune system 0.4333541927409158 0.1196188271291938 0.9047851049201336 1.0 1.0 2 P09429 1
Irak1 recruits ikk complex 0.4333541927409111 0.1196188271291854 0.9047851049201404 1.0 1.0 2 P61088 1
Viral messenger rna synthesis 0.264865287838658 0.1131393564718707 0.9099200733409732 1.0 1.0 35 Q7Z3B4,O15504,Q9BTX1,Q8NFH5 4
Glycogen storage diseases 0.4745193616234338 0.1130784261533091 0.9099683787107083 1.0 1.0 3 P10253 1
Rhobtb1 gtpase cycle 0.2974758844515326 0.109918519923447 0.9124739947666208 1.0 1.0 16 O43396 1
Apc c cdc20 mediated degradation of cyclin b 0.330687018352677 0.1064743595994337 0.9152059978252448 1.0 1.0 10 Q96DE5,Q9UJX5,Q12834,P06493,Q9UJX2,P30260 6
Zbp1 dai mediated induction of type i ifns 0.4088916718847787 0.104740495212189 0.9165817281376094 1.0 1.0 4 Q08211,O15111,Q13546 3
Rip mediated nfkb activation via zbp1 0.4088916718847787 0.104740495212189 0.9165817281376094 1.0 1.0 4 Q08211,O15111,Q13546 3
Traf6 mediated nf kb activation 0.3964923269652531 0.1024186584318523 0.9184243742606432 1.0 1.0 5 Q14258,P09429,O15111,Q7Z434 4
Collagen biosynthesis and modifying enzymes 0.3255671233930944 0.1010616719558029 0.9195015035702044 1.0 1.0 11 O15460,Q32P28 2
Constitutive signaling by overexpressed erbb2 0.4676056338028266 0.1004747984899507 0.9199673894683588 1.0 1.0 3 P07900,Q16543 2
Antigen activates b cell receptor bcr leading to generation of second messengers 0.4676056338028266 0.1004747984899507 0.9199673894683588 1.0 1.0 3 Q13586,O43865 2
Ikk complex recruitment mediated by rip1 0.4023168440826471 0.0904387305317687 0.9279385802673416 1.0 1.0 4 P61088,O15111,Q13546 3
Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects 0.4013171289117513 0.0883242541372735 0.9296189622718432 1.0 1.0 4 P11802 1
Interferon alpha beta signaling 0.3262233375156923 0.0881342575724278 0.9297699687046544 1.0 1.0 10 P55265,P10321,Q9Y3Z3,P61221,P18031,P01889,P04439,P42224,P23458 9
Acyl chain remodeling of cl 0.4601825279763973 0.0876682114391304 0.9301403859100624 1.0 1.0 3 P40939 1
Pyruvate metabolism 0.3043677592448212 0.0775972603562965 0.9381484217307748 1.0 1.0 14 Q15118,P21796,P35613 3
Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps 0.2981817919309762 0.0774648043107309 0.9382537892029092 1.0 1.0 15 Q02818,Q9BTY2,Q07065 3
Notch4 activation and transmission of signal to the nucleus 0.3911138923654447 0.0566671232937283 0.954810363725739 1.0 1.0 2 Q92542 1
Met activates rap1 and rac1 0.3838447088290477 0.0539529414010718 0.9569726569162644 1.0 1.0 4 P63000,Q96N67,P62993 3
Pyroptosis 0.3751957406827488 0.052063890873903 0.9584777848332446 1.0 1.0 5 P09429,P04637,Q8WUX9,O43633 4
Ticam1 rip1 mediated ikk complex recruitment 0.4334898278560354 0.0477661092205449 0.9619026466350028 1.0 1.0 3 P61088,Q13546 2
Chl1 interactions 0.3826658322903554 0.0473496078362101 0.9622345910567488 1.0 1.0 2 P05556 1
Glucuronidation 0.4319248826291166 0.0457199632205846 0.9635334520970869 1.0 1.0 3 Q9NUJ1,Q16851 2
Signaling by insulin receptor 0.2975172239229271 0.0448816368134887 0.9642016537935733 1.0 1.0 14 P31751,Q93050,Q9Y487 3
Trna modification in the nucleus and cytosol 0.3000881988566725 0.0327339845000312 0.9738867226930346 1.0 1.0 13 Q5VV42,O75648 2
Alpha linolenic omega3 and linoleic omega6 acid metabolism 0.3507108159280039 0.029615119565371 0.9763740069333636 1.0 1.0 6 Q15067,O95864 2
Tetrahydrobiopterin bh4 synthesis recycling salvage and regulation 0.4162754303599464 0.026979415557678 0.9784761520602524 1.0 1.0 3 P07900,P00374 2
Interaction between l1 and ankyrins 0.3663118346900412 0.0243811350542272 0.9805485958990928 1.0 1.0 4 O15020,Q01082,Q12955 3
Generation of second messenger molecules 0.3614155966176181 0.0236935386596167 0.9810970599632218 1.0 1.0 5 P19174,Q16512,Q13153,Q13177 4
Signaling by type 1 insulin like growth factor 1 receptor igf1r 0.3580357946700679 0.017246620247593 0.9862398701308552 1.0 1.0 5 P31751 1
Met activates ras signaling 0.4000000000000098 0.010670597581809 0.9914862565000584 1.0 1.0 3 Q96P70,P62993 2
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