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interpro_active_site/advanced/idx2term.json

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+{}

interpro_active_site/basic/idx2term.json

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+{}

interpro_active_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:e1b4c0ae4996a701816440cb819a9eddd1f99c8f27192aa307d6729be74bd991
+size 81693

interpro_active_site/df_merge.tsv

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+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_active_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3198,
+    "annotations_size": 54,
+    "title": "Average number of proteins per term",
+    "value": 2.611111111111111
+}

interpro_active_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C092/C092_val_log2fc"}

interpro_active_site/result.tsv

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+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Histidine acid phosphatase active site [IPR033379]	0.8654568210262927	1.798302158291748	0.0721291379142177	0.982447984777595	0.1256981152405043	2	Q9NPH0	1
+Serine carboxypeptidase, serine active site [IPR018202]	0.7021279122808483	0.816211596756118	0.4143791252902673	0.9999999999997172	0.5434175764342777	3	P10619	1
+Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]	0.5164319248826356	0.2032423363083622	0.838945623721755	1.0	0.9060612736194954	3	Q16881,P00390	2
+Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]	0.4152065081351518	0.0891023334455699	0.9290005829517364	1.0	0.9836476760665446	2	Q9NQ88	1
+Protein-tyrosine phosphatase, active site [IPR016130]	0.3547961659351911	0.0112560739460162	0.9910191420282064	1.0	1.0	5	Q8NCE2,Q8WUK0	2

interpro_active_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["ATP synthase, F0 complex, subunit A, active site [IPR023011]", "ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenosine/AMP deaminase active site [IPR006650]", "Adenylosuccinate synthase,  active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycoside hydrolase, family 2, active site [IPR023232]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Lipase, GDXG, putative serine active site [IPR033140]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Peptidase family C14A, His active site [IPR016129]", "Peptidase family C14A, cysteine active site [IPR033139]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]"], "available_proteins": ["ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADA", "ADSS", "AKT2", "APEH", "ATP5A1", "ATP5B", "ATP6", "ATP6V1A", "ATP6V1B2", "AURKA", "BLMH", "CAMK1", "CAMK2D", "CAMK2G", "CAPN1", "CAPN2", "CASP2", "CDK1", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CHEK2", "CHUK", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CTSA", "CTSC", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "EPHA7", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLUD1", "GSK3A", "GSK3B", "GSR", "GUSB", "HADHB", "HMGCL", "HMGCS1", "JAK1", "LDHA", "LDHB", "LONP1", "MAP2K1", "MAP2K2", "MAP3K7", "MAPK1", "MDH1", "MDH2", "MTMR14", "NCEH1", "NEK9", "NME1", "NME2", "PAK1", "PAK2", "PBK", "PGAM1", "PIK3R4", "PKM", "PKMYT1", "PKN1", "PKN2", "PLK1", "PREP", "PRKACA", "PRKCA", "PRKCD", "PRPF4B", "PTK7", "PTPMT1", "PTPN1", "PTPN11", "RIPK1", "RPS6KA1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SRPK2", "SUCLG1", "TALDO1", "TIGAR", "TOP1", "TPI1", "TPP2", "TRIO", "TTK", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UMPS", "VRK1", "VRK2"], "leading_proteins": ["ACP6", "CTSA", "GSR", "MTMR14", "PTPMT1", "TIGAR", "TXNRD1"]}

interpro_binding_site/advanced/idx2term.json

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+{}

interpro_binding_site/basic/idx2term.json

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+{"0": "EF-Hand 1, calcium-binding site [IPR018247]"}

interpro_binding_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:f4c9976d7d64579890f4cc24a194252f307a81090750fafdf6073887aac06eff
+size 74667

interpro_binding_site/df_merge.tsv

@@ -0,0 +1 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_binding_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3198,
+    "annotations_size": 31,
+    "title": "Average number of proteins per term",
+    "value": 4.483870967741935
+}

interpro_binding_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C092/C092_val_log2fc"}

interpro_binding_site/result.tsv

@@ -0,0 +1,3 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+EF-Hand 1, calcium-binding site [IPR018247]	0.4111704811005147	1.5511227082992085	0.1208722801883184	0.9815663560455926	0.220414157990463	36	Q9NWM8,Q6NUK1,Q9BPX6,Q9Y680,O75340,O95202,Q14257,Q9BRK5,Q02818,P80303	10
+Beta tubulin, autoregulation binding site [IPR013838]	0.5912913348262101	0.7138479744784358	0.4753211905986509	0.9999999979265228	0.526248461019935	4	Q9BUF5,Q13885	2

interpro_binding_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "APOBEC/CMP deaminase, zinc-binding [IPR016192]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]", "Ureohydrolase, manganese-binding site [IPR020855]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "AKT2", "APEX1", "ARG2", "AURKA", "BPNT1", "CALM3", "CALU", "CAMK1", "CAMK2D", "CAMK2G", "CAPN1", "CAPN2", "CDK1", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CETN2", "CHUK", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CYB5B", "DBT", "DCTD", "DLAT", "DLST", "DST", "EHD1", "EHD4", "EIF2AK2", "EPHA7", "EPS15L1", "FKBP10", "FKBP14", "FKBP7", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3A", "GSK3B", "HK1", "HK2", "HMBS", "IDE", "ILKAP", "IQGAP1", "IQGAP2", "JAK1", "LETM1", "MACF1", "MAP2K1", "MAP2K2", "MAP3K7", "MAPK1", "MAPK14", "MCCC1", "MICU1", "MYH10", "MYH14", "MYH9", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "NFS1", "NRDC", "NUCB1", "NUCB2", "OXSR1", "PA2G4", "PAK1", "PAK2", "PAK4", "PC", "PCCA", "PDCD6", "PEF1", "PGD", "PKMYT1", "PKN1", "PKN2", "PLCG1", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1G", "PRKACA", "PRKCA", "PRKCD", "PRKCSH", "PSAT1", "RAB18", "RCN1", "RCN2", "RHOT1", "RHOT2", "RPS6KA1", "RPS6KA3", "S100A11", "SDF4", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "SRPK2", "STK4", "TKT", "TTK", "TUBB", "TUBB2A", "TUBB4A", "TUBB6", "UBE3C", "UQCRC2", "VRK1"], "leading_proteins": ["FKBP14", "FKBP7", "LETM1", "MICU1", "NUCB1", "NUCB2", "PDCD6", "RCN2", "SDF4", "SLC25A24", "TUBB2A", "TUBB6"]}

interpro_conserved_site/advanced/idx2term.json

@@ -0,0 +1 @@
+{}

interpro_conserved_site/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "ABC transporter-like, conserved site [IPR017871]", "1": "AMP-binding, conserved site [IPR020845]"}

interpro_conserved_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:2ce9984020147cbb7ddec548a8ed50e9f9732221a622addea2f62115bff27040
+size 109902

interpro_conserved_site/df_merge.tsv

@@ -0,0 +1 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_conserved_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3198,
+    "annotations_size": 279,
+    "title": "Average number of proteins per term",
+    "value": 2.6594982078853047
+}

interpro_conserved_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C092/C092_val_log2fc"}

interpro_conserved_site/result.tsv

@@ -0,0 +1,33 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Haem oxygenase conserved site [IPR018207]	0.9868585732165204	2.3299541624760285	0.0198085738970283	0.9962352085987592	0.071773923600921	2	P09601	1
+3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]	0.901752190237797	1.9593842378504256	0.0500678051833225	0.999999402638367	0.1429190599102789	2	P40939	1
+Thioredoxin, conserved site [IPR017937]	0.6260618867594204	1.7679437746794076	0.0770703036957913	0.9999999998085546	0.1886194274660157	11	O43396,Q96JJ7,Q9H1E5	3
+Tetraspanin, conserved site [IPR018503]	0.9339593114240904	1.7451920629805462	0.080951442366105	0.9999999999409216	0.1930380548730197	3	O60637,O43657	2
+Sterol reductase, conserved site [IPR018083]	0.8488735919900019	1.7242107342093052	0.0846698070266769	0.9999999999809364	0.1990086123293718	2	Q14739	1
+Lysosome-associated membrane glycoprotein, conserved site [IPR018134]	0.8272841051314183	1.627373686404271	0.1036577566253602	0.999999999999945	0.224190031771128	2	P11279	1
+Syntaxin/epimorphin, conserved site [IPR006012]	0.7716880676479556	1.621733464735276	0.1048604301645079	0.9999999999999624	0.2250466155069055	5	O15400,O60499,Q9P2W9,Q13190	4
+Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]	0.7643205452868777	1.446321914065528	0.1480869320548645	1.0	0.2829261053358688	4	Q8N4Q0,Q8WWV3	2
+Sugar transporter, conserved site [IPR005829]	0.7559449311639767	1.3058110486959826	0.1916168218134646	1.0	0.3383613499111179	2	Q7L0J3	1
+ABC transporter-like, conserved site [IPR017871]	0.5190226360725917	1.229818046417264	0.2187652487864313	1.0	0.3744509473092904	12	P28288,P08183,Q03519,O75027,O14678,P33527	6
+DnaJ domain, conserved site [IPR018253]	0.5305285877721868	1.2250049446911495	0.2205733574693118	1.0	0.3747407028634824	11	Q9NVH1,Q96KC8	2
+Short-chain dehydrogenase/reductase, conserved site [IPR020904]	0.5281433782000715	1.2111760352327694	0.2258279453144107	1.0	0.3772814176210814	11	Q06136,Q8NBN7,Q53GQ0	3
+Glycoside hydrolase, family 29, conserved site [IPR018526]	0.7321652065081508	1.1988166838089325	0.230599233784277	1.0	0.3829594418203172	2	Q9BTY2	1
+C-type lectin, conserved site [IPR018378]	0.7090112640801253	1.0952175225383345	0.2734213508036138	1.0	0.4435148655477224	2	Q9UBG0	1
+Proteasome beta-type subunit, conserved site [IPR016050]	0.5311443079509837	1.062745223901321	0.2878975061132243	1.0	0.4490731458314274	8	P28074,P49721	2
+Tubulin, conserved site [IPR017975]	0.5912913348262101	0.7138479744784358	0.4753211905986509	1.0	0.5821960870007429	4	Q9BUF5,Q13885	2
+HMG box A DNA-binding domain, conserved site [IPR017967]	0.6625733632668338	0.6660592046251714	0.5053732587421185	1.0	0.6051465201246826	3	P26583	1
+Dynamin, GTPase region, conserved site [IPR019762]	0.59918648310387	0.625644255328001	0.531548304340425	1.0	0.6257467380210067	2	O00429	1
+AMP-binding, conserved site [IPR020845]	0.4978070175438696	0.5520686256121131	0.5809013365389009	1.0	0.6724957381508437	6	O14975,O95573,O60488,Q6P1M0,P33121	5
+Intermediate filament protein, conserved site [IPR018039]	0.4648605395951138	0.5469858010500646	0.5843884870842948	1.0	0.6737371400682572	7	P07196,P08670	2
+Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]	0.6229708820781936	0.5233947173665091	0.6006995995873972	1.0	0.6868655257577205	3	Q5T8D3	1
+IMP dehydrogenase / GMP reductase, conserved site [IPR015875]	0.5588235294117533	0.4712776377774592	0.6374424826836103	1.0	0.7200261241648876	2	P12268	1
+Guanylate kinase, conserved site [IPR020590]	0.4807391168180486	0.3695551036986929	0.7117140084117546	1.0	0.7770364198136213	5	Q9NZW5,Q14168,O14936,Q00013	4
+Clathrin adaptor complex, small chain [IPR000804]	0.5758998435054848	0.3682126431552551	0.712714683722725	1.0	0.7770364198136213	3	P61923,P53680	2
+Ribosomal protein S5, N-terminal, conserved site [IPR018192]	0.5015644555694492	0.2824155867625559	0.7776248647281567	1.0	0.8409199118571928	2	P82675	1
+RNA polymerase, beta subunit, conserved site [IPR007121]	0.4921777221526768	0.2556563032917631	0.7982162389353125	1.0	0.8474891612378473	2	P30876	1
+GTP1/OBG, conserved site [IPR006074]	0.4918648310387845	0.2547869795560651	0.7988876322779708	1.0	0.8474891612378473	2	P55039	1
+Actin/actin-like conserved site [IPR020902]	0.5176838810641715	0.2062887466060313	0.8365653684016694	1.0	0.87745014204536	3	P61158,P61160	2
+Ubiquitin interacting motif [IPR003903]	0.4367278834244215	0.1727176562948627	0.8628733646537461	1.0	0.9016541900314424	4	Q8IZ07	1
+Ribosomal protein S2, conserved site [IPR018130]	0.457446808510623	0.16852223691835	0.866172451304627	1.0	0.90172430564922	2	Q9Y399	1
+Oxysterol-binding protein, conserved site [IPR018494]	0.4167111466384482	0.1572486605300229	0.8750488797352547	1.0	0.9075785778666768	5	Q9BZF1,Q9H1P3	2
+Clathrin adaptor, mu subunit, conserved site [IPR018240]	0.4187793427230116	0.0297711324003509	0.9762495815650516	1.0	0.99558078947796	3	Q9BXS5,Q96CW1	2

interpro_conserved_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Aldose 1-epimerase, conserved site [IPR018052]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Anion exchange, conserved site [IPR018241]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Band 7/stomatin-like, conserved site [IPR018080]", "Bax inhibitor 1, conserved site [IPR006213]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "CBX family C-terminal motif [IPR033773]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Connexin, conserved site [IPR017990]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific,  conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA mismatch repair, conserved site [IPR014762]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family A, conserved site [IPR019760]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Di-trans-poly-cis-decaprenylcistransferase-like, conserved site [IPR018520]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "Dihydroorotate dehydrogenase, conserved site [IPR001295]", "DnaJ domain, conserved site [IPR018253]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Ependymin, conserved site [IPR018224]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "Fibrillarin, conserved site [IPR020813]", "Fork head domain conserved site 2 [IPR030456]", "Fork head domain conserved site1 [IPR018122]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glutathione peroxidase conserved site [IPR029760]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 2, conserved site [IPR023230]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Golgin subfamily A member 2, C-terminal binding motif [IPR043937]", "Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site [IPR023076]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "Molybdenum cofactor biosynthesis, conserved site [IPR008284]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NADH:ubiquinone oxidoreductase, subunit 1, conserved site [IPR018086]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site [IPR023058]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosyl pyrophosphate synthetase, conserved site [IPR000842]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P,  conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S14, conserved site [IPR018271]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "Ribosome-binding factor A, conserved site [IPR020053]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Transcription factor TFIIB, conserved site [IPR023486]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "Tyrosine-protein kinase, receptor class V, conserved site [IPR001426]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Uncharacterised protein family UPF0029, Impact, conserved site [IPR020569]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]", "tRNA-dihydrouridine synthase, conserved site [IPR018517]"], "available_proteins": ["AAAS", "AAMP", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ACY1", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK3", "AK4", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANKRD13A", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1M1", "AP2M1", "AP2S1", "AP3M1", "AP3S1", "APEX1", "ARHGEF7", "ARIH2", "ATAD1", "ATAD2", "ATP5C1", "ATP5O", "BAG6", "BAZ1A", "BAZ1B", "BCS1L", "BOP1", "BPNT1", "BPTF", "BRCA1", "BRD2", "BRD4", "BUD31", "CAD", "CALR", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CBL", "CBR1", "CBX1", "CBX2", "CBX3", "CBX5", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDC40", "CDH2", "CDK5RAP1", "CDKAL1", "CETN2", "CHAF1B", "CHD1", "CHD1L", "CHD4", "CLGN", "CMPK1", "CNDP2", "COLEC12", "COPA", "COPZ1", "CORO1B", "CORO1C", "CPOX", "CRYZ", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CWC27", "CYP51A1", "DCAF13", "DCAF7", "DCPS", "DCXR", "DDT", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX55", "DDX6", "DHCR7", "DHDDS", "DHFR", "DHODH", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIMT1", "DIS3", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB4", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC16", "DNAJC2", "DNAJC9", "DNM1L", "DNM2", "DNMBP", "DNMT1", "DRG1", "DRG2", "DSG2", "DST", "DTYMK", "DUS2", "DYNLL1", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4E", "EIF4E2", "ENO1", "ENO2", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPRS", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FBL", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FOXC1", "FUCA1", "FUCA2", "GAA", "GALK1", "GALM", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GJA1", "GLA", "GLB1", "GLO1", "GMPPA", "GNPDA1", "GNS", "GOLGA2", "GPHN", "GPI", "GPX8", "GRHPR", "GRWD1", "GSPT1", "GTF2B", "GTF3C2", "GUF1", "GUSB", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HGS", "HIBADH", "HINT2", "HLA-A", "HLA-B", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCR", "HMOX1", "HMOX2", "HSD17B10", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "ILVBL", "IMPACT", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "ING5", "IQGAP1", "IQGAP2", "IVD", "KDM2A", "KDM5A", "KDSR", "KIF11", "KIF14", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "LAMP1", "LAMP2", "LARS", "LARS2", "LBR", "LDLR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK14", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME2", "MGST2", "MID1", "MIF", "MKRN2", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPST", "MRC2", "MRPL24", "MRPL3", "MRPS11", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "ND1", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS8", "NDUFV1", "NEFL", "NEFM", "NF1", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NSD1", "NSD2", "NSF", "NUBP1", "NUBP2", "NUBPL", "NUDT1", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL11", "OSBPL2", "OSBPL8", "OSBPL9", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PBRM1", "PCNA", "PDIA3", "PDIA4", "PDIA6", "PEBP1", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHF3", "PHGDH", "PHIP", "PI4KA", "PIK3C2A", "PIN1", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PNP", "PNPLA6", "POLA1", "POLD1", "POLG", "POLR1B", "POLR1C", "POLR2B", "POLR2C", "POLR2E", "PPIB", "PPIC", "PPID", "PPIF", "PPIG", "PPIH", "PPIL1", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PRPS1", "PRPS2", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PUS7", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "QDPR", "RACK1", "RAE1", "RANBP2", "RARS", "RARS2", "RBBP7", "RBFA", "RCL1", "RDH13", "RDX", "RIDA", "RNF2", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS24", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "RSF1", "RTCA", "RTN4IP1", "S100A10", "S100A11", "SART1", "SBDS", "SCAP", "SCD", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB1", "SERPINB6", "SERPINH1", "SLC1A5", "SLC25A42", "SLC27A2", "SLC27A4", "SLC2A4", "SLC4A2", "SLIT2", "SMARCA4", "SMS", "SMU1", "SNRNP40", "SNU13", "SPATA5", "SPATA5L1", "SPTBN1", "SPTBN2", "SRCAP", "SRM", "STAM", "STMN1", "STOM", "STRN", "STRN4", "STX10", "STX12", "STX18", "STX5", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SV2A", "SYNE2", "TAF5", "TAP2", "TBL3", "TCP1", "TFB1M", "THOC6", "TK1", "TLN1", "TMBIM6", "TMX1", "TMX3", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRAF2", "TRIM13", "TRIM25", "TRIM28", "TRIM33", "TRIP13", "TRMT11", "TSFM", "TSPAN10", "TSPAN3", "TSPAN6", "TST", "TTF2", "TUBB", "TUBB2A", "TUBB4A", "TUBB6", "TUFM", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UBA5", "UHRF1", "USP10", "USP11", "USP14", "USP19", "USP24", "USP34", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VARS2", "VAT1", "VCL", "VCP", "VIM", "VPS4B", "WARS", "WARS2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR36", "WDR41", "WDR5", "WDR61", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZMYND8"], "leading_proteins": ["ABCB1", "ABCB7", "ABCC1", "ABCD3", "ABCD4", "ACBD5", "ACSL1", "ACSL3", "ACSL4", "ACTR2", "ACTR3", "ANKRD13A", "AP1M1", "AP2M1", "AP2S1", "CASK", "COPZ1", "DNAJC1", "DNAJC11", "DNM1L", "DRG2", "FUCA2", "HADHA", "HMGB2", "HMOX1", "HSD17B12", "IMPDH2", "KDSR", "LAMP1", "LBR", "MPP1", "MPP2", "MPP6", "MRC2", "MRPS2", "MRPS5", "NEFL", "OSBPL2", "OSBPL8", "POLR2B", "PSMB2", "PSMB5", "RDH13", "RTN4IP1", "SLC27A2", "SLC27A4", "STX10", "STX18", "STX5", "STX7", "SV2A", "TAP2", "TMX3", "TMX4", "TSPAN3", "TSPAN6", "TUBB2A", "TUBB6", "TXNL1", "VIM", "ZADH2"]}

interpro_domain/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "P-type ATPase, haloacid dehalogenase domain [IPR044492]"}

interpro_domain/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "P-type ATPase, haloacid dehalogenase domain [IPR044492]", "1": "ABC transporter type 1, transmembrane domain [IPR011527]", "2": "GOLD domain [IPR009038]", "3": "EF-hand domain [IPR002048]", "4": "Thioredoxin domain [IPR013766]", "5": "ABC transporter-like, ATP-binding domain [IPR003439]", "6": "AMP-dependent synthetase/ligase [IPR000873]", "7": "Guanylate kinase-like domain [IPR008144]", "8": "Guanylate kinase/L-type calcium channel beta subunit [IPR008145]", "9": "AP complex, mu/sigma subunit [IPR022775]", "10": "Importin-beta, N-terminal domain [IPR001494]", "11": "Chaperone DnaJ, C-terminal [IPR002939]"}

interpro_domain/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:6b125dfc981da2248b5d4999cdac0462c1332040bb814501918219fb81e0b2ac
+size 452065

interpro_domain/df_merge.tsv

@@ -0,0 +1,3 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+Phospholipid/glycerol acyltransferase [IPR002123]	4	8	2.2334806828393288	0.0255172627986659	2.4611650485436893	6.109223300970874	0.4541526786138767	0.3733328307275969	1.647577392422315	1.6678607828333205	1.200305691546449	0.3080828121567173	0.0002457872884603	0.0742352733278267	0.1419203898220533	0.0557098434243155	0.0007186517412764
+P-type ATPase, haloacid dehalogenase domain [IPR044492]	5	7	2.182020177268643	0.0291080436149202	2.941747572815534	6.145631067961165	0.9567723497044874	0.2732808833570771	1.8358630293390923	1.459204245106796	1.2102525517005158	0.2943240638910574	0.0498968875883284	1.0	0.1898352204968973	0.097689242801984	0.0196049214971061

interpro_domain/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3198,
+    "annotations_size": 2586,
+    "title": "Average number of proteins per term",
+    "value": 2.1759474091260635
+}

interpro_domain/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C092/C092_val_log2fc"}

interpro_domain/result.tsv

@@ -0,0 +1,194 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Phospholipid/glycerol acyltransferase [IPR002123]	0.7580947304029029	2.2334806828393288	0.0255172627986659	1.0	0.0877202998201998	8	Q8NF37,Q9HCL2,Q92604,O15228	4
+Prenylcysteine lyase [IPR010795]	0.9593241551939964	2.2112595225743736	0.0270178706304995	1.0	0.0921744240771395	2	Q9UHG3	1
+P-type ATPase, haloacid dehalogenase domain [IPR044492]	0.800569000047712	2.182020177268643	0.0291080436149202	1.0	0.0971269687589468	7	Q9HD20,P05023,P20020,P98194,P16615	5
+Reticulon [IPR003388]	0.9376956793988656	2.1672269720317487	0.0302175517246383	1.0	0.0992917265056096	4	O95197,Q9NQC3,O75298	3
+Peptidase S54, rhomboid domain [IPR022764]	0.94180225281602	2.135114550753683	0.0327516543648007	1.0	0.1036034811493765	2	Q6NTF9	1
+Fatty acid hydroxylase [IPR006694]	0.9386733416771036	2.121468578159008	0.033882389486278	1.0	0.105944211344339	2	Q15800	1
+GPAT/DHAPAT, acyltransferase domain [IPR041728]	0.9133291614518264	2.0104121810708206	0.044387582318355	1.0	0.1246322343922542	2	Q9HCL2	1
+Glycerol-3-phosphate acyltransferase-like, C-terminal domain [IPR045520]	0.9133291614518264	2.0104121810708206	0.044387582318355	1.0	0.1246322343922542	2	Q9HCL2	1
+BRICHOS domain [IPR007084]	0.9089486858573214	1.9911256068462777	0.046467079914819	1.0	0.1292084609244322	2	Q9Y287	1
+3-hydroxyacyl-CoA dehydrogenase, C-terminal [IPR006108]	0.901752190237797	1.9593842378504256	0.0500678051833225	1.0	0.1351517162881755	2	P40939	1
+3-hydroxyacyl-CoA dehydrogenase, NAD binding [IPR006176]	0.901752190237797	1.9593842378504256	0.0500678051833225	1.0	0.1351517162881755	2	P40939	1
+ABC transporter type 1, transmembrane domain [IPR011527]	0.7018808777429528	1.9554830167285453	0.0505260859993395	1.0	0.1361046441607207	8	P28288,P08183,Q9NUT2,O75027,Q03519,O14678,P33527	7
+Phospholipase D/Transphosphatidylase [IPR001736]	0.8992490613266584	1.9483276519550976	0.0513757704932613	1.0	0.1372497339830308	2	Q8IV08	1
+Acyl-CoA oxidase, C-terminal [IPR002655]	0.896120150187734	1.9344954298747168	0.0530522434241371	1.0	0.140135956583063	2	Q15067	1
+GOLD domain [IPR009038]	0.7448095952777316	1.9215571063572685	0.05466151023362	1.0	0.1426384111646231	7	P49755,Q9Y3A6,Q9BVK6,Q15363,Q9Y3B3	5
+Lysophosphatidylcholine acyltransferase LPCAT1-like [IPR045252]	0.885481852315404	1.8873726642973936	0.0591102191602428	1.0	0.1504586433871466	2	Q8NF37	1
+LEM domain [IPR003887]	0.7858708058256585	1.8775281939581077	0.0604457368779356	1.0	0.1525001712842356	6	P42167,Q86XL3,P50402	3
+ATPase family AAA domain-containing protein 3, N-terminal [IPR021911]	0.8767209011264081	1.848461443524963	0.0645356171505389	1.0	0.1586398345544616	2	Q9NVI7	1
+Cation-transporting P-type ATPase, N-terminal [IPR004014]	0.819605386783588	1.8298603345236153	0.0672708260396428	1.0	0.1638077784538937	5	P20020,P98194,P05023,P16615	4
+Cation-transporting P-type ATPase, C-terminal [IPR006068]	0.819605386783588	1.8298603345236153	0.0672708260396428	1.0	0.1638077784538937	5	P20020,P98194,P05023,P16615	4
+EF-hand domain [IPR002048]	0.4221498857597118	1.815030121924765	0.0695192805731066	1.0	0.1656504766992601	44	O75071,Q9NWM8,Q6NUK1,Q9BPX6,Q9Y680,Q8NF37,O75340,O95202,Q14257,Q9BRK5,Q02818,P80303	12
+Peptidase M1, membrane alanine aminopeptidase [IPR014782]	0.7600659176924804	1.7612628585559698	0.0781939233052531	1.0	0.1773767418134952	6	Q6P179,P09960,Q9UIQ6,Q9NZ08	4
+Aminopeptidase N-like , N-terminal domain [IPR045357]	0.7600659176924804	1.7612628585559698	0.0781939233052531	1.0	0.1773767418134952	6	Q6P179,P09960,Q9UIQ6,Q9NZ08	4
+Glycosyl transferase, family 1 [IPR001296]	0.8535669586983846	1.7452079245424044	0.080948682324297	1.0	0.1820289499918541	2	Q9BT22	1
+Cytochrome b5-like heme/steroid binding domain [IPR001199]	0.7539178160352003	1.733378447020052	0.0830284258344258	1.0	0.1852558319308241	6	O43169,O15173	2
+TRAM/LAG1/CLN8 homology domain [IPR006634]	0.9258215962441232	1.7126763601971808	0.0867720965139895	1.0	0.1883967662076455	3	Q15629,Q96G23	2
+Endoplasmic reticulum vesicle transporter, N-terminal [IPR039542]	0.9255086071987394	1.7114245628693652	0.087002766035148	1.0	0.1883967662076455	3	Q9Y282,Q96RQ1	2
+Endoplasmic reticulum vesicle transporter, C-terminal [IPR012936]	0.9255086071987394	1.7114245628693652	0.087002766035148	1.0	0.1883967662076455	3	Q9Y282,Q96RQ1	2
+Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain [IPR019564]	0.8388610763454503	1.6793490122873056	0.0930840441287066	1.0	0.1981196198492472	2	Q13505	1
+Metaxin, glutathione S-transferase domain [IPR033468]	0.8388610763454503	1.6793490122873056	0.0930840441287066	1.0	0.1981196198492472	2	Q13505	1
+N-acetylgalactosaminyltransferase [IPR045885]	0.8074883308050977	1.6294326647568875	0.1032214585445117	1.0	0.2125244361433975	4	Q10472	1
+Plasma membrane calcium transporting P-type ATPase, C-terminal [IPR022141]	0.8188360450563188	1.5893846408938066	0.111973580028938	1.0	0.2239471600578761	2	P20020	1
+ERAP1-like C-terminal domain [IPR024571]	0.7968065122103908	1.5842943484940768	0.1131267512954514	1.0	0.2246895382872791	4	Q6P179,Q9UIQ6,Q9NZ08	3
+RBM3/CIRBP, RNA recognition motif [IPR034278]	0.8141426783479333	1.5682603602745997	0.1168203828476823	1.0	0.2292926561722956	2	P98179	1
+Dynamin, N-terminal [IPR045063]	0.6713871143611447	1.5676978314501937	0.1169516680167277	1.0	0.2292926561722956	7	Q8IWA4	1
+Dynamin-type guanine nucleotide-binding (G) domain [IPR030381]	0.6713871143611447	1.5676978314501937	0.1169516680167277	1.0	0.2292926561722956	7	Q8IWA4	1
+SUN coiled coil domain 2 [IPR040994]	0.8125782227784897	1.561216180959641	0.1184727524179656	1.0	0.2320988922370144	2	O94901	1
+Amino acid transporter, transmembrane domain [IPR013057]	0.8078848560701049	1.5400760968961131	0.1235418055059227	1.0	0.240029383199336	2	Q96QD8	1
+CBS domain [IPR000644]	0.6534185054363503	1.47941689346872	0.1390289278188907	1.0	0.2575421256014695	7	Q8NE01,P51798,P51790	3
+Thioredoxin domain [IPR013766]	0.4513419550662744	1.4633931743418933	0.1433598253130403	1.0	0.2627416784263093	26	Q96JJ7,Q9Y320,O43396,Q9H3N1,Q96J42,Q9H1E5	6
+Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337]	0.7891113892365429	1.4554287513225834	0.1455506016124355	1.0	0.2655502447373973	2	O60506	1
+Ricin B, lectin domain [IPR000772]	0.6916032351714702	1.4471746848752436	0.1478480047878421	1.0	0.267367091175776	6	Q9UBG0,Q10472	2
+Alcohol dehydrogenase, N-terminal [IPR013154]	0.7244484295646729	1.4135383330452036	0.1574974986051158	1.0	0.2799233892734224	5	Q8N4Q0,Q8WWV3	2
+Major facilitator superfamily domain [IPR020846]	0.7564182842830145	1.4126281578840028	0.1577650853030574	1.0	0.280014077277767	4	Q14728,Q9H2V7,Q7L0J3	3
+Sterol-sensing domain [IPR000731]	0.8494522691705709	1.4052132365764831	0.1599578792407836	1.0	0.2830619861682568	3	O15118,P04035	2
+Glycosyltransferase 2-like [IPR001173]	0.6825162127283004	1.4049672829075317	0.1600310073271513	1.0	0.2830619861682568	6	Q10472	1
+Tim44-like domain [IPR007379]	0.7778473091364295	1.4046039223639872	0.1601390896226449	1.0	0.2830619861682568	2	O43615	1
+Syntaxin, N-terminal domain [IPR006011]	0.7709637046307851	1.3735439964372629	0.1695832935155026	1.0	0.2930786969437617	2	O15400	1
+CARG-binding factor, N-terminal [IPR012956]	0.760012515644555	1.3241480445956593	0.1854538819651152	1.0	0.3122289965897057	2	Q99729	1
+G-protein gamma-like domain [IPR015898]	0.7534418022528412	1.294530496005043	0.1954822425406301	1.0	0.3223960964349934	2	P63218	1
+Tim10-like [IPR004217]	0.7257357545397575	1.2814841714766183	0.2000236561145705	1.0	0.326347744297968	4	Q9Y5J6,P62072,Q9Y5J9	3
+BSD domain [IPR005607]	0.7493742177722111	1.2762067725213837	0.2018824352034309	1.0	0.3289596764101722	2	P32780	1
+ABC transporter-like, ATP-binding domain [IPR003439]	0.5190226360725917	1.229818046417264	0.2187652487864313	1.0	0.3432738302016317	12	P28288,P08183,Q03519,O75027,O14678,P33527	6
+CNNM, transmembrane domain [IPR002550]	0.7384230287859779	1.2269292687917053	0.2198491766439203	1.0	0.3432738302016317	2	Q8NE01	1
+Ion transporter-like, CBS domain [IPR044751]	0.7384230287859779	1.2269292687917053	0.2198491766439203	1.0	0.3432738302016317	2	Q8NE01	1
+Alpha-L-fucosidase, C-terminal [IPR031919]	0.7321652065081508	1.1988166838089325	0.230599233784277	1.0	0.3562270711164214	2	Q9BTY2	1
+Prolyl 4-hydroxylase alpha-subunit, N-terminal [IPR013547]	0.7268460575719745	1.1749534289237225	0.2400133482199091	1.0	0.3667729867079838	2	O15460	1
+Autophagy-related, C-terminal [IPR015412]	0.7224655819774666	1.1553269012118077	0.2479565837480406	1.0	0.3754190430751949	2	Q96RL7	1
+JAB1/MPN/MOV34 metalloenzyme domain [IPR000555]	0.5880447742074583	1.1542497154002889	0.2483978056086395	1.0	0.375867013050873	7	Q7L5N1,Q92905,O00303,O00487	4
+Stromal interaction molecule, Orai1-activating region [IPR032393]	0.7183979974968657	1.1371252580351587	0.2554859264017501	1.0	0.3825631764186021	2	Q13586	1
+Band 7 domain [IPR001107]	0.5409384224768495	1.1152840968398925	0.264728698123819	1.0	0.3923142769903702	8	O75477,Q99623,P27105,Q14254	4
+Band 3 cytoplasmic domain [IPR013769]	0.7124530663329407	1.1105670460706571	0.2667547539737471	1.0	0.3937373252146747	2	Q9Y6M7	1
+Bicarbonate transporter, C-terminal [IPR011531]	0.7124530663329407	1.1105670460706571	0.2667547539737471	1.0	0.3937373252146747	2	Q9Y6M7	1
+CD209-like, C-type lectin-like domain [IPR033989]	0.7090112640801253	1.0952175225383345	0.2734213508036138	1.0	0.4001514505818593	2	Q9UBG0	1
+C-type lectin-like [IPR001304]	0.7090112640801253	1.0952175225383345	0.2734213508036138	1.0	0.4001514505818593	2	Q9UBG0	1
+RBM1CTR [IPR012604]	0.7080725907384173	1.0910348652676698	0.2752575414170963	1.0	0.4023832685724201	2	Q96E39	1
+v-SNARE, coiled-coil homology domain [IPR042855]	0.7695791366899696	1.0827732487132773	0.278909082254402	1.0	0.4044890938116434	3	O15498	1
+Longin domain [IPR010908]	0.7695791366899696	1.0827732487132773	0.278909082254402	1.0	0.4044890938116434	3	O15498	1
+LRRC8, pannexin-like TM region [IPR021040]	0.706195244055063	1.082674333709742	0.2789530002507039	1.0	0.4044890938116434	2	Q8TDW0	1
+Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain [IPR008333]	0.7033792240300474	1.0701459171778245	0.2845536336180201	1.0	0.4094912056406232	2	Q9UHQ9	1
+Rpn11/EIF3F, C-terminal [IPR024969]	0.6746005089261919	1.06281157231651	0.2878674104958039	1.0	0.4127786510320649	4	O00487,Q7L5N1	2
+Zinc finger, CHHC-type [IPR012996]	0.7524256651017073	1.0141546887275652	0.3105089457711967	1.0	0.4345108948941096	3	P31943,P52597	2
+PB1 domain [IPR000270]	0.6880475594493052	1.0022293469535504	0.3162328370583664	1.0	0.4401389217615369	2	Q92734	1
+Exosome complex component, N-terminal domain [IPR025721]	0.6836670838548118	0.9829278750450118	0.3256429374848568	1.0	0.4496063194531979	2	Q13868	1
+PSI domain [IPR016201]	0.6808510638297804	0.9705470079782528	0.3317739054353723	1.0	0.4536406378521357	2	P05556	1
+Far upstream element-binding protein, C-terminal [IPR015096]	0.6792866082603339	0.9636783652630164	0.3352072042951062	1.0	0.456956157252053	2	Q92945	1
+Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862]	0.7362854722691725	0.9500173952007788	0.3421034138734025	1.0	0.4624565751576679	3	Q32P28	1
+Acyltransferase, C-terminal domain [IPR032098]	0.7248826291079751	0.9050203603923296	0.3654546008747676	1.0	0.4789992893371257	3	Q6UWP7,Q92604	2
+Domain of unknown function DUF3517 [IPR021905]	0.7223615125896055	0.8951122667448913	0.3707270772337538	1.0	0.4839476131885348	3	Q70CQ2	1
+Oxidoreductase FAD/NAD(P)-binding [IPR001433]	0.7154828048363391	0.8681605642288709	0.3853064395701913	1.0	0.4933971431391484	3	P16435	1
+Flavoprotein pyridine nucleotide cytochrome reductase [IPR001709]	0.7154828048363391	0.8681605642288709	0.3853064395701913	1.0	0.4933971431391484	3	P16435	1
+FAD-binding domain, ferredoxin reductase-type [IPR017927]	0.7154828048363391	0.8681605642288709	0.3853064395701913	1.0	0.4933971431391484	3	P16435	1
+Ancestral coatomer element 1, Sec16/Sec31 [IPR024298]	0.6555068836045145	0.8602443191555226	0.3896543790180433	1.0	0.4960748780377845	2	O15027	1
+CS domain [IPR007052]	0.4840963547807055	0.8543608636645027	0.3929050734871699	1.0	0.4960748780377845	9	Q9P035,Q15185,Q9HB71	3
+EF hand associated, type-2 [IPR013567]	0.6536295369211436	0.8521660305139337	0.3941219475998094	1.0	0.4960748780377845	2	Q8IXI2	1
+EF hand associated, type-1 [IPR013566]	0.6536295369211436	0.8521660305139337	0.3941219475998094	1.0	0.4960748780377845	2	Q8IXI2	1
+MIRO domain [IPR020860]	0.6536295369211436	0.8521660305139337	0.3941219475998094	1.0	0.4960748780377845	2	Q8IXI2	1
+FAD/NAD(P)-binding domain [IPR023753]	0.5610431523965902	0.837540940194859	0.4022885744988005	1.0	0.5035422331335422	6	Q9Y6N5	1
+Target SNARE coiled-coil homology domain [IPR000727]	0.5128568621878694	0.7791392320469029	0.4358977019074883	1.0	0.5267436715573667	7	O15400,O60499,Q9UNK0,Q13190	4
+NOPS [IPR012975]	0.6888888888888768	0.7652761001358066	0.444107152572144	1.0	0.5343710182780504	3	Q8WXF1,P23246	2
+EB1, C-terminal [IPR004953]	0.6260951188986289	0.7355212671567575	0.462022092717901	1.0	0.5490758877612556	2	Q15555	1
+Fibronectin type II domain [IPR000562]	0.6786476905821646	0.7263160077653008	0.467645068201648	1.0	0.5549931832810746	3	Q9UBV2	1
+Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]	0.5912913348262101	0.7138479744784358	0.4753211905986509	1.0	0.5615469450036464	4	Q9BUF5,Q13885	2
+Tubulin/FtsZ, GTPase domain [IPR003008]	0.5912913348262101	0.7138479744784358	0.4753211905986509	1.0	0.5615469450036464	4	Q9BUF5,Q13885	2
+AMP-dependent synthetase/ligase [IPR000873]	0.4979630209965758	0.7060326328835148	0.4801678439725332	1.0	0.5654435539676552	7	O14975,O95573,O60488,Q6P1M0,Q9P265,P33121	6
+Transcription factor CBF/NF-Y/archaeal histone domain [IPR003958]	0.6113892365456726	0.6748901764068153	0.4997455422330339	1.0	0.5874281691884663	2	Q9NRG0	1
+Peptidase M28 [IPR007484]	0.660571149387086	0.6586377233248139	0.510128432743977	1.0	0.5988552518585398	3	Q969V3	1
+Choline/carnitine acyltransferase domain [IPR039551]	0.6602016299634423	0.6572702094163263	0.5110071881519049	1.0	0.5995755846464729	3	P23786	1
+NIPSNAP [IPR012577]	0.6556681470432768	0.6405487566424775	0.5218159018908619	1.0	0.6111485155297867	3	O75323	1
+Zinc finger C2H2 AKAP95-type [IPR034736]	0.6550860719874629	0.6384094459081496	0.523207183668684	1.0	0.6122234284919533	3	Q9ULX6,O43823	2
+GTPase effector domain [IPR020850]	0.59918648310387	0.625644255328001	0.531548304340425	1.0	0.6196276303955365	2	O00429	1
+Dynamin GTPase effector [IPR003130]	0.59918648310387	0.625644255328001	0.531548304340425	1.0	0.6196276303955365	2	O00429	1
+Dynamin stalk domain [IPR000375]	0.59918648310387	0.625644255328001	0.531548304340425	1.0	0.6196276303955365	2	O00429	1
+Guanylate kinase-like domain [IPR008144]	0.4810404261986908	0.6240184302086846	0.5326154814313342	1.0	0.6196276303955365	7	O14936,Q00013,Q14168,Q9UDY2,Q07157,Q9NZW5	6
+Guanylate kinase/L-type calcium channel beta subunit [IPR008145]	0.4810404261986908	0.6240184302086846	0.5326154814313342	1.0	0.6196276303955365	7	O14936,Q00013,Q14168,Q9UDY2,Q07157,Q9NZW5	6
+Serine-threonine/tyrosine-protein kinase, catalytic domain [IPR001245]	0.4486269760281844	0.6239662683372104	0.5326497379618242	1.0	0.6196276303955365	8	P23458,Q9H5K3	2
+AMP-binding enzyme, C-terminal domain [IPR025110]	0.5664482642123386	0.614144231172041	0.5391200220656063	1.0	0.6260280094574125	4	O14975	1
+SUN domain [IPR012919]	0.6482587842431484	0.6134516013220029	0.539577775379688	1.0	0.6262783335421334	3	O94901	1
+Intermediate filament head, DNA-binding domain [IPR006821]	0.5625860734669725	0.5989254021587882	0.5492226311664572	1.0	0.6360455549469137	4	P07196,P08670	2
+Class II aldolase/adducin N-terminal [IPR001303]	0.5913642052565611	0.5946448872837522	0.5520808687392531	1.0	0.6388896463387469	2	P35611	1
+Exportin-2, central domain [IPR013713]	0.6416275430359999	0.5894582956002284	0.5555538804614448	1.0	0.6422272395499761	3	P55060,O95373	2
+DnaJ domain [IPR001623]	0.3602096337089302	0.5763860223695468	0.5643542900518601	1.0	0.6521091126336507	19	Q96KC8,Q9NVH1,Q9Y2G8	3
+Tudor domain [IPR002999]	0.5015135441932621	0.5682788547083494	0.5698456347561649	1.0	0.6572795769310626	6	Q16637,Q14739	2
+Intermediate filament, rod domain [IPR039008]	0.4648605395951138	0.5469858010500646	0.5843884870842948	1.0	0.6725539063640349	7	P07196,P08670	2
+Extended synaptotagmin, C-terminal C2 domain [IPR037752]	0.5782227784730805	0.5436729177738162	0.5866665720474475	1.0	0.6739759019612169	2	A0FGR8	1
+Synaptotagmin, SMP domain [IPR039010]	0.5782227784730805	0.5436729177738162	0.5866665720474475	1.0	0.6739759019612169	2	A0FGR8	1
+Extended synaptotagmin, C2A domain [IPR037733]	0.5782227784730805	0.5436729177738162	0.5866665720474475	1.0	0.6739759019612169	2	A0FGR8	1
+Extended synaptotagmin, C2B domain [IPR037749]	0.5782227784730805	0.5436729177738162	0.5866665720474475	1.0	0.6739759019612169	2	A0FGR8	1
+Acyl-CoA-binding protein, ACBP [IPR000582]	0.6229708820781936	0.5233947173665091	0.6006995995873972	1.0	0.6885678920802345	3	Q5T8D3	1
+CTP synthase, N-terminal [IPR017456]	0.5666458072590649	0.5000324852728192	0.6170522037613626	1.0	0.7020224368354085	2	Q9NRF8	1
+CTP synthase GATase domain [IPR033828]	0.5666458072590649	0.5000324852728192	0.6170522037613626	1.0	0.7020224368354085	2	Q9NRF8	1
+NudC N-terminal domain [IPR025934]	0.5628911138923541	0.486153509900704	0.6268583303506845	1.0	0.7109893167924869	2	Q8IVD9	1
+IMP dehydrogenase/GMP reductase [IPR001093]	0.5588235294117533	0.4712776377774592	0.6374424826836103	1.0	0.721727784684683	2	P12268	1
+Glutathione S-transferase, N-terminal [IPR004045]	0.4157414651363635	0.4565682371117183	0.647981413705836	1.0	0.7310994484482075	8	Q8TB36,Q9H7Z7	2
+Peptidase S9, prolyl oligopeptidase, catalytic domain [IPR001375]	0.5238491316410919	0.4516210720429309	0.6515419869635524	1.0	0.7344758405787909	4	Q4J6C6	1
+Oxoglutarate/iron-dependent dioxygenase [IPR005123]	0.4713160678045222	0.4390124886783632	0.660652487204421	1.0	0.7437733269092873	6	Q32P28	1
+Prolyl 4-hydroxylase, alpha subunit [IPR006620]	0.4713160678045222	0.4390124886783632	0.660652487204421	1.0	0.7437733269092873	6	Q32P28	1
+Immunoglobulin C1-set [IPR003597]	0.5972557933451974	0.4363467198886537	0.6625851895109509	1.0	0.7446524554868835	3	P04439	1
+MHC class I alpha chain, alpha1 alpha2 domains [IPR001039]	0.5972557933451974	0.4363467198886537	0.6625851895109509	1.0	0.7446524554868835	3	P04439	1
+MHC class I-like antigen recognition-like [IPR011161]	0.5972557933451974	0.4363467198886537	0.6625851895109509	1.0	0.7446524554868835	3	P04439	1
+MHC class I, alpha chain, C-terminal [IPR010579]	0.5972557933451974	0.4363467198886537	0.6625851895109509	1.0	0.7446524554868835	3	P04439	1
+MoaB/Mog domain [IPR001453]	0.5406758448059955	0.4070665306284998	0.6839591245806642	1.0	0.7617219191066312	2	Q9NQX3	1
+Histone deacetylase domain [IPR023801]	0.5397371714643182	0.4038465260483777	0.6863255808002564	1.0	0.7640283908521149	2	Q13547	1
+Nucleotidyl transferase domain [IPR005835]	0.5391113892365333	0.4017056380500927	0.6879006747114595	1.0	0.765062995012468	2	Q9NR50	1
+BRO1 domain [IPR004328]	0.5369211514392908	0.3942492511833922	0.6933970269186907	1.0	0.7685952825656962	2	Q8WUM4	1
+MRG domain [IPR026541]	0.5366082603253955	0.3931887473560802	0.6941800801406508	1.0	0.7691301145003098	2	Q9UBU8	1
+Nucleoporin, Nup133/Nup155-like, C-terminal [IPR007187]	0.5356695869837175	0.3900143288570299	0.6965259514073896	1.0	0.771068540385064	2	Q8WUM0	1
+Synaptotagmin-like mitochondrial-lipid-binding domain [IPR031468]	0.5784037558685422	0.3759855114957027	0.7069276672512044	1.0	0.7799125202694601	3	A0FGR8,Q8IWB9	2
+Heat shock chaperonin-binding [IPR006636]	0.4781306590564825	0.359938127275241	0.7188934038152435	1.0	0.7894975615969964	5	Q9UMX0	1
+Ribosome biogenesis protein BMS1/TSR1, C-terminal [IPR007034]	0.5234668335419144	0.3497423187129543	0.7265320911985129	1.0	0.7947597241283225	2	Q2NL82	1
+AARP2CN [IPR012948]	0.5234668335419144	0.3497423187129543	0.7265320911985129	1.0	0.7947597241283225	2	Q2NL82	1
+Bms1/Tsr1-type G domain [IPR030387]	0.5234668335419144	0.3497423187129543	0.7265320911985129	1.0	0.7947597241283225	2	Q2NL82	1
+Potentiating neddylation domain [IPR005176]	0.5604880813469122	0.3217296230459757	0.7476575341235452	1.0	0.8133960383859856	3	Q96GG9	1
+Stromalin conservative domain [IPR020839]	0.5125156445556813	0.3152502868084432	0.7525716272368392	1.0	0.8173667484395071	2	Q8WVM7	1
+STAG [IPR013721]	0.5125156445556813	0.3152502868084432	0.7525716272368392	1.0	0.8173667484395071	2	Q8WVM7	1
+Major sperm protein (MSP) domain [IPR000535]	0.5580594679186307	0.3146264965964742	0.753045258764006	1.0	0.8174091953512662	3	Q8NHP6,Q9P0L0	2
+L27 domain, C-terminal [IPR014775]	0.480588603631811	0.3021390354044653	0.7625460761823899	1.0	0.8235622163470335	4	Q9NZW5,Q14168,O14936	3
+L27 domain [IPR004172]	0.480588603631811	0.3021390354044653	0.7625460761823899	1.0	0.8235622163470335	4	Q9NZW5,Q14168,O14936	3
+Zinc finger, UBP-type [IPR001607]	0.5081351689611879	0.3019125132776486	0.7627187564104716	1.0	0.8235622163470335	2	P45974	1
+ZU5 domain [IPR000906]	0.504693366708376	0.2916226280570583	0.770575172419774	1.0	0.8296249738915048	2	Q12955	1
+Ribosomal protein S5, N-terminal [IPR013810]	0.5015644555694492	0.2824155867625559	0.7776248647281567	1.0	0.8344140664676404	2	P82675	1
+Ribosomal protein S5, C-terminal [IPR005324]	0.5015644555694492	0.2824155867625559	0.7776248647281567	1.0	0.8344140664676404	2	P82675	1
+SCP2 sterol-binding domain [IPR003033]	0.544913928012527	0.2772857684576214	0.7815606864200255	1.0	0.8375946684965545	3	P51659,Q6YN16	2
+FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]	0.3678680301240127	0.2749865093003601	0.7833266029318888	1.0	0.8384447827739505	10	Q9Y680	1
+Exportin-1/Importin-beta-like [IPR013598]	0.4708829054477206	0.2713638725208795	0.7861111854312945	1.0	0.8407293323098957	4	O14980,Q9Y5L0,Q9HAV4	3
+RNA polymerase Rpb2, domain 7 [IPR007641]	0.4921777221526768	0.2556563032917631	0.7982162389353125	1.0	0.8512112139739043	2	P30876	1
+DNA-directed RNA polymerase, subunit 2, hybrid-binding domain [IPR007120]	0.4921777221526768	0.2556563032917631	0.7982162389353125	1.0	0.8512112139739043	2	P30876	1
+RNA polymerase Rpb2, domain 2 [IPR007642]	0.4921777221526768	0.2556563032917631	0.7982162389353125	1.0	0.8512112139739043	2	P30876	1
+RNA polymerase Rpb2, domain 3 [IPR007645]	0.4921777221526768	0.2556563032917631	0.7982162389353125	1.0	0.8512112139739043	2	P30876	1
+RNA polymerase, beta subunit, protrusion [IPR007644]	0.4921777221526768	0.2556563032917631	0.7982162389353125	1.0	0.8512112139739043	2	P30876	1
+GTP binding protein, second domain [IPR031662]	0.4918648310387845	0.2547869795560651	0.7988876322779708	1.0	0.8515760169294445	2	P55039	1
+SGS domain [IPR007699]	0.4899874843554301	0.2496021805543604	0.8028950121168446	1.0	0.8549020536027065	2	Q9HB71	1
+Acyl-CoA oxidase/dehydrogenase, central domain [IPR006091]	0.3625722732293469	0.249466892533119	0.8029996474095027	1.0	0.8549020536027065	10	Q15067,O15254	2
+Ribosomal protein S7 domain [IPR023798]	0.4884230287859701	0.2453224814647796	0.8062067458186468	1.0	0.8579632282662637	2	Q9Y2R9	1
+PDZ domain 6 [IPR041489]	0.4871714643304021	0.2419256842182067	0.8088377480486146	1.0	0.8593485687977476	2	Q92614	1
+Vps4 oligomerisation, C-terminal [IPR015415]	0.4868585732165065	0.2410802430114363	0.8094929250353378	1.0	0.8596914596063177	2	P55072	1
+Septin-type guanine nucleotide-binding (G) domain [IPR030379]	0.4434738513028119	0.2394648173235025	0.8107451746259391	1.0	0.8599355029119768	5	Q16181	1
+AP complex, mu/sigma subunit [IPR022775]	0.4191729323308379	0.2361000057368944	0.8133550694783744	1.0	0.8613170391773449	6	P48444,Q96CW1,Q92572,P61923,P53680	5
+Glutamine amidotransferase [IPR017926]	0.4517845961177277	0.2142557248656212	0.8303476427152261	1.0	0.8767761269500344	4	Q9NRF8,P49915,P17812	3
+Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain [IPR004099]	0.5164319248826356	0.2032423363083622	0.838945623721755	1.0	0.8826335976177617	3	Q16881,P00390	2
+Fragile X-related 1 protein, C-terminal region 1 [IPR032172]	0.4621401752190087	0.1791649271005668	0.8578082022034197	1.0	0.8999156230823705	2	P51116	1
+Importin-beta, N-terminal domain [IPR001494]	0.3277864992150831	0.1636194286746511	0.8700307489611498	1.0	0.9119981827375492	13	Q92973,Q14974,O14980,Q96P70,Q9UIA9,O00410,O95373,P55060,O15397,Q8TEX9,O43592,Q9HAV4	12
+VHS domain [IPR002014]	0.4477471839799601	0.14767746336222	0.882597318230214	1.0	0.9206924828331317	2	O14964	1
+Glutamine amidotransferase type 2 domain [IPR017932]	0.4851330203442974	0.1336929814368774	0.8936453553407726	1.0	0.9295924734156228	3	Q06203,Q06210	2
+Mu homology domain [IPR028565]	0.4189104571070695	0.1278408269337856	0.8982749399077719	1.0	0.9332820388113692	4	P48444,Q9BXS5,Q96CW1	3
+Kinesin-like [IPR022164]	0.4321026282853445	0.1173410442837907	0.906589801035088	1.0	0.9407870086182736	2	Q12756	1
+Kinesin-like KIF1-type [IPR022140]	0.4321026282853445	0.1173410442837907	0.906589801035088	1.0	0.9407870086182736	2	Q12756	1
+Metastasis-associated protein MTA1, R1 domain [IPR035170]	0.4744913928012615	0.1130261265306512	0.9100098419566448	1.0	0.943578769566914	3	O94776,Q13330	2
+C2 domain [IPR000008]	0.3159945865690592	0.105516949183123	0.9159656215615716	1.0	0.948993228108263	13	Q96PU5	1
+Arfaptin homology (AH) domain [IPR010504]	0.4214643304130052	0.0990192876326041	0.9211229560463	1.0	0.953572443689244	2	P53365	1
+Ubiquitin system component CUE [IPR003892]	0.3962636305420852	0.0778799033378959	0.937923585662189	1.0	0.969344672375831	4	Q9UKV5	1
+F-BAR domain [IPR031160]	0.4466353677621372	0.0662248441105149	0.9471988174487388	1.0	0.9742215169699724	3	Q15642,Q9UKS6	2
+FCH domain [IPR001060]	0.4466353677621372	0.0662248441105149	0.9471988174487388	1.0	0.9742215169699724	3	Q15642,Q9UKS6	2
+Proteasome activator PA28, N-terminal domain [IPR003185]	0.4460093896713716	0.0652938043378905	0.947940075241846	1.0	0.9742215169699724	3	Q9UL46,P61289	2
+Proteasome activator PA28, C-terminal domain [IPR003186]	0.4460093896713716	0.0652938043378905	0.947940075241846	1.0	0.9742215169699724	3	Q9UL46,P61289	2
+Peptidyl-prolyl cis-trans isomerase, PpiC-type [IPR000297]	0.3967459324155041	0.0634555566915666	0.9494037485040838	1.0	0.975042928368372	2	Q9Y237	1
+Chaperone DnaJ, C-terminal [IPR002939]	0.3637218045112881	0.0624179958596962	0.9502299642783132	1.0	0.9755040443127104	6	Q96EY1,Q9UBS4,Q9UDY4,O60884,P31689	5
+AGC-kinase, C-terminal [IPR000961]	0.323400852470909	0.0560486207180876	0.9553030742761386	1.0	0.979934053977824	8	P31751	1
+Protein kinase, C-terminal [IPR017892]	0.3258839939001091	0.0079360932183735	0.993667980214801	1.0	1.0	7	P31751	1
+Protein-tyrosine phosphatase, catalytic [IPR003595]	0.3254067584480495	0.0075409656702135	0.9939832369432846	1.0	1.0	2	P18031	1
+Tyrosine-specific protein phosphatase, PTPase domain [IPR000242]	0.3254067584480495	0.0075409656702135	0.9939832369432846	1.0	1.0	2	P18031	1
+Heat shock protein DnaJ, cysteine-rich domain [IPR001305]	0.3893583724569718	0.0016453335135337	0.9986872143844918	1.0	1.0	3	O60884,P31689	2
+YTH domain [IPR007275]	0.3022528160200145	0.0001546855124629	0.9998765788183182	1.0	1.0	2	Q7Z739	1

interpro_family/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "Mitochondrial carrier protein [IPR002067]", "1": "P-type ATPase [IPR001757]"}