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0d2e574 verified
Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
C type lectin receptors clrs 0.5585033891765643 4.281913962750278 1.8529262921340717e-05 0.0254270598881588 0.020106695671043 57 P62191,P60900,P43686,P62333,Q13177,P25789,Q15008,P25786,P20618,P25787,Q16512,O00487,O15111,Q13616,Q00653,O14818,O43242,P28066,Q14997,P61081,P55036,P49720,O43318,P61289,P49427,O75832,Q9UNM6,Q08209,P28070,P49721,P48556,Q8TBC4,Q14790,P28072,P25788,O00231,Q04206,Q13153,P28074,P17612,P62195,Q13200 42
Fc epsilon receptor fceri signaling 0.5481567237454193 4.160944739902802 3.169337745045908e-05 0.0430981881853961 0.020106695671043 58 P62993,P62191,P60900,P43686,P62333,Q13177,P25789,Q15008,P25786,P20618,P25787,Q16512,O00487,O15111,Q13616,O14818,P19174,O43242,P28066,Q14997,P49427,P55036,P49720,O43318,P61289,O75832,Q9UNM6,Q08209,P28070,P49721,P48556,P28072,P25788,O00231,P51665,P28482,Q04206,Q13153,P45985,P28074,P62195,Q13200 42
Switching of origins to a post replicative state 0.5384273455364439 4.045148618319827 5.228994130157538e-05 0.0701062240535802 0.020106695671043 59 P62191,P33992,P60900,P43686,P62333,Q13200,P25789,P25205,Q15008,P25786,P33993,P20618,P25787,O00487,Q13309,Q13616,Q9H1A4,O14818,O43242,P28066,Q14997,P55036,P49720,P61289,O75832,Q9UNM6,P28070,P49721,P33991,Q9UBD5,P48556,P49736,P28072,P25788,O00231,P51665,Q9UJX4,P20248,Q14566,Q99741,Q9UJX5,P28074,P62195,Q16763 44
Antigen processing ubiquitination proteasome degradation 0.5711385543594419 3.891445404324387 9.964881335511322e-05 0.1293530755100922 0.0277023701127217 91 P62191,Q9Y3I1,Q5T4S7,P60900,Q15369,Q13200,Q92990,Q7Z6Z7,Q93034,Q15008,P25786,P22314,P25787,P20618,O00487,Q14999,Q13309,O14818,P68036,P28066,P49427,Q14997,P61081,P55036,O43242,P61289,P49720,Q8IWV7,P19474,Q13617,P28070,Q15386,P49721,Q9C0C9,Q9UII4,Q9ULT8,Q8TBC4,Q9Y4B6,P61086,Q9UJX4,P55786,Q05086,O95376,O95352,Q7Z7E8,A0AVT1,O94822,P28074,P52888,P62195,Q16763 51
Mitotic g1 phase and g1 s transition 0.5386541091567133 3.778745454170086 0.0001576204405042 0.1967663860128914 0.028654025382573 76 P62191,P33992,P63151,P49643,P43686,P60900,P62333,P25789,P25205,Q15008,P42771,P25786,P33993,P20618,P25787,P31350,O00487,Q13309,P04818,Q13616,P35244,O14818,O43242,P28066,P11802,P55036,P49720,P61289,O75832,P27694,Q9UNM6,P49642,P28070,P49721,P33991,Q9UBD5,P48556,P49736,P28072,P25788,P31751,P51665,O00231,P00374,P20248,P04183,Q14566,Q99741,P30154,Q07864,Q00534,P28074,P14635,Q13200,P62195 55
Apc c mediated degradation of cell cycle proteins 0.5375226119275319 3.735977872279374 0.0001869871117414 0.228899364854023 0.0288791205911837 55 P62191,P60900,P43686,P62333,P53350,P25789,Q13200,Q15008,P25786,P20618,P25787,O00487,Q13309,Q13616,Q9H1A4,O60566,O14818,O43242,P28066,Q14997,O43684,P55036,P49720,P61289,O75832,Q9UNM6,P28070,P49721,P48556,P28072,O14965,P25788,O00231,P51665,Q9UJX4,P20248,Q9UJX5,P28074,P14635,Q16763,P62195 41
Signaling by hedgehog 0.4966370434514534 3.623117710927645 0.0002910732779217 0.332790207261093 0.0362016737461113 58 P68371,P62191,P43686,P60900,P62333,P25789,Q15008,Q9BUF5,P25786,P20618,P25787,O00487,Q13616,O14818,O43242,P28066,Q14997,P55036,P49720,P61289,O75832,Q9UNM6,P28070,P49721,P49407,P48556,P28072,P25788,Q13618,O00231,P51665,P04350,Q9BVA1,P28074,Q13885,P17612,P62195,Q13200 38
Dna replication pre initiation 0.4996450772383568 3.60556189237112 0.000311478241278 0.3514539043752103 0.0362016737461113 61 P62191,P33992,P49643,P60900,P43686,P62333,P25789,P25205,Q15008,P25786,P33993,P20618,P25787,O00487,P35244,O14818,O43242,P28066,Q14997,P55036,P49720,P61289,O75832,P27694,Q9UNM6,P49642,P28070,P49721,P33991,Q9UBD5,P48556,P49736,P28072,P25788,O00231,P51665,Q14566,Q99741,Q07864,P28074,P62195,Q13200 42
Clec7a dectin 1 signaling 0.5519270790125194 3.58242336333768 0.0003404215021323 0.3770359381998652 0.036398914458763 53 P62191,P60900,P43686,P62333,P25789,Q15008,P25786,P20618,P25787,O00487,O15111,Q13616,Q00653,O14818,O43242,P28066,Q14997,P61081,P55036,P49720,O43318,P61289,P49427,O75832,Q9UNM6,Q08209,P28070,P49721,P48556,Q8TBC4,Q14790,P28072,P25788,O00231,P51665,Q04206,P28074,P62195,Q13200 39
Synthesis of dna 0.5247751354467735 3.541691608287942 0.0003975699915437 0.424624363373181 0.0394730205889839 82 P62191,P41440,P33992,P49643,P43686,P35251,P62333,P60900,P25789,P25205,Q15008,Q13200,P25786,P33993,P20618,P25787,P49005,O00487,Q13309,Q13616,Q9H1A4,Q9BRX5,P35244,O14818,O43242,P28066,Q14997,P55036,P49720,P61289,O75832,P27694,P39748,Q9UNM6,P28070,P18858,P49642,P28340,P49721,Q9UBD5,P33991,P49736,P48556,P28072,P25788,O00231,P51665,Q9UJX4,P20248,Q14566,Q99741,Q9UJX5,Q07864,P28074,P62195,Q9BRT9,Q16763 57
Orc1 removal from chromatin 0.5738530697578836 3.521585451780029 0.000428974387022 0.4492103635582505 0.0397516265307102 51 P62191,P33992,P60900,P43686,P62333,P25789,P25205,Q15008,P25786,P33993,P20618,P25787,O00487,Q13309,Q13616,O14818,O43242,P28066,Q14997,P55036,P49720,P61289,O75832,Q9UNM6,P28070,P49721,P33991,Q9UBD5,P48556,P49736,P28072,P25788,O00231,P51665,P20248,Q14566,Q99741,P28074,P62195,Q13200 40
Hedgehog off state 0.5543661634764009 3.4713468195065498 0.0005178546904125 0.513249917195468 0.0409544004856671 52 P68371,P62191,P60900,P43686,P62333,P25789,Q15008,Q9BUF5,P25786,P20618,P25787,O00487,Q13616,O14818,O43242,P28066,Q14997,P55036,P49720,P61289,O75832,Q9UNM6,P28070,P49721,P48556,P28072,P25788,O00231,P51665,P04350,Q9BVA1,P28074,Q13885,P17612,P62195,Q13200 36
Tcr signaling 0.553674532055347 3.4649425526550157 0.0005303447544906 0.5216318991753656 0.0409544004856671 52 P62191,P60900,P43686,P62333,Q13177,P25789,P41240,Q15008,P25786,P20618,P25787,Q16512,O00487,O15111,Q13616,O14818,P19174,O43242,P28066,Q14997,P49427,P55036,P49720,O43318,P61289,O75832,Q9UNM6,P28070,P49721,P48556,P28072,P25788,O00231,P51665,Q04206,Q13153,P28074,P62195,Q13200 39
Interleukin 1 signaling 0.572128196064007 3.272537007563001 0.0010658691791471 0.7728962446971837 0.0779767452112948 49 P62191,P60900,P43686,P62333,P25789,Q15008,P52564,Q02750,P25786,P20618,P25787,O00487,O15111,Q13616,Q00653,O14818,O43242,P28066,Q14997,P55036,P49720,O43318,P61289,O75832,P09429,Q9UNM6,P28070,P49721,P48556,P28072,P25788,O00231,P51665,Q04206,P45985,P28074,Q13501,P62195,Q13200 39
The role of gtse1 in g2 m progression after g2 checkpoint 0.5550793331097776 3.2341599697976604 0.0012200109974931 0.8167402228176889 0.0847907643257731 50 P68371,P62191,P43686,P60900,P62333,P53350,P25789,Q15008,O95067,Q9BUF5,P25786,P20618,P25787,O00487,O14818,O43242,P28066,Q14997,P55036,P49720,P61289,P08238,O75832,Q9UNM6,P28070,P49721,P48556,P28072,P25788,O00231,P51665,P04350,Q9BVA1,P07900,P28074,Q13885,Q15691,P14635,Q13200,P62195 40
Neddylation 0.479512727860883 3.176818958433708 0.0014889995501887 0.8739720793646308 0.0985575892743998 74 P62191,Q9Y3I1,P60900,P43686,Q15369,Q15008,Q93034,O60826,P25786,P20618,P25787,O00487,Q13309,Q14999,Q13619,O14818,O43242,P28066,Q14997,P61081,P55036,P49720,P61289,Q86VP6,P61962,Q13617,Q9Y5A7,P28070,Q99627,P49721,Q5TAQ9,Q8TBC4,Q13618,P61201,Q13564,Q7L5N1,Q92905,P28074,P62195,Q13200 40
Cilium assembly 0.4538154981766534 3.137214675607833 0.001705611931881 0.9067829580175676 0.1077636629688458 59 P68371,Q9UPT5,P53350,Q7Z460,Q96KP1,Q9BT25,P36405,Q9BUF5,P30153,Q3SYG4,Q14008,Q99996,Q15154,P78371,P61163,O43924,O94927,Q9BW83,P49368,Q92973,Q7Z4H7,P50991,P04350,P07437,Q14203,P17987,Q15019,Q9UIS9,Q92538,Q9BVA1,P43034,O75935,P07900,Q14204,Q8TAG9,Q13885,P17612,Q15691,P48643 39
Mapk family signaling cascades 0.4901436318415333 3.092892506664071 0.0019821591836115 0.936577430982621 0.1197913593573939 87 P62191,Q9UQ13,P62993,P31946,P43686,P60900,P62333,Q13177,P25789,P60953,P41240,Q99956,Q15008,P46940,Q02750,P30153,P25786,Q92796,P25787,P20618,Q16512,O00487,O15020,O60725,Q16181,O14818,O14980,O43242,P28066,Q14997,P36507,P55036,P49720,Q96S59,P61289,O75832,Q9UNM6,O43924,O75608,P28070,P49721,P49407,P21359,Q9NZI8,Q13555,P48556,P28072,P25788,Q13618,O00231,P51665,Q15334,Q96P70,Q06124,P35998,Q9HCE1,P30086,P18206,P17980,Q9Y490,P28482,Q13153,P36404,Q99460,P30154,Q14738,P28074,P17612,P62195,Q13200,Q9Y4G8 71
Transcriptional regulation by runx2 0.5170990162956257 3.000725713308664 0.0026933705582252 0.9764548599539424 0.155991044830547 51 P62191,P60900,P43686,P62333,P25789,Q15008,P25786,P20618,P25787,O00487,Q13309,Q13616,O14818,O43242,P28066,Q14997,P11802,P55036,P49720,P61289,O75832,Q9UNM6,P28070,P49721,P48556,P28072,P25788,P31751,P51665,O00231,P28482,P28074,P14635,Q13200,P62195 35
Eukaryotic translation elongation 0.4658850988433671 2.962600627815018 0.0030505208056206 0.9856886814577396 0.1696089567925069 78 Q05639,P84098,P46776,P62861,P62750,P60866,P62906,P62917,P61254,P61247,P50914,P46778,P36578,P29692,P62081,P32969,P62701,P27635,P62847,P08708,P62854,P42766,P39019,P62269,P61513,P47914,P83731,P13639,P05387,P62753,P18621,P62899,P15880,P39023,P62266,P46783,P62841,P26641 38
Degradation of beta catenin by the destruction complex 0.5403869745157147 2.8912157712981004 0.0038375454338512 0.9952254211526124 0.2051610828097418 48 P62191,P60900,P43686,P62333,P25789,Q15008,P25786,P20618,P25787,O00487,Q13616,O14818,O43242,P28066,Q14997,P55036,P49720,P61289,O75832,Q9UNM6,P28070,P49721,P48556,P28072,P25788,O00231,P51665,P30154,Q14738,P28074,P62195,Q13200,Q04727 33
Dna replication 0.4718828107655989 2.8757568529674904 0.0040306006374 0.9963530209347892 0.2075012920735565 88 P62191,P41440,P33992,P49643,P43686,P35251,P62333,P60900,P25789,P25205,Q15008,Q13200,P25786,P33993,P20618,P25787,P49005,O00487,Q13309,Q13616,Q9H1A4,Q9BRX5,P35244,O14818,O43242,P28066,Q14997,P55036,P49720,P61289,O75832,P27694,P39748,Q9UNM6,P28070,P18858,P49642,P28340,P49721,Q9UBD5,P33991,P49736,P48556,P28072,P25788,O00231,P51665,Q9UJX4,P20248,Q14566,Q99741,Q9UJX5,Q07864,P28074,P62195,Q9BRT9,Q16763 57
Dectin 1 mediated noncanonical nf kb signaling 0.585440187328728 2.82795006532751 0.0046847113208785 0.9985366828096522 0.2177464383648266 43 P62191,P60900,P43686,P62333,P25789,Q15008,P25786,P20618,P25787,O00487,O15111,Q13616,Q00653,O14818,O43242,P28066,Q14997,P61081,P55036,P49720,P61289,O75832,Q9UNM6,P28070,P49721,P48556,Q8TBC4,P28072,P25788,O00231,P51665,Q04206,P28074,P62195,Q13200 35
Response of eif2ak4 gcn2 to amino acid deficiency 0.4530193962124682 2.817982862555222 0.0048326389150989 0.9988098213806736 0.2177464383648266 78 P46776,P84098,P62750,P62861,P60866,P62917,P62906,P61254,P61247,P50914,P46778,P36578,P62081,P32969,P62701,P27635,P62847,P08708,P62854,P42766,P08243,P39019,P62269,P61513,P47914,P83731,P05387,P62753,Q92616,P18621,P62899,P15880,P05198,P39023,P62266,P46783,P62841 37
Fceri mediated nf kb activation 0.5534727470016186 2.8164198696027043 0.0048562155318774 0.998848376867487 0.2177464383648266 46 P62191,P60900,P43686,P62333,P25789,Q15008,P25786,P20618,P25787,O00487,O15111,Q13616,O14818,O43242,P28066,Q14997,P49427,P55036,P49720,O43318,P61289,O75832,Q9UNM6,P28070,P49721,P48556,P28072,P25788,O00231,P51665,Q04206,P28074,P62195,Q13200 34
Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1 0.5412516701888259 2.802992419249647 0.0050630859411768 0.9991374056618536 0.2199277955698708 47 P62191,P60900,P43686,P62333,P53350,P25789,Q13200,Q15008,P25786,P20618,P25787,O00487,Q13309,Q9H1A4,O14818,O43242,P28066,Q14997,P55036,P49720,P61289,O75832,Q9UNM6,P28070,P49721,P48556,P28072,O14965,P25788,O00231,P51665,Q9UJX4,Q9UJX5,P28074,P62195,Q16763 36
Signaling by the b cell receptor bcr 0.493992215435697 2.781122759267146 0.0054171248577632 0.9994740331923132 0.227779932483865 51 P62993,P62191,P60900,P43686,P62333,P25789,Q15008,P25786,P20618,P25787,O00487,O15111,Q13616,O00221,O14818,O43242,P28066,Q14997,P55036,P49720,O43318,P61289,O75832,Q9UNM6,Q08209,P28070,P49721,P48556,P28072,P25788,O00231,P51665,Q04206,P28074,P62195,Q13200 36
Tnfr2 non canonical nf kb pathway 0.5771682628136167 2.762700649807997 0.0057325314977212 0.9996615538204164 0.227779932483865 43 P62191,P60900,P43686,P62333,P25789,Q15008,P25786,P20618,P25787,O00487,O15111,Q13616,Q00653,O14818,O43242,P28066,Q14997,P61081,P55036,P49720,P61289,O75832,Q9UNM6,P28070,P49721,P48556,Q8TBC4,P28072,P25788,O00231,P51665,P28074,P62195,Q13200 34
Mismatch repair 0.751404159934222 2.7530489951987356 0.0059043059274088 0.9997338124191756 0.227779932483865 12 P28340,P35244,P49005,P20585,Q9UQ84,P18858 6
S phase 0.4686752358281195 2.7503614432163133 0.0059529561231965 0.9997513181989768 0.227779932483865 94 P62191,P41440,P33992,P49643,P43686,P35251,P62333,P60900,P25789,P25205,Q15008,Q13200,P25786,P25787,P20618,P49005,P33993,O00487,Q13309,Q13616,Q9H1A4,Q9BRX5,P35244,O14818,O43242,P28066,Q14997,P11802,P55036,P49720,P61289,O75832,P27694,P39748,Q9UNM6,P28070,P18858,P49642,P28340,P49721,Q9UBD5,P33991,P49736,P48556,P28072,P25788,O00231,P31751,P51665,Q9UJX4,P20248,Q29RF7,Q14566,Q7Z5K2,Q99741,Q9UJX5,Q07864,P28074,P62195,Q9BRT9,Q16763 61
Regulation of hmox1 expression and activity 0.5549852670922066 2.7429162202271864 0.0060896220178092 0.9997945797643204 0.227779932483865 45 P62191,P60900,P43686,P62333,P25789,Q15008,P68400,P25786,P20618,P25787,O00487,Q13309,Q13616,O14818,O43242,P28066,Q14997,P55036,P49720,P61289,O75832,P67870,Q9UNM6,P28070,P49721,P19784,P48556,P28072,P25788,Q13618,O00231,P51665,P28074,P62195,Q13200 35
Selenoamino acid metabolism 0.4631814243146335 2.7331887916141917 0.0062724367715647 0.9998409267390268 0.227779932483865 91 P46776,P84098,P62750,P62861,Q9P2J5,P60866,P62906,O43252,P61254,P61247,P62917,P00390,P62263,P50914,P56192,P46778,P36578,Q02543,P26373,Q13155,P62829,P54136,P62081,P61313,P32969,P62701,P27635,P62847,P08708,P62854,P07814,P47897,P42766,P62241,P41252,P39019,P62269,P61513,P47914,P23526,P83731,P14868,P49591,P32929,P05387,P62753,P18621,P62899,P15880,P62851,P62280,P39023,P62266,P46783,P62841 55
Nucleotide salvage 0.7465063222344065 2.7154435402839447 0.0066187060888507 0.9999020038660048 0.227779932483865 10 Q08623,Q9P2T1,P00813,Q9BZX2,P00492,Q01433,P07741,P04183 8
Mitotic g2 g2 m phases 0.463808704271359 2.710475131851846 0.0067186886559988 0.9999147984819544 0.227779932483865 93 P68371,P62191,P63151,P43686,P60900,P53350,Q7Z460,P25789,Q15008,O95067,Q9BT25,Q9BUF5,P25786,P20618,P25787,O00487,Q14008,Q99996,O14818,O14980,O43242,P28066,Q14997,P55036,P49720,Q96CW5,P61289,P08238,P28070,P49721,Q7Z4H7,O14965,Q9Y570,P04350,Q9BSJ2,Q14203,P07437,P20248,P30307,Q9UIS9,P43034,O75935,P07900,P30154,P14635,P28074,Q13885,Q14204,Q15691,P62195,Q13200 51
Regulation of pten stability and activity 0.5781209067718542 2.696087309438939 0.0070159274499741 0.9999437952993556 0.2282875924706829 42 P62191,P60900,P43686,P62333,P25789,Q15008,P68400,P25786,P20618,P25787,O00487,O14818,O43242,P28066,Q14997,P55036,P49720,P61289,O75832,P67870,Q9UNM6,P28070,P49721,P19784,P48556,P28072,P25788,P31751,P51665,O00231,P28074,P62195,Q13200 33
Synthesis of active ubiquitin roles of e1 and e2 enzymes 0.7422473953829922 2.693900037220488 0.0070621341555678 0.9999473156856412 0.2282875924706829 10 Q96BN8,P68036,P49427,P61086,Q93008,P45974,P22314,Q16763 8
Tcf dependent signaling in response to wnt 0.421316811842977 2.6825070740616415 0.0073072606350672 0.999962620357598 0.2308430064259884 64 P62191,P60900,P43686,Q15008,P25786,P20618,P25787,O00487,Q9HCK8,P63104,O14818,O14980,O43242,P28066,Q14997,P55036,P49720,P61289,P67870,P28070,P49721,P19784,P40818,Q13618,P31751,P30154,Q14738,P28074,P62195,Q13200,Q04727 31
Interleukin 1 family signaling 0.4581481233077172 2.6583300441166924 0.007852894737709 0.9999825924863136 0.2395316771643153 53 P62191,P60900,P43686,P62333,P25789,Q15008,P52564,Q02750,P25786,P20618,P25787,O00487,O15111,Q13616,Q00653,O14818,O43242,P28066,Q14997,P55036,P49720,O43318,P61289,O75832,P09429,Q9UNM6,P40763,P28070,P49721,P48556,P28072,P25788,O00231,Q06124,Q04206,P45985,Q9UHD2,P28074,Q13501,P62195,Q13200 41
Cellular response to hypoxia 0.5773817504563711 2.620672289152346 0.0087756574819706 0.9999952244555296 0.2571437388745793 41 P62191,P60900,P43686,P62333,Q15369,P25789,Q15008,P25786,P20618,P25787,O00487,O14818,O43242,P28066,Q14997,P55036,P49720,P61289,O75832,Q9UNM6,Q13617,P28070,P49721,P48556,P28072,P25788,O00231,P51665,Q9GZT9,P28074,P62195,Q13200 32
Regulation of runx2 expression and activity 0.5649153554989693 2.592643949302984 0.0095241314672005 0.999998328833574 0.2593598599766946 42 P62191,P60900,P43686,P62333,P25789,Q15008,P25786,P20618,P25787,Q13309,O00487,Q13616,O14818,O43242,P28066,Q14997,P55036,P49720,P61289,O75832,Q9UNM6,P28070,P49721,P48556,P28072,P25788,O00231,P51665,P28074,P62195,Q13200 31
Scf skp2 mediated degradation of p27 p21 0.5814800943051501 2.5862493517843084 0.0097026710207108 0.9999986992474966 0.2593598599766946 40 P62191,P60900,P43686,P62333,P25789,Q15008,P25786,P20618,P25787,Q13309,O00487,Q13616,O14818,O43242,P28066,P11802,P55036,P49720,P61289,O75832,Q9UNM6,P28070,P49721,P48556,P28072,P25788,O00231,P51665,P20248,P28074,P62195,Q13200 32
Cyclin a cdk2 associated events at s phase entry 0.5630441253893597 2.577907077832045 0.0099400723878657 0.999999067902668 0.2606924645119511 42 P62191,P60900,P43686,P62333,P25789,Q15008,P25786,P20618,P25787,O00487,Q13309,Q13616,O14818,O43242,P28066,P11802,P55036,P49720,P61289,O75832,Q9UNM6,P28070,P49721,P48556,P28072,P25788,P31751,P51665,O00231,P20248,P28074,P62195,Q13200 33
Downstream signaling events of b cell receptor bcr 0.5044685199925066 2.5713289313177814 0.0101309052849849 0.9999992869934986 0.2607770064097978 48 P62191,P60900,P43686,P62333,P25789,Q15008,P25786,P20618,P25787,O00487,O15111,Q13616,O00221,O14818,O43242,P28066,Q14997,P55036,P49720,O43318,P61289,O75832,Q9UNM6,Q08209,P28070,P49721,P48556,P28072,P25788,O00231,P51665,Q04206,P28074,P62195,Q13200 35
Mapk6 mapk4 signaling 0.492083123367487 2.5535686513754356 0.0106625256710597 0.9999996620916202 0.2694711033231463 49 P62191,P60900,P43686,P62333,Q13177,P25789,P60953,Q15008,P25786,P20618,P25787,Q16512,O00487,Q16181,O14818,O14980,O43242,P28066,Q14997,P55036,P49720,P61289,O75832,Q9UNM6,P28070,P49721,Q9NZI8,P48556,P28072,P25788,O00231,P51665,P35998,Q9HCE1,P17980,Q13153,Q99460,P28074,P17612,P62195,Q13200 41
Ub specific processing proteases 0.4257560286202986 2.537699568071883 0.0111583728081865 0.9999998316669384 0.2769667536317732 76 P62191,P60900,P43686,P62333,Q96K76,P25789,Q15008,Q14694,P25786,P51784,P20618,P25787,Q13546,O00487,Q13309,Q93009,Q92890,O14818,O43242,P28066,Q14997,P55036,P49720,O43318,P61289,P45974,O75832,Q96FW1,Q9UNM6,Q96RU2,P28070,P49721,P40818,P49407,Q9UPT9,P48556,P28072,P25788,O00231,P20248,O60493,P14735,Q16186,Q86UV5,Q9NZL9,Q9Y4A5,O94966,Q93008,P28074,P62195,Q13200 51
Regulation of ras by gaps 0.5891058379160476 2.5221522845292546 0.0116639201321273 0.9999999173080352 0.2844359470817023 38 P62191,P60900,P43686,P62333,P25789,Q15008,P25786,P20618,P25787,O00487,O14818,O43242,P28066,Q14997,P55036,P49720,P61289,O75832,Q9UNM6,P28070,P49721,P21359,P48556,P28072,P25788,Q13618,O00231,P51665,P28074,P62195,Q13200 31
Hedgehog on state 0.5545281036847346 2.5105935363857848 0.0120528386524036 0.9999999521515772 0.2888525125317437 42 P62191,P60900,P43686,P62333,P25789,Q15008,P25786,P20618,P25787,O00487,O14818,O43242,P28066,Q14997,P55036,P49720,P61289,O75832,Q9UNM6,P28070,P49721,P49407,P48556,P28072,P25788,Q13618,O00231,P51665,P28074,P62195,Q13200 31
Degradation of gli1 by the proteasome 0.5705697312142368 2.503381906752321 0.0123012725018096 0.9999999662676188 0.2897748241185642 40 P62191,P60900,P43686,P62333,P25789,Q15008,P25786,P20618,P25787,O00487,Q13616,O14818,O43242,P28066,Q14997,P55036,P49720,P61289,O75832,Q9UNM6,P28070,P49721,P48556,P28072,P25788,O00231,P51665,P28074,P17612,P62195,Q13200 31
Cdt1 association with the cdc6 orc origin complex 0.5614555055051735 2.497471106958311 0.0125082657892905 0.999999974792952 0.2897748241185642 41 P62191,P60900,P43686,P62333,P25789,Q15008,P25786,P20618,P25787,O00487,O14818,O43242,P28066,Q14997,P55036,P49720,P61289,O75832,Q9UNM6,P28070,P49721,Q9UBD5,P48556,P28072,P25788,O00231,P51665,Q99741,P28074,P62195,Q13200 31
Degradation of dvl 0.5868089774540616 2.4501568579768227 0.0142793993716767 0.9999999979211276 0.2971432407528053 37 P62191,P60900,P43686,P62333,P25789,Q15008,P25786,P20618,P25787,O00487,O14818,O43242,P28066,Q14997,P55036,P49720,P61289,O75832,Q9UNM6,P28070,P49721,P48556,P28072,P25788,Q13618,O00231,P51665,P28074,P62195,Q13200 30
Processive synthesis on the lagging strand 0.6913409824169426 2.440206046258215 0.0146788868529534 0.999999998816614 0.2971432407528053 12 P28340,P49005,P35244,P18858 4
Negative regulation of notch4 signaling 0.5685457019627743 2.427316659642882 0.0152109728229468 0.9999999994414664 0.2971432407528053 39 P62191,P60900,P43686,P62333,P25789,Q15008,P25786,P20618,P25787,O00487,Q13616,P63104,O14818,O43242,P28066,P55036,P49720,P61289,O75832,Q9UNM6,P28070,P49721,P48556,P28072,P25788,O00231,P51665,P28074,P62195,Q13200 30
Metabolism of polyamines 0.5757983447875521 2.4241665342796863 0.0153435675151196 0.9999999995368049 0.2971432407528053 38 P62191,P60900,P43686,P62333,P25789,Q15008,P25786,P20618,P25787,O00487,O14818,O43242,P28066,Q14997,P55036,P49720,P61289,O75832,Q9UNM6,P19623,P28070,P49721,P48556,P28072,P25788,O00231,P51665,P28074,P62195,Q13200 30
Cross presentation of soluble exogenous antigens endosomes 0.585610256367509 2.389823360727892 0.0168564777842696 0.9999999999453586 0.3119556943084979 36 P62191,P60900,P43686,P62333,P25789,Q15008,P25786,P20618,P25787,O00487,O14818,O43242,P28066,Q14997,P55036,P49720,P61289,O75832,Q9UNM6,P28070,P49721,P48556,P28072,P25788,O00231,P51665,P28074,P62195,Q13200 29
Degradation of axin 0.585610256367509 2.389823360727892 0.0168564777842696 0.9999999999453586 0.3119556943084979 36 P62191,P60900,P43686,P62333,P25789,Q15008,P25786,P20618,P25787,O00487,O14818,O43242,P28066,Q14997,P55036,P49720,P61289,O75832,Q9UNM6,P28070,P49721,P48556,P28072,P25788,O00231,P51665,P28074,P62195,Q13200 29
Regulation of runx3 expression and activity 0.5852057532216548 2.386926227892392 0.0169899001879514 0.9999999999547527 0.3119556943084979 36 P62191,P60900,P43686,P62333,P25789,Q15008,P42771,P25786,P20618,P25787,O00487,O14818,O43242,P28066,P55036,P49720,P61289,O75832,Q9UNM6,P28070,P49721,P48556,P28072,P25788,O00231,P51665,P28074,P62195,Q13200 29
Negative regulation of mapk pathway 0.6814483694213007 2.383234054625861 0.0171612793108202 0.999999999964491 0.3119556943084979 11 P31946,P36507,Q99956,Q14738,P28482,P30086 6
Asymmetric localization of pcp proteins 0.5709903200994053 2.334927692114681 0.0195471984311863 0.9999999999987892 0.3313488514554759 37 P62191,P60900,P43686,P62333,P25789,Q15008,P25786,P20618,P25787,O00487,O14818,O43242,P28066,Q14997,P55036,P49720,P61289,O75832,Q9UNM6,P28070,P49721,P48556,P28072,P25788,O00231,P51665,P28074,P62195,Q13200 29
Processive synthesis on the c strand of the telomere 0.669812761701425 2.325348467226142 0.0200533346328457 0.9999999999994093 0.3325713676879427 12 P49005,P35244,P18858 3
Eukaryotic translation initiation 0.4406742355235936 2.316011925355243 0.0205576175744828 0.9999999999997112 0.3325713676879427 102 P49770,P46776,P84098,P62750,P62861,P60866,P62917,P62906,P61254,P61247,P50914,Q15056,Q14232,P46778,Q14152,P62081,P32969,O60841,P62701,P27635,P62847,P08708,P62854,P42766,P39019,P62269,O15371,P61513,P47914,P83731,P55010,Q13144,Q9Y262,Q04637,P05387,P62753,Q14240,P18621,P62899,P15880,P05198,Q9NR50,P06730,P39023,P62266,P46783,O75821,P62841 48
G1 s dna damage checkpoints 0.5365310196595392 2.301972137622654 0.0213367434972435 0.9999999999999044 0.3325713676879427 41 P62191,P60900,P43686,P62333,P25789,Q15008,P42771,P25786,P20618,O96017,P25787,O00487,O14818,O43242,P28066,Q14997,P55036,P49720,P61289,O75832,Q9UNM6,P28070,P49721,P48556,P28072,P25788,O00231,P51665,P20248,P28074,P62195,Q13200 32
Regulation of expression of slits and robos 0.4641234309493209 2.2939846420050536 0.0217913809239238 0.99999999999995 0.3325713676879427 123 P84098,P62861,Q15369,P62333,P61254,P61247,P62906,P50914,P46778,P36578,P25787,O00487,P27635,P28066,P62847,P62241,Q13617,P28070,O00231,P18621,P46776,Q02543,P25786,P62829,P20618,P32969,P62701,P62495,Q14997,P08708,P55036,P42766,P39019,Q9UNM6,P11940,P48556,P28072,P25788,P15170,P51665,P05387,P62899,P15880,P62851,P62280,Q99460,P39023,P62266,P46783,P62841,P62195,Q9BZI7,P62191,P62263,P26373,P61313,O14818,O43242,P62854,P61289,P62269,P61513,P49721,P47914,Q04637,P28074,P62750,P60866,P62917,P43686,P60900,P25789,Q15008,P62081,P49720,O75832,Q9HAU5,P83731,P62753,Q13200 80
Condensation of prometaphase chromosomes 0.6644968741308603 2.2930974895377005 0.0218423928951678 0.9999999999999534 0.3325713676879427 11 O95067,Q15021,Q15003,P67870,Q9NTJ3,P14635,Q9BPX3,P19784 8
Cyclin a b1 b2 associated events during g2 m transition 0.6622322533264839 2.2845640474617235 0.0223384030747419 0.999999999999977 0.3325713676879427 12 P63151,O14980,P30154,Q9Y570,O95067,P20248,P30307,P14635 8
Gap filling dna repair synthesis and ligation in gg ner 0.6522251899170336 2.281028085876651 0.0225467849760012 0.9999999999999828 0.3325713676879427 18 P28340,P35244,Q07864,P49005,P18858 5
Beta catenin independent wnt signaling 0.3779097015970279 2.271452564762543 0.0231195954202951 0.9999999999999925 0.3325713676879427 58 O94973,P62191,P60900,P43686,P62333,P25789,Q15008,P25786,P20618,P25787,O00487,O14818,O43242,P28066,Q14997,P55036,P49720,O43318,P61289,O75832,Q9UNM6,Q08209,P28070,P49721,P48556,P28072,P25788,O00231,P51665,Q9HCE1,Q00610,P28074,P07737,P62195,P09471,Q13200 36
Regulation of mrna stability by proteins that bind au rich elements 0.3834785356105973 2.269989539264924 0.0232082177451298 0.9999999999999932 0.3325713676879427 62 P62191,P31946,P60900,P43686,P25789,Q15008,Q16539,P25786,P20618,P25787,O00487,P63104,O14818,O14980,O43242,P28066,Q14997,P55036,P49720,P61289,O75832,P28070,P49721,Q01105,Q92973,Q04637,Q9Y2L1,P28074,P62195,Q13200 30
Post chaperonin tubulin folding pathway 0.6583202177414264 2.2600356646174857 0.0238190374423132 0.9999999999999972 0.3373515876591558 11 P68371,Q99426,P36404,P04350,Q15813,Q9BUF5,Q13885,Q9BTW9,O75347 9
Cytoprotection by hmox1 0.3878705518658862 2.255322378817858 0.0241131009401294 0.999999999999998 0.3373515876591558 66 O75182,P62191,O75880,P43686,P60900,P62333,P53004,P25789,Q5RI15,Q15008,P68400,P25786,P20618,P25787,Q86X55,O00487,Q13309,Q13616,O14818,O43242,P28066,Q14997,P55036,P49720,P61289,O75832,P67870,Q9UNM6,Q15648,P40763,P28070,P49721,P19784,P30043,P48556,P28072,P25788,Q13618,O00231,P14854,P30519,P28074,P62195,Q13200 44
Nonsense mediated decay nmd 0.4142621860287027 2.23222881686896 0.0255998437659881 0.9999999999999998 0.3378708709135505 87 P46776,P84098,P62750,P62861,P60866,P63151,P62906,P62917,P61254,P61247,P62263,P50914,Q92900,P46778,P36578,Q02543,P30153,P26373,P62829,P62081,P32969,P62701,P27635,P62847,P08708,P62495,P62854,P42766,P62241,P39019,P62269,P61513,Q9UPR3,Q9HAU5,P47914,P11940,P83731,P15170,Q04637,P05387,P62753,P18621,P62899,P15880,P62851,P62280,P39023,P62266,P46783,P62841,Q9BZI7 51
Purine ribonucleoside monophosphate biosynthesis 0.6521349816301546 2.225076818995401 0.0260760816234768 1.0 0.3378708709135505 10 Q06203,P30520,P49915,P20839,P30566,P31939,O15067 7
Interleukin 6 family signaling 0.8519600690909137 2.217942427543054 0.0265587581565833 1.0 0.3378708709135505 4 P40763,P22681 2
Interleukin 6 signaling 0.8519600690909137 2.217942427543054 0.0265587581565833 1.0 0.3378708709135505 4 P40763,P22681 2
Stabilization of p53 0.5329209684477143 2.2127936050136645 0.026911878379092 1.0 0.3378708709135505 40 P62191,P60900,P43686,P62333,P25789,Q15008,P42771,P25786,P20618,O96017,P25787,O00487,O14818,O43242,P28066,Q14997,P55036,P49720,P61289,O75832,Q9UNM6,P28070,P49721,P48556,P28072,P25788,O00231,P51665,P28074,P62195,Q13200 31
Cyclin d associated events in g1 0.6746452518051098 2.183420845395713 0.0290048322290508 1.0 0.3402152650391918 9 P63151,P11802,P42771,Q00534,Q13309 5
Signaling by notch4 0.5127306698037238 2.174550876776673 0.0296637888981525 1.0 0.3402152650391918 42 P62191,P60900,P43686,P62333,P25789,Q15008,P25786,P20618,P25787,O00487,Q13616,P63104,O14818,O43242,P28066,P55036,P49720,P61289,O75832,Q9UNM6,P28070,P49721,P48556,P28072,P25788,O00231,P51665,P28074,P62195,Q13200 30
Synthesis of pc 0.7609531583901743 2.170668321721831 0.0299562534543122 1.0 0.3402152650391918 6 Q9NQZ5,P35790,P67870 3
Hdr through homologous recombination hrr 0.611221148942977 2.165502000402276 0.0303492623711116 1.0 0.3402152650391918 25 P28340,P41440,P35244,P49005,Q07864,O60921,Q9UQ84,Q13535 8
Purine salvage 0.7295263202474483 2.1607337560939457 0.0307159117797584 1.0 0.3402152650391918 7 Q9P2T1,P00813,P00492,Q01433,P07741 5
Vitamin b5 pantothenate metabolism 0.7580755600817861 2.1577037821442984 0.0309508697158578 1.0 0.3402152650391918 6 Q13057,Q9NVE7,P49327 3
Pten regulation 0.381105731908133 2.1411905433754583 0.0322586753367999 1.0 0.3427217888915995 68 P62191,P60900,P43686,P62333,P25789,Q15008,P68400,Q12873,P25786,P20618,P25787,O00487,Q93009,O14818,O43242,P28066,Q14997,P55036,P49720,P61289,O75832,Q15382,P67870,Q9UNM6,P28070,P49721,P19784,P48556,P28072,P25788,P31751,O00231,Q9HCE1,P28482,P28074,P62195,Q13200 37
Netrin 1 signaling 0.6343331451376801 2.1329556617440844 0.0329283635643662 1.0 0.3427217888915995 12 O00401,Q13153,P19174,Q16539,Q14185,Q00169,Q06124,Q16512,P15311 9
G2 m checkpoints 0.4069707040133414 2.131604582782838 0.0330393666989023 1.0 0.3427217888915995 88 P62191,P33992,P31946,P43686,P60900,P62333,P25789,P25205,Q15008,O95067,Q92547,P25786,P20618,P25787,O96017,Q9UQ84,O00487,Q9NXR7,P35244,P27348,P63104,O14818,O43242,P28066,Q14997,P55036,P49720,O60921,P61289,O75832,P27694,P28070,P49721,Q9UBD5,P33991,P49736,P30307,Q13535,Q99741,P14635,P28074,P62195,Q13200 43
Pcna dependent long patch base excision repair 0.6248563074301915 2.123903811400572 0.0336781876310787 1.0 0.3438053293307518 18 P28340,P41440,P35244,Q07864,P49005,P18858 6
Caspase mediated cleavage of cytoskeletal proteins 0.6607941607593035 2.1123167073159297 0.0346592937786645 1.0 0.3438053293307518 9 P55212,P42574,P55210,Q14790 4
Hedgehog ligand biogenesis 0.5246258184486242 2.092000292978342 0.0364384894899858 1.0 0.3438053293307518 39 P62191,P60900,P43686,P62333,P25789,Q15008,P25786,P20618,P25787,O00487,O14818,O43242,P28066,Q14997,P55036,P49720,P61289,O75832,Q9UNM6,P28070,P49721,P48556,P28072,P25788,O00231,P51665,P28074,P62195,Q13200 29
Flt3 signaling 0.7819477150686335 2.090235268223638 0.0365966708611735 1.0 0.3438053293307518 5 P22681,P31751,Q06124 3
Runx1 regulates transcription of genes involved in differentiation of hscs 0.5169801728137617 2.0877071989200338 0.0368242550669233 1.0 0.3438053293307518 40 P62191,Q03164,P60900,P43686,P25789,Q15008,P25786,P20618,P25787,O00487,O14818,O43242,P28066,Q14997,P55036,P49720,P61289,P28070,P49721,P28074,P62195,Q13200 22
Activation of atr in response to replication stress 0.6073992991412288 2.079718356469509 0.0375513733885886 1.0 0.3438053293307518 22 Q9UBD5,O60921,P25205,P35244 4
Maturation of sars cov 2 nucleoprotein 0.7358998733355995 2.0571991691368128 0.0396670714445177 1.0 0.3534437776146133 6 P78362,Q99873 2
Signaling by notch 0.357763658801837 2.0440438701890864 0.040949213409072 1.0 0.3579836895510076 57 P62191,P60900,P43686,P25789,Q15008,P25786,P20618,P25787,O00487,P63104,O14818,O43242,P28066,P55036,P49720,P61289,P28070,P49721,P49407,Q9HCE1,P28074,P67809,Q15398,P62195,Q13200,Q04727 26
Signaling by robo receptors 0.4576301650692044 2.041017357016328 0.0412491018890048 1.0 0.3583515726607298 137 P84098,P62861,Q15369,P62333,P61254,P61247,P60953,Q7Z460,P62906,P50914,P46778,P36578,P25787,O00487,P27635,P28066,P62847,P62241,Q13617,P28070,O00231,P18621,P46776,Q13177,Q02543,P25786,P62829,P20618,Q16512,P32969,P62701,P62495,Q14997,P08708,P55036,P42766,P39019,Q9UNM6,P11940,P48556,P28072,P25788,P15170,P51665,P05387,P62899,P15880,P62851,P62280,Q99460,P39023,P62266,P46783,P62841,P62195,Q9BZI7,P62191,P62263,P26373,P61313,O14818,O43242,P62854,P61289,P62269,P61513,P49721,P47914,Q04637,Q13153,P28074,P07737,P62750,P60866,P62917,P43686,P60900,P25789,Q15008,P62081,P49720,O75832,Q9HAU5,P83731,P62753,P35080,P17612,Q13200 88
Uch proteinases 0.4639776702616915 2.0374751779433606 0.0416024469194695 1.0 0.3591764050811348 46 P62191,P60900,P43686,P25789,Q15008,P85037,P25786,P20618,P25787,O00487,O14818,O43242,P28066,Q14997,P55036,P49720,P61289,P28070,P49721,Q9Y5K5,Q16186,P28074,P62195,Q13200 24
Constitutive signaling by akt1 e17k in cancer 0.7257019775677501 2.0106314970760772 0.0443643945884142 1.0 0.3594469004391438 6 P31751 1
Recycling of eif2 gdp 0.6959437820157307 2.00176906305558 0.0453095746876823 1.0 0.3594469004391438 7 P49770,P05198,Q14232,Q13144 4
Copi mediated anterograde transport 0.3539012980445294 1.996717331075939 0.0458558983473313 1.0 0.3594469004391438 57 P47756,P68371,P53621,Q8N6T3,P54920,Q9BUF5,Q9UBF2,P47755,Q9Y6G9,O15020,P61923,Q14789,P61163,P04350,Q96JB2,Q14203,O43237,P24390,P53618,P48444,Q9NZ32,Q9BVA1,Q92538,Q9Y678,O75935,Q14746,Q13885,Q14204,P35606 29
Transcriptional regulation by runx3 0.4979655775413396 1.9934480644099355 0.0462124052017969 1.0 0.3594469004391438 41 P62191,P60900,P43686,P62333,P25789,Q15008,P42771,P25786,P20618,P25787,O00487,O14818,O43242,P28066,P55036,P49720,P61289,P25440,O75832,Q9UNM6,P28070,P49721,P48556,P28072,P25788,O00231,P51665,P28074,P62195,Q13200 30
Raf independent mapk1 3 activation 0.6864307229864066 1.9562793419100877 0.0504322563637886 1.0 0.3602482725675702 7 P36507,Q99956,Q06124 3
Inositol phosphate metabolism 0.6560182063707389 1.9427381892758455 0.0520477995239427 1.0 0.3653860673650528 8 Q13572,Q96PE3,O15357,P19174,Q01968 5
Cytosolic iron sulfur cluster assembly 0.655057173696743 1.937924902612031 0.0526323852817605 1.0 0.3657950777082355 8 P28340,Q96T76,P18074,Q9Y5Y2 4
Formation of tubulin folding intermediates by cct tric 0.597469173853617 1.9350097753334103 0.0529890961300263 1.0 0.3658459437762534 14 P68371,P49368,Q99832,P50991,P04350,P40227,Q9BUF5,Q13885,P17987,P48643 10
Fanconi anemia pathway 0.6815552808531826 1.932889808101981 0.0532497736721506 1.0 0.3658459437762534 7 P35244 1
Activation of the mrna upon binding of the cap binding complex and eifs and subsequent binding to 43s 0.3987058247686542 1.9280757072560777 0.0538457101068479 1.0 0.3668898874927382 52 P60866,P62861,Q15056,Q14152,P62081,P62701,P62847,P08708,P62854,P39019,P62269,Q9Y262,Q04637,P62753,Q14240,P15880,P05198,P62266,P46783,O75821,P62841 21
Class i mhc mediated antigen processing presentation 0.4243354565652015 1.9194038055238765 0.0549332497075958 1.0 0.3704869385433925 117 P62191,Q9Y3I1,Q5T4S7,P60900,Q15369,Q13200,Q92990,Q7Z6Z7,Q93034,Q15008,P25786,P22314,P25787,P20618,O00487,Q14999,O15111,Q13309,O14818,Q9Y6B6,P68036,P28066,P49427,Q14997,P61081,P55036,O43242,P61289,P49720,P09429,Q8IWV7,P19474,Q13617,P28070,Q15386,P49721,Q9C0C9,Q9UII4,Q9ULT8,Q8TBC4,Q9Y4B6,P61086,Q9UJX4,P55786,Q05086,O95376,O95487,O95352,P60059,Q7Z7E8,A0AVT1,O94822,P28074,P52888,P62195,Q16763 56
Lagging strand synthesis 0.5896840941938118 1.918655093417016 0.0550279982287209 1.0 0.3704869385433925 18 P28340,P41440,P35244,P49005,P18858 5
Nucleotide biosynthesis 0.5945630123042086 1.9150074945268576 0.0554915478406599 1.0 0.3704869385433925 13 P11172,P30520,Q06203,P49915,P20839,P27708,P30566,P31939,O15067 9
Costimulation by the cd28 family 0.5932807137097386 1.911241105422844 0.0559736036769018 1.0 0.3704869385433925 14 P62993,Q13153,Q13177,P30154,P60953,P41240,P31751,Q14738,P30153,Q06124,Q16512 11
Cooperation of prefoldin and tric cct in actin and tubulin folding 0.5897796101785223 1.909970787367685 0.0561369747065536 1.0 0.3704869385433925 17 P68371,P49368,Q99832,Q9BVA1,P50991,P04350,P40227,Q9BUF5,Q99471,Q13885,P17987,P48643 12
G2 m dna replication checkpoint 0.7791883552049762 1.909176054543303 0.0562393841961552 1.0 0.3704869385433925 4 O95067 1
Akt phosphorylates targets in the cytosol 0.7391489896645984 1.900969276414334 0.0573060369837954 1.0 0.3757329783371493 5 P31751 1
Interleukin 3 interleukin 5 and gm csf signaling 0.6468057035497534 1.8965110190443013 0.057892504320743 1.0 0.3769926732618025 8 P62993,P63104,O15357,P46109,Q06124,P22681 6
Activation of the pre replicative complex 0.5815190336006327 1.8929217315009756 0.0583682788063062 1.0 0.3769926732618025 20 Q9UBD5,P25205,P35244,Q07864 4
Nuclear events kinase and transcription factor activation 0.5887066083283478 1.8819794662170688 0.0598388036732795 1.0 0.3769926732618025 13 Q8IV63,Q00535,P50570,P30154,Q16539,Q14738,P28482 7
Dual incision in gg ner 0.5692916954932647 1.8815503728815532 0.0598970897661814 1.0 0.3769926732618025 24 P28340,P41440,P35244,Q92759,Q07864,P18074,P49005 7
Flt3 signaling in disease 0.6967245370185945 1.877152061012656 0.0604972557580334 1.0 0.3769926732618025 6 P22681,P62993,Q92614,Q06124 4
Intracellular signaling by second messengers 0.3878321648531319 1.8757498335232012 0.0606896395109268 1.0 0.3769926732618025 90 P62191,P62993,O43815,P43686,P62333,P60900,P25789,Q15008,P68400,Q12873,P25786,P20618,P25787,O00487,Q93009,O15111,O14818,P19174,O43242,P28066,Q14997,P55036,P49720,P61289,O75832,Q15382,P67870,Q9UNM6,P28070,P49721,P19784,Q13555,P48556,P28072,P25788,O00231,P31751,Q8TBX8,Q06124,Q9HCE1,P28482,Q96B36,P30154,Q14738,P28074,P17612,P62195,Q13200 48
Cellular response to starvation 0.3915070250514548 1.874628614431511 0.0608438337828465 1.0 0.3769926732618025 93 P46776,P84098,P62750,P62861,P36543,P60866,P62906,P62917,P61254,P61247,Q9Y5K8,P50914,P46778,P62081,P32969,P62701,P27635,P62847,P08708,P62854,P42766,P08243,Q15382,P39019,P62269,P61513,P47914,P83731,P05387,P62753,Q92616,P18621,P62899,P15880,P05198,P39023,P62266,P46783,P62841 39
Signaling by type 1 insulin like growth factor 1 receptor igf1r 0.7331939049895424 1.874372123715411 0.060879152932743 1.0 0.3769926732618025 5 Q99570,P31751,O14654,Q06124 4
Regulation of localization of foxo transcription factors 0.6689337560388708 1.8721053619902317 0.0611920283332541 1.0 0.3769926732618025 7 P31946,P31751,P27348 3
Signaling by pdgf 0.6951850058236626 1.870014115677947 0.0614818576882736 1.0 0.3769926732618025 6 P46109,P19174,P40763,Q06124 4
Downstream signal transduction 0.6951850058236626 1.870014115677947 0.0614818576882736 1.0 0.3769926732618025 6 P46109,P19174,P40763,Q06124 4
Assembly and cell surface presentation of nmda receptors 0.5864670501648593 1.867184414853828 0.0618758392619049 1.0 0.3769926732618025 11 P68371,Q13555,P04350,Q15334,Q9BUF5,Q13885,Q92796 7
Map2k and mapk activation 0.5861555425342573 1.86545010990175 0.0621183390665427 1.0 0.3769926732618025 11 P31946,P41240,P36507,P46940,Q9Y490,P28482,P30086,P49407 8
Ctla4 inhibitory signaling 0.6937990761142458 1.863584452836745 0.0623800826260536 1.0 0.3769926732618025 6 P31751,Q06124,Q14738 3
Regulation of tp53 activity 0.3455161451740421 1.859391025820436 0.0629717329160595 1.0 0.3789208171139511 59 P35244,O14965,P31751,P42771,O14744,Q92547,Q9UER7,O60921,P20248,P67870,Q9UQ84,Q13535,P19784 13
Insulin receptor signalling cascade 0.688141250296274 1.8372986404733715 0.0661658204956947 1.0 0.3839585743010401 6 P28482,P31751,Q06124 3
Cytosolic trna aminoacylation 0.5643953341707764 1.832776963012157 0.0668357464035032 1.0 0.3839585743010401 23 Q9P2J5,P26639,O43776,P14868,P49591,P26640,P07814,P41250,P47897,P49589,Q9Y285,P41252,Q13155,P23381,P54136,P54577,Q15181,Q9NSD9 18
Fceri mediated mapk activation 0.6066874790766914 1.8297673671511556 0.0672847324217849 1.0 0.3839585743010401 9 P45985,Q13153,P19174,P28482,Q16512 5
Pcp ce pathway 0.4159363610206154 1.827595120836917 0.0676103386105224 1.0 0.3839585743010401 49 O94973,P62191,P60900,P43686,P62333,P25789,Q15008,P25786,P20618,P25787,O00487,O14818,O43242,P28066,Q14997,P55036,P49720,P61289,O75832,Q9UNM6,P28070,P49721,P48556,P28072,P25788,O00231,P51665,Q00610,P28074,P07737,P62195,Q13200 32
Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand 0.5245365744530586 1.8252893469325728 0.0679573769274561 1.0 0.3839585743010401 33 P47756,P68371,P54652,Q9BUF5,P47755,Q9Y6G9,P08238,P61163,P31689,P0DMV9,P04350,Q14203,P11142,P31948,O43237,Q15185,Q9NZ32,Q9BVA1,O75935,P07900,Q9UJW0,O60884,Q13885,Q14204 24
Dna replication initiation 0.7221017426915717 1.8246697774309864 0.0680508766405734 1.0 0.3839585743010401 5 P49642,Q07864 2
Homologous dna pairing and strand exchange 0.5745213552182578 1.820654679113016 0.0686593654499108 1.0 0.3839585743010401 17 O60921,Q9UQ84,P35244 3
Hdr through single strand annealing ssa 0.5745213552182578 1.820654679113016 0.0686593654499108 1.0 0.3839585743010401 17 O60921,Q9UQ84,P35244 3
Synthesis of pips at the early endosome membrane 0.6839374838275875 1.817729479505377 0.0691054897260725 1.0 0.3839585743010401 6 Q13614,Q08AM6,Q96PE3 3
Mapk targets nuclear events mediated by map kinases 0.5772606658633275 1.8171567156689228 0.0691931205187996 1.0 0.3839585743010401 10 Q8IV63,P30154,Q16539,Q14738,P28482 5
Erk mapk targets 0.5772606658633275 1.8171567156689228 0.0691931205187996 1.0 0.3839585743010401 10 Q8IV63,P30154,Q16539,Q14738,P28482 5
Chk1 chk2 cds1 mediated inactivation of cyclin b cdk1 complex 0.5761711477314019 1.8096849969097133 0.0703446504469642 1.0 0.3839585743010401 12 P31946,P27348,P30307,O96017,P14635 5
Recognition of dna damage by pcna containing replication complex 0.5696402060614261 1.8001673196169037 0.0718342223835915 1.0 0.3840368042815084 18 P28340,P49005,P35244,Q07864 4
Auf1 hnrnp d0 binds and destabilizes mrna 0.4732499654476684 1.7924434289595836 0.0730619633791607 1.0 0.3850004883250387 41 P62191,P60900,P43686,P62333,P25789,Q15008,P25786,P20618,P25787,O00487,O14818,O43242,P28066,Q14997,P55036,P49720,P61289,O75832,Q9UNM6,P28070,P49721,P11940,P48556,P28072,P25788,O00231,P51665,Q04637,P28074,P62195,Q13200 31
Abc transporter disorders 0.4792603978895989 1.7875805337287147 0.0738437084089382 1.0 0.3850004883250387 40 P62191,P60900,P43686,P62333,P25789,Q15008,P25786,P20618,P25787,O00487,O14818,O43242,P28066,Q14997,P55036,P49720,P61289,O75832,Q9UNM6,P28070,P49721,P48556,P28072,P25788,O00231,P51665,P28074,P62195,Q13200 29
Defective cftr causes cystic fibrosis 0.4792603978895988 1.7875805337287147 0.0738437084089382 1.0 0.3850004883250387 40 P62191,P60900,P43686,P62333,P25789,Q15008,P25786,P20618,P25787,O00487,O14818,O43242,P28066,Q14997,P55036,P49720,P61289,O75832,Q9UNM6,P28070,P49721,P48556,P28072,P25788,O00231,P51665,P28074,P62195,Q13200 29
Carboxyterminal post translational modifications of tubulin 0.6501726545150441 1.7811544644196342 0.0748872202193644 1.0 0.3850004883250387 7 P68371,Q14166,P04350,Q9BUF5,Q13885 5
Signaling by fgfr3 0.6500995533770669 1.7807987383552586 0.0749453356248879 1.0 0.3850004883250387 7 P22681,P19174,Q06124 3
Signaling by fgfr4 0.6500995533770669 1.7807987383552586 0.0749453356248879 1.0 0.3850004883250387 7 P22681,P19174,Q06124 3
Signaling by fgfr1 0.6500995533770669 1.7807987383552586 0.0749453356248879 1.0 0.3850004883250387 7 P22681,P19174,Q06124 3
Signaling by scf kit 0.6490953686842809 1.7759111330588355 0.0757475656726067 1.0 0.3870923392828066 7 P40763,P22681 2
Myd88 independent tlr4 cascade 0.5363224939271697 1.756171823439036 0.0790590742693981 1.0 0.3981598305596502 28 Q00653,Q8IV63,Q04206,Q14790,P45985,P30154,Q9UHD2,P52564,Q16539,Q14738,O43318,P09429,P51452,Q06124,P28482,Q13546,O15111 17
Resolution of abasic sites ap sites 0.5487190580795774 1.7516303015851846 0.0798373986726417 1.0 0.3987828822695703 24 P28340,P41440,P35244,Q07864,P29372,P49005,P18858 7
Recruitment of mitotic centrosome proteins and complexes 0.5172721835365641 1.7398960510570332 0.0818772722258407 1.0 0.4035978553183184 32 P68371,P53350,Q7Z460,Q9BT25,Q14008,Q99996,Q96CW5,P61163,Q7Z4H7,P04350,Q9BSJ2,P07437,Q14203,P17612,Q9UIS9,P43034,O75935,P07900,Q14204,Q15691 20
Uptake and actions of bacterial toxins 0.563022344415254 1.7379051317174277 0.0822275313162612 1.0 0.4035978553183184 10 P45985,Q8WUM4,P07900,P36507,P52564,Q02750,P08238,P13639 8
Signaling by ntrk2 trkb 0.7025380553036098 1.736519294125786 0.082472055855193 1.0 0.4035978553183184 5 P19174,Q00535,Q06124 3
Termination of translesion dna synthesis 0.5586563949419507 1.7348245240089784 0.0827718909940804 1.0 0.4035978553183184 18 P28340,P41440,P35244,Q07864,P49005 5
Activation of bad and translocation to mitochondria 0.5875641661167593 1.7282300605026717 0.0839469863759558 1.0 0.4035978553183184 9 P31946,P31751,P27348 3
Apoptotic factor mediated response 0.6391582226226323 1.727443739644538 0.0840880009782609 1.0 0.4035978553183184 7 P42771,P42574,P28482 3
Coenzyme a biosynthesis 0.8851006029839279 1.726798438197465 0.0842038690951887 1.0 0.4035978553183184 3 Q9NVE7 1
Synthesis of ip3 and ip4 in the cytosol 0.7356630824372672 1.720424775878383 0.0853552565919595 1.0 0.4077106758172637 4 Q13572,P19174,O15357 3
Resolution of ap sites via the multiple nucleotide patch replacement pathway 0.550244114429517 1.715465161820369 0.0862599773985497 1.0 0.4085608371979743 21 P28340,P41440,P35244,Q9NX46,P35251,Q07864,P39748,P49005,P18858,P27695 10
Cytochrome c mediated apoptotic response 0.6971609046456559 1.7121875688226902 0.0868621075973736 1.0 0.4085608371979743 5 P42574,P28482 2
Deubiquitination 0.3824830818548601 1.709835560750581 0.0872962851445273 1.0 0.4085608371979743 97 P62191,P43686,Q96K76,P60900,P25789,Q15008,Q14694,P85037,Q14258,P25786,P51784,P20618,P25787,O00487,Q13309,Q9NXR7,O14818,O43242,P28066,Q14997,P55036,P49720,O43318,P45974,P61289,Q96FW1,Q96RU2,P28070,P49721,P40818,P49407,Q9UPT9,Q6GQQ9,P20248,O60493,Q9Y5K5,P14735,Q16186,Q86UV5,O94966,Q93008,P28074,O95630,P62195,Q13200 45
Irs mediated signalling 0.7329749103942556 1.7086802056603954 0.087510202662711 1.0 0.4085608371979743 4 Q99570,P31751,Q06124 3
Dna strand elongation 0.5300850063810706 1.6912966903482327 0.0907801518414506 1.0 0.4161211493687073 27 P28340,P41440,P35244,P25205,P49005,P18858 6
Cd28 co stimulation 0.5791442295711784 1.6832808662065566 0.0923207326397124 1.0 0.4178071416943016 9 P62993,Q13153,Q13177,P60953,P31751,Q16512 6
Polb dependent long patch base excision repair 0.6551026032148914 1.682654574205407 0.0924419802986049 1.0 0.4178071416943016 6 P18858,P39748,Q9NX46,P27695 4
Signaling by csf3 g csf 0.6294538938569233 1.679941811899656 0.0929686376217153 1.0 0.4178071416943016 7 Q93034,P40763,Q06124,Q15369 4
Erks are inactivated 0.6292378741391467 1.678882580089111 0.0931749301677564 1.0 0.4178071416943016 7 Q8IV63,P30154,P28482,Q14738 4
Synthesis of udp n acetyl glucosamine 0.7258064516128943 1.6773165871409563 0.0934805906956315 1.0 0.4178071416943016 4 O95394,Q06210,Q9UJ70 3
Caspase activation via extrinsic apoptotic signalling pathway 0.6505830306139507 1.6613577771753798 0.0966416124609186 1.0 0.4245552827964288 6 P49327,Q14790 2
Signal transduction by l1 0.5496228947164481 1.6604545731104958 0.0968230393140057 1.0 0.4245552827964288 11 Q16512,P36507,P67870,P19784 4
Negative regulation of nmda receptor mediated neuronal transmission 0.6473389308418533 1.646051814647071 0.0997530917372351 1.0 0.4282758582048966 6 Q92796,Q13555,Q15334 3
Gap junction assembly 0.647279674359823 1.6457720895718668 0.0998106905999183 1.0 0.4282758582048966 6 P68371,Q9BUF5,P04350,Q13885 4
Transport of connexons to the plasma membrane 0.647279674359823 1.6457720895718668 0.0998106905999183 1.0 0.4282758582048966 6 P68371,Q9BUF5,P04350,Q13885 4
Darpp 32 events 0.5715629910578531 1.6426927674086225 0.1004465159735161 1.0 0.4282758582048966 9 Q00535,P30154,Q14738,P30153,P17612,Q08209 6
Platelet sensitization by ldl 0.6815423918921606 1.641280360542903 0.1007392309547463 1.0 0.4282758582048966 5 P30154,Q06124,Q14738 3
Recruitment of numa to mitotic centrosomes 0.4839308927754583 1.6412156127437585 0.1007526659230224 1.0 0.4282758582048966 36 P68371,P53350,Q7Z460,Q9BT25,Q9BUF5,Q14008,Q99996,Q96CW5,P61163,O94927,Q7Z4H7,P04350,Q9BSJ2,P07437,Q14203,Q9UIS9,P43034,O75935,P07900,Q14204,Q13885,P17612,Q15691 23
Rna polymerase iii transcription termination 0.6207502867625223 1.6372041588027304 0.1015878183763854 1.0 0.429200813201142 7 Q9NW08,Q9BUI4,O14802,P05455 4
Unwinding of dna 0.5696589330174765 1.6324825236779634 0.1025778771110177 1.0 0.4316636081033088 9 P33991,Q9BRX5,P33992,P49736,P25205,P33993,Q9BRT9 7
Synthesis of pips at the late endosome membrane 0.7153524492234066 1.6314669047942183 0.10279183761309 1.0 0.4316636081033088 4 Q99570,Q08AM6,Q13614 3
Mapk1 erk2 activation 0.8593610032845607 1.6279902557725658 0.1035269519464603 1.0 0.4334411542336743 3 P36507,Q06124 2
Polymerase switching 0.5435509534824026 1.6245709498938432 0.1042540112150265 1.0 0.4339507937029254 13 P28340,P41440,P49005 3
Prolonged erk activation events 0.6181640217204535 1.6244815804239328 0.1042730684149475 1.0 0.4339507937029254 7 P28482,P31946,P36507 3
Trna modification in the nucleus and cytosol 0.536948982285191 1.622460411887532 0.1047048029920616 1.0 0.4344467945043752 20 Q9UBP6,Q9UJA5,Q9NPF4,O60294,Q08J23,Q2VPK5,Q9UET6,Q7Z4G4,Q8TEA1,P57081 10
Retrograde transport at the trans golgi network 0.5418183636993049 1.6182358483973311 0.1056117799483091 1.0 0.4356094187778924 15 Q5VZE5,Q9UID3,Q96JB2,P20645,O60664 5
Signaling by erbb2 0.5419641173782012 1.6156329214156069 0.1061737016692405 1.0 0.4366314950303088 12 P07900,P19174,O60610,Q93034,P31751,P40818 6
Signaling by egfr 0.5381691390318661 1.5939623761219095 0.1109444620630539 1.0 0.4522369567966129 12 P22681,P41240,Q14155,Q06124 4
Constitutive signaling by egfrviii 0.6677621750821708 1.5784550856099604 0.1144610987203051 1.0 0.4558765822957714 5 P62993,P19174,P07900,P22681 4
Constitutive signaling by ligand responsive egfr cancer variants 0.6677621750821708 1.5784550856099604 0.1144610987203051 1.0 0.4558765822957714 5 P62993,P19174,P07900,P22681 4
Signaling by egfr in cancer 0.6677621750821708 1.5784550856099604 0.1144610987203051 1.0 0.4558765822957714 5 P62993,P19174,P07900,P22681 4
Ephrin signaling 0.6316865435771536 1.571988924787673 0.1159531197492751 1.0 0.4592744790675877 6 O00560,Q16512,Q14155,Q13153 4
Dscam interactions 0.7018103791764447 1.5718943017082885 0.1159750662969232 1.0 0.4592744790675877 4 Q16512,Q16539 2
Global genome nucleotide excision repair gg ner 0.455766645632277 1.5513021329570893 0.1208292959263119 1.0 0.4661138218324545 39 P28340,Q86WJ1,P41440,P35244,Q7L5N1,Q92905,Q92759,Q07864,P18074,P61201,P49005,P18858 12
Copi independent golgi to er retrograde traffic 0.5020916891369364 1.5503586386184507 0.1210554602025295 1.0 0.4661138218324545 29 P47756,P68371,Q9NZ32,Q9BVA1,P43034,O75935,P04350,Q14203,Q9BUF5,Q8TD16,P61163,Q13885,Q14204,O43237,P47755,Q15042,Q9Y6G9 17
Activation of nima kinases nek9 nek6 nek7 0.6612284500053607 1.5485900175920353 0.1214803071260164 1.0 0.4664575328871901 5 P53350,P14635,O95067 3
Activation of irf3 irf7 mediated by tbk1 ikk epsilon 0.8371058006509471 1.5421865549002391 0.1230282663460333 1.0 0.4698057423653471 3 Q06124 1
Cd28 dependent vav1 pathway 0.6245237444594745 1.5379878692991362 0.1240515808459803 1.0 0.4711248562183406 6 P62993,Q16512,P60953,Q13153 4
Er to golgi anterograde transport 0.3463825313036169 1.531728548863848 0.1255894343601546 1.0 0.4743731352190625 80 P47756,P68371,P53621,Q8N6T3,P53992,P35606,Q9BUF5,Q9UBF2,P47755,Q9Y6G9,O00743,O15020,Q9Y6B6,O15027,P61923,Q15436,Q14789,P61163,O15084,O95486,Q5H9R7,Q96JB2,P04350,Q14203,O43237,O95487,P24390,P53618,P48444,Q92734,Q9BVA1,Q92538,Q9Y678,O75935,Q9NZ32,Q14746,Q13885,Q14204,P54920,O94979 40
Estrogen dependent nuclear events downstream of esr membrane signaling 0.6901263895015883 1.5203526957027305 0.1284223566412801 1.0 0.4827428844339236 4 P28482,P31751 2
Folding of actin by cct tric 0.5730108939582607 1.5200440518478873 0.1284999044896055 1.0 0.4827428844339236 8 P49368,Q99832,P50991,P40227,P17987,P48643 6
Cd209 dc sign signaling 0.6543172990738032 1.5169512375406229 0.1292789958778231 1.0 0.4842703559964791 5 P17612,Q16512,Q04206,Q13153 4
E2f mediated regulation of dna replication 0.5215532073819855 1.501147797159346 0.1333173385464747 1.0 0.4859814612258394 11 Q9UBD5,P14635,P49642,P30154 4
Bbsome mediated cargo targeting to cilium 0.5928381874958832 1.4994005774736927 0.1337697438830671 1.0 0.4859814612258394 7 P49368,P17987,Q3SYG4,P48643 4
Regulation of tp53 expression and degradation 0.5214946191165692 1.4984831982304492 0.1340077547318541 1.0 0.4859814612258394 12 P30154,P31751,P42771,P20248,Q9UER7 5
Dna damage reversal 0.6502185519987 1.4981657686082115 0.134090186974555 1.0 0.4859814612258394 5 Q6P6C2,Q8N3C0 2
Insulin processing 0.5681214075325554 1.4947878907690817 0.1349698076102812 1.0 0.4859814612258394 8 Q86YB8,Q8TAG9,Q96KP1 3
Transcriptional regulation by runx1 0.329057134909782 1.49275275263304 0.1355019190542505 1.0 0.4859814612258394 69 O75182,P62191,Q03164,P60900,Q15008,P25786,P20618,P25787,O00487,O14818,P28066,Q14997,P55036,P49720,P61289,P67870,Q99873,P28070,P49721,P19784,Q9HCL2,Q06124,Q9HCE1,Q00534,P28074,P62195,Q13200 27
Interleukin 20 family signaling 0.8234751794135751 1.489504722492868 0.1363545107036528 1.0 0.4859814612258394 3 P40763 1
Pyrimidine salvage 0.8220364287847148 1.4839394965056871 0.1378249724820273 1.0 0.4897450133861476 3 Q08623,Q9BZX2 2
Protein folding 0.4469025624573214 1.4809646454023468 0.1386159948813325 1.0 0.4897450133861476 39 P68371,Q9BUR4,Q15813,Q9BUF5,P51784,Q9Y6D5,P67870,Q9BTW9,P61962,O75347,P40763,P19784,P49368,Q99426,Q9Y2T2,P50991,P04350,P40227,Q99471,P17987,Q99832,Q9BVA1,P36404,Q9UHV9,Q13885,Q15477,P48643 27
Ca dependent events 0.6121019590080291 1.4788823903258077 0.1391717505816787 1.0 0.4897450133861476 6 P28482,Q13555 2
E2f enabled inhibition of pre replication complex formation 0.6117359055526705 1.477138181366191 0.1396386005824386 1.0 0.4897450133861476 6 Q9UBD5 1
Mhc class ii antigen presentation 0.3209883008471842 1.4745507670003335 0.140333359470488 1.0 0.4897450133861476 56 P47756,P68371,P53992,P52732,Q9H0B6,Q9BXS5,Q9BUF5,P47755,Q9Y6G9,O15020,Q9Y6B6,Q15436,Q10567,P33176,P61163,Q99661,O95486,P04350,Q14203,O43237,O95487,P50570,Q9BVA1,Q9NZ32,O75935,Q9UJW0,Q00610,Q13885,Q14204,O95239,O94979 31
L1cam interactions 0.4080663865342981 1.4668958628334423 0.14240438614519 1.0 0.4897450133861476 45 O00560,P68371,O94973,P15311,P68400,Q9BUF5,Q92796,Q16512,O15020,P36507,Q96S59,P67870,P35241,P19784,P04350,Q15334,Q96P70,P28482,P50570,Q13153,Q9BVA1,Q00610,Q13885,O95239 24
Negative regulation of fgfr1 signaling 0.6093306023061519 1.4656739540655594 0.1427371331584925 1.0 0.4897450133861476 6 P22681,P28482,Q06124 3
Negative regulation of fgfr2 signaling 0.6093306023061519 1.4656739540655594 0.1427371331584925 1.0 0.4897450133861476 6 P22681,P28482,Q06124 3
Negative regulation of fgfr4 signaling 0.6093306023061519 1.4656739540655594 0.1427371331584925 1.0 0.4897450133861476 6 P22681,P28482,Q06124 3
Negative regulation of fgfr3 signaling 0.6093306023061519 1.4656739540655594 0.1427371331584925 1.0 0.4897450133861476 6 P22681,P28482,Q06124 3
Spry regulation of fgf signaling 0.6093306023061519 1.4656739540655594 0.1427371331584925 1.0 0.4897450133861476 6 P22681,P28482,Q06124 3
Ras processing 0.6774193548387022 1.464172902444056 0.1431467120967235 1.0 0.4897450133861476 4 P36404,O43924,O60725 3
Regulation of plk1 activity at g2 m transition 0.455137879411025 1.461958826125148 0.1437524931378044 1.0 0.4897450133861476 37 P68371,P53350,Q7Z460,O95067,Q9BT25,Q13616,Q14008,Q99996,P61163,Q7Z4H7,O14965,P04350,P07437,Q14203,Q9UIS9,P43034,O75935,P07900,Q14204,P17612,Q15691,P14635 22
Regulation by c flip 0.6748107990850288 1.4526264737497778 0.1463274915169417 1.0 0.4913416282711362 4 Q14790 1
Caspase activation via death receptors in the presence of ligand 0.6748107990850288 1.4526264737497778 0.1463274915169417 1.0 0.4913416282711362 4 Q14790 1
Metabolism of nucleotides 0.3776605896674818 1.4525741093001294 0.1463420389239211 1.0 0.4913416282711362 49 Q08623,P11172,P00813,Q9Y3Z3,P27708,P22392,P31350,P35754,P23921,Q06203,P30520,P00492,P33316,P31939,Q9P2T1,P20839,Q01433,P07741,P04183,Q9BY32,Q9BZX2,P15531,Q9UKK9,P17812,P30566,O15067 26
Mitotic prometaphase 0.3593042821016838 1.4509101945416556 0.1468048687917571 1.0 0.4917078737844396 96 P68371,P53350,Q7Z460,Q9HBM1,Q8TD19,O95067,Q9BT25,Q9BUF5,Q6P1K2,P50748,Q9Y6G9,Q14008,Q99996,O60566,O14980,O43684,Q96CW5,P67870,Q2NKX8,Q99661,P19784,O43683,Q9H900,Q9P258,Q7Z4H7,P04350,Q9BSJ2,Q14203,P07437,Q92674,Q9NTJ3,O43237,Q9UIS9,Q7Z5K2,Q9HC35,P43034,O75935,P07900,P30154,O95347,Q14738,Q15021,Q15003,Q13885,O43264,Q14204,Q15691,P14635,Q9BPX3 49
Sealing of the nuclear envelope ne by escrt iii 0.5115928170274602 1.4443554367103304 0.1486390192279472 1.0 0.4941910103180806 11 P68371,Q9BVA1,P04350,Q9BUF5,Q13885,Q8NC56 6
Long term potentiation 0.6726784636621335 1.443184980676657 0.1489683692973207 1.0 0.4941910103180806 4 Q92796,Q15334 2
Unblocking of nmda receptors glutamate binding and activation 0.6726784636621335 1.443184980676657 0.1489683692973207 1.0 0.4941910103180806 4 Q92796,Q15334 2
Ras activation upon ca2 influx through nmda receptor 0.6726784636621335 1.443184980676657 0.1489683692973207 1.0 0.4941910103180806 4 Q92796,Q15334 2
Ret signaling 0.6378846728413561 1.4415517297740466 0.1494288740874827 1.0 0.4945384166228595 5 P17612,P62993,P19174,Q06124 4
Signaling by flt3 fusion proteins 0.6705534029025779 1.4337731875355555 0.1516369988071639 1.0 0.4977306531100521 4 P62993,Q92614 2
Interleukin 2 family signaling 0.6704041984553126 1.4331122780354453 0.1518257531788935 1.0 0.4977306531100521 4 P40763,O15357 2
Intrinsic pathway for apoptosis 0.5024379403920903 1.4303446030902582 0.1526181392173993 1.0 0.499151090616906 22 P55210,P31946,P27348,Q14790,P31751,P42771,P42574,P28482,P40763 9
Dna double strand break repair 0.3086179821955417 1.4193282934588471 0.155803327086029 1.0 0.503643313138559 58 P28340,P41440,P35244,Q99504,P49005,Q04323,Q07864,O60921,P20248,Q9UQ84,Q13535 11
Tak1 activates nfkb by phosphorylation and activation of ikks complex 0.5734927812696495 1.403370866654097 0.1605062758281916 1.0 0.5152510933052804 7 Q00653,O43318,P09429,O15111 4
Aurka activation by tpx2 0.46612758361494 1.377968108186724 0.1682131348582181 1.0 0.5350486440570323 32 P68371,P53350,Q7Z460,Q9BT25,Q14008,Q99996,P61163,Q7Z4H7,O14965,P04350,P07437,Q14203,P17612,Q9UIS9,P43034,O75935,P07900,Q14204,Q15691 19
Translesion synthesis by y family dna polymerases bypasses lesions on dna template 0.4950714565606595 1.3740233543732423 0.1694344321503593 1.0 0.537702878285387 21 P28340,P41440,P35244,Q07864,P49005 5
Signaling by alk 0.622227001483316 1.3695375454213443 0.1708313069185545 1.0 0.5409009490131909 5 P40763 1
Glutathione synthesis and recycling 0.5887627017334099 1.3674520470683424 0.1714836580262675 1.0 0.5411682778823503 6 Q8WUX2,O75223,P48506,Q96KP4,P48507 5
Rna polymerase iii transcription initiation from type 3 promoter 0.5881036705085807 1.3643003510543483 0.1724730554689792 1.0 0.5411682778823503 6 Q9NW08,Q9BUI4,O14802 3
Rna polymerase iii chain elongation 0.5881036705085807 1.3643003510543483 0.1724730554689792 1.0 0.5411682778823503 6 Q9NW08,Q9BUI4,O14802 3
Transport to the golgi and subsequent modification 0.3347124850296098 1.3619020823772792 0.1732287889388533 1.0 0.5423153527590227 82 P47756,P68371,P53621,Q8N6T3,P53992,P35606,Q9BUF5,Q9UBF2,P47755,Q9Y6G9,O00743,O15020,Q9Y6B6,O15027,P61923,Q15436,Q14789,P61163,O15084,O95486,Q5H9R7,Q96JB2,P04350,Q14203,O43237,O95487,P24390,P53618,P26572,P48444,Q92734,Q9BVA1,Q92538,Q9Y678,O75935,Q9NZ32,Q14746,Q13885,Q14204,P54920,O94979 41
Cellular response to chemical stress 0.3264955194052045 1.3532256365621085 0.17598355755379 1.0 0.5455572412687759 76 O75182,P62191,O75880,P43686,P60900,P62333,P53004,P25789,Q5RI15,Q15008,P00390,P68400,P25786,P20618,P25787,Q86X55,O00487,Q13309,Q13616,O14818,O43242,P28066,Q14997,P55036,P49720,P61289,O75832,P67870,Q9UNM6,Q15648,P40763,P28070,P49721,P19784,P30043,P48556,P30041,P28072,P25788,Q13618,O00231,P14854,P30519,P28074,P62195,Q13200 46
Separation of sister chromatids 0.364747544380337 1.3500132336645947 0.1770117379944014 1.0 0.5455572412687759 108 P68371,P62191,P43686,P60900,Q13200,P53350,Q7Z460,Q9HBM1,P25789,Q15008,Q9BUF5,P25786,Q6P1K2,P20618,P25787,P50748,O00487,Q9Y6G9,Q14008,O60566,O14818,O14980,O43242,P28066,Q14997,O43684,P55036,P49720,P61289,O75832,P28070,P49721,Q99661,Q2NKX8,O43683,Q9H900,Q9P258,P04350,Q9UJX4,Q92674,O43237,Q29RF7,Q7Z5K2,P43034,P30154,Q14738,P28074,O43264,Q13885,Q14204,Q15691,P62195,Q16763 53
Nuclear receptor transcription pathway 0.6491236353221433 1.3387589975983405 0.1806491429066741 1.0 0.5518363075383483 4 P10589 1
Pkmts methylate histone lysines 0.4932705784234742 1.3375779103680523 0.181034069235602 1.0 0.5518363075383483 17 Q03164 1
Inhibition of replication initiation of damaged dna by rb1 e2f1 0.6145256659936187 1.3340785660224035 0.1821781095449113 1.0 0.5525655189760987 5 P30154,P49642 2
Regulation of runx1 expression and activity 0.7829202747088548 1.3324600134947546 0.1827090727685147 1.0 0.5525655189760987 3 Q00534,Q06124 2
Dcc mediated attractive signaling 0.64653738949343 1.3272846073159916 0.1844145537112727 1.0 0.5525655189760987 4 O00401,Q14185 2
Downregulation of erbb2 signaling 0.5570946622478793 1.3217709923800185 0.1862444204299682 1.0 0.5567306331132384 7 P07900,Q93034,P31751,P40818 4
Apoptosis 0.3406400798515645 1.3162359559770411 0.1880948589562807 1.0 0.5610554805777473 90 P62191,P55210,P31946,P60900,Q15008,P42771,P25786,P20618,P25787,O00487,P27348,P63104,O14818,P35611,P28066,Q14997,O00429,P55036,P49720,P61289,P09429,P40763,P28070,P49721,Q14790,P31751,P55212,P49327,P28482,P28074,P42574,P62195,Q13200 33
Diseases of mitotic cell cycle 0.4892129700957885 1.312868905376213 0.1892271262909814 1.0 0.5632242088746559 12 Q9UJX5,P11802,Q9UJX4,Q00534,Q9UER7,Q13309,Q16763 7
Creb1 phosphorylation through nmda receptor mediated activation of ras signaling 0.5318745267111231 1.306924269626773 0.1912384326173684 1.0 0.5653977339561054 8 Q92796,P28482,Q13555,Q15334 4
Tp53 regulates transcription of genes involved in g2 cell cycle arrest 0.4866737236173046 1.3068715686162495 0.1912563335388746 1.0 0.5653977339561054 10 O14965,Q99873,P14635 3
Inactivation of csf3 g csf signaling 0.6080365082614785 1.3041910262357774 0.1921684587812118 1.0 0.5653977339561054 5 P40763,Q15369 2
Formation of incision complex in gg ner 0.4879871172667654 1.3021109084811993 0.1928784746606842 1.0 0.5656140923593904 15 Q86WJ1,Q16531,Q9UGN5,Q13619,P35244,O75925,Q13620,Q92759,P09874,P18074,P27694,P54727 12
Response of eif2ak1 hri to heme deficiency 0.7725859683141175 1.2924375736674694 0.1962056516500752 1.0 0.573168673348937 3 P08243 1
Ncam signaling for neurite out growth 0.5727927248673693 1.2910345543786748 0.1966916958183042 1.0 0.573168673348937 6 O15020,P28482 2
Regulation of lipid metabolism by pparalpha 0.4790659821873173 1.2837761719839018 0.1992202831990672 1.0 0.5769087367639656 22 P11310,Q96EK7,Q9Y2X0 3
Uptake and function of anthrax toxins 0.5686269702427817 1.2710930879370457 0.2036955340493946 1.0 0.5886419798932611 6 P36507,Q02750,P52564,P45985 4
Oncogene induced senescence 0.5465102905283148 1.2690622336998805 0.2044188686504435 1.0 0.5895066959006567 7 P42771,Q00534,P28482,P11802 4
Interleukin 17 signaling 0.4783687732301156 1.262788828545566 0.2066650805660497 1.0 0.5935216156752254 20 Q13616,Q8IV63,P45985,P30154,P52564,Q16539,Q14738,O43318,Q02750,P51452,P28482,Q15418,O15111 13
Nucleotide excision repair 0.3357888356746234 1.261160319173427 0.2072510919289927 1.0 0.5935360864269589 52 P28340,Q86WJ1,P41440,P35244,Q92905,Q92759,Q07864,P18074,P61201,P49005,P18858 11
Mrna capping 0.4798076581494335 1.2540023573729542 0.2098411485925948 1.0 0.5935360864269589 15 O60942,Q92759,P35269 3
Telomere c strand lagging strand synthesis 0.4741994488524723 1.2533026909437366 0.210095569503522 1.0 0.5935360864269589 22 P28340,P41440,P35244,P49005,P18858 5
Wnt mediated activation of dvl 0.7618742446289175 1.250984416268213 0.2109401630898688 1.0 0.5935360864269589 3 P67870 1
Regulation of signaling by cbl 0.6287267061668091 1.2482717713011642 0.2119315482071364 1.0 0.5946255672406363 4 P46109,P22681 2
Ephb mediated forward signaling 0.4785742020456668 1.2475853772822998 0.2121829362239968 1.0 0.5946255672406363 16 O00401,Q13464,Q13153,P61160,P60953,O15145,P23528,O75116,P07947,Q16512,Q92747 11
Heme degradation 0.6276675239364387 1.2435750305249669 0.2136560107125107 1.0 0.5975490038036014 4 P53004,P30519 2
Signaling by moderate kinase activity braf mutants 0.4773939320209304 1.2419771312653975 0.2142449997635593 1.0 0.5975625805474319 13 Q13555,P31946,P41240,P36507,P46940,Q9Y490,P28482,P30086,P49407 9
Transcription coupled nucleotide excision repair tc ner 0.388217474143616 1.235207358635973 0.2167533413042339 1.0 0.5990771644353867 44 P28340,P41440,P35244,Q92905,Q92759,Q07864,P18074,P61201,P49005,P18858 10
Pi3k akt signaling in cancer 0.4755912060060332 1.2345039106889135 0.2170151903879316 1.0 0.5990771644353867 12 O15111,Q96B36,P31751,Q06124 4
Extension of telomeres 0.4435469008833466 1.218251852280398 0.2231282806216941 1.0 0.609328703465923 32 P28340,P41440,P35244,Q9BUR4,P49005,P49642,P18858,O15084 8
Anchoring of the basal body to the plasma membrane 0.4465263651345348 1.215071509901017 0.2243388186159074 1.0 0.6108437268791155 31 P68371,Q14008,Q99996,P43034,O75935,P53350,Q7Z460,Q7Z4H7,P07900,Q14204,P04350,P07437,Q14203,Q9BT25,P61163,P17612,Q15691,Q9UIS9 18
Rho gtpases activate formins 0.2994862037901371 1.2110751409667255 0.2258666077762161 1.0 0.6108437268791155 64 P68371,P53350,Q9HBM1,Q7Z460,Q9BUF5,Q6P1K2,P50748,Q9Y6G9,Q14008,O60566,O14980,O43684,Q99661,Q2NKX8,O43683,Q9H900,Q9P258,P04350,O43237,P43034,O60610,P30154,Q14738,O43264,Q13885,P35080,Q14204,P07737,Q15691 29
Autophagy 0.2985234054755694 1.2058855387579357 0.2278616273199363 1.0 0.6146494290479415 56 Q8NCE2,Q9NT62,P04350,Q99570,Q15382,Q9Y4P1,P67870,Q13501,O43237,O60664,O95352,P19784 12
Abc family proteins mediated transport 0.3448090973543726 1.2006552261953116 0.2298849688972879 1.0 0.6146494290479415 50 P62191,P60900,P43686,P25789,Q15008,P25786,P20618,P25787,O00487,O14818,O43242,P28066,Q14997,P55036,P49720,P61289,O75832,P28070,P49721,P05198,Q8NE71,P28074,P62195,Q13200 24
Fceri mediated ca 2 mobilization 0.5855192868477117 1.200511385274318 0.2299407936006687 1.0 0.6146494290479415 5 P19174,Q08209 2
Translesion synthesis by polk 0.4676372407472392 1.1988184509444892 0.2305985465040885 1.0 0.6152245290608119 10 P35244 1
Signaling by wnt 0.3338846393585081 1.1953580655919502 0.2319471622200564 1.0 0.617532796667084 93 O94973,P62191,O75436,P43686,P60900,P62333,P25789,Q15008,P68400,P25786,P20618,P25787,O00487,Q13616,Q9HCK8,Q96QK1,P63104,O14818,O14980,O43242,P28066,Q14997,P55036,P49720,O43318,P61289,Q9Y3A6,O75832,P67870,Q9UNM6,Q08209,P28070,P49721,P40818,P19784,P48556,P28072,P25788,Q13618,O00231,P31751,O60493,Q9HCE1,Q9Y4A5,P30154,Q14738,Q00610,P28074,P07737,P62195,P09471,Q13200,Q04727 53
Signaling by insulin receptor 0.4692956012758755 1.1943214040318122 0.2323522680984784 1.0 0.617532796667084 17 Q9Y487,Q9Y5K8,P31751,Q06124,P28482 5
Metabolism of nitric oxide nos3 activation and regulation 0.5290450809080541 1.1821361128145034 0.2371516972823792 1.0 0.6261686836818638 7 Q9Y314,P07900,O00401,P50570 4
Toll like receptor tlr1 tlr2 cascade 0.4589415149768736 1.1780527205328368 0.2387755890411966 1.0 0.6274065572159988 24 Q13616,Q00653,Q8IV63,Q04206,P45985,P30154,P52564,Q16539,Q14738,O43318,Q02750,P09429,P51452,P28482,Q15418,O15111 16
Regulation of glycolysis by fructose 2 6 bisphosphate metabolism 0.6126045400238851 1.1768406489472274 0.239259114782131 1.0 0.6274908859380417 4 P17612,P30154,Q14738 3
Mastl facilitates mitotic progression 0.5774995496863085 1.1636376164719564 0.2445709003992073 1.0 0.6368133201409261 5 P30154,P14635,P30153 3
Pecam1 interactions 0.7386969179784478 1.161495167297805 0.2454405873622707 1.0 0.6368526934112324 3 Q06124 1
Wnt ligand biogenesis and trafficking 0.5769345682700949 1.1610417092201502 0.2456249379441393 1.0 0.6368526934112324 5 O75436,Q9Y3A6,Q96QK1,O60493 4
Signaling by braf and raf1 fusions 0.4542231559205976 1.1600317079846612 0.2460358966631883 1.0 0.6368526934112324 25 P31946,Q99996,Q13555,O43252,P41240,P36507,P28482,P51114,O00203,P46940,Q96PU8,Q9Y490,P30086,O95352,P49407 15
Uptake and function of diphtheria toxin 0.6075268817204214 1.1543798095326565 0.2483444891196238 1.0 0.6381098293942095 4 P07900,P08238,P13639 3
Ros and rns production in phagocytes 0.459785906361445 1.154347195786129 0.2483578544620628 1.0 0.6381098293942095 10 Q9Y5K8 1
Diseases of dna repair 0.4594845757440756 1.1526421687169954 0.2490572874309407 1.0 0.6387262537435564 10 Q9UQ84,P20585 2
Dna damage bypass 0.4545157114347333 1.149897500351981 0.2501860905525843 1.0 0.6404395319854369 24 P28340,P41440,P35244,Q07864,P49005 5
Activation of caspases through apoptosome mediated cleavage 0.7346048571805289 1.1457374365307718 0.2519038088204062 1.0 0.6406073671729514 3 P42574 1
Smac xiap regulated apoptotic response 0.7346048571805289 1.1457374365307718 0.2519038088204062 1.0 0.6406073671729514 3 P42574 1
Mtorc1 mediated signalling 0.4588678616195771 1.143282604031259 0.25292127526807 1.0 0.6406073671729514 11 Q96B36,P31946,Q15382,Q04637,P62753 5
Signaling by erythropoietin 0.7327560465810704 1.1386232158515237 0.2548603410407168 1.0 0.6406073671729514 3 P46109,P19174 2
Downstream signaling of activated fgfr1 0.7327560465810518 1.1386232158514515 0.2548603410407468 1.0 0.6406073671729514 3 P19174,Q06124 2
Downstream signaling of activated fgfr2 0.7327560465810518 1.1386232158514515 0.2548603410407468 1.0 0.6406073671729514 3 P19174,Q06124 2
Downstream signaling of activated fgfr3 0.7327560465810518 1.1386232158514515 0.2548603410407468 1.0 0.6406073671729514 3 P19174,Q06124 2
Downstream signaling of activated fgfr4 0.7327560465810518 1.1386232158514515 0.2548603410407468 1.0 0.6406073671729514 3 P19174,Q06124 2
Gab1 signalosome 0.7327560465810501 1.1386232158514449 0.2548603410407497 1.0 0.6406073671729514 3 P41240,Q06124 2
Toll like receptor cascades 0.4284620925026767 1.1366660678479814 0.2556779094832788 1.0 0.6415023360681544 33 P52564,Q16539,Q99570,Q13546,O15111,Q00653,O43318,P09429,P51452,Q8IV63,Q14790,Q06124,P28482,Q04206,P50570,P45985,P30154,Q9UHD2,Q14738 19
Resolution of sister chromatid cohesion 0.2957354483697372 1.1351021832639367 0.2563325069071278 1.0 0.6419859181998336 66 P68371,P53350,Q9HBM1,Q7Z460,O95067,Q9BUF5,Q6P1K2,P50748,Q9Y6G9,Q14008,O60566,O14980,O43684,Q99661,Q2NKX8,O43683,Q9H900,Q9P258,P04350,Q92674,O43237,Q7Z5K2,P43034,P30154,Q14738,O43264,Q13885,Q14204,Q15691,P14635 30
Purinergic signaling in leishmaniasis infection 0.5703615177771195 1.130862093573486 0.2581131400855674 1.0 0.6434732850443518 5 Q00653,Q04206,P08238,Q9Y2Z0 4
Cargo trafficking to the periciliary membrane 0.4580346552054514 1.129676166340411 0.2586127035936498 1.0 0.6434732850443518 18 P49368,Q9UPT5,Q92538,P50991,Q8TAG9,Q96KP1,P36405,O43924,P17987,Q3SYG4,P48643 11
Microrna mirna biogenesis 0.4557620705951447 1.1256192179774596 0.2603267300080827 1.0 0.6434732850443518 11 Q9HAV4 1
Tnfr1 induced proapoptotic signaling 0.6007184657267033 1.1243013723396795 0.2608851963901282 1.0 0.6434732850443518 4 Q6GQQ9,Q14790 2
Negative feedback regulation of mapk pathway 0.6006076177744548 1.1238120759808017 0.2610927573849024 1.0 0.6434732850443518 4 P36507 1
Negative regulation of the pi3k akt network 0.4566178472200065 1.1219636012402574 0.261877916387923 1.0 0.6442660243879875 13 P62993,P30154,P31751,Q14738,Q06124,P28482 6
Homology directed repair 0.3857732809156454 1.1180022692748235 0.2635660241760353 1.0 0.6472734515983908 42 P28340,P41440,P35244,P49005,Q07864,O60921,P20248,Q9UQ84,Q13535 9
Tnf signaling 0.4537765456613296 1.1143371784776877 0.2651345629485799 1.0 0.64945836273882 11 O15111,O43318,Q14790,Q96BN8 4
Transcriptional regulation of white adipocyte differentiation 0.4535353545454717 1.1042249110089428 0.2694955861062866 1.0 0.6526112625221925 13 Q04206,Q86X55,Q9Y2X0,P11802,Q9NPJ6,Q15648,Q96EK7 7
Mitotic spindle checkpoint 0.2815527595789066 1.1025604454257196 0.2702180954491076 1.0 0.6532228742161036 57 P53350,Q9HBM1,Q7Z460,Q6P1K2,P50748,Q9Y6G9,Q9H1A4,Q14008,O60566,O14980,O43684,Q99661,Q2NKX8,O43683,Q9H900,Q9P258,Q9UJX4,Q92674,O43237,Q9UJX5,P43034,P30154,Q14738,O43264,Q14204,Q15691,Q16763 27
Signaling by met 0.4519613732761577 1.0904884231488805 0.2754980501876627 1.0 0.6611695400991412 16 P22681,Q96N67,Q96P70,P40763,P40818 5
Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways 0.4507762601599916 1.0839731230493983 0.2783767158202566 1.0 0.6611695400991412 15 Q00653,Q04206,Q14790,Q16539,O43318,P08238,O15111 7
Egfr downregulation 0.4848928260758538 1.0636496180501236 0.2874874559323865 1.0 0.6666503321715846 8 Q14155 1
Nod1 2 signaling pathway 0.4640877407788073 1.0619057962881926 0.2882784534542555 1.0 0.6667338607344678 9 O15111,O43318,Q14790,Q16539 4
Diseases of immune system 0.5542737586300359 1.0572135918008847 0.2904141180818655 1.0 0.6683371260493264 5 Q00653,P09429,O15111 3
Downregulation of erbb2 erbb3 signaling 0.9432835820895532 1.055610785883384 0.2911460711330205 1.0 0.6689141138428074 2 P31751 1
Diseases of mismatch repair mmr 0.7097641086891445 1.0504803531336542 0.2934973192325678 1.0 0.6732034220020945 3 P20585,P52701 2
Intraflagellar transport 0.4435415592250075 1.0438353984712905 0.2965615509838581 1.0 0.6778361423835731 14 Q9BW83,Q92973,P04350,Q9BUF5,Q13885 5
Generation of second messenger molecules 0.5507869467929454 1.041303253172572 0.2977348273622349 1.0 0.6778361423835731 5 P19174,Q13153,Q16512 3
Rhou gtpase cycle 0.4430039463278277 1.0400061003632248 0.2983370664787435 1.0 0.6778361423835731 18 P62993,Q13153,Q03001,Q13177,P60953,P46940,Q93008,Q00610,Q14155,Q16512,O43396 11
Trna aminoacylation 0.3992840030583358 1.0371335639783923 0.2996736148166961 1.0 0.6778361423835731 37 Q9P2J5,Q13155,P54136,Q15181,P26639,P07814,P47897,P41252,P54577,Q9NSD9,Q96I59,O43776,P49591,P41250,Q5T160,Q9H2U2,P26640,P49589,P23381,Q9Y285 20
Signaling by erbb2 ecd mutants 0.5492084537468944 1.034107824242273 0.3010857588866817 1.0 0.6778361423835731 5 P62993,P19174,P07900 3
Signaling by erbb2 in cancer 0.5492084537468944 1.034107824242273 0.3010857588866817 1.0 0.6778361423835731 5 P62993,P19174,P07900 3
Base excision repair 0.4280415951322225 1.0323178370944706 0.301923247777111 1.0 0.6778361423835731 28 P28340,P41440,P35244,Q07864,P29372,P49005,P18858 7
Signaling by erbb4 0.5183830034222363 1.0313233628692566 0.3023892059886859 1.0 0.6778361423835731 6 P61201,P16949,Q15334 3
Activation of nmda receptors and postsynaptic events 0.4299493161731739 1.0299714692783923 0.3030233988795872 1.0 0.6778361423835731 27 P68371,Q13555,P04350,Q15334,Q9BUF5,Q14155,Q13885,Q92796,P28482,Q14012 10
Traf6 mediated nf kb activation 0.4777821564385169 1.027102824804751 0.3043720486813734 1.0 0.6790965452120531 8 Q00653,Q14258,P09429 3
Antigen processing cross presentation 0.305647638227096 1.0217299444054124 0.3069087344010404 1.0 0.6814746658425658 53 P62191,P60900,P43686,P25789,Q15008,P25786,P20618,P25787,O00487,O15111,O14818,O43242,P28066,Q14997,P55036,P49720,P61289,P09429,P28070,P49721,P60059,P28074,P62195,Q13200 24
Rap1 signalling 0.6972230516572144 1.0027255831170718 0.3159932827704632 1.0 0.6936265718329245 3 P31946,P63104 2
Ionotropic activity of kainate receptors 0.6967435950707329 1.0009053483864565 0.3168725705855446 1.0 0.6936265718329245 3 Q92796 1
Nrcam interactions 0.6967435950707329 1.0009053483864565 0.3168725705855446 1.0 0.6936265718329245 3 Q92796 1
Signaling by ntrk3 trkc 0.6949366749455661 0.9940493598328408 0.3201988374494919 1.0 0.6965201628400529 3 P19174 1
Traf6 mediated irf7 activation 0.5704006161444459 0.9911603509353302 0.3216072876397544 1.0 0.6974011385635861 4 Q14258 1
Oncogenic mapk signaling 0.4163543019430996 0.988298575652049 0.3230064427976287 1.0 0.6980720485205444 30 P21359,P31946,Q99996,P36507,P41240,Q99956,P51114,O00203,Q96PU8,P28482,P30086,O95352,P49407 13
Mtor signalling 0.4334616600345596 0.9824006673815204 0.325902497677331 1.0 0.7012453123397681 17 Q96B36,P31946,P31751,Q15382,Q04637,P62753,Q9Y376 7
Signalling to erks 0.4284830793946381 0.9783728507645248 0.3278899507761204 1.0 0.7033441845351964 10 P31946,P36507,Q16539,P46109,P28482 5
Rho gtpases activate wasps and waves 0.4312121837907651 0.9724919037058324 0.3308058907518569 1.0 0.70359455925136 19 P62993,O00401,Q9UQB8,P61160,P60953,O15145,P28482,Q9NZQ3,Q7L576 9
Regulation of innate immune responses to cytosolic dna 0.5658391265800239 0.971282385077156 0.3314076780545885 1.0 0.70359455925136 4 P19474 1
Bmal1 clock npas2 activates circadian gene expression 0.6867721707972392 0.9631516703807405 0.3354714147090223 1.0 0.7079698867638203 3 Q15648,P43490 2
Diseases of signal transduction by growth factor receptors and second messengers 0.368482293372352 0.9627977449241316 0.335649032645581 1.0 0.7079698867638203 144 P62191,P62993,P31946,P43686,P60900,Q13200,P25789,P41240,Q15008,Q99956,Q92614,P25786,P20618,P25787,O00487,O15111,P22681,Q99996,Q9NR09,O14818,P19174,O43242,P28066,Q14997,P51114,P55036,P36507,Q14789,P61289,P49720,P13984,P33176,Q96PU8,O75832,P31939,P40763,P28070,P49721,P49407,P21359,P35579,Q9H6R7,P31751,Q14203,Q06124,P62753,Q9Y490,P30086,P28482,O95352,Q96B36,Q9HC35,Q92734,P07900,P30154,O00203,P35269,Q14738,P49589,P28074,Q13501,P62195,P26641 63
Dual incision in tc ner 0.4031166390348242 0.958386740878674 0.3378677786965793 1.0 0.7097754679309625 33 P28340,P41440,P35244,Q92759,Q07864,P49005 6
Receptor mediated mitophagy 0.5621265915802149 0.955141762361659 0.3395060120266668 1.0 0.711784851760282 4 P67870 1
Ngf stimulated transcription 0.683003532689886 0.9489373001107068 0.3426525022403108 1.0 0.7156034362622726 3 Q00535 1
Toll like receptor 9 tlr9 cascade 0.4191032532766927 0.9475875972369004 0.3433394426562461 1.0 0.7156034362622726 26 Q00653,Q8IV63,Q04206,P45985,P30154,P52564,Q16539,Q14738,Q99570,O43318,P09429,P51452,P28482,O15111 14
Cell cycle checkpoints 0.3698476860636454 0.9457747743102912 0.3442634745024699 1.0 0.7163566310754989 147 P62191,P33992,P31946,P43686,P60900,P62333,P53350,Q7Z460,P25205,Q9HBM1,P25789,Q15008,O95067,P42771,Q92547,P25786,Q6P1K2,P25787,P50748,Q9UQ84,P20618,O00487,O96017,Q9Y6G9,Q13200,Q9H1A4,Q14008,Q9NXR7,O60566,P35244,P27348,P63104,O14980,O14818,O43242,P28066,Q14997,O43684,P55036,P49720,O60921,P61289,O75832,P27694,O14777,P28070,P49721,Q99661,Q2NKX8,O43683,Q9UBD5,Q9H900,P33991,P49736,Q9P258,Q9UJX4,P20248,Q92674,P30307,O43237,Q13535,Q99741,P43034,Q9UJX5,P30154,Q14738,P14635,P28074,O43264,Q14204,Q15691,P62195,Q16763 73
Telomere maintenance 0.3682569378498406 0.935808120292414 0.349371989836416 1.0 0.7231492310943015 41 P28340,P41440,P35244,Q9BUR4,Q9UER7,P49005,P49642,P18858,O15084 9
Jnk c jun kinases phosphorylation and activation mediated by activated human tak1 0.5574534380619665 0.934876743661984 0.3498518235672216 1.0 0.7231492310943015 4 O43318 1
Foxo mediated transcription 0.4209239304293978 0.9234219765210192 0.3557873434537617 1.0 0.7313080840783428 12 Q96EB6,P31946,P31751,P27348 4
Signaling by ctnnb1 phospho site mutants 0.4951165294856486 0.9216522664850336 0.3567099863346161 1.0 0.7313080840783428 6 Q14738 1
Disassembly of the destruction complex and recruitment of axin to the membrane 0.4951165294856486 0.9216522664850336 0.3567099863346161 1.0 0.7313080840783428 6 Q14738 1
Beta catenin phosphorylation cascade 0.4951165294856486 0.9216522664850336 0.3567099863346161 1.0 0.7313080840783428 6 Q14738 1
Rna polymerase iii transcription 0.4199114488672818 0.9177633307515388 0.3587427837115271 1.0 0.7343924438277212 12 Q9NW08,Q9BUI4,O14802,P05455 4
Interconversion of nucleotide di and triphosphates 0.4220159952810619 0.9158203335098036 0.3597611368387889 1.0 0.7353889360674704 17 Q9Y3D8,Q9H773,P15531,P00568,P33316,P00390,P17812,P30085,P22392,P31350,P35754,P23921,P04818 13
Signaling by ptk6 0.4182319351291855 0.9144270479972478 0.3604924946813272 1.0 0.7353889360674704 11 P22681,P40763,Q14185 3
Signaling by alk in cancer 0.3925513673241786 0.9075505497136226 0.3641157307508482 1.0 0.7387713895900294 34 P62993,P35579,Q9HC35,Q92734,Q9NR09,Q9H6R7,P19174,Q14203,P49589,Q00610,P33176,Q13501,P62753,P28482,P31939,P40763,O94979,P26641 18
Fasl cd95l signaling 0.8982089552238819 0.903101077864897 0.3664722520067398 1.0 0.7393199899298378 2 Q14790 1
Signaling by leptin 0.8979104477611939 0.9021059837574388 0.3670005705407109 1.0 0.7393199899298378 2 P40763 1
Regulation of beta cell development 0.5486031806642321 0.8966726958363922 0.3698935944226811 1.0 0.7403061357668591 4 P31751 1
Dap12 signaling 0.6677904775904895 0.891902950737352 0.3724449529349218 1.0 0.7405915893497147 3 P19174 1
Regulation of tnfr1 signaling 0.4121477341605519 0.8879754541248486 0.374553954935934 1.0 0.7413920981057122 10 O15111,Q6GQQ9,Q14790,Q96BN8 4
Signaling by kit in disease 0.5456989247311683 0.8841902861585955 0.3765935011834611 1.0 0.7413920981057122 4 P07947,P62993,P40763 3
Association of tric cct with target proteins during biosynthesis 0.4159579436136823 0.88262013087456 0.3774415481709747 1.0 0.7413920981057122 19 Q9Y2T2,Q9BUR4,P40763,P51784,Q15477,P61962,P17987,Q9Y6D5,P48643 9
Formation of the early elongation complex 0.4145865471916424 0.8730270525105825 0.3826483326007004 1.0 0.7459764127839742 17 P18074,Q92759,P18615,P35269 4
G protein beta gamma signalling 0.4463225947675224 0.8673072163465935 0.385773703793288 1.0 0.747873707493264 8 P31751 1
Translesion synthesis by polh 0.4109399857757285 0.8626613591491705 0.3883236835206376 1.0 0.7484679148607702 13 P41440,P35244 2
Displacement of dna glycosylase by apex1 0.8859701492537313 0.8624937123023199 0.3884158916510749 1.0 0.7484679148607702 2 P29372 1
Regulation of tp53 activity through phosphorylation 0.3750325438159651 0.8586593253821438 0.3905284972649385 1.0 0.748737394756227 37 P35244,O14965,Q92547,O60921,P20248,P67870,Q9UQ84,Q13535,P19784 9
Molybdenum cofactor biosynthesis 0.53912783751492 0.8560569296012975 0.3919662906518772 1.0 0.7492749116394054 4 O96007,Q9NZB8,Q9Y697 3
Dag and ip3 signaling 0.4439107964415129 0.8552260871207301 0.3924259968874009 1.0 0.7492749116394054 8 P19174,Q13555 2
Deactivation of the beta catenin transactivating complex 0.4070276395480022 0.8526147003767144 0.3938730077444359 1.0 0.7498605353752564 11 Q9HCK8,P31751,P63104,Q04727 4
Negative regulation of flt3 0.8823880597014944 0.8506863695039919 0.3949435968724768 1.0 0.7498605353752564 2 P22681 1
Pd 1 signaling 0.8823880597014924 0.8506863695039862 0.3949435968724799 1.0 0.7498605353752564 2 Q06124 1
The nlrp3 inflammasome 0.4796798824155261 0.8498112173593368 0.395430052107959 1.0 0.7498605353752564 6 Q00653,Q04206,P08238,Q9Y2Z0 4
Inflammasomes 0.4796798824155261 0.8498112173593368 0.395430052107959 1.0 0.7498605353752564 6 Q00653,Q04206,P08238,Q9Y2Z0 4
Pp2a mediated dephosphorylation of key metabolic factors 0.6560361936382422 0.8482675366361441 0.3962889925723152 1.0 0.7504655308930765 3 Q14738 1
Synthesis of diphthamide eef2 0.6537836444793921 0.8399536338115924 0.4009343839750605 1.0 0.7551474169719975 3 Q9BQC3 1
Synthesis of gdp mannose 0.878805970149256 0.838916244225299 0.4015163115214726 1.0 0.7552201258658281 2 P34949 1
Methylation 0.4200098956892839 0.8285480283552431 0.4073602069759265 1.0 0.7631141343619109 9 Q9NZL9,P23526,Q99707,P31153,P78417 5
Tgf beta receptor signaling activates smads 0.4191223382240115 0.8239468909801828 0.4099697352406855 1.0 0.7651829941840071 9 O14980,Q9Y5K5,P61081,P22681 4
Programmed cell death 0.309775273004117 0.8230686021393276 0.410468982582608 1.0 0.7651829941840071 101 P62191,P55210,P41440,P31946,P60900,Q15008,P42771,P25786,P20618,P25787,O00487,P27348,P63104,O14818,P35611,P28066,Q14997,O00429,P55036,P49720,P61289,P09429,P40763,P28070,P49721,Q14790,P31751,P55212,P49327,P28482,P28074,P42574,P62195,Q13200 34
Transport of inorganic cations anions and amino acids oligopeptides 0.4186361168991424 0.8214284299635898 0.411402275216955 1.0 0.7651829941840071 9 Q70HW3 1
Role of second messengers in netrin 1 signaling 0.873134328358212 0.8203591348485277 0.4120114043401719 1.0 0.7651829941840071 2 Q00169 1
Gamma carboxylation hypusine formation and arylsulfatase activation 0.397914911630766 0.8029524102584754 0.4220022415632245 1.0 0.7788546179333645 11 Q9BQC3,O60725,P63241 3
G alpha 12 13 signalling events 0.3989987681069816 0.802310840135368 0.4223731734186393 1.0 0.7788546179333645 12 O75116,Q14155 2
Tp53 regulates transcription of cell cycle genes 0.4021753227129557 0.8021147116399884 0.4224866056991057 1.0 0.7788546179333645 18 O95628,O14965,Q9UIV1,Q92600,P30307,P14635,P20248,Q99873,Q86X55,A5YKK6 10
Synthesis of ip2 ip and ins in the cytosol 0.6422996149193752 0.7978329223931002 0.4249674533312491 1.0 0.7823904107687898 3 Q96PE3 1
Tp53 regulates transcription of cell death genes 0.4501879030790146 0.7964945386121753 0.4257446486116174 1.0 0.7827844729763865 7 P55212,P49327,P24386 3
Smad2 smad3 smad4 heterotrimer regulates transcription 0.49530781758531 0.7925391455719196 0.4280463759900332 1.0 0.783898077342642 5 P28482 1
Signaling by pdgfra transmembrane juxtamembrane and kinase domain mutants 0.6396122455553861 0.7880443458236163 0.4306707671411407 1.0 0.783898077342642 3 P40763 1
Vxpx cargo targeting to cilium 0.4303145582821154 0.7877175036669283 0.4308619648127902 1.0 0.783898077342642 8 Q92538,Q96KP1 2
Met activates ras signaling 0.522730325574019 0.7866007197684194 0.4315156378010061 1.0 0.7840610935207823 4 Q96S59,Q96P70 2
Hiv transcription initiation 0.3982868595353141 0.7847237266351711 0.4326155684439206 1.0 0.7849833254218191 15 P18074,Q92759,P35269 3
Glucuronidation 0.6363093460734448 0.7760513476678209 0.4377186685135537 1.0 0.7898832017028177 3 O60701,Q9NUJ1 2
Synaptic adhesion like molecules 0.4457167023731042 0.7753374371807942 0.4381402931073039 1.0 0.7898832017028177 7 Q92796 1
Signaling by mapk mutants 0.8591044776119432 0.7748980087258474 0.43839992889137 1.0 0.7898832017028177 2 Q99956 1
Nf kb activation through fadd rip 1 pathway mediated by caspase 8 and 10 0.4628370632328193 0.7725885187487419 0.4397659414435364 1.0 0.7898832017028177 6 Q14258,Q14790 2
Activation of bh3 only proteins 0.3934418601079638 0.7721735555008383 0.4400116417110349 1.0 0.7898832017028177 12 P31946,P31751,P27348 3
Signaling by hippo 0.4448267341159674 0.7711403419654113 0.4406237508313111 1.0 0.7898832017028177 7 P42574,Q07157,P31946,Q13043 4
Insulin receptor recycling 0.391465832450748 0.7681939201964436 0.4423719849929814 1.0 0.7898832017028177 11 Q9Y5K8 1
Rhov gtpase cycle 0.3953867223350116 0.763778359171637 0.4449993352381101 1.0 0.7898832017028177 18 O00401,Q13153,Q03001,P60953,Q93008,Q00610,Q14155,Q16512,O43396 9
Signaling by ntrks 0.3744216105599048 0.7635447974809525 0.4451385566260999 1.0 0.7898832017028177 33 Q8IV63,P31946,Q00535,P50570,P19174,P36507,P30154,Q16539,Q14738,P46109,P51452,Q06124,P28482,P40763 14
Gastrin creb signalling pathway via pkc and mapk 0.4876197894322805 0.7590168108758933 0.4478425006031443 1.0 0.7909797659953883 5 P62993,P28482 2
Traf3 dependent irf activation pathway 0.6311656504661631 0.7574601603297997 0.4487742254198348 1.0 0.7910190546139824 3 Q14258 1
Advanced glycosylation endproduct receptor signaling 0.4236774639455195 0.7551798801048402 0.4501410591364461 1.0 0.7910190546139824 8 P28482,P09429 2
Pentose phosphate pathway 0.4406932157994634 0.7517110220197756 0.4522248606251706 1.0 0.7913249789157744 7 P11413,O95336,P11908 3
Aryl hydrocarbon receptor signalling 0.6294416243654891 0.7512531187000903 0.4525003376035243 1.0 0.7913249789157744 3 P08238,O00170 2
Activation of the ap 1 family of transcription factors 0.6290758967998564 0.7499379847854124 0.4532920558272821 1.0 0.7915527105526662 3 P28482 1
Phase ii conjugation of compounds 0.3792072815775033 0.7458815453663945 0.4557389742233646 1.0 0.7948270692226811 30 P21266,O43252,P78417,O60701,P48506,Q96IU4,P10768,P14550,P23526,Q16851,Q99707,P31153,Q9NUJ1,Q96KP4,Q9NZL9,Q8WUX2,O95861,P28161,P48507 19
Telomere extension by telomerase 0.3857353410627729 0.7308318725546886 0.4648818529138452 1.0 0.8037425550995441 12 O00743,P20248,Q9BUR4,O15084 4
Nuclear signaling by erbb4 0.6229448699255309 0.7279769658070229 0.4666276867155003 1.0 0.8037425550995441 3 P16949 1
Fcgamma receptor fcgr dependent phagocytosis 0.3687478482297976 0.7263093398139534 0.4676491549771191 1.0 0.8037425550995441 33 P62993,O00401,P35579,Q13153,Q9UQB8,P07900,P19174,P60953,Q14185,P08238,P28482,Q16512,Q9NZQ3,Q7L576 14
Nervous system development 0.4128340766515848 0.7257800499750705 0.4679736189069268 1.0 0.8037425550995441 222 O00560,P84098,P62861,Q00535,Q15369,P62333,P61254,P61247,P60953,Q7Z460,P62906,P50914,P46778,P36578,Q9BUF5,O75116,P25787,O00487,Q9BPU6,P27635,P28066,P62847,Q96S59,Q00169,P62241,Q13617,P28070,P61160,O00231,Q14155,Q96P70,P18621,P50570,Q9BVA1,O94973,P46776,Q13177,P68400,Q02750,Q02543,P25786,Q92796,P62829,P20618,Q16512,O15020,O00401,P32969,P62701,P62495,Q14997,P08708,P55036,P42766,P67870,Q9UNM6,P39019,Q9NR12,P11940,P48556,P28072,P25788,P15170,P51665,P04035,O15145,P05387,Q15418,P62899,P15880,Q14195,P62851,P62280,Q99460,P39023,P62266,P46783,Q13885,P62841,P62195,Q9BZI7,P62191,P62263,Q16539,P26373,P26038,P07947,O95782,P61313,O14818,O43242,P62854,P61289,P62269,P35241,P61513,P49721,P19784,P47914,P35579,Q15334,Q14185,Q06124,Q04637,Q9Y490,Q13153,P07900,P28074,P07737,P15311,P68371,P62993,P62750,P60866,P62917,P43686,P60900,P25789,Q15008,P62081,P19174,P36507,P49720,P08238,O75832,Q9HAU5,Q13464,P83731,P04350,P62753,P28482,Q00610,P35080,P17612,O95239,Q13200 136
Metalloprotease dubs 0.434739182189249 0.7239209150021587 0.4691142888729114 1.0 0.8037425550995441 7 O95630,O00487 2
Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components 0.3830317233203701 0.7232897427575066 0.4695018932216734 1.0 0.8037425550995441 11 O60566,Q9UJX5,O43684,Q9UJX4,Q16763 5
Apc cdc20 mediated degradation of nek2a 0.3830317233203701 0.7232897427575066 0.4695018932216734 1.0 0.8037425550995441 11 O60566,Q9UJX5,O43684,Q9UJX4,Q16763 5
Transcription of the hiv genome 0.3709074191536556 0.7232530563539696 0.4695244278711006 1.0 0.8037425550995441 32 P29083,Q15369,Q92759,P18615,P35269,P18074,O60942 7
Rho gtpases activate iqgaps 0.382968179900475 0.7161273292228397 0.4739127300950698 1.0 0.807277812294298 12 P68371,P60953,P04350,P46940,Q9BUF5,Q13885 6
Polymerase switching on the c strand of the telomere 0.3851842262846162 0.7101438713892607 0.4776149231289897 1.0 0.8095761231739607 16 P28340,P41440,P49005 3
Adaptive immune system 0.3912496331183107 0.7098651829023915 0.4777877430364561 1.0 0.8095761231739607 197 P53992,Q15369,P62333,Q7Z6Z7,P60953,Q9BUF5,P25787,P47755,O00487,Q14999,Q13616,Q9H1A4,Q9Y6B6,P28066,P49427,Q10567,P61163,Q13617,P28070,Q99661,Q9C0C9,O95486,P29144,Q9Y4B6,P31751,P61086,P55786,Q05086,O95376,O95487,O95352,P50570,P30154,O94822,P52888,Q14204,Q9Y3I1,Q9H0B6,Q9BXS5,P25786,P22314,P20618,Q16512,O15111,O15020,Q14997,P61081,P55036,Q08209,Q15386,Q9UJX4,O43237,P60059,O75935,A0AVT1,Q13885,P62195,P52732,Q16763,P47756,P62191,Q5T4S7,Q92990,Q93034,P63104,O14818,P68036,O43242,O43318,P61289,P33176,P09429,P19474,P49721,Q8TBC4,Q13618,Q14203,Q06124,Q7Z7E8,Q9NZ32,Q13153,P28074,P68371,P62993,P31946,P43686,P60900,P25789,P41240,Q15008,Q13309,Q9Y6G9,O00221,P19174,Q15436,P49720,O75832,Q8IWV7,Q9UII4,Q9ULT8,P04350,Q04206,Q9UJX5,Q14738,Q00610,P17612,O95239,O94979,Q13200 109
Signaling by interleukins 0.3118300024680837 0.6991137025524438 0.4844809758353143 1.0 0.8159103203692175 114 P62191,P62993,O00170,P43686,P62333,P60900,P25789,P60953,Q15008,P52564,Q16539,P25786,P78417,P20618,P25787,O00487,Q53EL6,O15111,P22681,Q00653,P63104,O14818,O43242,P28066,Q14997,Q13126,P55036,O43318,P61289,P49720,Q00169,P09429,P51452,O75832,P40763,P28070,P49721,Q8IV63,O15357,Q99439,Q06124,P28482,P17612,P17987,Q04206,Q9H3K6,P45985,P07900,P30154,Q9UHD2,Q14738,P46109,P28074,Q13501,P42574,P62195,Q13200 57
Golgi cisternae pericentriolar stack reorganization 0.3783231872265836 0.6985227980369886 0.4848503054855926 1.0 0.8159103203692175 11 P14635,O95067 2
Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects 0.8337313432835844 0.6944885849369713 0.4873758570322364 1.0 0.8191686109731664 2 Q00534 1
Parasite infection 0.3788856900558548 0.6865208006299279 0.4923847521129374 1.0 0.8236038573248893 24 Q9Y2A7,P62993,O00401,P35579,Q9UQB8,P61160,P60953,Q14185,O15145,P28482,Q9NZQ3,Q7L576 12
Regulation of kit signaling 0.6109286354135441 0.6854343077049964 0.4930699010950716 1.0 0.8237586088006607 3 P62993,P22681 2
Raf activation 0.3741141133043938 0.6844357656047699 0.4937000378949769 1.0 0.8238211916854957 10 Q9UQ13,Q13555,P31946,P30154,P36507,Q14738,Q02750 7
Telomere c strand synthesis initiation 0.4671962407024033 0.6716139248325336 0.5018295111259801 1.0 0.8328862437745791 5 P49642,P49643 2
Ikba variant leads to eda id 0.4947420197783495 0.6711503286370865 0.5021247679499359 1.0 0.8328862437745791 4 Q00653,O15111 2
Sulfur amino acid metabolism 0.3730649326939963 0.6711444050017282 0.5021285412108614 1.0 0.8328862437745791 11 Q13126 1
Chromosome maintenance 0.3000758178383351 0.669457214747591 0.5032038647339265 1.0 0.8336750559954207 48 P28340,P41440,P35244,Q9BUR4,Q9UER7,P49005,P49642,P18858,O15084 9
Regulation of gene expression in beta cells 0.8232835820895563 0.6621446907596791 0.5078784967457359 1.0 0.8384217464092315 2 P31751 1
Cooperation of pdcl phlp1 and tric cct in g protein beta folding 0.3744119301234314 0.6599622700678379 0.509278041983233 1.0 0.8397348497706927 14 P49368,Q99832,P50991,P40227,P67870,P17987,P48643,P19784 8
Constitutive signaling by overexpressed erbb2 0.4901327071781248 0.6525934042508204 0.5140184388626661 1.0 0.8462479376723493 4 P62993,P07900 2
Phosphorylation of the apc c 0.3693381366578198 0.6519309951377882 0.5144456887288742 1.0 0.8462479376723493 11 Q9UJX5,P53350,Q9UJX4,P14635,Q16763 5
Myoclonic epilepsy of lafora 0.8191044776119407 0.6493445019476085 0.5161157273028001 1.0 0.8469903907330485 2 P13807 1
Rho gtpases activate rocks 0.3707189258455503 0.645915433345444 0.5183341240635779 1.0 0.8476287440569098 13 O75116 1
Dna repair 0.304172723074476 0.6448796021115704 0.5190052113088026 1.0 0.8477288410331794 112 P41440,P18074,Q14258,Q92547,P49005,Q9UQ84,P35244,Q99504,Q04323,O60921,P29372,P18858,P28340,Q92759,P20248,P20585,P52701,P61201,Q8TAT6,Q7L5N1,Q13535,Q86WJ1,Q92905,Q6P6C2,Q07864,P27695 26
Rna polymerase iii transcription initiation from type 1 promoter 0.3657834411928192 0.6337613799767152 0.5262365606736583 1.0 0.8529406111945347 11 Q9NW08,Q9BUI4,O14802 3
Aggrephagy 0.3715771663219352 0.6333709989844797 0.5264913988524538 1.0 0.8529406111945347 18 P68371,P07900,P04350,Q9BUF5,Q13885,Q14204,O43237 7
Activation of ampk downstream of nmdars 0.3626371016378905 0.625750576971816 0.5314785535401523 1.0 0.8587247762218388 10 P68371,Q9BUF5,P04350,Q13885 4
Phosphorylation of emi1 0.5912212600776348 0.6172717131487332 0.5370555212914876 1.0 0.8634485823286818 3 P53350,P14635 2
Signal attenuation 0.5911007780024423 0.6168617525435308 0.5373259163412301 1.0 0.8634485823286818 3 P28482 1
Met activates rap1 and rac1 0.4530719433438621 0.6128403152111754 0.5399819309062557 1.0 0.8667146466047292 5 P46109,Q96N67 2
Glycogen synthesis 0.4252709204193677 0.6065755341126027 0.5441326408509779 1.0 0.8703617615452925 6 P13807,P46976,P36871 3
Glutathione conjugation 0.3622284320339294 0.5925545821498248 0.5534792820708447 1.0 0.8827469804707153 15 P10768,P14550,Q8WUX2,P48506,Q96KP4,P78417,P28161,P48507 8
Nostrin mediated enos trafficking 0.7991044776119411 0.5892612292144864 0.5556860488574646 1.0 0.8827469804707153 2 P50570 1
Factors involved in megakaryocyte development and platelet production 0.2844823934882448 0.5845991921604706 0.5588172510136895 1.0 0.8851714972578489 49 P47756,P68371,Q00535,Q9H0B6,Q9BUF5,Q96Q89,P47755,O60333,Q13572,Q96N67,P33176,Q99661,P04350,Q14185,Q9H4M9,Q13885,P17612,O95239,P52732 19
Mrna decay by 3 to 5 exoribonuclease 0.3605744612432726 0.5841450681156233 0.5591227155340945 1.0 0.8851714972578489 15 Q9Y2L1,Q15477,Q96C86 3
Growth hormone receptor signaling 0.4446646881219163 0.5786198334383191 0.5628457190910434 1.0 0.8900518197230379 5 P40763 1
Alk mutants bind tkis 0.4157786503561506 0.5664155944497654 0.5711112962343345 1.0 0.8962514908207826 6 Q9HC35 1
Aberrant regulation of mitotic exit in cancer due to rb1 defects 0.3658329486315998 0.5599985224721633 0.5754804455077636 1.0 0.8993635967495027 9 Q9UJX4,Q13309,Q16763,Q9UJX5 4
Transferrin endocytosis and recycling 0.3523463635796444 0.5594545936312871 0.5758515115878111 1.0 0.8993635967495027 12 Q9Y5K8 1
Ripk1 mediated regulated necrosis 0.3540529012499991 0.5560599685406605 0.5781698600196266 1.0 0.9006054057642159 14 O00560,P41440,Q14790,P07900,P49327,Q13546,Q16543 7
Mapk3 erk1 activation 0.4654221976516519 0.5558203122408388 0.5783336982824165 1.0 0.9006054057642159 4 Q02750,Q06124 2
Crmps in sema3a signaling 0.3963421345993461 0.5516743786372901 0.5811714670233488 1.0 0.9026014962708993 7 Q9BPU6 1
Signaling by wnt in cancer 0.3794800733420669 0.5481330916609444 0.5836005199459242 1.0 0.9038940487950268 8 Q14738 1
Kinesins 0.3539512859708237 0.5422122743265299 0.5876722805887395 1.0 0.9038940487950268 22 P68371,Q9H0B6,Q99661,P04350,Q9BUF5,P33176,Q96Q89,Q13885,P52732,O60333 10
Polo like kinase mediated events 0.3939257821919872 0.5413233183481072 0.5882847507149662 1.0 0.9038940487950268 7 P14635,O95067 2
Regulation of bach1 activity 0.5682293221857342 0.5407124863157835 0.5887057707687484 1.0 0.9038940487950268 3 Q13616,Q13309 2
Prolactin receptor signaling 0.5682293221857324 0.5407124863157774 0.5887057707687526 1.0 0.9038940487950268 3 Q13616,Q06124 2
Biological oxidations 0.2975570205106222 0.5352246685521446 0.5924945101400869 1.0 0.906649768652434 45 P21266,O00170,O43252,P78417,O60701,P48506,P07099,P11766,P08238,Q96IU4,O43488,P10768,P14550,P23526,Q16851,Q86WA6,P30837,Q99707,P31153,Q9NUJ1,Q96KP4,P51580,Q9NZL9,Q8WUX2,O95861,P28161,P48507 27
Hiv transcription elongation 0.3494372241096043 0.5282260031649507 0.5973424834288106 1.0 0.9104233025943492 25 Q15369,Q92759,P18615,P35269,P18074 5
Nephrin family interactions 0.3740420153431571 0.5241279553288254 0.6001895459185544 1.0 0.9132471109241586 8 P46940,O00401,Q9Y5K6 3
Nuclear events stimulated by alk signaling in cancer 0.3444377406510275 0.5211560415462873 0.6022580737611756 1.0 0.9132471109241586 12 Q9HC35,Q00610,P33176,P62753,P28482,P40763 6
Signaling by vegf 0.3397372983978913 0.5208370536051279 0.6024802882859377 1.0 0.9132471109241586 31 O75116,P31751,Q9UQB8 3
Metabolism of cofactors 0.4298229184666746 0.5197954619840639 0.6032061426087845 1.0 0.9133289902938532 5 P00374,O75874 2
Zbp1 dai mediated induction of type i ifns 0.3727766769350134 0.5185982534835348 0.6040409272621998 1.0 0.9133289902938532 8 Q00653,Q9UHD2,Q04206,O15111 4
Clec7a inflammasome pathway 0.5611685106790586 0.5179322803562137 0.6045055187556438 1.0 0.9133289902938532 3 Q14790 1
Processing of dna double strand break ends 0.3416210767910267 0.5120930643685675 0.6085858783331752 1.0 0.9159723761750086 29 O60921,Q9UQ84,P35244 3
Activated tak1 mediates p38 mapk activation 0.4024760990902408 0.5116582012000357 0.6088902445802342 1.0 0.9159723761750086 6 O43318,Q16539 2
Metabolic disorders of biological oxidation enzymes 0.4003279798033881 0.5029976839370056 0.6149659005187176 1.0 0.9159723761750086 6 P48506,P23526,P51580,P48507 4
Apc c cdc20 mediated degradation of cyclin b 0.3373638383452163 0.5028342061679109 0.615080842033844 1.0 0.9159723761750086 10 Q9UJX4,P14635,Q16763,Q9UJX5 4
Vegfr2 mediated vascular permeability 0.3389468273416224 0.5023254816340416 0.61543858761578 1.0 0.9159723761750086 11 P31751 1
Transcriptional activity of smad2 smad3 smad4 heterotrimer 0.3532036825563426 0.50226557821301 0.6154807189550058 1.0 0.9159723761750086 9 Q93008,P28482,Q9UPN9 3
Map3k8 tpl2 dependent mapk1 3 activation 0.3988203290609972 0.4969512652882079 0.6192234187048602 1.0 0.9205567401066904 6 Q13616,P45985,O15111 3
Cytosolic sensors of pathogen associated dna 0.3440824214786414 0.4936016255860246 0.6215875525222749 1.0 0.9228571998694468 23 Q00653,Q9BUI4,O14802,Q04206,Q9UHD2,O15160,P19474,Q9NW08,P13010,O15111 10
Intra golgi and retrograde golgi to er traffic 0.266031143621334 0.489331187122198 0.6246072448967737 1.0 0.925590693397138 92 P47756,P68371,P53621,Q8N6T3,Q9UID3,P52732,Q9H0B6,P20645,Q9BUF5,Q9UBF2,Q96Q89,P47755,O60333,P61923,P33176,Q99661,Q96JB2,P04350,Q14203,O43237,P24390,P53618,P48444,Q5VZE5,Q92538,P43034,O75935,Q9NZ32,Q14746,Q8TD16,O43264,Q13885,O60664,Q14204,P54920,Q15042 36
Ddx58 ifih1 mediated induction of interferon alpha beta 0.3434728337974399 0.4877456561484808 0.6257300083590045 1.0 0.9262669985293038 20 Q00653,Q9UII4,Q04206,Q13526,Q14790,P07900,Q9UHD2,P61086,Q14258,P08238,P09429,O15111 12
Rho gtpase effectors 0.2991526990195289 0.4795538028727618 0.631544702186206 1.0 0.9290616385535798 125 P68371,P62993,P31946,Q9UQB8,P53350,Q7Z460,Q9HBM1,Q9H0B6,Q16539,Q99570,Q9BUF5,Q6P1K2,O75116,Q16512,P50748,Q9NZQ3,Q9Y6G9,O00401,Q14008,O60566,P27348,P63104,O14980,Q9HD26,O43684,P33176,Q2NKX8,Q99661,O43683,P35579,Q9H900,Q13526,Q13464,Q9P258,P04350,Q15334,P30307,O43237,P28482,Q16513,Q13153,P43034,P30154,O60610,Q15058,Q14738,O43264,Q13885,P35080,Q14204,P07737,Q15691 52
Tetrahydrobiopterin bh4 synthesis recycling salvage and regulation 0.5483519553980738 0.4775577396178534 0.6329650156188777 1.0 0.9290616385535798 3 P00374 1
Amino acids regulate mtorc1 0.3375164899036859 0.4716785347250427 0.6371562608205792 1.0 0.9301591277025008 15 Q15382 1
Gap junction trafficking and regulation 0.3351659018636518 0.4712547480099558 0.6374588265504779 1.0 0.9301591277025008 13 P68371,P50570,Q9BVA1,P04350,Q00610,Q9BUF5,Q13885,Q9UM54 8
Negative regulation of met activity 0.3609248619710806 0.4678971120200067 0.6398581688456071 1.0 0.9301591277025008 8 P22681 1
Runx3 regulates p14 arf 0.7558208955223924 0.4668987011995662 0.6405723545714057 1.0 0.9301591277025008 2 P42771 1
Signaling by receptor tyrosine kinases 0.2901605085151252 0.4631468559287114 0.643259106188357 1.0 0.9301591277025008 118 P62993,P31946,P36543,Q00535,Q9UQB8,P60953,Q9Y5K8,Q93034,Q16539,P41240,Q99570,Q93050,O75116,Q16512,P22681,Q96N67,Q9Y487,P19174,P36507,Q96S59,P13984,P16949,P51452,P40763,P40818,Q8IV63,Q13464,Q13043,P31751,Q15334,Q14185,Q14155,Q96P70,Q06124,P61201,P28482,P50570,Q13153,P07900,P30154,O60610,P35269,Q14738,P46109,Q00610,O14654,P17612 47
Protein ubiquitination 0.335884694014272 0.4624614824261951 0.6437504178775582 1.0 0.9301591277025008 26 Q96BN8,P68036,P49427,P61086,Q93008,P45974,Q5VTR2,P22314,Q14527,Q16763 10
Arachidonic acid metabolism 0.4144846262724602 0.4614185677379951 0.6444983326084515 1.0 0.9302727750007762 5 Q8N8N7 1
G1 s specific transcription 0.3290347226705887 0.456790265726186 0.6478218031305587 1.0 0.9312086120292068 11 P00374,Q99741,P31350,P04183 4
Cd163 mediating an anti inflammatory response 0.7513432835820918 0.4549206983478431 0.649166291407411 1.0 0.9312086120292068 2 Q16539 1
Vitamin b2 riboflavin metabolism 0.7495522388059725 0.4501683608188393 0.6525890479457408 1.0 0.9332291940787856 2 Q969G6 1
G2 m dna damage checkpoint 0.3094706541550722 0.4449169791432008 0.656379751840362 1.0 0.9376748750928084 38 P31946,P35244,Q92547,O60921,P14635,Q9UQ84,Q13535 7
Triglyceride metabolism 0.368612749099792 0.4373030218047654 0.6618916041581122 1.0 0.939764381797524 7 P17612,Q9HCL2,O60664 3
Budding and maturation of hiv virion 0.3518091708313179 0.4303480280542384 0.6669424950651421 1.0 0.9417369745164336 8 Q8WUM4,O75351,Q9H9H4,Q9UN37 4
Rho gtpases activate nadph oxidases 0.3660124600874127 0.4271212369823461 0.6692910254582887 1.0 0.9417369745164336 7 Q99570,P28482,Q16539 3
Iron uptake and transport 0.3299271457224392 0.4245201221868726 0.6711865335248546 1.0 0.9417369745164336 19 Q13616,P36543,Q9Y487,P30519,Q9Y5K8,Q93050,Q86VP6,P21399 8
Golgi to er retrograde transport 0.237204250823407 0.419797134803996 0.6746336581765031 1.0 0.9417369745164336 73 P47756,P68371,P53621,Q8N6T3,P52732,Q9H0B6,Q9BUF5,Q9UBF2,Q96Q89,P47755,O60333,P61923,P33176,Q99661,P04350,Q14203,O43237,P24390,P53618,P48444,Q9NZ32,Q92538,P43034,O75935,Q8TD16,O43264,Q13885,Q14204,P54920,Q15042 30
Condensation of prophase chromosomes 0.3211888406195355 0.4151060169917865 0.678064294889789 1.0 0.9417369745164336 12 Q6IBW4,Q01105,P42695,O95347,Q9NTJ3,P14635 6
Regulation of mecp2 expression and activity 0.3317487213593394 0.4100742186266888 0.6817515043104818 1.0 0.9417369745164336 9 Q9HCE1,Q13555,P42858 3
Activated ntrk2 signals through frs2 and frs3 0.7325373134328397 0.4061704608792585 0.6846173566604405 1.0 0.9417369745164336 2 Q06124 1
Frs mediated fgfr4 signaling 0.7325373134328397 0.4061704608792585 0.6846173566604405 1.0 0.9417369745164336 2 Q06124 1
Signaling by flt3 itd and tkd mutants 0.7325373134328397 0.4061704608792585 0.6846173566604405 1.0 0.9417369745164336 2 Q06124 1
Stat5 activation downstream of flt3 itd mutants 0.7325373134328397 0.4061704608792585 0.6846173566604405 1.0 0.9417369745164336 2 Q06124 1
Pi 3k cascade fgfr4 0.7325373134328397 0.4061704608792585 0.6846173566604405 1.0 0.9417369745164336 2 Q06124 1
Frs mediated fgfr3 signaling 0.7325373134328397 0.4061704608792585 0.6846173566604405 1.0 0.9417369745164336 2 Q06124 1
Stat5 activation 0.7325373134328397 0.4061704608792585 0.6846173566604405 1.0 0.9417369745164336 2 Q06124 1
Tie2 signaling 0.7325373134328397 0.4061704608792585 0.6846173566604405 1.0 0.9417369745164336 2 Q06124 1
Pi 3k cascade fgfr3 0.7325373134328397 0.4061704608792585 0.6846173566604405 1.0 0.9417369745164336 2 Q06124 1
Pi 3k cascade fgfr1 0.7325373134328397 0.4061704608792585 0.6846173566604405 1.0 0.9417369745164336 2 Q06124 1
Frs mediated fgfr2 signaling 0.7325373134328397 0.4061704608792585 0.6846173566604405 1.0 0.9417369745164336 2 Q06124 1
Frs mediated fgfr1 signaling 0.7325373134328397 0.4061704608792585 0.6846173566604405 1.0 0.9417369745164336 2 Q06124 1
Pi 3k cascade fgfr2 0.7325373134328397 0.4061704608792585 0.6846173566604405 1.0 0.9417369745164336 2 Q06124 1
Interleukin 15 signaling 0.7325373134328399 0.4061704608792582 0.6846173566604408 1.0 0.9417369745164336 2 P40763 1
Interleukin receptor shc signaling 0.7325373134328386 0.4061704608792555 0.6846173566604428 1.0 0.9417369745164336 2 O15357 1
Erythropoietin activates ras 0.7325373134328386 0.4061704608792555 0.6846173566604428 1.0 0.9417369745164336 2 P46109 1
Signaling by fgfr4 in disease 0.7325373134328386 0.4061704608792555 0.6846173566604428 1.0 0.9417369745164336 2 P19174 1
Grb2 sos provides linkage to mapk signaling for integrins 0.7325373134328385 0.4061704608792543 0.6846173566604437 1.0 0.9417369745164336 2 Q9Y490 1
Signaling by tgfb family members 0.3259177837169412 0.4054682557585204 0.6851333477569619 1.0 0.9417369745164336 23 O14980,Q7Z3T8,P61081,O75909,Q93008,Q9Y5K5,P28482,Q8TEW0,Q9UPN9,P22681 10
Hdl clearance 0.7319402985074672 0.4046655697359554 0.6857233537266558 1.0 0.9417369745164336 2 Q8WTV0 1
Tnfr1 induced nfkappab signaling pathway 0.3281065558263944 0.395255606000748 0.6926542588346807 1.0 0.9451091431814742 9 Q12933,Q6GQQ9,P98170,O43318,Q13546,O15111 6
Gpvi mediated activation cascade 0.3957781537580441 0.3940646240803109 0.6935333280900027 1.0 0.9451091431814742 5 Q06124 1
Platelet aggregation plug formation 0.4183558282947198 0.3876940691865091 0.6982424452886895 1.0 0.9487360693560885 4 Q9Y490,P41240 2
Integrin signaling 0.4183558282947198 0.3876940691865091 0.6982424452886895 1.0 0.9487360693560885 4 Q9Y490,P41240 2
Recycling pathway of l1 0.3217246563195954 0.3862985319682986 0.6992755876083883 1.0 0.9492119792731052 23 O94973,P68371,P50570,Q9BVA1,O95239,P04350,Q00610,Q9BUF5,P26038,Q13885,P35241,P28482,Q15418,P15311 14
Synthesis of pips at the golgi membrane 0.3240558877504677 0.3790837031056302 0.704625707780099 1.0 0.9518267578370628 9 Q08AM6 1
Phenylalanine and tyrosine metabolism 0.3910965043322421 0.3779404062413246 0.7054748649279781 1.0 0.9520486041261064 5 P09417,P61457,P16930,Q7L266 4
Death receptor signalling 0.3139736755242464 0.377006855917087 0.7061685099374184 1.0 0.9520603577235806 30 Q14790,Q96BN8,Q9H8V3,O43318,Q14155,Q13501,P49327,P42574,O15111 9
Sting mediated induction of host immune responses 0.3523532233142765 0.375379114638552 0.7073785352835769 1.0 0.952767600817996 7 P19474 1
Signaling by tgf beta receptor complex 0.3162964512632463 0.3619216544220508 0.7174105774706572 1.0 0.9634789397915106 21 O14980,P61081,O75909,Q93008,Q9Y5K5,P28482,Q8TEW0,Q9UPN9,P22681 9
Interferon gamma signaling 0.3086191807180783 0.3563376786156458 0.7215876952816975 1.0 0.9656994547525032 13 P19474,P29372,Q14258 3
Signaling by fgfr 0.3148338323938365 0.3554065662576797 0.7222850303937696 1.0 0.9656994547525032 22 P19174,P35269,Q06124,P22681 4
Signaling by fgfr2 0.3148338323938365 0.3554065662576797 0.7222850303937696 1.0 0.9656994547525032 22 P19174,P35269,Q06124,P22681 4
Regulation of cholesterol biosynthesis by srebp srebf 0.3120852912947247 0.3527137827480677 0.7243030255064611 1.0 0.9656994547525032 27 O95486,Q9HCL2,P53992,Q15126,O95487,Q9Y6B6,Q15436,P62826,Q13907,P04035,Q01581,P48449,P49327,Q15648,Q86X55,P53602,O95749 17
Synthesis of pips at the er membrane 0.40738831662753 0.3523338074866133 0.7245879369131414 1.0 0.9656994547525032 4 P42356 1
Protein methylation 0.3459764082360731 0.3522884289936123 0.7246219649689647 1.0 0.9656994547525032 7 O60678,P13639 2
Senescence associated secretory phenotype sasp 0.3104410758215297 0.3372915791681347 0.7358971070226654 1.0 0.9731722785146052 21 P42771,Q00534,P20248,P28482,P40763,Q16763 6
Nf kb is activated and signals survival 0.7032835820895564 0.3357387741112909 0.7370678637739247 1.0 0.9731722785146052 2 Q13501 1
P75ntr signals via nf kb 0.7032835820895564 0.3357387741112909 0.7370678637739247 1.0 0.9731722785146052 2 Q13501 1
Interleukin 1 processing 0.703283582089556 0.3357387741112904 0.7370678637739252 1.0 0.9731722785146052 2 Q00653 1
Signaling by notch3 0.3409177912388668 0.3344841472179642 0.7380142514160521 1.0 0.9731722785146052 7 P67809 1
Abortive elongation of hiv 1 transcript in the absence of tat 0.304169844453122 0.3332348398995325 0.7389570211236551 1.0 0.9731722785146052 14 P18615,P35269 2
Endosomal sorting complex required for transport escrt 0.3262559808612328 0.3328077550844091 0.7392794039277633 1.0 0.9731722785146052 8 Q8WUX9,Q9H9H4,Q99816,O75351,Q9UN37,Q92783,Q9NZZ3 7
Regulated necrosis 0.3086256891230531 0.3327395636965684 0.739330882094549 1.0 0.9731722785146052 19 P49327,P41440,P09429,Q14790 4
Synthesis of pyrophosphates in the cytosol 0.6994029850746337 0.3269243170271285 0.7437251284632562 1.0 0.975352148226435 2 Q13572 1
Downregulation of tgf beta receptor signaling 0.352508571708502 0.3261869710798545 0.7442828983645862 1.0 0.975352148226435 6 O14980,Q9Y5K5 2
Fcgr3a mediated il10 synthesis 0.3377215481162315 0.3234767014592216 0.7463342494325467 1.0 0.9767997841272152 7 P17612,P19174 2
Pyroptosis 0.3740373751444173 0.3219178255061535 0.7475149486419801 1.0 0.9767997841272152 5 P09429 1
Sema3a pak dependent axon repulsion 0.3227570809363942 0.3204307082875769 0.7486418498851228 1.0 0.9767997841272152 8 P07900,Q16512,P08238,Q13153 4
Heme signaling 0.3459628267332579 0.3047516922038197 0.760555276359371 1.0 0.9869096062689734 6 Q96EB6,Q15648,O14980 3
Tbc rabgaps 0.2888353167194021 0.3005192260223375 0.7637811335276579 1.0 0.9869096062689734 10 Q9UJY4 1
Trif mediated programmed cell death 0.686865671641798 0.2993372300938526 0.7646827505807015 1.0 0.9869096062689734 2 Q14790 1
Tlr3 mediated ticam1 dependent programmed cell death 0.686865671641798 0.2993372300938526 0.7646827505807015 1.0 0.9869096062689734 2 Q14790 1
Semaphorin interactions 0.2997153269921973 0.2972703116696246 0.7662601455448357 1.0 0.9869871711072786 26 O75116,Q9BPU6 2
Rhobtb3 atpase cycle 0.4832066488090233 0.2957086893996692 0.7674525606376768 1.0 0.9869871711072786 3 O60664 1
Nr1h2 and nr1h3 mediated signaling 0.3623931822595102 0.2863171676830989 0.7746352103702061 1.0 0.9900305346585012 5 P49327 1
Dna damage recognition in gg ner 0.289815137795832 0.2753524833265462 0.783045446311913 1.0 0.995821747825763 15 Q16531,Q9UGN5,Q13619,Q92905,Q99627,Q13620,P09874,P61201,Q7L5N1,P54727 10
Deadenylation of mrna 0.2908956316184272 0.2714447228485567 0.786049008867578 1.0 0.996905221100304 17 O95628,P06730,Q9UIV1,Q5TAX3,Q04637,Q14240,A5YKK6 7
Oas antiviral response 0.4712498903908045 0.2672914754824303 0.78924474965872 1.0 0.9990230620178584 3 P61221 1
Metabolism of ingested semet sec mesec into h2se 0.6704477611940343 0.2653320174684166 0.7907537017597797 1.0 0.9992251322237216 2 P23526 1
Ca2 pathway 0.2907137659358972 0.2596590124696589 0.7951268116903705 1.0 1.0 9 Q08209 1
Metabolism of water soluble vitamins and cofactors 0.2603626755912531 0.2497856609618473 0.8027531092184439 1.0 1.0 42 P41440,Q99707,O96007,P00374,Q9NVE7,P49327,P78417,P43490 8
Hiv elongation arrest and recovery 0.2868557870136155 0.2472859870831376 0.8046869027807544 1.0 1.0 22 Q15369,P18615,Q8IXH7,P35269,O75909,Q9Y5B9 6
Conversion from apc c cdc20 to apc c cdh1 in late anaphase 0.2989892739672595 0.2433468156202858 0.8077367405046192 1.0 1.0 8 Q9UJX4,Q16763,Q9UJX5 3
Cytosolic sulfonation of small molecules 0.3682451459431387 0.2405852253230138 0.8098766023722594 1.0 1.0 4 Q96IU4,O95861 2
Rhobtb1 gtpase cycle 0.2840508736507768 0.2404772602247632 0.8099602898215967 1.0 1.0 20 O75116,Q5VTR2,O43396 3
Rip mediated nfkb activation via zbp1 0.3083285759725694 0.2317218024532799 0.816754096320822 1.0 1.0 7 Q00653,Q04206,O15111 3
Rhob gtpase cycle 0.281081299589154 0.2291963149528848 0.8187163366006003 1.0 1.0 21 P41440,Q9H8V3,O75116,Q16512,Q92974,Q16513 6
Transcriptional regulation by tp53 0.2734541949304503 0.22477636560018 0.8221532531356259 1.0 1.0 138 P31946,O75880,Q00535,Q15369,Q5RI15,Q8IXH7,Q16539,P42771,Q92696,P18074,Q9UER7,Q92547,O96017,Q9UQ84,P11413,P35244,P27348,O60921,Q15382,P67870,Q99873,P19784,O14965,Q92759,P31751,P24386,P55212,Q9UIV1,P20248,P30307,P49327,Q9HCE1,P14854,Q13535,O95628,P30154,P18615,P35269,O14744,P14635 40
Srp dependent cotranslational protein targeting to membrane 0.2299646318270783 0.2201031199486508 0.8257908450234541 1.0 1.0 93 P46776,P84098,P62750,P62861,P60866,P62917,P62906,P61254,P61247,P50914,P46778,O76094,P62081,Q9UHB9,P32969,P62701,P27635,P62847,P08708,P62854,P42766,P39019,P62269,P61513,P47914,P83731,P05387,P62753,P18621,P60059,P62899,P15880,P39023,P62266,P46783,P62841 36
Activation of gene expression by srebf srebp 0.2776172445938915 0.2198899886766432 0.8259568333858713 1.0 1.0 20 Q15126,P48449,P49327,Q15648,P53602 5
Deadenylation dependent mrna decay 0.2580633967985964 0.2169776559319785 0.8282257581202404 1.0 1.0 40 Q9Y2L1,O95628,Q6P2E9,Q14240,Q96C86,P26196,P06730,Q9Y450,Q5TAX3,Q92600,Q9UIV1,Q15477,Q04637,Q969T7,Q86TB9,Q96F86,A5YKK6 17
Trna processing 0.2026494711972315 0.2163522401324261 0.8287131914344859 1.0 1.0 67 Q9UJA5,O15091,O75818,Q2VPK5,Q7Z4G4,P57081 6
Tp53 regulates transcription of dna repair genes 0.268387223111649 0.2162528476515885 0.8287906615082665 1.0 1.0 35 Q15369,Q92759,P18615,P35269,P18074,Q13535 6
Metabolism of vitamins and cofactors 0.2198341050102076 0.2123014837799117 0.8318718379266605 1.0 1.0 51 P41440,Q99707,O96007,P00374,Q9NVE7,P49327,P78417,P43490 8
Met promotes cell motility 0.3103028203506939 0.2020559300326122 0.8398729999473469 1.0 1.0 6 P46109,Q96N67 2
Triglyceride catabolism 0.3055009150029657 0.1901684423142222 0.8491771392341478 1.0 1.0 6 P17612,Q8WTS1,O60664 3
Developmental biology 0.3603967491545096 0.1882824026646919 0.8506552792941937 1.0 1.0 270 O00560,P84098,Q03164,P62861,Q00535,Q15369,P62333,P61254,P61247,P60953,Q7Z460,P52564,P50914,P62906,P46778,P36578,Q9BUF5,O75116,P25787,Q86X55,O00487,Q9BPU6,P27635,P28066,P62847,P11802,Q96S59,P62241,Q00169,Q15648,Q13617,Q96EK7,P28070,P61160,O00231,P31751,O00330,Q14155,Q96P70,P18621,P50570,Q9BVA1,Q9NPJ6,O94973,P46776,O60271,Q13177,P68400,Q02750,Q02543,P25786,Q92796,P62829,P20618,Q16512,O15020,O00401,P32969,P62701,P62495,Q14997,P08708,P55036,P42766,P67870,Q9UNM6,P39019,Q9ULK4,Q9NR12,P11940,P48556,P28072,P25788,P15170,P51665,P07384,P04035,O15145,P05387,Q15418,P62899,P15880,Q14195,P62851,P62280,P39023,P62266,P46783,Q13885,P62841,P62195,P62191,Q16539,O14818,O43242,P62854,P61289,P62269,P35241,P61513,P40763,P49721,P19784,P47914,P35579,Q15334,Q14185,Q06124,Q04637,Q9Y490,Q13153,P07900,Q9Y2X0,P28074,P07737,P15311,P68371,P62993,P62750,P60866,P62917,P43686,P60900,P25789,Q15008,Q92600,P62081,P19174,P36507,P49720,P08238,O75832,Q9HAU5,Q13464,P83731,P04350,P62753,P28482,Q04206,Q00610,P35080,P17612,O95239,Q13200 144
Eph ephrin signaling 0.2624705494150632 0.1826157826792096 0.8550994998027803 1.0 1.0 32 O75116,Q14155 2
Assembly of the hiv virion 0.6232835820895579 0.1817255388220909 0.8557981225986069 1.0 1.0 2 Q9H9H4 1
Phenylalanine metabolism 0.4269931322782969 0.1775463602639564 0.85907925338836 1.0 1.0 3 P61457,Q7L266 2
Atf4 activates genes in response to endoplasmic reticulum stress 0.2521855692649848 0.1770671994198806 0.8594556058579601 1.0 1.0 12 Q9Y2L1 1
Ikk complex recruitment mediated by rip1 0.3180231250912053 0.172704276225138 0.8628838823623914 1.0 1.0 5 O15111 1
Cdc42 gtpase cycle 0.2566751638513901 0.172520694072896 0.8630281937493587 1.0 1.0 34 Q16512,Q96N67,Q14155,Q9UQB8 4
Enos activation 0.3357228195937758 0.1670244394259635 0.8673508191518069 1.0 1.0 4 P07900,O75608,O95865 3
Signaling by fgfr2 in disease 0.245784174372703 0.1663929960469408 0.867847685468591 1.0 1.0 11 P62993,P19174,P35269 3
Sumoylation of immune response proteins 0.4197357840824406 0.1652380754429367 0.8687565972841005 1.0 1.0 3 Q00653 1
Mitophagy 0.246317237415431 0.1589298790347795 0.8737241198095422 1.0 1.0 13 P67870,P19784 2
Golgi associated vesicle biogenesis 0.2558384773590404 0.1588087838802881 0.8738195281071623 1.0 1.0 30 O43747,O60749,P50570,P54920,Q14677,O00203,Q14789,Q9BXS5,Q9Y5X3,Q10567,Q00610,Q8NC96,Q01968,O00443,P49407 15
Mitotic metaphase and anaphase 0.2601970713436886 0.157319139459665 0.8749933369666556 1.0 1.0 141 P68371,P62191,P63151,P43686,P60900,P53350,Q7Z460,Q9HBM1,P25789,Q15008,O95067,Q9BUF5,P25786,Q6P1K2,P25787,P50748,P20618,O00487,Q9Y6G9,Q14008,O60566,O14818,O14980,O43242,P28066,Q14997,O43684,P55036,P49720,P61289,O75832,P28070,P49721,Q99661,Q2NKX8,O43683,Q9H900,Q92973,Q9P258,Q8IXJ6,P04350,Q9UJX4,Q92674,O43237,Q29RF7,Q7Z5K2,P43034,Q99986,P30154,Q14738,P14635,P28074,O43264,Q13885,Q16763,Q14204,Q15691,P62195,Q13200 59
Ticam1 rip1 mediated ikk complex recruitment 0.3294448489119783 0.1549704641149971 0.8768446021896559 1.0 1.0 4 O15111 1
Transcriptional regulation by ventx 0.2432270559100879 0.1484337274681971 0.8820004842073512 1.0 1.0 14 Q04206,Q9UJX5,P42771,Q9UJX4,Q9HCE1,Q16763 6
Metabolism of steroids 0.2122686025245076 0.147801233748172 0.8824996356433965 1.0 1.0 49 Q15392,Q9BWD1,Q9HCL2,Q15126,Q9Y6B6,P22059,Q9BZF3,P48449,P49327,Q15648,P53602 11
Hdr through mmej alt nhej 0.2604665071770335 0.1467485521689741 0.8833304943295373 1.0 1.0 8 Q9UGN5,P49916,P18887,O60934,P09874,P39748,Q92878 7
Rho gtpases activate ktn1 0.2589712918660227 0.1437375823692686 0.885707692899016 1.0 1.0 8 P84095,P61586,P60953,Q07866,Q9H0B6,P33176,P63000 7
Constitutive signaling by aberrant pi3k in cancer 0.282189840728653 0.139358639945982 0.8891667539160402 1.0 1.0 6 P62993,Q06124 2
Formation of tc ner pre incision complex 0.2485088075486597 0.1382226704011851 0.8900644386773915 1.0 1.0 25 Q13619,Q7L5N1,Q92905,Q92759,P18074,P61201,Q99627 7
Nef mediated downregulation of mhc class i complex cell surface expression 0.3003430412203577 0.1378453226619529 0.8903626639344053 1.0 1.0 5 Q10567,Q9BXS5 2
Cholesterol biosynthesis 0.2447869551540906 0.1378024689477487 0.8903965330398367 1.0 1.0 19 Q9BWD1,Q15392,P48449,Q15126 4
Met activates ptpn11 0.4013896487935557 0.1371806854086353 0.8908879773803089 1.0 1.0 3 Q06124 1
Rhobtb gtpase cycle 0.2450495683905058 0.1327119370429777 0.894421201981445 1.0 1.0 30 Q8IYB3,Q99832,Q13464,Q8N684,P07900,Q13618,P78371,Q16543,P40227,Q96DH6,P08238,Q5VTR2,P61201,O75116,Q9UM54,P12814,O43396 17
Metabolism of folate and pterines 0.239331414437945 0.1307571863366083 0.8959673924800979 1.0 1.0 9 P41440 1
Butyrate response factor 1 brf1 binds and destabilizes mrna 0.227674204139608 0.129124134963418 0.8972594249329542 1.0 1.0 11 Q9Y2L1 1
Rac1 gtpase cycle 0.2105435399552512 0.1218922832184021 0.9029843271555742 1.0 1.0 47 Q96N67,Q9UQB8,Q9H8V3,Q14185,Q14155,Q16512 6
Formation of rna pol ii elongation complex 0.2385984095594475 0.1216552398631145 0.9031720632603376 1.0 1.0 32 Q15369,Q92759,P18615,P35269,P18074 5
Clathrin mediated endocytosis 0.1932961850468114 0.1212169556124589 0.903519194510348 1.0 1.0 52 P62993,O00401,Q8N6T3,Q7L5N1,P50570,Q92905,Q96D71,P20645,Q8NC96,P49407,Q00610,P61201,Q01968,Q9NVZ3,Q14C86,O00443,Q99627,P22681 18
Rab regulation of trafficking 0.2366067687129872 0.1175978643149013 0.906386297234699 1.0 1.0 32 Q7Z392,P31751,P24386,Q9UJY4,Q8TC07,Q15042 6
Post translational protein modification 0.19436553216623 0.1158114715643619 0.9078019587018766 1.0 1.0 405 Q15369,P85037,Q9BUF5,P51784,P25787,O95394,P47755,O00487,Q14999,O60725,Q9Y6B6,P28066,P49427,Q96RU2,Q86VP6,Q13617,P28070,Q99627,O15084,Q9UPT9,Q5TAQ9,P61086,P24386,O60678,P13639,P14735,O95487,P24390,P53618,P26572,P48444,Q96BN8,Q93008,Q14204,Q14527,P34949,Q9Y3I1,Q9UER7,Q9UBF2,P25786,P22314,P20618,O43505,O15020,O00743,Q14997,P61923,Q06210,P61081,P55036,P26358,P45974,P40818,Q5H9R7,Q96JB2,O43237,Q9UIS9,Q16186,P15880,Q9BV10,Q92734,O94966,O75935,A0AVT1,Q13885,P62195,Q16763,P47756,P62191,Q8N6T3,Q96K76,Q93034,P42771,Q14694,Q92696,Q14258,O60826,Q14166,Q13619,O14818,Q9NR45,O15027,Q9UBT2,P68036,Q04323,O43242,O43318,P61289,P61962,P49721,P49407,Q8TBC4,Q13618,Q6GQQ9,P20248,O60493,Q13564,Q86UV5,Q92538,Q9NZ32,Q92905,Q9BQC3,Q5VTR2,P28074,O95630,P60900,Q15008,Q96IJ6,Q13309,Q00653,P49720,Q96FW1,Q9Y5A7,O14965,P04350,P63241,P61201,Q15293,Q7L5N1,Q14746,P53602,Q13200 122
Fbxw7 mutants and notch1 in cancer 0.5680597014925446 0.1109810134507633 0.9116314027841672 1.0 1.0 2 Q13616 1
Sensory processing of sound 0.2280385380595017 0.1098497721052761 0.9125285174260572 1.0 1.0 18 P47756,P35579,Q6IBS0,P35241,P15311,P47755 6
Regulation of pten localization 0.5665671641791117 0.1094630893345811 0.9128351962481092 1.0 1.0 2 Q93009 1
Translocation of slc2a4 glut4 to the plasma membrane 0.2223622707102954 0.1094006211712307 0.9128847410833614 1.0 1.0 40 P35579,P31946,P27348,P63104,O60343,Q86X10,P31751,P04350,Q96KP1,Q8TAG9,Q9BUF5,Q13885 12
Dex h box helicases activate type i ifn and inflammatory cytokines production 0.2999017669497051 0.1075690528306528 0.9143375467739356 1.0 1.0 4 Q00653 1
Perk regulates gene expression 0.2200668991263252 0.1072189742219003 0.9146152629467176 1.0 1.0 14 Q9Y2L1 1
Infectious disease 0.1992528314520046 0.1051816829032868 0.9162316450174262 1.0 1.0 359 O00410,P84098,P62861,Q9UQB8,Q15369,P62906,P62333,P61254,Q8IXH7,P61247,P60953,P52564,Q99570,P50914,P46778,Q9BUF5,P36578,O75116,P25787,Q13546,O00487,P62847,P27635,P28066,O60942,Q96SB4,P28070,P18858,P78362,P13639,P18621,P26572,P45985,P35269,Q14204,P46776,O00629,Q9BXS5,Q9UER7,P25786,P20618,P22681,O00401,P32969,P62701,Q14997,P08708,P55036,P42766,P39748,P39019,Q92759,P05387,O43237,P62899,P15880,P43487,P18615,P39023,P62266,P46783,Q13885,P62841,P62195,P62191,Q93034,Q16539,P18074,Q9NZQ3,O14818,O14980,O43242,P62854,P61289,P12268,P62269,P61513,P49721,P47914,P35579,Q13618,Q14185,Q9Y5B9,P07900,O75909,O75351,P28074,P68371,P29083,P60866,P62993,P62750,P62917,P60900,P43686,P25789,Q15008,Q9Y6G9,Q00653,P62081,P19174,P36507,P49720,P13984,P08238,O75832,Q99873,Q13464,P83731,P04350,P07437,P20839,P62753,P28482,Q04206,Q9UHD2,Q9H9H4,Q00610,P17612,P13010,P00558,Q13200 122
Irf3 mediated induction of type i ifn 0.2603108188882182 0.1020908547325484 0.9186845599528252 1.0 1.0 6 Q9UJV9,Q9UHD2,P78527,P12956,P13010 5
Cellular responses to stimuli 0.2197219677858193 0.101025830328602 0.9195299554353278 1.0 1.0 341 P84098,P62861,P36543,Q15369,P62906,P62333,P61254,P61247,P52564,P50914,P46778,Q9BUF5,P36578,Q92598,P25787,Q86X55,P47755,O00487,Q14999,Q13616,Q9H1A4,P35244,P62847,P27635,P28066,P11802,P62241,Q15382,P27694,Q15648,Q13617,P28070,P14854,P18621,Q13535,Q96B36,P51858,P45985,P30519,Q14204,P46776,O75880,Q9Y5K8,P25786,P20618,P32969,P35611,P62701,Q14997,P08708,Q06210,P55036,P42766,P39019,P67870,Q9UL15,Q9UJX4,P05387,O43237,Q9HCE1,P62899,P15880,Q9Y2L1,P05198,O75935,P39023,Q00534,P62266,P46783,Q13885,P62841,P62195,Q16763,P47756,P62191,Q8N6T3,Q5RI15,Q16539,P42771,Q99615,O14818,O14980,O43242,P62854,P61289,P08243,P62269,P31689,P61513,P40763,P49721,P19784,Q96EB6,P47914,Q13618,Q14203,P20248,Q9Y490,Q92616,Q9NZ32,P07900,Q9GZT9,P28074,O75182,P68371,P60866,P62750,P62917,P60900,P43686,P53004,P25789,Q15008,Q13309,Q9Y6G9,P62081,P49720,P08238,O75832,P30043,Q13555,P83731,P04350,P62753,P28482,Q04206,Q9UJX5,O60884,O95070,Q0VDF9,O94979,Q13200 132
Rna polymerase ii transcription 0.184803392744152 0.0994096750989963 0.9208130011987188 1.0 1.0 334 Q03164,Q00535,Q15369,Q8IXH7,P25787,Q9UQ84,O00487,P35244,P28066,P11802,O60921,O60942,Q15382,Q92620,Q15648,P28070,Q9HCL2,P31751,P24386,P55212,P14854,Q13535,Q9H814,P30154,P35269,Q93008,O75880,Q9UER7,P25786,P20618,O96017,P31350,Q05519,Q14997,P55036,P67870,Q8IYB3,Q92759,Q9UJX4,Q9UIV1,Q9HCE1,O95628,P18615,P42858,Q00534,P62195,Q16763,P62191,Q6P9B9,Q5RI15,Q16539,P42771,Q92696,P18074,Q96P16,Q96HW7,Q14353,Q9UPN9,P27348,P63104,O14818,O43242,P61289,P49721,P19784,Q96EB6,P20248,P49327,Q06124,Q9Y2X0,P28074,P14635,O75182,P29083,P31946,P60900,Q15008,Q6PL18,Q92547,Q13309,P11413,P49720,Q99873,P10589,O14965,P30307,P51003,P28482,O14744,Q13200 90
Sensory processing of sound by outer hair cells of the cochlea 0.2109215089706481 0.0974428726562621 0.922374699245142 1.0 1.0 13 P35241,Q6IBS0,P35579,P15311 4
Cell cycle 0.2840756041680228 0.0952827935020111 0.9240902092639344 1.0 1.0 313 Q7Z460,P25205,Q9BT25,Q9BUF5,Q6P1K2,P25787,P50748,Q9UQ84,O00487,P35244,O60566,Q9UH99,P28066,P11802,O60921,Q96CW5,P28070,P18858,O15084,Q99661,Q01105,Q9UBD5,Q9H900,Q9P258,Q9Y570,P31751,P04183,Q13535,P43034,P30154,Q14204,Q9BRT9,Q9BPX3,Q9HBM1,Q9BUR4,O95067,Q9UER7,P25786,P20618,O96017,P49005,P31350,O00743,Q99996,Q14997,P55036,P39748,P67870,Q2NKX8,P28340,Q5H9R7,Q7Z4H7,Q9BSJ2,Q9UJX4,Q9NTJ3,O43237,Q9UIS9,Q9HC35,O75935,Q07864,Q00534,Q15021,Q15003,Q13885,Q15691,P62195,Q16763,P62191,P41440,P42771,Q14008,P27348,P63104,O14818,O14980,O43242,O43684,P61289,P49642,P49721,P19784,Q92973,Q8IXJ6,Q14203,P00374,P20248,Q7Z5K2,Q99986,P07900,O95347,P28074,O43264,P14635,P68371,P31946,P63151,P49643,P60900,P43686,P35251,P53350,P42695,P25789,Q15008,Q92547,Q13309,P49720,O14965,P04350,P07437,P30307,P28482,Q6IBW4,Q14738,Q13200 115
Cell cycle mitotic 0.3009063288538984 0.0943476058372886 0.924833034549872 1.0 1.0 262 Q7Z460,P25205,Q9BT25,Q9BUF5,Q6P1K2,P25787,P50748,O00487,O60566,P35244,P28066,P11802,Q96CW5,P28070,P18858,Q99661,Q01105,Q9UBD5,Q9H900,Q9P258,Q9Y570,P31751,P04183,P43034,P30154,Q14204,Q9BRT9,Q9BPX3,Q9HBM1,O95067,P25786,P20618,P49005,P31350,Q99996,Q14997,P55036,P39748,P67870,Q2NKX8,P28340,Q7Z4H7,Q9BSJ2,Q9UJX4,Q9NTJ3,O43237,Q9UIS9,Q9HC35,O75935,Q07864,Q00534,Q15021,Q15003,Q13885,Q15691,P62195,Q16763,P62191,P41440,P42771,Q14008,O14818,O14980,O43242,O43684,P61289,P49642,P49721,P19784,Q92973,Q8IXJ6,Q14203,P00374,P20248,Q7Z5K2,Q99986,P07900,O95347,P28074,O43264,P14635,P68371,P63151,P49643,P43686,P35251,P60900,P53350,P25789,P42695,Q15008,Q13309,P49720,O14965,P04350,P07437,P30307,P28482,Q6IBW4,Q14738,Q13200 101
Ovarian tumor domain proteases 0.1984921563622755 0.0906896255320029 0.9277392142864852 1.0 1.0 10 Q14258 1
Innate immune system 0.2275952770729782 0.0897327924759806 0.9284995564214162 1.0 1.0 292 O00560,P36543,Q9UQB8,P62333,P60953,Q7Z6Z7,P52564,P61020,P50395,Q99570,P46940,Q9NW08,P25787,Q13546,P47755,Q7L576,O00487,O75874,P09972,P14618,P28066,P49427,Q86VP6,P28070,P61086,P13639,O95352,P46976,P53618,P50570,P45985,P30519,P30154,Q14204,Q9NQR4,Q9Y5K8,Q9BXS5,P25786,P22392,P20618,Q16512,O15111,O00401,P04075,Q9Y487,Q14997,P61081,P55036,P67870,Q08209,Q8IV63,Q14790,Q99439,P07741,P00491,O60610,O15160,P63172,P62195,P62191,Q5T4S7,Q16539,Q14258,Q9NZQ3,Q9Y376,Q9BUI4,O14818,O43242,P17858,O43318,P12268,P61289,O75165,P09429,P51452,P19474,P49721,P35579,Q8TBC4,Q14185,Q06124,Q9UNP9,Q9NZ32,Q13153,P07900,P04080,P28074,O00764,P18669,P68371,P62993,P43686,P60900,P25789,Q15008,Q93050,Q9Y6G9,Q00653,O14802,P09960,P19174,P49720,P53396,P08238,O75832,Q9UII4,Q13526,Q13464,P36871,P07437,P20839,P28482,Q8IUR7,Q5T9A4,Q04206,Q9UQ80,Q9UHD2,Q14738,P06737,P17612,P13010,Q13200 122
Tristetraprolin ttp zfp36 binds and destabilizes mrna 0.1991772321982873 0.0865525355419799 0.9310271953949544 1.0 1.0 12 Q9Y2L1 1
Platelet homeostasis 0.1975030947745898 0.0848898469113362 0.9323489636414686 1.0 1.0 12 P30154,Q06124,Q14738 3
Leishmania infection 0.2033772276411598 0.0846302560546285 0.9325553444969632 1.0 1.0 43 Q00653,P62993,O00401,P35579,Q04206,Q9UQB8,P19174,P60953,Q16539,Q14185,P08238,P17612,P28482,Q9NZQ3,Q7L576 15
Signal regulatory protein family interactions 0.3534208995796356 0.0836793253588823 0.9333113954561952 1.0 1.0 3 Q06124 1
Signaling by notch1 0.1912083089447933 0.0834015995670805 0.933532216674288 1.0 1.0 10 Q04727,P49407 2
M phase 0.2582896581693213 0.0800359449612126 0.9362086677126352 1.0 1.0 199 P68371,P62191,P63151,P43686,P60900,P53350,Q7Z460,Q9HBM1,P25789,Q15008,P42695,O95067,Q9BT25,Q9BUF5,P25786,Q6P1K2,P25787,P50748,P20618,O00487,Q14008,Q99996,O60566,O14818,O14980,O43242,P28066,Q14997,O43684,P55036,P49720,Q96CW5,P61289,P67870,P28070,P49721,Q99661,Q2NKX8,Q01105,P19784,Q9H900,Q92973,Q9P258,Q7Z4H7,Q8IXJ6,P04350,Q9BSJ2,Q9UJX4,Q14203,P07437,Q9NTJ3,O43237,P28482,Q9UIS9,Q7Z5K2,Q6IBW4,Q9HC35,P43034,O75935,Q99986,P30154,P07900,O95347,Q14738,P14635,Q15021,Q15003,Q13885,Q16763,Q14204,P28074,Q15691,P62195,O43264,Q9BPX3,Q13200 76
Vesicle mediated transport 0.2097053373101217 0.0793733183208324 0.9367356905645708 1.0 1.0 247 P53992,Q7Z392,P61020,Q96KP1,P50395,Q9BUF5,P20645,P47755,O60333,Q9Y6B6,Q99627,Q99661,O15084,P31751,P24386,O95487,P24390,P53618,Q5VZE5,P48444,P50570,P43034,Q8TAG9,Q8TD16,Q9UJY4,Q14204,Q14C86,Q15042,Q9UID3,Q9H0B6,Q9BXS5,Q9UBF2,Q96Q89,P22681,O00743,O15020,O00401,P61923,Q5H9R7,Q86X10,Q96JB2,O43237,Q92734,O75935,O00203,Q13885,Q8TC07,P52732,P47756,Q8N6T3,Q9NVZ3,Q8WTV0,P27348,P63104,O15027,P33176,P49407,P35579,Q14203,Q92538,Q9NZ32,Q92905,P07900,Q9Y5X3,O75351,O43264,O60664,Q01968,P54920,P68371,P62993,P31946,P53621,Q8NC96,Q9Y6G9,O60343,Q15436,Q9Y3P9,Q14789,Q96D71,O00443,P04350,P61201,Q7L5N1,Q9NVG8,Q14746,Q9H9H4,Q00610,O95239,P35606,O94979,Q14677 92
Cytokine signaling in immune system 0.2505612476233455 0.0787288804059866 0.9372482735286364 1.0 1.0 185 P62191,P62993,O00629,O00170,Q15369,P43686,P61221,P60900,P25789,Q93034,Q9Y3Z3,Q16539,P41240,Q15008,Q14258,P25786,Q6L8Q7,P78417,P20618,P25787,O00487,O15111,P22681,Q00653,P63104,O14818,O15344,O43242,P28066,Q14997,P61081,Q13126,P55036,O43318,P61289,P19174,Q00169,P09429,P51452,O43432,P19474,P29372,O75832,P40763,P28070,P49721,Q8IV63,P78344,Q9UII4,Q13555,Q8TBC4,Q99439,O15357,P31751,Q06124,Q04637,P28482,Q14240,P17987,Q9H3K6,P45985,P07900,P30154,P06730,Q9UHD2,Q14738,P46109,P28074,O60573,Q13501,P42574,P49720,P62195,Q13200 74
Downregulation of smad2 3 smad4 transcriptional activity 0.25786774566054 0.0781964162736267 0.937671812689872 1.0 1.0 5 Q93008,Q9UPN9 2
Membrane trafficking 0.2186348026906331 0.0778285115969669 0.9379644662565794 1.0 1.0 240 P53992,Q7Z392,P61020,Q96KP1,Q9BUF5,P20645,P47755,O60333,Q9Y6B6,Q99627,Q99661,O15084,P31751,P24386,O95487,P24390,P53618,Q5VZE5,P48444,P50570,P43034,Q8TAG9,Q8TD16,Q9UJY4,Q14204,Q14C86,Q15042,Q9UID3,Q9H0B6,Q9BXS5,Q9UBF2,Q96Q89,P22681,O00743,O15020,O00401,P61923,Q5H9R7,Q86X10,Q96JB2,O43237,Q92734,O75935,O00203,Q13885,Q8TC07,P52732,P47756,Q8N6T3,Q9NVZ3,P27348,P63104,O15027,P33176,P49407,P35579,Q14203,Q92538,Q9NZ32,Q92905,Q9Y5X3,O75351,O43264,O60664,Q01968,P54920,P68371,P62993,P31946,P53621,Q8NC96,Q9Y6G9,O60343,Q15436,Q9Y3P9,Q14789,Q96D71,O00443,P04350,P61201,Q7L5N1,Q9NVG8,Q14746,Q9H9H4,Q00610,O95239,P35606,O94979,Q14677 89
Met receptor recycling 0.3428744608799992 0.0754439901971592 0.9398614598004672 1.0 1.0 3 P46109 1
Translation 0.1899786295287887 0.0726877054401626 0.942054632305529 1.0 1.0 218 Q05639,P84098,P62861,P62906,P61254,P61247,P50914,P46778,P54136,P26639,P27635,P62847,P46199,Q7Z7F7,P13639,Q14240,P18621,P26640,Q9Y285,P49770,P46776,Q9P2J5,Q14232,O76094,P29692,P32969,P62701,P62495,P08708,P47897,P42766,P41252,P39019,Q96E11,Q96I59,Q13144,Q9Y262,P05387,P60059,P62899,P15880,P05198,P39023,P62266,P46783,P62841,Q15056,P62854,P07814,P62269,P61513,P54577,P47914,Q04637,Q9NR50,P06730,O75821,P26641,P62750,P60866,P62917,Q15181,Q14152,P62081,Q9UHB9,O60841,O15371,Q9NSD9,P83731,O43776,P55010,P49591,Q8TAE8,P62753,Q9H2U2,Q9HD33,P49589,P23381 78
Rho gtpases activate pkns 0.2014961914844483 0.0715158811238803 0.9429871856113072 1.0 1.0 24 P35579,P31946,P27348,P63104,P30307,Q16512,Q16513 7
P75ntr negatively regulates cell cycle via sc1 0.5194029850746352 0.0711479426764495 0.9432800120817968 1.0 1.0 2 Q13547 1
Asparagine n linked glycosylation 0.2066529945619742 0.0710961767597053 0.9433212109764976 1.0 1.0 123 P47756,P62191,P34949,P68371,P53621,Q8N6T3,Q9BUF5,Q9UBF2,Q96IJ6,Q16222,O95394,P47755,Q9Y6G9,O00743,O15020,Q9NR45,Q9Y6B6,O15027,P61923,Q04323,Q06210,Q15436,O15084,Q5H9R7,Q96JB2,P04350,Q14203,O43237,O95487,P24390,Q9UJ70,P53618,P26572,P48444,Q9BV10,Q92734,Q9NZ32,O75935,Q92538,Q14746,P53602,Q13885,Q14204,P54920 44
Mitochondrial trna aminoacylation 0.1912546920851219 0.0700006190584914 0.9441931669104208 1.0 1.0 18 P47897,P26640,Q9H2U2 3
Metabolism of amino acids and derivatives 0.2298940820219249 0.0695950540703218 0.944515973677224 1.0 1.0 192 P84098,P62861,P62906,P62333,P61254,P61247,P50914,P46778,P36578,P54136,P25787,O00487,P27635,P28066,P62847,Q13126,P62241,P28070,P23526,Q99707,O00231,P32929,O00330,P18621,P49419,P46776,Q9P2J5,O43252,P00390,Q02543,P25786,P62829,Q13155,P20618,P25325,P61457,P32969,P62701,Q14997,P08708,P55036,P47897,P42766,P41252,P39019,Q9UNM6,P48556,P28072,P25788,P14868,P51665,P05387,P62899,P15880,P62851,P62280,P39023,P62266,P46783,P62841,P62195,P62191,Q14353,Q9Y617,O14818,O43242,P62854,P07814,P61289,P08243,P62269,P61513,P49721,P47914,P28074,P62750,P60866,P62917,P43686,P60900,P25789,Q15008,P62081,P49720,O75832,P19623,P16930,P83731,P49591,P62753,P12277,Q13200 92
Cargo recognition for clathrin mediated endocytosis 0.2013534287487995 0.0684707839838709 0.9454108764825806 1.0 1.0 32 Q92905,Q96D71,P20645,P61201,Q7L5N1,P22681 6
Formyl peptide receptors bind formyl peptides and many other ligands 0.5137313432835906 0.0677004958827723 0.9460240545615056 1.0 1.0 2 Q9NRV9 1
Rho gtpases activate paks 0.173821948215 0.0661263279783857 0.947277250025078 1.0 1.0 13 P35579,P60953,Q13153,Q16512 4
Rna polymerase ii transcribes snrna genes 0.197946833923105 0.0656658568156511 0.9476438560328768 1.0 1.0 32 P29083,Q9H814,Q6P9B9,P35269,O75909,Q96P16,Q96HW7,Q9NV88 8
Intra golgi traffic 0.1713086674056755 0.0649215921378447 0.9482364288185332 1.0 1.0 13 Q96JB2 1
Selective autophagy 0.1931765012310614 0.0637159193415003 0.9491964287021172 1.0 1.0 38 P68371,P07900,P04350,Q9BUF5,Q13501,P67870,Q13885,Q14204,O43237,O60664,P19784 11
O linked glycosylation 0.2526881720430037 0.0611429105801755 0.951245395356539 1.0 1.0 4 O43505,Q10472,Q86SF2 3
O linked glycosylation of mucins 0.2526881720430035 0.0611429105801755 0.951245395356539 1.0 1.0 4 O43505,Q10472,Q86SF2 3
Disorders of transmembrane transporters 0.160657825849858 0.059799278396198 0.9523155003065468 1.0 1.0 73 P62191,P60900,O14818,Q13200,Q15008,P28066,Q14997,P55036,P49720,P20618,P61289,P28070,P28074,P25786,P25787,P62195,O00487,P49721 18
Hats acetylate histones 0.184530787545763 0.0589501599122849 0.9529918056546124 1.0 1.0 27 O14929,Q6IA86,Q9UPT9 3
Activation of ppargc1a pgc 1alpha by phosphorylation 0.2458183990441965 0.0569353294569884 0.9545967111099436 1.0 1.0 4 P54619,Q9Y478,Q16539 3
Organelle biogenesis and maintenance 0.1721046289492556 0.0560835231922924 0.955275269865452 1.0 1.0 95 P68371,Q7Z460,Q16539,Q96KP1,Q9BT25,Q9BUF5,Q3SYG4,Q14008,Q99996,P48735,Q15648,Q9BW83,P49368,Q92973,Q7Z4H7,P04350,Q14203,P07437,P17987,Q9UIS9,Q92538,P43034,O75935,P07900,Q8TAG9,Q13885,Q14204,Q15691,P48643 29
Trans golgi network vesicle budding 0.1829329749054123 0.0559609456122533 0.9553729192678364 1.0 1.0 36 Q92538,P50570,P54920,Q14677,O00203,Q14789,Q9BXS5,Q9Y5X3,P20645,Q8NC96,Q01968,O00443,P49407 13
Hiv infection 0.1806573494561362 0.0558678758334045 0.9554470622157476 1.0 1.0 138 P62191,P29083,P43686,Q15369,P60900,P25789,Q8IXH7,Q93034,Q15008,Q9BXS5,P18074,P25786,P20618,P25787,O00487,O14818,O14980,O43242,P28066,Q14997,P55036,P49720,P13984,P61289,O60942,P39748,P28070,P18858,P49721,Q92759,Q9Y5B9,P43487,P18615,P35269,O75909,O75351,P28074,P62195,Q13200 39
Rab gefs exchange gtp for gdp on rabs 0.1745113545214905 0.0549170665974994 0.9562045352179817 1.0 1.0 27 P31751 1
Copii mediated vesicle transport 0.1789069703869384 0.0543004080154059 0.9566958244853988 1.0 1.0 33 Q9Y6B6,O15084 2
Influenza infection 0.1753699591166974 0.0538522342154305 0.9570528929776112 1.0 1.0 127 O00410,P84098,P46776,P62861,O00629,P62750,P62906,P60866,P61254,P61247,P62917,P50914,P46778,P62081,P32969,O14980,P62701,P27635,P62847,P08708,P62854,P13984,P42766,P39019,P62269,P61513,P47914,P83731,P05387,P62753,P18621,P62899,P15880,P07900,P35269,P39023,P62266,P46783,Q00610,P62841 40
Antigen activates b cell receptor bcr leading to generation of second messengers 0.3018811585547855 0.0532822805296394 0.957506998233737 1.0 1.0 3 P62993,O43865 2
Formation of fibrin clot clotting cascade 0.2818751866228622 0.0470332475816943 0.9624867291024524 1.0 1.0 3 Q9UNN8,P42785 2
Host interactions of hiv factors 0.1471287617619493 0.0462079106662685 0.9631445374114294 1.0 1.0 95 P62191,P60900,Q15369,Q93034,Q15008,Q9BXS5,P25786,P20618,P25787,O00487,O14818,O14980,P28066,Q14997,P55036,P49720,P61289,P28070,P49721,P43487,P28074,P62195,Q13200 23
Activated notch1 transmits signal to the nucleus 0.2591818453269552 0.0425130623715349 0.9660896988984864 1.0 1.0 3 Q96J02,P49407 2