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  1. interpro_active_site/advanced/idx2term.json +1 -0
  2. interpro_active_site/basic/idx2term.json +1 -0
  3. interpro_active_site/basic/plot_0.png +3 -0
  4. interpro_active_site/consensus.joblib +3 -0
  5. interpro_active_site/df_merge.tsv +1 -0
  6. interpro_active_site/metrics.json +7 -0
  7. interpro_active_site/paths.json +1 -0
  8. interpro_active_site/result.tsv +11 -0
  9. interpro_active_site/selections.json +1 -0
  10. interpro_binding_site/advanced/idx2term.json +1 -0
  11. interpro_binding_site/advanced/plot_0.png +3 -0
  12. interpro_binding_site/basic/idx2term.json +1 -0
  13. interpro_binding_site/basic/plot_0.png +3 -0
  14. interpro_binding_site/basic/plot_1.png +3 -0
  15. interpro_binding_site/consensus.joblib +3 -0
  16. interpro_binding_site/df_merge.tsv +2 -0
  17. interpro_binding_site/metrics.json +7 -0
  18. interpro_binding_site/paths.json +1 -0
  19. interpro_binding_site/result.tsv +8 -0
  20. interpro_binding_site/selections.json +1 -0
  21. interpro_conserved_site/advanced/idx2term.json +1 -0
  22. interpro_conserved_site/advanced/plot_0.png +3 -0
  23. interpro_conserved_site/basic/idx2term.json +1 -0
  24. interpro_conserved_site/basic/plot_0.png +3 -0
  25. interpro_conserved_site/basic/plot_1.png +3 -0
  26. interpro_conserved_site/basic/plot_2.png +3 -0
  27. interpro_conserved_site/basic/plot_3.png +3 -0
  28. interpro_conserved_site/basic/plot_4.png +3 -0
  29. interpro_conserved_site/basic/plot_5.png +3 -0
  30. interpro_conserved_site/basic/plot_6.png +3 -0
  31. interpro_conserved_site/basic/plot_7.png +3 -0
  32. interpro_conserved_site/basic/plot_8.png +3 -0
  33. interpro_conserved_site/basic/plot_9.png +3 -0
  34. interpro_conserved_site/consensus.joblib +3 -0
  35. interpro_conserved_site/df_merge.tsv +2 -0
  36. interpro_conserved_site/metrics.json +7 -0
  37. interpro_conserved_site/paths.json +1 -0
  38. interpro_conserved_site/result.tsv +44 -0
  39. interpro_conserved_site/selections.json +1 -0
  40. interpro_domain/advanced/idx2term.json +1 -0
  41. interpro_domain/advanced/plot_0.png +3 -0
  42. interpro_domain/advanced/plot_1.png +3 -0
  43. interpro_domain/advanced/plot_2.png +3 -0
  44. interpro_domain/advanced/plot_3.png +3 -0
  45. interpro_domain/advanced/plot_4.png +3 -0
  46. interpro_domain/advanced/plot_5.png +3 -0
  47. interpro_domain/basic/idx2term.json +1 -0
  48. interpro_domain/basic/plot_0.png +3 -0
  49. interpro_domain/basic/plot_1.png +3 -0
  50. interpro_domain/basic/plot_10.png +3 -0
interpro_active_site/advanced/idx2term.json ADDED
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+ {}
interpro_active_site/basic/idx2term.json ADDED
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+ {"0": "Serine/threonine-protein kinase, active site [IPR008271]"}
interpro_active_site/basic/plot_0.png ADDED

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interpro_active_site/df_merge.tsv ADDED
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+ term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500
interpro_active_site/metrics.json ADDED
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+ {
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+ "type_of_task": "ranksum",
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+ "signature_size": 3353,
4
+ "annotations_size": 54,
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+ "title": "Average number of proteins per term",
6
+ "value": 2.962962962962963
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+ }
interpro_active_site/paths.json ADDED
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+ {"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C101/C101_val_log2fc"}
interpro_active_site/result.tsv ADDED
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+ Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
2
+ Nucleoside diphosphate kinase, active site [IPR023005] 0.8567591763652582 2.816372053583634 0.0048569384395626 0.231191735562743 0.0262274675736385 2 P15531 1
3
+ Peptidase family C14A, cysteine active site [IPR033139] 0.7513871449439907 2.2806444125520073 0.0225694969698586 0.7085004042254522 0.0500903767524156 4 P55212 1
4
+ Peptidase family C14A, His active site [IPR016129] 0.7513871449439907 2.2806444125520073 0.0225694969698586 0.7085004042254522 0.0500903767524156 4 P55212 1
5
+ Ubiquitin-activating enzyme E1, Cys active site [IPR033127] 0.7164179104477639 2.132610474430975 0.0329566933589635 0.836288246810935 0.0580871982535335 3 P22314,Q9UBT2 2
6
+ Protein-tyrosine phosphatase, active site [IPR016130] 0.6613192799639025 1.7723049706522995 0.0763439465754975 0.9862736469329748 0.1084887661862334 7 Q06124,P51452,O60942,Q8NCE2 4
7
+ L-lactate dehydrogenase, active site [IPR018177] 0.5520740077588702 1.3250747817839486 0.1851463493970722 0.9999842130134065 0.2173457145096065 2 P00338 1
8
+ Serine/threonine-protein kinase, active site [IPR008271] 0.5715168292762668 1.30747950425158 0.1910499113091086 0.99998933960601 0.2195041534189759 59 P36507,P49841,P68400,Q13523,O75116,P31751,Q00535,O14965,P78362,P17612,Q9NYV4,Q00534,Q9H2G2,Q15418,Q7KZI7,P19784,Q16513,O14976,P11802,Q96SB4,O15111,O96017,Q16512,Q13555,Q13464,P28482,Q99986,P49761,Q99570,P53350 30
9
+ Ubiquitin-conjugating enzyme, active site [IPR023313] 0.4537459232471753 0.7542201563351937 0.4507170363356465 0.9999999999999912 0.4772298031789199 5 P49427 1
10
+ Peptidase S9, serine active site [IPR002471] 0.3288570575947485 0.2808291331722057 0.7788414573918914 1.0 0.7935365792294742 2 P48147 1
11
+ Cysteine peptidase, cysteine active site [IPR000169] 0.2987807311213846 0.1780108471168937 0.858714457029538 1.0 0.858714457029538 3 P17655 1
interpro_active_site/selections.json ADDED
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+ {"all_annotations": ["ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenosine/AMP deaminase active site [IPR006650]", "Adenylosuccinate synthase, active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Coenzyme A transferase active site [IPR004164]", "Cysteine peptidase, cysteine active site [IPR000169]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glutaredoxin active site [IPR011767]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Lipase, GDXG, putative serine active site [IPR033140]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Peptidase family C14A, His active site [IPR016129]", "Peptidase family C14A, cysteine active site [IPR033139]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]"], "available_proteins": ["ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADA", "ADSS", "AKT2", "AMPD2", "APEH", "ATP5A1", "ATP5B", "ATP6V1A", "ATP6V1B2", "AURKA", "BLMH", "BUB1", "CAMK1", "CAMK2G", "CAPN1", "CAPN2", "CASP3", "CASP6", "CASP7", "CASP8", "CDC34", "CDC42BPB", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK4", "CDK5", "CDK6", "CDK9", "CHEK2", "CHUK", "CKB", "CKMT1A*", "CLK3", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CTSA", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLRX", "GLUD1", "GSK3A", "GSK3B", "GSR", "HADHB", "HMGCL", "HMGCS1", "LDHA", "LDHB", "LONP1", "MAP2K1", "MAP2K2", "MAP2K3", "MAP2K4", "MAP2K6", "MAP3K7", "MAPK1", "MAPK3", "MARK2", "MASTL", "MDH1", "MDH2", "MTMR14", "MTMR2", "MTMR6", "NCEH1", "NEK9", "NME1", "NME2", "OXCT1", "OXSM", "PAK1", "PAK2", "PBK", "PGAM1", "PIK3R4", "PKM", "PKMYT1", "PKN1", "PKN2", "PLK1", "PREP", "PRKAA1", "PRKAA2", "PRKACA", "PRKCB", "PRPF4B", "PTK7", "PTPN1", "PTPN11", "RIPK1", "RNASET2", "RNGTT", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SRPK2", "SUCLG1", "TALDO1", "TIGAR", "TOP1", "TPI1", "TPP2", "TTK", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2K", "UBE2L3", "UBE2M", "UBE2S", "UMPS", "VRK1", "WNK1", "YES1"], "leading_proteins": ["AKT2", "AURKA", "CAMK2G", "CAPN2", "CASP6", "CDC34", "CDK12", "CDK4", "CDK5", "CDK6", "CHEK2", "CHUK", "CLK3", "CSNK2A1", "CSNK2A2", "DUSP3", "GAK", "GSK3B", "LDHA", "MAP2K2", "MAPK1", "MARK2", "MTMR14", "NME1", "PIK3R4", "PKN1", "PKN2", "PLK1", "PREP", "PRKACA", "PRPF4B", "PTPN11", "RNGTT", "ROCK1", "ROCK2", "RPS6KA1", "SLK", "SRPK1", "SRPK2", "UBA1", "UBA2", "VRK1"]}
interpro_binding_site/advanced/idx2term.json ADDED
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+ term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500
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+ IQ motif, EF-hand binding site [IPR000048] 7 11 1.9641721193186052 0.049510134916773 4.902912621359223 10.79368932038835 -0.2273048691062784 0.5134620963427197 2.787853554074696 2.339749173467172 1.002129759133213 0.3214407723554939 0.1755724648168266 0.3209553841799009 0.2541035375726295 0.0435237537141962
interpro_binding_site/metrics.json ADDED
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+ {
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+ "signature_size": 3353,
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+ "annotations_size": 31,
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+ "title": "Average number of proteins per term",
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+ "value": 5.032258064516129
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+ }
interpro_binding_site/paths.json ADDED
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+ {"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C101/C101_val_log2fc"}
interpro_binding_site/result.tsv ADDED
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+ Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
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+ Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349] 0.7308266189197136 2.225910352486596 0.0260201867987768 0.5583801071568932 0.0733296173420074 2 P50579 1
3
+ IQ motif, EF-hand binding site [IPR000048] 0.7125239743527818 1.9641721193186057 0.049510134916773 0.792808371994419 0.1180626294169202 11 O43795,O94832,P35580,P35579,Q92614,P46940,Q15386 7
4
+ Beta tubulin, autoregulation binding site [IPR013838] 0.5536906486697772 1.2179901728783482 0.2232277071881654 0.9996027119450964 0.3008721270797012 7 P04350,Q13885,Q9BUF5 3
5
+ Protein kinase, ATP binding site [IPR017441] 0.5305966794650098 0.96512253140751 0.3344834428081153 0.9999967044735356 0.4109330574622998 56 P36507,P49841,P68400,O75116,P31751,Q00535,O14965,P78362,P17612,Q9NYV4,Q00534,Q9H2G2,Q15418,Q7KZI7,P19784,Q16513,Q96SB4,O15111,Q16512,Q13555,Q13464,P28482,Q99986,P49761,P53350 25
6
+ PPM-type phosphatase, divalent cation binding [IPR000222] 0.4882054344580557 0.9480161083037252 0.3431212537925143 0.999997801930017 0.4109330574622998 4 P49593,O15355,Q9H0C8 3
7
+ Hexokinase, binding site [IPR019807] 0.4001790510295411 0.5666525199719206 0.5709502850120776 0.9999999999959474 0.6555355124212743 2 P52789 1
8
+ Biotin-binding site [IPR001882] 0.3012839653627829 0.1734721036935777 0.8622803534663142 1.0 0.8910230319151913 4 P11498,Q13085,Q96RQ3 3
interpro_binding_site/selections.json ADDED
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+ {"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Coenzyme A transferase binding site [IPR004163]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]", "Ureohydrolase, manganese-binding site [IPR020855]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "AKT2", "APEX1", "ARG2", "AURKA", "BPNT1", "BUB1", "CALU", "CAMK1", "CAMK2G", "CAPN1", "CAPN2", "CDC42BPB", "CDK1", "CDK12", "CDK13", "CDK4", "CDK5", "CDK6", "CDK9", "CHUK", "CLK3", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CYB5B", "DBT", "DLAT", "DLST", "DST", "EHD1", "EHD4", "EIF2AK2", "EPS15", "EPS15L1", "FKBP10", "FKBP7", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3A", "GSK3B", "HK1", "HK2", "HMBS", "IDE", "ILKAP", "IQGAP1", "IQGAP2", "IQSEC1", "ITSN2", "LETM1", "MACF1", "MAP2K1", "MAP2K2", "MAP2K3", "MAP2K4", "MAP2K6", "MAP3K7", "MAPK1", "MAPK14", "MAPK3", "MARK2", "MCCC1", "METAP2", "MICU1", "MYH10", "MYH14", "MYH9", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "NFS1", "NRDC", "NUCB1", "NUCB2", "OXCT1", "OXSR1", "PA2G4", "PAK1", "PAK2", "PAK4", "PC", "PCCA", "PDCD6", "PDHX", "PEF1", "PGD", "PKMYT1", "PKN1", "PKN2", "PLCG1", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1F", "PPM1G", "PPM1L", "PRKAA1", "PRKAA2", "PRKACA", "PRKCB", "PRKCSH", "PSAT1", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "S100A11", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "SRPK2", "STK4", "TBK1", "TKT", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "UBE3C", "UQCRC2", "VRK1", "YES1"], "leading_proteins": ["ACACA", "AKT2", "AURKA", "CAMK2G", "CDK12", "CDK5", "CDK6", "CHUK", "CLK3", "CSNK2A1", "CSNK2A2", "GSK3B", "HK2", "ILKAP", "IQGAP1", "MAP2K2", "MAPK1", "MARK2", "MCCC1", "METAP2", "MYH10", "MYH9", "MYO18A", "MYO1B", "MYO1D", "PC", "PKN1", "PKN2", "PLK1", "PPM1F", "PPM1G", "PRKACA", "ROCK1", "ROCK2", "RPS6KA1", "SLK", "SRPK1", "SRPK2", "TUBB2A", "TUBB4A", "TUBB6", "UBE3C", "VRK1"]}
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+ {"0": "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "1": "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "2": "Ubiquitin specific protease, conserved site [IPR018200]", "3": "Cullin, conserved site [IPR016157]", "4": "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "5": "Kinesin motor domain, conserved site [IPR019821]", "6": "AMP-binding, conserved site [IPR020845]", "7": "Bromodomain, conserved site [IPR018359]", "8": "Zinc finger, PHD-type, conserved site [IPR019786]", "9": "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]"}
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interpro_conserved_site/df_merge.tsv ADDED
@@ -0,0 +1,2 @@
 
 
 
1
+ term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500
2
+ Phosphatidylinositol 3/4-kinase, conserved site [IPR018936] 5 7 2.428415899760516 0.0151649417818369 2.3592233009708736 5.065533980582524 -0.0414779785270424 0.5135274314368297 1.4687975990686668 1.3840549880732227 1.041360968799742 0.3265718594638703 0.0607401038440192 0.0066572828402184 8.971938182982207e-06 1.665940864684324e-05
interpro_conserved_site/metrics.json ADDED
@@ -0,0 +1,7 @@
 
 
 
 
 
 
 
 
1
+ {
2
+ "type_of_task": "ranksum",
3
+ "signature_size": 3353,
4
+ "annotations_size": 279,
5
+ "title": "Average number of proteins per term",
6
+ "value": 2.824372759856631
7
+ }
interpro_conserved_site/paths.json ADDED
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1
+ {"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C101/C101_val_log2fc"}
interpro_conserved_site/result.tsv ADDED
@@ -0,0 +1,44 @@
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
1
+ Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
2
+ Macrophage migration inhibitory factor, conserved site [IPR019829] 0.8737690241718874 2.8930903316517553 0.0038147156835786 0.6557340689631938 0.0149998265486966 2 P30046 1
3
+ Ribosomal protein S5, N-terminal, conserved site [IPR018192] 0.8522829006266746 2.7960652192833404 0.0051728960376729 0.7647211277198352 0.0183394445911261 2 P15880 1
4
+ Ras GTPase-activating protein, conserved site [IPR023152] 0.8565403990435811 2.794818295295859 0.0051928893286701 0.766036689229223 0.0183394445911261 3 P46940 1
5
+ Phosphorylase pyridoxal-phosphate attachment site [IPR035090] 0.8203521336914312 2.6497695035539595 0.0080546702225758 0.895268183772187 0.0257874624713309 2 P06737 1
6
+ Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314] 0.7961802447030683 2.5373245219351173 0.011170335275684 0.9564593618628532 0.0311652354191583 2 Q8TEA1 1
7
+ Dynamin, GTPase region, conserved site [IPR019762] 0.7860340196956077 2.489685794871203 0.0127856071928937 0.9724067741688224 0.0342998500655516 2 P50570 1
8
+ Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331] 0.7814925373134383 2.4462574016823524 0.0144347904688721 0.982693203296255 0.0376383788861246 3 Q6XZF7,Q9H8V3 2
9
+ Phosphatidylinositol 3/4-kinase, conserved site [IPR018936] 0.7940880828875694 2.428415899760516 0.0151649417818369 0.985926031751877 0.0391760996030787 7 O00443,P42356,Q13535,Q13315,P78527 5
10
+ Ubiquitin-activating enzyme E1, conserved site [IPR018074] 0.7233661593554184 2.189677273527157 0.0285476504240849 0.9996905436926176 0.0589984775431088 2 Q9UBT2 1
11
+ DNA ligase, ATP-dependent, conserved site [IPR016059] 0.7264554192657929 2.181673169469412 0.0291336624664673 0.9997384921920508 0.0594936936047054 3 P18858 1
12
+ Phosphofructokinase, conserved site [IPR015912] 0.7226106659490537 2.1629092648762085 0.0305481590431688 0.999825891139374 0.0608781169503151 3 P17858 1
13
+ tRNA-dihydrouridine synthase, conserved site [IPR018517] 0.698299015219326 2.066930405390897 0.0387407122034602 0.9999836877758688 0.0745424738259682 2 Q6P1R4 1
14
+ Fructose-bisphosphate aldolase class-I active site [IPR029768] 0.6941211578633251 2.0463245180551017 0.0407244530021897 0.9999908335465962 0.0765227781853248 2 P09972 1
15
+ Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770] 0.6938227394807515 2.044851074841573 0.0408695426020817 0.9999912123374964 0.0765227781853248 2 O60573 1
16
+ GTP1/OBG, conserved site [IPR006074] 0.6893464637421588 2.022724061914973 0.0431016046771284 0.9999954126113596 0.0780100382350314 2 Q9Y295 1
17
+ HMG box A DNA-binding domain, conserved site [IPR017967] 0.6916008390981723 2.010267768575607 0.0444028562719376 0.9999968617958628 0.0788200476295484 3 P09429 1
18
+ IMP dehydrogenase / GMP reductase, conserved site [IPR015875] 0.6776119402985132 1.9406725941942815 0.0522980025930732 0.9999996899504736 0.0889703824601673 3 Q9P2T1,P20839 2
19
+ Mrp, conserved site [IPR000808] 0.6746435904303525 1.9258481467480435 0.0541233376374425 0.9999998189375646 0.0904216239571645 3 Q9Y5Y2 1
20
+ DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464] 0.7073727809028337 1.872531406285628 0.0611331210980918 0.9999999772740976 0.1009239099785067 16 Q14562,O60231,Q14839,Q7Z478,Q8IX18,Q12873,Q86WJ1,Q92620,Q6P158,P18074,Q9UNY4 11
21
+ Dynein light chain, type 1/2, conserved site [IPR019763] 0.6571172784243453 1.8620446659348515 0.0625967945994796 0.9999999852946572 0.1021316122412562 2 P63167 1
22
+ Profilin conserved site [IPR027310] 0.607579826917332 1.6108519191081117 0.1072120017443478 0.999999999999982 0.1621155241565494 2 P07737 1
23
+ Ubiquitin specific protease, conserved site [IPR018200] 0.6569059169885605 1.609550797830045 0.1074959568779987 0.9999999999999832 0.1621155241565494 16 Q70CQ2,Q9UPT9,P40818,Q93008,Q96RU2 5
24
+ Mini-chromosome maintenance, conserved site [IPR018525] 0.587459106730899 1.413007864177577 0.1576534118148835 1.0 0.2156142249821201 6 P33993,P33991,P33992 3
25
+ Rel homology domain, conserved site [IPR030492] 0.5660996717397704 1.3975473253174784 0.1622490456857959 1.0 0.2205424054026356 2 Q00653 1
26
+ Clathrin adaptor, mu subunit, conserved site [IPR018240] 0.5669432960731753 1.376977007062654 0.1685193567366631 1.0 0.226042791007351 3 Q9BXS5 1
27
+ Proteasome beta-type subunit, conserved site [IPR016050] 0.5850516916003337 1.3608392355946868 0.1735644996744167 1.0 0.2305928352817251 8 P20618,P49721,P49720,P28072 4
28
+ Cullin, conserved site [IPR016157] 0.5748431431132425 1.347784549143037 0.1777276888284671 1.0 0.2350048586878783 6 Q13616,Q93034,Q13620,Q13617,Q13618 5
29
+ Ribosomal protein S2, conserved site [IPR018130] 0.5553566099671647 1.342044192109222 0.1795816672627257 1.0 0.2363362507844362 2 P08865 1
30
+ Tubulin, conserved site [IPR017975] 0.5536906486697772 1.2179901728783482 0.2232277071881654 1.0 0.2743635696277451 7 P04350,Q13885,Q9BUF5 3
31
+ Oxysterol-binding protein, conserved site [IPR018494] 0.5491779532515481 1.2150684642992582 0.2243399801128189 1.0 0.2745212914538442 6 Q9BZF3 1
32
+ Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412] 0.5557338856001716 1.1062813649354573 0.2686047550300945 1.0 0.3162055976936556 14 P47897,P07814,P41252,P23381,Q9P2J5,P26640 6
33
+ AT hook, DNA-binding motif [IPR017956] 0.503625590373838 1.0503490225994978 0.2935576740304939 1.0 0.3370476998127893 3 P17096 1
34
+ Kinesin motor domain, conserved site [IPR019821] 0.5046108492695173 0.8447385604056377 0.398256824916225 1.0 0.4462395749061317 14 Q15058,Q9BW19,Q96Q89,Q9Y496,O00139,Q99661,O60333 7
35
+ Actin/actin-like conserved site [IPR020902] 0.4211940298507544 0.6419292703829347 0.5209191081889026 1.0 0.5721906739555269 3 P61163,P61160 2
36
+ Sulfatase, conserved site [IPR024607] 0.4037600716204089 0.5829388314397551 0.5599344786841418 1.0 0.6126341943250022 2 P15289 1
37
+ Chromo domain, conserved site [IPR023779] 0.4107228413739149 0.5526946313018807 0.5804725302120524 1.0 0.630162785716586 5 O14646 1
38
+ AMP-binding, conserved site [IPR020845] 0.379372197309425 0.3718830394052872 0.7099799335511643 1.0 0.7618630825414416 8 O14975,Q6P1M0,P33121,Q4G176,O95573,Q96CM8,Q86V21 7
39
+ Ubiquitin conserved site [IPR019954] 0.357014925373138 0.3659190383422156 0.7144254895884747 1.0 0.7628502093185238 3 P46379,O14562 2
40
+ Ribosomal S11, conserved site [IPR018102] 0.3270665472993151 0.2748316300723444 0.7834455961840823 1.0 0.8248351748504111 2 P62263 1
41
+ Bromodomain, conserved site [IPR018359] 0.3571206852935066 0.2564049488381634 0.7976381669398629 1.0 0.8334870733191826 11 Q12830,P25440,Q9UIG0,P51532,Q9UIF9 5
42
+ Zinc finger, PHD-type, conserved site [IPR019786] 0.2793243575729205 0.0550084342571624 0.9561317444031112 1.0 0.972662486746963 18 Q12830,Q9UPP1,Q14839,Q12873,P29375 5
43
+ Zinc finger, RING-type, conserved site [IPR017907] 0.2695283728118322 0.044217896584255 0.9647307165939472 1.0 0.9752169200351856 19 Q96EP0,Q14527,Q14258 3
44
+ ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629] 0.2529777978113436 0.0309649676495106 0.9752974780330816 1.0 0.982339337080252 21 Q9UHI6,P26196,Q7L014,Q14240,Q9GZR7,Q96GQ7,Q8NHQ9 7
interpro_conserved_site/selections.json ADDED
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1
+ {"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Aldose 1-epimerase, conserved site [IPR018052]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Aminotransferase, class IV, conserved site [IPR018300]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "Arrestin, conserved site [IPR017864]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAMSAP, spectrin and Ca2+/calmodulin-binding region [IPR031372]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "CBX family C-terminal motif [IPR033773]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Carbonic anhydrase, alpha-class, conserved site [IPR018338]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific, conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA mismatch repair, conserved site [IPR014762]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "FeS cluster insertion, C-terminal, conserved site [IPR017870]", "Fibrillarin, conserved site [IPR020813]", "Fork head domain conserved site 2 [IPR030456]", "Fork head domain conserved site1 [IPR018122]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glutathione peroxidase conserved site [IPR029760]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Golgin subfamily A member 2, C-terminal binding motif [IPR043937]", "Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "Homeobox, conserved site [IPR017970]", "Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site [IPR023076]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "MoaA/NifB/PqqE, iron-sulphur binding, conserved site [IPR000385]", "Molybdenum cofactor biosynthesis, conserved site [IPR008284]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M22, conserved site [IPR017860]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site [IPR023058]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosyl pyrophosphate synthetase, conserved site [IPR000842]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Pyridoxamine 5'-phosphate oxidase, conserved site [IPR019740]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Rel homology domain, conserved site [IPR030492]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P, conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S14, conserved site [IPR018271]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium/solute symporter, conserved site [IPR018212]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Transcription factor TFIIB, conserved site [IPR023486]", "Transcription factor, T-box, conserved site [IPR018186]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Uncharacterised protein family UPF0029, Impact, conserved site [IPR020569]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]", "tRNA-dihydrouridine synthase, conserved site [IPR018517]"], "available_proteins": ["AAAS", "AACS", "AAMP", "ABCB1", "ABCB10", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACSF2", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK4", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1M1", "AP1S2", "AP2M1", "AP2S1", "AP3M1", "APEX1", "ARHGEF7", "ARIH2", "ARRB1", "ARSA", "ATAD1", "ATAD2", "ATAD2B", "ATM", "ATP5C1", "ATP5O", "ATR", "BAG6", "BAZ1A", "BAZ1B", "BAZ2A", "BCAT2", "BCS1L", "BDH2", "BLM", "BOP1", "BPNT1", "BPTF", "BRCA1", "BRD2", "BRD4", "BUD31", "CA8", "CAD", "CALR", "CAMSAP3", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CBL", "CBR1", "CBX3", "CBX4", "CBX5", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD320", "CDC40", "CDH2", "CDKAL1", "CHAF1B", "CHD1", "CHD1L", "CHD3", "CHD4", "CIAO1", "CLGN", "CMPK1", "CNDP2", "COLEC12", "COPA", "COPZ1", "CORO1A", "CORO1B", "CORO1C", "CORO7", "CPOX", "CRYZ", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CYP51A1", "DCAF13", "DCAF7", "DCPS", "DCXR", "DDT", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX31", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX55", "DDX6", "DHCR7", "DHFR", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIMT1", "DIS3", "DLG1", "DLG3", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC16", "DNAJC2", "DNAJC21", "DNAJC9", "DNM1L", "DNM2", "DNMBP", "DNMT1", "DRG1", "DRG2", "DSC2", "DSC3", "DSG2", "DST", "DTYMK", "DUS1L", "DUS2", "DYNLL1", "DYNLL2", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECT2", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EHHADH", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4E", "EIF4E2", "ENO1", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPRS", "EPS15", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FARP1", "FARP2", "FBL", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FOXC1", "FOXK1", "FOXK2", "FUCA2", "GAA", "GALK1", "GALM", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GGPS1", "GLA", "GLB1", "GLO1", "GMPPA", "GMPR2", "GNB1", "GNPDA1", "GNS", "GOLGA2", "GPHN", "GPI", "GPX8", "GRHPR", "GRWD1", "GSPT1", "GTF2B", "GTF3C2", "GUF1", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HIBADH", "HINT2", "HLA-A", "HLA-B", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCR", "HMOX1", "HMOX2", "HOXA10", "HOXD11", "HSD17B10", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "ILVBL", "IMPACT", "IMPDH1", "IMPDH2", "IQGAP1", "IQGAP2", "ISCA2", "IVD", "KATNA1", "KDM2A", "KDM5A", "KDSR", "KIF11", "KIF14", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "LAMP1", "LARS", "LARS2", "LBR", "LIG1", "LIG3", "LIG4", "LMNA", "LMNB1", "LMNB2", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK14", "MAPK3", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME1", "ME2", "MGA", "MGST2", "MID1", "MIF", "MKRN2", "MOCS1", "MPI", "MPP1", "MPP6", "MPP7", "MPST", "MRPL13", "MRPL3", "MRPS11", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS8", "NDUFV1", "NEFM", "NES", "NF1", "NFKB2", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NSD1", "NSD2", "NSF", "NSUN6", "NUBP1", "NUBP2", "NUBPL", "NUDT1", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL11", "OSBPL3", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PBRM1", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA6", "PEBP1", "PEPD", "PEX1", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHF14", "PHF2", "PHF3", "PHF8", "PHGDH", "PHIP", "PHRF1", "PI4KA", "PI4KB", "PIK3C2A", "PIN1", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PMS1", "PNP", "PNPLA6", "PNPO", "POLA1", "POLD1", "POLR1B", "POLR1C", "POLR2B", "POLR2C", "POLR3B", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PRPS2", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PUS7", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "QDPR", "RACK1", "RAE1", "RANBP2", "RARS", "RARS2", "RBBP4", "RBBP7", "RCL1", "RDH13", "RDX", "RELA", "RIDA", "RNF169", "RNF2", "RNF20", "RNF31", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS24", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "RSF1", "RTCA", "S100A11", "SART1", "SBDS", "SCAF11", "SCD", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB6", "SERPINH1", "SFN", "SLC1A5", "SLC27A2", "SLC27A4", "SLC2A1", "SLC5A6", "SLIT2", "SMARCA4", "SMS", "SMU1", "SNRNP40", "SNU13", "SORD", "SPATA5", "SPATA5L1", "SPTBN1", "SPTBN2", "SRCAP", "SRM", "STAM", "STMN1", "STRN", "STX12", "STX18", "STX4", "STX5", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SYNE2", "TAP1", "TAP2", "TBL3", "TCP1", "TFB1M", "THOC6", "TK1", "TLE4", "TLN1", "TMX1", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRAF2", "TRIM21", "TRIM24", "TRIM25", "TRIM28", "TRIM33", "TRIP13", "TRMT11", "TSFM", "TSPAN3", "TSPAN6", "TST", "TTF2", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TUFM", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UBFD1", "UHRF1", "USP10", "USP11", "USP14", "USP19", "USP22", "USP24", "USP28", "USP33", "USP34", "USP36", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VARS2", "VAT1", "VCL", "VCP", "VIM", "VPS4A", "VPS4B", "WARS", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR3", "WDR36", "WDR41", "WDR47", "WDR5", "WDR61", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2"], "leading_proteins": ["AACS", "ACSF2", "ACSF3", "ACSL1", "ACSL3", "ACTR1A", "ACTR2", "ALDOC", "AP1M1", "ARSA", "ATM", "ATR", "BAG6", "BAZ1B", "BAZ2A", "BPTF", "BRD2", "CHD1", "CHD1L", "CHD3", "CHD4", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "DDT", "DDX20", "DDX24", "DDX27", "DDX46", "DDX55", "DDX6", "DHX16", "DHX29", "DHX38", "DHX40", "DHX57", "DHX8", "DNM2", "DNMBP", "DRG1", "DUS1L", "DYNLL1", "ECT2", "EIF4A2", "EIF4E2", "EPRS", "ERCC2", "GMPR2", "HLTF", "HMGA1", "HMGB1", "IARS", "IMPDH1", "IQGAP1", "KDM5A", "KIF14", "KIF1B", "KIF20B", "KIF2A", "KIF2C", "KIF3A", "KIFC1", "LARS", "LIG1", "MCM4", "MCM5", "MCM7", "NFKB2", "NSUN6", "NUBP2", "OSBPL6", "PFKL", "PFN1", "PHF8", "PI4KA", "PIK3C2A", "PRKDC", "PSMB1", "PSMB2", "PSMB3", "PSMB6", "PYGL", "QARS", "RNF31", "RPS14", "RPS2", "RPSA", "SLC27A2", "SLC27A4", "SMARCA4", "TRIM25", "TTF2", "TUBB2A", "TUBB4A", "TUBB6", "UBA2", "UBFD1", "USP22", "USP28", "USP34", "USP8", "USP9X", "VARS1", "WARS"]}
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+ {"0": "Phosphatidylinositol 3-/4-kinase, catalytic domain [IPR000403]", "1": "TOG domain [IPR034085]", "2": "Tyrosine-specific protein phosphatases domain [IPR000387]", "3": "Importin-beta, N-terminal domain [IPR001494]", "4": "Myosin head, motor domain [IPR001609]", "5": "SNF2, N-terminal [IPR000330]", "6": "Domain of unknown function DUF1605 [IPR011709]", "7": "Helicase-associated domain [IPR007502]", "8": "Phosphoribosyltransferase domain [IPR000836]", "9": "Clathrin/coatomer adaptor, adaptin-like, N-terminal [IPR002553]", "10": "AGC-kinase, C-terminal [IPR000961]", "11": "Ubiquitin specific protease domain [IPR028889]", "12": "Peptidase C19, ubiquitin carboxyl-terminal hydrolase [IPR001394]", "13": "Helicase superfamily 1/2, ATP-binding domain [IPR014001]", "14": "Helicase, C-terminal [IPR001650]", "15": "Forkhead-associated (FHA) domain [IPR000253]", "16": "Protein kinase domain [IPR000719]", "17": "SH2 domain [IPR000980]", "18": "Glutathione S-transferase, C-terminal [IPR004046]", "19": "Glutathione S-transferase, C-terminal-like [IPR010987]", "20": "Ubiquitin-associated domain [IPR015940]", "21": "Kinesin motor domain [IPR001752]", "22": "Pleckstrin homology domain [IPR001849]", "23": "AMP-dependent synthetase/ligase [IPR000873]", "24": "Phox homology [IPR001683]", "25": "DEAD/DEAH box helicase domain [IPR011545]", "26": "CBS domain [IPR000644]", "27": "MPN domain [IPR037518]", "28": "Serine-threonine/tyrosine-protein kinase, catalytic domain [IPR001245]", "29": "Septin-type guanine nucleotide-binding (G) domain [IPR030379]", "30": "SANT/Myb domain [IPR001005]", "31": "DnaJ domain [IPR001623]", "32": "Ubiquitin-like domain [IPR000626]", "33": "Bromodomain [IPR001487]", "34": "Double-stranded RNA-binding domain [IPR014720]", "35": "Zinc finger C2H2-type [IPR013087]", "36": "Zinc finger, PHD-type [IPR001965]", "37": "Zinc finger, RING-type [IPR001841]", "38": "Zinc finger, PHD-finger [IPR019787]", "39": "RNA helicase, DEAD-box type, Q motif [IPR014014]", "40": "SH3 domain [IPR001452]", "41": "K Homology domain [IPR004087]", "42": "K Homology domain, type 1 [IPR004088]", "43": "AAA+ ATPase domain [IPR003593]"}
interpro_domain/basic/plot_0.png ADDED

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interpro_domain/basic/plot_1.png ADDED

Git LFS Details

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  • Pointer size: 131 Bytes
  • Size of remote file: 132 kB
interpro_domain/basic/plot_10.png ADDED

Git LFS Details

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  • Pointer size: 131 Bytes
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