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Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
Transport of small molecules 0.5503471838788087 5.751958968849203 8.821521262920677e-09 1.2517660382151656e-05 1.251773867350344e-05 174 Q8N4V1,Q99808,P02786,P49721,Q9C0H2,P21796,Q99436,P45880,P30519,O75027,P28070,P53985,P20618,Q70HW3,O15439,Q9H2J7,Q8WTV0,O15118,Q8TB61,P60900,P27105,P05026,Q8TAD4,Q04656,P98194,Q9BUN8,O43242,P61289,Q9NUT2,P30825,O95202,Q9UBX3,P35613,O00400,P28288,Q9HD20,P55011,P08195,Q9BPX6,P08183,Q96PU5,P61916,P51798,P33527,P07237,P33897,Q13438,Q9UBV2,Q86WC4,Q9GZP9,P09601,P51790,P28072,Q10713,Q15904,Q9NP58,P28074,Q9Y6M7,Q99758,Q99623,P10644,Q93050,P16615,P12235,Q9Y487,P12236,Q8WWC4,P51797,P04920,P23634,Q9Y277,Q9H300,Q9UEY8,P20020,P05023,Q8IYU8,Q9NW15,P40855,O00231,Q9NWR8,P05141,Q15043,Q9UJZ1 83
Metabolism of lipids 0.4560925203410695 4.779799671044427 1.7546994761641344e-06 0.0024868234597566 0.0012449592783391 211 Q15125,O60427,O15269,O15254,Q9NPH0,P50897,O43808,O15228,P37268,P16278,P35790,Q13510,Q6IAN0,Q9UMR5,Q15800,O95772,Q8NCC3,Q14739,Q15392,P04062,O95864,P50416,P07602,O00767,Q96G23,Q14849,P17900,Q71SY5,P09960,O95470,O14735,P51648,Q9NZ01,Q9HBU6,P10619,Q15165,Q16850,Q9H2C2,P23786,P27544,Q9NQZ5,Q9NRA0,Q9BWD1,Q9UKU0,O00116,O43772,Q06136,P30536,Q16880,Q8N2A8,Q53GQ0,P33527,P33897,Q96N66,P04035,Q10713,P48449,Q9HCL2,Q16739,Q8IV08,Q14534,Q9NZJ7,O75845,Q9H7Z7,Q8N5B7,P06865,Q9P035,Q92604,Q9NUQ2,P38435,P06280,Q8N8N7,O75448,Q9UBM7,Q8NF37,Q9NZC3,Q8NAN2,Q15067,Q9BTU6,O43681,Q99538 81
Intra golgi and retrograde golgi to er traffic 0.4399486155635086 3.422543341159638 0.0006203820653296 0.5854639482577544 0.2200805376756975 109 P24390,O60476,P53365,P62820,O60499,Q12981,Q15643,Q96JB2,O43731,O14653,O00461,Q9BVK6,O95721,Q8TD16,Q9UP83,Q5VZE5,P20645,Q8TBA6,O43752,O95249,Q9Y3B3,Q9NQT8,P33908,Q10472,Q9UJW0,Q15363,Q16706,O43493,Q96CN9,Q14203,O15498,Q9P2W9,Q13561,Q8N2H4,P11717,O15260,Q13190,O75935,P49755,Q10471,Q7Z6M1,P40616,P61923 43
Asparagine n linked glycosylation 0.3739359432056884 2.5058299389871332 0.0122164361302306 0.9999999733873702 0.948786685065641 130 P24390,P10619,O60476,P62820,P54727,P04844,Q96AA3,P04066,Q96JB2,O43731,Q9Y673,O14653,Q96PC5,Q9H3H5,Q13813,Q9BVK6,Q86TM6,O60762,P46977,P16278,Q9UP83,P26572,O95249,Q9Y3B3,P27824,P33908,Q9UJW0,P04843,Q15363,P15291,Q16706,Q13438,Q14203,P14314,Q9UBV2,O15498,Q01082,O15027,Q14789,Q5JRA6,Q9GZP9,Q13190,O75935,P49755,Q13724,Q12907,Q9BUN8,Q9BT22,Q13561,P61923,Q86YN1 51
Organelle biogenesis and maintenance 0.3531402860464521 2.105619851483536 0.0352373868650019 1.0 0.948786685065641 110 P24539,O95684,O75964,P06576,P41208,P00846,Q13505,Q9NX63,Q15154,O94927,P25705,P56385,A6NIH7,Q96CS2,Q9NVH1,Q16891,Q5XKP0,Q9Y512,Q9BUR5,Q6UXV4,Q13561,O75431,O75935,Q10713 24
Rho gtpase cycle 0.3284110597958816 1.9739872748241312 0.0483831899059381 1.0 0.948786685065641 170 O15173,Q96JJ3,Q15758,O95202,Q9UNZ2,P50402,Q8TAA9,P02786,O75955,Q86XL3,Q14185,Q13813,P42167,Q86UP2,Q15058,P30519,O75976,Q14254,P28288,Q9Y6M7,P62995,Q13576,Q13505,P41440,Q9UEY8,P20700,Q14739,Q86VI3,Q7Z6E9,Q9NYL9,P08670,Q8N684,Q8NBN3,Q8NHP6,Q9Y597,O15498,Q13177,Q01082,Q07065,Q13190,P27105,Q5VTR2,Q9Y512,Q9UDY2,O14964,Q13017,Q16543,Q96HY6,Q86YQ8,Q5JTV8,P51572,Q9BT78,Q68EM7,P51648,Q7L576,Q9UQB8,Q15904 57
Surfactant metabolism 0.9114744854806904 1.950597803985406 0.051104908655597 1.0 0.948786685065641 2 Q07065 1
Keratan sulfate biosynthesis 0.9058359176769126 1.9261843330715032 0.0540813613479791 1.0 0.948786685065641 2 O43505 1
Pre notch processing in golgi 0.90380818053597 1.9149489198084195 0.0554990181847296 1.0 0.9601676471567794 4 Q9UBV2,Q15363,P15291 3
Protein localization 0.5863018088217443 1.903152741820631 0.0570206175900067 1.0 0.9601676471567794 82 O60830,Q99595,P50402,Q9NS69,O15254,P21796,Q8N4H5,O43808,O15228,P06576,Q9Y5L4,P05067,O14925,P46379,Q9Y584,Q13505,O75381,Q9NX63,Q9Y5J6,O00116,P25705,O60220,Q15067,Q9Y5J9,P33897,P40855,O75431,Q9NR77,Q13190,Q9Y512,P09601,O43615,Q13011,O43681,P12235,Q15388,Q96B49,O75746,Q5JRX3,Q9UJS0,P51648,P12236,Q9Y3D6,Q10713 44
Bicarbonate transporters 0.8894840710459566 1.855144273671732 0.0635756269222309 1.0 0.9601676471567794 2 Q9Y6M7 1
Hs gag degradation 0.8896983063903978 1.854394100326408 0.0636827982387422 1.0 0.9601676471567794 3 P16278 1
Acyl chain remodelling of pg 0.8841274316323662 1.8317973608444744 0.0669816165994836 1.0 0.9601676471567794 2 Q92604 1
Keratan sulfate keratin metabolism 0.880560831114353 1.811491741361554 0.0700647663171682 1.0 0.9601676471567794 6 O43505,P15586,P16278,P15291 4
Heme degradation 0.8778041678422361 1.8008005760849992 0.0717343180599379 1.0 0.9601676471567794 4 P30519,P33527 2
Vesicle mediated transport 0.2931519399046999 1.7632454900626082 0.0778590944940691 1.0 0.9601676471567794 285 P24390,Q14108,P02786,Q15643,O43731,O00461,Q8TD16,O75976,O43752,Q9UJW0,Q8WTV0,Q15363,Q16706,O43493,P55327,Q99523,Q9P2W9,Q07954,P11717,Q7Z6M1,Q9BRG1,O60499,Q96JB2,Q9UNF0,O14653,Q96A65,Q9UP83,Q9UIQ6,P86790,Q9Y3B3,Q9NQT8,Q10472,O60749,Q14203,Q01082,O95295,Q5KU26,P62258,O15027,O15260,Q14789,Q5JRA6,Q9UPT5,Q12907,Q9BT78,P98164,P40616,Q13561,P50570,P51809,P61923,O75935,O60476,P62820,Q96PC5,Q13813,Q9BVK6,O95721,Q5VZE5,P09496,Q9H9H4,O95249,Q9BXS5,Q99627,P14625,P33908,P15586,O15498,Q8N2H4,Q9Y3E7,Q13190,O14964,Q10471,Q8TAG9,P84085,P53365,Q12981,Q12846,P05067,P20645,Q8TBA6,P61020,Q96CN9,P31751,P49755 85
Keratan sulfate degradation 0.8684760258404347 1.7596486493082362 0.0784673974630458 1.0 0.9601676471567794 4 P15586,P16278 2
O linked glycosylation 0.8675835083362353 1.7557059235770636 0.079138634847883 1.0 0.9601676471567794 4 Q10472,Q8N4A0 2
O linked glycosylation of mucins 0.8675835083362351 1.7557059235770636 0.079138634847883 1.0 0.9601676471567794 4 Q10472,Q8N4A0 2
Mucopolysaccharidoses 0.8657646881347347 1.7476684282866235 0.0805214587819991 1.0 0.9601676471567794 4 P16278,P54802 2
Metal ion slc transporters 0.8587538765153524 1.7207396660716334 0.0852980750558445 1.0 0.9759684474741618 2 Q8TAD4 1
Zinc transporters 0.8587538765153524 1.7207396660716334 0.0852980750558445 1.0 0.9759684474741618 2 Q8TAD4 1
Proton coupled monocarboxylate transport 0.8384550324217519 1.6313953211130747 0.1028069315334949 1.0 1.0 2 P35613 1
Er quality control compartment erqc 0.8393700457446348 1.6289265629532943 0.103328566087014 1.0 1.0 5 Q13438,Q9UBV2,Q9GZP9 3
Transport of bile salts and organic acids metal ions and amine compounds 0.8391647855530358 1.6280099100826124 0.1035227844596637 1.0 1.0 5 P35613,Q9H2J7,Q8TAD4,Q15043 4
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane 0.8359323136452541 1.6135694026838745 0.1066208580609484 1.0 1.0 5 P12236,P05141,P12235 3
Synthesis secretion and inactivation of glucose dependent insulinotropic polypeptide gip 0.8243090806542394 1.5660450790921123 0.1173380641160133 1.0 1.0 3 P67812,Q15005 2
Synthesis secretion and deacylation of ghrelin 0.8243090806542394 1.5660450790921123 0.1173380641160133 1.0 1.0 3 P67812,Q15005 2
Transport of vitamins nucleosides and related molecules 0.8247821384155183 1.563388506051984 0.1179612419919338 1.0 1.0 8 O00400,P05141,P12235,P12236,Q8TB61 5
Sphingolipid metabolism 0.7997586466799214 1.5576514946978168 0.1193158846310007 1.0 1.0 28 P10619,P06280,Q16739,P27544,P16278,Q9NRA0,Q13510,Q9NZJ7,Q06136,P04062,Q16880,Q8N5B7,P06865,P07602,Q96G23,P17900,O43681,O95470,P51648 19
Linoleic acid la metabolism 0.8225835905041451 1.555870683038273 0.1197388459876394 1.0 1.0 4 O60427,P33897 2
Membrane trafficking 0.2849059878860649 1.5488253448886486 0.1214237111319593 1.0 1.0 277 P24390,Q14108,P02786,Q15643,O43731,O00461,Q8TD16,O75976,O43752,Q9UJW0,Q15363,Q16706,O43493,P55327,Q99523,Q9P2W9,P11717,Q7Z6M1,Q9BRG1,O60499,Q96JB2,Q9UNF0,O14653,Q96A65,Q9UP83,Q9UIQ6,P86790,Q9Y3B3,Q9NQT8,Q10472,O60749,Q14203,Q01082,O95295,P62258,O15027,O15260,Q14789,Q5JRA6,Q9UPT5,Q12907,Q9BT78,P98164,P40616,Q13561,P50570,P51809,P61923,O75935,O60476,P62820,Q96PC5,Q13813,Q9BVK6,O95721,Q5VZE5,P09496,Q9H9H4,O95249,Q9BXS5,Q99627,P33908,P15586,O15498,Q8N2H4,Q9Y3E7,Q13190,O14964,Q10471,Q8TAG9,P84085,P53365,Q12981,Q12846,P05067,P20645,Q8TBA6,P61020,Q96CN9,P31751,P49755 81
Cytochrome p450 arranged by substrate type 0.8175426585141647 1.535981281028951 0.1245429714134176 1.0 1.0 3 Q16850 1
Glycosphingolipid metabolism 0.8124708257374957 1.5286788685111463 0.1263440733938843 1.0 1.0 16 P10619,P17900,P16278,P04062,Q13510,P06280,Q16880,Q9NZJ7,Q16739,P06865,P07602 11
Reactions specific to the complex n glycan synthesis pathway 0.8150549760360872 1.5279552290216023 0.1265236542397771 1.0 1.0 2 Q16706 1
N glycan antennae elongation in the medial trans golgi 0.8152848279751875 1.5259426838711958 0.1270241393048552 1.0 1.0 3 Q16706,P15291 2
Glycerophospholipid catabolism 0.811107978573447 1.510469463830132 0.1309236754703304 1.0 1.0 2 Q9NZC3 1
Pregnenolone biosynthesis 0.8076568550421293 1.4869120987572673 0.1370380283805183 1.0 1.0 5 Q14849,O95772 2
Synthesis of pg 0.7959353368619859 1.439796645864218 0.1499249404307157 1.0 1.0 3 Q8N2A8 1
Chondroitin sulfate dermatan sulfate metabolism 0.7913745878150262 1.416383733111598 0.156663183979298 1.0 1.0 4 Q8NCH0 1
Sphingolipid de novo biosynthesis 0.7893982553380722 1.4071662303880714 0.1593781026844518 1.0 1.0 12 Q96G23,P51648,P27544,Q06136,Q9NRA0,O95470,Q8N5B7 7
Synthesis of pe 0.7780597856739861 1.360090406045218 0.1738013166977985 1.0 1.0 3 P35790,Q9HBU6 2
Metabolism of steroid hormones 0.7775233363211542 1.348419221838082 0.1775235850179743 1.0 1.0 7 Q14849,P30536,O95772 3
Cholesterol biosynthesis 0.7696340098096374 1.3290828450226984 0.1838206393372214 1.0 1.0 17 P37268,Q14739,Q15125,Q15392,Q14534,O75845,Q9BWD1,Q16850,P04035,Q9H2C2,Q15800,P48449 12
Glycosaminoglycan metabolism 0.769433137898464 1.328123183480759 0.1841374157979096 1.0 1.0 17 P15586,P16278,P54802,O43505,Q7LGA3,P15291,Q8NCH0,Q8TB61 8
Wax and plasmalogen biosynthesis 0.7705981941309106 1.3203433086841103 0.186720422084464 1.0 1.0 5 O00116,Q96K12,Q6IAN0,O15228 4
Hs gag biosynthesis 0.7676254935138169 1.313547414540727 0.1889985548503883 1.0 1.0 3 Q7LGA3,O94923 2
Trafficking and processing of endosomal tlr 0.7654355793628445 1.307700908093976 0.1909747752230388 1.0 1.0 2 Q99538 1
N glycan trimming and elongation in the cis golgi 0.7653694303440547 1.303485021082725 0.1924092269228057 1.0 1.0 3 O60476,P26572 2
Pink1 prkn mediated mitophagy 0.7613131523676689 1.27460478225726 0.2024491639658714 1.0 1.0 10 Q8IWA4,Q9NS69,Q15388,Q96B49,P21796,Q8N4H5 6
Slc mediated transmembrane transport 0.7455058271839436 1.2490262955283309 0.2116554562897687 1.0 1.0 24 O00400,P53985,P04920,Q9H2J7,Q9UBX3,Q99808,Q9Y6M7,Q8TAD4,P05141,P12235,P55011,Q15043,Q8TB61,P12236,P30825,P35613,Q70HW3 17
Amino acid transport across the plasma membrane 0.7542816371021803 1.2469897447959586 0.2124012578597485 1.0 1.0 5 Q9H2J7 1
Endosomal vacuolar pathway 0.7470013384016867 1.2177279579434213 0.2233273690253197 1.0 1.0 4 P04439,Q9UIQ6 2
Nr1h2 nr1h3 regulate gene expression linked to lipogenesis 0.7437270933183033 1.2113317586592427 0.2257682817112034 1.0 1.0 2 O00767 1
Synaptic adhesion like molecules 0.7464814206372987 1.2088767978487842 0.2267101812844825 1.0 1.0 6 O75955,Q14254,O95197,P10586 4
Abc transporters in lipid homeostasis 0.7440969473637977 1.2012545598147992 0.2296524711048071 1.0 1.0 5 P40855,Q99758,P33897 3
Vitamin d calciferol metabolism 0.7430413553805146 1.1965178442015274 0.2314945393385739 1.0 1.0 5 P04062,Q99538,P38435 3
Platelet calcium homeostasis 0.7382628112516627 1.1750853278945577 0.239960579972505 1.0 1.0 5 P23634,Q13586,P16615 3
Diseases associated with glycosaminoglycan metabolism 0.7379221984573565 1.170318342875606 0.2418728829035892 1.0 1.0 6 Q8NCH0,P15291 2
Synthesis of very long chain fatty acyl coas 0.7382790359488218 1.1695137157248714 0.2421967184787248 1.0 1.0 8 Q9UKU0,Q53GQ0,Q9NZ01 3
Plasma lipoprotein remodeling 0.7279391034677232 1.1414143702555035 0.2536975274291511 1.0 1.0 2 P07237 1
Maturation of sars cov 1 spike protein 0.7303211129917435 1.1395079562474402 0.2544913517148526 1.0 1.0 5 P27824,P14314,P26572 3
Heparan sulfate heparin hs gag metabolism 0.7248748093489691 1.109979754101147 0.2670077508718254 1.0 1.0 7 Q7LGA3,P54802,P16278 3
Mitochondrial protein import 0.6917889853817214 1.1089645789620457 0.2674454627320584 1.0 1.0 38 O60830,Q99595,Q9NS69,P21796,Q8N4H5,P06576,Q9Y5L4,O14925,Q9Y584,Q13505,Q9NX63,Q9Y5J6,P25705,O60220,Q9Y5J9,O75431,Q9Y512,O43615,P12235,Q15388,Q96B49,O75746,Q5JRX3,Q9UJS0,P12236,Q10713 26
Synthesis secretion and inactivation of glucagon like peptide 1 glp 1 0.7179465530830867 1.0842062323160646 0.2782733689779348 1.0 1.0 5 P67812,Q15005 2
Incretin synthesis secretion and inactivation 0.7179465530830867 1.0842062323160646 0.2782733689779348 1.0 1.0 5 P67812,Q15005 2
Acyl chain remodelling of pc 0.7146884691288238 1.0829247244263225 0.2788418365604601 1.0 1.0 2 Q8NF37 1
Basigin interactions 0.7180265804432773 1.0791297211473263 0.2805299035737736 1.0 1.0 7 P53985,P35613,P05026 3
The citric acid tca cycle and respiratory electron transport 0.3728802500716482 1.0706532353228793 0.2843253772691909 1.0 1.0 99 Q86Y39,P24539,Q16134,Q9Y6M9,O75964,P21796,Q9P0J0,P35613,P06576,Q13423,P03886,O43676,P21912,O14949,P00846,Q8N8Q8,P20674,P22695,Q9UDW1,P25705,P13073,P56385,Q9NPL8,O95139,P00403 25
Attachment of gpi anchor to upar 0.7088619305608256 1.0437390938678446 0.2966061173236363 1.0 1.0 5 Q9H490,O43292 2
Neutrophil degranulation 0.2772391376389237 1.0430969079203527 0.296903412643033 1.0 1.0 183 P10619,O00264,Q99536,P06280,P04066,Q99436,Q8NF37,Q969Q5,P16278,P30519,Q13510,Q9NZJ7,Q92820,Q13576,P04439,Q9NQX7,Q9NV96,P13473,P11279,P20618,Q5T9A4,P15586,O75787,Q9BTY2,Q93050,P61020,P15291,Q9H7Z7,Q08722,O00231,P42785,P07602,P11717,Q07065,P17900,O15260,P09960,P27105,P10253,O00754,O00584,O43681,Q92542,O43242,Q8NHP6 45
Class i peroxisomal membrane protein import 0.7108495918266202 1.042836888230727 0.2970238435292285 1.0 1.0 12 Q9NR77,O75381,P33897,P40855,P51648,Q9Y3D6,O43808 7
Metabolism of fat soluble vitamins 0.709407881755284 1.0424061723006834 0.2972234060547016 1.0 1.0 6 P98164,Q8N0U8,Q07954 3
Cristae formation 0.7011961268519797 1.0195749331020254 0.3079300983345776 1.0 1.0 22 P25705,Q5XKP0,P56385,O75431,Q9Y512,P24539,Q9NVH1,Q16891,P00846,Q13505,O75964,Q9NX63,Q6UXV4,P06576 14
Insertion of tail anchored proteins into the endoplasmic reticulum membrane 0.7043618529097322 1.0131817676582189 0.3109733474979181 1.0 1.0 11 Q13190,P05067,P09601,P50402,O43681,P46379,P51648 7
Constitutive signaling by overexpressed erbb2 0.699084576342477 1.0093302809533071 0.3128162624273567 1.0 1.0 3 Q16543 1
Ecm proteoglycans 0.6961441633270053 0.996412821022598 0.3190496060922325 1.0 1.0 3 P05067 1
Transport of inorganic cations anions and amino acids oligopeptides 0.6988509803719468 0.987753914651746 0.3232731827705946 1.0 1.0 12 Q9H2J7,Q9UBX3,Q9Y6M7,P30825,Q70HW3 5
Diseases associated with n glycosylation of proteins 0.6945702987235733 0.9740347987605924 0.3300392611988316 1.0 1.0 7 Q96AA3,Q9BT22,P15291 3
Reduction of cytosolic ca levels 0.6918934057547944 0.9729510187407804 0.3305776465935426 1.0 1.0 4 P23634,P16615 2
Synthesis of pa 0.695547240891316 0.972638822474243 0.3307328405579408 1.0 1.0 12 Q8NAN2,Q9NPH0,Q8N2A8,Q9HCL2,Q8NF37,Q9NUQ2 6
Tryptophan catabolism 0.6848040597688255 0.9520260715572576 0.3410837597871621 1.0 1.0 2 P08195 1
Stimuli sensing channels 0.6892090628694515 0.9437117514231792 0.3453169672183751 1.0 1.0 12 Q86WC4,P27105,P51797,P51798,P51790,Q9C0H2 6
Mitochondrial calcium ion transport 0.6857653960878834 0.9329032276349476 0.3508699357499201 1.0 1.0 18 Q99623,P45880,O95202,Q8IYU8,Q9Y277,Q10713,Q9H300,P21796,Q9NWR8,Q8WWC4 10
Sumo is proteolytically processed 0.6769100648435318 0.9177696665121804 0.3587394660145833 1.0 1.0 2 Q9P0U3 1
Mitophagy 0.6786899017150942 0.8955497465097948 0.3704932855933338 1.0 1.0 13 Q8IWA4,Q9NS69,Q15388,Q96B49,P21796,Q8N4H5 6
Cobalamin cbl vitamin b12 transport and metabolism 0.6723447603091499 0.8827423661677801 0.3773754861921661 1.0 1.0 5 P33527 1
Prevention of phagosomal lysosomal fusion 0.6688293370944955 0.8722097944840115 0.3830939372182924 1.0 1.0 4 O14964,P20339,P51149 3
Peptide ligand binding receptors 0.6691558555055331 0.861581477756262 0.3889178671770827 1.0 1.0 7 P42892,Q9NZJ7,P07602 3
Class a 1 rhodopsin like receptors 0.6691558555055331 0.861581477756262 0.3889178671770827 1.0 1.0 7 P42892,Q9NZJ7,P07602 3
Formation of atp by chemiosmotic coupling 0.6638141007229411 0.8300686677634059 0.4064999607668986 1.0 1.0 11 P25705,P24539,P00846,O75964,P06576 5
Ion transport by p type atpases 0.6584090154589887 0.8048058912281048 0.4209317015263527 1.0 1.0 12 P23634,P05023,P05026,Q9HD20,Q04656,P16615,P20020 7
Immunoregulatory interactions between a lymphoid and a non lymphoid cell 0.6543867483804888 0.797169224269284 0.4253527571154349 1.0 1.0 7 P04439,Q5KU26,P10321 3
Gpcr ligand binding 0.6550222353340107 0.7947872043797756 0.4267372954099564 1.0 1.0 9 P42892,Q9NZJ7,P07602 3
Nef mediated downregulation of mhc class i complex cell surface expression 0.6511559130440088 0.791086294231108 0.4288936365458164 1.0 1.0 5 P04439,Q9BXS5 2
Diseases of carbohydrate metabolism 0.6543754154944571 0.7899015587992424 0.4295852609680772 1.0 1.0 10 P16278,P54802,P10253 3
Wnt ligand biogenesis and trafficking 0.6481695284785453 0.7735214760431839 0.4392138238552991 1.0 1.0 6 Q9Y3A6,Q5T9L3 2
Miscellaneous transport and binding events 0.6492880869204307 0.7722747659337301 0.4399517076237371 1.0 1.0 8 Q8N4V1 1
Metabolism of porphyrins 0.6441178878863216 0.7450530298126896 0.4562396624004254 1.0 1.0 10 P30519,P09601,P33527 3
Intra golgi traffic 0.6448648626455327 0.7443644188869355 0.4566560387400633 1.0 1.0 19 O95721,O60476,P33908,Q9UP83,Q13190,Q8TBA6,Q15643,Q96JB2,O43752,O95249,O14653,Q16706,O00461 13
Egr2 and sox10 mediated initiation of schwann cell myelination 0.6369284095622154 0.7255968590872235 0.4680859471685994 1.0 1.0 6 P04035,Q16850 2
Establishment of sister chromatid cohesion 0.6268218847782738 0.6761679633229657 0.4989340102998334 1.0 1.0 8 Q14683,Q8WVM7,Q9UQE7 3
Inflammasomes 0.6238954995987125 0.6759488111421582 0.499073145698873 1.0 1.0 5 P09601,Q96RD7 2
The nlrp3 inflammasome 0.6238954995987125 0.6759488111421582 0.499073145698873 1.0 1.0 5 P09601,Q96RD7 2
Calnexin calreticulin cycle 0.6241685191981071 0.6593126907439241 0.5096949946865386 1.0 1.0 10 Q13438,Q86TM6,Q9UBV2,Q9GZP9 4
Synthesis of pc 0.6141211068462811 0.6356220639171951 0.5250227849907949 1.0 1.0 5 Q8NF37,Q9NQZ5 2
Post translational modification synthesis of gpi anchored proteins 0.6126377696113755 0.6137044739782628 0.5394106313876605 1.0 1.0 9 Q9H490,O43292,Q5H8A4,Q92643 4
Retrograde transport at the trans golgi network 0.6119151679158553 0.602860935919572 0.5466012051473372 1.0 1.0 24 P11717,P53365,Q9UP83,P20645,O60499,Q96JB2,O43752,Q96CN9,O43493,P40616,Q7Z6M1,Q8N2H4 12
Cohesin loading onto chromatin 0.6029817649125722 0.5708642859875531 0.568091641751872 1.0 1.0 10 Q14683,Q8WVM7,Q9UQE7 3
Ion channel transport 0.5946677217994438 0.5638297591155644 0.5728699968331918 1.0 1.0 34 P51797,Q9C0H2,P23634,Q9HD20,P20020,Q96PU5,P05023,Q93050,P51798,Q9NW15,P16615,Q86WC4,P05026,P27105,Q04656,P51790,P98194,Q9Y487,Q15904 19
Fatty acids bound to gpr40 ffar1 regulate insulin secretion 0.5897941922751609 0.5562671874996974 0.5780282147698608 1.0 1.0 2 P29992 1
Processing of smdt1 0.5949156916882012 0.5301649475227224 0.5959975718254154 1.0 1.0 13 Q99623,Q8IYU8,Q10713,Q9H300,Q9BPX6,Q9UJZ1,Q9NWR8,Q8WWC4 8
Interaction between l1 and ankyrins 0.5816668338274816 0.5122103357764993 0.6085038101881293 1.0 1.0 4 Q01082 1
Alpha oxidation of phytanate 0.5815617376969691 0.5059417828921206 0.6128975191892987 1.0 1.0 5 P51648 1
Rhog gtpase cycle 0.5736856219982439 0.4889986713789012 0.6248426374799676 1.0 1.0 38 O15173,Q96JJ3,O95202,Q6IAA8,P50402,Q8TAA9,P02786,Q86XL3,Q14185,P42167,Q86UP2,P42166,Q13576,Q14739,O15498,Q13190,Q13017,Q13177,Q7L576 19
Runx1 regulates expression of components of tight junctions 0.5732554148184322 0.4863650321967356 0.6267083783843899 1.0 1.0 3 Q16625 1
Activation of bad and translocation to mitochondria 0.5771621815166302 0.4790587061496315 0.6318968653284194 1.0 1.0 7 P31751 1
Aspartate and asparagine metabolism 0.5718847912687733 0.4690254014302659 0.639051479535915 1.0 1.0 5 Q9UJS0 1
Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps 0.5816706730427883 0.4671327462515734 0.6404049069776452 1.0 1.0 21 P14625,Q07065,O43852,Q86UP2,P05067,Q5JRA6,Q9BTY2,Q08431,Q02818,Q8NBJ4,Q06481,P07237,O43493,O76024 14
Met activates ptk2 signaling 0.5565266422328872 0.4311309540135208 0.6663731546620562 1.0 1.0 2 Q05397 1
Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins 0.4853790732203339 0.4249224010599933 0.6708932440385476 1.0 1.0 67 Q86Y39,P24539,Q16134,Q9Y6M9,O75964,Q9P0J0,P06576,P03886,O43676,P21912,O14949,Q8N8Q8,P20674,P00846,P22695,Q9UDW1,P25705,P13073,P56385,Q9NPL8,O95139,P00403 22
Sialic acid metabolism 0.5590595550484427 0.4214424156554952 0.6734320519823895 1.0 1.0 5 P16278 1
Rac2 gtpase cycle 0.5621035153447275 0.4163061361614417 0.677186003018742 1.0 1.0 35 O15173,Q14739,P42167,Q9Y512,P50402,Q8TAA9,Q13505,Q86XL3,Q68EM7 9
Metabolism of steroids 0.5231936738529017 0.3860615110592086 0.6994511140159647 1.0 1.0 53 Q15125,P38435,Q16850,Q9HCL2,Q9H2C2,P37268,Q14534,Q9BWD1,Q15800,O95772,Q14739,Q15392,P04062,P30536,O75845,Q53GQ0,Q14849,P04035,P48449 19
G2 m dna replication checkpoint 0.5461054924022977 0.3811566946774755 0.7030869805832523 1.0 1.0 4 P06493,Q99640 2
N glycan trimming in the er and calnexin calreticulin cycle 0.5548182141333714 0.3636659461466119 0.7161074756331642 1.0 1.0 17 Q9GZP9,Q9BUN8,Q13438,Q9UBV2,Q86TM6 5
Purinergic signaling in leishmaniasis infection 0.5409386849343292 0.3631991339146702 0.7164561345531808 1.0 1.0 4 P09601 1
Cargo concentration in the er 0.553254895187691 0.3577643712663494 0.7205196557121167 1.0 1.0 17 Q13190,Q5JRA6,P49755,Q15363,O14653,Q96PC5 6
Presynaptic function of kainate receptors 0.5311530871158845 0.342968827464775 0.7316219114784355 1.0 1.0 2 Q01970 1
Nr1h2 and nr1h3 mediated signaling 0.5370753552861852 0.3332395976350666 0.7389534300294367 1.0 1.0 7 Q9HCE1,Q8NB78,O00767 3
Depolymerisation of the nuclear lamina 0.5409112285988809 0.329825695413472 0.7415316706873873 1.0 1.0 11 P20700,P42167,P50402,P42166,P06493,P02545 6
Tlr3 mediated ticam1 dependent programmed cell death 0.5241048773611627 0.3197867834727026 0.7491299672113017 1.0 1.0 2 Q13546 1
Trif mediated programmed cell death 0.5241048773611627 0.3197867834727026 0.7491299672113017 1.0 1.0 2 Q13546 1
Tnfr1 induced proapoptotic signaling 0.5241048773611627 0.3197867834727026 0.7491299672113017 1.0 1.0 2 Q13546 1
Defective ripk1 mediated regulated necrosis 0.5241048773611627 0.3197867834727026 0.7491299672113017 1.0 1.0 2 Q13546 1
Conversion from apc c cdc20 to apc c cdh1 in late anaphase 0.5379057181657718 0.3193501920540659 0.7494609758321786 1.0 1.0 11 Q9UJX5,P30260,Q12834,Q9UJX3,Q9UJX4 5
Peptide hormone metabolism 0.541547780762603 0.3168210932483967 0.7513793579920551 1.0 1.0 16 Q15005,Q96A65,O75787,Q8TAD4,P61009,P67812 6
Rnd1 gtpase cycle 0.539115900059023 0.3135492188608081 0.7538634331792791 1.0 1.0 14 Q15058,O75976,Q14254,Q8TAA9,P02786,P51648 6
Ire1alpha activates chaperones 0.5409944925782003 0.3060031225376136 0.7596022683091328 1.0 1.0 28 Q9Y5M8,Q9NWM8,O14773,O95070,P43307,O43731,Q86TM6 7
Integrin cell surface interactions 0.5266749662836708 0.3032517837140732 0.7616979880723114 1.0 1.0 6 Q08722,P35613,P06756 3
Beta oxidation of pristanoyl coa 0.5225820645068568 0.3019510412795442 0.7626893852708374 1.0 1.0 4 O15254,P22307 2
Diseases of glycosylation 0.5373451113538547 0.292593749942812 0.7698326916279132 1.0 1.0 21 P10619,P16278,O43505,P15291,Q96AA3,Q9BT22,Q8NCH0,P06865 8
Pre notch expression and processing 0.5211525676932446 0.2631268052758079 0.7924528440774052 1.0 1.0 11 Q9UBV2,P15291,Q15363 3
Glycerophospholipid biosynthesis 0.5266074940642003 0.2603398981500942 0.7946015990589204 1.0 1.0 34 Q8NCC3,Q9HBU6,Q9NQZ5,Q8NAN2,P35790,Q96N66,Q9NPH0,Q8N2A8,Q92604,O14735,Q9HCL2,Q8IV08,Q8NF37,O15228,Q9NUQ2 15
Striated muscle contraction 0.5078660345000744 0.2439958276571162 0.807234051329182 1.0 1.0 6 Q9NYL9,P08670 2
Inla mediated entry of listeria monocytogenes into host cells 0.4978855370735913 0.2391695181879244 0.8109741377938995 1.0 1.0 2 O60716 1
E2f enabled inhibition of pre replication complex formation 0.5038041654903623 0.2377232603506631 0.8120957416142052 1.0 1.0 5 P06493,Q9Y619 2
Ion homeostasis 0.5133556522257527 0.2307153200557574 0.8175359709070338 1.0 1.0 13 P23634,Q13586,P05023,P16615,P20020 5
Collagen biosynthesis and modifying enzymes 0.5102279868318411 0.2285671372559805 0.8192053690926895 1.0 1.0 11 Q32P28,O60568,O75718,P07237,P13674 5
Transport to the golgi and subsequent modification 0.3686388275357772 0.2237564271886981 0.8229468363634633 1.0 1.0 87 P24390,O60476,P62820,P04066,Q96JB2,O43731,O14653,Q96PC5,Q13813,Q9BVK6,Q9UP83,P26572,O95249,Q9Y3B3,P33908,Q9UJW0,Q15363,P15291,Q16706,Q14203,Q01082,P61923,O15027,Q14789,Q5JRA6,Q13190,P49755,Q12907,Q13561,O75935 30
Unwinding of dna 0.5043576724667667 0.2192524949230707 0.8264533650940229 1.0 1.0 9 Q14566,P49736,P33991 3
Apc c cdc20 mediated degradation of cyclin b 0.5064773492766264 0.2093964598554011 0.8341387561376647 1.0 1.0 13 Q9UJX5,Q13042,P30260,Q12834,P06493,Q9UJX3,Q9UJX4 7
Plasma lipoprotein clearance 0.5079481948638285 0.2070244034716672 0.8359908001163765 1.0 1.0 15 Q8WTV0 1
Class b 2 secretin family receptors 0.4843529743445353 0.2013116161034295 0.8404549201600253 1.0 1.0 2 Q9UBI6 1
Phospholipid metabolism 0.4899046646721532 0.1985689918045833 0.8425999115089253 1.0 1.0 51 Q9HBU6,Q8TBX8,Q9NPH0,Q9UG56,Q9HCL2,Q8IV08,Q8NF37,O15228,Q8IY17,Q9NQZ5,Q9UBF8,P35790,Q8NCC3,Q9NZC3,Q8NAN2,Q8N2A8,Q9NTJ5,O95674,Q9BTU6,Q96N66,Q92604,O14735,Q9BZF1,Q10713,Q99943,Q9NUQ2 26
Response of eif2ak1 hri to heme deficiency 0.4805414551607526 0.184838429444379 0.8533557648348475 1.0 1.0 3 P20042,P08243 2
Ca dependent events 0.4855377073631572 0.1704777826850269 0.8646344054502157 1.0 1.0 8 P52292 1
Protein protein interactions at synapses 0.4945810969706729 0.1670821328675473 0.867305424297834 1.0 1.0 15 O95197,Q14254,P10586,O75955,P41440 5
Signaling by erbb4 0.4818215627616105 0.1606021711157285 0.8724067447948944 1.0 1.0 8 P46934 1
Binding and uptake of ligands by scavenger receptors 0.4810691253215873 0.1586295390392519 0.8739607546740578 1.0 1.0 8 Q8WTV0 1
Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux 0.4745384488739319 0.1573551945886141 0.8749649230149421 1.0 1.0 5 Q8NB78 1
Synthesis of pips at the golgi membrane 0.4800145847134242 0.1558802587129189 0.8761274063437041 1.0 1.0 8 Q9BTU6,Q10713,Q9UBF8 3
Insulin processing 0.4797774199709358 0.1461737262642149 0.8837842461610002 1.0 1.0 10 Q96A65,O00471,Q96KP1,Q8TAD4,Q9UPT5,Q8TAG9 6
Irf3 mediated induction of type i ifn 0.4692437923250516 0.1442379806231241 0.8853125503096029 1.0 1.0 5 P12956,P49959,Q9UJV9,P78527 4
Sting mediated induction of host immune responses 0.4693762348292229 0.1388665855068361 0.8895555759866685 1.0 1.0 6 P78527,Q9UJV9,P12956,P49959,P19474 5
Fatty acyl coa biosynthesis 0.484198605503756 0.134659223304093 0.8928813145498937 1.0 1.0 16 Q9NZ01,Q53GQ0,Q9UKU0,Q9UMR5,P50897 5
Translation of sars cov 1 structural proteins 0.4689196442475439 0.1280538005228011 0.8981063967997989 1.0 1.0 8 P27824,P14314,P26572,Q10472 4
Mitochondrial biogenesis 0.4873260934476988 0.1275289224836281 0.8985217832321639 1.0 1.0 40 P25705,Q5XKP0,P56385,O75431,Q9Y512,P24539,Q9NVH1,Q16891,P00846,Q13505,O75964,Q9NX63,Q6UXV4,P06576 14
Rhod gtpase cycle 0.4899476104870858 0.124564291803051 0.9008684991720656 1.0 1.0 30 O15173,P20700,Q14739,P42167,P50402,Q8TAA9,Q9Y6M7,Q5JTV8,Q8NHP6,Q68EM7,Q9UEY8 11
Dopamine neurotransmitter release cycle 0.449393853961102 0.11649344857559 0.9072614780278832 1.0 1.0 2 Q13136 1
E3 ubiquitin ligases ubiquitinate target proteins 0.4746914825569102 0.1062676827652557 0.9153699717851776 1.0 1.0 17 Q9GZS3,O75150,Q92541,P04439,Q9BUN8,O75381,Q5VTR2 7
Phosphorylation of emi1 0.4494820587471037 0.1049456160883069 0.9164189623864976 1.0 1.0 4 P06493,Q12834 2
Metabolism of folate and pterines 0.4608500306188724 0.1044775015427967 0.9167904217244168 1.0 1.0 9 Q9H2D1,P00374 2
Sulfur amino acid metabolism 0.4606118191149257 0.1039348753808589 0.9172210304227876 1.0 1.0 9 Q9UBX3 1
Chaperone mediated autophagy 0.4559754672862287 0.1029125856899559 0.918032348804092 1.0 1.0 7 P13473 1
Regulation of innate immune responses to cytosolic dna 0.4433164128595624 0.0978925686662615 0.9220176009900234 1.0 1.0 3 Q9UJV9,P19474 2
Maturation of sars cov 2 spike protein 0.4576789514930726 0.0843156787155417 0.9328054469783236 1.0 1.0 12 P27824,P46977,P04843,P04844,P26572,Q16706,P14314 7
Mitotic telophase cytokinesis 0.4588077779639195 0.0827739112302798 0.9340313137452432 1.0 1.0 13 Q14683,Q8WVM7,Q9UQE7 3
Ra biosynthesis pathway 0.4345741680767115 0.0807355898217142 0.9356522326052452 1.0 1.0 3 Q9HBH5,Q8NBN7 2
Translation of replicase and assembly of the replication transcription complex 0.4371375871708115 0.0800018369143465 0.9362357950091058 1.0 1.0 4 Q9Y3E7,Q9UQN3 2
Aflatoxin activation and detoxification 0.4330589750686399 0.0723130955895198 0.9423527432081134 1.0 1.0 4 Q9UJ14,Q99735 2
Collagen formation 0.452213109836908 0.0683307647697135 0.9455223346087984 1.0 1.0 13 O75718,P13674,Q32P28,O60568 4
Unblocking of nmda receptors glutamate binding and activation 0.4301474571058027 0.0669920534184195 0.946588029443101 1.0 1.0 4 P07196 1
Long term potentiation 0.4301474571058027 0.0669920534184195 0.946588029443101 1.0 1.0 4 P07196 1
Ras activation upon ca2 influx through nmda receptor 0.4301474571058027 0.0669920534184195 0.946588029443101 1.0 1.0 4 P07196 1
Dag and ip3 signaling 0.4415785291092575 0.0637051038348471 0.949205040731904 1.0 1.0 9 P52292 1
Cytosolic sulfonation of small molecules 0.4304943591987456 0.0622206278780328 0.9503871356439522 1.0 1.0 5 Q8TB61 1
Ubiquinol biosynthesis 0.4243666926265332 0.0568393867908918 0.9546731385157132 1.0 1.0 4 O75208 1
Regulation of cytoskeletal remodeling and cell spreading by ipp complex components 0.4161263039188226 0.0540539148677228 0.9568922091395282 1.0 1.0 2 P12814 1
Abc family proteins mediated transport 0.4422652943378149 0.0529748824288617 0.957751920522887 1.0 1.0 58 Q9NP58,P28074,P49721,Q99436,O75027,P28070,Q99758,P08183,P20618,O15439,P33527,P33897,P40855,Q13438,O00231,Q9UBV2,P60900,Q9GZP9,Q9BUN8,O43242,P61289,P28072 22
Amyloid fiber formation 0.4329672969115714 0.0520465964845101 0.95849156507638 1.0 1.0 8 Q9Y287,Q92542,P05067 3
Synthesis of bile acids and bile salts via 7alpha hydroxycholesterol 0.4205923836389145 0.0505048992230695 0.9597200453736106 1.0 1.0 4 O14975,P22307,P51659 3
Signaling by flt3 fusion proteins 0.4261730666436935 0.0493832001720636 0.9606139161467188 1.0 1.0 6 Q15643,Q01082 2
Rac3 gtpase cycle 0.4649076755117416 0.0490433485176799 0.9608847503617776 1.0 1.0 34 O15173,Q15758,P42167,Q14739,P50402,Q6IAA8,P42166,Q8TAA9,Q13017,P02786,Q68EM7,Q13177,O15498,Q7L576,Q9UQB8 15
Rnd2 gtpase cycle 0.4487743144444641 0.0425611020571477 0.9660514034366794 1.0 1.0 18 Q07065,Q15058,Q8TAA9,Q13017,P02786,P51648 6
Apex1 independent resolution of ap sites via the single nucleotide replacement pathway 0.408911449520589 0.0375626914992654 0.9700363547859698 1.0 1.0 3 P18887,Q96T60 2
Runx3 regulates p14 arf 0.4034395263603078 0.0349301646677265 0.9721354273575362 1.0 1.0 2 P25440 1
Diseases associated with glycosylation precursor biosynthesis 0.42044760345484 0.0306995369397265 0.9755091604582472 1.0 1.0 8 P16278 1
Respiratory electron transport 0.4390827166306805 0.0254926062332783 0.9796620459434722 1.0 1.0 56 P13073,Q86Y39,P03886,P00403,Q16134,O43676,Q9Y6M9,P21912,O14949,Q8N8Q8,P20674,Q9NPL8,P22695,Q9P0J0,O95139,Q9UDW1 16
Lysosome vesicle biogenesis 0.4304500166523112 0.0144905460395101 0.9884386216407391 1.0 1.0 16 P15586,P05067,O14964,P20645,P09496,Q9BXS5,P50570,P51809 8
Cd28 dependent pi3k akt signaling 0.3896995123669166 0.0120341461658997 0.990398372324708 1.0 1.0 3 P31751 1
Disorders of transmembrane transporters 0.3687965168405431 0.0113873216999951 0.9909144281831112 1.0 1.0 80 Q9NP58,P28074,Q9BTX1,P49721,Q99436,P35613,O00400,O14678,P08195,P28070,Q99758,Q8N1F7,P53985,P20618,Q8NFH4,P33897,Q13438,O00231,Q9UBV2,P60900,Q9GZP9,Q9BUN8,O43242,P61289,P28072 25
Inactivation of cdc42 and rac1 0.3886068809926744 0.0107486919309025 0.9914239497979292 1.0 1.0 3 O94813,P63000 2
Alpha linolenic omega3 and linoleic omega6 acid metabolism 0.4093157959524402 0.0095403610281819 0.992388008703294 1.0 1.0 9 Q15067,O60427,P33897 3
Dcc mediated attractive signaling 0.3887165021156419 0.0059912455244642 0.9952197062941932 1.0 1.0 4 Q05397,Q14185,P63000 3
Phase i functionalization of compounds 0.4184876877090754 0.0024621350832404 0.9980355024153048 1.0 1.0 14 O43169,Q16850 2
Platelet homeostasis 0.4129045022663084 0.0021023327982426 0.9983225823542554 1.0 1.0 12 P23634,Q13586,P16615 3
Initiation of nuclear envelope ne reformation 0.4246135335926925 0.0008858169671312 0.9992932204106604 1.0 1.0 17 P50402,Q14739,P42167,Q86XL3 4