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Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
Regulation of innate immune responses to cytosolic dna 0.8531500332219574 1.8881214946587332 0.0590096418527865 1.0 1.0 5 P19474 1
Bmal1 clock npas2 activates circadian gene expression 0.9149520773311076 1.838354899220492 0.0660101263310666 1.0 1.0 3 P43490 1
Maturation of sars cov 2 nucleoprotein 0.7673491434327737 1.8236805359549275 0.0682003831158493 1.0 1.0 6 Q96SB4,P49841,P78362 3
Sting mediated induction of host immune responses 0.7388060974553199 1.8141071182683728 0.0696612358825925 1.0 1.0 7 P19474 1
Interleukin 37 signaling 0.8218868344091096 1.76847608105138 0.0769813474428671 1.0 1.0 5 P43378 1
Polo like kinase mediated events 0.7240790881450923 1.7508581512302792 0.079970346904691 1.0 1.0 7 Q5TKA1,P49454,P14635 3
Antimicrobial peptides 0.892194323144107 1.7497166371470727 0.0801672214266857 1.0 1.0 3 P35030,P81605 2
Sumoylation of transcription factors 0.7048987139598093 1.6680550471453657 0.0953047997396483 1.0 1.0 7 O75928,P42771 2
Met activates ras signaling 0.7298592876756017 1.6672256198332034 0.0954695502110611 1.0 1.0 6 Q96S59,Q9NWH9 2
Keratinization 0.7023253948175813 1.6569118568028784 0.0975372968484458 1.0 1.0 7 P15924 1
Formation of the cornified envelope 0.7023253948175813 1.6569118568028784 0.0975372968484458 1.0 1.0 7 P15924 1
Jnk c jun kinases phosphorylation and activation mediated by activated human tak1 0.7807807807807872 1.540721370083812 0.1233846134543741 1.0 1.0 4 O14733,O43318,P61088 3
Cohesin loading onto chromatin 0.6758370798227568 1.5025171520182072 0.1329636016676691 1.0 1.0 9 Q6KC79,Q14683,Q9Y6X3,Q8N3U4,Q9NTI5,O60216 6
Formation of senescence associated heterochromatin foci sahf 0.6680147055870416 1.4685576834491008 0.1419527996729499 1.0 1.0 9 Q9Y6J0 1
Activation of smo 0.8190502183406152 1.4617256369875475 0.1438164089746467 1.0 1.0 3 Q9Y496,P32121 2
Condensation of prometaphase chromosomes 0.6649504417263099 1.4552453111480874 0.1456013608844726 1.0 1.0 9 P67870,Q9BPX3,P19784,O95347,P14635,Q9NTJ3 6
Nod1 2 signaling pathway 0.6629268301677249 1.44645138679735 0.1480506377161536 1.0 1.0 9 O15111,Q13685,Q15750,O43318,P61088,Q14790 6
Wnt mediated activation of dvl 0.8032205240174701 1.398975018753949 0.161820474430034 1.0 1.0 3 O14641,P67870 2
Defects in biotin btn metabolism 0.6417628680118264 1.3929198835122136 0.1636440189868904 1.0 1.0 7 P50747,P05165,P11498 3
Establishment of sister chromatid cohesion 0.6404591689347208 1.387212367850887 0.1653770152237768 1.0 1.0 7 Q14683,Q8N3U4,Q9NTI5,O60216 4
Mismatch repair 0.6613737595051039 1.3824473218813775 0.1668343945640074 1.0 1.0 12 Q9UQ84 1
Activated tak1 mediates p38 mapk activation 0.740263956913484 1.380370426149793 0.1674726210366564 1.0 1.0 4 O43318,P61088 2
Resolution of d loop structures 0.6413533367255364 1.333614293287824 0.1823302961868367 1.0 1.0 10 Q9UQ84 1
Resolution of d loop structures through synthesis dependent strand annealing sdsa 0.6413533367255364 1.333614293287824 0.1823302961868367 1.0 1.0 10 Q9UQ84 1
Traf6 mediated induction of tak1 complex within tlr4 complex 0.7805676855895234 1.309080643671293 0.1905070351969473 1.0 1.0 3 O43318,Q6SZW1 2
Ikk complex recruitment mediated by rip1 0.7207780846897576 1.3030286432835392 0.192564982885639 1.0 1.0 4 O15111,P61088 2
Glycogen synthesis 0.7007634428549407 1.2962986580141775 0.1948726107544789 1.0 1.0 5 Q96G03,P46976,P13807 3
Activation of nima kinases nek9 nek6 nek7 0.7156178901713373 1.282541026896184 0.1996529225247865 1.0 1.0 4 P14635,P53350 2
Sumoylation of intracellular receptors 0.7735143060850812 1.281088225182357 0.200162679209797 1.0 1.0 3 O75928 1
Interconversion of nucleotide di and triphosphates 0.6695311124420902 1.271291807596567 0.2036248557480497 1.0 1.0 20 Q9H773 1
Glutathione synthesis and recycling 0.6341674202927251 1.2620719158504874 0.2069229098064147 1.0 1.0 6 O75223 1
Diseases of dna repair 0.6385979460668997 1.2475597368347406 0.2121923310685987 1.0 1.0 14 Q9UQ84,P20585 2
Ncam signaling for neurite out growth 0.6094990558665162 1.2327620637252017 0.2176645488164514 1.0 1.0 8 P28482,O15020,Q13813,P62993,Q01082,P06241 6
Mitotic telophase cytokinesis 0.6227361195507667 1.2159758259416813 0.2239941309565447 1.0 1.0 12 Q6KC79,Q14683,Q9Y6X3,P53350,Q8N3U4,Q9NTI5,O60216 7
Apoptosis induced dna fragmentation 0.6127372003332408 1.2095791775036382 0.2264404121406316 1.0 1.0 10 P09429,O76075 2
Vxpx cargo targeting to cilium 0.6073055324912056 1.2045492326733405 0.2283773651941527 1.0 1.0 9 Q96A65,Q8TAG9,Q8IYI6,Q92538,P18085 5
Met activates ptk2 signaling 0.6953459934972427 1.202091223097498 0.2293281865162053 1.0 1.0 4 P07942 1
Phosphorylation of emi1 0.7491812227074276 1.1846158904479365 0.2361693513294656 1.0 1.0 3 P14635,P53350 2
Transcriptional activation of mitochondrial biogenesis 0.6235915762464319 1.1834458643367831 0.2366324895100469 1.0 1.0 14 P48735,Q8WVM0 2
Activation of irf3 irf7 mediated by tbk1 ikk epsilon 0.7468801849580485 1.1755067675770123 0.2397920312410644 1.0 1.0 3 Q9UHD2 1
Interaction between l1 and ankyrins 0.6855036855036887 1.163083449375918 0.2447956464374416 1.0 1.0 4 Q01082,O15020,Q13813 3
Adherens junctions interactions 0.5839411368559472 1.121599356847608 0.262032825234316 1.0 1.0 8 P14923,P55196,Q9BY67,P35221 4
G0 and early g1 0.5775249478592821 1.1120754925714338 0.2661056929234031 1.0 1.0 7 Q5TKA1,P12004,P06493,P11388 4
Dap12 signaling 0.5752428204530862 1.1021556187602102 0.2703940227809402 1.0 1.0 7 P29353,O00459,P06241,P19174 4
Disassembly of the destruction complex and recruitment of axin to the membrane 0.5824531403368685 1.096978102756867 0.2726509644328208 1.0 1.0 9 O14641,Q14738,P49841,Q13362,P48729 5
Raf independent mapk1 3 activation 0.566629970200246 1.0647893660240386 0.2869712583868784 1.0 1.0 7 P28482,P27361,Q02750,P06493,P36507 5
Small interfering rna sirna biogenesis 0.6595619628432241 1.0606076688792223 0.2888682359280023 1.0 1.0 4 Q9UPY3,Q99598 2
Translesion synthesis by polk 0.5770547108492992 1.0558707870024762 0.2910272522575421 1.0 1.0 10 P35251,P41440,P35244,P12004,P15927,P40938 6
Biotin transport and metabolism 0.5726810064305887 1.0549124953892444 0.2914653469251682 1.0 1.0 9 P50747,O00763,P05165,P11498 4
Met promotes cell motility 0.5684026512341104 1.036550546838006 0.2999453707911104 1.0 1.0 9 P46108,P07942 2
Signaling by pdgfr in disease 0.5599553810425092 1.0359212090045602 0.3002389021446232 1.0 1.0 7 O43815,O00459,Q6UN15,P42224 4
Dna damage reversal 0.5801693526358889 1.033602110894612 0.3013222121577961 1.0 1.0 6 Q8N3C0,Q6P6C2,Q8N9N2,P16455,Q9H1I8 5
Regulation of tp53 expression and degradation 0.5800688013052415 1.0335600925042785 0.3013418640000638 1.0 1.0 12 Q9UER7,Q13362 2
Platelet sensitization by ldl 0.5581015689220837 1.0279188569959925 0.3039879985136928 1.0 1.0 7 Q14738,Q13362 2
Beta catenin phosphorylation cascade 0.5602155229277177 1.0191754138248983 0.3081196966666422 1.0 1.0 8 P48729,Q14738,P49841,Q13362 4
Signaling by ctnnb1 phospho site mutants 0.5602155229277177 1.0191754138248983 0.3081196966666422 1.0 1.0 8 P48729,Q14738,P49841,Q13362 4
Cell cell junction organization 0.5702368347820225 1.009248251867524 0.3128555909540165 1.0 1.0 11 P14923,Q8TEW0,P55196,P35221,Q9BY67 5
Signaling by alk 0.5528380099903031 1.0052379487577632 0.3147822860555034 1.0 1.0 7 Q96ST3,P19174,O00459,P29353,Q13547 5
Synthesis of udp n acetyl glucosamine 0.6261605679956245 1.004515127986017 0.3151303831733378 1.0 1.0 5 Q9UJ70,O94808,O95394,Q06210 4
Processing and activation of sumo 0.6420530872101909 0.9918805896689832 0.3212557787657455 1.0 1.0 4 Q9P0U3 1
Synthesis of pips at the late endosome membrane 0.6418188970750024 0.9909645119931424 0.3217029092529251 1.0 1.0 4 O00443,Q08AM6 2
Myoclonic epilepsy of lafora 0.8761255115961768 0.9875222364258736 0.3233866873989641 1.0 1.0 2 P46976 1
Uptake and function of anthrax toxins 0.639809720598175 0.9831091270893494 0.3255537327130842 1.0 1.0 4 O14733,Q02750 2
Constitutive signaling by aberrant pi3k in cancer 0.5517398264155707 0.9828597035034838 0.3256764928157563 1.0 1.0 8 P84095,O00459,P62993,P06241,Q9NWH9,O43815 6
Uptake and actions of bacterial toxins 0.5506023791976923 0.977999550956067 0.328074546175221 1.0 1.0 8 Q16881,Q02750 2
Receptor mediated mitophagy 0.6381097452061582 0.9764681904515778 0.3288325037861472 1.0 1.0 4 P67870 1
Apoptotic cleavage of cell adhesion proteins 0.564582344849655 0.9683991759392974 0.3328450508717862 1.0 1.0 6 P15924,Q07157 2
Ticam1 rip1 mediated ikk complex recruitment 0.6931601373172289 0.9643449097453924 0.3348730321365145 1.0 1.0 3 P61088 1
Irak1 recruits ikk complex 0.6931601373172289 0.9643449097453924 0.3348730321365145 1.0 1.0 3 P61088 1
Nephrin family interactions 0.5536464788956674 0.9562626677704458 0.3389395458803623 1.0 1.0 10 P46940,Q13813,O00459,Q9Y5K6,P12814,Q01082,P06241 7
Sema4d in semaphorin signaling 0.5482192371371221 0.9504892808174412 0.341863697951891 1.0 1.0 9 P35579,Q9NWH9,O75116 3
Signaling by wnt in cancer 0.5513697024921774 0.946649533859698 0.3438173942064817 1.0 1.0 10 Q14738,P49841,P56545,Q13362,P48729 5
Generation of second messenger molecules 0.6276089130331973 0.9355688510669627 0.3494952184848687 1.0 1.0 4 Q8N8S7,P19174 2
Ethanol oxidation 0.68423975428971 0.9297068512818756 0.3525228861809637 1.0 1.0 3 P30837 1
Pkmts methylate histone lysines 0.5826400623326605 0.927165478631934 0.3538406234854079 1.0 1.0 19 Q9H7B4,O15047,Q86TU7,Q6VMQ6 4
Hdr through single strand annealing ssa 0.5895329956158293 0.9232352511271612 0.3558846221326992 1.0 1.0 21 Q92547,Q9UQ84,Q9BX63,O60921,Q13535 5
Rna polymerase iii transcription initiation from type 1 promoter 0.5482481499069256 0.9166002733882732 0.3593521410657831 1.0 1.0 11 Q12789 1
Nef mediated downregulation of mhc class i complex cell surface expression 0.6026416179984989 0.9139225228439436 0.3607575579568129 1.0 1.0 5 P56377 1
Homologous dna pairing and strand exchange 0.5871218594106894 0.9135087085153336 0.3609750555804403 1.0 1.0 21 Q92547,Q9UQ84,Q9BX63,O60921,Q13535 5
Met receptor recycling 0.6014109768237641 0.9092146558261656 0.3632368295080757 1.0 1.0 5 P46108 1
Role of abl in robo slit signaling 0.6168585525572401 0.8939434153150412 0.3713521671269622 1.0 1.0 4 O94813,Q7Z460 2
Signaling by flt3 fusion proteins 0.5258070463352289 0.8899180716180378 0.3735098795164404 1.0 1.0 7 Q92614,Q01082,Q15643 3
Signal attenuation 0.615342615342614 0.8880960821221319 0.3744890699476393 1.0 1.0 4 P28482,P29353,P62993 3
Negative feedback regulation of mapk pathway 0.6153426153426137 0.8880960821221306 0.37448906994764 1.0 1.0 4 P28482,Q02750,P36507 3
Transcription of e2f targets under negative control by dream complex 0.5947569634079461 0.8838246177107019 0.3767908950590972 1.0 1.0 5 Q5TKA1,P12004,P11388,Q13547 4
Activation of ampk downstream of nmdars 0.5239519348191471 0.8820892880879775 0.3777285244712816 1.0 1.0 7 P54646,P04350 2
Signalling to ras 0.5933864465413421 0.8786093369984873 0.3796131314818862 1.0 1.0 5 P11233 1
Recycling of eif2 gdp 0.5216194659360014 0.8722641769007771 0.3830642756904248 1.0 1.0 7 P20042,Q13144,Q9NR50 3
Signaling by ntrk3 trkc 0.5407400767306481 0.8698385733237799 0.3843886282825548 1.0 1.0 6 Q8WX92,P29353,P62993,P19174 4
Vldlr internalisation and degradation 0.5203495978431096 0.8669238205277141 0.3859837509181938 1.0 1.0 7 O95782,P09496,Q96CW1,Q00610 4
Signaling by ntrk2 trkb 0.5230221752306096 0.8613543473034532 0.3890429116802194 1.0 1.0 8 P29353,P06241,P62993,P19174 4
Hats acetylate histones 0.6040390441648759 0.8587300674967596 0.3904894578633771 1.0 1.0 29 Q9NPF5,O75486,Q9H9T3,Q9UPT9,Q92794,Q8NEM7 6
Sema4d induced cell migration and growth cone collapse 0.5175706766420107 0.8552593779470061 0.3924075707447332 1.0 1.0 7 P35579,O75116 2
Mecp2 regulates transcription of neuronal ligands 0.6623908296943296 0.8456509160958765 0.3977475125624736 1.0 1.0 3 Q96ST3,P51608 2
Role of lat2 ntal lab on calcium mobilization 0.5841722289878103 0.8436830111156535 0.3988465634485076 1.0 1.0 5 P29353,O00459,P06241 3
Downstream signaling of activated fgfr1 0.5833716855799931 0.8406603998532411 0.4005382112089952 1.0 1.0 5 P29353,P62993,P19174 3
Downstream signaling of activated fgfr4 0.5833716855799931 0.8406603998532411 0.4005382112089952 1.0 1.0 5 P29353,P62993,P19174 3
Downstream signaling of activated fgfr3 0.5833716855799931 0.8406603998532411 0.4005382112089952 1.0 1.0 5 P29353,P62993,P19174 3
Downstream signaling of activated fgfr2 0.5833716855799931 0.8406603998532411 0.4005382112089952 1.0 1.0 5 P29353,P62993,P19174 3
Crmps in sema3a signaling 0.5179236654233812 0.8400909706105111 0.4008573823744932 1.0 1.0 8 Q14195,P49841,P06241,Q16555 4
Hdms demethylate histones 0.5254865382276861 0.8385911791171242 0.4016987622665739 1.0 1.0 10 O60341,Q9Y2K7,P41229,Q7LBC6,Q8IUF8 5
Translesion synthesis by polh 0.5365079565122348 0.8353709491122744 0.403508881384649 1.0 1.0 13 Q8TAT6,P35251,P41440,P35244,P12004,P15927,P40938 7
Tie2 signaling 0.5816085036680987 0.8340101740483774 0.404275250688511 1.0 1.0 5 P29353,O00459,P62993 3
Wnt5a dependent internalization of fzd2 fzd5 and ror2 0.516007289641456 0.8321270612860209 0.405337228546839 1.0 1.0 8 O95782,P09496,Q96CW1,Q00610 4
Type i hemidesmosome assembly 0.8316507503410653 0.8240475787501379 0.409912524178889 1.0 1.0 2 Q15149 1
Assembly of collagen fibrils and other multimeric structures 0.8316507503410653 0.8240475787501379 0.409912524178889 1.0 1.0 2 Q15149 1
Traf3 dependent irf activation pathway 0.656386462882103 0.82278065310767 0.4106327405723968 1.0 1.0 3 Q9UHD2,Q14258 2
Synthesis of pips at the early endosome membrane 0.5271855135935674 0.8146392891751337 0.415278814069236 1.0 1.0 6 Q08AM6 1
Oncogene induced senescence 0.5066112585846082 0.8095753185961932 0.4181842981747041 1.0 1.0 7 P28482,P42771,Q00534,P11802 4
Vitamin b2 riboflavin metabolism 0.8272851296043364 0.8083165117204885 0.4189083996233416 1.0 1.0 2 Q969G6 1
Regulation of bach1 activity 0.5940988020104621 0.8068339699769176 0.4197621450197872 1.0 1.0 4 Q9BX63 1
Mapk3 erk1 activation 0.5940485940485987 0.8066435752353587 0.4198718609340286 1.0 1.0 4 P06493,P27361,Q02750 3
Antigen activates b cell receptor bcr leading to generation of second messengers 0.5728913164264089 0.8012802064264126 0.4229694470915563 1.0 1.0 5 P06241,P62993,Q13586 3
Sumoylation of dna methylation proteins 0.5682317903229317 0.7838933812324096 0.433102673803867 1.0 1.0 5 Q9HC52 1
Rhobtb3 atpase cycle 0.5621779170281551 0.761425070929492 0.4464032175308285 1.0 1.0 5 Q15345,Q13618,P51151 3
Signaling by fgfr1 0.5002532069799298 0.7515422078801911 0.4523264090428944 1.0 1.0 9 P28482,P27361,P62993,P29353,P19174 5
Signaling by fgfr3 0.5002532069799298 0.7515422078801911 0.4523264090428944 1.0 1.0 9 P28482,P27361,P62993,P29353,P19174 5
Signaling by fgfr4 0.5002532069799298 0.7515422078801911 0.4523264090428944 1.0 1.0 9 P28482,P27361,P62993,P29353,P19174 5
Notch3 intracellular domain regulates transcription 0.5793246547686854 0.7512003414696018 0.4525320947474087 1.0 1.0 4 Q13573,Q15398 2
Dissolution of fibrin clot 0.6365608869811439 0.7481185684993251 0.4543886428336738 1.0 1.0 3 P35237 1
Assembly of the hiv virion 0.8095497953615294 0.7451232471960454 0.4561972166675412 1.0 1.0 2 Q99816 1
G2 m dna replication checkpoint 0.6356441048035002 0.7447010352751235 0.4564524731785893 1.0 1.0 3 P06493,P14635 2
Signaling by erbb2 ecd mutants 0.4901627396387039 0.7420979030686897 0.4580280202366338 1.0 1.0 7 P29353,P62993,P19174 3
Signaling by erbb2 in cancer 0.4901627396387039 0.7420979030686897 0.4580280202366338 1.0 1.0 7 P29353,P62993,P19174 3
Rho gtpases activate rocks 0.5052834996199125 0.7407597263660466 0.4588391382560364 1.0 1.0 11 P35579,O75116,O14974 3
Sumoylation of transcription cofactors 0.5260964732856956 0.732666886824739 0.4637616248837188 1.0 1.0 17 O75928,Q9UER7,Q14781,Q9HC52 4
Advanced glycosylation endproduct receptor signaling 0.4913013034615052 0.7310509143731451 0.4647480545860893 1.0 1.0 8 P52907 1
Rho gtpases activate paks 0.506635320012346 0.7309007264053968 0.4648397922890102 1.0 1.0 12 P35579,Q13177,Q14247,P60953,O14974 5
Synthesis of pips at the golgi membrane 0.4951062728419606 0.7308426796502786 0.4648752510632512 1.0 1.0 9 Q9UBF8,Q01968,Q08AM6 3
Neurexins and neuroligins 0.4900245968844053 0.7259178800277388 0.4678891146669102 1.0 1.0 8 Q15334,Q96HC4,O43491,O14936,Q14168,P11171,Q9UJU6 7
Rna polymerase i transcription termination 0.5041779057075895 0.7211969785646877 0.4707883304982807 1.0 1.0 12 P17480 1
Fceri mediated mapk activation 0.4996299423323267 0.7183115688997418 0.4725651984931285 1.0 1.0 11 P28482,P62993,Q13177,P29353,O14733,P19174 6
Nef mediates down modulation of cell surface receptors by recruiting them to clathrin adapters 0.4996215990111604 0.7182785830854211 0.4725855328586834 1.0 1.0 11 P56377,Q9BXS5 2
Cd28 dependent vav1 pathway 0.5009560229445421 0.7101104509072652 0.4776356459861197 1.0 1.0 6 Q16512,P62993,Q13177,P06241,P60953 5
Carboxyterminal post translational modifications of tubulin 0.4998911759440144 0.7059419932888183 0.4802242113596811 1.0 1.0 6 Q14166,P04350,Q9BUF5 3
Amyloid fiber formation 0.4806245519725145 0.7036652506574693 0.4816412655697011 1.0 1.0 7 Q9Y287 1
Metabolic disorders of biological oxidation enzymes 0.5457156681894205 0.701097634828954 0.4832420862737581 1.0 1.0 5 P48637,P22570 2
Rna polymerase iii transcription 0.4962350352289345 0.6900895028810776 0.4901379040082447 1.0 1.0 12 Q12789 1
Epha mediated growth cone collapse 0.4913808006873761 0.6859136552268761 0.4927675587139259 1.0 1.0 11 Q8N5V2,P35579,O75116 3
Carnitine metabolism 0.4942162861173064 0.6838389535732148 0.4940768659081458 1.0 1.0 6 P54646,O43772 2
Signaling by fgfr4 in disease 0.6188270086068942 0.6826395839310689 0.4948346148092759 1.0 1.0 3 P19174 1
Sema3a plexin repulsion signaling by inhibiting integrin adhesion 0.4933228998858584 0.6803769765372133 0.4962657953082434 1.0 1.0 6 O94887,Q9Y490 2
Shc mediated cascade fgfr4 0.6174099716601475 0.6774683264592215 0.4981088595897243 1.0 1.0 3 P29353 1
Activated ntrk3 signals through ras 0.6174099716601475 0.6774683264592215 0.4981088595897243 1.0 1.0 3 P29353 1
Activated ntrk2 signals through ras 0.6174099716601475 0.6774683264592215 0.4981088595897243 1.0 1.0 3 P29353 1
Shc1 events in egfr signaling 0.6174099716601475 0.6774683264592215 0.4981088595897243 1.0 1.0 3 P29353 1
Shc mediated cascade fgfr1 0.6174099716601475 0.6774683264592215 0.4981088595897243 1.0 1.0 3 P29353 1
Shc1 events in erbb4 signaling 0.6174099716601475 0.6774683264592215 0.4981088595897243 1.0 1.0 3 P29353 1
Shc mediated cascade fgfr3 0.6174099716601475 0.6774683264592215 0.4981088595897243 1.0 1.0 3 P29353 1
Shc related events triggered by igf1r 0.6174099716601475 0.6774683264592215 0.4981088595897243 1.0 1.0 3 P29353 1
Sensory processing of sound by outer hair cells of the cochlea 0.4959167704896826 0.6742861103023491 0.5001294328628836 1.0 1.0 13 P35579,P15311,Q13813,Q14651,Q12792,O14936,Q01082,P26038,P35241,O00159 10
Signaling by kit in disease 0.4713157810487287 0.6667211886496657 0.5049502418494738 1.0 1.0 7 O00459,P06241,P42224 3
Signaling by egfr in cancer 0.4687859640269213 0.656785120399837 0.5113190930659879 1.0 1.0 7 P29353,P07900,P62993,P19174 4
Constitutive signaling by ligand responsive egfr cancer variants 0.4687859640269213 0.656785120399837 0.5113190930659879 1.0 1.0 7 P29353,P07900,P62993,P19174 4
Constitutive signaling by egfrviii 0.4687859640269211 0.6567851203998363 0.5113190930659883 1.0 1.0 7 P29353,P07900,P62993,P19174 4
Inactivation of cdc42 and rac1 0.6105280296006727 0.6524933628355304 0.5140829531344029 1.0 1.0 3 O94813 1
Prc2 methylates histones and dna 0.4859203033489675 0.6518853835283434 0.514475114733099 1.0 1.0 6 Q09028,Q15910,P26358,Q15022 4
Golgi cisternae pericentriolar stack reorganization 0.4822557223422806 0.6506102948997441 0.5152980830493852 1.0 1.0 11 P28482,P53350,Q08379,P14635,P06493,Q9H8Y8,O60763 7
Tak1 activates nfkb by phosphorylation and activation of ikks complex 0.4705919221140235 0.64908949361365 0.5162805323952027 1.0 1.0 8 O15111,P09429,O43318,P61088 4
Inlb mediated entry of listeria monocytogenes into host cell 0.4663520507333483 0.6472698871558878 0.5174572870507346 1.0 1.0 7 O75886,Q9NWH9,O14964,P62993 4
Irak2 mediated activation of tak1 complex 0.7803547066848586 0.6440008367231302 0.519574891414408 1.0 1.0 2 O43318 1
Alpha protein kinase 1 signaling pathway 0.7803547066848586 0.6440008367231302 0.519574891414408 1.0 1.0 2 O43318 1
Ticam1 traf6 dependent induction of tak1 complex 0.7803547066848586 0.6440008367231302 0.519574891414408 1.0 1.0 2 O43318 1
Transcriptional regulation by e2f6 0.4832636744934053 0.6402052606717853 0.5220391631540036 1.0 1.0 12 O00311,P45973,Q9H9B1,Q15910,O14757 5
Met activates rap1 and rac1 0.4825971196028252 0.6392124034448329 0.5226847642421191 1.0 1.0 6 P46108,Q96N67,Q9NWH9 3
Cell junction organization 0.5090310394025083 0.626558346813749 0.5309487792254171 1.0 1.0 20 P14923,Q8TEW0,Q14315,Q03001,P55196,P35221,P12814,Q96AC1,Q15149,Q9BY67 10
Vitamin b5 pantothenate metabolism 0.4792494918330941 0.6265234658774168 0.5309716502849788 1.0 1.0 6 Q96CD2 1
Ercc6 csb and ehmt2 g9a positively regulate rrna expression 0.486156476460839 0.6232072047816097 0.5331483677602706 1.0 1.0 14 O95983,Q96KQ7,Q12873,P62805,Q13185,Q86YP4,Q92769,Q14839,Q09028,Q8WXI9,Q13547 11
Displacement of dna glycosylase by apex1 0.6022707154306651 0.622849399684113 0.5333834922057357 1.0 1.0 3 P27695 1
Signalling to erks 0.4821575509904177 0.6220485058039588 0.5339099734648349 1.0 1.0 13 P28482,Q02750,P46108,P62993,P11233,P29353,P36507 7
Fceri mediated ca 2 mobilization 0.4779732314642997 0.6217068648753212 0.5341346367982855 1.0 1.0 6 P29353,P62993,P19174 3
Hdr through homologous recombination hrr 0.5434537355093528 0.6213139498399913 0.5343930770269785 1.0 1.0 30 P35251,Q92547,Q9UQ84,P41440,Q9BX63,O60921,Q13535 7
Metabolism of rna 0.2495802313281225 0.6151456583747872 0.5384585313940298 1.0 1.0 486 P62847,Q969T7,Q6UN15,Q15459,Q05519,P61247,P08708,P35637,P52298,P67809,Q9BVL2,P51665,P46087,P46782,P28070,P49721,Q9UBP6,Q9H074,P23588,P24928,O43395,O75533,P52756,Q86TB9,Q9Y4Z0,P78346,Q96C86,Q92620,Q8TEQ6,Q96FX7,Q9NY93,Q9P2I0,Q86XP3,Q96QD9,O60306,O75832,Q7Z4G4,Q8WVM0,P51991,Q13868,P84098,P62314,Q9BVI4,Q9Y2L1,Q9BVJ6,Q7L014,Q8IYB3,O60832,Q9H2H8,Q969Y2,Q08170,P84103,Q9BUJ2,Q92917,P78316,P62910,P62829,Q52LJ0,Q13895,Q9C0J8,Q9H0S4,O75175,Q99436,Q96BP3,Q9HCS7,Q96PZ0,Q9Y3I0,O75152,P18077,Q92530,Q2NL82,Q9Y5S9,P04792,Q9UNQ2,P11940,Q9UBB9,Q9NV31,Q9H974,P19338,P39687,P62244,Q04637,Q13573,Q8WUA2,Q07020,Q8IZH2,Q99459,Q14692,Q15287,Q9Y3Y2,Q9H6R4,O00267,Q9Y3U8,Q16629,Q14103,O75400,Q9HCG8,P09661,O43290,O43709,P62841,P62899,P35268,Q99848,Q96GA3,Q8IX12,P25787,P46779,P19447,Q92499,Q9Y4W2,P51003,P26196,O60231,O15504,P35658,P42766,P62851,Q14690,Q13601,P62917,P62913,P62263,Q8TEM1,Q6PGP7,Q8IY37,Q9Y6V7,Q9Y2R4,P20618,Q9BZI7,Q9GZS3,Q9C0C2,Q9BZJ0,P40429,P18124,Q9UQ35,P39023,P83881,P12270,P13984,Q15008,P63173 142
Nucleotide salvage 0.4610095633777525 0.6122071614084295 0.5404007040452343 1.0 1.0 8 P00491,Q08623,P55263,Q9BZX2 4
Polymerase switching on the c strand of the telomere 0.489872252888793 0.6098129064745857 0.5419857508821682 1.0 1.0 16 P49642,P41440,Q8WVB6 3
Mitochondrial iron sulfur cluster biogenesis 0.5403920853682459 0.6092257550376361 0.5423748112435323 1.0 1.0 4 Q9H1K1,P22570 2
Nectin necl trans heterodimerization 0.7699863574351575 0.6091030212688803 0.5424561551193472 1.0 1.0 2 Q9BY67 1
Alk mutants bind tkis 0.4550927608793574 0.60384846899232 0.5459443916154809 1.0 1.0 7 O00291,Q9NR09,Q9HC35,Q00610,O43815 5
Gab1 signalosome 0.5938864628821039 0.5931367368634706 0.5530896464902304 1.0 1.0 3 P41240,P62993 2
Met activates ptpn11 0.5938864628821039 0.5931367368634706 0.5530896464902304 1.0 1.0 3 Q9NWH9,P62993 2
Mapk1 erk2 activation 0.5938864628821039 0.5931367368634706 0.5530896464902304 1.0 1.0 3 P28482,P36507 2
Molybdenum cofactor biosynthesis 0.5937195339466301 0.5925493272833763 0.5534827997601535 1.0 1.0 3 Q9NQX3 1
Apobec3g mediated resistance to hiv 1 infection 0.5929886595886409 0.5899794059945636 0.5552044563557137 1.0 1.0 3 P17096 1
Negative regulation of mapk pathway 0.482744156417096 0.5838758999581298 0.559303808555148 1.0 1.0 16 P10398,P28482,Q14738,Q02750,Q13362,Q16537,P36507,P53041 8
Mrna capping 0.482067326340489 0.5814354646778302 0.5609470011905806 1.0 1.0 16 P19447,P52298,P13984,O00267 4
Flt3 signaling in disease 0.4563062189291593 0.5805562175410646 0.5615395875147644 1.0 1.0 9 Q15643,Q92614,P62993,Q06124,Q01082,Q9UBW7 6
Traf6 mediated irf7 activation 0.5320788019199519 0.5799844405252905 0.5619251105300909 1.0 1.0 4 Q9UHD2,Q14258 2
Purine salvage 0.5095500846852707 0.5734482772865729 0.5663412103488366 1.0 1.0 5 Q16854,P00491,P55263 3
Downregulation of erbb4 signaling 0.7587994542974101 0.5721275405472463 0.5672355723354552 1.0 1.0 2 P46934 1
Constitutive signaling by overexpressed erbb2 0.4644431546212535 0.5714002886484962 0.5677283334755283 1.0 1.0 6 Q96RT1,P29353,P62993 3
Oas antiviral response 0.5870633187772998 0.5692651662047398 0.5691762024533624 1.0 1.0 3 P61221,P21333 2
Signaling by pdgfra transmembrane juxtamembrane and kinase domain mutants 0.5073428127784958 0.5659164670808446 0.5714505668158689 1.0 1.0 5 O00459,P62993,P42224 3
G1 s specific transcription 0.4627836260048396 0.5641027332209152 0.572684218051466 1.0 1.0 12 P04818 1
Signaling by met 0.5044236885750805 0.5597083926750285 0.5756783568367814 1.0 1.0 24 Q96S59,P07942 2
Pecam1 interactions 0.5242706517380856 0.5529278057658902 0.5803128464343783 1.0 1.0 4 P06241,P19174 2
Stat3 nuclear events downstream of alk signaling 0.5233415233415303 0.5497358631080177 0.5825005549828366 1.0 1.0 4 Q92769,Q96ST3,Q13547 3
Collagen formation 0.4593758928344525 0.5389446997822281 0.5899250127248115 1.0 1.0 13 Q32P28,Q15149,P13674,O15460 4
Wnt5a dependent internalization of fzd4 0.4519976235326993 0.5382647742982584 0.5903942667775541 1.0 1.0 11 O14641,P32121 2
Signaling by pdgf 0.4444945721424659 0.537242777052632 0.5910999264920307 1.0 1.0 9 P46108,O00459,P62993,P42224,P19174 5
Downstream signal transduction 0.4444945721424659 0.537242777052632 0.5910999264920307 1.0 1.0 9 P46108,O00459,P62993,P42224,P19174 5
Zbp1 dai mediated induction of type i ifns 0.454708184607078 0.5361281551233033 0.5918699827044338 1.0 1.0 6 Q9UHD2 1
Thrombin signalling through proteinase activated receptors pars 0.4368739258511385 0.5358949168814165 0.5920311777171188 1.0 1.0 7 P32121 1
Nf kb activation through fadd rip 1 pathway mediated by caspase 8 and 10 0.4978197385325869 0.5338141449390005 0.5934701264278472 1.0 1.0 5 O15111,Q14790,Q14258 3
Integrin signaling 0.4515933247308681 0.5250189952757013 0.5995699861233665 1.0 1.0 6 P46108,P29353,P41240,Q9Y490 4
Platelet aggregation plug formation 0.4515933247308681 0.5250189952757013 0.5995699861233665 1.0 1.0 6 P46108,P29353,P41240,Q9Y490 4
Signaling by csf3 g csf 0.4371631076511698 0.5238463113893028 0.6003854393970329 1.0 1.0 8 P29353,Q93034,P62993,P42224 4
E3 ubiquitin ligases ubiquitinate target proteins 0.4689208596940029 0.522605916735251 0.6012485222523372 1.0 1.0 17 Q5VTR2,P50542 2
Sensory processing of sound 0.4722357038139447 0.5218883722937155 0.601748054660362 1.0 1.0 18 P35579,P15311,P52907,P56545,Q01082,P26038,P35241 7
Dna replication initiation 0.4320328551205752 0.5183714669270377 0.6041991184998579 1.0 1.0 7 P49642 1
Dna damage telomere stress induced senescence 0.4675303539800689 0.5178446876669025 0.6045666364820488 1.0 1.0 17 Q9Y6J0 1
Dual incision in gg ner 0.4951426401168026 0.5168619999035674 0.6052524959914289 1.0 1.0 25 Q86WJ1,P35251,Q9UGN5,P19447,P41440,Q13620,Q07864,P35244,P09874,P12004,Q92889,P28340,P15927,P40938 14
Cyclin d associated events in g1 0.4414584140435268 0.513574899300581 0.6075492324673246 1.0 1.0 10 P63151,Q13309,P11802,P42771,Q00534 5
Prolonged erk activation events 0.4335598902982127 0.5109702101471756 0.6093719165672922 1.0 1.0 8 P28482,Q02750,P36507,P46108 4
Rho gtpases activate ktn1 0.4366787544775786 0.5093277241134443 0.6105225280764661 1.0 1.0 9 Q9H0B6,P84095,Q07866,P60953,Q9NSK0 5
Regulation of signaling by cbl 0.4291933160980468 0.5082052865664115 0.6113093838028707 1.0 1.0 7 P46108,O00459,P06241 3
Cell extracellular matrix interactions 0.4272932419752713 0.5014501987088835 0.6160543185657235 1.0 1.0 7 Q14315,P12814,Q96AC1,P21333 4
Diseases of immune system 0.5082242893892454 0.4986860577562503 0.6180005681735576 1.0 1.0 4 P09429 1
G alpha 12 13 signalling events 0.4429635576177189 0.494097522270752 0.6212373076493147 1.0 1.0 12 Q8N5V2,O75116,Q13464 3
Kinesins 0.4808050419901368 0.4925387513668999 0.6223385344230967 1.0 1.0 23 Q9NS87,Q9BUF5,Q9H0B6,O95239,O95235,O00139,Q96Q89,P52732,Q07866,Q9BVA1,P04350,O60333,Q9Y496,Q9NSK0,Q9BW19 15
Mtorc1 mediated signalling 0.4424238635160019 0.4922474263374979 0.6225444410402221 1.0 1.0 12 P23588,Q15382 2
Peroxisomal protein import 0.4907355197553522 0.4914567965818989 0.6231034017391894 1.0 1.0 26 O75874,P50542 2
Sumo is conjugated to e1 uba2 sae1 0.5641273535151339 0.4912858809131966 0.6232242645393788 1.0 1.0 3 Q9UBT2 1
Sumo is transferred from e1 to e2 ube2i ubc9 0.5641273535151339 0.4912858809131966 0.6232242645393788 1.0 1.0 3 Q9UBT2 1
Mastl facilitates mitotic progression 0.4847338580116179 0.4908169217708327 0.6235559405262379 1.0 1.0 5 P14635 1
Signaling by flt3 itd and tkd mutants 0.5615018262917255 0.4826023260922193 0.6293781271839194 1.0 1.0 3 P62993 1
Frs mediated fgfr1 signaling 0.5615018262917255 0.4826023260922193 0.6293781271839194 1.0 1.0 3 P62993 1
Frs mediated fgfr2 signaling 0.5615018262917255 0.4826023260922193 0.6293781271839194 1.0 1.0 3 P62993 1
Activated ntrk2 signals through frs2 and frs3 0.5615018262917255 0.4826023260922193 0.6293781271839194 1.0 1.0 3 P62993 1
Frs mediated fgfr3 signaling 0.5615018262917255 0.4826023260922193 0.6293781271839194 1.0 1.0 3 P62993 1
Frs mediated fgfr4 signaling 0.5615018262917255 0.4826023260922193 0.6293781271839194 1.0 1.0 3 P62993 1
Glycogen metabolism 0.4325346672777613 0.482533668384401 0.6294268869795938 1.0 1.0 10 P13807,P35573,Q93100,Q96G03,P46976 5
Cytosolic sensors of pathogen associated dna 0.4693242687936907 0.4776088594109369 0.6329286240360945 1.0 1.0 21 Q9UHD2,O15111,P19474,Q9BUI4 4
Ret signaling 0.4201894554348555 0.4765441951494261 0.6336867294052864 1.0 1.0 7 O00459,P62993,Q9NR12,P29353,P19174 5
Activation of rac1 0.5006825006825135 0.4738821212000688 0.6355839693040082 1.0 1.0 4 Q16512,Q13177,O94813 3
Interleukin 6 family signaling 0.4998634998634997 0.4712168184386393 0.6374859096017871 1.0 1.0 4 Q06124,P40763,P42224 3
Interleukin 6 signaling 0.4998634998634997 0.4712168184386393 0.6374859096017871 1.0 1.0 4 Q06124,P40763,P42224 3
Transport of connexons to the plasma membrane 0.4784973108059288 0.4708153254931707 0.6377726193962019 1.0 1.0 5 P04350,Q9BUF5 2
Gap junction assembly 0.4784973108059288 0.4708153254931707 0.6377726193962019 1.0 1.0 5 P04350,Q9BUF5 2
Infectious disease 0.2561162844717415 0.469443980385623 0.638752318030646 1.0 1.0 367 Q99720,P62847,Q96F07,Q13177,P61247,O95782,P56377,P08708,Q9UER7,P52298,Q9BVL2,P51665,P46782,Q63HN8,P17096,P28070,Q96SB4,P49721,Q15910,P24928,P19174,Q9UQB8,P49841,Q02750,Q13464,P63218,Q93034,Q99816,Q9UHD2,O14733,O75832,P48729,P29083,O75475,P84098,Q9HD42,Q8WXI9,Q9H9H4,P46108,Q9Y6G9,P04350,O75116,P00558,Q16881,Q15185,Q00403,P62910,P62829,P23193,Q99436,P18077,P78362,Q92530,Q14839,P46060,P50750,P62244,Q96FJ2,Q8WUW1,Q07020,O00267,Q9Y3U8,Q14185,Q9H3P2,Q9HBM6,P35579,P62841,Q12873,P62899,P52294,Q86YP4,P35268,P18858,P25787,P46779,P19447,Q9Y5B9,Q14241,Q16706,O15504,P35658,P42766,P62851,Q00610,P62917,P62913,P62263,Q9BXS5,Q9NWH9,Q8TEM1,O14641,Q9BRG1,P55199,P20618,Q9NZQ3,P40429,P18124,O95983,O60341,P39023,P83881,P09874,P12270,P13984,Q13618,Q13263,Q15008,P63173,P62424,P61160,P60953 111
Pcna dependent long patch base excision repair 0.4595591754338746 0.4682405564413546 0.6396125723999042 1.0 1.0 19 P18858,P35251,Q07864,P41440,P35244,P12004,P28340,P15927,P40938,P27695 10
Ctla4 inhibitory signaling 0.4236926223303676 0.4643834944078829 0.6423730134623324 1.0 1.0 9 Q16537,Q14738,Q13362 3
Negative regulation of fgfr1 signaling 0.4338283695088151 0.4634475612411381 0.6430435940467847 1.0 1.0 6 P28482,Q06124,P27361,P62993 4
Negative regulation of fgfr4 signaling 0.4338283695088151 0.4634475612411381 0.6430435940467847 1.0 1.0 6 P28482,Q06124,P27361,P62993 4
Negative regulation of fgfr3 signaling 0.4338283695088151 0.4634475612411381 0.6430435940467847 1.0 1.0 6 P28482,Q06124,P27361,P62993 4
Negative regulation of fgfr2 signaling 0.4338283695088151 0.4634475612411381 0.6430435940467847 1.0 1.0 6 P28482,Q06124,P27361,P62993 4
Spry regulation of fgf signaling 0.4338283695088151 0.4634475612411381 0.6430435940467847 1.0 1.0 6 P28482,Q06124,P27361,P62993 4
Metabolism of folate and pterines 0.4230103281808921 0.4620745854511875 0.6440278347190531 1.0 1.0 9 P41440,P34897,P34896 3
Repression of wnt target genes 0.4756993467675349 0.4619505400945439 0.6441167894963984 1.0 1.0 5 Q04727 1
Potential therapeutics for sars 0.5253819586239111 0.4554916348866773 0.6487555842810282 1.0 1.0 40 Q99720,Q12873,Q9UHD2,Q14839,O75116 5
Recognition of dna damage by pcna containing replication complex 0.4506508590308881 0.4506593890501716 0.6522350560803514 1.0 1.0 18 P35251,Q07864,P41440,Q13620,P35244,P12004,P28340,P15927,P40938 9
Termination of translesion dna synthesis 0.4502396839748163 0.4493521708682879 0.653177628375976 1.0 1.0 18 P35251,Q07864,P41440,P35244,Q14258,P12004,P28340,P15927,P40938 9
Processing of dna double strand break ends 0.503483527578091 0.4486287978528949 0.6536994560561515 1.0 1.0 34 Q92547,Q9UQ84,Q9BX63,P61088,O60921,Q13535 6
Rho gtpases activate iqgaps 0.4258407002676233 0.448261597126859 0.653964412574616 1.0 1.0 11 P46940,P35221,P04350,Q13576,P60953 5
Synthesis of active ubiquitin roles of e1 and e2 enzymes 0.4256464893119974 0.4476219735406668 0.6544260420504546 1.0 1.0 11 Q93008,P22314,Q16763,P45974,Q93009,P61086,P68036,P49427,P60604 9
Rna polymerase ii transcription 0.2766739839074276 0.4471515902418269 0.6547656116953158 1.0 1.0 348 Q9UQ84,Q6UN15,Q68E01,O60244,Q05519,Q9UER7,P52298,P51665,P46087,Q13362,P28070,Q15382,P49721,Q92925,Q9NP77,Q15910,Q92794,P24928,Q13535,P49841,Q93074,Q92620,Q9HC52,Q9P2I0,P51608,Q9BX63,Q96QD9,O75832,P42771,P29083,Q07157,Q92547,O15047,Q8N201,Q8WXI9,Q15648,Q5VT52,Q6PD62,Q9NYV4,Q8IYB3,P19784,P51530,Q16881,Q00403,Q13309,Q08170,P84103,Q9C0J8,Q9H1A4,P54646,P23193,P14635,O75175,Q99436,Q96HW7,O75152,Q92530,Q14839,O14965,Q9Y5S9,P50750,P15954,Q13573,Q9UBL3,Q15287,Q9Y3Y2,O00267,Q7KZ85,P45973,P67870,Q9H9B1,Q9H3P2,Q16629,Q9HBM6,O14757,Q12873,Q86YP4,P51532,P38398,Q96PK6,Q14781,Q96J02,O60921,O14497,Q9UJX6,P25787,Q9NVM9,Q9UHA4,P19447,Q9UPN9,P51003,Q16763,Q9Y5B9,Q14241,Q13472,Q9NWH9,O00311,P55199,P20618,Q9BZI7,Q92696,Q8WYQ5,P09874,P13984 104
Tnfr1 induced nfkappab signaling pathway 0.4097997123530937 0.4411616572151874 0.6590959692957425 1.0 1.0 7 O15111,O43318 2
The role of nef in hiv 1 replication and disease pathogenesis 0.4336037654837865 0.4398887111328463 0.6600177124561459 1.0 1.0 14 O95782,P56377,Q13177,P06241,Q9BXS5,Q10567 6
Runx1 interacts with co factors whose precise effect on runx1 targets is not known 0.4429910163688866 0.4371905881230334 0.6619731348726554 1.0 1.0 17 O14497,Q86U86,Q9HC52,P67870,Q92925,P51532,Q68CP9,P19784,Q14781 9
P130cas linkage to mapk signaling for integrins 0.7154160982264347 0.4364707655307928 0.6624952055060578 1.0 1.0 2 P46108 1
Base excision repair ap site formation 0.4661387220098281 0.4321912114259854 0.665602446360906 1.0 1.0 5 P78549,P29372,P62805,Q9NYB0 4
Rna polymerase i promoter escape 0.4345025421086532 0.4318687686761508 0.6658367948526098 1.0 1.0 15 P17480 1
Polymerase switching 0.4297258197097626 0.427529631821019 0.6689936071549876 1.0 1.0 14 P49642,P41440 2
Cell cycle 0.2910764637082592 0.4262357080018882 0.6699361004302651 1.0 1.0 330 Q9UQ84,O43683,Q9H3R5,Q86Y07,Q9Y248,P04818,O15078,O60763,Q9UER7,P51665,Q9BVL2,Q96RT8,Q5TKA1,Q7L590,Q13362,P28070,P49721,P41440,Q7Z460,P24928,Q13535,O43264,Q6KC79,P49454,P49841,Q07864,Q8WVB6,Q08379,Q8N3U4,Q9H900,Q9Y6D9,Q9BX63,O75832,P42771,Q14683,Q92547,P49642,P61088,Q15154,Q9Y6G9,P23258,P19784,P04350,O60832,Q8NF91,P51530,Q14738,Q9Y6X3,Q13309,Q9H1A4,P14635,Q99436,Q9NTI5,Q9Y266,Q92530,O14965,Q96FJ2,Q96EA4,Q99986,O14974,P67870,Q14980,Q96BD8,O60921,P18858,P25787,P35251,O15504,P35658,P53350,Q13472,Q14008,Q96T23,O00311,P50748,P20618,Q9NTJ3,P12270 78
Meiotic synapsis 0.4375621897386755 0.4202740734157421 0.6742852476455121 1.0 1.0 17 Q14683,Q8WXH0,P38398,Q13535,O94901,Q9UQE7,Q8N3U4,Q8NF91,O60216 9
Nef and signal transduction 0.542032006801848 0.4199515406040064 0.6745208548737316 1.0 1.0 3 Q13177 1
Dcc mediated attractive signaling 0.4588190783222798 0.4099892070970603 0.6818138648399279 1.0 1.0 5 Q14185,P60953 2
Nef mediated cd8 down regulation 0.4162821577053177 0.4059395467806208 0.684787019655313 1.0 1.0 6 P63010,O95782,Q96CW1 3
Nef mediated cd4 down regulation 0.4162821577053177 0.4059395467806208 0.684787019655313 1.0 1.0 6 P63010,O95782,Q96CW1 3
Rna polymerase i transcription initiation 0.4523660667490924 0.4047566363447438 0.6856564065224338 1.0 1.0 23 Q86YP4,P17480,Q12873,Q14839 4
Rhobtb1 gtpase cycle 0.4421152058585885 0.4037376063948994 0.6864056823432265 1.0 1.0 20 Q5VTR2,O75116,Q8IYB3 3
Transcriptional regulation of white adipocyte differentiation 0.4282609829294659 0.4021115888149055 0.6876019043494921 1.0 1.0 16 Q93074,O60244,Q15648 3
Regulation of runx1 expression and activity 0.5360262008733716 0.401287758048885 0.6882082756087939 1.0 1.0 3 Q06124,Q00534 2
Signaling by erythropoietin 0.4130444257605198 0.3957218138754703 0.692310261263225 1.0 1.0 6 P19174 1
Downregulation of tgf beta receptor signaling 0.4128139046416341 0.3949992344760336 0.6928434529336507 1.0 1.0 6 P62136 1
Insulin receptor signalling cascade 0.4023880653993955 0.394974640305547 0.6928616036630963 1.0 1.0 9 P28482,Q99570,P27361,O00459,P62993,P29353 6
Signaling by fgfr2 in disease 0.418814418948477 0.3937590781006255 0.6937589195455311 1.0 1.0 14 P52298,P24928,P13984 3
Netrin 1 signaling 0.4116734104570159 0.3924172851914083 0.6947499164545172 1.0 1.0 12 Q14185,P19174,P15311,P60953,O94813 5
Oxidative stress induced senescence 0.4308537171667958 0.3900228704970526 0.696519635291639 1.0 1.0 18 P28482,P27361,Q9HC52,Q15910,O14733,P11802,Q14781,P42771,Q00534,Q15022 10
Early phase of hiv life cycle 0.400586039867045 0.3893715191717066 0.6970013373792372 1.0 1.0 9 P18858,P17096,O75475 3
Glycogen breakdown glycogenolysis 0.3933695763484626 0.3879593093191972 0.6980461462015037 1.0 1.0 7 Q96G03,P46976,Q93100,P35573 4
Negative regulation of the pi3k akt network 0.4282156321014588 0.3823135551050615 0.702228801470504 1.0 1.0 18 P28482,Q14738,P27361,P84095,O00459,P62993,Q13362,P06241,Q9NWH9,Q16537,O43815 11
Telomere extension by telomerase 0.4011058174980987 0.3806498690650393 0.7034630718963415 1.0 1.0 10 Q9BUR4,Q9NPE3,Q5H9R7,O60832 4
Signaling by rho gtpases miro gtpases and rhobtb3 0.2155469439370749 0.3804002923788487 0.7036482976190448 1.0 1.0 290 Q07960,O43683,Q13492,Q9H3R5,Q96F07,Q13177,Q5VTR2,Q86Y07,O00308,Q8N5V2,P15924,Q13362,Q9H0B6,P41440,Q13017,P12814,Q7Z460,Q9UQB8,O43264,O15498,P49454,Q13464,Q03001,Q01968,Q9H2G2,Q9H900,Q9NQW6,Q9Y6D9,Q9HD26,Q9P2R3,Q9UDY2,Q9Y2I1,Q02952,Q9Y6G9,Q8IYB3,P35221,P04350,O75116,O00161,Q14738,Q96AC1,Q7Z6E9,Q9P0U3,Q9Y266,P80723,P46060,Q96FJ2,Q8WUW1,P14923,Q15345,Q96EA4,Q53HL2,Q9Y597,O14974,Q14185,Q9UEY8,Q9UNZ2,Q14247,P34897,P35579,P84095,Q96BD8,Q96C19,Q8WYP5,Q9NYL9,Q9NSV4,O60610,O43396,O94887,P46940,P53350,Q16513,Q14008,Q00610,Q96N67,O14641,P50748,Q9NZQ3,Q9H8V3,Q96T58,Q16537,Q9NSK0,P31948,O60341,Q9Y4F1,O60245,P60763,O00139,P41240,Q13618,Q01082,P61160,P60953 93
Mrna decay by 5 to 3 exoribonuclease 0.4004815169931802 0.3787548503269597 0.704869917876038 1.0 1.0 10 Q86TB9 1
Rna polymerase ii transcribes snrna genes 0.4774714332362559 0.3762783264311181 0.7067099903576282 1.0 1.0 34 Q9NVM9,Q00403,Q5VT52,Q68E01,P52298,P55199,Q9NP77,Q96HW7,Q8N201,P13984,P24928,P29083,P50750,O00267 14
Translesion synthesis by y family dna polymerases bypasses lesions on dna template 0.4346648041911923 0.3727457040379316 0.7093377169485295 1.0 1.0 21 Q8TAT6,P35251,Q07864,P41440,P35244,Q14258,P12004,P28340,P15927,P40938 10
Developmental biology 0.2639698776578171 0.371331368141538 0.7103907370567868 1.0 1.0 282 P62847,Q14195,Q13177,Q9Y490,Q96S59,O60244,P61247,P07942,Q8N5V2,P15924,O95782,P08708,P52298,P51665,P46782,Q8N8S7,P28070,Q01518,P46777,P38919,P49721,Q14919,Q15910,Q14574,Q7Z460,P24928,P19174,O94813,P49841,Q02750,Q93074,Q13464,O75928,Q13813,P06241,Q13200,Q12955,P62753,P61254,O00459,O75832,P35241,P84098,Q9BUF5,A0MZ66,Q15648,P36507,P28482,P05387,O95239,O15144,P48556,Q9NR12,P35221,P29353,P19784,P04350,O75116,P62750,P62277,P62910,P62829,Q99436,P18077,Q92530,Q9Y5S9,P11940,P62244,P14923,Q6ZW49,Q04637,Q13573,Q07020,Q9UBL3,Q15287,Q9Y3U8,Q14185,O15020,P67870,O60271,P35579,P62841,P62899,P51532,P35268,Q9Y2W1,P15311,P25787,P46779,P26038,O94887,P42766,P62851,Q00610,P62917,P62913,P62263,Q9NWH9,P20618,Q9BZI7,P40429,P18124,P39023,P83881,Q01082,Q15008,P63173,P62424,P61160,P60953,P46939 111
Fanconi anemia pathway 0.3946503842042047 0.3712292653934601 0.7104667773786582 1.0 1.0 9 P35244,Q9NVI1,Q9BXW9,Q92889,P15927,Q13535 6
Butyrate response factor 1 brf1 binds and destabilizes mrna 0.3975771660584195 0.370009702179061 0.7113752613508757 1.0 1.0 10 Q9Y2L1,Q13868,Q8IZH2 3
Scavenging by class f receptors 0.4668304668304782 0.368825400768778 0.7122578703436699 1.0 1.0 4 Q9Y4L1,P07900,Q92598 3
Rho gtpases activate cit 0.3969038777426593 0.3679991685902091 0.7128738541279087 1.0 1.0 10 O14974 1
Interleukin 7 signaling 0.5249739119156036 0.3678247678328822 0.7130038996932955 1.0 1.0 3 P51532 1
Chrebp activates metabolic gene expression 0.4443270481200003 0.3676257968216619 0.7131522767695542 1.0 1.0 5 O00763 1
Pyrimidine salvage 0.5248420338163053 0.3674326400237029 0.7132963284412652 1.0 1.0 3 Q9BZX2 1
Cell cycle mitotic 0.2654795396823333 0.3668083794600058 0.7137619567756526 1.0 1.0 278 P18858,P25787,P35251,Q9H900,Q9Y266,Q9Y6D9,O43683,Q9H3R5,Q92530,O14965,Q86Y07,Q9Y248,O75832,P04818,P42771,O15078,O60763,Q96FJ2,Q14683,O15504,P35658,P53350,P51665,Q9BVL2,Q14008,Q96EA4,Q96RT8,P49642,Q7L590,Q5TKA1,Q99986,Q13362,P28070,O14974,P49721,Q15154,O00311,P67870,Q9Y6G9,P41440,P50748,P20618,P23258,P19784,Q7Z460,P04350,P51530,Q9NTJ3,O43264,Q6KC79,Q14738,P49841,P49454,Q9Y6X3,Q13309,Q07864,Q14980,Q08379,Q96BD8,P12270,Q9H1A4,P14635,Q99436,Q8N3U4,Q9NTI5 65
Recognition and association of dna glycosylase with site containing an affected purine 0.4660114660114668 0.366423660367649 0.7140489671683876 1.0 1.0 4 P29372,P62805,Q9NYB0 3
Activated pkn1 stimulates transcription of ar androgen receptor regulated genes klk2 and klk3 0.4660114660114618 0.3664236603676338 0.7140489671683989 1.0 1.0 4 P62805,Q16512,O60341 3
Signaling by fgfr2 iiia tm 0.3995072496539844 0.3658813477620478 0.7144536151091141 1.0 1.0 11 P52298,P13984 2
Fgfr2 mutant receptor activation 0.3995072496539844 0.3658813477620478 0.7144536151091141 1.0 1.0 11 P52298,P13984 2
Collagen biosynthesis and modifying enzymes 0.3992617969537179 0.3651569861672663 0.7149942246085532 1.0 1.0 11 Q32P28,O15460 2
Interleukin 15 signaling 0.5231986899563413 0.3625608276714138 0.7169329768710186 1.0 1.0 3 P29353,P62993 2
Interleukin 20 family signaling 0.5231986899563402 0.3625608276714109 0.7169329768710209 1.0 1.0 3 Q06124,P42224 2
Map3k8 tpl2 dependent mapk1 3 activation 0.4414878619157996 0.359587106924119 0.7191559267043284 1.0 1.0 5 O15111 1
Dna damage bypass 0.43620809521261 0.3592152251739793 0.7194340876732532 1.0 1.0 23 P35251,P15927,P41440,Q13620,Q07864,P35244,Q14258,P12004,P28340,Q8TAT6,P40938 11
Regulation of tp53 activity through phosphorylation 0.481430071000763 0.3547744211220212 0.7227585924754105 1.0 1.0 38 Q92547,Q9UQ84,P67870,Q9HBM6,P54646,Q9BX63,Q9Y5B9,O60921,Q13535 9
Signaling by egfr 0.4106664181585574 0.3509166538374255 0.7256508770794157 1.0 1.0 16 Q13685,P41240,P62993,Q9Y6I3,P29353,Q06124,O14964,P19174,P60953 9
Lagging strand synthesis 0.4204241828810435 0.3424746822997404 0.7319936939272202 1.0 1.0 20 P18858,P49643,P35251,P51530,P49005,P41440,P35244,P49642,P27694,P12004,P28340,P15927,P40938 13
Ovarian tumor domain proteases 0.3774124081883568 0.3398317277611867 0.733983253054882 1.0 1.0 7 P06493,Q96FW1,Q14258 3
Degradation of the extracellular matrix 0.3896896802413864 0.3375785346395389 0.7356808203994631 1.0 1.0 11 P20810,P07942 2
Mecp2 regulates neuronal receptors and channels 0.3743513797955917 0.3310268905301107 0.7406241738356667 1.0 1.0 7 Q13547,Q96ST3,Q9NWH9,P51608 4
Processive synthesis on the lagging strand 0.3968940195091182 0.3307247883641343 0.7408523765864234 1.0 1.0 14 P18858,P49643,P49005,P35244,P49642,P27694,P12004,P28340,P15927,P51530 10
Amino acids regulate mtorc1 0.3992750587206857 0.3285087102677207 0.7425270595545046 1.0 1.0 15 Q15382 1
Signaling by moderate kinase activity braf mutants 0.4018962247245388 0.3269928891489183 0.7436732634861567 1.0 1.0 16 P10398,P28482,Q02750,P46940,P41240,Q9Y490,P18206,P32121,P36507 9
Costimulation by the cd28 family 0.4050412855794916 0.3269082057694074 0.7437373144881096 1.0 1.0 17 Q14738,O00459,P41240,Q13177,Q13362,P06241,Q16537,P60953 8
Processive synthesis on the c strand of the telomere 0.387933267487689 0.3237960397102096 0.7460924546688803 1.0 1.0 12 P18858,P49005,P35244,P27694,P12004,Q9NYB0,P28340,P15927,P51530 9
Integration of provirus 0.3707231839547812 0.3207758666540207 0.7483802493268081 1.0 1.0 7 P17096,O75475 2
Deadenylation of mrna 0.4041351086138481 0.3163134323783351 0.7517646166192784 1.0 1.0 18 P38919,Q04637,Q9H074,P23588,Q9C0C2,P11940,O75175 7
Telomere c strand lagging strand synthesis 0.4197067863230163 0.316292180494158 0.7517807458060424 1.0 1.0 23 P18858,P35251,P51530,P41440,Q8WVB6,P35244,P49642,P27694,P12004,Q9NYB0,P28340,P15927,P40938 13
Cell cell communication 0.4467410482953636 0.3152049016027079 0.752606084183308 1.0 1.0 32 Q13418,Q8TEW0,P14923,P46940,Q13813,Q14315,Q03001,Q92692,Q9Y5K6,P55196,P35221,P21333,P12814,Q96AC1,Q01082,P06241,Q15149,Q9BY67 18
Translation 0.1507888346892276 0.3130843306802603 0.7542165934022127 1.0 1.0 230 P62847,Q96GC5,P61247,P55884,Q13155,P08708,P49406,P46782,P26640,P54577,P60228,P46777,Q9BYN8,P23588,P49590,O76094,P43897,P20042,O75822,P49588,Q9NR50,Q96GW9,P82930,P62753,P61254,Q96A35,Q13084,Q7Z2W9,P49591,P84098,Q9HD33,P09132,P05387,Q14232,P62750,P62277,Q96E11,P62910,P62829,Q96RP9,Q9Y2Z4,Q9NWU5,Q9UBQ5,P18077,O15372,P11940,P37108,P62244,P56537,P09001,Q15031,Q04637,Q14152,Q07020,P62495,Q5T160,Q9Y3U8,Q9BYC9,Q9Y5N5,O75821,P62841,Q4U2R6,P62899,P35268,O60841,P46779,Q9P0M9,P42766,P62851,Q15046,Q13144,P62917,P62913,P62263,Q8TAE8,O43324,P40429,P18124,Q9P015,Q9Y3D9,P39023,P83881,P61009,P63173,P62424,P82912 86
Nervous system development 0.2848641632108313 0.3108663808924308 0.755902203208555 1.0 1.0 228 P62847,Q14195,Q13177,Q9Y490,Q96S59,P61247,P07942,Q8N5V2,O95782,P08708,P52298,P51665,P46782,Q8N8S7,P28070,Q01518,P46777,P38919,P49721,Q7Z460,P19174,O94813,P49841,Q02750,Q13464,Q13813,P06241,Q13200,Q12955,P62753,P61254,O00459,O75832,P35241,P84098,Q9BUF5,A0MZ66,P36507,P28482,P05387,O95239,O15144,P48556,Q9NR12,P29353,P19784,P04350,O75116,P62750,P62277,P62910,P62829,Q99436,P18077,Q92530,Q9Y5S9,P11940,P62244,Q04637,Q07020,Q15287,Q9Y3U8,Q14185,O15020,P67870,P35579,P62841,P62899,P51532,P35268,P15311,P25787,P46779,P26038,O94887,P42766,P62851,Q00610,P62917,P62913,P62263,Q9NWH9,P20618,Q9BZI7,P40429,P18124,P39023,P83881,Q01082,Q15008,P63173,P62424,P61160,P60953,P46939 95
Synthesis of diphthamide eef2 0.4459106875185031 0.3097909028729486 0.756719969985203 1.0 1.0 4 Q9H2P9,P13639 2
Deadenylation dependent mrna decay 0.4727207531594711 0.3071802737467373 0.7587061594238782 1.0 1.0 42 P38919,Q13868,Q969T7,Q04637,Q9H074,Q8IZH2,Q86TB9,Q9Y4Z0,P23588,Q9GZS3,Q9C0C2,P11940,Q06265,P26196,Q96C86,Q9Y2L1,O75175,Q6PGP7 18
G2 m dna damage checkpoint 0.46664988673019 0.3066251685469448 0.7591286941521709 1.0 1.0 40 Q92547,Q9UQ84,Q9BX63,P14635,P61088,O60921,Q13535 7
Phenylalanine metabolism 0.667667121418811 0.3046163820177336 0.7606583416093873 1.0 1.0 2 P61457 1
Adaptive immune system 0.2808328994585916 0.2942795773524728 0.7685442770038928 1.0 1.0 213 P19474,Q13177,O95487,O95782,P56377,P46934,P51665,Q63HN8,Q8N8S7,Q13362,P28070,P49721,Q9H0B6,P19174,Q13867,P06241,O94874,Q93034,P68036,Q13200,O00459,O43318,O75832,Q9BSL1,Q9BUF5,O94979,O43164,Q9UNE7,P61088,O95486,Q9UBG0,Q9UIQ6,P52907,Q9Y6G9,O95239,O94822,P48556,P52732,Q07866,Q15436,P09429,P04350,Q14203,Q10567,O00161,Q14738,Q13309,Q96CW1,Q9H1A4,Q6UWE0,Q9UJW0,Q7Z6E9,Q99436,Q9UJX4,O00232,Q92990,Q92530,Q96FJ2,Q13586,Q05086,Q13049,P61163,O94855,Q15345,Q14669,P62993,O15020,Q92692,Q8TBC4,Q15386,Q96J02,Q9UJX6,P25787,Q16763,Q00610,Q8NEZ5,Q9BXS5,Q9Y496,Q7Z6Z7,O15111,Q9ULT8,P20618,Q16537,Q9NSK0,O00139,P41240,Q5T4S7,Q13618,Q15008,P60953 90
M phase 0.25736573341377 0.2909720552165518 0.7710726919579087 1.0 1.0 210 P25787,Q9H900,Q9Y266,Q9Y6D9,O43683,Q9H3R5,Q92530,Q86Y07,O75832,O15078,O60763,Q96FJ2,Q14683,O15504,P35658,P53350,P51665,Q9BVL2,Q14008,Q96EA4,Q96RT8,Q99986,Q13362,P28070,P49721,Q15154,P67870,Q9Y6G9,P50748,P20618,P23258,P19784,Q7Z460,P04350,Q9NTJ3,O43264,Q6KC79,Q14738,P49454,Q9Y6X3,Q14980,Q08379,Q96BD8,P12270,Q9H1A4,P14635,Q99436,Q8N3U4,Q9NTI5 49
Mtor signalling 0.3889451937036011 0.2862152639958531 0.7747132535763546 1.0 1.0 17 P23588,P54646,Q15382 3
Signaling by fgfr1 in disease 0.3747961263287203 0.2816933100156473 0.7781786846830934 1.0 1.0 13 Q92614,O94905,O15164,Q16630 4
Ptk6 regulates rho gtpases ras gtpase and map kinases 0.4106321711952027 0.2782390981026232 0.7808288233936624 1.0 1.0 5 P46108 1
Metabolism of amino acids and derivatives 0.1644414355674246 0.2722882686911994 0.7854003758018226 1.0 1.0 193 P62847,P25787,P46779,P78540,P18077,Q92530,O43252,O75832,P61247,P49591,P62244,P52758,P08708,P36957,P84098,P42766,O14874,P62851,P51665,Q07020,P46782,Q15046,Q16762,P62917,P62913,P62263,P28070,P34896,Q9Y3U8,Q9UDR5,P49721,P20618,O43324,P40429,Q16881,P18124,P62841,P62899,P39023,P62910,P62829,P83881,Q96H78,P35268,Q15008,P63173,Q99436,P61457 48
Cytokine signaling in immune system 0.1810296445185048 0.2700965377176937 0.7870859856611367 1.0 1.0 191 P25787,Q9UHD2,P19474,O60573,Q92530,O14733,O43318,O75832,P43378,Q9H0E2,O15504,P35658,Q15750,P46934,Q04637,P51665,Q9BVL2,P28070,P61088,O15111,P49721,O43432,Q9Y3Z3,P52907,P46108,P20618,Q8TBC4,P29353,P11233,P09429,P09661,P19174,P04083,O15344,P29372,Q14738,Q02750,P78344,P52294,P51532,P12270,Q93034,Q99436,O75925 44
Rhov gtpase cycle 0.3786554790699023 0.2691026819131504 0.7878506666697542 1.0 1.0 16 O43396,P46940,Q13813,Q03001,Q00610,Q13177,Q01082,P60953 8
Processing of capped intron containing pre mrna 0.2130229495157725 0.2690011592518196 0.7879287905845134 1.0 1.0 190 Q6UN15,Q15459,Q9P2I0,Q86XP3,O75152,Q9Y5S9,O60306,Q96QD9,Q05519,Q9UBB9,P51991,O60231,O15504,P35658,P62314,P35637,P52298,P67809,Q9BVL2,Q13573,Q8WUA2,Q99459,Q15287,Q9Y3Y2,Q7L014,Q16629,Q8IYB3,Q14103,O75400,Q9BZI7,P09661,Q9HCG8,P24928,Q9H2H8,O43395,O75533,Q9UQ35,P52756,Q08170,P84103,Q9BUJ2,Q92917,Q9C0J8,Q9Y4Z0,P12270,P13984,Q92620,Q96BP3,Q9HCS7 49
Regulation of tp53 activity through acetylation 0.3806518993532567 0.2667822343007069 0.7896368336322896 1.0 1.0 17 Q12873,Q92794,Q14839 3
Methylation 0.3563119853974777 0.2666232826909208 0.789759227379099 1.0 1.0 9 Q9NZL9 1
Cyclin a b1 b2 associated events during g2 m transition 0.3623803591625824 0.2664996670465936 0.7898544157943699 1.0 1.0 11 P63151,P06493,P14635,P53350 4
Rna polymerase i transcription 0.4072505370917256 0.2606605490645486 0.7943542918072231 1.0 1.0 27 Q86YP4,P17480,Q12873,Q14839 4
Activation of the ap 1 family of transcription factors 0.4846871346506874 0.2566742607510978 0.7974302429466604 1.0 1.0 3 P28482 1
Free fatty acids regulate insulin secretion 0.4828083482811744 0.2519435439236595 0.8010847017295999 1.0 1.0 3 P29992 1
Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects 0.6455661664392942 0.2509964237418606 0.8018168741469185 1.0 1.0 2 Q00534 1
Rrna processing 0.2958037582855849 0.2460705432223374 0.8056276252015833 1.0 1.0 169 P62847,Q9NQZ2,Q9NXF1,P61247,P08708,P46782,P46087,Q06265,P46777,Q9NRX1,P78346,Q01780,Q9NY93,P62753,P61254,P56182,Q96EU6,Q8WVM0,Q13868,P84098,Q9NR30,Q9NPE3,Q9BVI4,Q9Y2L1,Q9BVJ6,P42285,P05387,O43818,O60832,P62750,P62277,P78316,P62910,P62829,Q13895,Q9H0S4,P18077,Q2NL82,P19338,Q9UNQ2,Q9NV31,O15213,P62244,Q07020,P61353,Q14692,Q9H6R4,Q9Y3U8,Q8IWA0,Q9Y2X3,Q9H4L4,Q9H0A0,O43709,P62841,P62899,P35268,Q99848,Q96GA3,P61313,P46779,Q9Y4W2,Q8TED0,Q68CQ4,Q14137,P42766,Q9Y5J1,P62851,Q9H9L3,Q14690,Q13601,P62917,P62913,P62263,Q8IY37,Q9Y6V7,O15091,P26373,Q9Y2R4,P62424,P40429,P50914,P18124,Q9BQ52,Q8IY81,P39023,P83881,P63173,Q9Y221 88
Diseases of signal transduction by growth factor receptors and second messengers 0.2051056588672468 0.2438934994001435 0.8073133039116895 1.0 1.0 167 P25787,Q6UN15,Q92614,Q92530,P51608,O00203,O43252,O75832,P26038,P48729,O94905,O43815,P46940,O94979,Q15643,P52298,P51665,Q13573,Q00610,Q63HN8,Q13362,P28070,Q9NWH9,P32121,O15111,P49721,O15164,P20618,P29353,P24928,P19174,P18206,Q16537,Q8IWJ2,O00291,P35579,Q14738,P49841,Q02750,P84095,Q16630,Q92734,P51114,P41240,P12270,P56545,P13984,Q01082,Q99436 49
Signaling by hippo 0.3405482023016608 0.2437228347339896 0.8074454870073227 1.0 1.0 7 O14641,Q07157 2
Fgfr1 mutant receptor activation 0.3521743399644973 0.2429991767132054 0.8080060352284122 1.0 1.0 11 Q92614,O15164,Q16630 3
Ca2 pathway 0.3427779577861833 0.2419672768012968 0.8088055192165438 1.0 1.0 8 P09471,P63218 2
Phosphorylation of the apc c 0.3574759266715797 0.2416630996386474 0.8090412243653935 1.0 1.0 13 Q9UJX6,P53350,Q9H1A4,Q16763,P14635 5
Diseases of mitotic cell cycle 0.3596073484165311 0.2399312590848378 0.8103835472856666 1.0 1.0 14 Q9UJX6,Q9UJX4,Q13309,Q9UER7,Q9H1A4,Q16763,Q00534 7
Signaling by alk in cancer 0.4239787359781839 0.2393814016302904 0.8108098501864156 1.0 1.0 37 Q9HC35,P62753,P51608,P26038,O43815,O94979,P62993,Q00610,Q63HN8,P28482,Q07866,Q9P2E9,P29353,Q14203,P19174,P18206,Q8IWJ2,O00291,P35579,Q9NR09,P10644,Q92734,P12270 23
Extension of telomeres 0.4101649496466739 0.2389555545602136 0.8111400467588501 1.0 1.0 32 P18858,P35251,P51530,Q5H9R7,P41440,Q8WVB6,P35244,P49642,P27694,Q9NPE3,P28340,P12004,Q9NYB0,O60832,Q9BUR4,P15927,P40938 17
Protein ubiquitination 0.3962024820428996 0.2387212048643148 0.8113217729638265 1.0 1.0 27 Q5VTR2,P50542 2
Pi metabolism 0.3899537216777251 0.2374809559724673 0.8122836916125349 1.0 1.0 25 O95248,Q01968,Q08AM6,Q96T51,Q9HAU0,Q9UBF8 6
Tristetraprolin ttp zfp36 binds and destabilizes mrna 0.3494769614737794 0.2370770412721446 0.8125970231005295 1.0 1.0 11 Q9Y2L1,Q13868,Q8IZH2 3
Circadian clock 0.3490990217309485 0.2362569990110916 0.8132332522895325 1.0 1.0 11 P43490 1
Synthesis of pips at the plasma membrane 0.3603409933531684 0.2353292833693409 0.8139531683885479 1.0 1.0 15 Q96T51,Q9HAU0,Q01968 3
Grb2 sos provides linkage to mapk signaling for integrins 0.6384720327421592 0.234875566576792 0.8143053141773458 1.0 1.0 2 Q9Y490 1
Met activates pi3k akt signaling 0.6384720327421434 0.2348755665767569 0.8143053141773731 1.0 1.0 2 Q9NWH9 1
Cell cycle checkpoints 0.3418860494913259 0.2330295018126466 0.8157384971675414 1.0 1.0 157 Q9UJX6,P25787,Q9H900,Q9UQ84,Q9Y6D9,Q9Y266,O43683,Q9H3R5,Q92530,Q16763,Q9BX63,O75832,P42771,P46060,Q96FJ2,Q92547,P53350,Q13472,P51665,Q14008,Q96EA4,Q7L590,Q53HL2,Q13362,P28070,P61088,P49721,O00311,Q9Y6G9,P50748,P20618,Q7Z460,Q13535,P51530,O14757,O43264,Q14738,P49454,Q96BD8,P38398,Q9H1A4,P14635,Q99436,Q8WYP5,O60921 45
Regulation of tp53 activity 0.4856613602759441 0.2306349026046061 0.8175984501475833 1.0 1.0 64 Q92547,Q12873,Q9UQ84,P67870,Q9UER7,Q86YP4,Q9HBM6,Q14839,P54646,Q9BX63,Q13362,Q92794,Q9Y5B9,P42771,O60921,Q13535 16
Regulation of pten localization 0.6365620736698436 0.2306285556943011 0.8176033813422197 1.0 1.0 2 P46934 1
Energy dependent regulation of mtor by lkb1 ampk 0.3403119007587717 0.2299606308942109 0.8181223619004394 1.0 1.0 9 Q15382 1
Map2k and mapk activation 0.3574661159689618 0.2294029676650098 0.8185557297996051 1.0 1.0 15 P10398,P28482,Q02750,P46940,Q9UHA4,P41240,Q9Y490,P18206,P32121,P36507 10
Signaling by fgfr in disease 0.3826146954850896 0.2288381774873885 0.8189946926610863 1.0 1.0 24 Q16630,P52298,Q92614,O15164,P13984,P24928,O94905 7
Signal transduction by l1 0.3425282501872336 0.2284435676344278 0.8193014226604356 1.0 1.0 10 P28482,P27361,Q02750,O14786,P67870,P19784,P36507 7
Endosomal sorting complex required for transport escrt 0.3498230530324648 0.2255369003596764 0.8215616223978253 1.0 1.0 13 Q99816,Q9BRG1,Q9UQN3,Q9NZZ3,O14964,Q9H9H4 6
Signaling by notch3 0.3406001844803283 0.224379506457606 0.8224620156531097 1.0 1.0 10 O00308,P67809,Q9Y6A5,Q15398 4
Mitotic metaphase and anaphase 0.3071533135041222 0.224352803609298 0.8224827918676256 1.0 1.0 149 Q9UJX6,P25787,Q9H900,Q9Y266,Q9Y6D9,O43683,Q9H3R5,Q92530,Q86Y07,Q16763,O75832,P06493,P46060,Q96FJ2,Q14683,P53350,P51665,Q9BVL2,Q14008,Q96EA4,Q99986,Q53HL2,Q13362,P28070,P49721,Q9Y6G9,P50748,P20618,Q7Z460,P04350,O43264,Q14738,P49454,Q96BD8,Q9H1A4,P14635,Q99436,Q8WYP5,Q8N3U4,Q9NTI5 40
Mrna splicing 0.22680788747333 0.2232684350203915 0.8233265924205986 1.0 1.0 148 Q6UN15,Q15459,Q9P2I0,Q86XP3,Q9Y5S9,O60306,Q05519,Q9UBB9,P51991,O60231,P62314,P35637,P52298,P67809,Q13573,Q8WUA2,Q99459,Q15287,Q7L014,Q16629,Q8IYB3,Q14103,O75400,Q9BZI7,Q9HCG8,P09661,P24928,Q9H2H8,O43395,O75533,Q9UQ35,P52756,Q08170,P84103,Q9BUJ2,Q92917,Q9C0J8,Q9Y4Z0,P13984,Q92620,Q96BP3,Q9HCS7 42
Notch3 activation and transmission of signal to the nucleus 0.3486110613127816 0.2225501353531026 0.8238856492877364 1.0 1.0 6 P67809,O00308 2
Glycogen storage diseases 0.4704953629231045 0.222016122921229 0.8243013322503732 1.0 1.0 3 P46976 1
Signaling by cytosolic fgfr1 fusion mutants 0.3364191399030358 0.2216988886538811 0.8245482953130405 1.0 1.0 9 O15164,Q16630 2
Hsf1 activation 0.3559674861390284 0.2207376758801503 0.8252966938501216 1.0 1.0 16 Q15185,Q02790,P35244,P27694,P04792,Q92598,P15927,O75190 8
Negative epigenetic regulation of rrna expression 0.3780711207293113 0.2204746703204811 0.8255014972049828 1.0 1.0 24 P32780,P26358,Q96ST3,P19447,P17480,Q9UHR5,O60264,Q13547 8
Sema3a pak dependent axon repulsion 0.3354403086947354 0.2196624748114597 0.8261340316127297 1.0 1.0 9 O14786,P08238,P07900,Q16512,Q13177,P06241 6
Transcriptional regulation by tp53 0.3031326966913196 0.2178587345887175 0.8275391798831568 1.0 1.0 143 Q9UQ84,P19447,Q14839,Q9BX63,Q9Y5B9,P42771,Q14241,Q92547,P15954,Q9UER7,Q13472,Q13362,Q15382,O00267,P67870,P55199,Q9NYV4,Q9HBM6,Q92794,Q13535,Q16881,Q92696,Q12873,Q86YP4,P54646,P23193,P14635,O75175,O60921 29
Hiv infection 0.2611948223905908 0.2178570338455019 0.8275405050560809 1.0 1.0 143 P18858,Q99816,P25787,P19447,O75832,Q9Y5B9,P29083,Q14241,O95782,P56377,O15504,P35658,P52298,P51665,Q9BVL2,P17096,P28070,Q9BXS5,O00267,P49721,P55199,Q9HBM6,P20618,P24928,Q00403,P12270,P13984,P23193,Q93034,Q99436 30
Initiation of nuclear envelope ne reformation 0.3580404585784261 0.2140426956522995 0.8305137623153278 1.0 1.0 18 Q86Y07,P14635 2
Deactivation of the beta catenin transactivating complex 0.3351797622173337 0.2132939656308525 0.8310976799952388 1.0 1.0 10 Q04727 1
Signaling by robo receptors 0.324009155164802 0.2124602754205483 0.8317479659316716 1.0 1.0 138 P62847,Q13200,P25787,P46779,P62753,P61254,P18077,Q92530,Q13177,Q9Y5S9,P11940,O75832,P61247,P62244,P08708,P84098,P42766,Q04637,P52298,P51665,Q07020,P46782,P62851,P62917,P62913,P62263,Q8N8S7,P28070,Q15287,Q01518,P46777,P38919,Q9Y3U8,P49721,P05387,P48556,P20618,Q9BZI7,Q7Z460,P62424,P40429,P62750,O94813,P18124,P62841,P62899,P39023,P62910,P62829,P83881,P35268,Q15008,P63173,Q99436,P60953 55
Thromboxane signalling through tp receptor 0.3808643053488065 0.2112034554835308 0.8327285144866243 1.0 1.0 5 P63218 1
Hiv transcription initiation 0.3537111865283208 0.2111476375048346 0.8327720687287996 1.0 1.0 17 Q00403,P19447,Q9HBM6,P13984,P29083 5
Rhobtb gtpase cycle 0.3881773245768731 0.2103132290535678 0.8334232108913813 1.0 1.0 30 Q8IYB3,Q5VTR2,P12814,Q96T58,O75116,Q7Z6E9 6
Rhof gtpase cycle 0.3640075950019387 0.2099550425198636 0.8337027617836594 1.0 1.0 21 Q9P0U3,Q9UEY8,Q07960,Q02952,Q9Y4F1,P80723,Q9NSV4,Q13017,P12814,O00161 10
Signaling by receptor tyrosine kinases 0.1811702024081364 0.209211594923879 0.834283061267739 1.0 1.0 135 Q96F07,O00459,Q13177,Q14839,Q8WX92,Q9Y6W5,Q9Y5K8,Q9Y6I3,Q96S59,P04792,Q8WUW1,P07942,O60610,P14923,O95782,Q99570,Q13685,P46934,P52298,P31483,Q9UNE7,Q00610,Q96N67,Q9NWH9,P38606,P36507,O75348,P28482,Q14185,P46108,P35221,P29353,P11233,P24928,O75116,P19174,Q9UQB8,Q13547,Q05655,O14757,Q14738,Q96ST3,Q02750,Q13464,P41240,P21283,P13984,P06241,Q93034,Q96J02,P60953 51
Homology directed repair 0.4343842312126503 0.2090177943658267 0.8344343475191707 1.0 1.0 49 P35251,Q9UGN5,Q9UQ84,Q9BX63,P49916,Q92547,P60510,Q13472,P61088,Q92889,P15927,P40938,Q92878,P41440,P28340,P51530,Q13535,Q9NXR7,O14757,Q07864,P35244,P38398,P09874,P12004,O60921 25
Signaling by ptk6 0.3413253856530061 0.2087705289975437 0.8346273788255472 1.0 1.0 13 O75525 1
Translocation of slc2a4 glut4 to the plasma membrane 0.4097511285791912 0.2082722503729163 0.8350163975433693 1.0 1.0 39 P35579,O60343,Q9UIQ6,Q96A65,Q8TAG9,Q8IYI6,P11233,P54646,P04350,Q9Y496 10
Response of eif2ak1 hri to heme deficiency 0.4639737991266482 0.2069391805017079 0.8360573571290582 1.0 1.0 3 P08243,P20042 2
Rho gtpase effectors 0.3565711978691879 0.2038867491222173 0.8384420002518775 1.0 1.0 130 Q9H900,Q9Y266,Q9Y6D9,O43683,Q96F07,Q9H3R5,Q13177,Q9NSV4,Q9Y6W5,Q8WUM0,P46060,Q96FJ2,Q9BZD4,Q8WUW1,O60610,Q99570,Q9BUF5,P46940,P53350,Q16513,Q14008,O60879,Q96EA4,Q53HL2,Q13362,Q9HD26,O14974,P28482,O14641,Q96EE3,Q9H0B6,Q9Y6G9,P50748,O15144,Q14247,P35221,Q07866,Q9NZQ3,Q7Z460,P04350,O75116,Q13576,Q9UQB8,Q16537,Q9NSK0,Q8WYP5,O43264,P35579,Q9H081,Q14738,P49454,O60341,P84095,Q13464,O00139,Q96BD8,P21333,O14777,P60953,P61160 60
Class i mhc mediated antigen processing presentation 0.3352461565026579 0.2027695925158841 0.8393151258515712 1.0 1.0 129 P25787,Q92990,P19474,Q92530,O75832,O95487,Q05086,O94855,P46934,O94979,O43164,P51665,Q63HN8,Q8NEZ5,P28070,P61088,O95486,Q9UBG0,O15111,P49721,Q9UIQ6,O94822,P20618,Q8TBC4,P09429,O00161,Q15386,Q13309,Q13867,Q9H1A4,Q93034,Q7Z6E9,Q99436,Q5T4S7 34
Dna repair 0.3110267169090976 0.201671274213969 0.840173721012546 1.0 1.0 128 P18858,P35251,Q9UQ84,Q9UGN5,P19447,Q13620,Q9H981,Q9BX63,O60306,Q8N9N2,Q5UIP0,P49916,Q9H1I8,Q92547,Q6ZW49,P60510,Q96T60,Q13472,P61088,Q92889,Q6P6C2,Q8TAT6,Q9H9Q2,P52701,Q92878,P41440,P55199,Q9NVI1,P24928,P28340,O00213,Q13535,Q9NXR7,P51530,O14757,P27695,Q86WJ1,P29372,Q07864,Q04323,P35244,P38398,P09874,Q14258,P12004,P23193,Q99627,P20585,Q9HCS7,O60921,O75925 51
Retrograde transport at the trans golgi network 0.3591720131351392 0.2015918053735797 0.8402358520715079 1.0 1.0 21 P82094,Q96MW5,Q8WTW3 3
Influenza infection 0.2136224829420343 0.199504302004804 0.8418682784825593 1.0 1.0 126 P62847,P46779,P62753,P61254,P18077,P61247,Q8WUM0,P62244,P08708,O15504,P19525,P84098,P35658,P42766,P62851,Q9BVL2,P46782,Q07020,Q00610,P62917,P62913,P62263,Q8TEM1,P49790,P46777,Q9Y3U8,Q96EE3,P05387,P24928,P40429,P62750,P18124,P62841,P62899,P52294,P62910,P62829,P39023,P83881,P09874,P35268,P13984,P12270,P63173,P62424 45
Hiv transcription elongation 0.3708342162459968 0.1991893156896742 0.8421146568078222 1.0 1.0 26 Q14241,P19447,P52298,P55199,P13984,P23193,P24928,Q9Y5B9,P50750,O00267 10
Regulation of expression of slits and robos 0.335286171974939 0.1973984003701547 0.8435157813137686 1.0 1.0 124 P62847,Q13200,P25787,P46779,P62753,P61254,P18077,Q92530,Q9Y5S9,P11940,O75832,P61247,P62244,P08708,P84098,P42766,Q04637,P52298,P51665,Q07020,P46782,P62851,P62917,P62913,P62263,P28070,Q15287,P46777,P38919,Q9Y3U8,P49721,P05387,P48556,P20618,Q9BZI7,P62424,P40429,P62750,O94813,P18124,P62841,P62899,P39023,P62910,P62829,P83881,P35268,Q15008,P63173,Q99436 50
Notch4 intracellular domain regulates transcription 0.4591844398012774 0.1962162628098688 0.8444408995931643 1.0 1.0 3 Q13573 1
Regulation of pten gene transcription 0.3688583078712909 0.1960905716142038 0.8445392757667007 1.0 1.0 26 O95983,Q12873,Q9HC52,Q9UHA4,Q86YP4,Q14839,Q15910,Q8WXI9,Q14781,Q15382 10
Runx1 regulates genes involved in megakaryocyte differentiation and platelet function 0.3288992609419559 0.1959411719697234 0.8446562112582552 1.0 1.0 11 O15047 1
Parasite infection 0.3688272742932565 0.1921602238217383 0.8476167020080339 1.0 1.0 27 P28482,Q14185,P35579,P46108,Q96F07,O15144,P62993,Q9NZQ3,Q9Y6W5,P06241,Q9UQB8,P61160,P60953,Q8WUW1 14
Dap12 interactions 0.3212699973943765 0.1920373503906872 0.847712948496061 1.0 1.0 9 O00459,P62993,P29353,P06241,P19174 5
Formation of the beta catenin tcf transactivating complex 0.329347062945432 0.1918477074040025 0.8478614998870819 1.0 1.0 12 Q04727 1
Intraflagellar transport 0.3358121270407094 0.1891132506848391 0.8500040563323126 1.0 1.0 15 Q15643,P04350,Q9Y496,Q8NCM8,Q96FJ2 5
Separation of sister chromatids 0.3641719581952172 0.1869205682869145 0.8517229122554535 1.0 1.0 114 Q9UJX6,Q13200,P25787,Q9H900,Q9Y266,Q9Y6D9,O43683,Q9H3R5,Q92530,Q16763,Q9UQE7,O75832,Q8WUM0,P46060,Q96FJ2,Q9BZD4,O60216,Q14683,P53350,P51665,Q14008,Q96EA4,Q53HL2,Q13362,P28070,P49721,Q96EE3,Q9Y6G9,P50748,P20618,Q7Z460,P04350,Q16537,Q8WYP5,O43264,Q9H081,Q14738,P49454,O00139,Q96BD8,Q9H1A4,Q15008,Q99436,O14777,Q8N3U4,Q9NTI5 46
Raf activation 0.3340804865447425 0.1862230635294639 0.8522698382177305 1.0 1.0 15 Q14738,Q02750,Q13362,Q16537,P36507 5
Runx2 regulates osteoblast differentiation 0.6150068212824052 0.185502054459963 0.8528352690057461 1.0 1.0 2 P28482 1
Hiv elongation arrest and recovery 0.3483773955913029 0.1842314535862793 0.8538318853846179 1.0 1.0 21 Q14241,P55199,P13984,P23193,P24928,Q9Y5B9,P50750,O00267 8
Polb dependent long patch base excision repair 0.3110854583618326 0.183507975321603 0.8543994616303503 1.0 1.0 7 P18858,P27695,P09874 3
Gap filling dna repair synthesis and ligation in gg ner 0.3420089022770637 0.1822890712775579 0.8553558748540708 1.0 1.0 19 P18858,P35251,Q07864,P41440,P35244,P40938,P12004,P28340,P15927,P49916 10
Signaling by type 1 insulin like growth factor 1 receptor igf1r 0.3129448557635146 0.1820147038673577 0.8555711866326348 1.0 1.0 8 Q99570,O00459,P29353,P62993 4
Resolution of ap sites via the multiple nucleotide patch replacement pathway 0.3517535900573874 0.1817423394221513 0.8557849372054391 1.0 1.0 23 P18858,P35251,Q9UGN5,Q07864,P41440,P35244,P09874,P12004,P28340,P15927,P40938,P27695 12
Resolution of sister chromatid cohesion 0.4448414641743431 0.1815988151154809 0.8558975787891812 1.0 1.0 68 O14777,Q9Y266,Q9H900,Q9Y6D9,O43683,Q9H3R5,Q9UQE7,P06493,Q8WUM0,P46060,Q96FJ2,Q9BZD4,O60216,Q14683,P53350,Q14008,Q96EA4,Q53HL2,Q13362,Q96EE3,Q9Y6G9,P50748,Q7Z460,P04350,Q16537,O43264,Q14738,Q9H081,P49454,O00139,Q96BD8,P14635,Q8WYP5,Q8N3U4,Q9NTI5 35
P75ntr negatively regulates cell cycle via sc1 0.6128240109140559 0.1812239887635479 0.8561917660336407 1.0 1.0 2 Q13547 1
Perk regulates gene expression 0.3247890217489648 0.1795974530785156 0.8574686043194999 1.0 1.0 13 P20042,Q9Y2L1,Q13868,Q06265 4
Programmed cell death 0.232906502858994 0.1790727703751244 0.8578805624834962 1.0 1.0 107 P15924,P49721,P25787,P26583,Q15149,P41440,P09429,P28070,Q99436,P42771,Q96FJ2,O76075,Q14790 13
Nuclear events stimulated by alk signaling in cancer 0.3212895711541855 0.1781599793891239 0.8585973386651928 1.0 1.0 12 P28482,P27361,Q9HC35,P62753,Q00610,P51608 6
Interleukin 1 family signaling 0.4175079632925522 0.1768239058160069 0.8596467108055681 1.0 1.0 55 O15111,P25787,P49721,Q02750,Q9UHD2,P51665,Q92530,P43378,P20618,P09429,O43318,P28070,O75832,P61088,Q99436,Q9H0E2 16
Positive epigenetic regulation of rrna expression 0.3672559939825173 0.1765563560445043 0.8598568782471765 1.0 1.0 31 Q9NY93,Q13185,Q92769,Q14839,Q9UIG0,Q9NR30,Q8WXI9,O00159,Q96KQ7,P62805,Q09028,Q9BQG0,Q13547,O95983,Q12873,P49841,O75533,Q86YP4,O60264 19
Egfr downregulation 0.3121035560911142 0.1760191716360701 0.8602788808105362 1.0 1.0 9 P60953,O14964,P62993,Q9Y6I3 4
Chromatin modifying enzymes 0.4500646713924117 0.1759864062288793 0.8603046220268911 1.0 1.0 85 O14497,Q86TU7,Q12873,Q9H7B4,O15047,Q92925,O75486,Q9NPF5,Q86YP4,Q14839,Q6VMQ6,Q9UPT9,Q9H9T3,Q92794,Q9UBL3,Q8NEM7,Q8IUF8 17
Miscellaneous transport and binding events 0.3111960032516971 0.1745121116562133 0.8614630130900021 1.0 1.0 9 Q8TDW0,Q9HD23 2
Epigenetic regulation of gene expression 0.3956466178597601 0.1742008841123973 0.8617075907401615 1.0 1.0 45 P32780,P19447,Q9NY93,Q13185,Q92769,Q14839,Q9UHR5,Q9UIG0,P26358,Q9NR30,Q8WXI9,O00159,Q96KQ7,P62805,Q09028,Q15910,Q9BQG0,Q13547,Q15022,O95983,Q12873,Q96ST3,P49841,O75533,P17480,Q86YP4,O60264 27
Eukaryotic translation initiation 0.3754655974459114 0.1738779092632111 0.8619614140111236 1.0 1.0 101 P62847,Q9UBQ5,P46779,P62753,P61254,P18077,O15372,P11940,P61247,P55884,P62244,P56537,P08708,P84098,P42766,Q04637,Q14152,P62851,Q07020,P46782,Q13144,P62917,P62913,P62263,P60228,P46777,Q9Y3U8,P05387,P23588,Q14232,P40429,P62750,P62277,O75821,P18124,P62841,P62899,P39023,P62910,P62829,P83881,P35268,P20042,O75822,P63173,P62424,O60841,Q9NR50 48
Semaphorin interactions 0.3509551171452701 0.173751072889832 0.8620610975707781 1.0 1.0 25 P35579,O94887,P49841,Q13464,Q14195,Q13177,Q9Y490,Q9NWH9,O75116 9
Mitotic prometaphase 0.3073900944691332 0.1727459737223075 0.8628511051749044 1.0 1.0 101 Q9H900,Q9Y266,Q9Y6D9,O43683,Q9H3R5,O95347,P06493,P46060,O15078,Q96FJ2,Q14683,P53350,Q14008,Q96EA4,Q96RT8,Q53HL2,Q13362,Q15154,P67870,Q9Y6G9,P50748,Q9BPX3,P23258,P19784,Q7Z460,P04350,Q9NTJ3,O43264,Q14738,P49454,Q14980,Q96BD8,P14635,Q8WYP5,Q8N3U4,Q9NTI5 36
Antigen processing ubiquitination proteasome degradation 0.3708394703950597 0.1727223649608362 0.8628696633053619 1.0 1.0 100 Q9UJX6,Q13200,Q9UJX4,P25787,P25788,Q99460,O00232,Q92990,P19474,Q92530,Q8TDB6,Q16763,O75832,Q05086,Q13049,Q9BSL1,P46934,O43164,Q9UNE7,P51665,Q15345,Q14669,Q9UII4,Q63HN8,Q8NEZ5,P28070,P61088,Q7Z6Z7,P49721,Q9UIQ6,O94822,Q9ULT8,P29144,P48556,Q8TBC4,P62333,P20618,P63208,Q7Z6E9,P49427,Q15386,Q13309,Q13867,Q9H1A4,Q6UWE0,Q13618,Q96J02,O94874,Q93034,Q99436,P61086,Q5T4S7,Q15008,Q06323,P68036 55
Signaling by vegf 0.3682999568160009 0.1722286650585867 0.863257763128682 1.0 1.0 33 P14923,Q14185,Q13685,Q13464,P46108,O00459,Q96F07,Q13177,P35221,Q9Y6W5,P04792,P06241,O75116,P19174,Q9UQB8,P60953,Q8WUW1 17
Intracellular signaling by second messengers 0.3303018514869255 0.1718590755253222 0.8635483208100352 1.0 1.0 100 Q13200,P25787,P25788,P27361,Q9HC52,Q9UHA4,Q99460,O00232,O00459,Q92530,Q14839,O75832,O00308,O43815,P46934,Q9UNE7,P51665,P62993,Q8WXI9,Q13362,P28070,Q93009,Q9NWH9,Q15382,P28482,O15111,P49721,P67870,P48556,P20618,Q15910,P19784,P19174,Q13547,Q16537,Q05655,Q15022,O95983,P10644,Q14738,Q12873,P49841,O60341,P84095,Q86YP4,O43865,P06241,Q14781,Q15008,Q99436,Q06323 51
S phase 0.2729108115295829 0.170519354329511 0.8646017147029956 1.0 1.0 99 P18858,Q13200,Q9UJX4,P49643,P25787,P35251,Q9UJX6,P25788,Q99460,O00232,Q92530,P27694,Q16763,Q9Y248,Q9UQE7,O75832,P11802,O60216,Q14683,P51665,O43913,P49642,Q5TKA1,P33991,P28070,P25205,P15927,P40938,P49721,Q9BRX5,P41440,P62333,P48556,P20618,Q09028,P28340,P51530,P49841,Q13309,Q07864,P35244,Q9H1A4,P12004,Q15008,Q99436,Q8N3U4,Q06323,Q9NTI5 48
Telomere maintenance 0.3845011600702239 0.1690348733179341 0.8657692111274715 1.0 1.0 42 P18858,P35251,Q5H9R7,Q9UER7,P41440,Q8WVB6,P35244,P49642,Q9NPE3,P28340,P12004,P24928,O60832,Q9BUR4,P15927,P51530 16
Hedgehog on state 0.3864235090124745 0.1689694848490674 0.8658206438042166 1.0 1.0 43 P25787,P49721,P32121,P51665,Q92530,P20618,Q13618,P28070,O75832,Q96J02,Q99436,P48729,Q9Y496 13
Trna modification in the nucleus and cytosol 0.3329489192935834 0.1689599919448778 0.8658281106950947 1.0 1.0 19 Q9H974,Q7Z4G4,Q96PZ0,Q9UBP6 4
Mitotic g2 g2 m phases 0.2728778692040071 0.168382238068748 0.8662825805654009 1.0 1.0 97 P49721,Q15154,P49454,P25787,P53350,Q14008,Q96RT8,Q5TKA1,Q7Z460,P28070,P14635,Q99436,O15078,O14974 14
Mapk family signaling cascades 0.2680861253514512 0.1683750805097714 0.8662882110862931 1.0 1.0 97 Q13200,P25787,Q9UHA4,O00459,Q92530,Q13177,Q9Y490,Q96S59,O75832,P04792,P06493,P46940,P51665,Q13362,P28070,Q9NWH9,P32121,P36507,P28482,P49721,O15020,P48556,P20618,P29353,Q14168,P18206,Q16537,Q14738,Q02750,Q13813,P41240,Q13618,Q01082,P06241,Q15008,Q99436,P60953 37
Tp53 regulates transcription of genes involved in g2 cell cycle arrest 0.3095010939285976 0.1676193368032804 0.8668827578652742 1.0 1.0 10 O14965,P06493,P14635 3
Host interactions of hiv factors 0.2466892314712468 0.1672864523213358 0.8671446634134579 1.0 1.0 96 P25787,Q92530,O75832,P46060,O75475,O95782,P56377,O15504,P35658,P51665,Q9BVL2,P17096,P28070,Q9BXS5,P49721,P20618,P12270,Q93034,Q99436 19
Signaling by wnt 0.3150891218160915 0.1664581969085575 0.8677963781917215 1.0 1.0 95 P25787,Q92530,O43318,O75832,P48729,O95782,P09471,P51665,Q96QK1,Q00610,Q13362,P28070,Q9UBL3,P32121,O14641,P49721,P67870,P20618,P19784,O60493,Q16537,Q14738,P49841,P60763,P51532,P63218,P56545,Q04727,Q13618,Q99436 30
Formation of rna pol ii elongation complex 0.3604426916030929 0.1656696858321274 0.8684169035427554 1.0 1.0 32 Q14241,Q7KZ85,P19447,P52298,Q6PD62,P55199,P13984,P23193,P24928,Q9Y5B9,P50750,O00267 12
Dna replication 0.2519793414644682 0.165150778010951 0.8688253066207179 1.0 1.0 94 P18858,Q13200,Q9UJX4,P49643,P25787,P35251,Q9UJX6,P25788,O00232,Q92530,P27694,Q16763,Q9Y248,O75832,P51665,O43913,P49642,Q7L590,P33991,P28070,P15927,P40938,P49721,O00311,Q9BRX5,P41440,P48556,P20618,P28340,P51530,O60684,Q13309,Q07864,P52294,P35244,Q9H1A4,P12004,Q15008,Q99436,Q06323 40
Apoptosis 0.2432468887317024 0.1651446811650045 0.8688301053125249 1.0 1.0 94 P15924,P49721,P25787,P26583,Q15149,Q13464,P51665,Q07157,P20618,P09429,P28070,O75832,Q99436,P42771,Q96FJ2,O76075,Q14790 17
Inactivation of csf3 g csf signaling 0.3557714924015591 0.1641856724966457 0.8695849797395854 1.0 1.0 5 Q93034,P42224 2
Rhob gtpase cycle 0.3492108311949046 0.1628559131363974 0.8706318835379363 1.0 1.0 28 P14923,Q9UDY2,Q9H2G2,Q07960,Q9NQW6,Q13464,Q16513,P41440,Q9NSV4,Q9H8V3,Q13017,O75116,O00161,O60610 14
Metalloprotease dubs 0.354955160012761 0.1628058927009595 0.8706712684707185 1.0 1.0 5 P38398,Q15018 2
G2 m checkpoints 0.3355360052284545 0.1626524390247093 0.8707920963434943 1.0 1.0 91 P49721,Q92547,P25787,O00311,Q9UQ84,Q13472,Q9BX63,P28070,P61088,P14635,Q99436,O60921,Q13535 13
Cellular response to starvation 0.3326169870228532 0.1625834801762305 0.870846394825703 1.0 1.0 91 P62847,P46779,Q9UHA4,P62753,P61254,P18077,Q9Y5K8,P61247,P62244,P08708,P84098,P42766,P62851,Q07020,P46782,P62917,P62913,P62263,Q15382,P38606,P46777,O75348,Q9Y3U8,Q96EE3,P05387,P40429,P62750,P18124,P62841,Q92616,P62899,P39023,P62910,P62829,P83881,P21283,P20042,P35268,P63173,P62424 40
Metabolism of vitamins and cofactors 0.3954114101345981 0.1616839965583855 0.8715547076091632 1.0 1.0 53 O75874,Q969G6,P49914,P35270,P41440,Q9NRN7,P35030,P05165,P34897,P50747,Q8NFF5,Q96CD2,P34896,P43490,O00763 15
Selenoamino acid metabolism 0.3170611030818104 0.1612652706391286 0.8718844752167099 1.0 1.0 90 P62847,P46779,P62753,P61254,P18077,O43252,P61247,P49591,P62244,Q13155,P08708,P84098,P42766,P62851,Q15046,Q07020,P46782,P62917,P62913,P62263,P46777,Q9Y3U8,P05387,O43324,P40429,P62750,Q16881,P18124,P62841,P62899,P39023,P62910,P62829,P83881,P35268,P63173,P62424 37
Sars cov infections 0.4066056029629118 0.1597877285237004 0.873048291092648 1.0 1.0 66 Q99720,Q12873,Q9UHD2,P78362,Q14839,O75116 6
Nonsense mediated decay nmd 0.360069260894067 0.1597673778056145 0.8730643226708072 1.0 1.0 87 P62847,P46779,P62753,P61254,P18077,Q9Y5S9,P11940,P61247,P62244,P08708,P84098,P42766,Q04637,P52298,P62851,Q07020,P46782,P62917,P62913,P62263,Q15287,P46777,P38919,Q9Y3U8,P05387,Q9BZI7,P40429,P62750,P62277,P18124,P62841,P62899,P39023,P62910,P62829,P83881,P35268,P63173,P62424 39
Regulation of runx3 expression and activity 0.3651171323470571 0.1596770065950326 0.8731355145536817 1.0 1.0 37 P25787,P49721,P51665,P20618,P28070,O75832,Q99436,P42771 8
Synthesis of dna 0.2354598102167126 0.1576573625277703 0.8747267999826545 1.0 1.0 87 P18858,Q13200,Q9UJX4,P49643,P25787,P35251,Q9UJX6,P25788,Q99460,O00232,Q92530,P27694,Q16763,Q9Y248,O75832,P49736,P49005,P51665,O43913,P35998,P49642,P33991,P28070,P25205,P15927,P40938,P49721,Q9BRX5,P41440,P62333,P48556,P20618,P63208,P28340,P51530,Q13309,Q07864,P35244,Q9H1A4,P12004,Q15008,Q99436,Q06323 43
Rho gtpases activate formins 0.4015220630777736 0.157158538234558 0.8751199038701682 1.0 1.0 69 Q9Y266,Q9H900,Q9Y6D9,O43683,Q9H3R5,Q9NSV4,Q8WUM0,P46060,O60610,Q96FJ2,Q9BZD4,P53350,Q14008,O60879,Q96EA4,Q53HL2,Q13362,O14641,Q96EE3,Q9Y6G9,P50748,Q7Z460,P04350,Q16537,Q8WYP5,O43264,Q14738,Q9H081,P49454,O00139,Q96BD8,O14777,P60953 33
Metabolism of nucleotides 0.3839602165579965 0.1566098591845614 0.8755523319276237 1.0 1.0 50 P04818,Q9H773,O76075 3
Sumoylation 0.2779253454872689 0.1556393005834354 0.8763173450216344 1.0 1.0 85 Q9P0U3,Q9HC52,O14965,Q9UQE7,P42771,P46060,O60216,Q14683,P26358,O15504,P35658,Q9UER7,Q9BVL2,Q53HL2,Q8TEM1,P49790,Q96EE3,Q9UBT2,P45973,Q96MG7,P11388,Q12873,Q96ST3,O75928,Q02880,P38398,P09874,P12270,Q13263,Q14781,Q8N3U4,O75925 32
Hiv life cycle 0.2489213583531632 0.1555395772180894 0.8763959554695897 1.0 1.0 85 P18858,Q99816,P19447,Q9Y5B9,P46060,P50750,P29083,O75475,Q14241,O15504,P35658,P52298,Q9BVL2,P17096,Q9H9H4,O00267,Q9H3P2,P55199,Q9HBM6,P24928,Q00403,P12270,P13984,P23193 24
Ripk1 mediated regulated necrosis 0.3046479709200623 0.1533032546822275 0.8781591341505377 1.0 1.0 12 P41440 1
Atf4 activates genes in response to endoplasmic reticulum stress 0.3015532071851149 0.1523590210081632 0.878903776179097 1.0 1.0 11 Q9Y2L1,Q13868,Q06265 3
Rhoq gtpase cycle 0.3311446433155697 0.1522140602523957 0.8790181047046641 1.0 1.0 24 P14923,Q07960,P46940,Q9NSV4,Q13017,O00308,Q9HD26 7
Regulation of pten stability and activity 0.3687748531237452 0.1521023250010497 0.8791062304602246 1.0 1.0 44 P25787,P49721,P46934,P67870,P51665,P20618,P19784,P28070,O75832,Q99436,O00308 11
Cross presentation of soluble exogenous antigens endosomes 0.3586328482792328 0.152015799599865 0.8791744741992511 1.0 1.0 38 P25787,P49721,P51665,P20618,P28070,O75832,Q99436,Q9UBG0 8
Mitotic g1 phase and g1 s transition 0.3017587073933857 0.1517253648308074 0.8794035505393765 1.0 1.0 81 Q13200,P49643,P25787,P25788,Q99460,O00232,Q92530,P27694,P11802,O75832,P42771,P04818,P06493,P51665,O43913,P49642,Q5TKA1,Q7L590,P33991,P28070,P25205,P15927,Q00534,P49721,O00311,P62333,P48556,P20618,Q09028,Q13547,P11388,P63151,Q13309,Q07864,P35244,P12004,P14635,Q15008,Q99436,Q06323 40
Rhou gtpase cycle 0.3188477740015639 0.1507020821684623 0.8802107306628542 1.0 1.0 19 O43396,P60953,P46940,Q13813,Q93008,Q03001,O00459,Q13177,Q00610,Q01082,O00308 11
Mitotic spindle checkpoint 0.3841181516351626 0.150472591237938 0.8803917735380102 1.0 1.0 64 Q9UJX6,Q9Y266,Q9H900,Q9Y6D9,O43683,Q9H3R5,Q16763,P46060,Q96FJ2,Q9BZD4,P53350,Q14008,Q96EA4,Q53HL2,Q13362,Q96EE3,Q9Y6G9,P50748,Q7Z460,Q16537,Q8WYP5,O43264,Q14738,Q9H081,P49454,O00139,Q96BD8,Q9H1A4,O14777 29
Ub specific processing proteases 0.2070038757672408 0.1501669718742019 0.8806328830033714 1.0 1.0 80 P49721,P25787,O94966,P54578,Q96FW1,Q9HBM6,Q9UPT9,P28070,Q9NZL9,Q99436,P32121 11
Transcription of the hiv genome 0.3453957949257434 0.1500844580870449 0.880697981742341 1.0 1.0 32 Q14241,Q00403,P19447,P52298,P55199,Q9HBM6,P13984,P23193,Q9Y5B9,P29083,O00267 11
Factors involved in megakaryocyte development and platelet production 0.3737361441875517 0.1491328913600136 0.8814487725379736 1.0 1.0 51 Q9BUF5,Q96Q89,Q96N67,Q9Y496,Q9NRW7,Q14185,Q9H0B6,P45973,P52907,O95239,P52732,Q07866,P04350,Q9NSK0,Q96ST3,O60341,Q13572,O00139,P27144,P60953,Q9BW19 21
Dna double strand break repair 0.3804748174461287 0.149081942791333 0.8814889742186645 1.0 1.0 63 P35251,Q9UGN5,Q9UQ84,Q9BX63,Q5UIP0,P49916,Q6ZW49,Q92547,P60510,Q13472,P61088,Q92889,P15927,P40938,Q92878,P41440,Q14676,P28340,O00213,Q13535,P51530,O14757,Q9NXR7,Q07864,Q04323,P35244,P38398,P09874,P12004,O60264,O60921 31
Interleukin 1 signaling 0.3722965976281152 0.148938111560225 0.8816024679106842 1.0 1.0 50 O15111,P25787,P49721,Q02750,P51665,Q92530,P20618,P09429,O43318,P28070,O75832,P61088,Q99436,Q9H0E2 14
Response of eif2ak4 gcn2 to amino acid deficiency 0.3378465175391211 0.1483248336952896 0.8820864176683934 1.0 1.0 76 P62847,P46779,P62753,P61254,P18077,P61247,P62244,P08708,P84098,P42766,P62851,Q07020,P46782,P62917,P62913,P62263,P46777,Q9Y3U8,P05387,P40429,P62750,P18124,P62841,Q92616,P62899,P39023,P62910,P62829,P83881,P35268,P20042,P63173,P62424 33
Eukaryotic translation elongation 0.3195721895539932 0.1482327372278461 0.8821590966284398 1.0 1.0 77 P62847,P46779,P62753,P61254,P18077,P61247,P62244,P08708,P84098,P42766,P62851,Q07020,P46782,P62917,P62913,P62263,Q9Y3U8,P46777,P05387,P40429,P62750,P18124,P62841,P62899,P39023,P62910,P62829,P83881,P35268,P63173,P62424 31
Meiosis 0.3335959962348954 0.1481726135134139 0.8822065444672493 1.0 1.0 27 Q14683,Q9BTC0,Q92878,Q8WXH0,Q13472,P35244,P38398,Q13535,P27694,P11802,Q9UQE7,O94901,P15927,Q8N3U4,Q8NF91,O60216 16
Reproduction 0.3335959962348954 0.1481726135134139 0.8822065444672493 1.0 1.0 27 Q14683,Q9BTC0,Q92878,Q8WXH0,Q13472,P35244,P38398,Q13535,P27694,P11802,Q9UQE7,O94901,P15927,Q8N3U4,Q8NF91,O60216 16
Sumoylation of chromatin organization proteins 0.3570900742316255 0.1480062615117988 0.8823378266981932 1.0 1.0 40 O15504,P35658,Q12873,Q9HC52,P45973,O75928,Q9BVL2,Q14781,O75925 9
Apc c cdc20 mediated degradation of cyclin b 0.3006026997746136 0.1479418638687708 0.8823886491142932 1.0 1.0 12 Q9UJX6,Q16763,Q9H1A4,P14635 4
Degradation of beta catenin by the destruction complex 0.3724937407975023 0.1478424454715003 0.8824671107495112 1.0 1.0 52 P25787,P49721,Q14738,P49841,P51665,P20618,Q04727,P56545,Q13362,P28070,O75832,Q99436,P48729 13
Tp53 regulates transcription of dna repair genes 0.3478193215057297 0.1473066683067274 0.8828899693511163 1.0 1.0 35 Q14241,P19447,Q9H3P2,P55199,Q9NYV4,P38398,Q9NVI1,Q8WX92,Q13535,P13984,Q9BXW9,P24928,P23193,Q9Y5B9,P50750,Q08945,O14757,O00267 18
E2f mediated regulation of dna replication 0.2975113696135902 0.1469677451952812 0.8831574794278421 1.0 1.0 11 P49642 1
Stat5 activation 0.5937244201910002 0.1461195946758163 0.8838269781214514 1.0 1.0 2 P62993 1
Pi 3k cascade fgfr2 0.5937244201910002 0.1461195946758163 0.8838269781214514 1.0 1.0 2 P62993 1
Pi 3k cascade fgfr3 0.5937244201910002 0.1461195946758163 0.8838269781214514 1.0 1.0 2 P62993 1
Stat5 activation downstream of flt3 itd mutants 0.5937244201910002 0.1461195946758163 0.8838269781214514 1.0 1.0 2 P62993 1
Pi 3k cascade fgfr1 0.5937244201910002 0.1461195946758163 0.8838269781214514 1.0 1.0 2 P62993 1
Pd 1 signaling 0.5937244201910004 0.1461195946758163 0.8838269781214514 1.0 1.0 2 P41240 1
Pi 3k cascade fgfr4 0.5937244201910002 0.1461195946758163 0.8838269781214514 1.0 1.0 2 P62993 1
Pten regulation 0.3492881286008167 0.1461034277506182 0.8838397405024772 1.0 1.0 72 P25787,P25788,P27361,Q13200,Q9HC52,Q9UHA4,Q99460,O00232,Q92530,Q14839,O75832,O00308,P46934,Q9UNE7,P51665,Q8WXI9,Q93009,P28070,Q15382,P28482,P49721,P67870,P48556,P20618,Q15910,P19784,Q13547,Q15022,O95983,Q12873,O60341,Q86YP4,Q15008,Q14781,Q99436,Q06323 36
Formation of incision complex in gg ner 0.3124547311146184 0.1458171827824056 0.8840657109923753 1.0 1.0 18 Q86WJ1,Q9UGN5,P19447,Q13620,P61956,P35244,P09874,P27694,Q92889,P61088,P15927,O75925 12
Pi3k akt signaling in cancer 0.3055185480672921 0.1454909769250859 0.8843232393224538 1.0 1.0 15 O15111,P49841,P84095,O00459,P06241,Q9NWH9,O43815 7
Neddylation 0.2569868612692063 0.1449587588710273 0.8847434334387194 1.0 1.0 75 P25787,Q92530,O75832,Q15345,P51665,Q8NEZ5,P61962,P28070,Q9H9Q2,P49721,Q86VP6,P20618,Q8TBC4,Q13564,Q13309,Q13618,Q99627,Q15008,Q93034,Q96GG9,Q99436 21
Auf1 hnrnp d0 binds and destabilizes mrna 0.3556312093228483 0.1447545517752911 0.8849046666081233 1.0 1.0 42 P25787,P49721,Q04637,P51665,Q92530,P20618,P04792,P11940,O75832,P28070,Q99436 11
Dual incision in tc ner 0.3472547108303216 0.144121787786848 0.8854043001658247 1.0 1.0 37 P35251,Q9HCS7,P19447,P41440,Q13620,Q07864,P35244,P27694,P12004,P23193,O60306,Q92889,P24928,P28340,P15927,P40938 16
Activation of the mrna upon binding of the cap binding complex and eifs and subsequent binding to 43s 0.363719464911287 0.1436492608575758 0.8857774394831002 1.0 1.0 51 P62847,Q9UBQ5,P62753,O15372,P11940,P61247,P55884,P62244,P56537,P08708,Q04637,P62851,P46782,P62263,P60228,P23588,O75821,P62277,P62841,P20042,O75822 21
Rho gtpases activate wasps and waves 0.3144297805426555 0.1432360869936478 0.8861037303529775 1.0 1.0 20 P28482,Q96F07,O15144,P62993,Q9NZQ3,Q9Y6W5,Q9UQB8,P61160,P60953,Q8WUW1 10
Tcf dependent signaling in response to wnt 0.3574790707724301 0.1430240317596349 0.8862712017072056 1.0 1.0 65 P25787,Q92530,O75832,P48729,P51665,Q13362,Q9UBL3,P28070,O14641,P49721,P67870,P20618,P19784,Q16537,Q14738,P49841,P51532,Q04727,Q13618,Q99436 20
Metabolism of water soluble vitamins and cofactors 0.3513571525546584 0.1427794175957307 0.8864643928974185 1.0 1.0 41 Q969G6,P49914,P41440,Q9NRN7,P35030,P05165,P34897,P50747,Q8NFF5,Q96CD2,P34896,P43490,O00763 13
Transcriptional regulation by runx1 0.3080923283046334 0.1419534066534092 0.8871168089935653 1.0 1.0 71 O14497,P25787,Q13200,Q9HC52,Q92530,Q96GM5,O75832,Q07157,O15047,P51665,Q9UBL3,P28070,Q00534,P49721,Q86U86,P67870,Q92925,P48556,P20618,Q68CP9,P19784,Q96ST3,P51532,Q15008,Q14781,Q96J02,Q99436 27
Asymmetric localization of pcp proteins 0.3442729610338539 0.1398357285951065 0.888789783289031 1.0 1.0 39 O14641,P25787,P49721,P51665,P20618,P28070,O75832,Q99436 8
Rab regulation of trafficking 0.3454982349141494 0.139768832122818 0.8888426398867448 1.0 1.0 40 Q9UJY4,Q9Y2L5,Q4KMP7 3
Beta catenin independent wnt signaling 0.3511544757928505 0.1393530633061241 0.8891711604350592 1.0 1.0 60 O14641,O95782,P25787,P49721,P09471,P60763,P51665,P20618,P63218,O43318,P28070,Q99436,P32121 13
Interferon signaling 0.2676265794784819 0.1387968039712838 0.889610719601929 1.0 1.0 69 P19474,O60573,O15504,P35658,P19525,P46934,Q04637,Q9BVL2,P61088,Q8TEM1,P49790,P38919,O43432,Q9Y3Z3,P19174,O15344,P29372,O75369,P78344,P52294,Q14258,P12270,O75925 23
Transport of mature transcript to cytoplasm 0.312701496714492 0.1385062941864406 0.8898402955208886 1.0 1.0 67 Q6UN15,Q9P2I0,O75152,Q9Y5S9,Q96QD9,Q05519,Q13243,O15504,P35658,P52298,Q9BVL2,Q10570,Q15287,Q9Y3Y2,Q8TEM1,P49790,P38919,Q16629,Q8IYB3,Q9BZI7,Q08170,P84103,Q9C0J8,P12270,Q92620 25
Fc epsilon receptor fceri signaling 0.3441385539956466 0.1381761502593577 0.8901012036104607 1.0 1.0 61 P25787,P25788,P27361,Q13200,Q99460,O00232,O00459,Q92530,Q13177,O14733,O43318,O75832,Q15750,P51665,P62993,P28070,P61088,P28482,O15111,P49721,P62333,P48556,P20618,P29353,P63208,P19174,O43865,Q15008,P06241,Q99436,Q06323 31
Mrna splicing minor pathway 0.3335410061334558 0.1373300438664293 0.8907699238341396 1.0 1.0 34 O75533,P52298,Q86XP3,Q16629,P67809,P13984,P24928 7
Clec7a dectin 1 signaling 0.3489806327314179 0.1369924992487808 0.8910367239471195 1.0 1.0 52 O15111,P25787,P49721,P51665,Q92530,P20618,Q8TBC4,O43318,P28070,O75832,P61088,Q99436,Q14790 13
Extracellular matrix organization 0.3295693716853332 0.1366633957515097 0.891296863956055 1.0 1.0 32 P17655,P20810,Q32P28,P12814,P07942,Q15149,P13674,O15460 8
Fcgr3a mediated il10 synthesis 0.2801421721957047 0.1366162676167003 0.8913341173700007 1.0 1.0 7 P10644,P06241,P19174 3
Cellular response to heat stress 0.1487228161696381 0.1362881644245332 0.8915934800026497 1.0 1.0 67 O15504,P35658,Q9BVL2,Q53FT3,Q99543,O75190,Q13535 7
Tnfr2 non canonical nf kb pathway 0.3420823024467901 0.1357887141164791 0.8919883132505049 1.0 1.0 43 O15111,P25787,P49721,P51665,P20618,Q8TBC4,P28070,Q99436 8
Glutathione conjugation 0.2967969161382541 0.1355686513067058 0.8921622892398595 1.0 1.0 15 O75223 1
Glucagon like peptide 1 glp1 regulates insulin secretion 0.3000947486995043 0.135487150991225 0.8922267226076461 1.0 1.0 6 P46940 1
Trna processing 0.2162316723984466 0.1352679020491473 0.8924000622489008 1.0 1.0 66 O15504,P35658,Q9UBP6,Q9BVL2,Q92499,Q52LJ0,P12270,P78346,Q96PZ0,Q9H974,Q969Y2,Q7Z4G4 12
Rac1 gtpase cycle 0.3442497224282052 0.1352015561047415 0.8924525167981399 1.0 1.0 51 Q07960,Q96F07,Q13177,Q9NSV4,Q86Y07,Q8WUW1,Q8N5V2,O94887,P46940,Q16513,Q96N67,Q14185,Q9Y2I1,Q9H8V3,Q13017,Q9UQB8,O00161,O15498,Q9Y4F1,Q96AC1,P60953 21
Cyclin a cdk2 associated events at s phase entry 0.3415631014253389 0.1350982772673817 0.8925341722335016 1.0 1.0 44 P25787,P49721,Q13309,P51665,P20618,Q5TKA1,P28070,O75832,Q99436 9
Degradation of dvl 0.3349071913648142 0.1339648120808106 0.893430399460871 1.0 1.0 39 O14641,P25787,P25788,Q13200,P49721,P51665,O00232,Q92530,P48556,P20618,Q13618,P28070,O75832,Q15008,Q99436,Q06323 16
Regulation of mrna stability by proteins that bind au rich elements 0.2688176436969569 0.1337072109536463 0.893634102852968 1.0 1.0 64 Q99436,P25787,P49721,P35658,Q13868,Q04637,P51665,Q92530,Q8IZH2,P20618,P04792,P11940,O75832,P28070,P39687,Q9Y2L1 16
Fceri mediated nf kb activation 0.3394887361839099 0.1334422611884919 0.8938436246510315 1.0 1.0 47 O15111,P25787,P49721,P51665,Q92530,P20618,O43318,P28070,O75832,P61088,Q99436 11
Pcp ce pathway 0.3378564996154509 0.1334340226403726 0.8938501397989054 1.0 1.0 53 O14641,O95782,P25787,P49721,P60763,P20618,P28070,Q99436,P32121 9
Regulation of runx2 expression and activity 0.3371783223974656 0.1332703689067802 0.8939795607213827 1.0 1.0 43 P25787,P25788,Q13200,Q99460,O00232,Q92530,P42224,O75832,Q9UNE7,P51665,P28070,P49721,P62333,P48556,P20618,P49841,Q13309,Q15008,Q99436,Q06323 20
Dna replication pre initiation 0.2350635941003082 0.133236404467805 0.8940064208902911 1.0 1.0 64 P25787,P25788,Q13200,P49643,Q99460,O00232,Q92530,P27694,O75832,P51665,O43913,P49642,Q7L590,P33991,P28070,P25205,P15927,P49721,O00311,P48556,P20618,O60684,Q07864,P52294,P35244,Q15008,Q99436,Q06323 28
Tbc rabgaps 0.2943242235492792 0.1329587665067144 0.8942259904597183 1.0 1.0 15 Q9UJY4,Q9Y3P9,Q9UJ41,Q4KMP7 4
Nucleotide excision repair 0.271435288792536 0.132769176893254 0.894375931782392 1.0 1.0 63 P18858,P35251,Q9UGN5,P19447,Q9H981,O60306,P49916,P61088,Q9H9Q2,P41440,P55199,P24928,P28340,Q86WJ1,Q07864,P09874,P23193,Q99627,Q9HCS7,O75925 20
Signaling by hedgehog 0.2683658082833453 0.1326869905302134 0.8944409319379782 1.0 1.0 63 P25787,P49721,P32121,P49841,P51665,P20618,P28070,O75832,P04350,Q99436,P48729,Q9Y496,O75386 13
Post chaperonin tubulin folding pathway 0.2835188106315336 0.132667824343676 0.8944560903345671 1.0 1.0 10 P04350,O75347,Q9BUF5,Q15813 4
Tcr signaling 0.3351266440267038 0.1321240956012991 0.8948861374516532 1.0 1.0 51 O15111,P25787,P49721,P51665,P20618,Q8N8S7,O43318,P28070,P61088,P19174,Q99436 11
Budding and maturation of hiv virion 0.284463894967186 0.1313304202850306 0.8955139282845552 1.0 1.0 11 O75351,Q99816,Q9UQN3,Q8WUM4,Q9NZZ3,Q96FZ7,Q9H444,Q8WUX9,Q9UN37,Q9H9H4 10
Mhc class ii antigen presentation 0.3075769047497808 0.131249976733239 0.8955775621502085 1.0 1.0 59 O95487,P56377,O94855,O15020,O94979,O95486,P52907,Q9H0B6,Q9BXS5,Q9Y496,Q9NSK0,Q96FJ2 12
Signaling by mras complex mutants 0.3633633633633681 0.1312335818269753 0.8955905312182126 1.0 1.0 4 P10398,P31946,Q9UQ13 3
Mitotic prophase 0.2299838477006601 0.1310996509384354 0.8956964772908267 1.0 1.0 62 O15504,P35658,Q14980,P53350,Q9BVL2,Q99986,P12270,Q86Y07,P14635,Q9NTJ3 10
Dectin 1 mediated noncanonical nf kb signaling 0.3318825689934556 0.1307709434267307 0.8959565093557613 1.0 1.0 43 O15111,P25787,P49721,P51665,P20618,Q8TBC4,P28070,Q99436 8
C type lectin receptors clrs 0.309030217316961 0.130623253288411 0.8960733468696866 1.0 1.0 58 P25787,P25788,Q13200,Q99460,O00232,Q92530,Q13177,O43318,O75832,Q15750,P51665,P28070,P61088,Q14790,O15111,P49721,P62333,P48556,P20618,Q8TBC4,P63208,Q05655,O43865,Q15008,P06241,Q99436,Q06323 27
The role of gtse1 in g2 m progression after g2 checkpoint 0.3308444162160919 0.1305854014344088 0.896103291794764 1.0 1.0 50 Q99436,P25787,P49721,P53350,P51665,P20618,P28070,O75832,P04350,P14635 10
Synthesis of pyrophosphates in the cytosol 0.5844474761255162 0.1305850623297779 0.8961035600640035 1.0 1.0 2 Q13572 1
Chromosome maintenance 0.3313147526089602 0.1305218153608511 0.8961535956139315 1.0 1.0 49 P18858,P35251,Q5H9R7,Q9H3R5,Q9BUR4,Q9UER7,Q96T23,P49642,Q9NPE3,P15927,P40938,P41440,P24928,O60832,P28340,P51530,Q8WVB6,P35244,Q71F23,P12004,O60264 21
Hedgehog off state 0.3235231135914775 0.1302880683728051 0.8963385196645166 1.0 1.0 54 P25787,P25788,Q13200,Q99460,O00232,Q92530,O75832,P48729,Q8NCM8,O75386,Q9BUF5,P51665,P28070,Q9Y496,P49721,P62333,P48556,P20618,P04350,P10644,P49841,Q15008,Q96J02,Q99436,Q06323 25
Degradation of axin 0.3264069231246266 0.1302800711333255 0.8963448466132988 1.0 1.0 37 P25787,P49721,P51665,P20618,P28070,O75832,Q99436 7
Apc c mediated degradation of cell cycle proteins 0.3000175775032419 0.1296876299369125 0.8968135697905586 1.0 1.0 58 Q9UJX6,P25787,P49721,Q13309,P53350,P51665,Q92530,P20618,O14965,Q9H1A4,Q16763,P28070,O75832,P14635,Q99436 15
Diseases of programmed cell death 0.3153433814591838 0.1295591391541992 0.896915232921293 1.0 1.0 29 P20810,P17655,P49642,Q15910,P42771,Q14790 6
Aggrephagy 0.2927450791917954 0.1293742388008665 0.8970615308110013 1.0 1.0 16 Q9Y6G9,Q96FJ2,P61088 3
Switching of origins to a post replicative state 0.2123725593210425 0.1289002244472711 0.8974365990683251 1.0 1.0 60 Q9UJX6,P25787,P25788,Q9UJX4,Q13200,Q99460,O00232,Q92530,Q16763,O75832,P51665,O43913,P33991,P28070,P25205,P49721,P62333,P48556,P20618,Q13309,Q9H1A4,Q15008,Q99436,Q06323 24
Regulation of hsf1 mediated heat shock response 0.1635603488493172 0.1288318289208309 0.8974907195574104 1.0 1.0 60 O15504,P35658,Q9BVL2,Q53FT3,Q99543,O75190,Q13535 7
Defective intrinsic pathway for apoptosis 0.2940310298579399 0.1287660152951543 0.8975427974722812 1.0 1.0 17 P17655,P42771,P20810 3
Rrna modification in the nucleus and cytosol 0.2668139466157829 0.1286511800373946 0.8976336669581062 1.0 1.0 59 P62753,Q8TED0,Q96EU6,Q9UNQ2,Q9NV31,Q68CQ4,O15213,Q14690,P46087,Q13601,P62263,Q14692,Q9NPE3,Q9BVI4,Q9BVJ6,Q9H6R4,Q8IY37,Q8IWA0,Q9Y6V7,O43818,Q9Y2R4,Q9Y2X3,O60832,Q9H0A0,Q9NRX1,O43709,P78316,Q9H0S4 28
Rna polymerase ii transcription termination 0.3257742580319521 0.1285760359464905 0.8976931294306172 1.0 1.0 48 Q6UN15,Q9P2I0,O75152,P51003,Q9Y5S9,Q96QD9,Q05519,Q13243,P52298,Q10570,Q15287,Q9Y3Y2,Q16629,Q8IYB3,Q9BZI7,Q08170,P84103,Q9C0J8,Q92620 19
Negative regulation of notch4 signaling 0.3226481307616342 0.1272383864156485 0.8987517243054624 1.0 1.0 40 P25787,Q9Y6A5,P49721,P51665,P20618,P28070,O75832,Q99436 8
Transcriptional regulation by runx2 0.3081636282729607 0.1262750938205015 0.8995141706792118 1.0 1.0 52 P25787,P25788,P27361,Q13200,Q99460,O00232,Q92530,P42224,P11802,O75832,P06493,Q9UNE7,P51665,P28070,P28482,P49721,P62333,P48556,P20618,P49841,Q13309,Q96PK6,Q15008,P14635,Q99436,Q06323 26
Regulation of ras by gaps 0.3200371766014719 0.1262726210903206 0.8995161279655262 1.0 1.0 39 P25787,P25788,Q13200,P49721,P51665,O00232,Q92530,P48556,P20618,Q13618,P28070,O75832,Q15008,Q99436,Q06323 15
Scf skp2 mediated degradation of p27 p21 0.3204853345233291 0.126156652948908 0.8996079230811864 1.0 1.0 41 P25787,P25788,Q13200,P49721,Q13309,Q99460,O00232,P51665,Q92530,P62333,P48556,P20618,P11802,P28070,O75832,Q15008,Q99436,Q06323 18
Antigen processing cross presentation 0.2748359614275493 0.1261036796493151 0.8996498547870164 1.0 1.0 56 O15111,P25787,Q9UIQ6,P49721,P51665,P20618,P09429,P28070,O75832,Q99436,O00161,Q9UBG0 12
Autophagy 0.2420420511785341 0.126029696999394 0.8997084171867205 1.0 1.0 57 Q99816,P67870,Q9Y6G9,P54646,P19784,P50542,P61088,Q15382,Q676U5,Q9H9H4,Q96FJ2,Q9NT62 12
Signaling by the b cell receptor bcr 0.3076784995682884 0.1255752529228616 0.9000681531653345 1.0 1.0 51 P25787,P25788,Q13200,Q99460,O00232,Q92530,O43318,O75832,Q13586,P51665,P62993,P62942,P28070,O15111,P49721,P62333,P48556,P20618,O43865,Q15008,P06241,Q99436,Q06323 23
Stabilization of p53 0.3177076742516428 0.1251033639073578 0.9004417202085595 1.0 1.0 40 P25787,P49721,P51665,P20618,P28070,Q99436,P42771 7
Hcmv infection 0.2182453331472338 0.12471665253675 0.900747873518246 1.0 1.0 56 Q99816,O15504,P35658,Q9Y6G9,Q9UER7,Q9BVL2,Q9HD42,P12270,Q15910,Q9H9H4,Q96FJ2 11
Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1 0.3030319369080625 0.1241598190100994 0.9011887357899804 1.0 1.0 50 Q9UJX6,P25787,P49721,Q13309,P53350,P51665,Q92530,P20618,O14965,Q9H1A4,P28070,O75832,Q99436 13
Metabolism of polyamines 0.3142225581631235 0.1237585523714659 0.9015064498644654 1.0 1.0 39 Q99436,P25787,P25788,Q13200,P49721,P51665,O00232,Q92530,P48556,P20618,P28070,O75832,Q15008,P19623,Q06323 15
Estrogen dependent gene expression 0.3075279001589205 0.1230149245046558 0.9020952796845976 1.0 1.0 31 P50750,Q15185,Q14683,O60341,Q8N3U4,P13984,P24928,Q15648,O14646,O60216 10
Apoptotic execution phase 0.3077016490151029 0.1225909572972869 0.9024310154607018 1.0 1.0 32 P15924,P26583,Q13464,P09429,Q15149,O76075,Q14790,Q07157 8
Sumoylation of dna damage response and repair proteins 0.288976645136082 0.1221379397748671 0.9027897752002862 1.0 1.0 50 O15504,P35658,Q9HC52,O75928,Q9BVL2,P09874,Q14781,P42771,Q96MG7,O75925 10
Antiviral mechanism by ifn stimulated genes 0.2405739576783839 0.1219195749599388 0.9029627127013452 1.0 1.0 53 O60573,O15504,P35658,P19525,P46934,Q04637,Q9BVL2,P61088,Q8TEM1,P49790,P38919,Q96EE3,O43432,P19174,O75369,P78344,P52294,P21333,P12270,Q14258 20
Cation coupled chloride cotransporters 0.578990450204643 0.1219102831079088 0.9029700716340752 1.0 1.0 2 P55011 1
Mapk6 mapk4 signaling 0.2917811589211894 0.1217674038526702 0.9030832297616108 1.0 1.0 49 P25787,P25788,Q13200,Q99460,O00232,Q16512,Q92530,Q13177,P04792,O75832,P06493,P25685,Q9HCE1,P51665,P35998,P28070,O14980,P49721,P62333,P48556,P20618,O00233,Q15008,Q99436,P62191,P60953,Q06323 27
Downstream signaling events of b cell receptor bcr 0.3016866270736825 0.1216394945798 0.9031845335682882 1.0 1.0 46 O15111,P25787,P49721,P51665,P20618,O43318,P28070,Q99436 8
G1 s dna damage checkpoints 0.3057607618075549 0.1210966429820989 0.9036144881215632 1.0 1.0 42 P25787,P49721,P51665,Q92530,P20618,P28070,O75832,Q99436,P42771 9
Rab gefs exchange gtp for gdp on rabs 0.3033774084153227 0.1203559702024911 0.904201168481018 1.0 1.0 32 Q9Y2L5 1
Uch proteinases 0.2784835723766798 0.1202007953763235 0.9043240877258596 1.0 1.0 49 P49721,P25787,P51665,P20618,Q9H981,P28070,Q99436 7
Transcription coupled nucleotide excision repair tc ner 0.2628448012188887 0.1198572379935816 0.9045962393386312 1.0 1.0 50 P18858,P35251,P19447,Q13620,O60306,P49916,Q92889,P15927,Q9H9Q2,P41440,P55199,P24928,P28340,Q07864,P35244,P12004,P23193,Q99627,Q9HCS7 19
Sealing of the nuclear envelope ne by escrt iii 0.2749658002736053 0.1198166493412861 0.9046283926913274 1.0 1.0 12 Q9BUF5,Q8NC56,Q9UQN3,Q9H444,Q96FZ7,P04350,Q9BVA1,Q8WUX9,Q9UN37,P68371,Q13885 11
Nuclear envelope ne reassembly 0.2207327662298067 0.1195249937053023 0.9048594398566556 1.0 1.0 51 Q9BVL2,Q86Y07,P14635 3
Resolution of abasic sites ap sites 0.2975727315402835 0.1190884331643362 0.9052052945258624 1.0 1.0 28 P18858,P29372,P35251,Q9UGN5,Q07864,Q96T60,P41440,P35244,P09874,P12004,P28340,P15927,P49916,P27695 14
Orc1 removal from chromatin 0.2439681274058888 0.119008711154682 0.9052684543288272 1.0 1.0 50 P25787,P25788,Q13200,Q99460,O00232,Q92530,O75832,P51665,O43913,P33991,P28070,P25205,P49721,P62333,P48556,P20618,Q13309,Q15008,Q99436,Q06323 20
Transcriptional regulation by runx3 0.2948271730591298 0.1186850211011964 0.905524904091178 1.0 1.0 43 P25787,P49721,P51665,Q92530,P20618,P28070,O75832,Q99436,P42771 9
Global genome nucleotide excision repair gg ner 0.2653698696709637 0.1173468278721952 0.9065852180609204 1.0 1.0 47 P18858,P35251,Q9UGN5,P19447,Q13620,Q9H981,P49916,P61088,Q92889,P15927,Q9H9Q2,P41440,P28340,Q86WJ1,Q07864,P35244,P09874,P12004,Q99627,O75925 20
Regulation of hmox1 expression and activity 0.2310196267528548 0.1166427175808319 0.9071431850193332 1.0 1.0 48 P25787,P49721,Q13309,P67870,P51665,P20618,P19784,Q9BX63,P28070,O75832,Q99436 11
Esr mediated signaling 0.2302143365214898 0.1166231090157881 0.9071587243378724 1.0 1.0 48 P28482,Q15185,Q14683,O60341,Q8N3U4,O14646,O00459,P63218,P29353,P13984,P04792,Q9UQE7,P24928,Q15648,Q13547,P50750,O60216,O43815 18
Signaling by notch4 0.2734502986127841 0.1164826002729656 0.9072700751932896 1.0 1.0 45 P25787,Q9Y6A5,P49721,P51665,Q92530,P20618,P28070,O75832,Q99436 9
Regulated necrosis 0.2837410031250408 0.1164206714564135 0.9073191533352016 1.0 1.0 20 P41440,P09429 2
Cellular senescence 0.216179401233872 0.1163608566006904 0.9073665565142888 1.0 1.0 48 P17096,Q9HC52,Q9Y6J0 3
Nuclear envelope breakdown 0.2850575606396233 0.1161729007257429 0.9075155133960512 1.0 1.0 42 O15504,P35658,P53350,Q9BVL2,Q99986,Q86Y07,P14635 7
Sumoylation of ubiquitinylation proteins 0.2927983543517614 0.1158813490756113 0.9077465773835944 1.0 1.0 30 O15504,P35658,O75928,Q9BVL2,O75925 5
Myd88 independent tlr4 cascade 0.2893862737428112 0.115617406375065 0.9079557671308036 1.0 1.0 26 O15111,Q14738,Q02750,Q9UHD2,O14733,O43318,P09429,P61088,Q6SZW1,Q14790 10
Cdc42 gtpase cycle 0.2886399711555762 0.1154742273285988 0.9080692474189224 1.0 1.0 39 Q8N5V2,P14923,Q07960,P46940,Q9Y4F1,Q9NSV4,Q13017,Q9UQB8,Q9Y597 9
L1cam interactions 0.2630654796629268 0.1154393717398331 0.9080968734090712 1.0 1.0 45 O95782,P15311,O15020,Q02750,P67870,A0MZ66,P19784,Q96S59,P35241,P07942 10
Platelet homeostasis 0.2732303966349876 0.1153621391797378 0.9081580871145962 1.0 1.0 14 Q13362,Q13586,P63218 3
Degradation of gli1 by the proteasome 0.2832443293536851 0.1152634324150906 0.9082363218401066 1.0 1.0 41 Q99436,P25787,P25788,Q13200,P49721,Q99460,O00232,P51665,Q92530,P62333,P48556,P20618,P28070,O75832,Q15008,Q96J02,Q06323 17
Gpvi mediated activation cascade 0.262339224789022 0.1150406229333751 0.9084129233282549 1.0 1.0 8 P60953,P06241,P84095 3
Traf6 mediated nf kb activation 0.2614078687648311 0.1141872500353068 0.9090893587967748 1.0 1.0 8 P09429 1
Dna strand elongation 0.287021894747048 0.1133620525638189 0.9097435233961432 1.0 1.0 30 P18858,P49643,P35251,P51530,Q9BRX5,P49736,P49005,P41440,P35244,P49642,P27694,P12004,Q9Y248,P33991,P25205,P28340,P15927,P40938 18
Selective autophagy 0.2846511553227772 0.1127960345919401 0.9101922622176783 1.0 1.0 34 Q96FJ2,P54646,P50542,P61088 4
Rhobtb2 gtpase cycle 0.2779994567129935 0.1126739589151791 0.9102890475261464 1.0 1.0 20 O43396,P12814,Q9NYL9,Q8IYB3 4
Signaling by scf kit 0.2663956792530583 0.1125224343831435 0.9104091826340868 1.0 1.0 12 P63000,O00459,P62993,P42224,Q06124,P40763,P06241,O14757 8
Cellular response to hypoxia 0.2580490483996554 0.1124692922182595 0.910451316492966 1.0 1.0 42 P25787,P49721,P51665,P20618,P28070,Q99436 6
Defective cftr causes cystic fibrosis 0.1975289073857378 0.1119909712032245 0.91083056547094 1.0 1.0 44 P25787,P49721,P20618,P28070,Q99436,O94905 6
Rnd3 gtpase cycle 0.2750258006401742 0.1115648273651413 0.9111684615628588 1.0 1.0 19 P15924 1
Hedgehog ligand biogenesis 0.2261146287463367 0.1115105906698407 0.9112114678376916 1.0 1.0 43 P25787,P49721,P51665,P20618,P28070,Q99436 6
Runx1 regulates transcription of genes involved in differentiation of hscs 0.2525724046602009 0.1111340065615687 0.911510082423692 1.0 1.0 41 P25787,P49721,P51665,P20618,P28070,Q99436 6
Cdt1 association with the cdc6 orc origin complex 0.2582565492210963 0.1108744144616661 0.9117159347871826 1.0 1.0 40 P25787,P49721,P51665,P20618,P28070,Q99436 6
Mitochondrial trna aminoacylation 0.2730227134604684 0.1103373653389909 0.9121418249036736 1.0 1.0 19 Q96GW9,Q15046,Q5T160,P49590,P26640,Q9Y2Z4 6
Base excision repair 0.2752549030682682 0.1092301626714264 0.9130199370841076 1.0 1.0 31 P18858,P29372,P35251,Q9UGN5,Q07864,Q96T60,P41440,P35244,P09874,P12004,P28340,P15927,P49916,P27695 14
Cooperation of pdcl phlp1 and tric cct in g protein beta folding 0.2631208984648026 0.1089061436914557 0.9132769336715176 1.0 1.0 13 P63218,P67870 2
Myogenesis 0.2523745308038448 0.1078683075313897 0.914100157324429 1.0 1.0 7 O60271,P35221 2
Rmts methylate histone arginines 0.2703820455143579 0.1078121288748434 0.9141447215223252 1.0 1.0 21 O14497,Q86U86,Q92925,P51532,Q68CP9,Q96GM5,P11802 7
Synthesis of ip3 and ip4 in the cytosol 0.3469303829720954 0.1070212630351134 0.914772111168744 1.0 1.0 4 Q01968,P19174 2
Cytosolic trna aminoacylation 0.2696051393062957 0.1068638565785506 0.9148969872188292 1.0 1.0 23 P26639,Q13155,P07814,Q15046,P14868,P26640,P41250,P54577,O43324,P49591,P49588 11
Trna aminoacylation 0.2271419908619853 0.1067141234455094 0.9150157777023616 1.0 1.0 38 Q96GW9,Q13155,P26639,P07814,Q15031,Q15046,P14868,P26640,Q5T160,P49590,P54577,P41250,O43324,P49591,P49588,Q9Y2Z4 16
Signaling by braf and raf1 fusions 0.2684124991307181 0.1062016953445302 0.9154223258651852 1.0 1.0 26 Q02750,P46940,Q96PU8,P51114,O15164,P41240,O00203,O43252,Q9Y490,P18206,P32121,P36507 12
Hcmv late events 0.2014591860933146 0.1058547185676056 0.9156976214858384 1.0 1.0 38 Q99816,O15504,P35658,Q9BVL2,Q9HD42,P12270 6
Transcriptional regulation by small rnas 0.1934962962948991 0.1057190421515565 0.9158052715663304 1.0 1.0 38 O15504,P35658,Q9BVL2,O15397,P12270 5
Transport of mature mrnas derived from intronless transcripts 0.1915365111582656 0.1056920203947811 0.9158267116913146 1.0 1.0 38 O15504,P35658,Q6UN15,Q9P2I0,P52298,Q9BVL2,Q9C0J8,Q10570,P12270,Q8TEM1,P49790 11
Sumoylation of rna binding proteins 0.2449084890041417 0.10547143458785 0.9160017354381692 1.0 1.0 35 O15504,P35658,Q9HC52,Q9BVL2,Q14781 5
Fcgamma receptor fcgr dependent phagocytosis 0.2292227201161669 0.1049806235073522 0.9163911839506488 1.0 1.0 36 P28482,Q14185,P35579,P60953,P46108,O00459,Q96F07,P62993,O15144,Q9NZQ3,Q9Y6W5,O43865,P06241,P19174,Q9UQB8,P61160,Q05655,Q8WUW1 18
Viral messenger rna synthesis 0.1955115788963025 0.1037004068648248 0.9174071037656908 1.0 1.0 36 O15504,P35658,Q9BVL2,P12270,P13984 5
Eph ephrin signaling 0.1784012282856926 0.1034699750311216 0.9175899780207192 1.0 1.0 36 Q8N5V2,O95782,P35579,Q13464,O15144,Q00610,Q13177,P06241,O75116,P61160,P60953 11
Sumoylation of dna replication proteins 0.2132852764460791 0.1032153570900798 0.9177920518137196 1.0 1.0 35 O15504,P35658,Q96EE3,Q9BVL2,Q02880,O14965,P12270,Q53HL2,P12004,Q8TEM1,P46060,P49790,P11388 13
Ksrp khsrp binds and destabilizes mrna 0.2532327465328496 0.1031601284001873 0.9178358839544448 1.0 1.0 12 Q9Y2L1,Q13868,Q06265 3
Toll like receptor cascades 0.2430795517308651 0.1029753279864429 0.9179825522531522 1.0 1.0 32 O15111,Q14738,Q02750,Q9UHD2,Q15075,O14733,O43318,P09429,P61088,Q6SZW1,Q14790 11
Branched chain amino acid catabolism 0.2570297391494416 0.1029498639070354 0.9180027622385248 1.0 1.0 16 O14874 1
Cargo trafficking to the periciliary membrane 0.2563789956502469 0.1017163195792456 0.9189818481820232 1.0 1.0 19 Q96A65,Q8IYI6,Q8TAG9 3
Tryptophan catabolism 0.5648021828103731 0.1009510363581275 0.9195893288515824 1.0 1.0 2 P08195 1
Oncogenic mapk signaling 0.2253065381074085 0.1002766352532836 0.9201247063494506 1.0 1.0 31 Q02750,P46940,Q96PU8,P51114,O15164,P41240,O00203,O43252,Q9Y490,P18206,P32121,P36507 12
Nuclear pore complex npc disassembly 0.22662902937218 0.0995557940509974 0.920696990633207 1.0 1.0 30 Q9BVL2,O15504,P35658,P14635 4
Integration of energy metabolism 0.2461998221477737 0.0989403865163256 0.9211856024025222 1.0 1.0 24 Q14738,P46940,P63218,P54646,O00763 5
Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand 0.1803058804714347 0.0983152695057153 0.921681953610221 1.0 1.0 31 Q15185,P61163,Q9BUF5,P52907,Q9Y6G9,Q02790,P31689,P04350,Q14203,Q9UJW0,P31948,Q96FJ2 12
Formation of the early elongation complex 0.2468789912496144 0.0979320033433851 0.9219862871304104 1.0 1.0 19 P19447,P52298,P13984,O00267 4
Formation of tc ner pre incision complex 0.2135670448648207 0.0976222608551491 0.9222322473290704 1.0 1.0 29 P19447,P23193,P24928,O60306,Q9HCS7,Q9H9Q2 6
Processing of intronless pre mrnas 0.2457600871504162 0.0975498416173573 0.922289755043793 1.0 1.0 16 Q6UN15,Q9P2I0,P52298,Q9C0J8,Q10570,Q12996,P51003,Q86U42,Q8N684 9
Tysnd1 cleaves peroxisomal proteins 0.2666949204555988 0.0975074839344892 0.922323391232948 1.0 1.0 6 Q15067 1
Copi independent golgi to er retrograde traffic 0.2177508143511239 0.097070541081399 0.92267037516692 1.0 1.0 28 Q9NP72,Q9BUF5,P52907,Q9Y6G9,Q15042,Q9H2M9,P04350,P68402,Q14203,Q9UJW0,Q96FJ2 11
Darpp 32 events 0.2396644319683627 0.096954318105098 0.922762672338435 1.0 1.0 9 P62136 1
Interleukin 12 family signaling 0.1657516436990971 0.0960570317033386 0.9234752771754904 1.0 1.0 29 P52907 1
Ddx58 ifih1 mediated induction of interferon alpha beta 0.2382199155364926 0.0957523313035733 0.923717277432346 1.0 1.0 21 Q9UHD2,P09429,Q14790 3
Rhoj gtpase cycle 0.2246827285811454 0.0954452444326885 0.9239611802247072 1.0 1.0 25 P14923,Q07960,Q01968,Q9NSV4,Q13017,O00308 6
Sensory perception 0.1838119880187009 0.0953383098703088 0.924046114347679 1.0 1.0 28 P15311,P35579,P56545,P52907 4
B wich complex positively regulates rrna expression 0.2349086561609559 0.0941611384006173 0.9249811546340164 1.0 1.0 19 Q9UIG0,O75533,P62805,P49841,Q9NY93,Q9NR30,O60264,Q9BQG0,P19388,O00159 10
Signaling by fgfr 0.1690446731123403 0.0940279639170165 0.9250869431458306 1.0 1.0 27 P52298,P13984,P24928,P19174 4
Signaling by fgfr2 0.1690446731123402 0.0940279639170165 0.9250869431458306 1.0 1.0 27 P52298,P13984,P24928,P19174 4
Interleukin 12 signaling 0.192714481481319 0.093669797038756 0.9253714632323792 1.0 1.0 26 P52907 1
Listeria monocytogenes entry into host cells 0.2324990439995599 0.0930401981723485 0.9258716261846154 1.0 1.0 9 P62993,O60716,O75886,O14964,Q9NWH9 5
Gene and protein expression by jak stat signaling after interleukin 12 stimulation 0.2018757217307792 0.0923335844813257 0.926433005774472 1.0 1.0 24 P52907 1
Attenuation phase 0.2312179224148564 0.0918374663560498 0.9268271759837912 1.0 1.0 13 Q15185,Q02790,P04792,Q92598,O75190,Q00613 6
Activation of atr in response to replication stress 0.197956002540405 0.09116409757757 0.9273622021067792 1.0 1.0 23 O00311,O43913,P35244,Q13535,Q7L590,P33991,P15927,O60921,P40938,O14757 10
Erythropoietin activates ras 0.2990245309966073 0.0903177731815872 0.9280346969154364 1.0 1.0 5 P29353 1
Meiotic recombination 0.226724233226209 0.0902182362440453 0.928113792993968 1.0 1.0 13 Q92878,Q13472,P35244,P38398,P27694,P15927 6
Smooth muscle contraction 0.2259849760703738 0.0898484557494769 0.9284076417535174 1.0 1.0 12 P18206,P04083,Q9Y490,Q13177 4
Tp53 regulates transcription of cell cycle genes 0.2115690546428191 0.0893562919220429 0.9287987584564016 1.0 1.0 19 O14965,Q9C0C2,P14635,O75175,P06493 5
Erks are inactivated 0.2230625855550881 0.0890260020798351 0.9290612454916248 1.0 1.0 7 P28482,Q14738,P27361,P30154 4
Signaling by erbb2 0.2168602181498925 0.0885016095553179 0.9294780051204226 1.0 1.0 16 Q9UNE7,P29353,P06241,Q93034,P19174,Q05655,O60610 7
Ephb mediated forward signaling 0.2067041393665331 0.087258505348659 0.9304660361008998 1.0 1.0 17 Q13464,P06241,O75116,P61160,P60953 5
Vegfr2 mediated vascular permeability 0.2188994984042385 0.0871313789779485 0.9305670834090204 1.0 1.0 10 P14923,P35221 2
Aberrant regulation of mitotic exit in cancer due to rb1 defects 0.2130157697651383 0.0854880122103882 0.9318734254528712 1.0 1.0 11 Q9UJX6,Q9H1A4,Q13309 3
Transcriptional regulation by ventx 0.1889091113436908 0.0852014170514113 0.932101264035622 1.0 1.0 17 Q9UJX6,P42771,Q9H1A4,Q9H9B1 4
Hsf1 dependent transactivation 0.1666551141584031 0.0829211167278656 0.9339142631423684 1.0 1.0 16 Q15185,Q02790,P04792,Q92598,O75190 5
Negative regulators of ddx58 ifih1 signaling 0.2027813168413683 0.0824652538072272 0.9342767476402792 1.0 1.0 10 Q9UHD2,Q9UII4,Q7Z434,Q14258,Q96J02,P61086 6
Regulation of ifng signaling 0.2891489018077672 0.081764162447242 0.93483425484192 1.0 1.0 5 Q06124,O75925,P42224 3
Trafficking of glur2 containing ampa receptors 0.2033558414744258 0.0815077230887861 0.9350381831800476 1.0 1.0 7 P63010,O95782,P46459,Q96CW1 4
Negative regulation of met activity 0.1900912422546777 0.0799776607644565 0.9362550231729828 1.0 1.0 10 Q9NWH9,P17706,O14964,P62993 4
Interleukin 2 family signaling 0.2429116936155727 0.0799393896001656 0.9362854616861308 1.0 1.0 6 P29353,O00459,P42224 3
Dna methylation 0.3196833196833083 0.0750221579917748 0.9401970820431158 1.0 1.0 4 P26358,P62805,P16104 3
Shc1 events in erbb2 signaling 0.2782963974842899 0.0736645753153538 0.9412772869776316 1.0 1.0 5 P29353,Q05655 2
G beta gamma signalling through cdc42 0.3149108301127251 0.070409926693826 0.9438673905000892 1.0 1.0 4 P63218 1
Vegfr2 mediated cell proliferation 0.2666893031010807 0.0663960939199579 0.9470624799429944 1.0 1.0 5 Q05655,P19174 2
Pre notch processing in the endoplasmic reticulum 0.5350613915416151 0.0643025345560962 0.9487293353497784 1.0 1.0 2 Q04721 1
Signaling by leptin 0.5230559345156944 0.0521724484111959 0.95839128600867 1.0 1.0 2 Q06124 1
Interleukin 9 signaling 0.5230559345156944 0.0521724484111959 0.95839128600867 1.0 1.0 2 P42224 1
Interleukin 21 signaling 0.5230559345156944 0.0521724484111959 0.95839128600867 1.0 1.0 2 P42224 1
Activated ntrk2 signals through fyn 0.5004092769440711 0.0331250967611164 0.9735748294076771 1.0 1.0 2 P06241 1
Ntrk2 activates rac1 0.5004092769440711 0.0331250967611164 0.9735748294076771 1.0 1.0 2 P06241 1
Negative regulation of flt3 0.4995907230559402 0.0325249775425226 0.974053397365759 1.0 1.0 2 P41240 1