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Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
Metabolism of folate and pterines 0.8226189043789086 2.238363894363516 0.0251973345453482 0.9999999999999998 1.0 9 P41440,P34897,Q9H2D1 3
Methionine salvage pathway 0.9001271665685826 2.1841831298298966 0.0289487940662453 1.0 1.0 4 Q13126 1
Heme signaling 0.7793249417782546 2.0479765385166977 0.0405622983200935 1.0 1.0 10 P09601,O14867,Q09472,Q96EB6,Q15648,Q7Z5J4 6
Cytochrome c mediated apoptotic response 0.7649662415430056 1.996439591827504 0.0458860949250943 1.0 1.0 6 P98170,Q96GX9 2
Polb dependent long patch base excision repair 0.763751850496178 1.9858109504591757 0.0470543193983257 1.0 1.0 7 P27695,Q86W56 2
Regulation of runx1 expression and activity 0.8249054204380928 1.921503733649031 0.0546682321185034 1.0 1.0 5 Q00534,Q9UPQ9 2
Nrage signals death through jnk 0.7457305791431483 1.9018450184985456 0.057191418877901 1.0 1.0 8 P63000,Q92888,Q9Y5V3 3
Sulfur amino acid metabolism 0.743016232213529 1.8857936507051027 0.0593227668808085 1.0 1.0 12 Q13126,Q9UBX3,Q9Y6N5 3
Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux 0.7241376724351034 1.8102854040319991 0.070251539344448 1.0 1.0 7 Q9UPQ9,Q9HCE1 2
Formation of apoptosome 0.7968262097279589 1.808228055555274 0.0705710138183142 1.0 1.0 5 P98170,Q96GX9 2
Cytosolic iron sulfur cluster assembly 0.7244920713471603 1.8067766062580304 0.0707971176576442 1.0 1.0 8 O76071,P18074 2
Oncogene induced senescence 0.7063858737588109 1.7251370473194054 0.0845027774316315 1.0 1.0 8 Q00534,Q9UPQ9 2
Tgf beta receptor signaling in emt epithelial to mesenchymal transition 0.8751493428912763 1.681935628539572 0.0925813229570853 1.0 1.0 3 Q9Y624,Q8TEW0 2
Tp53 regulates transcription of cell death genes 0.6931633935301551 1.6711949528309145 0.094683176861636 1.0 1.0 7 P24386,P55212 2
Signaling by alk 0.6892574153165465 1.6609924535151213 0.0967149623488197 1.0 1.0 6 Q92769,Q09472,P19174 3
Small interfering rna sirna biogenesis 0.864905723080118 1.6434724593892982 0.1002852189715435 1.0 1.0 3 Q15631 1
Gpvi mediated activation cascade 0.7564318677044388 1.643344640243594 0.1003116471064364 1.0 1.0 5 P60953,P63000,P61586 3
Polo like kinase mediated events 0.6773110489200609 1.607222235568731 0.1080056259890014 1.0 1.0 6 O95067,Q09472,P53350 3
Smac xiap regulated apoptotic response 0.8552265901039129 1.607048972095536 0.1080436257407657 1.0 1.0 3 P98170 1
Synthesis of pc 0.7561421668067898 1.606547209342321 0.1081537309126006 1.0 1.0 4 P35790 1
Rrna processing in the mitochondrion 0.6747192110832053 1.59553084818337 0.1105935773761108 1.0 1.0 6 Q8WVM0,O15091,Q99714,Q9BQ52 4
Inactivation of csf3 g csf signaling 0.7412360234856165 1.5807952524272433 0.1139248604231664 1.0 1.0 5 Q15369 1
Degradation of cysteine and homocysteine 0.6670003448824983 1.560661291574379 0.1186036889326027 1.0 1.0 6 Q9Y6N5 1
Vitamin d calciferol metabolism 0.7430019559868803 1.5524310911055323 0.1205591089497108 1.0 1.0 4 P38435 1
Nuclear receptor transcription pathway 0.731953841845354 1.542465143934884 0.1229606018344924 1.0 1.0 5 Q15648 1
The phototransduction cascade 0.6630877999265152 1.534822796931828 0.1248273614400639 1.0 1.0 7 P53582,P50579,P49356,P49354,P62873 5
Nucleotide excision repair 0.3545474876463266 1.520616722448782 0.1283560478700371 1.0 1.0 59 Q96EZ8,Q9UBW8,Q9NR33,P18858,P18074,P49005,P41440,P62487,P35244,P12004,P18887,Q9Y2S7,Q9UNP9,Q09472,P35250,P25490,P35251,Q92905,Q92759,P49916,Q86WJ1,P15927 22
Phosphate bond hydrolysis by nudt proteins 0.8291517323775333 1.5085879440525125 0.1314041169850979 1.0 1.0 3 Q96DE0,P36639 2
Ptk6 regulates rho gtpases ras gtpase and map kinases 0.8278397950844512 1.503622524867247 0.1326785879763508 1.0 1.0 3 P63000 1
Transcriptional regulation by runx1 0.3781874680983354 1.5019811008209154 0.1331019897760423 1.0 1.0 73 P55036,O15047,Q13547,P17931,Q92793,Q9HCE1,Q09472,Q92925,Q00534,P67870,Q99873,Q14997,P49720,P49721,Q9UPQ9,P20618,Q68CP9 17
Synthesis of diphthamide eef2 0.7290099342923414 1.4946150542821297 0.135014934955564 1.0 1.0 4 Q9H2P9,P13639 2
Trna modification in the mitochondrion 0.6487195120410817 1.4778018652300289 0.1394608189947135 1.0 1.0 6 Q9Y606,O15091,O75648 3
Heme biosynthesis 0.7157324752537706 1.475282151089918 0.1401367030505078 1.0 1.0 5 P50336 1
Synthesis of udp n acetyl glucosamine 0.7237092414872253 1.4726657314978064 0.1408411911832559 1.0 1.0 4 Q9UJ70 1
Regulation of foxo transcriptional activity by acetylation 0.8175029868578236 1.4644676952438267 0.1430662034639098 1.0 1.0 3 Q96EB6,Q09472 2
Sulfide oxidation to sulfate 0.8160469162991217 1.4589479998110155 0.1445794204787591 1.0 1.0 3 Q9Y6N5 1
Carnitine metabolism 0.6442529213717941 1.4575043512119752 0.1449772111411706 1.0 1.0 6 P23786,Q13085,P54646,O43772 4
E2f enabled inhibition of pre replication complex formation 0.7197257624276486 1.456155453698522 0.1453496507613438 1.0 1.0 4 O43913 1
Tp53 regulates transcription of genes involved in g2 cell cycle arrest 0.6468592774368009 1.4475908374961592 0.1477315151531151 1.0 1.0 9 P30307,Q09472,P12004,O14965,Q99873 5
Sema4d mediated inhibition of cell attachment and migration 0.8053430834066837 1.418344181780745 0.1560903034733591 1.0 1.0 3 P63000 1
Dcc mediated attractive signaling 0.8023669512266982 1.4070469504878422 0.1594134671318086 1.0 1.0 3 P63000 1
Inactivation of cdc42 and rac1 0.8023669512266984 1.4070469504878422 0.1594134671318086 1.0 1.0 3 P63000 1
Switching of origins to a post replicative state 0.3397308790145323 1.3554948101670077 0.1752599609843685 1.0 1.0 59 Q9UBD5,Q14566,Q9UJX4,P49720,P24941,P33992,P20618,Q99741,P28072,P25786,Q13309,Q9UJX6,Q9UJX5,P55036,P28066,Q9H1A4,P61289,P25205,Q14997,P49721,O43913 21
Trna processing in the mitochondrion 0.6940387487410465 1.3494269689178549 0.1771998632430094 1.0 1.0 4 O15091,Q9BQ52 2
Regulation of mecp2 expression and activity 0.6228563814515747 1.3230957288330067 0.1858035449308253 1.0 1.0 14 P42858,Q9HCE1,Q92769,Q13555,P17612,Q9UPQ9 6
Tnfr1 induced nfkappab signaling pathway 0.6171722496711489 1.3101357932834763 0.1901499016882084 1.0 1.0 9 P63244,P98170,Q6GQQ9,Q12933,O15111 5
Bmal1 clock npas2 activates circadian gene expression 0.6827580931802859 1.3024493957427568 0.1927628061639574 1.0 1.0 4 Q15648 1
Nr1h2 and nr1h3 mediated signaling 0.6154192551362218 1.3020098941753957 0.1929130033361501 1.0 1.0 9 Q9UPQ9,Q9HCE1 2
Intraflagellar transport 0.6135341136504103 1.2804802953833538 0.2003762704102074 1.0 1.0 12 P63167 1
Recycling of eif2 gdp 0.6091677843247653 1.279957665646804 0.200560025086729 1.0 1.0 8 P41091,P20042,Q9NR50 3
Runx1 regulates transcription of genes involved in differentiation of myeloid cells 0.7686936064743782 1.2791020721238349 0.2008611140352476 1.0 1.0 3 P17931 1
Akt phosphorylates targets in the cytosol 0.6682787988742103 1.2777181506624111 0.2013488230167379 1.0 1.0 5 O15111 1
Resolution of abasic sites ap sites 0.5830156976373467 1.2672515471762684 0.2050653595542573 1.0 1.0 28 P56282,P18887,Q9Y2S7,P29372,P27695,P35250,P35244,P12004,P49916,Q86W56,P15927,P35251,Q9NR33,P18858,P49005,P41440 16
Runx1 regulates genes involved in megakaryocyte differentiation and platelet function 0.6107440671464407 1.2651625586214434 0.2058130610955655 1.0 1.0 14 O15047,Q9HCE1,Q09472,Q9UPQ9,Q99873 5
Detoxification of reactive oxygen species 0.6081913873231206 1.2628152119466642 0.2066555965368945 1.0 1.0 10 P00390,P30044 2
Termination of translesion dna synthesis 0.6023600617655294 1.2423109744599687 0.2141218477923203 1.0 1.0 19 Q9Y2S7,Q9UBZ9,Q14694,P35250,P35244,P12004,Q14258,P15927,P35251,Q9NR33,P49005,P41440 12
Role of phospholipids in phagocytosis 0.7560456012827841 1.2310469701584228 0.2183052974658279 1.0 1.0 3 P19174 1
Apoptotic factor mediated response 0.5937651028694949 1.217463354833775 0.2234279708163913 1.0 1.0 7 P98170,Q96GX9 2
Apex1 independent resolution of ap sites via the single nucleotide replacement pathway 0.7502986857825521 1.2092252907740384 0.2265763038966022 1.0 1.0 3 P18887,P49916 2
Rho gtpases activate ktn1 0.5933196772836674 1.206889525674188 0.2274746920197456 1.0 1.0 8 P84095,P60953,P63000,P61586 4
Gap filling dna repair synthesis and ligation in gg ner 0.593713561725577 1.1993838538868342 0.2303787228801201 1.0 1.0 19 P18887,Q9Y2S7,P35250,P35244,P12004,P49916,P15927,P35251,Q9NR33,P18858,P49005,P41440 12
Stat3 nuclear events downstream of alk signaling 0.6489844127145943 1.1972073139812778 0.2312257597940918 1.0 1.0 5 Q92769,Q09472 2
Mrna decay by 3 to 5 exoribonuclease 0.5949047944814448 1.191657533740223 0.233395555716368 1.0 1.0 16 Q9NQT5,Q9Y3B2,Q969T7,Q15024,Q9Y2L1 5
Biological oxidations 0.4488793054187999 1.1885101636375257 0.2346324779837614 1.0 1.0 47 P07099,Q9NUJ1,P78417 3
Translesion synthesis by y family dna polymerases bypasses lesions on dna template 0.5845985948433997 1.1797581687545806 0.2380964112658077 1.0 1.0 22 P55072,Q9Y2S7,Q9UBZ9,Q14694,P35250,P35244,P12004,Q14258,P15927,Q8TAT6,P35251,Q9NR33,P49005,P41440 14
Pcna dependent long patch base excision repair 0.5877018243316621 1.1695909379462186 0.2421656258870268 1.0 1.0 19 Q9Y2S7,P35250,P27695,P35244,P12004,P15927,P35251,Q9NR33,P18858,P49005,P41440 11
Dna damage bypass 0.5715488747857079 1.1671931543236007 0.2431323748397316 1.0 1.0 26 P55072,Q9Y2S7,Q9UBZ9,Q14694,Q9NZJ0,P35250,P35244,P12004,O94782,Q14258,P15927,Q8TAT6,P35251,Q9NR33,P49005,P41440 16
Branched chain amino acid catabolism 0.5884355413120168 1.1586631328926964 0.2465935239822596 1.0 1.0 14 P11182,Q99714,Q9HCC0,Q96RQ3,P31937,P21953 6
Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects 0.6475885871338156 1.155881302857519 0.247729711370102 1.0 1.0 4 Q00534 1
Trna processing 0.3284189206642139 1.1539867405898063 0.2485056050478329 1.0 1.0 63 P55735,Q96FX7,Q9Y3I0,Q2VPK5,Q99575,Q99714,Q9Y606,Q9UKX7,Q9BQ52,Q7Z3B4,Q9H974,O60294,Q52LJ0,Q9UBP6,P78406,O15091,O75648,Q9UET6 18
Translesion synthesis by polk 0.5853559808664057 1.1514720785006447 0.2495380757032101 1.0 1.0 11 P35244,Q9UBZ9,P41440,P15927 4
Conversion from apc c cdc20 to apc c cdh1 in late anaphase 0.5806982448174087 1.1487649456559823 0.2506529175282834 1.0 1.0 8 Q9UJX6,Q9UJX5,Q9UJX4 3
Long term potentiation 0.6359011057462072 1.1426555476752736 0.2531816328279981 1.0 1.0 5 Q92796,Q13555 2
Ras activation upon ca2 influx through nmda receptor 0.6359011057462072 1.1426555476752736 0.2531816328279981 1.0 1.0 5 Q92796,Q13555 2
Unblocking of nmda receptors glutamate binding and activation 0.6359011057462072 1.1426555476752736 0.2531816328279981 1.0 1.0 5 Q92796,Q13555 2
Basigin interactions 0.5759426795687752 1.1357729017537312 0.2560516208891872 1.0 1.0 7 P53985 1
Resolution of ap sites via the multiple nucleotide patch replacement pathway 0.5734536914457412 1.1341731832798143 0.2567219103923999 1.0 1.0 23 Q9Y2S7,P35250,P27695,P35244,P12004,Q86W56,P15927,P35251,Q9NR33,P18858,P49005,P41440 12
Pten regulation 0.3328397374776913 1.126798197135893 0.2598278129530955 1.0 1.0 67 P98170,P55036,Q9HCE1,Q8WXI9,Q14997,P49721,Q9UPQ9,P20618,Q86YP4 9
Synaptic adhesion like molecules 0.5716886162145636 1.1163054486705268 0.2642914101209388 1.0 1.0 7 P41440 1
Diseases of mitotic cell cycle 0.5784954235488079 1.1113736931403948 0.266407530944484 1.0 1.0 14 Q9UER7,Q9UJX4,Q00534,Q13309,P24941,Q9UJX6,Q9UJX5 7
Base excision repair 0.541323006363197 1.105685900784445 0.2688624946730957 1.0 1.0 31 P56282,P18887,Q9Y2S7,P29372,P27695,P35250,P35244,P12004,P49916,Q86W56,P15927,P35251,Q9NR33,P18858,P49005,P41440 16
Cdc6 association with the orc origin complex 0.7221651822237808 1.102640975037183 0.2701831086981636 1.0 1.0 3 O43913 1
Map3k8 tpl2 dependent mapk1 3 activation 0.565888301684887 1.1000413560105593 0.2713141033087534 1.0 1.0 6 O15111 1
Sema3a plexin repulsion signaling by inhibiting integrin adhesion 0.6336018907772789 1.0976817578268523 0.2723434781608378 1.0 1.0 4 P63000 1
Purine catabolism 0.566542564779088 1.0927794618685396 0.2744906412148911 1.0 1.0 7 Q96DE0 1
Displacement of dna glycosylase by apex1 0.7176654593824646 1.0856480792195335 0.277634719766556 1.0 1.0 3 P27695 1
Neurexins and neuroligins 0.5673766543712859 1.07971227799238 0.2802703247078688 1.0 1.0 9 Q92796,Q96HC4 2
Purine salvage 0.5610097709506997 1.077846360157476 0.2811023265119425 1.0 1.0 6 P55263,Q01433 2
Transcriptional regulation of white adipocyte differentiation 0.5685158866518447 1.0749186584579795 0.2824111475527489 1.0 1.0 19 Q71SY5,Q13503 2
Protein methylation 0.5598726517962145 1.0623325373399806 0.2880847482419439 1.0 1.0 7 P15880,P55072,P13639 3
Formation of xylulose 5 phosphate 0.7081839904420488 1.0499096935606829 0.2937596343954576 1.0 1.0 3 Q7Z4W1,Q00796 2
Transport of inorganic cations anions and amino acids oligopeptides 0.5586474073473788 1.047561599209089 0.2948406376261485 1.0 1.0 8 Q70HW3 1
Pre notch expression and processing 0.5628864717245842 1.0424353211519874 0.2972098977636839 1.0 1.0 12 P16615,Q09472,Q9UPQ9,Q9HCE1 4
Advanced glycosylation endproduct receptor signaling 0.5569929763289747 1.0399947619776728 0.2983423342223861 1.0 1.0 8 P09429,P17931 2
Response of eif2ak1 hri to heme deficiency 0.6162753028009176 1.0257951098522473 0.3049881716031448 1.0 1.0 4 P20042 1
Phase i functionalization of compounds 0.5603757182842999 1.024892721296037 0.3054138094141179 1.0 1.0 15 P07099 1
Regulation of lipid metabolism by pparalpha 0.5410839083719139 1.022698752251073 0.3064503015384123 1.0 1.0 27 Q71SY5,Q9Y2X0,P37268,Q15067,Q13503 5
Dna replication pre initiation 0.3159492206513948 1.0218238650790392 0.3068642719447485 1.0 1.0 63 P55036,Q9UBD5,Q9NR33,P35244,Q14997,P15927,P49721,P24941,O43913,P20618 10
Gamma carboxylation hypusine formation and arylsulfatase activation 0.5563400995866048 1.016419231278281 0.3094297915319497 1.0 1.0 11 Q9BQC3,Q9H2P9,P38435,P13639,P63241 5
G1 s specific transcription 0.5518245500794255 1.0082637815369764 0.3133278454650281 1.0 1.0 9 Q99741,Q13547,P12004,P04183,P00374 5
Traf3 dependent irf activation pathway 0.5450751093854325 1.005570256547069 0.3146223376083124 1.0 1.0 6 Q09472,Q14258 2
Selenoamino acid metabolism 0.3607889561725393 1.0038548891976056 0.3154485629161212 1.0 1.0 91 P62280,P36578,P25398,P08708,P15880,P46776,P46782,P61513,P00390,O95340,Q02543,Q12904,Q13155,P32969,P05388,P62753,P50914,P57772,P62829,P18621,P27635,P08865,P62917,P62888,P54136,Q16881,P61247,P62266,P62249,P62841,P62899 31
Activation of ampk downstream of nmdars 0.5463598722295877 1.0008512465662374 0.3168987297031389 1.0 1.0 7 P54619,P54646,P04350 3
Transcriptional regulation by mecp2 0.5522100584724973 1.0006884114146064 0.3169774717177986 1.0 1.0 20 P42858,Q9HCE1,Q92769,Q14353,Q13555,P17612,Q9UPQ9 7
Met activates rap1 and rac1 0.5990330826890946 0.9896144315175364 0.3223626134235218 1.0 1.0 5 P46109 1
Plasma lipoprotein assembly 0.6917444022944059 0.9882101938952242 0.3230497167486277 1.0 1.0 3 P17612 1
Maturation of sars cov 2 nucleoprotein 0.5974336936796933 0.9830126673611712 0.3256012042296616 1.0 1.0 5 Q99873 1
Mapk6 mapk4 signaling 0.385789706951578 0.9771173139416166 0.3285110770674122 1.0 1.0 51 P55036,P04792,P28066,Q9HCE1,P63000,P60953,Q14997,P49720,P49721,P17612,Q9UPQ9,P20618 12
Recognition of dna damage by pcna containing replication complex 0.5472838125363603 0.9765322133406732 0.3288007924892393 1.0 1.0 20 Q9Y2S7,Q9NZJ0,P35250,P35244,P12004,O94782,P15927,P35251,Q9NR33,P49005,P41440 11
Pyroptosis 0.5879046896523287 0.9437710841984656 0.3452866399706951 1.0 1.0 5 Q8WUX9 1
Diseases of immune system 0.5957631887751065 0.9411813671645926 0.3466119236240828 1.0 1.0 4 O15111 1
Netrin 1 signaling 0.538476534281443 0.9401509654443084 0.3471401295658709 1.0 1.0 10 P19174,P60953,P63000,Q16512 4
Nf kb activation through fadd rip 1 pathway mediated by caspase 8 and 10 0.5328679028291619 0.9398204733524492 0.3473096553106156 1.0 1.0 7 O15111 1
Assembly of the orc complex at the origin of replication 0.5293995373272727 0.9349194025476372 0.3498298371022621 1.0 1.0 6 O43913 1
Nucleotide catabolism 0.5314156796307359 0.9237160922531252 0.3556341514436414 1.0 1.0 8 Q96DE0 1
Formation of the cornified envelope 0.5268420063965424 0.923446637016768 0.355774497282781 1.0 1.0 6 Q02487,P04632 2
Keratinization 0.5268420063965424 0.923446637016768 0.355774497282781 1.0 1.0 6 Q02487,P04632 2
Metabolism of water soluble vitamins and cofactors 0.4618293590791791 0.9190615853012596 0.358063360715942 1.0 1.0 40 Q05932,P34896,Q9NQX3,Q9HCC0,P11498,Q8NFF5,P78417,Q96RQ3,P34897,P05165,Q9H2D1,P00374,P41440 13
Phosphorylation of the apc c 0.5333706437288952 0.91076284647465 0.3624203424424217 1.0 1.0 11 P53350,Q9H1A4,Q9UJX4,Q9UJX6,Q9UJX5 5
Fanconi anemia pathway 0.5303762218932541 0.9105847525113856 0.3625142073464289 1.0 1.0 9 O94782,P15927 2
Circadian clock 0.5352154185661689 0.907857352301792 0.3639535924109522 1.0 1.0 14 Q09472,P62136,Q96EB6,Q15648,P62140,Q7Z5J4 6
Rora activates gene expression 0.5775342709653633 0.9012679117375196 0.3674458904875253 1.0 1.0 5 Q09472,Q15648 2
Tight junction interactions 0.909823828008362 0.8998113469323645 0.3682206548136695 1.0 1.0 2 Q9Y624 1
Competing endogenous rnas cernas regulate pten translation 0.9026575097043772 0.8763455798534242 0.3808421933133701 1.0 1.0 2 Q9UPQ9 1
Regulation of pten mrna translation 0.9026575097043772 0.8763455798534242 0.3808421933133701 1.0 1.0 2 Q9UPQ9 1
Tak1 activates nfkb by phosphorylation and activation of ikks complex 0.5166165685564174 0.866943877254901 0.3859727609143717 1.0 1.0 7 O15111 1
G alpha 12 13 signalling events 0.5228051556235278 0.8627173785314391 0.3882928750424923 1.0 1.0 11 P61586,Q9H8V3,Q92888,P62873 4
Response of eif2ak4 gcn2 to amino acid deficiency 0.3247681589504223 0.8581030165576107 0.3908355818117592 1.0 1.0 78 P62280,P36578,P41091,P25398,P08708,P15880,P46776,P46782,P61513,Q02543,P32969,P05388,P62753,P50914,P62829,P18621,P27635,P08865,P62917,P62888,P61247,P62266,P62249,P20042,P62841,P62899 26
Translesion synthesis by polh 0.5236365314856238 0.8573016909007355 0.3912781742770912 1.0 1.0 13 P55072,P35250,P35244,P15927,Q8TAT6,P35251,P41440 7
Assembly and cell surface presentation of nmda receptors 0.5195964131036995 0.8482104736164253 0.3963207653605831 1.0 1.0 11 Q92796,Q13557,Q13555,Q12959,P04350 5
Cell death signalling via nrage nrif and nade 0.5192621188386455 0.8467015461059737 0.3971614967341004 1.0 1.0 11 P63000,Q92888,Q9Y5V3 3
Apc c cdc20 mediated degradation of cyclin b 0.517307630935008 0.8442616598315176 0.3985232056074903 1.0 1.0 10 Q9H1A4,Q9UJX6,Q9UJX5,Q9UJX4 4
Downregulation of tgf beta receptor signaling 0.5085009126164562 0.8308764612308415 0.406043422412472 1.0 1.0 7 P62136 1
Vegfr2 mediated cell proliferation 0.6451770027680684 0.8161839208729974 0.4143949517094705 1.0 1.0 3 P19174 1
Dual incision in gg ner 0.5059294841024551 0.8154562153495769 0.41481121747419 1.0 1.0 25 Q9Y2S7,P35250,Q92759,P35244,P12004,Q86WJ1,P15927,P35251,Q9NR33,P18074,P49005,P41440 12
Traf6 mediated irf7 activation 0.5036531802142299 0.8094535041562743 0.4182543370716671 1.0 1.0 7 Q09472,Q14258,Q92793,Q12933 4
Constitutive signaling by akt1 e17k in cancer 0.5025280025841157 0.8044950833963281 0.4211111076816523 1.0 1.0 7 O15111 1
Hcmv infection 0.3176229409293155 0.801032794170464 0.4231126609139821 1.0 1.0 56 Q99816,P55735,O43237,Q9BRG1,Q9UER7,Q96FJ2,Q7Z3B4,Q8WUX9,P63167,P78406 10
Mapk1 erk2 activation 0.6397881282556273 0.7966330228618957 0.4256641927832894 1.0 1.0 3 P36507 1
Tp53 regulates transcription of several additional cell death genes whose specific roles in p53 dependent apoptosis remain uncertain 0.5595546422020852 0.7939734406635982 0.4272108933043821 1.0 1.0 4 P24386 1
Notch2 intracellular domain regulates transcription 0.6379928315412097 0.7901399096237335 0.4294460645650799 1.0 1.0 3 Q09472,Q04721 2
Sirt1 negatively regulates rrna expression 0.5583695643946582 0.7892187848009004 0.4299841446765158 1.0 1.0 4 Q96EB6,O43159 2
Negative regulation of nmda receptor mediated neuronal transmission 0.5005953010163549 0.7861951062502568 0.4317531926610529 1.0 1.0 8 Q92796,Q13555 2
Cell cell junction organization 0.502152838522542 0.7843450293131905 0.4328376842318642 1.0 1.0 9 Q9BY67,Q9Y624 2
Alpha linolenic omega3 and linoleic omega6 acid metabolism 0.495589922703217 0.7740440842488177 0.4389047220152999 1.0 1.0 7 P09110,Q15067,O14734 3
Dna methylation 0.5528356661668427 0.7670811788165226 0.443033251458647 1.0 1.0 4 P26358,Q96T88 2
Signaling by ptk6 0.4998843433447442 0.7601157676621496 0.447185388400074 1.0 1.0 11 Q07666,P24941,P63000 3
Cytosolic sulfonation of small molecules 0.5414212874352178 0.7555380369199741 0.4499262186157777 1.0 1.0 5 O95340 1
Role of abl in robo slit signaling 0.547953391096518 0.7476439266779958 0.4546749616470924 1.0 1.0 4 O75122,Q01518,Q7Z460 3
Transcription coupled nucleotide excision repair tc ner 0.3855195253238789 0.7338113959570278 0.4630636941087864 1.0 1.0 47 Q9UBW8,Q9NR33,P18858,P18074,P49005,P41440,P62487,P35244,P12004,P18887,Q9Y2S7,Q9UNP9,Q09472,P35250,P35251,Q92905,Q92759,P49916,P15927 19
Dscam interactions 0.6200206400033278 0.7257519733543968 0.4679908338488132 1.0 1.0 3 P63000 1
Activation of rac1 0.5423181666218588 0.7253260699358502 0.4682520159347505 1.0 1.0 4 P63000 1
Regulated necrosis 0.4948848149482537 0.7235810099181333 0.4693230033816458 1.0 1.0 19 P98170,P41440,Q8WUX9 3
Perk regulates gene expression 0.4945943623315012 0.7193455883065346 0.4719280133979342 1.0 1.0 17 Q9NQT5,Q92945,Q15024,P20042,Q9Y2L1,Q9Y3B2 6
Dual incision in tc ner 0.4531811909157146 0.7159975992568692 0.4739928313103454 1.0 1.0 35 Q9Y2S7,P62487,Q9UNP9,Q09472,P35250,Q92759,P35244,P12004,P15927,P35251,Q9NR33,P18074,P49005,P41440 14
Cholesterol biosynthesis 0.4914315794881581 0.7059491497624768 0.4802197607262672 1.0 1.0 18 Q9BWD1,Q16850,Q15392,P37268 4
Apc cdc20 mediated degradation of nek2a 0.4875030190759616 0.7058465701196134 0.4802835574765607 1.0 1.0 11 Q9UJX6,Q9UJX5,Q9UJX4 3
Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components 0.4875030190759616 0.7058465701196134 0.4802835574765607 1.0 1.0 11 Q9UJX6,Q9UJX5,Q9UJX4 3
Synthesis of dna 0.3206615346890288 0.7037206350000329 0.481606767143798 1.0 1.0 86 Q9UBD5,Q14566,Q9UJX4,P49720,P24941,P33992,P20618,Q9NR33,P18858,P49005,P41440,P35244,P12004,P56282,Q9Y2S7,Q99741,P35250,P28072,P25786,Q13309,P35251,Q9UJX6,Q9UJX5,P55036,P28066,Q9H1A4,P61289,P25205,Q14997,P15927,P49721,P49643,O43913 33
Oxidative stress induced senescence 0.4902980471052645 0.7008478609599491 0.4833979657676899 1.0 1.0 18 Q00534,Q9UPQ9,Q9HCE1 3
Beta catenin independent wnt signaling 0.2776995093485365 0.6930111616226325 0.4883025469441173 1.0 1.0 60 P55036,P61586,O94973,Q9HCE1,P09471,P63000,Q14997,P49721,Q9UPQ9,P20618 10
Gap junction assembly 0.5254034668260548 0.6924312685441597 0.488666534994413 1.0 1.0 5 Q9BVA1,P68371,P04350,Q13885 4
Transport of connexons to the plasma membrane 0.5254034668260548 0.6924312685441597 0.488666534994413 1.0 1.0 5 Q9BVA1,P68371,P04350,Q13885 4
Metabolism of porphyrins 0.480666244237055 0.690762346062183 0.4897149019915296 1.0 1.0 9 P36551,P50336 2
Cellular response to starvation 0.324603368284003 0.684314410755016 0.4937766490668296 1.0 1.0 90 P55735,P62280,P36578,P41091,P25398,P08708,P15880,P46776,P46782,P61513,Q9NXC5,Q02543,P32969,P05388,P62753,P50914,P62829,P18621,P27635,P08865,Q9Y5K8,P62917,P62888,P61247,P62266,P62249,P20042,P62841,P62899 29
Phosphorylation of emi1 0.6065686305348267 0.6783788997779585 0.4975314840879599 1.0 1.0 3 P53350 1
Transcription of e2f targets under negative control by dream complex 0.5302974073113602 0.6781796271657413 0.4976578082180318 1.0 1.0 4 P12004,Q13547 2
Oas antiviral response 0.6041253290781096 0.6698588939129044 0.5029477459433562 1.0 1.0 3 Q6L8Q7 1
Kinesins 0.4802307848821089 0.6689256271600562 0.5035429216676017 1.0 1.0 22 Q9H0B6,O00139,Q9H0H5,Q96Q89,Q9BVA1,Q99661,Q9BW19,O60333,O95235,O95239,Q12756,Q14807,P04350 13
P75ntr negatively regulates cell cycle via sc1 0.8366676619886546 0.6674433491666175 0.5044889842387743 1.0 1.0 2 Q92769 1
Ephrin signaling 0.5253880104343863 0.6591221378984421 0.509817340846906 1.0 1.0 4 P63000 1
Ca2 pathway 0.4750202431848703 0.658881566664866 0.5099718237082747 1.0 1.0 10 Q9UPQ9,P09471,Q9HCE1 3
Traf6 mediated nf kb activation 0.4706106140383499 0.6566995128592592 0.5113741477409728 1.0 1.0 8 O15111 1
Regulation of tp53 activity 0.2817086426347315 0.6558990817801468 0.5118890590548437 1.0 1.0 58 P54646,O14757,Q9UER7,Q9ULW0,Q09472,P35250,Q92547,P35244,Q92769,Q8WXI9,P15927,P24941,P67870,Q86YP4 14
Intracellular signaling by second messengers 0.3266905968576988 0.6506341513795624 0.5152826793164313 1.0 1.0 94 P55036,P98170,Q9HCE1,P49815,P19174,P84095,P63000,Q92769,Q8WXI9,P67870,Q14997,P49721,Q13555,P17612,Q9UPQ9,P20618,O15111,Q86YP4 18
Ros and rns production in phagocytes 0.4686320473092895 0.6483506503040936 0.5167581811483855 1.0 1.0 8 Q93050 1
Aberrant regulation of mitotic exit in cancer due to rb1 defects 0.4723852256054956 0.6476949803529626 0.5171822515111715 1.0 1.0 10 Q9UJX6,Q9UJX5,Q13309,Q9UJX4 4
Tgf beta receptor signaling activates smads 0.4722376248112987 0.6470698740148356 0.5175867218519536 1.0 1.0 10 Q9UNE7,P61081,Q96PU5,Q13485,P62136,P62140 6
Activation of atr in response to replication stress 0.4750379516157308 0.6453669511569586 0.518689415063412 1.0 1.0 22 O14757,Q9UBD5,O43913,P35244,P15927,P24941,P33992 7
Factors involved in megakaryocyte development and platelet production 0.3497309314340357 0.6452698240610536 0.5187523443162365 1.0 1.0 50 Q9H0B6,P17612,P24941,Q13547,O00139,P63000,Q99661,Q9UKL0,Q12756,Q92667,Q92769,Q9BW19,O60333,P47755,O95235,Q14807,P20339,Q9H0H5,P60953,P17252 20
Beta oxidation of lauroyl coa to decanoyl coa coa 0.5195771237445341 0.636726814055413 0.5243028044911644 1.0 1.0 4 P55084,P30084 2
Beta oxidation of hexanoyl coa to butanoyl coa 0.5195771237445341 0.636726814055413 0.5243028044911644 1.0 1.0 4 P55084,P30084 2
Metabolism of steroids 0.3560299132075818 0.6365206474360864 0.524437127636949 1.0 1.0 49 Q9BWD1,P37268,Q15392,Q16850,P38435 5
Tysnd1 cleaves peroxisomal proteins 0.5093444263486546 0.6304140085605474 0.5284237478552858 1.0 1.0 5 P09110,Q15067 2
Ephb mediated forward signaling 0.4714406795374595 0.6226500017609218 0.5335145452938186 1.0 1.0 14 P61586,P61158,P61160,P63000,P60953 5
Triglyceride metabolism 0.4596608934363086 0.6205486642263527 0.5348966254617209 1.0 1.0 7 P62140,P62136 2
Triglyceride catabolism 0.4596608934363086 0.6205486642263527 0.5348966254617209 1.0 1.0 7 P62140,P62136 2
Mitotic g1 phase and g1 s transition 0.2982207768631132 0.6190363602324442 0.5358924059104302 1.0 1.0 78 P55036,Q9UBD5,P20618,P35244,Q00534,P04183,P49721,P15927,P00374,P24941,O43913,Q9NR33 12
Sema4d in semaphorin signaling 0.4601286142091324 0.6127935579122222 0.5400128510143398 1.0 1.0 8 P63000 1
Ercc6 csb and ehmt2 g9a positively regulate rrna expression 0.468165151169427 0.6125730898266438 0.5401586561679721 1.0 1.0 13 Q92769,Q8WXI9,Q86YP4 3
Signaling by scf kit 0.461521861894512 0.6098677922748356 0.5419493893761196 1.0 1.0 9 O14757 1
Regulation of gene expression by hypoxia inducible factor 0.8172588832487335 0.6091337687599786 0.5424357761299543 1.0 1.0 2 Q09472 1
Foxo mediated transcription of cell death genes 0.8172588832487335 0.6091337687599786 0.5424357761299543 1.0 1.0 2 Q09472 1
Activation of the tfap2 ap 2 family of transcription factors 0.8172588832487335 0.6091337687599786 0.5424357761299543 1.0 1.0 2 Q09472 1
Purine ribonucleoside monophosphate biosynthesis 0.4625694588787544 0.606490370011697 0.544189175150795 1.0 1.0 10 P30520,P20839,P49915,P31939,P12268 5
Global genome nucleotide excision repair gg ner 0.3782179980534252 0.6014557580055223 0.5475364706606878 1.0 1.0 45 Q96EZ8,Q9UBW8,Q9NR33,P18858,P18074,P49005,P41440,P35244,P12004,P18887,Q9Y2S7,P35250,P25490,P35251,Q92905,Q92759,P49916,Q86WJ1,P15927 19
Complex i biogenesis 0.4561542135495859 0.598688569976655 0.5493805806947214 1.0 1.0 27 Q9BU61,P49821,Q7L592,O43678,O75380,Q9BQ95,Q9P0J0 7
Gluconeogenesis 0.4658043035859854 0.5966165859798592 0.5507633950788686 1.0 1.0 20 P53007,P00558,P04406,P09972,Q16822,P60174,P04075,Q9UBX3,P11498 9
Mrna splicing minor pathway 0.4413371335700736 0.5959681223532024 0.551196522631741 1.0 1.0 32 Q96DI7,Q9BWJ5,Q09161,P55769,Q9Y333 5
Ion homeostasis 0.4625084574703564 0.593695838161474 0.5527155671691419 1.0 1.0 12 P54709,Q13555,Q13557,P16615,P17612 5
Activation of gene expression by srebf srebp 0.464269387206018 0.587859912183989 0.5566263259683606 1.0 1.0 19 Q16850,P37268 2
Eukaryotic translation elongation 0.2941783343783698 0.5858778573770479 0.5579575982449827 1.0 1.0 78 P62280,P36578,P25398,P13639,P08708,P15880,P46776,P46782,P61513,Q02543,P32969,P05388,P62753,P50914,P62829,P18621,P27635,P08865,P62917,P62888,Q05639,P61247,P62266,P62249,P62841,P62899 26
Synthesis of ip3 and ip4 in the cytosol 0.5046999035071054 0.5802675070428671 0.5617342357737738 1.0 1.0 4 P19174 1
Signaling by csf3 g csf 0.4474248530873236 0.5702978096113007 0.56847572627883 1.0 1.0 7 Q15369 1
Pyruvate metabolism 0.4593581249807221 0.5689977072614728 0.5693576958771809 1.0 1.0 15 P53985 1
Condensation of prometaphase chromosomes 0.4530319648608368 0.5672190055569297 0.5705653970850917 1.0 1.0 10 O95067 1
Loss of function of mecp2 in rett syndrome 0.4458932415419048 0.564094942333301 0.5726895199220259 1.0 1.0 7 P17612,Q13547 2
Ras processing 0.4917064580825406 0.5640393344578558 0.5727273629822969 1.0 1.0 5 P49356,P49354 2
C type lectin receptors clrs 0.2797348557070049 0.5631693583585131 0.5733195659550154 1.0 1.0 57 P49720,P17612,P20618,O15111,P61081,Q8TBC4,Q09472,P28072,P25786,O14920,P28066,P55036,Q92793,O95999,Q16512,P61289,Q14997,P17252,P49721 19
Trna modification in the nucleus and cytosol 0.457399090062889 0.5586736810148946 0.5763844444914175 1.0 1.0 19 Q96FX7,Q2VPK5,Q9Y606,O60294,Q9H974,Q9UBP6,Q9UET6 7
Regulation of bach1 activity 0.4970807479067638 0.5518928202978878 0.5810217877159138 1.0 1.0 4 O14867 1
Signal transduction by l1 0.4477869969135445 0.5459730538987109 0.5850844599018614 1.0 1.0 10 P67870,P63000,Q16512,P36507 4
Apc c mediated degradation of cell cycle proteins 0.2684483463763026 0.5458222344648113 0.5851881378919828 1.0 1.0 58 Q99436,Q9UJX4,O14965,P49720,P24941,P20618,P28070,P53350,P28072,P25786,Q13309,Q9UJX6,Q9UJX5,P55036,P28066,Q9H1A4,P61289,Q14997,P49721 19
Acyl chain remodeling of cl 0.5666069295101436 0.5428876974690134 0.5872071269473687 1.0 1.0 3 P40939,P55084 2
Rhov gtpase cycle 0.4526432847770498 0.5413557037500303 0.5882624327451003 1.0 1.0 15 Q9NNW5,Q7Z6J0,Q96KM6,P60953,O43396,Q03001 6
Gene silencing by rna 0.3611605491731526 0.539863838366263 0.5892909378482045 1.0 1.0 46 P55735,Q9Y2W6,Q9UKX7,Q15631,Q7Z3B4,O75569,Q9UPQ9,P78406 8
G protein beta gamma signalling 0.4385621845199808 0.5346942249243404 0.5928613155628244 1.0 1.0 7 P60953,P61586,P62873 3
Pi3k akt signaling in cancer 0.447378164201084 0.526995811602745 0.5981964970511915 1.0 1.0 13 P63000,O15111,P49815 3
Neddylation 0.2827596896838719 0.5206982074758992 0.6025770233090704 1.0 1.0 76 P55036,Q96GG9,Q9Y5A7,Q9UBW8,Q9Y6G5,Q15369,Q15345,Q14997,P49721,Q15370,P20618 11
Energy dependent regulation of mtor by lkb1 ampk 0.4346554829059189 0.5192308915081791 0.6035997393515353 1.0 1.0 7 P54646 1
Ion transport by p type atpases 0.4407669089032691 0.5179557224062712 0.6044891625549345 1.0 1.0 10 P16615,P54709,Q13555,Q13557 4
Fc epsilon receptor fceri signaling 0.2734766078875233 0.5157787009846296 0.6060089800635953 1.0 1.0 57 P55036,P19174,O95999,P63000,Q14997,P49721,P20618,O15111 8
Ripk1 mediated regulated necrosis 0.4447196152386722 0.5124175220969298 0.6083588303982936 1.0 1.0 14 P41440 1
Hdacs deacetylate histones 0.4454026791039162 0.5120987021122009 0.6085819328498172 1.0 1.0 15 Q92769,O75446,Q8WXI9,Q86YP4 4
Sumoylation of dna methylation proteins 0.5568808475961009 0.5113380255720208 0.6091143828566856 1.0 1.0 3 P26358 1
Srp dependent cotranslational protein targeting to membrane 0.3021602350572595 0.507479352204072 0.611818520388218 1.0 1.0 90 P09132,P62280,P36578,P25398,P08708,P15880,P46776,P46782,P61513,Q02543,P32969,P05388,P62753,P50914,P62829,P18621,P27635,P08865,P49458,P08240,P62917,P62888,P61247,P62266,P62249,P62841,P62899 27
Metabolism of vitamins and cofactors 0.3422685746361606 0.5074636620579797 0.6118295267985439 1.0 1.0 48 Q05932,P34896,Q9NQX3,Q9HCC0,P11498,Q8NFF5,P78417,Q96RQ3,Q8TC12,P34897,P05165,Q9H2D1,P00374,Q86YH6,P41440 15
Cellular response to chemical stress 0.2817642525925329 0.5017849629505852 0.6158187916795881 1.0 1.0 77 P55036,O14867,P14854,Q16881,P00390,P67870,Q15648,Q14997,P30044,P49721,P20618 11
Beta oxidation of very long chain fatty acids 0.4258662763567802 0.4950946898092572 0.6205332820202043 1.0 1.0 6 P09110,Q15067,O14734 3
Ret signaling 0.4275470225440312 0.4914816288906345 0.6230858424478529 1.0 1.0 7 P19174,P17612,P17252,Q13164 4
Atf4 activates genes in response to endoplasmic reticulum stress 0.4388532929360954 0.4892355112742104 0.6246749712550579 1.0 1.0 14 Q9NQT5,Q9Y3B2,Q92945,Q9Y2L1 4
Signaling by pdgf 0.4227502377534863 0.483072089976579 0.6290445504417481 1.0 1.0 6 P46109 1
Downstream signal transduction 0.4227502377534863 0.483072089976579 0.6290445504417481 1.0 1.0 6 P46109 1
Transcriptional regulation by ventx 0.4378944143925189 0.4824037717774223 0.6295191422503601 1.0 1.0 15 Q9UPQ9,Q9UJX5,Q9HCE1 3
Activation of the pre replicative complex 0.4367272483490487 0.4810239910498246 0.6304994478183603 1.0 1.0 22 Q9UBD5,P35244,P15927,P24941,O43913,Q9NR33 6
Regulation of mrna stability by proteins that bind au rich elements 0.2601433332123283 0.4790831071060455 0.6318795069289351 1.0 1.0 65 Q14103,P04792,P55036,Q9NQT5,Q92945,Q9Y3B2,Q9Y2L1,Q14997,P49721,P20618 10
Antigen processing ubiquitination proteasome degradation 0.3046786117790288 0.4736788370397127 0.6357289469376477 1.0 1.0 95 Q9Y4B6,Q5T447,Q9GZZ9,P49720,P20618,P61081,Q15370,A0AVT1,Q8TDB6,P55786,Q7Z6J0,Q15369,P19474,Q15345,Q13309,Q15386,Q9UJX6,Q9UJX5,P55036,P28066,O95376,Q14997,P49721 23
Regulation of hsf1 mediated heat shock response 0.2806769197662282 0.4496921858052371 0.6529324065782254 1.0 1.0 55 P55735,Q0VDF9,P04792,Q9UKX7,P35244,Q7Z3B4,Q96EB6,P15927,P78406 9
Collagen formation 0.427365843575959 0.4489939731095041 0.6534360043147853 1.0 1.0 13 Q03001 1
Disorders of transmembrane transporters 0.2685487219593664 0.4404964114800911 0.6595776107722466 1.0 1.0 74 P55036,P55735,P53985,Q7Z3B4,Q14997,P49721,P20618,P78406 8
Protein protein interactions at synapses 0.4252487490205233 0.4370972596793989 0.662040814564723 1.0 1.0 14 Q92796,Q96HC4,P41440 3
Phase 0 rapid depolarisation 0.7545535980889864 0.4342554825619168 0.6641029272376153 1.0 1.0 2 Q13555 1
Pecam1 interactions 0.5307971564944896 0.4300885924693369 0.6671311978465073 1.0 1.0 3 P19174 1
Signaling by erythropoietin 0.5276282307868791 0.4205834331295598 0.6740592932479974 1.0 1.0 3 P46109 1
Butyrate response factor 1 brf1 binds and destabilizes mrna 0.4195954279140979 0.42004747933237 0.674450769186669 1.0 1.0 13 Q9NQT5,Q9Y3B2,Q15024,Q9NQT4,Q9Y2L1 5
Uptake and function of diphtheria toxin 0.4595231043421842 0.4185320776056854 0.6755581384610203 1.0 1.0 4 Q16881 1
Fatty acid metabolism 0.2508180435991269 0.4175990348636265 0.6762403025468675 1.0 1.0 58 P54646,P53007,Q4G176,Q15067,Q15165,O43772,Q709F0 7
Rrna modification in the mitochondrion 0.747685876380981 0.4165830092316945 0.6769834392438536 1.0 1.0 2 Q8WVM0 1
Constitutive signaling by aberrant pi3k in cancer 0.4040279566606261 0.4130928846002489 0.6795385623697001 1.0 1.0 6 P63000 1
Mecp2 regulates neuronal receptors and channels 0.4083782020574815 0.4106866669497013 0.6813023047929896 1.0 1.0 8 Q92769 1
Orc1 removal from chromatin 0.3035206290197445 0.4070380416887971 0.6839800482034357 1.0 1.0 51 P55036,P28066,Q99741,Q13309,Q9UBD5,O43913,P28072,P61289,Q14566,P25786,P25205,Q14997,P49720,P49721,P24941,P33992,P20618 17
Dna replication 0.2893539677616382 0.4034726873791086 0.6866005234259873 1.0 1.0 92 Q9UBD5,Q14566,Q9UJX4,P49720,P24941,P33992,P20618,Q9NR33,P18858,P49005,P41440,P35244,P12004,P56282,Q9Y2S7,Q99741,P35250,P28072,P25786,Q13309,P35251,Q9UJX6,Q9UJX5,P55036,P28066,Q9H1A4,P61289,P25205,Q14997,P15927,P49721,P49643,O43913 33
Extra nuclear estrogen signaling 0.415568382243331 0.4014956522591296 0.6880552385140848 1.0 1.0 14 P04792 1
Fcgr3a mediated il10 synthesis 0.4020683826923954 0.3966249862173931 0.6916440243536974 1.0 1.0 7 P19174,P17612 2
Cellular response to hypoxia 0.3452821371458726 0.3964297508449125 0.6917880220840571 1.0 1.0 44 P55036,Q92793,Q09472,Q9UGP4,Q15369,Q14997,P49720,Q15370,P49721,P20618 10
Synthesis of bile acids and bile salts via 7alpha hydroxycholesterol 0.4526886866177964 0.3956191689726199 0.6923859937003751 1.0 1.0 4 O14734 1
Mrna capping 0.4121103660793964 0.3929435634401628 0.6943611651797339 1.0 1.0 13 Q09161,Q92759,P18074,O43148 4
Dag and ip3 signaling 0.4069101241539505 0.3906302357090649 0.6960705730492251 1.0 1.0 10 P19174,P17612,Q13555,Q13557 4
Post translational modification synthesis of gpi anchored proteins 0.45035040579129 0.3878882467203876 0.6980987362747495 1.0 1.0 4 Q92643 1
Hdl assembly 0.7357420125410615 0.3866432787495962 0.6990203132344115 1.0 1.0 2 P17612 1
Pka mediated phosphorylation of key metabolic factors 0.7357420125410615 0.3866432787495962 0.6990203132344115 1.0 1.0 2 P17612 1
Transcriptional regulation by the ap 2 tfap2 family of transcription factors 0.4013822483292605 0.3856945717595627 0.6997228834803406 1.0 1.0 8 Q09472,P25490 2
Dap12 signaling 0.5132141506782266 0.3784490983923489 0.7050970002922266 1.0 1.0 3 P63000 1
Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1 0.3108573186404177 0.3756293391962437 0.7071924759392476 1.0 1.0 49 P55036,P28066,P53350,Q13309,Q9H1A4,P28072,P61289,P25786,Q9UJX4,O14965,Q14997,P49720,P49721,Q9UJX6,P20618,Q9UJX5 16
Cell junction organization 0.4100016631848464 0.3740008133061887 0.7084037110908277 1.0 1.0 18 Q03001,Q9BY67,Q9Y624 3
Met promotes cell motility 0.3955814164864661 0.3737602880754744 0.7085826671516868 1.0 1.0 7 P46109 1
Amino acids regulate mtorc1 0.4052852294032615 0.3734682077814887 0.7088000029434613 1.0 1.0 12 P55735,Q9NXC5 2
Cyclin a b1 b2 associated events during g2 m transition 0.4042275497026252 0.3697932262055781 0.7115365627506807 1.0 1.0 12 O95067,Q9Y570 2
Regulation of cholesterol biosynthesis by srebp srebf 0.4018946901288346 0.3664915428413562 0.713998322146447 1.0 1.0 26 Q16850,P37268 2
Downregulation of smad2 3 smad4 transcriptional activity 0.393881974149447 0.3596385102091425 0.7191174808818228 1.0 1.0 8 Q96PU5,Q13547,Q9UPN9,Q13485 4
Downstream signaling events of b cell receptor bcr 0.3251507023804157 0.3566768944339742 0.7213337048851207 1.0 1.0 46 P55036,O95999,Q14997,Q04864,P20618,O15111 6
Rna polymerase i transcription initiation 0.402063732719563 0.3535013050961953 0.7237126505202733 1.0 1.0 23 Q13547,Q9NYV6,Q92769,Q8WXI9,P18074,Q86YP4 6
Nonsense mediated decay nmd 0.2728343354928862 0.3502502810108625 0.7261508748106431 1.0 1.0 87 P62280,P36578,P25398,P08708,P15880,P46776,P46782,P61513,Q09161,Q02543,P32969,P05388,P62753,Q9UPR3,P50914,P62829,P18621,P27635,P08865,P62917,P62888,P61247,P62266,P62249,P62841,P62899 26
Metabolism of cofactors 0.42931846250704 0.3493834268803827 0.7268014737739363 1.0 1.0 5 P00374 1
Bbsome mediated cargo targeting to cilium 0.3858620459537559 0.3493434161364672 0.7268315077496037 1.0 1.0 6 P48643 1
Signaling by bmp 0.7193191997611192 0.347209752875512 0.7284337443595417 1.0 1.0 2 Q7Z3T8 1
Phase ii conjugation of compounds 0.3852994119641673 0.3447860752423873 0.7302552022576818 1.0 1.0 31 P31153,Q9NUJ1,P78417,Q8WUX2,O43708,O95340,O75223 7
Cooperation of prefoldin and tric cct in actin and tubulin folding 0.4012754652515115 0.34466102914857 0.7303492190965319 1.0 1.0 17 Q9NQP4,P48643,Q9BVA1,P17987,P49368,P40227,P61758,P04350 8
G0 and early g1 0.3869999885161663 0.3444040540769844 0.7305424404404195 1.0 1.0 7 P12004,P24941,Q99741,Q13547 4
Cellular response to heat stress 0.2408136584489601 0.3426649430032393 0.7318505390841523 1.0 1.0 66 P55735,Q0VDF9,P04792,P55072,Q99543,Q09472,Q9UKX7,P35244,Q7Z3B4,Q96EB6,Q13555,P15927,P78406 13
Signaling by ntrk2 trkb 0.426361892974921 0.3401883526394351 0.733714688933955 1.0 1.0 5 Q06124,P19174,P63000 3
Trna aminoacylation 0.3640886287207026 0.3384490236978911 0.7350248359053237 1.0 1.0 37 Q9HA77,Q9BW92,P23381,Q15181,Q12904,Q13155,Q9UGM6 7
Activation of kainate receptors upon glutamate binding 0.3822873158196154 0.3373331229070038 0.7358657930109165 1.0 1.0 6 Q92796 1
Tristetraprolin ttp zfp36 binds and destabilizes mrna 0.3960419685505395 0.3339024784311889 0.7384531495041278 1.0 1.0 14 Q9NQT5,Q9Y3B2,Q15024,Q9NQT4,Q9Y2L1 5
Signaling by tgfb family members 0.3948097575743512 0.3321094856838066 0.7398065877261071 1.0 1.0 24 Q13547,P61586,P61081,Q96PU5,Q9UPN9,Q9Y624,P62136,Q8TEW0,O75909,P62140,Q7Z3T8 11
Glucose metabolism 0.2331592663067499 0.3250352037063662 0.745154428284561 1.0 1.0 63 P55735,A6NDG6,P00558,P09972,Q9UKX7,Q7Z3B4,P60174,Q9UBX3,P17612,P04406,Q16822,Q8NFH5,P04075,P11498,P14618,P19367,P17858,P53007,P17252,P78406 20
Lagging strand synthesis 0.3951743504857594 0.3239614609931037 0.7459672117285838 1.0 1.0 20 Q9Y2S7,P35250,P35244,P15927,P35251,P18858,P49005,P41440 8
Nucleotide salvage 0.3836179372318668 0.3182573475429187 0.7502897352456737 1.0 1.0 9 P55263,P04183 2
Polymerase switching 0.3905755875403085 0.3160716732330069 0.7519481069079363 1.0 1.0 14 Q9Y2S7,P35250,P35251,P49005,P41440 5
Signaling by the b cell receptor bcr 0.3034708469230469 0.3145764676038021 0.753083248814328 1.0 1.0 48 P55036,O95999,Q14997,Q04864,P20618,O15111 6
Cytoprotection by hmox1 0.2368138252648746 0.3131904364696668 0.7541359838024535 1.0 1.0 67 O75880,P14854,Q15648,P49720,P20618,P10606,P09601,P28072,P25786,Q13309,O43819,P55036,P28066,O14867,Q92793,P61289,P19784,Q14997,P49721,P67870 20
Glutamate and glutamine metabolism 0.3768476332524602 0.3110639986778243 0.7557519692564778 1.0 1.0 7 Q96C36,O94925 2
Signaling by tgf beta receptor complex 0.3892027662307989 0.3101842212548856 0.7564208688044674 1.0 1.0 23 P61586,Q13547,P61081,Q9UPN9,Q9Y624,P62136,Q8TEW0,O75909,P62140 9
Processive synthesis on the c strand of the telomere 0.3854645805334147 0.3074770936958985 0.7584802557001509 1.0 1.0 12 Q9Y2S7,P35244,P15927,P18858,P49005 5
Notch3 intracellular domain regulates transcription 0.3724872272343617 0.3053771292738034 0.7600789385897972 1.0 1.0 6 Q09472,Q92793 2
Rho gtpases activate cit 0.3772455024316307 0.2979873749248146 0.7657127995017088 1.0 1.0 9 P62140,P63000 2
Ngf stimulated transcription 0.4215490833448313 0.2976274312589077 0.7659875357535895 1.0 1.0 4 Q09472 1
Sphingolipid de novo biosynthesis 0.3788477145256055 0.2969212033660994 0.7665266678395326 1.0 1.0 10 Q96G23 1
Regulation of tp53 activity through acetylation 0.3846827859335435 0.294637988683708 0.7682704389323858 1.0 1.0 15 Q92769,Q09472,Q8WXI9,Q86YP4 4
Mapk family signaling cascades 0.2633613389551718 0.2906258314862106 0.7713375017534565 1.0 1.0 89 P55036,P04792,P30086,Q92796,Q9HCE1,P63000,Q14997,P49721,P49354,Q9UPQ9,P20618 11
Beta oxidation of butanoyl coa to acetyl coa 0.4795561447099004 0.2878273337298772 0.7734789130539976 1.0 1.0 3 P30084 1
Hcmv early events 0.3022782770296509 0.2868640755142702 0.7742163984953083 1.0 1.0 47 P55735,O43237,Q9UER7,Q96FJ2,Q7Z3B4,P63167,P78406 7
Regulation of ifng signaling 0.4175320898325064 0.2858262274009225 0.7750112191996092 1.0 1.0 4 Q06124,O75925 2
Tbc rabgaps 0.3824296312086235 0.283320363892949 0.7769312684088125 1.0 1.0 18 P20339,Q8TC07,Q4KMP7,P49815 4
Respiratory electron transport 0.2699872296265501 0.28175481003546 0.7781315239358131 1.0 1.0 52 O75880,P14854,P51970,P19404,P49821,P10606,Q7L592,O75380,Q9BQ95,Q9BU61,O43678,P21912,P31040,Q86Y39,O95299,Q9P0J0,O43819,O75306,P47985,O00217 20
Cd28 dependent vav1 pathway 0.4064438136445575 0.2810401624443606 0.7786795955146517 1.0 1.0 5 P60953,P63000 2
Beta oxidation of pristanoyl coa 0.4056860489509998 0.2788906532444302 0.7803287417025642 1.0 1.0 5 O15254 1
Fceri mediated mapk activation 0.371018582618088 0.2788201601740247 0.7803828421735204 1.0 1.0 9 P19174,P63000,P45985 3
Intrinsic pathway for apoptosis 0.3807637524981023 0.2785118507811567 0.78061946917631 1.0 1.0 20 P98170,P63167,Q96FJ2,Q96GX9 4
Runx1 interacts with co factors whose precise effect on runx1 targets is not known 0.3806332476580626 0.2778959873061563 0.7810922042955217 1.0 1.0 18 Q09472,Q92925,Q96GM5,P67870,Q68CP9 5
Transcriptional regulation of granulopoiesis 0.3699517741873661 0.2756014379077886 0.7828542051341629 1.0 1.0 9 P24941 1
Abc family proteins mediated transport 0.2805558879869186 0.2727694623232715 0.7850304352219744 1.0 1.0 50 P55036,P55072,P08183,O75477,P41091,P20042,Q14997,P49720,P49721,P20618 10
Fceri mediated nf kb activation 0.3027571168559361 0.2685234850782445 0.7882963999620982 1.0 1.0 46 P55036,O95999,Q14997,P20618,O15111 5
Golgi to er retrograde transport 0.2323228128712638 0.2656982586656626 0.7904716045793267 1.0 1.0 71 Q9NZ32,Q9H0B6,Q99747,O43237,Q96FJ2,Q99661,O60333,Q9Y3B3,P47755,P61923,Q6NUQ1,P63167,Q14807,Q9UJW0,P24390 15
Raf independent mapk1 3 activation 0.361862970848985 0.2648111680410743 0.7911549330943533 1.0 1.0 7 Q06124,P36507,P06493 3
Glutathione conjugation 0.3731995617595012 0.2602495408183757 0.7946712923555306 1.0 1.0 15 O43708,P78417 2
Regulation of hmox1 expression and activity 0.3001370955234193 0.2596175205457302 0.7951588201885849 1.0 1.0 46 P55036,Q99436,P09601,P28066,O14867,Q13309,P28072,P61289,P25786,P19784,P67870,Q14997,P49720,P49721,P20618 15
Interleukin 1 family signaling 0.2566020881494729 0.2561838942128393 0.7978088443141877 1.0 1.0 53 P55036,P09429,Q14997,P20618,O15111 5
Nicotinate metabolism 0.3968918111177441 0.2545134952196565 0.7990988796069054 1.0 1.0 5 Q15274,Q4G0N4,Q9BQG2,P43490 4
Chrebp activates metabolic gene expression 0.3968853634927376 0.2544960130997432 0.799112383809655 1.0 1.0 5 Q13085 1
Formyl peptide receptors bind formyl peptides and many other ligands 0.6754255001493016 0.2525759454049276 0.8005959202146231 1.0 1.0 2 Q9NRV9 1
Metabolism of nitric oxide nos3 activation and regulation 0.3576704068445205 0.2525366524412219 0.8006262873748102 1.0 1.0 7 Q9Y314 1
Runx3 regulates notch signaling 0.403981971473996 0.2475739485613028 0.8044640693456824 1.0 1.0 4 Q09472 1
Regulation of gene expression in late stage branching morphogenesis pancreatic bud precursor cells 0.403981971473996 0.2475739485613028 0.8044640693456824 1.0 1.0 4 Q09472 1
Signaling by robo receptors 0.3152502301529217 0.2470768020138292 0.8048487865629557 1.0 1.0 139 P62280,P36578,P25398,O43347,P49720,P08708,P17612,P15880,P20618,P46776,P61586,P46782,P61513,P63000,Q09161,Q02543,Q15370,P32969,P05388,P62753,P50914,P62829,Q15369,O75122,P18621,P27635,P08865,P62917,P62888,P55036,P28066,Q8TEY7,Q16512,P35080,P61247,P62266,P62249,P60953,Q14997,P49721,P62841,P62899 42
Autophagy 0.2665638246906825 0.2454232315595071 0.8061287427733144 1.0 1.0 51 Q99816,P54646,O43237,Q676U5,Q96FJ2,O96008,Q8WUX9,Q9Y4P8,P63167,P67870,Q13501,P49815 12
Clec7a dectin 1 signaling 0.2665325491010045 0.2453181816158765 0.8062100749036689 1.0 1.0 51 P55036,O95999,Q14997,P20618,O15111 5
Lrr flii interacting protein 1 lrrfip1 activates type i ifn production 0.4616300730611907 0.2445143155741887 0.8068325161734242 1.0 1.0 3 Q09472 1
Rho gtpases activate formins 0.219378856462025 0.2424537122753292 0.8084286192030614 1.0 1.0 66 P55735,P61586,O43237,Q96FJ2,P63000,Q9NSV4,P35080,O75122,Q99661,Q9P258,P63167 11
Tnfr2 non canonical nf kb pathway 0.3093824655269176 0.2404758995339557 0.8099613445535607 1.0 1.0 43 P55036,Q99436,P28066,Q12933,P61081,P28072,P61289,Q8TBC4,P25786,Q14997,P49720,P49721,P20618,O15111 14
Pre notch processing in golgi 0.6688563750373286 0.2398517618710797 0.8104451777717883 1.0 1.0 2 P16615 1
Regulation of expression of slits and robos 0.2944664247064651 0.2391813449948476 0.810964967448683 1.0 1.0 124 P62280,P36578,P25398,O43347,P49720,P08708,P15880,P20618,P46776,P46782,P61513,Q09161,Q02543,Q15370,P32969,P05388,P62753,P50914,P62829,Q15369,P18621,P27635,P08865,P62917,P62888,P55036,P28066,Q8TEY7,P61247,P62266,P62249,Q14997,P49721,P62841,P62899 35
Interleukin 1 signaling 0.270391713169748 0.2376676032701134 0.8121389125890699 1.0 1.0 50 P55036,P09429,Q14997,P20618,O15111 5
Transcription of the hiv genome 0.3511948573778534 0.2360189994878643 0.8134179271445239 1.0 1.0 31 Q9Y5B0,Q92759,O43148,Q15369,O75909,Q14241,Q09161,Q15370,P18074 9
Regulation of pten stability and activity 0.3073241444055782 0.2343905388442876 0.8146818030051997 1.0 1.0 43 P98170,P55036,P49721,Q14997,P20618 5
Auf1 hnrnp d0 binds and destabilizes mrna 0.3103931970238445 0.2298055811650683 0.8182428476426262 1.0 1.0 42 P55036,P04792,P49721,Q14997,P20618 5
Ca dependent events 0.3525088056998062 0.2257816912635965 0.82137121766509 1.0 1.0 9 P17612,Q13555,Q13557 3
Fructose metabolism 0.4531700883713447 0.2253691562210598 0.821692104222993 1.0 1.0 3 Q3LXA3 1
Rna polymerase i transcription 0.3552231503000314 0.2249926052364227 0.8219850269613584 1.0 1.0 27 Q13547,Q9NYV6,Q92769,Q8WXI9,P18074,Q86YP4 6
Uch proteinases 0.2721680585131357 0.2248255455820288 0.8221149922703226 1.0 1.0 49 P55036,Q96EZ8,P25490,P85037,Q14997,P20618 6
Hdr through mmej alt nhej 0.3490074784995888 0.2219492259448723 0.824353409295701 1.0 1.0 8 P18887,P49916,P09874 3
Ksrp khsrp binds and destabilizes mrna 0.3585235608252957 0.219918056278999 0.8259349736646908 1.0 1.0 15 Q9NQT5,Q9Y2L1,Q92945,Q9Y3B2 4
G beta gamma signalling through cdc42 0.3835022241513348 0.2194833890342317 0.8262735180542755 1.0 1.0 5 P60953,P62873 2
The role of gtse1 in g2 m progression after g2 checkpoint 0.2578371052676507 0.2181865264837346 0.8272837825121304 1.0 1.0 51 O95067,P20618,P55036,Q14997 4
Rmts methylate histone arginines 0.3580761590256398 0.2176677810459224 0.827687968764091 1.0 1.0 22 Q92925,Q96GM5,P15880,Q68CP9,Q99873 5
Pka mediated phosphorylation of creb 0.3926669377637972 0.2175602693230373 0.8277717434267307 1.0 1.0 4 P17612 1
Creb1 phosphorylation through the activation of adenylate cyclase 0.3926669377637972 0.2175602693230373 0.8277717434267307 1.0 1.0 4 P17612 1
Pka activation in glucagon signalling 0.3926669377637972 0.2175602693230373 0.8277717434267307 1.0 1.0 4 P17612 1
G1 s dna damage checkpoints 0.3059249185518616 0.2175058532457393 0.8278141459545834 1.0 1.0 42 P55036,O14757,P49721,Q14997,P20618 5
Glyoxylate metabolism and glycine degradation 0.3550363329729865 0.2158579876319555 0.8290984460476849 1.0 1.0 13 P11182,P21953,P23378,P09622 4
Mitotic spindle checkpoint 0.2017244046044486 0.2151974792320976 0.8296133561719208 1.0 1.0 59 P55735,O43237,Q96FJ2,O75122,Q99661,Q9P258,P63167,Q9UJX5 8
Infectious disease 0.2003722398114877 0.2137334733161474 0.8307549065261879 1.0 1.0 362 P17612,P18754,P62873,Q13547,P46782,Q9UQB8,Q09161,P63167,P62753,Q9Y2Z0,Q9Y5B0,P50914,P62888,P55036,P55072,Q92759,O75909,Q14997,Q99873,P55735,P00558,P36578,Q96FJ2,P25398,P49720,Q8WUX9,P54709,P08708,O75446,P62487,P61513,P63000,Q9Y4I1,P12268,Q15369,P27635,Q16881,Q8WXI9,P12235,Q99816,O43237,P78362,P62280,Q7Z3B4,P49354,P20618,P18858,P18074,Q99720,Q96F07,Q02543,Q15370,Q86YP4,Q9BRG1,O43148,P18621,P62917,Q9UER7,P49721,P62841,P62899,P78406,Q9UKX7,P13639,P15880,P46776,P32969,P05388,P09601,P61160,P62829,Q92769,O94973,P19174,P20339,P45985,Q14241,P60953,P61247 79
Cdt1 association with the cdc6 orc origin complex 0.3125270569420231 0.2120659857782698 0.8320555555833016 1.0 1.0 40 P55036,P49721,Q14997,O43913,P20618 5
Metabolism of nucleotides 0.267567486191087 0.2118223835894165 0.832245605165588 1.0 1.0 49 P35754,P23921,Q96DE0,Q9Y3D8,Q16881,P00390,P04183,P36639,P15531,P55263,P12268,Q01433 12
Synthesis of pips at the plasma membrane 0.3545148170815493 0.2117981384795735 0.8322645208566979 1.0 1.0 14 Q96T51,P20339,Q96PE3 3
G2 m checkpoints 0.2404206238421716 0.2115291936570295 0.8324743543083355 1.0 1.0 89 O95067,Q8N2W9,P55036,O14757,Q9UBD5,P35250,Q92547,P33992,P35244,Q14997,P15927,P49721,P24941,O43913,P20618 15
Interleukin 12 signaling 0.3482307851131731 0.2115180028792317 0.8324830857243637 1.0 1.0 28 Q13126,P14174,P78417,O14979,P60953,P05388 6
Rna polymerase ii transcription 0.2113810719239633 0.2102916710830059 0.83344003546779 1.0 1.0 349 Q71SY5,P54646,P55212,P17931,P14854,Q9H0H0,Q15648,P24941,Q9UPQ9,P20618,P18074,P49815,O14757,Q9NVM9,Q9ULW0,Q9UL03,Q92547,P35244,P00390,Q00534,Q09161,Q15370,Q05048,Q68CP9,Q86YP4,Q9Y2X0,P42858,Q9HCE1,Q09472,P35250,Q86W42,P25490,O43148,Q15369,Q92769,Q68E01,Q96EB6,Q92993,Q01081,P30044,Q9UJX5,P55036,O15047,Q9UER7,Q16881,O75909,Q8WXI9,Q14997,P15927,P49721,P67870,Q99873 52
Tp53 regulates metabolic genes 0.3268635011834886 0.2102399279527394 0.8334804178848476 1.0 1.0 36 P54646,P14854,Q9HCE1,Q16881,P00390,P30044,Q9UPQ9 7
Pyruvate metabolism and citric acid tca cycle 0.3331959224974792 0.2101293528440633 0.8335667166131255 1.0 1.0 34 Q9H9P8,P53597,P53985,O75390,O43708 5
Gene and protein expression by jak stat signaling after interleukin 12 stimulation 0.3508445369025206 0.2099065360718148 0.8337406208285356 1.0 1.0 26 Q13126,P14174,P78417,O14979,P60953,P05388 6
Slc transporter disorders 0.3358660661232151 0.2095593529482986 0.8340116068024503 1.0 1.0 33 P55735,P78406,P53985,Q7Z3B4 4
Tcr signaling 0.2608147660786102 0.2095107669529732 0.8340495310810745 1.0 1.0 50 P55036,O95999,Q14997,P20618,O15111 5
Cellular responses to stimuli 0.2449247571803842 0.2081748793058578 0.8350924223153455 1.0 1.0 341 P55735,O43237,P14854,P62280,Q99543,Q96FJ2,Q9UKX7,Q7Z3B4,Q15024,P25398,Q15648,P15880,P24941,Q9UPQ9,P20618,P46776,P04792,Q0VDF9,Q92945,P35244,P00390,Q00534,Q9NXC5,Q02543,Q15370,P63167,P32969,P05388,P62753,P09601,P50914,Q9HCE1,P62829,Q09472,Q15369,Q96EB6,P18621,Q92993,P27635,P47755,O95070,P30044,Q9Y5K8,P62917,Q9Y3B2,Q9UJX6,Q9UJX5,Q9Y2L1,P55036,Q9NQT5,Q13164,O14867,Q16881,Q9UGP4,P45985,P61247,P20042,Q14997,P15927,P49721,P62841,P62899,P67870,P78406,Q13555,Q7Z5J4 66
Cytosolic trna aminoacylation 0.353418744986855 0.2078286221831129 0.8353627832623052 1.0 1.0 23 Q12904,Q13155,Q15181,P23381 4
Pre notch processing in the endoplasmic reticulum 0.650940579277395 0.2071488729035151 0.8358935947064778 1.0 1.0 2 Q04721 1
Notch4 intracellular domain regulates transcription 0.3761149994586185 0.2012790876226168 0.8404803535983127 1.0 1.0 5 Q09472,Q92793,Q04721 3
Cell cycle 0.1680279743876466 0.2007733820550673 0.840875777153175 1.0 1.0 313 P55735,O43237,Q9UBD5,Q96FJ2,Q9UKX7,Q7Z3B4,P04183,P42695,Q8WUX9,P24941,P33992,Q9NR33,P18858,P20618,P41440,O95067,O14757,Q9ULW0,Q92547,P35244,Q99661,Q00534,Q9P258,P00374,P63167,Q86XL3,Q8N2W9,Q9Y570,Q09472,P35250,O75122,Q92993,Q9UIS9,Q9UJX5,P55036,P62140,Q9UER7,Q14997,P15927,P49721,O43913,P67870,P78406 43
Signaling by vegf 0.3414582815368203 0.199706477207718 0.8417101477436095 1.0 1.0 29 P04792,P61586,P19174,P63000,Q96F07,P60953,P17612 7
Bile acid and bile salt metabolism 0.3395418042853584 0.1973475525206108 0.8435555694360555 1.0 1.0 8 Q96SU4,O14734 2
Synthesis of bile acids and bile salts 0.3395418042853584 0.1973475525206108 0.8435555694360555 1.0 1.0 8 Q96SU4,O14734 2
Rna polymerase iii transcription initiation from type 3 promoter 0.3361244019138721 0.1943522534254832 0.8459000732516673 1.0 1.0 7 Q9NVU0,O14802,P62875,Q9NW08,O15160,Q9BUI4 6
Rna polymerase iii chain elongation 0.3361244019138721 0.1943522534254832 0.8459000732516673 1.0 1.0 7 Q9NVU0,O14802,P62875,Q9NW08,O15160,Q9BUI4 6
Nuclear pore complex npc disassembly 0.330967155042307 0.1914476691790511 0.8481748760688717 1.0 1.0 32 O95067,P55735,P78406,Q7Z3B4 4
The citric acid tca cycle and respiratory electron transport 0.2365109735430568 0.191237544689182 0.8483394899822256 1.0 1.0 93 P00846,Q9BU61,P14854,Q9H9P8,Q7L592,O43678,O75380,P53985,P53597,O75390,O43708,Q9BQ95,P50213,Q9P0J0 14
Metabolism of amino acids and derivatives 0.3397821521916022 0.1911372543517493 0.848418060904844 1.0 1.0 195 P62280,Q13126,Q9HCC0,P36578,P09622,P19623,Q14353,P25398,P49720,P08708,Q9UBX3,P15880,P20618,Q96GX9,P46776,Q8N4J0,P46782,P61513,P00390,O43708,O95340,P21953,Q02543,Q12904,Q13155,P32969,P05388,P62753,P34896,P50914,P57772,P62829,P18621,P31937,P27635,P08865,O94925,P62917,P62888,P55036,P28066,P11182,P54136,Q02218,Q96C36,Q99714,Q16881,P23378,P62899,P62266,Q96RQ3,P62249,P61247,Q14997,P49721,P62841,Q9Y6N5 57
Mhc class ii antigen presentation 0.2141789914199025 0.1896965636764917 0.8495469137079876 1.0 1.0 56 Q9NZ32,P55735,Q9H0B6,O43237,O00139,O94973,Q96FJ2,O94855,Q99661,P47755,P63167,Q14807,Q9UJW0 13
Developmental biology 0.2494991064981836 0.1896917866659635 0.8495506572478297 1.0 1.0 271 Q71SY5,P62280,P36578,P15924,Q02487,Q13503,Q16850,A0MZ66,O43347,P25398,P49720,P08708,P17612,Q15648,P20618,P24941,P15880,P46776,P62487,P46782,P61513,P61158,P61586,P63000,Q09161,Q02543,Q15370,P32969,P05388,P62753,Q9Y2X0,Q92796,P50914,P61160,P62829,Q09472,O94887,P25490,P04632,Q15369,O75122,Q92769,P18621,P27635,P08865,P62917,P62888,P55036,P28066,Q13164,Q92793,P36507,O94973,P19174,Q8TEY7,Q16512,P35080,P61247,P62266,P62249,P60953,Q16555,Q14997,P49721,P62841,P62899,P67870 67
Cell cycle mitotic 0.1924222418454205 0.1878469274972269 0.8509966476970947 1.0 1.0 264 P55735,O43237,Q9UBD5,Q96FJ2,Q9UKX7,Q7Z3B4,P04183,P42695,Q8WUX9,P24941,P33992,Q9NR33,P18858,P20618,P41440,O95067,Q9ULW0,P35244,Q99661,Q00534,Q9P258,P00374,P63167,Q86XL3,Q9Y570,Q09472,P35250,O75122,Q9UIS9,Q9UJX5,P55036,P62140,Q14997,P15927,P49721,O43913,P67870,P78406 38
P75 ntr receptor mediated signalling 0.3464571981663583 0.1869160157020143 0.8517264817878469 1.0 1.0 19 P61586,Q13547,Q13501,P63000,Q9Y5V3,Q92769,Q9H8V3,Q92888 8
Homology directed repair 0.2575101264556073 0.1869141201763207 0.8517279680082233 1.0 1.0 49 Q8N2W9,P18887,O14757,P35250,Q92547,P35244,P15927,P24941,Q9NR33,P41440 10
Telomere c strand lagging strand synthesis 0.3440601884267094 0.1857278834768468 0.8526581608956847 1.0 1.0 23 Q9Y2S7,P35250,P35244,P15927,P35251,P18858,P49005,P41440 8
Interleukin 12 family signaling 0.3306583396822665 0.1851263919839703 0.8531299015687983 1.0 1.0 31 Q13126,P14174,P78417,O14979,P60953,P05388 6
Signaling by notch 0.1955825193368877 0.1845726837852335 0.8535642129695618 1.0 1.0 63 P55036,Q13547,Q92793,Q9HCE1,Q09472,Q92769,P49721,P16615,Q9UPQ9,P20618 10
Programmed cell death 0.2460320422713527 0.1830575925472211 0.8547528296917832 1.0 1.0 105 P55036,P98170,P55212,P09429,Q96FJ2,Q9Y5V3,Q9NR28,Q14997,Q8WUX9,P49354,P63167,Q96GX9,P41440 13
Processive synthesis on the lagging strand 0.3425491143649832 0.182686373404007 0.8550441082725542 1.0 1.0 14 Q9Y2S7,P49642,P35244,P12004,P15927,P49643,P18858,P28340,P49005 9
Rhob gtpase cycle 0.3381659204405423 0.1803665442425713 0.8568648173870212 1.0 1.0 26 P63167,Q92888,P41440 3
Intra golgi and retrograde golgi to er traffic 0.2239269693005635 0.1793542272547538 0.8576595698959997 1.0 1.0 88 Q9H0B6,Q99747,O43237,Q96FJ2,P33908,Q9UID3,Q99661,P63167,Q9UJW0,P24390,P20645,O60333,P47755,P61923,Q14964,Q14807,Q9Y3B3,Q6NUQ1,Q9NZ32 19
S phase 0.2349021831200141 0.1766186219818201 0.8598079658150308 1.0 1.0 99 Q9UBD5,Q14566,Q9UJX4,Q7Z5K2,P49720,P24941,P33992,P20618,Q9NR33,P18858,P49005,P41440,P35244,P12004,P56282,Q9Y2S7,Q99741,P35250,P28072,P25786,Q13309,P35251,Q9UJX6,Q9UJX5,P55036,P28066,Q9H1A4,P61289,P25205,Q14997,P15927,P49721,P49643,O43913 34
Translation 0.2133599773297158 0.1762665230649652 0.8600845609420273 1.0 1.0 220 P09132,P62280,Q9Y2R5,P25398,P13639,P15880,P55010,Q9NR50,P46776,Q9NP92,P82663,Q9HA77,Q9Y3D3,Q9P015,Q7Z7H8,Q02543,Q12904,Q13155,P32969,P82912,P46199,P05388,P62753,P50914,P23381,P18621,P27635,Q15181,P49458,P62917,Q7Z2W9,P20042,P62841,P62899,Q9UGM6 35
Nervous system development 0.2305239351808322 0.175480178287108 0.8607023445514479 1.0 1.0 217 P62280,P36578,A0MZ66,Q16850,P25398,O43347,P49720,P08708,P17612,P15880,P20618,P46776,P61586,P46782,P61513,P61158,P63000,Q09161,Q02543,Q15370,P32969,P05388,P62753,Q92796,P50914,P61160,P62829,O94887,Q15369,O75122,Q92769,P18621,P27635,P08865,P62917,P62888,P55036,P28066,Q13164,P36507,O94973,P19174,Q8TEY7,Q16512,P35080,P61247,P62266,P62249,P60953,Q16555,Q14997,P49721,P62841,P62899,P67870 55
Hiv life cycle 0.2167519437455344 0.1754214457831561 0.8607484905594676 1.0 1.0 84 Q99816,P55735,O43148,Q15369,O75909,Q7Z3B4,Q09161,Q8WUX9,Q15370,P78406,P18858,P18074 12
Rna polymerase iii transcription initiation from type 1 promoter 0.3366277328541396 0.174122581360986 0.8617691269164536 1.0 1.0 12 Q9Y5Q8,Q9Y5Q9,Q9UKN8,Q9NVU0,O14802,P62875,Q9NW08,Q8WUA4,Q12789,O15160,Q9BUI4 11
Formation of tubulin folding intermediates by cct tric 0.3374044814119705 0.1732210185882275 0.8624777029284121 1.0 1.0 13 P48643,Q13885,P68371,Q9BVA1,P17987,P49368,P40227,P50991,P04350 9
Neuronal system 0.2132945215769736 0.1731556731670548 0.8625290649447233 1.0 1.0 55 P21964,P54646,Q9Y2J2,Q96HC4,Q92796,O94973,P63000,P62873,Q13555,Q13557,O94925,P17612,O14795,P41440 14
Dna repair 0.2605295895909724 0.1723300676577915 0.8631780473708235 1.0 1.0 127 Q96EZ8,Q9NZJ0,Q9UBW8,P29372,Q86W56,P24941,Q9NR33,P18858,P18074,P49005,P41440,O14757,P62487,P27695,Q92547,P35244,Q8N2W9,Q9Y2S7,P18887,Q9UBZ9,Q9UNP9,Q09472,P35250,P25490,O94782,Q92993,Q8TAT6,P35251,P55072,O95551,Q14694,Q92905,Q92759,P49916,Q86WJ1,Q14258,P15927 37
Folding of actin by cct tric 0.3288239849474541 0.1715186777465588 0.8638159453368439 1.0 1.0 8 P48643 1
Metabolism of lipids 0.2659400368260186 0.1710193257853736 0.8642085696788389 1.0 1.0 199 Q96T51,Q71SY5,P54646,P37268,Q15067,Q96G23,P62136,Q96N66,Q9Y5P4,Q13503,Q16850,P38435,Q15648,P35790,Q709F0,Q96SU4,Q15392,Q15165,O43772,Q9BWD1,Q8N2W9,Q9Y2X0,Q15126,Q9UBF8,P53007,Q4G176,Q9NPH0,O15254,Q16881,O14734,Q96PE3,Q92604,P62140,P67870 34
Apoptosis 0.223262738331934 0.1700073969126041 0.8650043194402097 1.0 1.0 93 P55036,P98170,P55212,P09429,Q96FJ2,Q9Y5V3,Q9NR28,Q14997,P49354,P63167,Q96GX9 11
Adaptive immune system 0.2103347015990985 0.168912177366147 0.8658657206786138 1.0 1.0 192 P55735,Q9H0B6,O43237,Q96FJ2,Q5T447,Q9GZZ9,P49720,P17612,P20618,O15111,P09429,O00139,P63000,Q99661,Q15370,P63167,A0AVT1,Q9UJW0,Q8TDB6,P55786,Q15369,P19474,Q15345,P47755,Q13309,Q04864,Q15386,Q9UJX6,Q14807,Q9UJX5,P55036,O94973,O95376,O95999,P19174,O94855,P60953,Q14997,P49721,Q9NZ32 40
Chromatin modifying enzymes 0.2087155531981906 0.1671874780889526 0.8672225367863455 1.0 1.0 82 Q86TU7,Q96EZ8,Q8NEM7,Q9Y4A5,Q15906,O15294,P15880,O75446,Q13547,O60678,Q96GM5,Q9UBU8,Q68CP9,Q86YP4,Q9ULM3,Q09472,Q92769,Q92993,Q96EB1,Q8IUF8,O15047,Q92793,Q92925,Q8WXI9,Q99873 25
Class i mhc mediated antigen processing presentation 0.2441910420107727 0.1662102078141018 0.8679915265112976 1.0 1.0 117 P55735,Q5T447,Q9GZZ9,P20618,O15111,P09429,Q15370,A0AVT1,Q8TDB6,P55786,Q15369,P19474,Q15345,Q13309,Q9UJX6,Q9UJX5,P55036,O95376,O94855,Q14997,P49721 21
Fatty acyl coa biosynthesis 0.3357295639071286 0.165726198952602 0.8683724273711972 1.0 1.0 15 P53007 1
Transcriptional regulation by tp53 0.2562376634597396 0.1643640601806398 0.869444554574776 1.0 1.0 135 P55212,P54646,P14854,P24941,Q9UPQ9,P18074,P49815,O14757,Q9ULW0,Q92547,P35244,P00390,Q15370,Q86YP4,Q9HCE1,Q09472,P35250,Q15369,Q92769,P30044,Q9UER7,Q16881,O75909,Q8WXI9,P15927,P67870,Q99873 27
Polymerase switching on the c strand of the telomere 0.3351248396517299 0.1632477363108634 0.8703233821492251 1.0 1.0 16 Q9Y2S7,P35250,P12004,P35251,P49643,P49005,P41440 7
Rrna processing 0.1912736497517299 0.1626143474933615 0.8708220896973833 1.0 1.0 168 P62280,Q8WVM0,P36578,P22087,Q9ULX3,Q15024,P25398,Q9H0S4,P08708,P15880,P55769,P46776,Q12788,P46782,P61513,Q9Y4W2,Q02543,Q5SY16,P32969,Q9NV06,P78346,P05388,P62753,Q9Y3A2,Q9Y2R4,P50914,P62829,Q96CB9,Q9BQ52,P18621,Q8IY37,P27635,P08865,Q9NQT4,Q9Y3B2,P62917,Q9Y2L1,P62888,Q9H9L3,Q9NQT5,Q99714,P61247,P62266,P62249,P46777,P62841,P62899,O15091 48
Sumoylation of transcription cofactors 0.3350391120886869 0.1623156130861503 0.8710573202521414 1.0 1.0 17 Q8N2W9,Q9UIS9,Q09472,Q9UER7 4
Aquaporin mediated transport 0.3247190871112272 0.1622071438601191 0.871142734316144 1.0 1.0 8 P17612,Q99797 2
Mitochondrial translation 0.2135883883857684 0.1619033274955892 0.8713819824304814 1.0 1.0 54 Q9NP92,Q9P015,Q9Y3D3,Q7Z2W9,Q9Y2R5,Q7Z7H8,P82912,P46199 8
Formation of the early elongation complex 0.3331841338625705 0.1584824658108071 0.8740766363063608 1.0 1.0 17 Q9Y5B0,P62487,Q92759,Q09161,P18074 5
Transport to the golgi and subsequent modification 0.1934179134194604 0.1583141499042893 0.8742092587396828 1.0 1.0 75 P55735,Q12893,Q99747,O43237,Q96FJ2,P33908,O94855,Q9Y3B3,P47755,P61923,P63167,Q9NZ32,Q9UJW0,P24390 14
Cell cycle checkpoints 0.2208355453956259 0.1580269486649601 0.874435563555944 1.0 1.0 149 P55735,O43237,Q9UBD5,Q96FJ2,P24941,P33992,P20618,O95067,O14757,Q92547,P35244,Q99661,Q9P258,P63167,Q8N2W9,P35250,O75122,Q92993,Q9UJX5,P55036,Q14997,P15927,P49721,O43913 24
Hiv transcription elongation 0.3284785725539001 0.1576396523966471 0.8747407561145915 1.0 1.0 25 Q9Y5B0,Q92759,Q15369,Q14241,Q09161,Q15370,P18074 7
Mitotic metaphase and anaphase 0.1577372274732796 0.1565808055419341 0.875575230886952 1.0 1.0 145 O95067,P55036,P55735,O43237,Q96FJ2,Q86XL3,O75122,Q7Z3B4,Q99661,Q14997,Q8WUX9,P49721,P63167,P20618,Q9UJX5 15
Regulation of tp53 activity through phosphorylation 0.3050472480824708 0.156443528653544 0.8756834286386095 1.0 1.0 35 P54646,O14757,Q9ULW0,P35250,Q92547,P35244,P15927,P24941,P67870 9
Mitochondrial trna aminoacylation 0.3322677808942514 0.1563292241710048 0.8757735219642662 1.0 1.0 18 Q9UGM6,Q9HA77 2
Copi mediated anterograde transport 0.23542255067665 0.1563244821836313 0.8757772595726219 1.0 1.0 50 Q12893,Q99747,O43237,Q96FJ2,Q9Y3B3,P47755,P61923,P63167,Q9UJW0,P24390 10
Hiv infection 0.2049194182912031 0.1555053621006013 0.8764229270195756 1.0 1.0 140 P55036,P55735,P12235,Q99816,Q15370,P63000,O43148,O75909,Q15369,Q7Z3B4,Q14997,Q09161,Q8WUX9,P49721,P20618,P18858,P18074,P78406 18
Eukaryotic translation initiation 0.2130845028020034 0.1537711401808392 0.8777901899524729 1.0 1.0 103 P62280,P36578,P41091,P25398,P08708,P55010,Q9NR50,P15880,P46776,P46782,P61513,Q02543,P32969,Q9UI10,P05388,P62753,P50914,P62829,P18621,P27635,P08865,P62917,P62888,P61247,P62266,P62249,P20042,P62841,P62899 29
Regulation of tnfr1 signaling 0.324382326792074 0.1536103939459275 0.8779169410322258 1.0 1.0 10 O15111 1
Prc2 methylates histones and dna 0.3545309177508043 0.1528759057054937 0.8784961369998692 1.0 1.0 5 P26358,Q15022 2
Influenza infection 0.1898881994915052 0.1518338984739411 0.8793179449721722 1.0 1.0 126 P55735,P62280,P36578,Q9UKX7,Q7Z3B4,P25398,P08708,P15880,P46776,P62487,P46782,P61513,Q02543,P32969,P05388,P62753,P50914,P62829,P18621,P27635,P08865,P62917,P62888,P61247,P62266,P62249,P62841,P62899,P78406 29
Er to golgi anterograde transport 0.1822576014592378 0.1517436913541574 0.8793890954531913 1.0 1.0 71 P55735,Q12893,Q99747,O43237,Q96FJ2,O94855,Q9Y3B3,P47755,P61923,P63167,Q9NZ32,Q9UJW0,P24390 13
Signaling by interleukins 0.2090317625136096 0.1514663743675187 0.8796078341406088 1.0 1.0 117 Q8IV63,P55036,P09429,P09601,Q13164,P37275,Q13126,P14174,P45985,P78417,P46109,O14979,P60953,Q14997,P49721,P20618,O15111,P05388 18
G beta gamma signalling through pi3kgamma 0.353785064084447 0.1513338691862777 0.8797123531953257 1.0 1.0 5 P61586 1
Cyclin d associated events in g1 0.3226534855657294 0.149983183237759 0.8807778830064821 1.0 1.0 10 P24941,Q00534 2
Separation of sister chromatids 0.1592036283851638 0.1477306924588659 0.8825553083188125 1.0 1.0 111 P55036,P55735,O43237,Q96FJ2,O75122,Q99661,Q9P258,Q14997,P49721,P63167,P20618,Q9UJX5 12
Host interactions of hiv factors 0.1927927708735538 0.1477172535718407 0.8825659146380957 1.0 1.0 96 P55036,P55735,Q15370,P63000,Q15369,Q7Z3B4,Q14997,P49721,P12235,P20618,P78406 11
Dectin 1 mediated noncanonical nf kb signaling 0.2674680236662716 0.1474615761863389 0.8827677058914538 1.0 1.0 43 P55036,P20618,O15111,Q14997 4
Signaling by wnt 0.1908552293297796 0.1472577186122974 0.8829286042410098 1.0 1.0 99 P55036,P98170,P61586,O94973,Q9HCE1,Q09472,P63000,P09471,P67870,Q92993,Q14997,P49721,Q9UPQ9,P20618,P62873 15
Hdms demethylate histones 0.319269898264502 0.1464338304386145 0.8835789223151849 1.0 1.0 9 Q8IUF8,P62805,Q8NB78,Q9Y4C1,Q9Y2K7,Q9UPP1,O60341,Q7LBC6 8
Transcriptional regulation by runx2 0.1859540238061833 0.1449125571981918 0.8847799118816246 1.0 1.0 56 P55036,P20618,P17931,Q14997 4
Mitotic g2 g2 m phases 0.1792582274980968 0.1448605132588483 0.8848210033674437 1.0 1.0 92 O95067,P55036,Q9ULW0,Q9Y570,Q09472,Q14997,P49721,P62140,P24941,P63167,P20618 11
Death receptor signalling 0.3067638395624496 0.1440555810257392 0.8854565799866727 1.0 1.0 32 P63244,P98170,P61586,Q13547,Q13501,P63000,Q9Y5V3,Q92769,Q9H8V3,Q92888,O15111 11
Meiotic recombination 0.3239191118862463 0.1430739656264253 0.8862317658057848 1.0 1.0 14 P35244,P24941,P15927 3
Snrnp assembly 0.2684721048422886 0.1420545558973817 0.8870369132027396 1.0 1.0 42 P55735,P62316,Q7Z3B4,Q09161,P78406 5
Wnt mediated activation of dvl 0.410167214967137 0.1417214385288869 0.8873000403662505 1.0 1.0 3 P67870 1
Transport of the slbp dependant mature mrna 0.3073255650189193 0.1406670579909174 0.8881329701952685 1.0 1.0 31 Q09161,P55735,P78406,Q7Z3B4 4
Copi dependent golgi to er retrograde traffic 0.2356648208560921 0.1405828035966475 0.8881995340485618 1.0 1.0 48 Q9H0B6,Q99747,O95239,O00139,Q99661,P48444,O14579,Q12756,P24390,P04350,P53621,Q9BW19,O60333,P61923,O95235,P62820,Q14807,Q9H0H5,Q96Q89,Q9BVA1,Q9Y3B3,Q6NUQ1,Q9UBF2 23
Intra golgi traffic 0.3191278698700581 0.1398971737927136 0.8887412343172068 1.0 1.0 11 Q16706,Q14964,Q99747,P33908 4
Signaling by hedgehog 0.1704279844837483 0.1393004210636742 0.8892127571652311 1.0 1.0 57 P55036,Q99436,P28066,P55072,P28072,P61289,P25786,Q14997,P49720,P28070,P17612,P17252,P20618,P49721 14
Tnf signaling 0.3203823713241167 0.1379196092813082 0.8903039525467242 1.0 1.0 13 O15111 1
Tcf dependent signaling in response to wnt 0.1432096415960869 0.1379112884151021 0.8903105287967144 1.0 1.0 70 P98170,P55036,Q13547,Q92793,Q09472,Q92993,P67870,Q14997,P49721,P20618 10
Telomere maintenance 0.26471591219253 0.1369847286809977 0.8910428660608742 1.0 1.0 42 Q9Y2S7,P62487,Q9UER7,P35250,P35244,P15927,P24941,P18858,P49005,P41440 10
Sensory processing of sound 0.3215591865088151 0.1359988541554827 0.8918221868003766 1.0 1.0 18 Q14651 1
Pcp ce pathway 0.2115046932148689 0.1352952124779552 0.8923784701655857 1.0 1.0 51 P55036,P61586,P63000,Q14997,P49721,P20618 6
Metabolism of polyamines 0.2764988474311201 0.134858337518507 0.8927238803987059 1.0 1.0 39 P55036,P49721,P20618,Q14997 4
Rhoa gtpase cycle 0.236107221844363 0.1344906032319212 0.8930146411200146 1.0 1.0 47 Q9P0I2,P63167,Q92888,P41440 4
Camk iv mediated phosphorylation of creb 0.3555470263385917 0.1324517357422237 0.8946269958928668 1.0 1.0 4 Q13555 1
Aggrephagy 0.3187235307576167 0.1314173019803658 0.8954452023611035 1.0 1.0 16 P63167,Q96FJ2 2
Hdr through homologous recombination hrr 0.3090463016103086 0.1295058022150302 0.8969574341125912 1.0 1.0 27 Q9Y2S7,O14757,P35250,Q92547,P35244,P12004,Q92993,P15927,P35251,Q9NR33,P49005,P41440 12
Hcmv late events 0.2753275452875773 0.1280568196717462 0.8981040075377513 1.0 1.0 38 Q99816,P55735,Q9BRG1,Q7Z3B4,Q8WUX9,P78406 6
Microrna mirna biogenesis 0.3114333135820386 0.1278663910924983 0.8982547086930515 1.0 1.0 10 O75569,Q9HAV4 2
Attenuation phase 0.3125800620639459 0.1236702853039145 0.9015763399006658 1.0 1.0 13 P04792,Q09472 2
Hedgehog off state 0.1714229903008092 0.1234789147223247 0.9017278701197516 1.0 1.0 53 P55036,Q99436,P28066,P28072,P61289,P25786,Q14997,P49720,P28070,P17612,P17252,P20618,P49721 13
Glycolysis 0.181184350824785 0.1227572906215352 0.902299295530404 1.0 1.0 52 P55735,A6NDG6,P00558,P04406,P09972,Q9UKX7,Q8NFH5,P14618,Q7Z3B4,P19367,P60174,P04075,P17252,P17612,P78406 15
Acetylcholine regulates insulin secretion 0.397525873371425 0.1216100469932967 0.9032078562023796 1.0 1.0 3 P29966 1
Chromosome maintenance 0.209998647948296 0.1193681739717828 0.904983674474178 1.0 1.0 48 Q9Y2S7,P62487,Q9UER7,P35250,P35244,P15927,P24941,P18858,P49005,P41440 10
Dna strand elongation 0.2948199116015184 0.1188718351158136 0.9053768958381184 1.0 1.0 30 Q9Y2S7,P35250,P35244,P12004,P25205,P15927,P35251,P33992,P18858,P49005,P41440 11
Robo receptors bind akap5 0.3943527599602519 0.1168832466364531 0.9069525743926288 1.0 1.0 3 P17612 1
Rab regulation of trafficking 0.2507543510017512 0.1168275969938291 0.9069966742570575 1.0 1.0 41 Q8TC07,Q9Y2L5,P20339,P51159,P24386,Q4KMP7,P51153,Q14964,Q15286,P49815 10
Hedgehog ligand biogenesis 0.2599625055582452 0.1162016634255721 0.9074927184622869 1.0 1.0 39 P55036,Q99436,P28066,P55072,P28072,P61289,P25786,Q14997,P49720,P49721,P20618 11
Peroxisomal lipid metabolism 0.3078637181748225 0.1156395512799459 0.9079382157764716 1.0 1.0 13 O14734,P09110,Q15067,O15254 4
Degradation of beta catenin by the destruction complex 0.1377122987464184 0.1151326514400101 0.908339979872394 1.0 1.0 51 P55036,P20618,Q14997 3
Potential therapeutics for sars 0.2535551056233964 0.1148277098398264 0.908581685049257 1.0 1.0 40 O75446,Q99720,P49354,O94973,Q92769,Q8WXI9,P12268,Q86YP4 8
Creatine metabolism 0.3917043384569232 0.1130363162118446 0.9100017635376908 1.0 1.0 3 Q14353 1
Rab geranylgeranylation 0.3063744440204599 0.1125259397160371 0.910406403433594 1.0 1.0 20 P20338,Q9BZG1,P20339,P51159,P24386,P51153,P62820,Q14964,Q15286,P61026 10
Activated pkn1 stimulates transcription of ar androgen receptor regulated genes klk2 and klk3 0.3444876008365674 0.1112545135859486 0.9114145243074092 1.0 1.0 4 P16104,Q16512,P62805 3
Abc transporter disorders 0.2431848567652975 0.1109213945613618 0.9116786798836 1.0 1.0 41 P55036,Q99436,P28066,P55072,P28072,P61289,P25786,O75477,Q14997,P49720,P49721,P20618 12
Defective cftr causes cystic fibrosis 0.2431848567652975 0.1109213945613618 0.9116786798836 1.0 1.0 41 P55036,Q99436,P28066,P55072,P28072,P61289,P25786,O75477,Q14997,P49720,P49721,P20618 12
Insulin receptor recycling 0.3002261082960838 0.1105989659901951 0.9119343674770716 1.0 1.0 9 Q93050 1
Stabilization of p53 0.2501830423933716 0.1080791253580835 0.9139329266967532 1.0 1.0 39 P55036,P20618,Q14997 3
Degradation of gli1 by the proteasome 0.2272036489446193 0.1052905530659222 0.9161452588701636 1.0 1.0 42 P55036,Q99436,P28066,P28072,P61289,P25786,Q14997,P49720,P17252,P17612,P49721,P20618 12
Extension of telomeres 0.2718387027834671 0.1039203708531028 0.917232541030634 1.0 1.0 33 Q9Y2S7,P35250,P35244,P15927,P24941,P18858,P49005,P41440 8
Sensory perception 0.2866528767465141 0.1032540889432854 0.91776131250392 1.0 1.0 28 P53582,P50579,Q14651,P47755 4
Signaling by notch4 0.109266501596616 0.1030195580836508 0.9179474484351235 1.0 1.0 46 P55036,Q99436,P28066,Q92793,Q09472,P28072,P28074,P25786,P61289,Q04721,P49720,P28070,P49721,P20618,Q06330 15
Transcriptional regulation by runx3 0.1774692767988525 0.1019812270337824 0.9187715760423474 1.0 1.0 45 P55036,Q99436,P28066,Q92793,Q09472,P28072,Q13485,P25786,P61289,P49721,P49720,P20618 12
Regulation of ras by gaps 0.2405696374254325 0.1018678716765357 0.918861551953321 1.0 1.0 39 P55036,P20618,Q14997 3
Hedgehog on state 0.218454487913262 0.1016728272368622 0.9190163710740012 1.0 1.0 42 P55036,P20618,Q14997 3
Copi independent golgi to er retrograde traffic 0.284992102197373 0.1014951511628125 0.9191574064956703 1.0 1.0 28 P63167,Q96FJ2,P47755 3
Sumoylation of sumoylation proteins 0.2792006513760057 0.101313966525107 0.9193012295583772 1.0 1.0 30 P78406,P55735,Q8N2W9,Q7Z3B4 4
Parasite infection 0.2959790267257182 0.1011100345345251 0.919463112464128 1.0 1.0 22 P61160,P63000,Q96F07,Q9Y4I1,P60953,Q9UQB8 6
Degradation of axin 0.2504620872926705 0.1010174959849719 0.9195365714337788 1.0 1.0 37 P55036,P20618,Q14997 3
Nuclear envelope breakdown 0.2059627742242299 0.1009661849690443 0.919577303450543 1.0 1.0 43 O95067,P55735,P78406,Q7Z3B4 4
Regulation of runx2 expression and activity 0.191375802914806 0.1009372569906508 0.9196002673239504 1.0 1.0 44 P55036,P20618,Q14997 3
Leishmania infection 0.2207552378218432 0.099381407522275 0.9208354443243524 1.0 1.0 41 P09601,P61160,P19174,P63000,Q96F07,Q9Y4I1,P60953,Q9UQB8,P17612,P62873 10
Downregulation of erbb2 erbb3 signaling 0.572708271125709 0.0993600968742932 0.9208523640176468 1.0 1.0 2 P40818 1
Runx1 regulates transcription of genes involved in differentiation of hscs 0.2101092852366989 0.0991137546055536 0.921047951266663 1.0 1.0 42 P55036,P20618,Q14997 3
Sumoylation of ubiquitinylation proteins 0.2732894001779994 0.0988429446314853 0.9212629705383156 1.0 1.0 31 P78406,P55735,Q8N2W9,Q7Z3B4 4
Cyclin a cdk2 associated events at s phase entry 0.1513761332335211 0.0984395578666039 0.9215832645653732 1.0 1.0 44 P55036,Q99436,P28066,Q13309,P28072,P61289,P25786,P49721,P49720,P24941,P20618 11
Degradation of dvl 0.2336189578211975 0.0983180052466814 0.921679781328964 1.0 1.0 39 P55036,P20618,Q14997 3
Trna processing in the nucleus 0.2252221673258209 0.0979385384370645 0.9219810978259612 1.0 1.0 40 Q9Y3I0,P55735,Q99575,Q9UKX7,Q9BQ52,Q7Z3B4,P78406,Q52LJ0 8
Rac1 gtpase cycle 0.1863902011894035 0.0976931490022407 0.9221759558387316 1.0 1.0 43 P63000,Q96F07,Q9NSV4,Q16513,P60953,Q9UQB8,Q9H8V3,P63167 8
Tp53 regulates transcription of dna repair genes 0.2541853407334909 0.0968195247319992 0.9228697182845368 1.0 1.0 35 Q9Y5B0,O14757,Q92759,Q15369,O75909,Q14241,Q15370,P18074 8
Asymmetric localization of pcp proteins 0.2269459832736183 0.0955480947117686 0.9238794909130096 1.0 1.0 39 P55036,P20618,Q14997 3
Interleukin 6 signaling 0.3352255751419162 0.0950041798668666 0.924311506886602 1.0 1.0 4 Q06124,P42224,P40763 3
Interleukin 6 family signaling 0.3352255751419162 0.0950041798668666 0.924311506886602 1.0 1.0 4 Q06124,P42224,P40763 3
Scf skp2 mediated degradation of p27 p21 0.1809760612253097 0.094691245451213 0.9245600718498628 1.0 1.0 42 P55036,Q99436,P28066,Q13309,P28072,P61289,P25786,P49721,P49720,P24941,P20618 11
Cross presentation of soluble exogenous antigens endosomes 0.2292979944843901 0.0934544483547467 0.9255425362057929 1.0 1.0 38 P55036,P20618,Q14997 3
Formation of rna pol ii elongation complex 0.2484811203986377 0.0933636806146994 0.9256146431214312 1.0 1.0 35 Q9Y5B0,Q92759,Q15369,O75909,Q14241,Q09161,Q15370,P18074 8
Regulation of pten gene transcription 0.2902683580851997 0.0929626441701451 0.9259332382988752 1.0 1.0 21 Q12873,Q13547,Q9Y2Q5,O94776,Q15022,Q92769,Q8WXI9,Q9UKL0,Q86YP4 9
Uptake and actions of bacterial toxins 0.2894641076154104 0.091631856801548 0.9269905398507214 1.0 1.0 10 P13639,Q16881,P45985 3
Rna polymerase ii transcribes snrna genes 0.2554020809246345 0.0914595665927323 0.9271274327212528 1.0 1.0 33 Q9NVM9,Q9H0H0,O75909,Q68E01,Q09161 5
Hsf1 dependent transactivation 0.2914957286126536 0.0907542424645511 0.9276878691662316 1.0 1.0 17 P04792,Q09472,Q13555 3
Interactions of vpr with host cellular proteins 0.2433535933424132 0.0906717341719096 0.92775343095442 1.0 1.0 35 P12235,P55735,P78406,Q7Z3B4 4
Sumoylation of dna replication proteins 0.2187624720270784 0.0901000659143351 0.9282076968420768 1.0 1.0 38 P78406,P55735,Q8N2W9,Q7Z3B4 4
Transport of mature mrnas derived from intronless transcripts 0.2249276655792678 0.0891083066986527 0.928995835868128 1.0 1.0 37 Q09161,P55735,P78406,Q7Z3B4 4
Regulation of runx3 expression and activity 0.2144604581771863 0.0890435177601916 0.9290473252842388 1.0 1.0 38 P55036,Q99436,P28066,Q09472,P28072,P61289,P25786,P49721,P49720,P20618 10
Negative regulation of notch4 signaling 0.1260146844201051 0.0887283939981316 0.9292977663793872 1.0 1.0 40 P55036,P20618 2
Neurotransmitter receptors and postsynaptic signal transmission 0.191951901628307 0.0856437756977845 0.931749598303605 1.0 1.0 38 P54646,Q92796,O94973,P63000,Q13555,P17612 6
Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand 0.2500352621867406 0.0855580187256428 0.9318177722368132 1.0 1.0 32 P63167,Q96FJ2,P47755 3
Sumoylation of chromatin organization proteins 0.185702551742548 0.0851508723178082 0.9321414468707484 1.0 1.0 38 P55735,Q9UKX7,Q92769,Q7Z3B4,P78406 5
Protein folding 0.1661425306742689 0.0843103175697416 0.9328097093768126 1.0 1.0 38 P61962,Q9NQP4,P48643,Q15813,P62873,Q99426,P17987,P19784,Q9Y2T2,P67870,P61758,P04350 12
Rhoc gtpase cycle 0.2388926278633906 0.0831158223798376 0.9337594449379673 1.0 1.0 33 Q12802,P61586,Q13017,Q9NSV4,Q16513,P63167,Q92888,P41440 8
Generation of second messenger molecules 0.3270871068480429 0.0818521792442758 0.9347642622063568 1.0 1.0 4 P19174 1
Rho gtpases activate iqgaps 0.283796298865528 0.0817892343460591 0.9348143171385066 1.0 1.0 12 P63000 1
Selective autophagy 0.2322928470486734 0.0807145312791399 0.9356689802339846 1.0 1.0 33 P54646,O43237,Q96FJ2,O96008,P63167,P67870,Q13501 7
Interleukin 20 family signaling 0.3661887694145579 0.0804773554294787 0.9358576055589088 1.0 1.0 3 Q06124,P40763 2
Regulation of ifna signaling 0.3661887694145564 0.080477355429477 0.93585760555891 1.0 1.0 3 P18031,Q06124 2
Glutathione synthesis and recycling 0.2737304467304411 0.0774550464200536 0.9382615515510608 1.0 1.0 6 O75223 1
Positive epigenetic regulation of rrna expression 0.2347444805619862 0.0764411335227953 0.9390681455002784 1.0 1.0 31 Q92769,Q09472,Q8WXI9,Q86YP4 4
Cytosolic sensors of pathogen associated dna 0.2640012167042546 0.0746557622598706 0.9404886060010352 1.0 1.0 24 P19474,Q09472,O15111,Q9H2U1 4
Activation of nmda receptors and postsynaptic events 0.2581473814891185 0.0730052666348218 0.941801926528144 1.0 1.0 25 P54619,P54646,Q92796,P63000,Q13555,Q13557,P17612 7
Runx2 regulates genes involved in cell migration 0.5431472081218309 0.0728797398106309 0.9419018163519456 1.0 1.0 2 P31751 1
Fcgamma receptor fcgr dependent phagocytosis 0.2307988738256281 0.0727404825899427 0.9420126334106628 1.0 1.0 30 P61158,P61160,P19174,P63000,Q96F07,Q8IV08,Q9Y4I1,P60953,Q9UQB8 9
Interleukin 3 interleukin 5 and gm csf signaling 0.2741521382816358 0.0727276655612492 0.9420228329053442 1.0 1.0 9 P46109,P17612,O15357,P17252 4
Notch hlh transcription pathway 0.2725817278024007 0.0721340278147784 0.9424952464698196 1.0 1.0 8 Q92769,Q13547 2
Tp53 regulates transcription of cell cycle genes 0.2709286375466136 0.0685081120121351 0.9453811627974787 1.0 1.0 16 Q9UIV1,Q09472,O14965,P24941,Q99873 5
Regulation of glucokinase by glucokinase regulatory protein 0.2315032715881468 0.0681962894535004 0.945629380684056 1.0 1.0 28 P55735,P78406,Q7Z3B4 3
Export of viral ribonucleoproteins from nucleus 0.2065106391044741 0.0677836273547092 0.9459578772612668 1.0 1.0 30 P55735,P78406,Q7Z3B4 3
Hiv elongation arrest and recovery 0.2585932398047763 0.0673749978448497 0.9462831727808948 1.0 1.0 22 Q9Y5B0,P62487,O75909,Q15369,Q14241,Q15370 6
Formation of incision complex in gg ner 0.2683628284926433 0.0671671429674759 0.9464486421469572 1.0 1.0 17 P18074,P15927 2
Rna polymerase i promoter escape 0.2686941462070222 0.0665471834612329 0.9469421939651036 1.0 1.0 16 Q9NYV6,P18074 2
Rho gtpases activate wasps and waves 0.265806099154118 0.0650919683363528 0.9481007752114392 1.0 1.0 17 P61160,P63000,Q96F07,P60953,Q9UQB8 5
Formation of tc ner pre incision complex 0.2217175484728356 0.0611019173398873 0.951278042189607 1.0 1.0 26 P62487,Q09472,Q9UBW8,Q92905,Q92759,P18074 6
Ion channel transport 0.2213975700958188 0.0587872666985856 0.9531215506226078 1.0 1.0 25 Q96PU5,Q93050,P51790,Q9Y5K8,Q13557,P16615,P54709,Q13555 8
Mrna decay by 5 to 3 exoribonuclease 0.2582522456222268 0.0552659012755692 0.9559266274706008 1.0 1.0 11 Q96F86,Q9NPI6,Q6P2E9,Q9Y333,Q9UK45,Q9Y4Z0 6
Cooperation of pdcl phlp1 and tric cct in g protein beta folding 0.2558407301585082 0.0547780878347251 0.956315257561061 1.0 1.0 14 P17987,P67870,P48643,P62873 4
Collagen biosynthesis and modifying enzymes 0.2562874251497024 0.0535981418316695 0.9572553369893836 1.0 1.0 11 P50454,P07237,Q8NBJ5,Q32P28,O15460,O00469,O60568,O75718,P23284,Q02809 10
Abortive elongation of hiv 1 transcript in the absence of tat 0.2541803644457376 0.0535912077578115 0.9572608616396852 1.0 1.0 14 Q9Y5B0,P62487,Q09161 3
Dna damage recognition in gg ner 0.2387671981197227 0.0519526849461508 0.9585663944066148 1.0 1.0 19 Q9UBW8,P25490 2
Initiation of nuclear envelope ne reformation 0.241862297563646 0.0516116724159468 0.9588381184942 1.0 1.0 18 O95067 1
Cargo concentration in the er 0.252764903445109 0.0511777556541596 0.9591838770285424 1.0 1.0 12 Q9HCU5,O95486,O94855,P53634 4
Insulin processing 0.2526389356728999 0.0504405625818858 0.9597713132423292 1.0 1.0 10 Q96HE7,Q8IYI6,P51159,Q9Y4I1,Q9UPT5 5
Interleukin 23 signaling 0.5067184234099803 0.0494918176095336 0.9605273578122248 1.0 1.0 2 P07237 1
Citric acid cycle tca cycle 0.229844918122211 0.0486242483481195 0.961218745430857 1.0 1.0 19 P53597,P09622,P31040,O75390,P50213 5
Activation of anterior hox genes in hindbrain development during early embryogenesis 0.2313312329596584 0.0472986080631148 0.9622752374475656 1.0 1.0 18 Q09472,P25490,Q92793 3
Signaling by fgfr in disease 0.206798573285194 0.04513676480732 0.9639982971939368 1.0 1.0 20 P19174,Q9UBW7,Q09161 3
Foxo mediated transcription of oxidative stress metabolic and neuronal genes 0.28189554392443 0.0439636386288145 0.9649333879985597 1.0 1.0 5 Q92769,Q13547 2
Association of tric cct with target proteins during biosynthesis 0.1455145514551429 0.036606160189702 0.9707990317029048 1.0 1.0 18 P61962,O00567,P48643,P51784,Q9BUR4,P50990,Q9H0D6,Q99832,P17987,P49368,P04637,P40763,P40227,P50991,P78371,Q15477,Q9Y2T2 17
Peptide hormone metabolism 0.2134095282243341 0.0346005921806785 0.9723982292920784 1.0 1.0 14 P51159,Q9UPT5,Q9Y4I1,P62873 4
Epha mediated growth cone collapse 0.2285372419982017 0.0330268149418078 0.9736532040704724 1.0 1.0 8 P61586,O75116,P60660,P07947,P35579,Q15375,Q13464 7
Condensation of prophase chromosomes 0.2188588968566743 0.0330052506120276 0.9736704005411344 1.0 1.0 12 Q86XI2,P53350,P42695,P06493 4
Nucleotide biosynthesis 0.2126139800843315 0.0326344457542219 0.973966100712061 1.0 1.0 13 P12268,P20839,P31939,P30520 4
Alpha oxidation of phytanate 0.2877203465790169 0.032589667289104 0.9740018097638684 1.0 1.0 4 P51648,Q9UJ83,O14975 3
Trafficking of ampa receptors 0.2043940834020375 0.0287465845633181 0.9770667025946218 1.0 1.0 12 Q13555,O94973,Q13557 3
Rna polymerase iii transcription 0.1713213818937488 0.026028784590375 0.9792343794417906 1.0 1.0 13 Q9Y5Q8,Q8WUA4,Q9UKN8 3
Rna polymerase i transcription termination 0.189861026058827 0.0259266754932447 0.9793158232283736 1.0 1.0 12 P18074 1
Dna damage reversal 0.2759620702737833 0.0221630188885698 0.982317916991323 1.0 1.0 4 Q8N3C0 1
Inhibition of dna recombination at telomere 0.1689929772113177 0.0193121645004276 0.9845920798709152 1.0 1.0 10 Q9UER7 1
Base excision repair ap site formation 0.2341491423292717 0.0123619594533968 0.990136834623106 1.0 1.0 5 P29372,P13051 2
Tnfr1 induced proapoptotic signaling 0.2441198891140405 0.0022185092135102 0.99822988720256 1.0 1.0 4 Q6GQQ9 1