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Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
Synthesis of pg 0.973595394866325 2.957044399926999 0.0031060338869524 0.986877652647356 0.1244850597705321 3 Q8IV08 1
Er quality control compartment erqc 0.9651979626247704 2.922893171626948 0.0034679547720166 0.9920870689674728 0.1244850597705321 3 Q9UBV2 1
Transport and synthesis of paps 0.9063180827886664 2.68261456092936 0.0073049127591371 0.99996331314086 0.1271967934184754 2 O43252 1
Irak1 recruits ikk complex 0.8854652972300046 2.594992523884974 0.0094592976521936 0.999998221106642 0.1401787407394231 2 O15111 1
Ikba variant leads to eda id 0.8854652972300046 2.594992523884974 0.0094592976521936 0.999998221106642 0.1401787407394231 2 O15111 1
Maturation of sars cov 1 nucleoprotein 0.8350451291627778 2.3792878015064174 0.0173461269113066 0.9999999999740584 0.1902610613185053 2 P49840 1
Rora activates gene expression 0.8334371108343707 2.3677261425256866 0.0178977783656417 0.9999999999881348 0.192592381369864 3 Q96RS0,Q15648 2
Synthesis of ip3 and ip4 in the cytosol 0.8163709928415834 2.2980078044281056 0.0215613449409506 0.9999999999999348 0.2100346398793303 2 Q01968 1
Diseases of immune system 0.81254916177695 2.2763002552015945 0.0228280448600033 0.9999999999999892 0.2152944178586661 3 O15111 1
Bmal1 clock npas2 activates circadian gene expression 0.8131423232637758 2.274377364943343 0.0229433071848843 0.9999999999999908 0.2152944178586661 4 Q86X55,Q96RS0,Q15648 3
Ras processing 0.8119275374720109 2.264843647730608 0.0235222758848756 0.999999999999996 0.2155692783396827 5 P36404,O60725 2
Transcriptional regulation by e2f6 0.8121361578481133 2.2501527203465956 0.0244392523943077 0.9999999999999988 0.2159748801539697 10 P31350,P38398,Q9UBK9,Q06609 4
Ticam1 rip1 mediated ikk complex recruitment 0.787938070381458 2.1673727354858427 0.0302064444590361 1.0 0.219727203867168 3 O15111 1
Ikk complex recruitment mediated by rip1 0.787938070381458 2.1673727354858427 0.0302064444590361 1.0 0.219727203867168 3 O15111 1
Synthesis of pa 0.7854775186732328 2.1344934984895287 0.0328024052891953 1.0 0.219727203867168 8 Q9NPH0,Q9NUQ2,Q8N2A8 3
Signaling by fgfr4 in disease 0.772798008092128 2.105445901485964 0.0352525117619773 1.0 0.219727203867168 2 P19174 1
Role of lat2 ntal lab on calcium mobilization 0.7727980080921057 2.1054459014858646 0.0352525117619859 1.0 0.219727203867168 2 O00459 1
Interleukin receptor shc signaling 0.7730386052303851 2.1008007812303684 0.0356584578532181 1.0 0.219727203867168 3 O00459,P23458 2
Pd 1 signaling 0.7699968876439462 2.092929156790721 0.0363554790329287 1.0 0.219727203867168 2 P41240 1
Netrin mediated repulsion signals 0.7699968876439462 2.092929156790721 0.0363554790329287 1.0 0.219727203867168 2 P12931 1
Activated ntrk2 signals through frs2 and frs3 0.7699968876439449 2.092929156790716 0.0363554790329292 1.0 0.219727203867168 2 P62993 1
Frs mediated fgfr1 signaling 0.7699968876439449 2.092929156790716 0.0363554790329292 1.0 0.219727203867168 2 P62993 1
Pi 3k cascade fgfr1 0.7699968876439449 2.092929156790716 0.0363554790329292 1.0 0.219727203867168 2 P62993 1
Frs mediated fgfr2 signaling 0.7699968876439449 2.092929156790716 0.0363554790329292 1.0 0.219727203867168 2 P62993 1
Frs mediated fgfr3 signaling 0.7699968876439449 2.092929156790716 0.0363554790329292 1.0 0.219727203867168 2 P62993 1
Pi 3k cascade fgfr3 0.7699968876439449 2.092929156790716 0.0363554790329292 1.0 0.219727203867168 2 P62993 1
Stat5 activation downstream of flt3 itd mutants 0.7699968876439449 2.092929156790716 0.0363554790329292 1.0 0.219727203867168 2 P62993 1
Frs mediated fgfr4 signaling 0.7699968876439449 2.092929156790716 0.0363554790329292 1.0 0.219727203867168 2 P62993 1
Pi 3k cascade fgfr4 0.7699968876439449 2.092929156790716 0.0363554790329292 1.0 0.219727203867168 2 P62993 1
Signaling by flt3 itd and tkd mutants 0.7699968876439449 2.092929156790716 0.0363554790329292 1.0 0.219727203867168 2 P62993 1
Pi 3k cascade fgfr2 0.7699968876439449 2.092929156790716 0.0363554790329292 1.0 0.219727203867168 2 P62993 1
Stat5 activation 0.7699968876439449 2.092929156790716 0.0363554790329292 1.0 0.219727203867168 2 P62993 1
Downstream signaling of activated fgfr4 0.7702366127023652 2.0882289518421495 0.0367771868727437 1.0 0.219727203867168 3 P62993,P19174 2
Tie2 signaling 0.7702366127023653 2.0882289518421495 0.0367771868727437 1.0 0.219727203867168 3 O00459,P62993 2
Downstream signaling of activated fgfr3 0.7702366127023652 2.0882289518421495 0.0367771868727437 1.0 0.219727203867168 3 P62993,P19174 2
Downstream signaling of activated fgfr1 0.7702366127023652 2.0882289518421495 0.0367771868727437 1.0 0.219727203867168 3 P62993,P19174 2
Downstream signaling of activated fgfr2 0.7702366127023652 2.0882289518421495 0.0367771868727437 1.0 0.219727203867168 3 P62993,P19174 2
Gab1 signalosome 0.7704764870756777 2.083965354369451 0.0371633187955691 1.0 0.219727203867168 4 P41240,P62993,P12931 3
Hs gag biosynthesis 0.7625272331154485 2.059471032206351 0.0394491372495127 1.0 0.2270770586304595 2 Q93063 1
Synthesis of pips at the late endosome membrane 0.7603485838779955 2.049690560134051 0.0403946367818957 1.0 0.2311055647310226 2 Q99570 1
Cytochrome p450 arranged by substrate type 0.7610987971283745 2.0471158879623164 0.0406467073647527 1.0 0.2311055647310226 3 P16435 1
Smac xiap regulated apoptotic response 0.755680049797699 2.028699373615415 0.0424889197458266 1.0 0.2376990570519541 2 Q9NR28 1
Purinergic signaling in leishmaniasis infection 0.7500353288958826 1.9913779550377544 0.0464393509736944 1.0 0.254685101993529 4 P09601 1
Class i mhc mediated antigen processing presentation 0.3931327035011458 1.961442670457679 0.0498274064831729 1.0 0.2679906456797681 115 P19474,P28074,P52888,O94822,Q9BSL1,P25787,P49427,Q9UJX5,Q9UJX3,P28072,Q9NZ08,P49721,P55786,Q9UJX4,Q9UIQ6,P28070,O00231,O15111,Q9UJX6,Q05086,Q13042 21
Metabolism of folate and pterines 0.7457990723155499 1.952094333020857 0.0509270059329045 1.0 0.2706407018520873 8 P00374,Q9H2D1 2
Endosomal vacuolar pathway 0.7374728921075216 1.934052864815877 0.053106628398571 1.0 0.2730919740835378 4 Q9UIQ6 1
Ephrin signaling 0.7404843399804938 1.9320706807074508 0.0533507825484296 1.0 0.2731998596791137 7 Q14155 1
Egr2 and sox10 mediated initiation of schwann cell myelination 0.7390409673492367 1.9305206006654576 0.0535423652051667 1.0 0.2731998596791137 6 Q9NR77 1
Calnexin calreticulin cycle 0.739682423099314 1.923687112418103 0.0543938144035571 1.0 0.2742598134335497 8 Q9UBV2 1
The nlrp3 inflammasome 0.7359241056520951 1.9213393325627264 0.054688941511944 1.0 0.2742598134335497 5 P09601 1
Inflammasomes 0.7359241056520951 1.9213393325627264 0.054688941511944 1.0 0.2742598134335497 5 P09601 1
Dap12 signaling 0.7346183982000505 1.9209831476357568 0.0547338321138024 1.0 0.2742598134335497 4 O00459,P19174 2
Platelet sensitization by ldl 0.7337080821503003 1.9111448906268496 0.0559859636399313 1.0 0.2775389585424355 5 Q16539,P30154 2
Ptk6 regulates proteins involved in rna processing 0.727895392278953 1.8962886722074417 0.0579218833449206 1.0 0.2831059070156999 3 Q07666,O75525 2
Erythropoietin activates ras 0.7254901960784327 1.8918899320773783 0.0585056474876422 1.0 0.2849593250009985 2 P62993 1
Cd163 mediating an anti inflammatory response 0.7245564892623728 1.8876299249346231 0.0590756497978621 1.0 0.2856030198417485 2 Q16539 1
Signaling by erythropoietin 0.7257160647571596 1.886312262302704 0.0592528878207216 1.0 0.2856030198417485 3 P62993,P19174 2
Signal regulatory protein family interactions 0.7262535035814323 1.8825909407910977 0.0597558250297431 1.0 0.2870340147118354 4 P62993,Q06124,P12931 3
Irs mediated signalling 0.723967889830672 1.8662227593172511 0.0620102061351035 1.0 0.2938102624020383 5 O00459,Q99570,P62993 3
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane 0.7229417799787702 1.8614796074370092 0.0626764778028299 1.0 0.2959604528113291 5 P36404 1
Other interleukin signaling 0.719546459986625 1.8580196948631855 0.063166217535068 1.0 0.2970034279745867 3 P23458 1
S phase 0.3862550717903394 1.85691129976917 0.0633237746650769 1.0 0.2970034279745867 105 P28074,P41440,Q9BRT9,Q5TKA1,P51530,P25787,Q96DE5,Q9UJX5,Q9UJX3,P28072,Q9NRF9,P49721,Q9Y619,Q99436,Q9UJX4,Q9BRX5,P28070,O00231,Q9UJX6,Q13042 20
Conversion from apc c cdc20 to apc c cdh1 in late anaphase 0.7218045934838445 1.8246106467853125 0.0680598056193106 1.0 0.3139314875089397 12 Q9UJX4,Q9UJX5,Q9UJX6,Q9UJX3,Q13042 5
Signaling by ntrk2 trkb 0.7148094535522475 1.8182034441863852 0.0690330437992243 1.0 0.3173697360142559 6 P62993,Q06124,P19174,P12931 4
Regulation of pten localization 0.7077497665732969 1.8106656675133337 0.0701926204273257 1.0 0.3200869864390221 2 P46934 1
Antigen processing ubiquitination proteasome degradation 0.4580325288764062 1.8034344697069729 0.0713200082575686 1.0 0.3236116335595869 91 P19474,P28074,P52888,O94822,Q9BSL1,P25787,P49427,Q9UJX5,Q9UJX3,P28072,P49721,P55786,Q9UJX4,Q9UIQ6,P28070,O00231,Q9UJX6,Q05086,Q13042 19
Aberrant regulation of mitotic exit in cancer due to rb1 defects 0.7122865098466765 1.7761621071235418 0.0757062019090566 1.0 0.3326774109126684 13 Q9UJX4,Q9UJX5,Q9UJX6,Q9UJX3,Q13042 5
Ptk6 regulates rho gtpases ras gtpase and map kinases 0.7011524932885931 1.7602938710961655 0.0783579928145052 1.0 0.3432474339327228 5 P46108 1
Dap12 interactions 0.7009940060659194 1.7536716786381934 0.0794867810815023 1.0 0.3471005832179709 6 O00459,P10321,P19174 3
G1 s specific transcription 0.7047434735284144 1.7429645749615683 0.0813398029541851 1.0 0.3529792695176946 12 Q9Y619,P00374,Q5TKA1 3
Class i peroxisomal membrane protein import 0.7009473607965556 1.7325218697602394 0.0831806866741087 1.0 0.3565048537985353 10 Q8TB36,Q9NR77,Q5T8D3 3
Signaling by type 1 insulin like growth factor 1 receptor igf1r 0.6927478106334501 1.714992009762552 0.0863466918823923 1.0 0.366463940653273 6 O00459,Q99570,P62993 3
Cdc6 association with the orc origin complex 0.6860397538153173 1.6896147842307792 0.0911016756480307 1.0 0.3782032150287996 5 Q9Y619 1
G2 m dna replication checkpoint 0.6842105263157757 1.687648640654421 0.0914786962160976 1.0 0.3782032150287996 4 P14635,O95067,Q99640 3
Signaling by interleukins 0.3729869279868327 1.687173837282373 0.0915699305308679 1.0 0.3782032150287996 106 P08670,P25787,O00231,P09601,P28074,O15111,Q9H3S7,O00459,P28072,P78417,Q07820,Q13126,P51809,P30154,P46108,P49721,P28070 17
Disassembly of the destruction complex and recruitment of axin to the membrane 0.6812595360263751 1.6609137613608642 0.0967307680307927 1.0 0.384988456762555 6 P49841,P30154 2
Beta catenin phosphorylation cascade 0.6812595360263751 1.6609137613608642 0.0967307680307927 1.0 0.384988456762555 6 P49841,P30154 2
Signaling by ctnnb1 phospho site mutants 0.6812595360263751 1.6609137613608642 0.0967307680307927 1.0 0.384988456762555 6 P49841,P30154 2
Nrage signals death through jnk 0.6790500498575298 1.644165821213075 0.1001419548438162 1.0 0.3901347312769213 7 Q14155,Q9H8V3 2
Flt3 signaling in disease 0.6762384459568783 1.6435734307078842 0.1002643458701635 1.0 0.3901347312769213 5 P62993,Q92614 2
Signaling by erbb2 in cancer 0.6697055981637992 1.612802364681524 0.1067874522227416 1.0 0.4064342102357354 5 Q96RT1,P19174 2
Signaling by erbb2 ecd mutants 0.6697055981637992 1.612802364681524 0.1067874522227416 1.0 0.4064342102357354 5 Q96RT1,P19174 2
Insulin receptor signalling cascade 0.6706988452086111 1.6110165728500232 0.1071761103048936 1.0 0.4068019663616261 6 O00459,P62993,Q99570 3
Role of phospholipids in phagocytosis 0.6664257159858125 1.5973294715497826 0.1101922846772978 1.0 0.4126286359018167 5 Q8IV08 1
Signaling by flt3 fusion proteins 0.661813449882273 1.5825818513266257 0.1135168027399919 1.0 0.4216770832448235 4 Q92614 1
Rho gtpase cycle 0.3439959409473076 1.5715215752427647 0.1160615469347003 1.0 0.4260693121814161 166 Q13505,Q96N67,P49257,P06753,P41440,P27105,P30519,O60879,Q9UQB8,Q92888,Q7L576,Q5T8D3,Q96AC1,Q9H8V3,Q9BXB4,O15173,Q13190,Q14155,Q9UNZ2,P50402,P84095,O00459,P61201,O75976,Q96RT1,O94887,Q14739,P08670,A4D1P6,Q6IAA8,Q01968,Q8NBN3,Q86XL3,Q14185 34
Cell death signalling via nrage nrif and nade 0.6650865931272008 1.5659184170541574 0.1173677176601757 1.0 0.4284062350617316 9 Q14155,Q9H8V3 2
Heme signaling 0.662207051591858 1.5641231557338688 0.1177886489796433 1.0 0.4284062350617316 7 Q96EB6,Q96RS0,P09601,Q15648 4
Rip mediated nfkb activation via zbp1 0.6581310426134432 1.5581311116815126 0.1192021709362918 1.0 0.4310608784156947 5 O15111 1
Zbp1 dai mediated induction of type i ifns 0.6581310426134432 1.5581311116815126 0.1192021709362918 1.0 0.4310608784156947 5 O15111 1
Cation coupled chloride cotransporters 0.6526610644257742 1.554952513706842 0.1199573791787818 1.0 0.4310608784156947 2 P55011 1
Signaling by fgfr4 0.658251719489302 1.5519962772179643 0.1206631143779799 1.0 0.4310608784156947 6 P62993,P19174,P12931 3
Signaling by fgfr1 0.658251719489302 1.5519962772179643 0.1206631143779799 1.0 0.4310608784156947 6 P62993,P19174,P12931 3
Signaling by fgfr3 0.658251719489302 1.5519962772179643 0.1206631143779799 1.0 0.4310608784156947 6 P62993,P19174,P12931 3
Apc c cdc20 mediated degradation of cyclin b 0.6657059134948367 1.5467544841268828 0.1219224595088181 1.0 0.4310608784156947 14 Q9UJX4,Q9UJX5,Q9UJX6,Q9UJX3,Q13042 5
Mastl facilitates mitotic progression 0.6504643016647783 1.5290661424977154 0.1262480477283709 1.0 0.4429811851023192 4 P14635,P30154 2
Downregulation of erbb4 signaling 0.646759912922042 1.5192309611356456 0.1287043706093937 1.0 0.446375621784618 3 P46934 1
Beta oxidation of pristanoyl coa 0.648018084611605 1.5175094808283192 0.1291381016361816 1.0 0.446375621784618 4 O15254 1
Transcriptional regulation by ventx 0.6593493538760811 1.5095173163930653 0.1311666334658094 1.0 0.4511484454762286 16 Q9UJX4,Q9UJX5,Q9UJX6,Q9UJX3,Q13042 5
Synthesis of dna 0.4355339173671853 1.5036864036093427 0.1326621317006646 1.0 0.4546286689474132 90 P28074,P41440,Q9BRT9,P51530,P25787,Q96DE5,Q9UJX5,Q9UJX3,P28072,Q9NRF9,P49721,Q9Y619,Q99436,Q9UJX4,Q9BRX5,P28070,O00231,Q9UJX6,Q13042 19
Glycerophospholipid biosynthesis 0.6539559008427737 1.4928514743812584 0.1354760697201196 1.0 0.4570401794577495 30 Q8IV08,P35790,Q8NCC3,Q9NPH0,Q9NUQ2,Q8N2A8 6
Constitutive signaling by overexpressed erbb2 0.6427782655730307 1.492730796018022 0.1355076686992096 1.0 0.4570401794577495 4 Q96RT1 1
Phosphorylation of the apc c 0.6536911389466666 1.4877079070370232 0.1368279414375364 1.0 0.4570401794577495 14 Q9UJX4,Q9UJX5,Q9UJX6,Q9UJX3,Q13042 5
Post chaperonin tubulin folding pathway 0.6475445824615474 1.4876109346099051 0.1368535280701921 1.0 0.4570401794577495 8 Q9BUF5,P36404,Q9BTW9 3
Downstream signal transduction 0.64840408505271 1.4856571780387693 0.137369822744221 1.0 0.4570401794577495 9 Q06124,P12931,P19174,O00459,P62993,P46108 6
Signaling by pdgf 0.64840408505271 1.4856571780387693 0.137369822744221 1.0 0.4570401794577495 9 Q06124,P12931,P19174,O00459,P62993,P46108 6
Rho gtpases activate nadph oxidases 0.6412193510078973 1.47793497339031 0.1394251841783116 1.0 0.4602352643611092 5 Q99570,Q13526 2
P130cas linkage to mapk signaling for integrins 0.6370221808683579 1.47331837856753 0.1406652073069343 1.0 0.4621382872135837 3 P46108 1
Resolution of d loop structures 0.6466202212932591 1.4660922874967677 0.1426231465706808 1.0 0.4652266173914917 11 P38398,Q14191,Q06609 3
Resolution of d loop structures through synthesis dependent strand annealing sdsa 0.6466202212932591 1.4660922874967677 0.1426231465706808 1.0 0.4652266173914917 11 P38398,Q14191,Q06609 3
Gpvi mediated activation cascade 0.6391795460178002 1.4611750869286204 0.1439673981227036 1.0 0.4663874083370377 6 P84095,O00459 2
Dna replication 0.3909467675224026 1.4578186525105188 0.1448905355596881 1.0 0.4672048982283461 96 P28074,P41440,Q9BRT9,P51530,P25787,Q96DE5,Q9UJX5,Q9UJX3,P28072,Q9NRF9,P49721,Q9Y619,Q99436,Q9UJX4,Q9BRX5,P28070,O00231,Q9UJX6,Q13042 19
Interleukin 2 family signaling 0.6356321244395033 1.4513679246952849 0.1466774363700709 1.0 0.4707872554458727 5 O00459,P23458 2
Cristae formation 0.6483790542344384 1.4486485177176918 0.1474357644983388 1.0 0.4711281518664952 19 Q13505,O75964,P56385,O75431,Q6UXV4 5
Adaptive immune system 0.3298708182000153 1.444176039906629 0.1486894628854413 1.0 0.4721307146842717 190 P19474,P62942,P28074,P52888,O94822,Q9BSL1,P30154,P25787,P49427,Q9UJX5,O00459,Q9UJX3,P28072,O75935,Q9NZ08,P49721,Q99436,P55786,Q9UJX4,Q9UIQ6,P28070,Q9UJW0,O00231,Q13561,Q5KU26,O15111,Q9UJX6,Q05086,Q13042 29
Heme degradation 0.6321849079902365 1.4425426192520785 0.1491493574917965 1.0 0.4721307146842717 4 P30519,P09601 2
Biosynthesis of specialized proresolving mediators spms 0.6302677659478727 1.441411307232593 0.1494685177141161 1.0 0.4721307146842717 3 P34913 1
Small interfering rna sirna biogenesis 0.6300900997752341 1.4249850399619637 0.1541615255729844 1.0 0.4828813430066558 5 Q9UPY3,O75569 2
Cytochrome c mediated apoptotic response 0.6257935743279018 1.4202513069209812 0.1555345315599006 1.0 0.4836151840690659 3 Q9NR28 1
Gamma carboxylation hypusine formation and arylsulfatase activation 0.6353120849157696 1.411022950263531 0.1582378469965002 1.0 0.4887479398361969 11 Q9HA64,O60725,P38435 3
Mitochondrial protein import 0.6279974886288414 1.3784341602003636 0.1680692826101846 1.0 0.5041526269299332 35 Q13505,O60830,Q99595,Q9NS69,P12235,Q8N4H5 6
Synthesis of pips at the golgi membrane 0.6232226970346431 1.377505343882401 0.1683560637540666 1.0 0.5041526269299332 7 Q99570,Q9UBF8,Q10713,Q01968 4
Negative regulation of fgfr4 signaling 0.6189733956615231 1.3719837423193155 0.1700684989607208 1.0 0.5041526269299332 5 P62993,P12931 2
Negative regulation of fgfr3 signaling 0.6189733956615231 1.3719837423193155 0.1700684989607208 1.0 0.5041526269299332 5 P62993,P12931 2
Negative regulation of fgfr1 signaling 0.6189733956615231 1.3719837423193155 0.1700684989607208 1.0 0.5041526269299332 5 P62993,P12931 2
Negative regulation of fgfr2 signaling 0.6189733956615231 1.3719837423193155 0.1700684989607208 1.0 0.5041526269299332 5 P62993,P12931 2
Spry regulation of fgf signaling 0.6189733956615231 1.3719837423193155 0.1700684989607208 1.0 0.5041526269299332 5 P62993,P12931 2
Peptide ligand binding receptors 0.6220443468024597 1.3718422980239615 0.1701125364785176 1.0 0.5041526269299332 7 P42892 1
Class a 1 rhodopsin like receptors 0.6220443468024597 1.3718422980239615 0.1701125364785176 1.0 0.5041526269299332 7 P42892 1
Dcc mediated attractive signaling 0.6155746535338479 1.3636388255946517 0.1726812661829284 1.0 0.5054552119675476 4 Q14185 1
Transport of vitamins nucleosides and related molecules 0.6216457934250745 1.362911884629791 0.1729102826912734 1.0 0.5054552119675476 8 P36404,P12235,Q8TB61 3
Striated muscle contraction 0.6185185638574484 1.362369774508888 0.1730812175940561 1.0 0.5054552119675476 6 P08670,P28289 2
Diseases of dna repair 0.6264687934044886 1.3533629349671308 0.1759397124685198 1.0 0.5105054595457279 14 P38398,Q14191,Q06609 3
Nephrin family interactions 0.6194099204754836 1.3521212257305877 0.1763365382150523 1.0 0.5105054595457279 8 P12814,Q01082,Q9Y5K6,O00459,Q13813,O43707 6
Organelle biogenesis and maintenance 0.3945798308711386 1.3458324619115078 0.1783565538588327 1.0 0.5112153899698643 94 Q13505,Q96RS0,Q9H6D7,A6NIH7,P54646,Q10713,Q6UXV4,Q86X55,Q96FJ2,Q14203,Q9Y478,Q9UPT5,O75935,O95684,O75964,P56385,Q13561,O00411,O75431,Q15648 20
Tp53 regulates transcription of several additional cell death genes whose specific roles in p53 dependent apoptosis remain uncertain 0.6069094304388489 1.339511260763896 0.1804042910316705 1.0 0.5132754683795144 2 Q92696 1
Tp53 regulates transcription of caspase activators and caspases 0.6069094304388485 1.339511260763893 0.1804042910316714 1.0 0.5132754683795144 2 Q13315 1
Transport of small molecules 0.329356556706435 1.337094130163048 0.1811919129700554 1.0 0.5132754683795144 166 P28074,Q70HW3,P30519,P08183,P98194,P21281,Q8WTV0,P25787,P36404,Q8TB61,P28072,Q9UBV2,P49721,Q8TDW0,Q99436,Q9BUN8,Q9NWR8,Q9NRK6,Q8TAD4,Q9GZP9,P10644,P12235,P28070,P40855,O00231,P09601,P21796 27
Apc cdc20 mediated degradation of nek2a 0.6237110125166843 1.3356779401460537 0.1816545627502517 1.0 0.5132754683795144 15 Q96DE5,Q13257,Q9UJX4,Q9UJX5,Q9UJX6,Q9UJX3,O60566,Q13042 8
Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components 0.6237110125166843 1.3356779401460537 0.1816545627502517 1.0 0.5132754683795144 15 Q96DE5,Q13257,Q9UJX4,Q9UJX5,Q9UJX6,Q9UJX3,O60566,Q13042 8
Diseases of mitotic cell cycle 0.624347180340893 1.332093322605571 0.1828295242852147 1.0 0.5155496504641783 17 Q9UJX4,Q00534,Q9UJX5,Q9UJX6,Q9UJX3,Q13042 6
Platelet calcium homeostasis 0.6049267451234679 1.3048964269150758 0.1919281180871213 1.0 0.5359358614276527 5 P23634,Q14571 2
Dna damage reversal 0.6048931734866602 1.3047359742675448 0.1919827673025116 1.0 0.5359358614276527 5 Q9H1I8,Q8N9N2 2
Sphingolipid de novo biosynthesis 0.6109010910578397 1.2918139836051177 0.1964215715154944 1.0 0.5450502970539517 11 Q96G23,Q06136,O15269 3
Signaling by pdgfra transmembrane juxtamembrane and kinase domain mutants 0.5992540311437728 1.2859376673639704 0.1984648165105491 1.0 0.5482156526931219 4 O00459 1
Diseases of signal transduction by growth factor receptors and second messengers 0.3342037200409639 1.2835668772717566 0.199293545467545 1.0 0.5486480411784392 148 P62942,P28074,Q92734,P06753,P49841,Q92614,P30154,P25787,Q14203,O43252,P84095,P20618,O00459,P28072,Q9UQ13,Q13363,Q9UBV2,P49721,Q99436,Q6UN15,Q99956,O95684,Q96RT1,Q9GZP9,P19174,P10644,Q14997,P49840,P21359,P28070,O00231,P49815,O15111,Q9NRY5 34
Metabolism of lipids 0.320123042168691 1.2744785801239071 0.2024938591274525 1.0 0.5563588673856832 189 Q96G23,Q96RS0,O43772,Q9HCL2,Q8IV08,Q9BWD1,P35790,Q8NCC3,P07602,P34913,P54646,Q9NPH0,O15254,Q5T8D3,Q8N2A8,O43681,Q15165,Q06136,Q9UBM7,O00459,Q9NRA0,Q15125,Q9BY49,Q8NCE2,Q16850,Q15392,Q9NUQ2,O15269,Q96T51,Q14739,O95772,P38435 32
Cytosolic sulfonation of small molecules 0.592833837026322 1.2553459780423704 0.2093531910992685 1.0 0.5662698935947205 4 O43252 1
E2f enabled inhibition of pre replication complex formation 0.5920852420777147 1.2355921222328872 0.2166102144251818 1.0 0.5703932489494863 6 Q9Y619,Q9UBD5 2
Synthesis of pips at the plasma membrane 0.594106498413957 1.2227327480653916 0.2214306537669199 1.0 0.5806063691946801 9 Q96T51,O00459,Q8NCE2 3
Rac2 gtpase cycle 0.5984101272653003 1.219715558272712 0.2225727215721171 1.0 0.5806063691946801 36 Q14739,Q13505,P49257,Q96RT1,O00459,Q86XL3,Q7L576 7
Suppression of apoptosis 0.5809959179317646 1.207723685901137 0.2271535641014919 1.0 0.5881503992441974 3 P49840 1
Protein localization 0.4901501499192616 1.2045001652274632 0.2283963182385031 1.0 0.5891779098263609 74 O43681,Q13505,O60830,Q9NR77,Q9BY49,Q99595,P12235,P09601,Q9NS69,Q5JRX3,P34913,Q8TB36,P21796,O15254,Q5T8D3,Q8N4H5 16
Regulation of signaling by cbl 0.579894585270037 1.185208887695676 0.2359348667735399 1.0 0.6041493923079799 5 O00459,P62993,P46108 3
Intra golgi and retrograde golgi to er traffic 0.3593576763891931 1.1670743136474726 0.2431803600004323 1.0 0.6170314052469985 97 Q9P2W9,O95235,P61923,P20645,P24390,O95721,Q96FJ2,Q13190,Q14203,Q5VIR6,O15260,Q8TBA6,O00461,O43752,O75935,Q14746,P11717,P83436,Q8WTW3,Q9UJW0,P54920,Q13561,Q9Y678,Q6NUQ1,O60333,O60476 26
Traf6 mediated nf kb activation 0.5771986493921563 1.1641667684799932 0.2443564346099438 1.0 0.6188882062030032 6 O15111 1
G alpha 12 13 signalling events 0.579902395572719 1.1538309459311926 0.2485694843045491 1.0 0.6275352068354735 9 Q14155,Q9H8V3 2
Interleukin 7 signaling 0.5686059243971948 1.139925844332429 0.2543171968379347 1.0 0.6360212840130037 4 O00459 1
Signaling by wnt in cancer 0.5696001981815282 1.111479632468869 0.2663619522404139 1.0 0.6544238293234577 8 Q13363,P49841,P30154 3
Metabolism of porphyrins 0.5693532855623074 1.1102886503088072 0.2668746622816855 1.0 0.6544238293234577 8 P50336,P09601 2
Phase i functionalization of compounds 0.57682950344882 1.1076330209520215 0.2680203365220044 1.0 0.6544238293234577 14 Q5VT66,P16435,O43169 3
Reduction of cytosolic ca levels 0.5617043675906785 1.107095370911766 0.2682526967291416 1.0 0.6544238293234577 4 P23634 1
Carnitine metabolism 0.5623309910571754 1.1013270050220143 0.2707543619786934 1.0 0.6570011185821713 5 O43772 1
Mapk1 erk2 activation 0.560277595440311 1.1003131059702362 0.2711957237507167 1.0 0.6570011185821713 4 Q06124,P23458 2
N glycan trimming in the er and calnexin calreticulin cycle 0.5725975375725963 1.0815720008821197 0.2794427513723003 1.0 0.6673789354391767 15 Q9UBV2,Q9GZP9 2
Notch4 activation and transmission of signal to the nucleus 0.5521319638966784 1.0804144108557523 0.2799576814194671 1.0 0.6673789354391767 2 Q92542 1
Cholesterol biosynthesis 0.5724159236165819 1.0715697302043368 0.2839133352919609 1.0 0.6673789354391767 17 Q15392,Q9UBM7,Q9BWD1,Q15125 4
Constitutive signaling by egfrviii 0.5534647246885633 1.0679558024383462 0.2855404490464819 1.0 0.6673789354391767 4 P19174 1
Constitutive signaling by ligand responsive egfr cancer variants 0.5534647246885633 1.0679558024383462 0.2855404490464819 1.0 0.6673789354391767 4 P19174 1
Signaling by egfr in cancer 0.5534647246885633 1.0679558024383462 0.2855404490464819 1.0 0.6673789354391767 4 P19174 1
Activation of ppargc1a pgc 1alpha by phosphorylation 0.5501020667440915 1.0520048323370332 0.2927973325654571 1.0 0.6763958279663048 4 P54646 1
Ret signaling 0.5536455361823287 1.0428514263463209 0.2970171091843001 1.0 0.6832279095312204 7 O00459,P62993,P19174,P12931 4
Cdc42 gtpase cycle 0.5687275151930298 1.0419267912076524 0.2974456218682459 1.0 0.6832279095312204 33 Q14739,Q14155,Q96N67,A4D1P6,Q6IAA8,O00459,Q9UQB8,Q9H8V3 8
Signaling by cytosolic fgfr1 fusion mutants 0.554796727644976 1.0401881696873363 0.2982524867065557 1.0 0.6833317664181449 8 O95684 1
E2f mediated regulation of dna replication 0.5588219256492182 1.0308645026984855 0.3026043648884031 1.0 0.6910293119500748 12 Q9Y619,P30154 2
Deubiquitination 0.3801436988372541 0.9913003334757938 0.3215389502155186 1.0 0.7172145974897695 91 Q99436,P25787,O00231,P28074,Q8IXI2,Q8NB78,Q6GQQ9,P28072,Q9NWV8,Q96K76,Q9UPU5,Q70CQ2,Q99496,P38398,P21796,P54725,P49721,P28070 18
P75 ntr receptor mediated signalling 0.5537746715038007 0.9884763350683264 0.3229194187222828 1.0 0.7172145974897695 15 O14920,Q14155,Q9H8V3 3
Signaling by egfr 0.5507086826685781 0.9849529407689356 0.3246471869949816 1.0 0.7172145974897695 13 Q14155,P12931,P41240,P19174,Q9UBC2,P62993 6
Grb2 sos provides linkage to mapk signaling for integrins 0.5313419617990446 0.9728211302186766 0.3306422089517489 1.0 0.7264741278703253 3 P12931 1
Rhoa gtpase cycle 0.5304164048018049 0.9710767373236356 0.3315100669791344 1.0 0.727233894963676 52 Q14739,O15173,Q14155,P49257,Q96RT1,P41440,P30519,O00459,Q8NBN3,Q92888,Q5T8D3,Q9H8V3 12
Hdr through single strand annealing ssa 0.553375462899527 0.9615614267696394 0.3362699555187098 1.0 0.7353595730573985 21 P38398,Q14191,Q92889,Q06609 4
Pink1 prkn mediated mitophagy 0.5379261640192095 0.959340053970001 0.3373874635139509 1.0 0.7366469226879836 8 Q8N4H5,Q9NS69 2
Synthesis of pips at the early endosome membrane 0.5279422085112909 0.9568661469349896 0.3386348200580942 1.0 0.7382133088277391 3 Q99570 1
Budding and maturation of hiv virion 0.5393055968294407 0.9502094953889676 0.3420058148080414 1.0 0.7409239502762078 10 Q8WUX9 1
Constitutive signaling by aberrant pi3k in cancer 0.529967954705134 0.9299454184469528 0.3523993454123584 1.0 0.7563825703534903 7 P84095,O00459,P62993,P12931 4
Regulation of runx1 expression and activity 0.5213727435812001 0.916517201725496 0.3593956894381995 1.0 0.7630224406963172 4 Q00534,P12931 2
Sema4d induced cell migration and growth cone collapse 0.5268120980317366 0.914990737110182 0.3601964929369556 1.0 0.7630224406963172 7 Q7Z406,P35580,P60660,P35579 4
Downstream signaling events of b cell receptor bcr 0.5356988105164197 0.9087656030688188 0.3634738668047474 1.0 0.765989555913787 43 Q99436,O00231,P28074,P62942,O15111,P28072,P28070,P49721,P25787 9
Nef and signal transduction 0.5144724556489383 0.9039285246428695 0.3660333026997384 1.0 0.7702181127805674 2 Q13177 1
Interferon gamma signaling 0.532680460541519 0.8972570442606976 0.3695817722464318 1.0 0.7741765544951572 13 P19474,P23458,Q12899,O15344,P10321,O75925 6
Interleukin 3 interleukin 5 and gm csf signaling 0.5261022544021269 0.8948152591039982 0.3708858519698454 1.0 0.7746864368238315 9 Q06124,P23458,O00459,P62993,P46108 5
Formation of incision complex in gg ner 0.5333818189671422 0.8884206595860594 0.3743145164266437 1.0 0.7747698683243903 15 O75925,Q92889,P54725,P32780 4
Regulation of ifng signaling 0.5150100359202283 0.8774153504918851 0.3802610784079323 1.0 0.7835853287311386 5 O75925,P23458 2
Phospholipid metabolism 0.5241679492517884 0.8656606256559282 0.3866762984862957 1.0 0.7956278933403397 46 Q9HCL2,Q8IV08,P35790,Q8NCC3,O00459,Q9NPH0,Q9NUQ2,Q8N2A8 8
Activation of ampk downstream of nmdars 0.5116720010308919 0.8527633754574268 0.3937905379079707 1.0 0.8090711199200636 6 P54646 1
Lipophagy 0.5072121229397663 0.8410535039221873 0.4003179613065271 1.0 0.8140772556204267 5 P54646 1
Tnfr1 induced nfkappab signaling pathway 0.5082136162557538 0.8366141960784469 0.4028094633609007 1.0 0.816223590282223 6 O15111,Q6GQQ9 2
Mitochondrial biogenesis 0.5298773873756685 0.835862033037522 0.4032325236339347 1.0 0.816223590282223 35 Q13505,O75964,Q96RS0,Q9Y478,P56385,O00411,O75431,P54646,Q15648,Q6UXV4,Q86X55 11
Mapk family signaling cascades 0.3644894298181871 0.8276072561373938 0.4078929575727952 1.0 0.8187246252145586 91 P49354,Q99436,P36404,Q96P70,P25787,O00231,O60725,P28074,O00459,P28072,Q9UQ13,P30154,P49721,P28070 14
Interleukin 15 signaling 0.4988462650864522 0.8216092064853313 0.411299347841747 1.0 0.8220085961887427 3 P23458 1
Gpcr ligand binding 0.5084399393648823 0.8112849643459948 0.4172020425717444 1.0 0.8281977207689589 9 P42892 1
Binding and uptake of ligands by scavenger receptors 0.5065726951563587 0.8109944739640623 0.417368844206611 1.0 0.8281977207689589 8 Q8WTV0 1
Dscam interactions 0.4961071317346641 0.7991962613127191 0.4241766194770298 1.0 0.837317478992215 4 Q16539,P63000,Q13153 3
Abc transporter disorders 0.5161465508446386 0.7958573775802545 0.4261149373161976 1.0 0.8383871577421799 43 Q99436,O00231,P28074,Q9GZP9,P28072,P28070,Q9UBV2,P49721,P25787 9
Defective cftr causes cystic fibrosis 0.5161465508446386 0.7958573775802545 0.4261149373161976 1.0 0.8383871577421799 43 Q99436,O00231,P28074,Q9GZP9,P28072,P28070,Q9UBV2,P49721,P25787 9
Endosomal sorting complex required for transport escrt 0.5074374534920192 0.7906885824926864 0.4291257403358257 1.0 0.8411062934642181 11 Q8WUX9 1
Activation of rac1 0.4962616822429785 0.7903757142295184 0.4293083809426123 1.0 0.8411062934642181 5 P63000,Q13177,Q13153,O94813 4
Egfr downregulation 0.4984944682366974 0.7733487814911469 0.4393159932467645 1.0 0.8486992464156038 8 Q14155 1
Interleukin 20 family signaling 0.4895768837944404 0.7692745829192232 0.4417303226519262 1.0 0.8486992464156038 4 P23458 1
Interleukin 6 family signaling 0.4895768837944404 0.7692745829192232 0.4417303226519262 1.0 0.8486992464156038 4 P23458 1
Interleukin 6 signaling 0.4895768837944404 0.7692745829192232 0.4417303226519262 1.0 0.8486992464156038 4 P23458 1
Hdr through homologous recombination hrr 0.5179711668177382 0.7662268838597764 0.4435413147096623 1.0 0.8486992464156038 30 P41440,Q14191,Q06609,P38398,P51530 5
Fgfr1 mutant receptor activation 0.4988940717711698 0.7584341029372215 0.4481911485203871 1.0 0.8540769765922014 10 O95684 1
Homologous dna pairing and strand exchange 0.5108764922489504 0.7533075845718306 0.4512651021469276 1.0 0.8540927816449323 20 P38398,Q14191,Q06609 3
Signaling by scf kit 0.4936780985224945 0.7510464157611858 0.4526247221993629 1.0 0.8546955161406837 8 O00459,P62993,P12931 3
Cohesin loading onto chromatin 0.4971701034684089 0.7503990447051371 0.4530144061249788 1.0 0.8546955161406837 10 Q8N3U4,Q8WVM7,Q7Z5K2,Q6KC79,Q9NTI5,Q9Y6X3,Q9UQE7 7
Pecam1 interactions 0.4833615589522292 0.7409829980488118 0.4587037491638868 1.0 0.8588640308198235 4 P12931,P19174 2
Netrin 1 signaling 0.4960737350481151 0.7373871363254336 0.4608869559181827 1.0 0.860610629482612 11 Q16539,Q14185,P19174,P12931 4
Activation of nima kinases nek9 nek6 nek7 0.4837025223721058 0.732909259303277 0.4636137753375768 1.0 0.8638236030449135 5 O95067 1
Lysosome vesicle biogenesis 0.4993009832362788 0.7308859285349761 0.4648488316582644 1.0 0.8638236030449135 14 P20645 1
Signaling by kit in disease 0.4825846677482921 0.7185168245306391 0.4724386778666836 1.0 0.8720520614664852 6 O00459,P12931 2
Map3k8 tpl2 dependent mapk1 3 activation 0.4797816197790163 0.7151335339848895 0.4745265345237586 1.0 0.8720520614664852 5 O15111 1
Hedgehog ligand biogenesis 0.5032681293626197 0.7118975910842095 0.4765281939670864 1.0 0.8745767775970374 41 O00231,P28074,Q9GZP9,P28072,P28070,Q9UBV2,P49721,P25787 8
Cytokine signaling in immune system 0.2881287219140699 0.7096339149669401 0.4779311825398591 1.0 0.8759975490500311 172 P19474,P28074,P78417,P46108,P30154,P25787,O00459,P28072,Q13126,P49721,Q99436,Q9H3S7,Q07820,P51809,P28070,Q13526,P08670,O00231,P09601,O15111,O75925 21
Potential therapeutics for sars 0.5026463002871245 0.7001385758822771 0.4838407669150744 1.0 0.8805171832635054 39 Q02790,P62942 2
Diseases of mismatch repair mmr 0.4719800747197988 0.6996747157323816 0.4841304701560511 1.0 0.8805171832635054 3 P43246,P20585 2
Activated notch1 transmits signal to the nucleus 0.4696545284780732 0.6995800011385137 0.4841896355921358 1.0 0.8805171832635054 2 Q92542 1
Processive synthesis on the c strand of the telomere 0.4918267795685046 0.6957721449047771 0.4865715362109211 1.0 0.8836951107455191 14 Q14191 1
Cd28 dependent vav1 pathway 0.4755375506388343 0.6866315746125566 0.4923149260629382 1.0 0.8894872788659831 6 Q13177,Q16512,P63000,Q13153,P62993 5
Sumoylation of transcription cofactors 0.4826534558733253 0.6753251902453723 0.4994691830812483 1.0 0.8954447516501659 11 Q99496,O75925 2
Rhob gtpase cycle 0.4986348615573067 0.670839937837638 0.5023225021208806 1.0 0.8968811299642924 27 O00459,P41440,Q9H8V3 3
Switching of origins to a post replicative state 0.4577509583174213 0.670443498418742 0.5025751133660039 1.0 0.8968811299642924 63 Q99436,Q96DE5,Q9Y619,Q9UBD5,P28074,Q9UJX4,O00231,Q9UJX5,Q9UJX3,Q9UJX6,P28072,P28070,Q13042,P49721,P25787 15
Ripk1 mediated regulated necrosis 0.48295950542124 0.6690091798654344 0.5034896221335798 1.0 0.8968811299642924 12 P41440 1
Signaling by the b cell receptor bcr 0.4873207331605894 0.6507340633349935 0.5152181704230736 1.0 0.9070135403755878 46 Q99436,O00231,P28074,P62942,O15111,P28072,P28070,P49721,P25787 9
Intra golgi traffic 0.4873503715463063 0.6448812087885983 0.5190041700385475 1.0 0.910545099324555 19 P83436,P54920,Q8TBA6,Q8WTW3,O00461,O60476,O95721,Q13190 8
Rac1 gtpase cycle 0.4849116236059524 0.6369922237077574 0.5241299088620544 1.0 0.9172886023370976 46 Q14739,Q14155,Q96N67,Q96RT1,Q6IAA8,O00459,Q9UQB8,O94887,Q14185,Q7L576,Q96AC1,Q9H8V3 12
Abc family proteins mediated transport 0.4728603710548716 0.6369384817010116 0.5241649156211987 1.0 0.9172886023370976 54 Q99436,Q9BUN8,O00231,P28074,Q9NRK6,Q9GZP9,P08183,P28072,P28070,Q9UBV2,P49721,P25787 12
Tak1 activates nfkb by phosphorylation and activation of ikks complex 0.4579352329925649 0.6178146249706018 0.5366975417732944 1.0 0.930155261711248 5 O15111 1
Diseases associated with n glycosylation of proteins 0.4600651941732607 0.6177376762861778 0.5367482720915306 1.0 0.930155261711248 6 Q9H3H5,O75340 2
Free fatty acids regulate insulin secretion 0.4509803921568658 0.617569469832349 0.5368591747421705 1.0 0.930155261711248 2 O95573 1
Signaling by insulin receptor 0.476807576880396 0.6129655588086316 0.5398991130028774 1.0 0.9331010724727148 16 Q9Y487,P38606,Q06124,O00459,P21281,Q9UI12,P61421,Q93050,Q99570,P62993 10
Separation of sister chromatids 0.2900829351136428 0.6025037607196185 0.5468388606257064 1.0 0.9404278183353196 106 Q9BS16,Q99436,P25787,O00231,P28074,Q9UJX4,Q9UJX5,Q9UJX6,Q9UJX3,P28072,Q8NBT2,P30154,Q13042,P49721,P28070 15
Met promotes cell motility 0.4592104111265819 0.59538423334999 0.5515866621777998 1.0 0.9456989236246296 8 P62993,P46108,Q96N67,P12931 4
Transport of connexons to the plasma membrane 0.4476961394769593 0.5931084394907541 0.5531085827844278 1.0 0.9456989236246296 3 Q9BUF5,P68371 2
Gap junction assembly 0.4476961394769593 0.5931084394907541 0.5531085827844278 1.0 0.9456989236246296 3 Q9BUF5,P68371 2
Signaling by fgfr1 in disease 0.4641783680834359 0.591810846886473 0.5539772589215346 1.0 0.9456989236246296 11 O95684 1
Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1 0.4645194692720666 0.5861369634422401 0.5577834784047737 1.0 0.9474686142689692 54 Q9UJX4,P28074,O00231,Q9UJX5,Q9UJX3,Q9UJX6,P28072,P28070,Q13042,P49721,P25787 11
Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways 0.4643310944329142 0.5846089897993333 0.5588106615688637 1.0 0.9474686142689692 12 O15111,P09601,Q9Y2Z0 3
Carboxyterminal post translational modifications of tubulin 0.4478355652444745 0.5837077366719723 0.5594169611892792 1.0 0.9474686142689692 4 Q14166,Q9BUF5,P68371 3
Ion transport by p type atpases 0.4622100929269084 0.5830653787023525 0.5598492891339981 1.0 0.9474686142689692 11 P16615,P23634,P98194,P05026,Q9HD20 5
Rac3 gtpase cycle 0.4818300513086538 0.5811798528289185 0.5611192447343014 1.0 0.9474686142689692 35 Q14739,O15173,P49257,Q96RT1,Q6IAA8,Q01968,O00459,Q9UQB8,Q7L576,Q96AC1 10
Fceri mediated mapk activation 0.4538653366583625 0.5811558859169108 0.5611353961033019 1.0 0.9474686142689692 7 Q13177,P19174,Q13153,Q16512,P63000,P62993 6
Telomere c strand lagging strand synthesis 0.4770975178613948 0.5781738158485208 0.5631467748787258 1.0 0.949713628820902 23 Q14191,P41440 2
Sulfur amino acid metabolism 0.4568041542451054 0.5759847096731533 0.5646255166887317 1.0 0.9508521983009722 9 Q13126 1
Rhoc gtpase cycle 0.4806493666543339 0.5745880829566601 0.565569913561613 1.0 0.9508521983009722 34 Q14739,P49257,Q96RT1,P41440,Q92888,Q5T8D3,Q13190 7
Rhov gtpase cycle 0.4690432215953511 0.5712138435885222 0.5678546952950803 1.0 0.9508521983009722 17 Q96KM6,P06753,Q14155 3
Gene and protein expression by jak stat signaling after interleukin 12 stimulation 0.4739326123080042 0.5593899595672621 0.5758956121964705 1.0 0.9561651821092768 24 P78417 1
Platelet homeostasis 0.4565739470186589 0.5582025094641563 0.5767061074684388 1.0 0.9563709615518275 11 Q16539,Q06124,Q14571,P23634,P30154 5
Slc mediated transmembrane transport 0.4724523756881378 0.5488542509055986 0.5831054762873815 1.0 0.9619803372509846 25 P36404,Q8TAD4,Q70HW3,Q8TB61,P12235 5
Mrna decay by 5 to 3 exoribonuclease 0.4483715093446209 0.5482189755982753 0.583541554183117 1.0 0.9619803372509846 8 Q96F86,Q9Y4Z0 2
Regulation of tnfr1 signaling 0.4458541136856797 0.5465745221957382 0.5846710767305026 1.0 0.9627030849711464 7 O15111,Q6GQQ9 2
Ovarian tumor domain proteases 0.449348248519216 0.5435666977667798 0.586739681661739 1.0 0.9638306327297198 9 Q7Z434,Q13546,Q6GQQ9 3
Maturation of sars cov 2 nucleoprotein 0.4400688520524179 0.5408511307043418 0.588610196993606 1.0 0.9657644339365054 5 Q99873,P49840 2
Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand 0.4669570329618523 0.511746609949521 0.6088283606887077 1.0 0.988459098414184 29 Q9UJW0,Q13561,O75935,Q02790,Q13451 5
Regulation of pyruvate dehydrogenase pdh complex 0.4387499708532359 0.507238823212224 0.61198725761844 1.0 0.9905063778046662 8 Q15118,P11177 2
Signaling by pdgfr in disease 0.4339521537817771 0.5057282523108231 0.6130474320465715 1.0 0.9905063778046662 6 O00459,Q6UN15 2
Signaling by alk 0.4357661440414556 0.5038657578268034 0.6143557145895417 1.0 0.9905063778046662 7 O00459,P19174 2
Interaction between l1 and ankyrins 0.427510335506111 0.4981590901579675 0.6183719145182831 1.0 0.9958289906635472 4 Q12955 1
Energy dependent regulation of mtor by lkb1 ampk 0.4380557560675275 0.4954523053243759 0.6202808810047653 1.0 0.9965989241518316 9 P49815,Q9Y478,P54646 3
Met activates ras signaling 0.42597321266535 0.491851799179735 0.6228241149953349 1.0 0.9983820393423491 4 Q96P70,P62993 2
Met activates rap1 and rac1 0.4292893639051029 0.4863998577732096 0.6266836913846463 1.0 1.0 6 P62993,P46108,Q96N67 3
Mitotic metaphase and anaphase 0.2814349266371328 0.4686121028869488 0.6393469247230197 1.0 1.0 139 Q9BS16,P28074,P30154,P25787,Q9UJX5,Q9UJX3,P28072,Q8WUX9,P49721,Q99436,Q9UJX4,O95067,Q8NBT2,P28070,Q14739,O00231,Q9UJX6,Q86XL3,Q13042 19
Tcr signaling 0.4514570027307062 0.468408691386534 0.6394923538215895 1.0 1.0 49 Q99436,O00231,P28074,P49427,O15111,O00459,P28072,P28070,P49721,P25787 10
Mitotic g1 phase and g1 s transition 0.367875878603667 0.467995068379512 0.6397881164168675 1.0 1.0 82 Q9Y619,P31350,P00374,P25787,O00231,P28074,P28072,Q5TKA1,Q9NRF9,P30154,P49721,P28070 12
Cell cycle checkpoints 0.2800989636412023 0.4641965082179859 0.6425069626868809 1.0 1.0 148 Q9BS16,P28074,P51530,P30154,P25787,Q96DE5,Q9UJX5,Q9UJX3,Q14191,P28072,P49721,Q9Y619,Q99436,Q9UJX4,O95067,P38398,Q8NBT2,P28070,O00231,Q2NKX8,Q9UJX6,Q9NWV8,Q13042,O96028 24
Wax and plasmalogen biosynthesis 0.4193146417445495 0.4551971898167836 0.6489673820381212 1.0 1.0 5 Q6IAN0,Q96K12,O15228,Q8WVX9 4
Establishment of sister chromatid cohesion 0.4256002890660564 0.4527576662860019 0.6507232502529043 1.0 1.0 8 Q8N3U4,Q8WVM7,Q7Z5K2,Q9NTI5,Q9UQE7 5
Signaling by retinoic acid 0.4305391855670928 0.4472925150828749 0.6546638705730001 1.0 1.0 11 Q15118,P11177,Q8NBN7 3
Cdt1 association with the cdc6 orc origin complex 0.452694097971861 0.4439671307719497 0.6570663482210997 1.0 1.0 42 Q99436,Q9Y619,Q9UBD5,P28074,O00231,P28072,P28070,P49721,P25787 9
Mtor signalling 0.4412477619491813 0.4421458333273608 0.6583836797769087 1.0 1.0 18 P49815,P62942,P54646 3
Transferrin endocytosis and recycling 0.4286289251734042 0.4394419700754264 0.6603413211243638 1.0 1.0 11 Q9Y487,P38606,P02786,P21281,Q9UI12,P61421,Q93050 7
Ros and rns production in phagocytes 0.422898823153243 0.4329795025304861 0.6650296610194038 1.0 1.0 9 Q9Y487,P38606,P21281,P61421,Q93050 5
Golgi cisternae pericentriolar stack reorganization 0.4243267307024422 0.4219213633754167 0.673082416099358 1.0 1.0 11 O95067,Q08379,Q9H8Y8 3
Nf kb activation through fadd rip 1 pathway mediated by caspase 8 and 10 0.412292610215468 0.4179796940756028 0.6759619637170191 1.0 1.0 6 O15111 1
Initiation of nuclear envelope ne reformation 0.434877796341682 0.4151348129597331 0.6780432158000107 1.0 1.0 18 Q14739,P14635,P50402,O95067,Q86XL3,P02545,Q14974 7
Cytoprotection by hmox1 0.4102598810811748 0.4050872567737569 0.6854133731596384 1.0 1.0 66 Q99436,P20674,Q96RS0,O00231,P28074,P53004,P09601,P30519,Q15648,P28072,Q14997,P28070,P49721,Q86X55,O75880,O75182,P25787 17
Glyoxylate metabolism and glycine degradation 0.4240447860015664 0.405041593385622 0.6854469375902994 1.0 1.0 13 Q9NR77 1
Rhog gtpase cycle 0.4452523226860517 0.4002248532799961 0.6889909107303278 1.0 1.0 36 Q14739,O15173,P49257,Q96RT1,Q6IAA8,P84095,Q86XL3,Q14185,Q7L576,Q13190 10
Regulated necrosis 0.4303831772947302 0.3903039245439704 0.6963118216145945 1.0 1.0 19 P41440,Q8WUX9 2
Apc c mediated degradation of cell cycle proteins 0.4167221950527561 0.3886645869279252 0.6975242821888545 1.0 1.0 62 Q9UJX4,P28074,O00231,Q9UJX5,Q9UJX3,Q9UJX6,P28072,P28070,Q13042,P49721,P25787 11
Insulin receptor recycling 0.4137417946021622 0.3880492347110723 0.6979795987441944 1.0 1.0 10 Q9Y487,P38606,P21281,Q9UI12,P61421,Q93050 6
Signaling by hedgehog 0.4226379318557446 0.3784629193327538 0.7050867348920455 1.0 1.0 58 Q99436,O00231,P28074,Q9GZP9,P28072,P28070,Q9UBV2,P49721,P25787 9
Asparagine n linked glycosylation 0.2747348703688553 0.3754553481059374 0.7073218485521822 1.0 1.0 119 Q9H3H5,Q92734,P49257,P61923,P24390,Q96FJ2,Q13190,Q14203,Q9H0U3,Q08379,Q2TAA5,P04843,O75935,Q9UBV2,P83436,Q9BUN8,Q8WTW3,Q9GZP9,O75340,Q96PC5,O60762,Q12955,Q9UJW0,P54920,Q13561,Q9Y678,O60476 27
Signalling to ras 0.3959590405161919 0.3741512701428736 0.7082917760794119 1.0 1.0 4 P62993,P12931 2
Fceri mediated nf kb activation 0.4381857724652172 0.3732282684416536 0.7089785585961774 1.0 1.0 43 Q99436,O00231,P28074,P49427,O15111,P28072,P28070,P49721,P25787 9
Glutathione conjugation 0.4160959122860327 0.3658744197341178 0.7144587849945929 1.0 1.0 14 P78417 1
Peroxisomal lipid metabolism 0.4117944879139317 0.3642535695944443 0.7156686677778221 1.0 1.0 12 Q08426,O15254,Q9BY49,Q5T8D3 4
Ngf stimulated transcription 0.3896966344678275 0.3605979260300933 0.7184000399438291 1.0 1.0 3 Q00535 1
Interleukin 12 signaling 0.431017478815624 0.3544417981989788 0.7230078146267438 1.0 1.0 27 Q13126,P78417 2
Neurotransmitter release cycle 0.3925233644859691 0.3520749333323593 0.7247820666608908 1.0 1.0 5 O75915,P51649,O94925,O14936 4
Heparan sulfate heparin hs gag metabolism 0.3957294600382778 0.345659602056907 0.7295985477333149 1.0 1.0 7 Q93063,Q96L58,P08236 3
Meiotic recombination 0.4124288541579859 0.3443436194750611 0.730587884122277 1.0 1.0 15 Q06609 1
Telomere c strand synthesis initiation 0.3877296792276571 0.3439266188155842 0.7309014727280332 1.0 1.0 4 P49643,P09884,Q9NYB0 3
Retrograde transport at the trans golgi network 0.4210740396081862 0.3407653150996358 0.7332802638104199 1.0 1.0 21 P83436,Q5VIR6,P54920,Q8WTW3,P20645 5
Death receptor signalling 0.4247507172071032 0.3405831811255309 0.7334173927587995 1.0 1.0 24 Q14155,O15111,Q6GQQ9,O14920,Q9H8V3 5
Sars cov infections 0.4028331457954166 0.3295816010269923 0.7417161267657797 1.0 1.0 64 P49354,P62942,P23458,Q9H0U3,Q99873,Q99720,P49356,P49841,Q02790,P49840,P21964,O60885,Q8WUX9 13
Aurka activation by tpx2 0.4267777090348595 0.329539314172673 0.7417480834019732 1.0 1.0 29 O95684,Q9H6D7,O75935,Q13561 4
Regulation of kit signaling 0.3802150547209572 0.3265740157234365 0.7439900993042021 1.0 1.0 3 P12931 1
Insertion of tail anchored proteins into the endoplasmic reticulum membrane 0.4016077869667197 0.3255069270592117 0.7447974408074742 1.0 1.0 12 O43681,P09601,Q13190 3
Late endosomal microautophagy 0.397260993546853 0.3254531187132982 0.7448381587404165 1.0 1.0 10 Q8WUX9 1
Uch proteinases 0.42772379233488 0.3241674718641657 0.7458112471850908 1.0 1.0 44 Q99436,O00231,P28074,Q8NB78,P28072,P28070,P49721,P25787 8
Degradation of axin 0.4286914166973489 0.3229286283519673 0.7467492945953302 1.0 1.0 37 P25787,O00231,P28074,P28072,P49721,P28070 6
Ca dependent events 0.3839001740678932 0.3209901697417783 0.7482178404638822 1.0 1.0 5 P10644 1
Activation of smo 0.3737939620292536 0.3138007261568596 0.7536723928316147 1.0 1.0 2 P48729 1
Cellular response to chemical stress 0.3656921103941187 0.3124886405837592 0.7546691946548028 1.0 1.0 77 Q99436,P20674,Q96RS0,P25787,O00231,P09601,P28074,O75182,P53004,P30519,Q15648,P28072,Q14997,Q16881,Q86X55,O75880,P49721,P28070 18
Collagen biosynthesis and modifying enzymes 0.3978366207972941 0.3115589070603368 0.7553757681389617 1.0 1.0 12 Q32P28,O60568 2
Recruitment of mitotic centrosome proteins and complexes 0.4228384908263198 0.3098015327629713 0.7567118859460287 1.0 1.0 30 Q14203,Q9H6D7,Q13561,O95684,O75935 5
Regulation of runx3 expression and activity 0.4258182363651381 0.3095370057109025 0.7569130668733055 1.0 1.0 38 P25787,O00231,P28074,P28072,P49721,P28070 6
Signaling by ntrk3 trkc 0.3779157726962243 0.3091939457529286 0.7571739990151567 1.0 1.0 4 P12931,P19174 2
Degradation of dvl 0.4248276378491807 0.3050631908638981 0.7603180251804844 1.0 1.0 38 P25787,O00231,P28074,P28072,P49721,P28070 6
Tnfr2 non canonical nf kb pathway 0.4231804998392532 0.2991823141570524 0.7648009428935119 1.0 1.0 42 P25787,O00231,P28074,O15111,P28072,P49721,P28070 7
Dectin 1 mediated noncanonical nf kb signaling 0.4231804998392533 0.2991823141570519 0.7648009428935123 1.0 1.0 42 P25787,O00231,P28074,O15111,P28072,P49721,P28070 7
Dual incision in gg ner 0.4151219479795727 0.2969317242283593 0.7665186354171205 1.0 1.0 25 Q9NRF9,P41440,Q92889,P32780 4
Cell cycle 0.2548689151736594 0.292802765122959 0.7696729145800987 1.0 1.0 312 Q9BS16,Q9H6D7,P28074,P41440,Q00534,Q9BRT9,Q5TKA1,P51530,P30154,P25787,Q14203,Q96DE5,P00374,Q08379,Q9UJX5,Q9UJX3,Q14191,P28072,O75935,Q06609,Q9NRF9,Q8WUX9,P49721,Q9Y619,Q99436,Q9UJX4,O95684,O95067,Q9BRX5,P38398,Q8NBT2,P28070,Q14739,P31350,O00231,Q13561,Q2NKX8,O94901,Q9UJX6,Q86XL3,Q9NWV8,O96028,Q13042 43
Non integrin membrane ecm interactions 0.3724696356275327 0.2905711801719692 0.7713793043378039 1.0 1.0 4 P05556,P12814,O14936 3
Syndecan interactions 0.3724696356275327 0.2905711801719692 0.7713793043378039 1.0 1.0 4 P05556,P12814,O14936 3
Rho gtpases activate iqgaps 0.3872074882995265 0.2892747942443678 0.772371099434487 1.0 1.0 10 P46940,P35222,Q86VI3,P35221,Q13885,Q9BUF5,P60953,P63000,P68371 9
Integrin cell surface interactions 0.3710041782283856 0.2856426442320537 0.7751518382358797 1.0 1.0 4 Q9Y624 1
Phosphorylation of emi1 0.3698894987488064 0.2819176637575445 0.7780066449441794 1.0 1.0 4 P14635,Q12834 2
Metalloprotease dubs 0.3718856985741017 0.2796120940481066 0.779775127371404 1.0 1.0 5 P38398 1
Cytosolic sensors of pathogen associated dna 0.3999151411399899 0.2768991848697726 0.7818575185127667 1.0 1.0 18 P49959,P19474,O15111,O14920,O14802 5
Interleukin 4 and interleukin 13 signaling 0.391008541693896 0.2719353261066084 0.7856717480861946 1.0 1.0 14 Q07820,P09601 2
Recruitment of numa to mitotic centrosomes 0.414787497759718 0.2706982499269918 0.7866231229307701 1.0 1.0 32 Q14203,Q9H6D7,Q13561,O95684,O75935 5
Met receptor recycling 0.3664807969276705 0.2706560642186996 0.7866555715237711 1.0 1.0 4 P62993,P46108 2
Asymmetric localization of pcp proteins 0.4168831081277038 0.2698206205159306 0.7872982581245522 1.0 1.0 38 P25787,O00231,P28074,P28072,P49721,P28070 6
Rho gtpases activate ktn1 0.3757405675085757 0.2664555604202356 0.7898883802147296 1.0 1.0 8 Q86UP2,Q07866,P33176,P84095,P60953,P63000,P61586 7
Interleukin 1 family signaling 0.4112542346195793 0.2588703851384188 0.7957352487123592 1.0 1.0 49 Q99436,O00231,P28074,O15111,Q9H3S7,P28072,P28070,P49721,P25787 9
Interleukin 12 family signaling 0.4100247255711864 0.2572240130368007 0.7970058477905144 1.0 1.0 30 Q13126,P78417 2
Negative regulators of ddx58 ifih1 signaling 0.3671965879648629 0.2554365948281684 0.7983859094069401 1.0 1.0 6 Q13526 1
Hur elavl1 binds and stabilizes mrna 0.3641744548286562 0.2543175283851681 0.7992502591861868 1.0 1.0 5 P35658,Q01105,P39687,Q15717 4
Regulation of ras by gaps 0.4131629027664462 0.2531240786138929 0.8001723325847974 1.0 1.0 39 P25787,O00231,P28074,P28072,P49721,P28070 6
Runx2 regulates bone development 0.3631564821081838 0.2510553564209334 0.8017713110820095 1.0 1.0 5 Q96PK6 1
Regulation of hmox1 expression and activity 0.4109615033866359 0.2489708591202308 0.8033833228172707 1.0 1.0 46 P25787,O00231,P28074,P09601,P28072,P49721,P28070 7
Prolactin receptor signaling 0.3552303860523015 0.2437533342627028 0.8074218641268982 1.0 1.0 3 Q06124,P63208 2
Mitophagy 0.3800304361968598 0.2413518251798376 0.8092824471064912 1.0 1.0 13 Q8N4H5,Q9NS69 2
Raf independent mapk1 3 activation 0.3640751252024027 0.2368384700306844 0.8127821056850331 1.0 1.0 7 P06493,Q99956,Q06124,P23458 4
Organic anion transporters 0.3492063492063489 0.2342990847988274 0.8147527963766141 1.0 1.0 2 Q9UBX3 1
Mitotic g2 g2 m phases 0.3081451440729366 0.2323703435828169 0.8162503809515236 1.0 1.0 90 Q99436,Q14203,P25787,O00231,P28074,Q13561,O95684,Q9H6D7,O95067,P28072,O75935,Q5TKA1,Q14997,P30154,P49721,P28070 16
Nuclear receptor transcription pathway 0.3571629541459015 0.2322230345860216 0.8163647877117701 1.0 1.0 5 P10589 1
Biological oxidations 0.4083362368298937 0.2318698207403808 0.8166391253320513 1.0 1.0 41 P16435,O43252,Q8TB61,P48507,Q5VT66,O43169,P78417 7
Scf skp2 mediated degradation of p27 p21 0.4076725248388023 0.229005567443942 0.8188645889130535 1.0 1.0 41 P25787,O00231,P28074,P28072,P49721,P28070 6
Homology directed repair 0.4059404392949375 0.2242849184669157 0.8225356106242072 1.0 1.0 45 P41440,Q14191,Q92889,Q06609,Q9NRF9,P38398,P51530 7
Formation of atp by chemiosmotic coupling 0.3650249584698956 0.2233879749461043 0.8232335624854039 1.0 1.0 9 P56385 1
M phase 0.2583012536187646 0.2192574858145936 0.8264494775141333 1.0 1.0 197 Q9BS16,Q9H6D7,Q6KC79,P28074,O95235,Q96FJ2,P30154,P25787,Q14203,Q96DE5,Q08379,P50402,Q9UJX5,Q9UJX3,P28072,O75935,Q8WUX9,P49721,Q99436,Q9UJX4,O95684,Q9H8Y8,O95067,Q14997,Q8NBT2,P28070,Q14739,Q96CW5,O00231,Q13561,Q2NKX8,Q9UJX6,Q86XL3,Q13042 34
Cell cycle mitotic 0.2540104259672214 0.2182184518153622 0.8272589090296902 1.0 1.0 266 Q9BS16,Q9H6D7,P28074,P41440,Q00534,Q9BRT9,Q5TKA1,P51530,P30154,P25787,Q14203,Q96DE5,P00374,Q08379,Q9UJX5,Q9UJX3,P28072,O75935,Q9NRF9,Q8WUX9,P49721,Q9Y619,Q99436,Q9UJX4,O95684,O95067,Q9BRX5,Q8NBT2,P28070,Q14739,P31350,O00231,Q13561,Q2NKX8,Q9UJX6,Q86XL3,Q13042 37
Anchoring of the basal body to the plasma membrane 0.3994329528195482 0.2160369572479114 0.8289589399880131 1.0 1.0 30 O95684,Q9H6D7,O75935,Q13561 4
Metabolic disorders of biological oxidation enzymes 0.3485756697586123 0.2148481558025754 0.8298857065689682 1.0 1.0 4 P48507 1
Immunoregulatory interactions between a lymphoid and a non lymphoid cell 0.3536280874267274 0.2130446763112315 0.831292115830601 1.0 1.0 6 Q5KU26 1
Cross presentation of soluble exogenous antigens endosomes 0.4028109522802052 0.2103700761618403 0.8333788458326192 1.0 1.0 38 P25787,O00231,P28074,P28072,P49721,P28070 6
Degradation of gli1 by the proteasome 0.4029418975525739 0.2088597908818013 0.8345576940873045 1.0 1.0 41 P25787,O00231,P28074,P28072,P49721,P28070 6
Cellular response to hypoxia 0.4026655363564201 0.2087620448085402 0.8346340023079886 1.0 1.0 39 P25787,O00231,P28074,P28072,P49721,P28070 6
Transcriptional regulation by runx3 0.4025296806210934 0.2070922701252555 0.8359377987935064 1.0 1.0 42 P25787,O00231,P28074,P28072,P49721,P28070 6
Pi3k akt signaling in cancer 0.3734556752098275 0.2055003032136806 0.8371812612230427 1.0 1.0 15 P12931,P49815,O15111,P84095,O00459,P49841,P49840,P62993 8
Iron uptake and transport 0.3812627628812104 0.2051188717570688 0.8374792523750021 1.0 1.0 19 P30519,P09601 2
Hedgehog on state 0.4017711913384058 0.2038785039053647 0.8384484436614803 1.0 1.0 42 P25787,O00231,P28074,P28072,P49721,P28070 6
Nonhomologous end joining nhej 0.373730894086395 0.1996146014070841 0.8417820073391633 1.0 1.0 16 P38398,O96028 2
Metabolism of steroids 0.3996490674428182 0.1995266211609316 0.8418508213070774 1.0 1.0 47 Q14739,Q96RS0,Q9UBM7,Q9BWD1,Q15392,P38435,Q15125 7
Fc epsilon receptor fceri signaling 0.3939652331360495 0.1961738071360264 0.8444741285923678 1.0 1.0 54 Q99436,O00231,P28074,P49427,O15111,O00459,P28072,P28070,P49721,P25787 10
Stabilization of p53 0.3991744517352432 0.1931618066196516 0.846832249290673 1.0 1.0 41 P25787,O00231,P28074,P28072,P49721,P28070 6
Tbc rabgaps 0.3670838223916114 0.1923050721625289 0.8475032455401459 1.0 1.0 14 Q9UJY4,P49815,Q9UJY5 3
Degradation of beta catenin by the destruction complex 0.3970051073313558 0.1897649469092088 0.8494933250507877 1.0 1.0 48 Q99436,O00231,P28074,P20618,P49841,P28072,Q14997,P28070,P49721,P30154,P25787 11
Disorders of transmembrane transporters 0.3506191379559786 0.1877863822340153 0.8510441112608027 1.0 1.0 76 Q99436,Q9BUN8,O00231,P28074,Q9GZP9,P28072,P28070,Q9UBV2,P49721,P25787 10
Antigen processing cross presentation 0.3931399165241099 0.1877369487965173 0.8510828642732513 1.0 1.0 53 Q99436,O00231,P28074,Q9UIQ6,O15111,Q12846,P20618,O14920,P28072,Q03518,Q14997,P28070,P49721,P25787 14
Ire1alpha activates chaperones 0.3852131853914387 0.1856866187828066 0.8526905224888728 1.0 1.0 25 Q14203,Q9UBS4,Q13217,P43307,P49840,P61421,Q9NWM8 7
Collagen formation 0.3642192920751804 0.1834942957889023 0.8544101940932713 1.0 1.0 14 Q32P28,O60568 2
Dna double strand break response 0.3749336030277685 0.1783992409482522 0.858409445378344 1.0 1.0 20 P49959,O00213,Q9NWV8,Q99496,P38398,O96028 6
Programmed cell death 0.253474643423171 0.1743151762239553 0.8616177729315804 1.0 1.0 103 P49354,P08670,P25787,O00231,P28074,P41440,O00560,P28072,Q8WUX9,P49721,P28070 11
Metabolism of polyamines 0.3937504250087931 0.1729257131546227 0.8627098199476364 1.0 1.0 39 P25787,O00231,P28074,P28072,P49721,P28070 6
Generation of second messenger molecules 0.3361370716510961 0.1714576596012733 0.8638639201350111 1.0 1.0 5 Q13177,Q13153,Q16512,P19174 4
Regulation of runx2 expression and activity 0.3934936416581202 0.169525994610641 0.8653829275199434 1.0 1.0 43 P25787,O00231,P28074,P28072,P49721,P28070 6
G2 m checkpoints 0.3039949104386812 0.163906743827065 0.8698045580968556 1.0 1.0 89 Q9Y619,Q99436,P25787,O00231,P28074,O95067,Q14191,P28072,O96028,P38398,P51530,P49721,P28070 13
Tnf signaling 0.3395207240865463 0.1494219430427686 0.8812206980503976 1.0 1.0 9 O15111,Q6GQQ9 2
Sensing of dna double strand breaks 0.3267584129025069 0.1471474578757104 0.8830156315738127 1.0 1.0 5 P49959 1
Darpp 32 events 0.3379075656752131 0.1451795302526281 0.8845691271885272 1.0 1.0 9 P30154 1
Fcgamma receptor fcgr dependent phagocytosis 0.3831984021982774 0.1440386474635167 0.8854699515651421 1.0 1.0 34 Q7L576,O00459,Q8IV08,Q9UQB8 4
Mitotic telophase cytokinesis 0.3456424717438024 0.1371404306811753 0.8909197952982171 1.0 1.0 13 Q8N3U4,Q8WVM7,Q7Z5K2,Q6KC79,Q9NTI5,Q9Y6X3,O95235,Q9UQE7 8
Extension of telomeres 0.3769518643658412 0.1362005718176472 0.8916627231358938 1.0 1.0 30 Q14191,P41440 2
Regulation of mecp2 expression and activity 0.336736809116246 0.1348500495739376 0.8927304333650103 1.0 1.0 10 Q14739 1
Rhou gtpase cycle 0.360564891731992 0.1343887749605382 0.8930951574010169 1.0 1.0 20 O00459,Q14155,Q13813,P12931 4
G1 s dna damage checkpoints 0.3845268208730231 0.1343741762497559 0.8931067007875575 1.0 1.0 42 P25787,O00231,P28074,P28072,P49721,P28070 6
Signaling by ptk6 0.3462961266453926 0.1321287911330565 0.8948824235190525 1.0 1.0 14 Q8IZL8,P46108,Q07666,O75525 4
Interleukin 1 signaling 0.3838546031544821 0.1314562920994407 0.8954143603089488 1.0 1.0 46 Q99436,O00231,P28074,O15111,P28072,P28070,P49721,P25787 8
Protein protein interactions at synapses 0.3434284799782648 0.1245295721372502 0.9008959874303596 1.0 1.0 14 Q9Y2J2,P11171,Q14168,P41440,O95197 5
Auf1 hnrnp d0 binds and destabilizes mrna 0.3806354104022628 0.119680195852603 0.9047364890045207 1.0 1.0 42 P25787,O00231,P28074,P28072,P49721,P28070 6
Vitamin b5 pantothenate metabolism 0.3113840569082636 0.1185609854518808 0.905623176367596 1.0 1.0 4 Q13057 1
Recycling of eif2 gdp 0.3206672776678236 0.1174477791327962 0.9065052237582464 1.0 1.0 7 P49770,Q13144,Q9UI10 3
Orc1 removal from chromatin 0.3782064236619974 0.1173698599363063 0.9065669672503518 1.0 1.0 52 Q9Y619,O00231,P28074,P28072,P28070,P49721,P25787 7
Negative regulation of notch4 signaling 0.3790246296308361 0.1161215113846769 0.9075562405213295 1.0 1.0 40 P25787,O00231,P28074,P28072,P49721,P28070 6
Negative regulation of mapk pathway 0.3264377242089031 0.1095514047733677 0.9127651519644676 1.0 1.0 10 Q99956,P30154 2
Signaling by leptin 0.2987861811391202 0.1067513311106168 0.9149862588978572 1.0 1.0 2 Q06124 1
Regulation of plk1 activity at g2 m transition 0.3712845326690401 0.1006918914995013 0.919795048305386 1.0 1.0 35 Q9H6D7,Q13561,O95684,O95067,O75935 5
Ra biosynthesis pathway 0.3011522890065427 0.0970182293053611 0.9227119178476416 1.0 1.0 4 Q9HBH5,Q8TC12,Q8NBN7 3
Interleukin 35 signalling 0.2989722827779535 0.0927092713617889 0.9261345312554032 1.0 1.0 4 P42224,P27824,P23458 3
Interleukin 27 signaling 0.2989722827779535 0.0927092713617889 0.9261345312554032 1.0 1.0 4 P42224,P27824,P23458 3
Post translational modification synthesis of gpi anchored proteins 0.305577454160133 0.0918572224923136 0.9268114792159684 1.0 1.0 6 O60762 1
Transcriptional regulation by mecp2 0.3289546580040526 0.0888596971710329 0.9291934137947988 1.0 1.0 14 Q14739,Q13451 2
Cyclin a cdk2 associated events at s phase entry 0.3724040180690334 0.0873131419862121 0.9304226081217222 1.0 1.0 46 O00231,P28074,P28072,Q5TKA1,P28070,P49721,P25787 7
Rhoh gtpase cycle 0.3498415359857161 0.0778219531860394 0.9379696832882825 1.0 1.0 25 Q9BXB4,Q9UNZ2,Q8WWQ0,P41240,P02786,Q658Y4,Q6IAA8,P27105,O75323 9
Epha mediated growth cone collapse 0.311306899829573 0.0764589539132199 0.93905396837636 1.0 1.0 10 P60660,P12931,P35580,P35579,Q7Z406 5
Amyloid fiber formation 0.3079061828508443 0.0761948388114943 0.939264088786166 1.0 1.0 9 Q9UJY5 1
Senescence associated secretory phenotype sasp 0.3449150330140781 0.0751765517950829 0.9400742405079732 1.0 1.0 23 Q9UJX4,Q00534,Q9UJX5,Q9UJX3,Q9UJX6,Q13042 6
E3 ubiquitin ligases ubiquitinate target proteins 0.3250000000000098 0.073710400347131 0.9412408230236124 1.0 1.0 15 Q9BUN8,Q14527,P04439,Q92541,P78527,O75381,Q9GZS3,Q8N7H5,Q5VTR2,Q6P1J9,P68036,Q6PD62,O75150,P55072 14
Ncam signaling for neurite out growth 0.2959839197111021 0.0733711974191216 0.9415107369329964 1.0 1.0 6 Q13813,P12931 2
Caspase mediated cleavage of cytoskeletal proteins 0.2974774805642578 0.0694896007823551 0.9445999100182008 1.0 1.0 7 P35611,Q13813,P08670 3
Translation of sars cov 1 structural proteins 0.2972516344937413 0.0690779074528725 0.9449276063124592 1.0 1.0 7 P49840 1
Ion channel transport 0.3549085571037064 0.0689591085018349 0.9450221686663828 1.0 1.0 30 Q9Y487,P38606,P35670,P05026,P16615,P27105,P51798,P23634,P98194,P21281,Q15904,Q9UI12,Q9H4A3,P61421,Q9HD20,Q93050,Q13546 17
Pi metabolism 0.3265932399085274 0.0652338160622328 0.9479878371347596 1.0 1.0 17 Q9UBF8,Q8NCE2,Q01968,O00459,Q10713,Q96T51,Q8N9F7,Q99570 8
Signaling by met 0.3258394205016559 0.0635823169211053 0.9493028123009972 1.0 1.0 17 Q96P70,Q06124,Q96N67,P12931,P62993,P46108 6
Vesicle mediated transport 0.2466549708354406 0.0635444506628681 0.949332964230774 1.0 1.0 258 Q9UJY5,Q9P2W9,Q92734,P49257,P61923,P54646,P20645,Q99523,P24390,Q8WTV0,O95721,Q13190,Q14203,Q5VIR6,O15260,Q9Y478,Q9Y5X3,Q9UPT5,Q08379,Q8TBA6,O00461,O75935,Q8WUX9,P11717,O75976,P83436,Q9UIQ6,Q8WTW3,Q9NZZ3,Q96PC5,P51809,Q12955,Q9UJW0,P54920,Q13561,Q5KU26,P49815,O60333,Q01968,Q9UBC2,Q9UJY4,O60476 42
Dna repair 0.2477801218847512 0.0608776677181036 0.9514566350303522 1.0 1.0 116 Q8N9N2,Q99496,P41440,P32780,Q14191,Q92889,Q9H1I8,Q06609,P51530,Q9NRF9,O96028,Q9NWV8,P38398,O75925,P54725 15
Lagging strand synthesis 0.3302568761922044 0.0562965175190931 0.9551055930542798 1.0 1.0 20 P41440 1
Signaling by notch4 0.3621970292385852 0.0553916691084839 0.955826432737758 1.0 1.0 42 P25787,O00231,P28074,P28072,P49721,P28070 6
Purine salvage 0.2781931464174502 0.0502609773817484 0.9599144199835464 1.0 1.0 5 P00813,P00492,P55263,P07741 4
Mapk6 mapk4 signaling 0.3595653413923319 0.0416418367751379 0.9667842212266852 1.0 1.0 50 P25787,O00231,P28074,P28072,P49721,P28070 6
Host interactions of hiv factors 0.2654130968150359 0.0413234134149906 0.9670380678038526 1.0 1.0 95 P25787,O00231,P28074,P28072,Q6VY07,P12235,P49721,P28070 8
Unwinding of dna 0.2912326310002084 0.0400380834533507 0.9680627644172596 1.0 1.0 10 Q9BRX5 1
Nucleotide salvage 0.2783665835411573 0.0383512032707996 0.9694076664818916 1.0 1.0 7 P55263,P00492,Q9BZX2,P00813,P04183,P07741 6
Hedgehog off state 0.3554097480910983 0.0282515100784181 0.9774615544974689 1.0 1.0 52 Q99436,O00231,P28074,P28072,P28070,P49721,P25787 7
Pcp ce pathway 0.3555467630401848 0.0276932468766982 0.9779068098512194 1.0 1.0 48 P25787,O00231,P28074,P28072,P49721,P28070 6
Apoptotic factor mediated response 0.2638320442721643 0.0250473050089977 0.9800172314886588 1.0 1.0 6 Q9NR28 1
Clec7a dectin 1 signaling 0.3542342992282449 0.0231061229927052 0.9815656215493916 1.0 1.0 50 Q99436,O00231,P28074,P49427,O15111,P28072,P28070,P49721,P25787 9
Selective autophagy 0.3359718140531246 0.0164138883133191 0.9869041999704536 1.0 1.0 31 P08670,Q9NS69,P54646,P21796,Q8N4H5 5
Attachment of gpi anchor to upar 0.2416692619121797 0.0131950035354241 0.989472215895679 1.0 1.0 4 Q969N2,Q92643,Q9H490 3
Intracellular signaling by second messengers 0.2872616648327509 0.0117993413704136 0.9905857061434028 1.0 1.0 88 P28074,O75832,Q14571,P49841,P30154,Q8WXI9,P25787,O95983,P12931,P84095,P20618,P46934,O00459,P28072,P49721,Q99436,P19174,P52292,P10644,Q14997,P49840,P62993,P28070,Q06124,O00231,P49815,O15111,Q6IAA8,Q99496 29
Sema4d in semaphorin signaling 0.2658381218781522 0.0109570260022477 0.9912577330483848 1.0 1.0 9 Q7Z406,P35580,P60660,P35579 4
Runx1 regulates transcription of genes involved in differentiation of hscs 0.3479367988620763 0.0100094926551852 0.9920137137067756 1.0 1.0 43 P25787,O00231,P28074,P28072,P49721,P28070 6
Copi mediated anterograde transport 0.3477307708795423 0.0032866571768934 0.9973776317030932 1.0 1.0 54 P83436,Q12955,Q9UJW0,P54920,Q13561,Q08379,Q8WTW3,P61923,O75935,P24390,Q13190 11
Phase ii conjugation of compounds 0.3189346881140544 0.002391530237144 0.99809183676602 1.0 1.0 26 P48507,O43252,P78417 3
Ub specific processing proteases 0.3253355472344958 0.0010922204842384 0.999128534311902 1.0 1.0 73 Q99436,O00231,P28074,Q8IXI2,P28072,P28070,Q96K76,Q14997,Q70CQ2,Q9UPU5,P21796,P49721,P25787 13