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interpro_active_site/advanced/idx2term.json

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+{}

interpro_active_site/basic/idx2term.json

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+{"0": "Serine/threonine-protein kinase, active site [IPR008271]"}

interpro_active_site/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:e33755e05b658b2559e36c368513f3706b1e590ed3f207cf72160876240d737d
+size 80472

interpro_active_site/df_merge.tsv

@@ -0,0 +1 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_active_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3425,
+    "annotations_size": 58,
+    "title": "Average number of proteins per term",
+    "value": 2.810344827586207
+}

interpro_active_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C137/C137_val_log2fc"}

interpro_active_site/result.tsv

@@ -0,0 +1,10 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Protein-tyrosine phosphatase, active site [IPR016130]	0.6416868398401682	1.957887304439852	0.0502432379321107	0.9497056881012432	0.2081505571473158	9	Q13614,P51452,O60942,Q8NCE2	4
+Ubiquitin-conjugating enzyme, active site [IPR023313]	0.6727591129607006	1.3943011832104686	0.1632266737822698	0.9999675470627468	0.3492556166045542	5	P49427,Q16763,P68036	3
+Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]	0.8206251825883737	1.382176629572631	0.166917474085116	0.9999748866032157	0.3492556166045542	2	Q9NQ88	1
+Serine/threonine-protein kinase, active site [IPR008271]	0.3151490896455099	1.2911593670755273	0.1966484215949067	0.9999969483988062	0.3758079535056106	60	Q99570,P36507,P33981,P24941,P51617,Q16512,Q99640,P48729,Q00534,Q02750,Q9H4A3,Q14012,P17612,Q96KB5,P19525,P31751,P49841,Q13177,Q13546,Q99986,Q00535,Q96SB4,P10398,P19784,O14965	25
+Nucleoside diphosphate kinase, active site [IPR023005]	0.6925859678706816	0.8455107443146228	0.3978257363552182	0.9999999999998326	0.5627778709415282	3	P15531	1
+L-lactate dehydrogenase, active site [IPR018177]	0.6409582237803145	0.6586046987034349	0.5101496448293326	1.0	0.6164308208354435	2	P00338	1
+Ubiquitin-activating enzyme E1, Cys active site [IPR033127]	0.6202273558788243	0.5885815044572303	0.5561420441080656	1.0	0.6180648248007394	3	Q9UBT2	1
+Cysteine peptidase, cysteine active site [IPR000169]	0.4641917567962721	0.4250474372299238	0.6708020941196859	1.0	0.7204911381285516	4	Q13867,P17655,P53634	3
+Tyrosine-protein kinase, active site [IPR008266]	0.3692982456140335	0.2131592840952171	0.8312027249969631	1.0	0.876541055451343	5	P41240,Q05397,P07948,Q13308	4

interpro_active_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenosine/AMP deaminase active site [IPR006650]", "Adenylosuccinate synthase,  active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Coenzyme A transferase active site [IPR004164]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glutaredoxin active site [IPR011767]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycoside hydrolase, family 2, active site [IPR023232]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Lipase, GDXG, putative serine active site [IPR033140]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Peptidase family C14A, His active site [IPR016129]", "Peptidase family C14A, cysteine active site [IPR033139]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]", "Uracil-DNA glycosylase, active site [IPR018085]"], "available_proteins": ["ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADSS", "AKT2", "AKT3", "AMPD2", "APEH", "ARAF", "ATP5A1", "ATP5B", "ATP6V1A", "ATP6V1B2", "AURKA", "AURKB", "BLMH", "CAMK1", "CAMK2G", "CAPN1", "CAPN2", "CASP3", "CDC34", "CDC42BPB", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CHEK2", "CHUK", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CTSA", "CTSC", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLRX", "GLUD1", "GSK3A", "GSK3B", "GSR", "GUSB", "HADHB", "HMGCL", "HMGCS1", "IKBKB", "IRAK1", "LDHA", "LDHB", "LONP1", "LYN", "MAP2K1", "MAP2K2", "MAP2K6", "MAP3K4", "MAP4K4", "MAPK1", "MARK3", "MDH1", "MDH2", "MTMR14", "MTMR2", "MTMR6", "NCEH1", "NEK1", "NEK9", "NME1", "NME2", "NME6", "OXCT1", "PAK2", "PBK", "PGAM1", "PIK3R4", "PKM", "PKMYT1", "PKN1", "PKN2", "PLK1", "PREP", "PRKAA1", "PRKAA2", "PRKACA", "PRKCA", "PRKCD", "PRPF4B", "PTK2", "PTK7", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "RIPK1", "RNASET2", "RNGTT", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SUCLG1", "TALDO1", "TIGAR", "TLK2", "TOP1", "TPI1", "TPP2", "TTK", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2K", "UBE2L3", "UBE2M", "UBE2S", "UMPS", "UNG", "VRK1", "VRK2", "WNK1", "YES1"], "leading_proteins": ["AKT2", "ARAF", "AURKA", "BLMH", "CAMK1", "CAPN2", "CDC34", "CDK2", "CDK5", "CDK6", "CSK", "CSNK1A1", "CSNK2A2", "CTSC", "DUSP3", "EIF2AK2", "GSK3B", "IRAK1", "LDHA", "LYN", "MAP2K1", "MAP2K2", "MTMR14", "MTMR2", "NME1", "PAK2", "PBK", "PIK3R4", "PKMYT1", "PKN1", "PRKACA", "PTK2", "PTK7", "RIPK1", "RNGTT", "SRPK1", "TIGAR", "TTK", "UBA2", "UBE2L3", "UBE2S", "VRK1", "WNK1"]}

interpro_binding_site/advanced/idx2term.json

@@ -0,0 +1 @@
+{}

interpro_binding_site/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Protein kinase, ATP binding site [IPR017441]", "1": "EF-Hand 1, calcium-binding site [IPR018247]"}

interpro_binding_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:a8510f9791cdec8b5f7d3dee0de9bb1fa3d45f91635ba2876ae263682c7135ef
+size 78939

interpro_binding_site/df_merge.tsv

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+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_binding_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3425,
+    "annotations_size": 31,
+    "title": "Average number of proteins per term",
+    "value": 5.225806451612903
+}

interpro_binding_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C137/C137_val_log2fc"}

interpro_binding_site/result.tsv

@@ -0,0 +1,7 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Protein kinase, ATP binding site [IPR017441]	0.3472202529980679	1.6333648531826344	0.1023922844292219	0.9648695359272575	0.2246979244852183	59	P36507,P33981,Q13131,Q13043,P24941,P51617,Q16512,Q99640,Q16539,P48729,Q00534,Q02750,Q9P289,Q14012,P17612,P19525,P31751,P49841,O75116,Q13177,Q99986,Q00535,P41240,Q96SB4,P10398,Q9NYV4,O14965,P19784,O95747,P06493	30
+Beta tubulin, autoregulation binding site [IPR013838]	0.6693695146902517	1.5952209706813745	0.1106628308682551	0.973633058587336	0.2246979244852183	6	P07437,Q9BUF5,Q9BVA1	3
+PPM-type phosphatase, divalent cation binding [IPR000222]	0.7437919953257408	1.0628816734539972	0.287835614950473	0.9999730854091206	0.4461452031732332	2	O15355	1
+EF-Hand 1, calcium-binding site [IPR018247]	0.2653843515626173	0.5985928774308346	0.5494444068901911	0.9999999999815412	0.7096990255664969	41	Q9UBC2,Q96AY3,O43852,P41208,P0DP25	5
+IQ motif, EF-hand binding site [IPR000048]	0.3369206327959516	0.4717925153631536	0.6370748938001094	0.9999999999999774	0.7595892964539765	12	Q15051	1
+Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]	0.3169734151329206	0.0414637211497177	0.966926214296137	1.0	0.9991570881060082	2	Q9UQ80	1

interpro_binding_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Coenzyme A transferase binding site [IPR004163]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]", "Ureohydrolase, manganese-binding site [IPR020855]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "AKT2", "AKT3", "APEX1", "ARAF", "ARG2", "AURKA", "AURKB", "BPNT1", "CALM3", "CALU", "CAMK1", "CAMK2G", "CAPN1", "CAPN2", "CAPNS1", "CDC42BPB", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CETN2", "CHUK", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A2", "CYB5B", "DBT", "DLAT", "DLST", "DST", "EHD1", "EHD4", "EIF2AK2", "EPS15", "EPS15L1", "FKBP10", "FKBP14", "FKBP7", "FKBP9", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3A", "GSK3B", "HK1", "HK2", "HMBS", "IDE", "ILKAP", "IQCB1", "IQGAP1", "IQGAP2", "IQGAP3", "IRAK1", "ITSN2", "LETM1", "LYN", "MACF1", "MAP2K1", "MAP2K2", "MAP2K6", "MAP3K4", "MAP4K4", "MAPK1", "MAPK14", "MARK3", "MCCC1", "METAP2", "MICU1", "MYH10", "MYH14", "MYH9", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "NEK1", "NRDC", "NUCB1", "NUCB2", "OXCT1", "OXSR1", "PA2G4", "PAK2", "PAK4", "PC", "PCCA", "PDCD6", "PDHX", "PEF1", "PGD", "PKMYT1", "PKN1", "PKN2", "PLCG1", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1G", "PRKAA1", "PRKAA2", "PRKACA", "PRKCA", "PRKCD", "PRKCSH", "PSAT1", "PTK2", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "S100A11", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "STK26", "STK4", "TKT", "TLK2", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "UBE3C", "UQCRC2", "USP32", "VRK1", "YES1"], "leading_proteins": ["AKT2", "ARAF", "AURKA", "CALM3", "CALU", "CAMK1", "CDK1", "CDK12", "CDK2", "CDK5", "CDK6", "CETN2", "CSK", "CSNK1A1", "CSNK2A2", "EIF2AK2", "EPS15L1", "FKBP10", "GSK3B", "IQCB1", "IRAK1", "MAP2K1", "MAP2K2", "MAPK14", "OXSR1", "PA2G4", "PAK2", "PKMYT1", "PKN1", "PPM1G", "PRKAA1", "PRKACA", "ROCK2", "SRPK1", "STK26", "STK4", "TTK", "TUBB", "TUBB2B", "TUBB6", "VRK1"]}

interpro_conserved_site/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "Proteasome beta-type subunit, conserved site [IPR016050]"}

interpro_conserved_site/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Proteasome beta-type subunit, conserved site [IPR016050]", "1": "14-3-3 protein, conserved site [IPR023409]", "2": "Chaperonin TCP-1, conserved site [IPR002194]", "3": "DnaJ domain, conserved site [IPR018253]", "4": "ATPase, AAA-type, conserved site [IPR003960]"}

interpro_conserved_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:e158db3618cef30fe4aac957714c8c62811967b0f49d640fc99d83e24d674b89
+size 113746

interpro_conserved_site/df_merge.tsv

@@ -0,0 +1,3 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+Proteasome beta-type subunit, conserved site [IPR016050]	7	8	3.102730848402799	0.0019174393840755	3.7135922330097086	7.970873786407767	1.4913184573846054	0.1902243906475925	1.515457478026574	0.1681602725795027	1.0170822776023185	0.2455850375425174	1.0	1.148254609278584e-05	9.839858993160587e-05	5.22260781759681e-10	1.22573214543153e-09
+Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]	1	5	2.343781263498936	0.0190893630126129	1.8349514563106797	4.495145631067961	-0.0268416016144192	0.3268992301433215	1.18113888908689	0.4999764345469411	1.4254920509394828	0.309635855483207	1.0	0.0002150789234385	0.0008973897437505	0.0056136137273067	0.0214122317398669

interpro_conserved_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3425,
+    "annotations_size": 284,
+    "title": "Average number of proteins per term",
+    "value": 2.8450704225352115
+}

interpro_conserved_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C137/C137_val_log2fc"}

interpro_conserved_site/result.tsv

@@ -0,0 +1,41 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Proteasome beta-type subunit, conserved site [IPR016050]	0.9075212174422068	3.102730848402799	0.0019174393840755	0.4202020086471177	0.0599907167853119	8	P20618,Q99436,P49721,P28072,P28070,P28074,P49720	7
+Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]	0.8964725207226569	2.343781263498936	0.0190893630126129	0.9958047088208096	0.0903563182597015	5	P48735	1
+Chromo domain, conserved site [IPR023779]	0.6953962894123901	1.9094353254936849	0.056205957388544	0.9999999266949666	0.1666197344765188	7	Q12873,P83916,O14646	3
+14-3-3 protein, conserved site [IPR023409]	0.7130739982451005	1.7945239204549257	0.072729584127241	0.9999999995140196	0.1948887571757021	6	Q04917,P61981,P27348,P63104,P31946	5
+Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]	0.6703289396348417	1.7901127422580114	0.0734357887562169	0.9999999996085754	0.1948887571757021	7	Q13535,P42356,Q96Q15	3
+Profilin conserved site [IPR027310]	0.8816827344434759	1.6377613549839911	0.1014714860278738	0.9999999999999364	0.252788614315054	2	P07737	1
+Tubulin, conserved site [IPR017975]	0.6217076785885784	1.5553138952532628	0.119871329625719	0.9999999999999998	0.2689442811375302	7	P07437,Q9BUF5,Q9BVA1,P04350	4
+Clathrin adaptor complex, small chain [IPR000804]	0.8695854771094825	1.52722794727679	0.1267043391331583	1.0	0.2811252524516951	3	P61923	1
+Macrophage migration inhibitory factor, conserved site [IPR019829]	0.8340636868244257	1.4384545034654566	0.1503051375826967	1.0	0.3185571572648198	2	P30046	1
+Purine phosphorylase, family 2, conserved site [IPR018099]	0.8215016067776933	1.3858457551124714	0.1657940075434263	1.0	0.3429363562441447	2	Q13126	1
+Chaperonin TCP-1, conserved site [IPR002194]	0.546551328193488	1.363931884570491	0.1725890046517295	1.0	0.3476260802914269	8	P17987,P50991,P78371,P40227,P48643,P49368	6
+Phosphoribosyl pyrophosphate synthetase, conserved site [IPR000842]	0.8042652643879697	1.313739977431123	0.188933722703636	1.0	0.3708282238596381	2	P11908	1
+Ribosomal protein S5, N-terminal, conserved site [IPR018192]	0.7890739117732978	1.2503309987817213	0.2111786590968121	1.0	0.3971837032019513	2	P15880	1
+HMG box A DNA-binding domain, conserved site [IPR017967]	0.7940766533662522	1.2329936549372809	0.2175781314599481	1.0	0.4065275614120083	3	O15347	1
+DnaJ domain, conserved site [IPR018253]	0.4335661736102129	0.9384322457496836	0.3480223211091973	1.0	0.5552715685113034	11	O60884,Q99543,P25685,P31689,Q8WXX5	5
+Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]	0.7002629272568077	0.8867261222231335	0.3752263708922703	1.0	0.582318520947567	2	P29692	1
+Phosphorylase pyridoxal-phosphate attachment site [IPR035090]	0.679228746713423	0.8038738130779437	0.4214698551143501	1.0	0.6201939836915825	2	P06737	1
+Mini-chromosome maintenance, conserved site [IPR018525]	0.4910603353386935	0.7746965794222682	0.4385189727151442	1.0	0.6321796357923907	6	P33992,P25205,P33991,P49736	4
+Alpha-D-phosphohexomutase, conserved site [IPR016066]	0.6580701459307636	0.7198757755861208	0.4716014842636775	1.0	0.6630436709449723	3	Q96G03	1
+Dynamin, GTPase region, conserved site [IPR019762]	0.6380368098159555	0.6478680578571997	0.5170702919557322	1.0	0.6996495351290343	2	P50570	1
+F-actin capping protein, alpha subunit, conserved site [IPR017865]	0.6348232544551644	0.6361233663541203	0.5246960167513768	1.0	0.7048137250386391	2	P47755	1
+Ubiquitin interacting motif [IPR003903]	0.5183673774310886	0.618750322545884	0.5360808530865016	1.0	0.7048137250386391	4	Q92783	1
+CBX family C-terminal motif [IPR033773]	0.6222611744084292	0.5909069262744483	0.5545827849185287	1.0	0.709466265391271	2	Q9HC52	1
+Cullin, conserved site [IPR016157]	0.4781428275970755	0.5669855506341906	0.5707239986469617	1.0	0.7140335489680049	5	Q93034,Q13620,Q13616	3
+D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]	0.60998387510767	0.5545109882001815	0.5792291877248656	1.0	0.7183453681828028	3	Q9GZZ9	1
+Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]	0.5980134385042414	0.50710625631177	0.6120802654854756	1.0	0.7391093833197412	2	Q00796	1
+FERM conserved site [IPR019747]	0.3503863265326897	0.4704418822879731	0.6380393472683958	1.0	0.7613578765723715	10	P15311,P26038,Q9Y4F1,Q9Y2J2	4
+GHMP kinase, ATP-binding, conserved site [IPR006203]	0.5749342681858133	0.4322588137452762	0.6655533177433182	1.0	0.7843034947680596	2	P51570	1
+Glycoside hydrolase, family 29, conserved site [IPR018526]	0.5717207128250144	0.4222607334351904	0.6728347158481678	1.0	0.7896076830614862	2	P04066	1
+GTP1/OBG, conserved site [IPR006074]	0.5676307332749164	0.4096948780412297	0.6820297878206576	1.0	0.7971047725969825	2	P55039	1
+Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]	0.5600350569675843	0.3868437670782049	0.6988718734471102	1.0	0.8075680221057465	2	Q9NQW7	1
+DNA-directed DNA polymerase, family B, conserved site [IPR017964]	0.5597429155711482	0.3859777518957347	0.6995131459084987	1.0	0.8075680221057465	2	P28340	1
+Phosphofructokinase, conserved site [IPR015912]	0.5405857310569657	0.3456952406007333	0.729571761449691	1.0	0.8371996427526305	3	P08237	1
+Aldo/keto reductase, conserved site [IPR018170]	0.5384165936313292	0.325461169286839	0.7448320666528603	1.0	0.8427581949378976	2	P15121	1
+Fructose-bisphosphate aldolase class-I active site [IPR029768]	0.5243938066024102	0.2887301462622583	0.7727878913541775	1.0	0.8640620517503401	2	P04075	1
+D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]	0.3849751534638996	0.2013123589545192	0.8404543393399684	1.0	0.9215792755696952	4	O43175,Q13363,Q9UBQ7	3
+Ribosomal protein S9, conserved site [IPR020574]	0.4279871457785641	0.1093389907274998	0.9129336218370956	1.0	0.985829462364012	2	P62249	1
+ATPase, AAA-type, conserved site [IPR003960]	0.1998748802849937	0.0636968040562368	0.9492116495747842	1.0	0.9964872988726112	19	P62195,Q9UN37,P62333,Q15645,O75351,P17980	6
+Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331]	0.3682408310382033	0.0609616675819248	0.9513897370871852	1.0	0.9964872988726112	3	Q9H8V3	1
+Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]	0.3204791118901499	0.0421760429341406	0.9663583605316336	1.0	1.0	2	P06730	1

interpro_conserved_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3'5'-cyclic nucleotide phosphodiesterase, conserved site [IPR023174]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Aldose 1-epimerase, conserved site [IPR018052]", "Alpha-2-macroglobulin, conserved site [IPR019742]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Amyloidogenic glycoprotein,  copper-binding domain conserved site [IPR019744]", "Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]", "Anion exchange, conserved site [IPR018241]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "Arrestin, conserved site [IPR017864]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Band 7/stomatin-like, conserved site [IPR018080]", "Bax inhibitor 1, conserved site [IPR006213]", "Bromodomain, conserved site [IPR018359]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "CBX family C-terminal motif [IPR033773]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific,  conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA mismatch repair, conserved site [IPR014762]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family A, conserved site [IPR019760]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Di-trans-poly-cis-decaprenylcistransferase-like, conserved site [IPR018520]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "Dihydroorotate dehydrogenase, conserved site [IPR001295]", "DnaJ domain, conserved site [IPR018253]", "Dpy-30 motif [IPR007858]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Ephrin, conserved site [IPR019765]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "Fibrillarin, conserved site [IPR020813]", "Folylpolyglutamate synthetase, conserved site [IPR018109]", "Fork head domain conserved site 2 [IPR030456]", "Fork head domain conserved site1 [IPR018122]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glutathione peroxidase conserved site [IPR029760]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 2, conserved site [IPR023230]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "GoLoco motif [IPR003109]", "Golgin subfamily A member 2, C-terminal binding motif [IPR043937]", "Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H4, conserved site [IPR019809]", "Homeobox, conserved site [IPR017970]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "MoaA/NifB/PqqE, iron-sulphur binding, conserved site [IPR000385]", "Molybdenum cofactor biosynthesis, conserved site [IPR008284]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NADH:ubiquinone oxidoreductase, subunit 1, conserved site [IPR018086]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M22, conserved site [IPR017860]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site [IPR023058]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosyl pyrophosphate synthetase, conserved site [IPR000842]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P,  conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S14, conserved site [IPR018271]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "Ribosome-binding factor A, conserved site [IPR020053]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium/solute symporter, conserved site [IPR018212]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Transcription factor, T-box, conserved site [IPR018186]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]", "tRNA-dihydrouridine synthase, conserved site [IPR018517]"], "available_proteins": ["AAAS", "AAMP", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACSS1", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA6", "ANXA7", "AP1M1", "AP2M1", "AP2S1", "AP3M1", "AP3S1", "APEX1", "APP", "ARHGEF7", "ARIH2", "ARRB1", "ARRB2", "ATAD1", "ATAD2", "ATP5C1", "ATP5O", "ATR", "BAG6", "BAK1", "BAZ1A", "BAZ1B", "BAZ2A", "BCR", "BCS1L", "BLM", "BOP1", "BPNT1", "BPTF", "BRCA1", "BRD1", "BRD2", "BRD3", "BRD4", "BUD31", "CAD", "CALR", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CBL", "CBR1", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CDC40", "CDH2", "CDK5RAP1", "CDKAL1", "CETN2", "CHAF1B", "CHD1", "CHD1L", "CHD3", "CHD4", "CLGN", "CMPK1", "CNDP2", "COPA", "COPZ1", "CORO1B", "CORO1C", "CORO7", "CPOX", "CRYZ", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CYP51A1", "DBI", "DCAF13", "DCAF7", "DCP2", "DCPS", "DCXR", "DDT", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX55", "DDX6", "DHCR7", "DHDDS", "DHFR", "DHODH", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIMT1", "DIS3", "DLG1", "DLG3", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC16", "DNAJC2", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DPH7", "DPY30", "DRG1", "DRG2", "DSC3", "DSG2", "DST", "DTL", "DTX3L", "DTYMK", "DUS2", "DYNLL2", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECT2", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EFNB1", "EHHADH", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4E", "EIF4E2", "ENO1", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPRS", "EPS15", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FARP1", "FARP2", "FBL", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FOXC1", "FOXK1", "FPGS", "FUCA1", "FUCA2", "GAA", "GALK1", "GALM", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GLA", "GLB1", "GLB1L2", "GLO1", "GMPPA", "GMPPB", "GMPR2", "GNPDA1", "GNS", "GOLGA2", "GPHN", "GPI", "GPSM1", "GPX8", "GRHPR", "GRWD1", "GSPT1", "GTF3C2", "GUSB", "H4C1*", "HADH", "HADHA", "HADHB", "HGS", "HIBADH", "HLA-A", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMOX1", "HMOX2", "HOXD11", "HSD17B10", "HSD17B12", "HSD17B4", "HSD17B8", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "ILVBL", "IMPDH1", "IMPDH2", "INA", "ING5", "INTS12", "IQGAP1", "IQGAP2", "IQGAP3", "IVD", "KDM2A", "KDM5A", "KDM5B", "KDM5C", "KDSR", "KIF11", "KIF13B", "KIF14", "KIF18B", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "LAMP1", "LARS", "LARS2", "LBR", "LDLR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRP1", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK14", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME1", "ME2", "MGA", "MID1", "MIF", "MOCS1", "MPI", "MPP1", "MPP2", "MPP5", "MPP6", "MPP7", "MPST", "MRPL13", "MRPL3", "MRPS11", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "MVK", "ND1", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS8", "NDUFV1", "NEFL", "NEFM", "NES", "NF1", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NSD1", "NSD2", "NSD3", "NSF", "NUBPL", "NUDT1", "NUDT12", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OSGEP", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PAX6", "PBRM1", "PCK2", "PCNA", "PDE8A", "PDIA3", "PDIA4", "PDIA6", "PEBP1", "PEPD", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHF14", "PHF2", "PHF3", "PHF8", "PHGDH", "PHIP", "PHRF1", "PI4KA", "PIK3C2A", "PIK3C3", "PIN1", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PMS1", "PNP", "PNPLA6", "POLA1", "POLD1", "POLG", "POLR1B", "POLR2B", "POLR2C", "POLR2E", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PRPS1", "PRPS2", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PUS7", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "QDPR", "RACK1", "RAE1", "RANBP2", "RARS", "RARS2", "RBFA", "RCL1", "RDH13", "RDX", "RIDA", "RNF14", "RNF169", "RNF20", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS24", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "RSF1", "RTCA", "RTN4IP1", "S100A11", "SART1", "SBDS", "SCAF11", "SCD", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB1", "SERPINB6", "SERPINH1", "SLC1A5", "SLC25A42", "SLC27A4", "SLC4A2", "SLC5A6", "SLIT2", "SMARCA4", "SMG1", "SMS", "SMU1", "SNRNP40", "SNU13", "SORD", "SPATA5", "SPATA5L1", "SPTBN1", "SPTBN2", "SRCAP", "SRM", "STAM", "STMN1", "STOM", "STRN", "STX12", "STX18", "STX4", "STX5", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SYNE2", "TAF5", "TAP1", "TAP2", "TBL3", "TCP1", "TFB1M", "THOC6", "TK1", "TLN1", "TMBIM6", "TMX1", "TMX3", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRIM21", "TRIM24", "TRIM25", "TRIM28", "TRIM33", "TRIP13", "TRMT11", "TSFM", "TSPAN6", "TST", "TTF2", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUFM", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UBA5", "UHRF1", "UIMC1", "USP10", "USP11", "USP13", "USP14", "USP15", "USP19", "USP24", "USP28", "USP30", "USP32", "USP33", "USP36", "USP38", "USP4", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VARS2", "VAT1", "VCL", "VCP", "VIM", "VPS4A", "VPS4B", "WARS", "WDHD1", "WDR1", "WDR18", "WDR3", "WDR36", "WDR41", "WDR47", "WDR48", "WDR5", "WDR61", "WDR7", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2"], "leading_proteins": ["AKR1B1", "ALDOA", "ATR", "CAPZA2", "CBX1", "CBX8", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CHD1", "CHD3", "COPZ1", "CTBP1", "CUL1", "CUL4B", "CUL5", "DDT", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJC2", "DNAJC9", "DNM2", "DRG2", "ECT2", "EEF1D", "EIF4E", "EPB41L3", "EZR", "FARP1", "FUCA1", "GALK1", "GRHPR", "HMGB3", "IDH2", "MCM2", "MCM3", "MCM4", "MCM5", "MSN", "MTAP", "PFKM", "PFN1", "PGM2", "PHGDH", "PI4KA", "POLD1", "PRPS2", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC3", "PSMC5", "PSMC6", "PYGL", "RPS16", "RPS2", "SMG1", "SORD", "STAM", "TCP1", "TRIP13", "TUBB", "TUBB2B", "TUBB4A", "TUBB6", "UBA5", "VPS4A", "VPS4B", "XPNPEP1", "YWHAB", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ"]}

interpro_domain/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "Proteasome alpha-subunit, N-terminal domain [IPR000426]", "1": "Proteasome component (PCI) domain [IPR000717]", "2": "Importin-beta, N-terminal domain [IPR001494]"}

interpro_domain/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Proteasome alpha-subunit, N-terminal domain [IPR000426]", "1": "Proteasome component (PCI) domain [IPR000717]", "2": "Importin-beta, N-terminal domain [IPR001494]", "3": "Phosphoribosyltransferase domain [IPR000836]", "4": "Phox homology [IPR001683]", "5": "W2 domain [IPR003307]", "6": "14-3-3 domain [IPR023410]", "7": "HECT domain [IPR000569]", "8": "Protein kinase domain [IPR000719]", "9": "Actin-depolymerising factor homology domain [IPR002108]", "10": "CS domain [IPR007052]", "11": "Ubiquitin-associated domain [IPR015940]", "12": "Glutathione S-transferase, C-terminal [IPR004046]", "13": "Clathrin/coatomer adaptor, adaptin-like, N-terminal [IPR002553]", "14": "High mobility group box domain [IPR009071]", "15": "Zinc finger, LIM-type [IPR001781]", "16": "SNF2, N-terminal [IPR000330]", "17": "FERM central domain [IPR019748]", "18": "Band 4.1 domain [IPR019749]", "19": "DnaJ domain [IPR001623]", "20": "Glutathione S-transferase, C-terminal-like [IPR010987]", "21": "SH3 domain [IPR001452]", "22": "Aminoacyl-tRNA synthetase, class Ia [IPR002300]", "23": "Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding [IPR013155]", "24": "Helicase superfamily 1/2, ATP-binding domain [IPR014001]", "25": "Translational (tr)-type GTP-binding domain [IPR000795]", "26": "Cullin homology domain [IPR016158]", "27": "Cullin protein, neddylation domain [IPR019559]", "28": "Dbl homology (DH) domain [IPR000219]", "29": "AAA ATPase, AAA+ lid domain [IPR041569]", "30": "Pleckstrin homology domain [IPR001849]"}