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- interpro_active_site/advanced/idx2term.json +1 -0
- interpro_active_site/basic/idx2term.json +1 -0
- interpro_active_site/basic/plot_0.png +3 -0
- interpro_active_site/consensus.joblib +3 -0
- interpro_active_site/df_merge.tsv +1 -0
- interpro_active_site/metrics.json +7 -0
- interpro_active_site/paths.json +1 -0
- interpro_active_site/result.tsv +2 -0
- interpro_active_site/selections.json +1 -0
- interpro_binding_site/advanced/idx2term.json +1 -0
- interpro_binding_site/basic/idx2term.json +1 -0
- interpro_binding_site/basic/plot_0.png +3 -0
- interpro_binding_site/basic/plot_1.png +3 -0
- interpro_binding_site/consensus.joblib +3 -0
- interpro_binding_site/df_merge.tsv +1 -0
- interpro_binding_site/metrics.json +7 -0
- interpro_binding_site/paths.json +1 -0
- interpro_binding_site/result.tsv +5 -0
- interpro_binding_site/selections.json +1 -0
- interpro_conserved_site/advanced/idx2term.json +1 -0
- interpro_conserved_site/basic/idx2term.json +1 -0
- interpro_conserved_site/basic/plot_0.png +3 -0
- interpro_conserved_site/basic/plot_1.png +3 -0
- interpro_conserved_site/basic/plot_2.png +3 -0
- interpro_conserved_site/consensus.joblib +3 -0
- interpro_conserved_site/df_merge.tsv +1 -0
- interpro_conserved_site/metrics.json +7 -0
- interpro_conserved_site/paths.json +1 -0
- interpro_conserved_site/result.tsv +24 -0
- interpro_conserved_site/selections.json +1 -0
- interpro_domain/advanced/idx2term.json +1 -0
- interpro_domain/advanced/plot_0.png +3 -0
- interpro_domain/basic/idx2term.json +1 -0
- interpro_domain/basic/plot_0.png +3 -0
- interpro_domain/basic/plot_1.png +3 -0
- interpro_domain/basic/plot_10.png +3 -0
- interpro_domain/basic/plot_11.png +3 -0
- interpro_domain/basic/plot_2.png +3 -0
- interpro_domain/basic/plot_3.png +3 -0
- interpro_domain/basic/plot_4.png +3 -0
- interpro_domain/basic/plot_5.png +3 -0
- interpro_domain/basic/plot_6.png +3 -0
- interpro_domain/basic/plot_7.png +3 -0
- interpro_domain/basic/plot_8.png +3 -0
- interpro_domain/basic/plot_9.png +3 -0
- interpro_domain/consensus.joblib +3 -0
- interpro_domain/df_merge.tsv +6 -0
- interpro_domain/metrics.json +7 -0
- interpro_domain/paths.json +1 -0
- interpro_domain/result.tsv +184 -0
interpro_active_site/advanced/idx2term.json
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{}
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interpro_active_site/basic/idx2term.json
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{"0": "Serine/threonine-protein kinase, active site [IPR008271]"}
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interpro_active_site/basic/plot_0.png
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Git LFS Details
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interpro_active_site/consensus.joblib
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oid sha256:a76f37b8a100962d58e13688138b208fdac3c9c3ef17085ebdc41d062e35ae7d
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size 75500
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interpro_active_site/df_merge.tsv
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term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500
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interpro_active_site/metrics.json
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{
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"type_of_task": "ranksum",
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"signature_size": 2734,
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"annotations_size": 55,
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"title": "Average number of proteins per term",
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"value": 2.4
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}
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interpro_active_site/paths.json
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{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C166/C166_val_log2fc"}
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interpro_active_site/result.tsv
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Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
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Serine/threonine-protein kinase, active site [IPR008271] 0.2712346724832289 0.1482245108517688 0.8821655886136517 1.0 0.8985019884027934 39 Q99640,P48729,P11802,P31751,P36507,Q13153,Q13555,Q13546 8
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interpro_active_site/selections.json
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{"all_annotations": ["ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenosine/AMP deaminase active site [IPR006650]", "Adenylosuccinate synthase, active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycoside hydrolase, family 2, active site [IPR023232]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Peptidase family C14A, His active site [IPR016129]", "Peptidase family C14A, cysteine active site [IPR033139]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]", "Uracil-DNA glycosylase, active site [IPR018085]"], "available_proteins": ["ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADA", "ADSS", "AKT2", "APEH", "ATP5A1", "ATP5B", "ATP6V1A", "ATP6V1B2", "AURKA", "BLMH", "BUB1", "CAMK2G", "CAPN1", "CASP3", "CASP6", "CASP7", "CASP8", "CDK1", "CDK12", "CDK2", "CDK4", "CDK6", "CHEK2", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CTSA", "CTSC", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "FASN", "FECH", "G6PD", "GAA", "GANAB", "GAPDH", "GART", "GLUD1", "GSK3A", "GSK3B", "GSR", "GUSB", "HADHB", "HMGCL", "HMGCS1", "LDHA", "LDHB", "LONP1", "MAP2K1", "MAP2K2", "MAP2K3", "MAPK1", "MASTL", "MDH1", "MDH2", "NEK9", "NME1", "NME2", "PAK1", "PAK2", "PASK", "PBK", "PGAM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLK1", "PREP", "PRKACA", "PRPF4B", "PTK7", "PTPN1", "RIPK1", "RNASET2", "ROCK2", "RPS6KA1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SUCLG1", "TALDO1", "TIGAR", "TOP1", "TPI1", "TPP2", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "UMPS", "UNG", "VRK1", "WNK1"], "leading_proteins": ["AKT2", "CAMK2G", "CDK4", "CSNK1A1", "MAP2K2", "PAK1", "PKMYT1", "RIPK1"]}
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interpro_binding_site/advanced/idx2term.json
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{}
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interpro_binding_site/basic/idx2term.json
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{"0": "EF-Hand 1, calcium-binding site [IPR018247]", "1": "Protein kinase, ATP binding site [IPR017441]"}
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interpro_binding_site/basic/plot_0.png
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Git LFS Details
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interpro_binding_site/basic/plot_1.png
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interpro_binding_site/consensus.joblib
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oid sha256:1ed249d56eb47694d77ec8711d5a9e8d0821328958d81d959679b2087e8293da
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size 67969
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interpro_binding_site/df_merge.tsv
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term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500
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interpro_binding_site/metrics.json
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{
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"type_of_task": "ranksum",
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"signature_size": 2734,
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"annotations_size": 31,
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"title": "Average number of proteins per term",
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"value": 4.032258064516129
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}
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interpro_binding_site/paths.json
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{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C166/C166_val_log2fc"}
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interpro_binding_site/result.tsv
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Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
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Peptidase M16, zinc-binding site [IPR001431] 0.6727732219171231 1.1494727683273092 0.2503610893558792 0.9998680480697816 0.3233830737513439 5 O43847,Q10713 2
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EF-Hand 1, calcium-binding site [IPR018247] 0.3736362119161628 1.0946561105677162 0.2736673234461002 0.9999504318092416 0.3393474810731643 36 O95202,O43852,P80303,Q14257,Q9NWM8,Q9BRK5,Q02818,Q9Y680 8
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Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917] 0.4293557833089378 0.6204655753385755 0.5349513113163102 0.999999999950745 0.5718445052001937 2 O75600 1
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Protein kinase, ATP binding site [IPR017441] 0.2687953586682606 0.1191928619149973 0.9051225617019276 1.0 0.9352933137586584 35 Q99640,P48729,P11802,P31751,P36507,Q13153,Q13555 7
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interpro_binding_site/selections.json
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{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "APOBEC/CMP deaminase, zinc-binding [IPR016192]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Adrenodoxin, iron-sulphur binding site [IPR018298]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "AKT2", "APEX1", "AURKA", "BPNT1", "BUB1", "CALM3", "CALU", "CAMK2G", "CAPN1", "CAPNS1", "CDK1", "CDK12", "CDK2", "CDK4", "CDK6", "CETN2", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A2", "CYB5B", "DCTD", "DLAT", "DLST", "DST", "EHD1", "EHD4", "EIF2AK2", "EPS15", "EPS15L1", "FDX1", "FKBP10", "FKBP14", "FKBP7", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3A", "GSK3B", "HK1", "HK2", "HMBS", "IDE", "ILKAP", "IQGAP1", "LETM1", "MACF1", "MAP2K1", "MAP2K2", "MAP2K3", "MAPK1", "MAPK14", "MCCC1", "MICU1", "MYH10", "MYH14", "MYH9", "MYO1B", "MYO1D", "NFS1", "NRDC", "NUCB1", "NUCB2", "PA2G4", "PAK1", "PAK2", "PASK", "PC", "PCCA", "PDCD6", "PEF1", "PGD", "PKMYT1", "PKN1", "PKN2", "PLCG1", "PLK1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1G", "PRKACA", "PRKCSH", "PSAT1", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "ROCK2", "RPS6KA1", "RPS6KA3", "S100A11", "SDF4", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "STK4", "TKT", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "UQCRC2", "VRK1"], "leading_proteins": ["AKT2", "CALU", "CAMK2G", "CDK4", "CSNK1A1", "FKBP14", "FKBP7", "GCAT", "LETM1", "MAP2K2", "NRDC", "NUCB1", "NUCB2", "PAK1", "PKMYT1", "PMPCA", "RCN2", "SDF4"]}
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interpro_conserved_site/advanced/idx2term.json
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{}
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interpro_conserved_site/basic/idx2term.json
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{"0": "Intermediate filament protein, conserved site [IPR018039]", "1": "Zinc finger, RING-type, conserved site [IPR017907]", "2": "Mini-chromosome maintenance, conserved site [IPR018525]"}
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interpro_conserved_site/basic/plot_0.png
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Git LFS Details
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interpro_conserved_site/basic/plot_1.png
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interpro_conserved_site/basic/plot_2.png
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interpro_conserved_site/consensus.joblib
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version https://git-lfs.github.com/spec/v1
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oid sha256:0d46bd0db0da8d5b0552250c9827e065ff2e75f007e7d0060574f5e47f049817
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size 123390
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interpro_conserved_site/df_merge.tsv
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term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500
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interpro_conserved_site/metrics.json
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{
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"type_of_task": "ranksum",
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"signature_size": 2734,
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"annotations_size": 264,
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"title": "Average number of proteins per term",
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"value": 2.496212121212121
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}
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interpro_conserved_site/paths.json
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{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C166/C166_val_log2fc"}
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interpro_conserved_site/result.tsv
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Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
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Haem oxygenase conserved site [IPR018207] 0.9344802342606168 3.1344566453683047 0.0017217269368705 0.3655061308784072 0.007102123614591 2 P30519 1
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Tetraspanin, conserved site [IPR018503] 0.9213030746705726 3.075395732778736 0.002102234182352 0.4262571630440162 0.0082834302110586 2 O60637 1
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Sterol reductase, conserved site [IPR018083] 0.91617862371889 3.052315331275125 0.0022708340994908 0.4512881931307207 0.0085642886037938 2 Q14739 1
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3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180] 0.8744509516837496 2.861994325338233 0.0042098444434641 0.6716729054020447 0.0126295333303925 2 Q16836 1
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Glycoside hydrolase, family 29, conserved site [IPR018526] 0.7902635431918014 2.464707866294726 0.0137125000276316 0.9738824970012928 0.0325041304678697 2 Q9BTY2 1
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Dynamin, GTPase region, conserved site [IPR019762] 0.7895314787701322 2.4611735345235535 0.0138483365831767 0.9748151211401868 0.0325041304678697 2 P50570 1
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| 8 |
+
Sugar transporter, conserved site [IPR005829] 0.7877013177159644 2.4523316546789267 0.0141933775588873 0.9770376109754716 0.0325830580482284 2 P11166 1
|
| 9 |
+
Guanylate kinase, conserved site [IPR020590] 0.8824175824175827 2.036968221707832 0.0416532266481579 0.999986756925211 0.0723450778625901 4 O14936,Q9NZW5,Q14168 3
|
| 10 |
+
Intermediate filament protein, conserved site [IPR018039] 0.7558698621372664 1.8674818765152923 0.0618343253969935 0.9999999519383912 0.0954274953935921 8 Q16352,P07196,P48681,P07197,P08670 5
|
| 11 |
+
Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364] 0.8403592287619716 1.8650638200873444 0.0621724591200676 0.9999999563014176 0.0954274953935921 4 Q8N4Q0,Q8WWV3 2
|
| 12 |
+
Mitogen-activated protein (MAP) kinase, conserved site [IPR003527] 0.650805270863837 1.767149974070075 0.077203115090187 0.999999999386216 0.1107696868685292 2 P28482 1
|
| 13 |
+
Syntaxin/epimorphin, conserved site [IPR006012] 0.8150183150183157 1.7602126210195197 0.0783717628469282 0.9999999995607376 0.1118386237383192 4 Q9P2W9,O15400,Q13190 3
|
| 14 |
+
IMP dehydrogenase / GMP reductase, conserved site [IPR015875] 0.637628111273795 1.6989239879322937 0.0893335065886797 0.9999999999813418 0.1242481013501381 2 P20839 1
|
| 15 |
+
Proteasome beta-type subunit, conserved site [IPR016050] 0.7166008400392367 1.682614586666947 0.0924497260690775 0.9999999999924516 0.1271183733449816 8 Q99436,P28070,P28072,P49721 4
|
| 16 |
+
Mrp, conserved site [IPR000808] 0.5527086383601807 1.253284082974449 0.2101023389981524 1.0 0.2616368749788313 2 Q9Y5Y2 1
|
| 17 |
+
GTP1/OBG, conserved site [IPR006074] 0.5223279648609146 1.0932141441783785 0.274299788293709 1.0 0.3337103415186137 2 Q9Y295 1
|
| 18 |
+
Histidine triad, conserved site [IPR019808] 0.5197657393850657 1.0797591008800076 0.2802494681963385 1.0 0.3378349753599697 2 Q9BX68 1
|
| 19 |
+
Oxysterol-binding protein, conserved site [IPR018494] 0.6416312435260497 1.0167422581624548 0.309276057200115 1.0 0.3694519416327165 5 Q9BZF3 1
|
| 20 |
+
ABC transporter-like, conserved site [IPR017871] 0.5449778691646638 0.7818028871852637 0.4343304240181598 1.0 0.4921168752823784 7 P08183,O75027 2
|
| 21 |
+
AMP-binding, conserved site [IPR020845] 0.4831011642729539 0.3989544296971501 0.6899267823454094 1.0 0.7464781579474922 4 O60488 1
|
| 22 |
+
Zinc finger, RING-type, conserved site [IPR017907] 0.3587013881993146 0.2471350192129269 0.8048037326963347 1.0 0.8397951993353057 12 O75150,P14373,O15164,Q14527,Q9UBS8,Q9UPQ4,Q9UPN9,P19474,Q5VTR2,Q96T88 10
|
| 23 |
+
Enoyl-CoA hydratase/isomerase, conserved site [IPR018376] 0.4107866498708949 0.1636456911241944 0.8700100732221292 1.0 0.8868056344812436 5 Q13011 1
|
| 24 |
+
Mini-chromosome maintenance, conserved site [IPR018525] 0.3907624633431089 0.1482615861781141 0.8821363300490748 1.0 0.8957076582036759 6 P49736,Q14566,P25205,P33993,P33992 5
|
interpro_conserved_site/selections.json
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{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Amyloidogenic glycoprotein, copper-binding domain conserved site [IPR019744]", "Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Band 7/stomatin-like, conserved site [IPR018080]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "CBX family C-terminal motif [IPR033773]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific, conserved site [IPR031303]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "Fibrillarin, conserved site [IPR020813]", "Fork head domain conserved site 2 [IPR030456]", "Fork head domain conserved site1 [IPR018122]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glutathione peroxidase conserved site [IPR029760]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 2, conserved site [IPR023230]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Helix-turn-helix motif [IPR000047]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "Homeobox, conserved site [IPR017970]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "Molybdenum cofactor biosynthesis, conserved site [IPR008284]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M22, conserved site [IPR017860]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site [IPR023058]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosyl pyrophosphate synthetase, conserved site [IPR000842]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Rel homology domain, conserved site [IPR030492]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P, conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Transcription factor TFIIB, conserved site [IPR023486]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]"], "available_proteins": ["AAAS", "ABCB1", "ABCB10", "ABCB7", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ACAA2", "ACAD9", "ACADM", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACSL1", "ACSL3", "ACSL4", "ACTN1", "ACTN2", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK4", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA6", "ANXA7", "AP1M1", "AP2M1", "AP2S1", "AP3M1", "APEX1", "APP", "ATAD1", "ATP5C1", "ATP5O", "BAG6", "BAK1", "BAZ1A", "BAZ1B", "BCS1L", "BDH2", "BOP1", "BPNT1", "BPTF", "BRD4", "BUD31", "CAD", "CALR", "CANX", "CAP1", "CAPZA1", "CAPZB", "CASK", "CBR1", "CBX1", "CBX3", "CBX5", "CBX8", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDC40", "CDX2", "CETN2", "CHAF1B", "CHD1", "CHD4", "CLGN", "CMPK1", "CNDP2", "COLEC12", "COPA", "COPZ1", "CORO1B", "CORO1C", "CPOX", "CRYZ", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CYP51A1", "DCAF13", "DCAF7", "DCPS", "DCXR", "DDT", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX55", "DDX6", "DHCR7", "DHFR", "DHRS7B", "DHX15", "DHX16", "DHX30", "DHX36", "DHX38", "DHX8", "DHX9", "DIDO1", "DIS3", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC2", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DRG1", "DRG2", "DSG2", "DST", "DTL", "DTYMK", "DYNLL1", "DYNLL2", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4E", "ENO1", "EPB41", "EPB41L2", "EPB41L3", "EPRS", "EPS15", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FBL", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FOXC1", "FUCA1", "FUCA2", "GAA", "GALK1", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GLA", "GLB1", "GLO1", "GMPPA", "GMPPB", "GNPDA1", "GNS", "GPHN", "GPI", "GPX8", "GRHPR", "GRWD1", "GSPT1", "GTF2B", "GTF3C2", "GUSB", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HGS", "HIBADH", "HINT2", "HLA-A", "HLA-B", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMOX1", "HMOX2", "HSD17B10", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "ILVBL", "IMPDH1", "IMPDH2", "INA", "IQGAP1", "IVD", "KDM2A", "KDSR", "KIF11", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "LAMP1", "LAMP2", "LARS", "LARS2", "LBR", "LDLR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LSS", "MACF1", "MAPK1", "MAPK14", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME2", "MGST2", "MID1", "MIF", "MPI", "MPP1", "MPP2", "MPP6", "MPST", "MRC2", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS8", "NDUFV1", "NEFL", "NEFM", "NES", "NFKB1", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NSD2", "NSF", "NUBP2", "NUBPL", "NUDT1", "NUDT5", "NUP153", "NUP37", "NVL", "OSBP", "OSBPL11", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PBRM1", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA6", "PEBP1", "PEPD", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PHF8", "PHGDH", "PI4KB", "PIK3C3", "PIN1", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS3", "PNP", "POLA1", "POLD1", "POLR1B", "POLR1C", "POLR2B", "POLR2C", "POLR2E", "PPIB", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PRPS2", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PUS7", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "QDPR", "RACK1", "RAE1", "RANBP2", "RARS", "RARS2", "RCL1", "RDH13", "RDX", "RIDA", "RNF14", "RNF20", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS24", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RSF1", "RTN4IP1", "S100A10", "S100A11", "SART1", "SBDS", "SCD", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB6", "SERPINH1", "SLC1A5", "SLC27A4", "SLC2A1", "SLIT2", "SMARCA4", "SMU1", "SNRNP40", "SNU13", "SORD", "SPATA5L1", "SPTBN1", "SPTBN2", "SRM", "STAM", "STMN1", "STOM", "STRN", "STX12", "STX18", "STX5", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SV2A", "SYNE2", "TBL3", "TCP1", "THOC6", "TK1", "TLN1", "TMX1", "TMX3", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRIM21", "TRIM24", "TRIM25", "TRIM27", "TRIM28", "TRIM33", "TRIM35", "TRIP13", "TSFM", "TSPAN3", "TSPAN6", "TTF2", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUFM", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UBFD1", "UHRF1", "USP10", "USP11", "USP14", "USP15", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VARS2", "VAT1", "VCL", "VCP", "VIM", "VPS4B", "WARS", "WDHD1", "WDR1", "WDR18", "WDR3", "WDR36", "WDR41", "WDR5", "WDR61", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2"], "leading_proteins": ["ABCB1", "ABCB7", "ACSL4", "CASK", "DNM2", "DRG1", "ECH1", "FUCA2", "HADH", "HINT2", "HLTF", "HMOX2", "IMPDH1", "INA", "LBR", "MAPK1", "MCM2", "MCM3", "MCM5", "MCM6", "MCM7", "MPP2", "MPP6", "NEFL", "NEFM", "NES", "NUBP2", "OSBPL6", "PSMB2", "PSMB4", "PSMB6", "PSMB7", "RNF14", "RNF20", "RNF40", "RTN4IP1", "SLC2A1", "STX18", "STX5", "STX7", "TRIM21", "TRIM24", "TRIM27", "TRIM33", "TRIM35", "TSPAN3", "UHRF1", "VIM", "ZADH2"]}
|
interpro_domain/advanced/idx2term.json
ADDED
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@@ -0,0 +1 @@
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| 1 |
+
{"0": "RNA recognition motif domain [IPR000504]"}
|
interpro_domain/advanced/plot_0.png
ADDED
|
Git LFS Details
|
interpro_domain/basic/idx2term.json
ADDED
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| 1 |
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{"0": "RNA recognition motif domain [IPR000504]", "1": "Intermediate filament, rod domain [IPR039008]", "2": "K Homology domain, type 1 [IPR004088]", "3": "K Homology domain [IPR004087]", "4": "EF-hand domain [IPR002048]", "5": "MCM N-terminal domain [IPR027925]", "6": "MCM domain [IPR001208]", "7": "MCM, AAA-lid domain [IPR041562]", "8": "MCM OB domain [IPR033762]", "9": "Protein kinase domain [IPR000719]", "10": "DnaJ domain [IPR001623]", "11": "Zinc finger, RING-type [IPR001841]"}
|
interpro_domain/basic/plot_0.png
ADDED
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Git LFS Details
|
interpro_domain/basic/plot_1.png
ADDED
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Git LFS Details
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interpro_domain/basic/plot_10.png
ADDED
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Git LFS Details
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interpro_domain/basic/plot_11.png
ADDED
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Git LFS Details
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interpro_domain/basic/plot_2.png
ADDED
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Git LFS Details
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interpro_domain/basic/plot_3.png
ADDED
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Git LFS Details
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interpro_domain/basic/plot_4.png
ADDED
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Git LFS Details
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interpro_domain/basic/plot_5.png
ADDED
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Git LFS Details
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interpro_domain/basic/plot_6.png
ADDED
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Git LFS Details
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interpro_domain/basic/plot_7.png
ADDED
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Git LFS Details
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interpro_domain/basic/plot_8.png
ADDED
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Git LFS Details
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interpro_domain/basic/plot_9.png
ADDED
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Git LFS Details
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interpro_domain/consensus.joblib
ADDED
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| 1 |
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version https://git-lfs.github.com/spec/v1
|
| 2 |
+
oid sha256:746413ad65d56d76217402f6bbb3c1ef39d83504a106bf3b7d73ae84d3533c19
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| 3 |
+
size 702546
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interpro_domain/df_merge.tsv
ADDED
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| 1 |
+
term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500
|
| 2 |
+
RNA recognition motif domain [IPR000504] 47 115 2.9070156649615795 0.0036489492412328 39.713592233009706 116.0 0.2316956716939257 0.5316884276370477 13.873754985119357 5.729331786381952 1.713447249572458 0.3950212299678106 0.0013045100247433 1.0 0.8195646169006738 1.0199156994074962e-06 4.376670445801541e-13
|
| 3 |
+
Aminopeptidase N-like , N-terminal domain [IPR045357] 2 5 1.982702643867416 0.0474006541036418 2.121359223300971 5.466019417475728 1.4317001483019938 0.1783942022754649 1.021530403905949 0.5881604361499402 0.986353205880356 0.2226891741813114 0.0003127091156062 0.0006219606051344 0.0025156479029566 0.0007187465088185 0.0053637976870067
|
| 4 |
+
Peptidase M1, membrane alanine aminopeptidase [IPR014782] 2 5 1.982702643867416 0.0474006541036418 2.121359223300971 5.466019417475728 1.4317001483019938 0.1783942022754649 1.021530403905949 0.5881604361499402 0.986353205880356 0.2226891741813114 0.0003127091156062 0.0006219606051344 0.0025156479029566 0.0007187465088185 0.0053637976870067
|
| 5 |
+
Guanylate kinase/L-type calcium channel beta subunit [IPR008145] 3 5 1.978061186580195 0.0479218045014471 2.9975728155339807 6.963592233009709 0.5006632403339694 0.4738825144563896 2.043814711463587 1.6869386038453082 0.907662015536667 0.3076020117251588 0.041818515662187 1.0 1.0 0.0693365470158766 0.0098879726868235
|
| 6 |
+
Guanylate kinase-like domain [IPR008144] 3 5 1.978061186580195 0.0479218045014471 2.9975728155339807 6.963592233009709 0.5006632403339694 0.4738825144563896 2.043814711463587 1.6869386038453082 0.907662015536667 0.3076020117251588 0.0297379856574316 1.0 1.0 0.0498779046475234 0.0049531384619904
|
interpro_domain/metrics.json
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+
{
|
| 2 |
+
"type_of_task": "ranksum",
|
| 3 |
+
"signature_size": 2734,
|
| 4 |
+
"annotations_size": 2335,
|
| 5 |
+
"title": "Average number of proteins per term",
|
| 6 |
+
"value": 2.091648822269807
|
| 7 |
+
}
|
interpro_domain/paths.json
ADDED
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| 1 |
+
{"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C166/C166_val_log2fc"}
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interpro_domain/result.tsv
ADDED
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| 1 |
+
Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
|
| 2 |
+
Metaxin, glutathione S-transferase domain [IPR033468] 0.9795021961932656 3.3331720487736956 0.0008586182917225 0.8654386317915143 0.0034096491686599 2 Q13505 1
|
| 3 |
+
Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain [IPR019564] 0.9795021961932656 3.3331720487736956 0.0008586182917225 0.8654386317915143 0.0034096491686599 2 Q13505 1
|
| 4 |
+
EXPERA domain [IPR033118] 0.9619326500732072 3.256183517322716 0.001129207397039 0.9285093840886168 0.0042322620739745 2 Q15125 1
|
| 5 |
+
Endoplasmic reticulum vesicle transporter, C-terminal [IPR012936] 0.9553440702781858 3.227129615766365 0.0012503880519882 0.946146235785342 0.0045126060299732 2 Q9Y282 1
|
| 6 |
+
Endoplasmic reticulum vesicle transporter, N-terminal [IPR039542] 0.9553440702781858 3.227129615766365 0.0012503880519882 0.946146235785342 0.0045126060299732 2 Q9Y282 1
|
| 7 |
+
Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337] 0.9447291361639828 3.180107967640672 0.0014722018933504 0.9679393007553626 0.005130733464139 2 O60506 1
|
| 8 |
+
Acyl-CoA oxidase, C-terminal [IPR002655] 0.9399707174231352 3.15894353998777 0.0015834216270593 0.9752819065929296 0.0053817896640227 2 O15254 1
|
| 9 |
+
Sam68, tyrosine-rich domain [IPR032335] 0.9143484626647144 3.044057003678251 0.0023341090882487 0.9957315958295236 0.0072209487285474 2 O75525 1
|
| 10 |
+
KHDRBS, Qua1 domain [IPR032571] 0.9143484626647144 3.044057003678251 0.0023341090882487 0.9957315958295236 0.0072209487285474 2 O75525 1
|
| 11 |
+
Complex 1 LYR protein domain [IPR008011] 0.899341142020498 2.9760325195757904 0.0029200389615993 0.9989172652197458 0.0083969100681458 2 Q9NU23 1
|
| 12 |
+
Potentiating neddylation domain [IPR005176] 0.8920204978038082 2.9426504424856192 0.003254156293456 0.9995049466939508 0.0091437484298674 2 Q92564 1
|
| 13 |
+
CARG-binding factor, N-terminal [IPR012956] 0.8894582723279678 2.930935617176559 0.0033794281258985 0.9996308576677256 0.0093494842108685 2 Q99729 1
|
| 14 |
+
RNA recognition motif domain [IPR000504] 0.430414565964125 2.9070156649615795 0.0036489492412328 0.9998037025529648 0.0097934442279064 115 Q12849,P52272,O60506,Q9Y6M1,P98175,Q01844,O43390,Q9BQ04,Q9UHX1,Q9P2K5,P23246,P84103,Q99729,P35637,P08621,P52597,P23588,P14866,Q14103,Q13151,P55795,P09651,P62995,Q96PK6,Q96EP5,P22626,P51991,P38159,Q92804,P31942,Q9BWF3,O43347,Q9P2N5,Q93062,O14979,Q13242,Q07955,Q01085,P31943,Q15287,P98179,P43243,P07910,Q8IY67,Q13595,Q15233,P31483 47
|
| 15 |
+
Far upstream element-binding protein, C-terminal [IPR015096] 0.8832357247437773 2.9024179137743404 0.0037029418939007 0.999827034335276 0.0098853496153544 2 Q92945 1
|
| 16 |
+
3-hydroxyacyl-CoA dehydrogenase, C-terminal [IPR006108] 0.8744509516837496 2.861994325338233 0.0042098444434641 0.9999472916351214 0.0108021832697679 2 Q16836 1
|
| 17 |
+
3-hydroxyacyl-CoA dehydrogenase, NAD binding [IPR006176] 0.8744509516837496 2.861994325338233 0.0042098444434641 0.9999472916351214 0.0108021832697679 2 Q16836 1
|
| 18 |
+
GMP phosphodiesterase, delta subunit [IPR008015] 0.9835225192237278 2.8576574323671364 0.0042678086510765 0.9999539903299784 0.0109388948411238 3 A6NIH7,O43924 2
|
| 19 |
+
ATPase family AAA domain-containing protein 3, N-terminal [IPR021911] 0.870058565153736 2.841710500903071 0.0044872217932263 0.9999724977089668 0.0114135761298295 2 Q5T9A4 1
|
| 20 |
+
Phospholipase D/Transphosphatidylase [IPR001736] 0.8612737920937056 2.8009980608944978 0.0050944825149417 0.9999933840091598 0.0125085348815866 2 Q8IV08 1
|
| 21 |
+
Fatty acid hydroxylase [IPR006694] 0.8539531478770164 2.76692289565357 0.0056588137213089 0.9999982411626558 0.0135928910019262 2 Q15800 1
|
| 22 |
+
Marvel domain [IPR008253] 0.833455344070283 2.6707908055931906 0.0075672791277012 0.9999999801843013 0.0169978648041804 2 O43760 1
|
| 23 |
+
TRAM/LAG1/CLN8 homology domain [IPR006634] 0.9362870743317464 2.6613422455403235 0.0077829802252118 0.9999999880716628 0.0173574582864084 3 Q96G23,P27544 2
|
| 24 |
+
Zinc finger, CHHC-type [IPR012996] 0.9340900768949104 2.6521015593358936 0.0079992477094867 0.999999992829928 0.0178227513374538 3 P31943,P52597 2
|
| 25 |
+
ERAP1-like C-terminal domain [IPR024571] 0.925031226170825 2.6138955797568753 0.0089516390333792 0.999999999238852 0.0195529252974186 3 P55786 1
|
| 26 |
+
Syntaxin, N-terminal domain [IPR006011] 0.8144216691068805 2.580565587372103 0.0098638617388593 0.9999999999113622 0.0212082110131091 2 O15400 1
|
| 27 |
+
Gamma tubulin complex component protein, N-terminal [IPR041470] 0.8111273792093757 2.564855321067748 0.0103218834425529 0.9999999999699106 0.02189064290496 2 Q9BSJ2 1
|
| 28 |
+
Gamma tubulin complex component, C-terminal [IPR040457] 0.8111273792093757 2.564855321067748 0.0103218834425529 0.9999999999699106 0.02189064290496 2 Q9BSJ2 1
|
| 29 |
+
RBM4, RNA recognition motif 2 [IPR034898] 0.8023426061493475 2.522824728788913 0.0116416409247688 0.9999999999986658 0.0240664699247148 2 Q9BWF3 1
|
| 30 |
+
RBM4, RNA recognition motif 1 [IPR034897] 0.8023426061493475 2.522824728788913 0.0116416409247688 0.9999999999986658 0.0240664699247148 2 Q9BWF3 1
|
| 31 |
+
L27 domain, C-terminal [IPR014775] 0.9025997803002564 2.5185671380792853 0.0117833416712702 0.9999999999990454 0.0242415002664458 3 O14936,Q14168 2
|
| 32 |
+
L27 domain [IPR004172] 0.9025997803002564 2.5185671380792853 0.0117833416712702 0.9999999999990454 0.0242415002664458 3 O14936,Q14168 2
|
| 33 |
+
Zinc finger C2H2 AKAP95-type [IPR034736] 0.8945441230318565 2.4840801381691984 0.0129886574424598 0.9999999999999448 0.0262130640692684 3 Q5BKZ1,Q9ULX6 2
|
| 34 |
+
Alpha-L-fucosidase, C-terminal [IPR031919] 0.7902635431918014 2.464707866294726 0.0137125000276316 0.99999999999999 0.0271973344049297 2 Q9BTY2 1
|
| 35 |
+
Dynamin stalk domain [IPR000375] 0.7895314787701322 2.4611735345235535 0.0138483365831767 0.9999999999999928 0.0273337835348416 2 P50570 1
|
| 36 |
+
Dynamin GTPase effector [IPR003130] 0.7895314787701322 2.4611735345235535 0.0138483365831767 0.9999999999999928 0.0273337835348416 2 P50570 1
|
| 37 |
+
GTPase effector domain [IPR020850] 0.7895314787701322 2.4611735345235535 0.0138483365831767 0.9999999999999928 0.0273337835348416 2 P50570 1
|
| 38 |
+
CTP synthase, N-terminal [IPR017456] 0.7818448023426086 2.4239795568488174 0.0153514696385212 0.9999999999999998 0.0295026186057178 2 P17812 1
|
| 39 |
+
CTP synthase GATase domain [IPR033828] 0.7818448023426086 2.4239795568488174 0.0153514696385212 0.9999999999999998 0.0295026186057178 2 P17812 1
|
| 40 |
+
Damage-control phosphatase ARMT1-like, metal-binding domain [IPR002791] 0.7730600292825749 2.38128552211654 0.0172523340036638 1.0 0.0325134785299073 2 Q9H993 1
|
| 41 |
+
Glycosyltransferase 2-like [IPR001173] 0.7591508052708605 2.3132802006733013 0.0207072385466622 1.0 0.03739474246439 2 Q86SF2 1
|
| 42 |
+
N-acetylgalactosaminyltransferase [IPR045885] 0.7591508052708605 2.3132802006733013 0.0207072385466622 1.0 0.03739474246439 2 Q86SF2 1
|
| 43 |
+
Reticulon [IPR003388] 0.8502153546504938 2.2919132311106103 0.0219106506151001 1.0 0.0392041143189722 3 Q9NQC3 1
|
| 44 |
+
Zinc finger, B-box, chordata [IPR020457] 0.7445095168374901 2.2411597604306324 0.0250157283402874 1.0 0.0435258760615284 2 P14373 1
|
| 45 |
+
Tim44-like domain [IPR007379] 0.741215226939977 2.224857343123779 0.0260908164184465 1.0 0.0450940461414306 2 O43615 1
|
| 46 |
+
Peptidase M28 [IPR007484] 0.833419639130099 2.2180494362369982 0.0265514618683675 1.0 0.0457547331827588 3 Q7Z2K6 1
|
| 47 |
+
Rhodanese-like domain [IPR001763] 0.7320644216691127 2.1794286514299968 0.0292998396175208 1.0 0.0495044323494291 2 Q99956 1
|
| 48 |
+
Potassium channel tetramerisation-type BTB domain [IPR003131] 0.7280380673499343 2.1593731870225787 0.030821226347653 1.0 0.0515526959324999 2 Q9NXV2 1
|
| 49 |
+
GRAM domain [IPR004182] 0.7218155197657405 2.128298588683109 0.0333123350539374 1.0 0.0547776777119324 2 Q66K14 1
|
| 50 |
+
p21 activated kinase binding domain [IPR033923] 0.7119326500732116 2.0787473694786316 0.0376405766140859 1.0 0.0604891578760431 2 Q13153 1
|
| 51 |
+
CRIB domain [IPR000095] 0.7119326500732116 2.0787473694786316 0.0376405766140859 1.0 0.0604891578760431 2 Q13153 1
|
| 52 |
+
Peptidase M41 [IPR000642] 0.7112005856515367 2.07506734646775 0.0379802935448947 1.0 0.0608675260311113 2 Q96TA2 1
|
| 53 |
+
Dynamin, GTPase domain [IPR001401] 0.7898205785426584 2.0236588312045947 0.0430052672692338 1.0 0.0667224578562531 3 P50570,O60313 2
|
| 54 |
+
FAD dependent oxidoreductase [IPR006076] 0.7885929451742528 2.018131060514351 0.0435776135910166 1.0 0.067520721788337 3 P43304 1
|
| 55 |
+
Aminopeptidase N-like , N-terminal domain [IPR045357] 0.8708154093864938 1.982702643867416 0.0474006541036418 1.0 0.0718549458624527 5 P09960,P55786 2
|
| 56 |
+
Peptidase M1, membrane alanine aminopeptidase [IPR014782] 0.8708154093864938 1.982702643867416 0.0474006541036418 1.0 0.0718549458624527 5 P09960,P55786 2
|
| 57 |
+
Guanylate kinase/L-type calcium channel beta subunit [IPR008145] 0.8696789574575212 1.978061186580195 0.0479218045014471 1.0 0.072331876865468 5 O14936,Q9NZW5,Q14168 3
|
| 58 |
+
Guanylate kinase-like domain [IPR008144] 0.8696789574575212 1.978061186580195 0.0479218045014471 1.0 0.072331876865468 5 O14936,Q9NZW5,Q14168 3
|
| 59 |
+
Major facilitator superfamily domain [IPR020846] 0.7781032588795312 1.9707803550152336 0.0487490046800247 1.0 0.073201881625632 3 P11166,Q7L0J3 2
|
| 60 |
+
Peptidase S9A, N-terminal domain [IPR023302] 0.6855783308931214 1.9454534854335976 0.0517204228234053 1.0 0.0761938090174458 2 P48147 1
|
| 61 |
+
PABP, RNA recognition motif 2 [IPR045305] 0.6844802342606151 1.939863974417845 0.0523962232972206 1.0 0.0769950795462618 2 Q13310 1
|
| 62 |
+
Cation-transporting P-type ATPase, N-terminal [IPR004014] 0.7701146404107877 1.9345797575686705 0.0530418860253278 1.0 0.0776506607330035 3 P16615 1
|
| 63 |
+
Cation-transporting P-type ATPase, C-terminal [IPR006068] 0.7701146404107877 1.9345797575686705 0.0530418860253278 1.0 0.0776506607330035 3 P16615 1
|
| 64 |
+
Intermediate filament head, DNA-binding domain [IPR006821] 0.8549450549450553 1.924988876688652 0.0542307498373388 1.0 0.079192495853775 4 Q16352,P07197,P08670 3
|
| 65 |
+
Peptidyl-prolyl cis-trans isomerase, PpiC-type [IPR000297] 0.6800878477306036 1.9174782118489369 0.0551772063980271 1.0 0.0802233978452013 2 Q13526 1
|
| 66 |
+
Fibronectin type II domain [IPR000562] 0.7617041721048783 1.8963395176793665 0.0579151639631954 1.0 0.0836313592171065 3 Q9UBG0 1
|
| 67 |
+
Intermediate filament, rod domain [IPR039008] 0.7558698621372664 1.8674818765152923 0.0618343253969935 1.0 0.0883617807845654 8 Q16352,P07196,P48681,P07197,P08670 5
|
| 68 |
+
Class II aldolase/adducin N-terminal [IPR001303] 0.6676427525622284 1.8538154971582328 0.0637655605886826 1.0 0.0901832731523767 2 P35611 1
|
| 69 |
+
EB1, C-terminal [IPR004953] 0.6647144948755506 1.8387863963260735 0.0659466099110703 1.0 0.0925949092858384 2 Q15691 1
|
| 70 |
+
Glycogen synthase kinase 3, catalytic domain [IPR039192] 0.6625183016105468 1.8275024378965607 0.0676242599907277 1.0 0.0942139899035496 2 P49840 1
|
| 71 |
+
Cytochrome b5-like heme/steroid binding domain [IPR001199] 0.7889503612266272 1.8035009633005143 0.0713095742925618 1.0 0.0979408517096915 6 Q8WUJ1,O15173,O43169 3
|
| 72 |
+
PI31 proteasome regulator, N-terminal [IPR021625] 0.6537335285505144 1.7822646814247387 0.074706079346221 1.0 0.1021303836495469 2 Q9Y3I1 1
|
| 73 |
+
Alcohol dehydrogenase, N-terminal [IPR013154] 0.7823246626505828 1.7745113592799493 0.0759786048406478 1.0 0.1036273611582434 6 Q8N4Q0,Q8WWV3 2
|
| 74 |
+
NOPS [IPR012975] 0.7341633101428051 1.7702362656647384 0.0766877903147174 1.0 0.1042293308410157 3 P23246,Q15233 2
|
| 75 |
+
P-type ATPase, haloacid dehalogenase domain [IPR044492] 0.8122437610377673 1.7486779738223428 0.0803466994978006 1.0 0.1080457885770217 4 Q9HD20 1
|
| 76 |
+
Polyketide synthase, enoylreductase domain [IPR020843] 0.7520115784342254 1.741142833689182 0.0816585447763209 1.0 0.1095190706793276 7 Q8N4Q0,Q8WWV3 2
|
| 77 |
+
26S proteasome regulatory subunit Rpn7, N-terminal [IPR045135] 0.6456808199121546 1.7406578022660903 0.0817435791343914 1.0 0.1095701821347899 2 Q15008 1
|
| 78 |
+
Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862] 0.7240327415225716 1.7235288263198851 0.0847929369106046 1.0 0.1126600716818723 3 Q32P28 1
|
| 79 |
+
IMP dehydrogenase/GMP reductase [IPR001093] 0.637628111273795 1.6989239879322937 0.0893335065886797 1.0 0.1179161887419826 2 P20839 1
|
| 80 |
+
Peptidase M3A/M3B catalytic domain [IPR001567] 0.715488831929696 1.6840112267177387 0.0921794990835893 1.0 0.1213298367306545 3 Q9BYT8,Q99797 2
|
| 81 |
+
BAT2, N-terminal [IPR009738] 0.6317715959004424 1.668496072164386 0.0952172910064252 1.0 0.1249760396290067 2 P48634 1
|
| 82 |
+
Heterogeneous nuclear ribonucleoprotein U, SPRY domain [IPR035778] 0.7105180448333246 1.6609696001861962 0.0967195523324346 1.0 0.1262345894849891 3 Q1KMD3 1
|
| 83 |
+
MoaB/Mog domain [IPR001453] 0.62188872620791 1.6170122244966658 0.1058756421838118 1.0 0.1359096341391977 2 Q8NFF5 1
|
| 84 |
+
K Homology domain, type 1 [IPR004088] 0.490149451212525 1.5670880049453924 0.117094122550603 1.0 0.1466030971344011 21 Q96AE4,O75525,O00425,Q9Y6M1,Q07666,Q06787,Q96I24,Q9NQT5,Q15637,P61978,Q92945,Q8TCS8 12
|
| 85 |
+
Ubiquitin-like domain, USP-type [IPR028135] 0.6105417276720395 1.5577062015197516 0.1193029097485711 1.0 0.1488895212522253 2 P51784 1
|
| 86 |
+
K Homology domain [IPR004087] 0.4877496611648977 1.5493149595777054 0.121306025347883 1.0 0.1506646644613334 21 O75525,Q07666,Q96I24,P61978,Q92945 5
|
| 87 |
+
Fragile X-related 1 protein, C-terminal region 1 [IPR032172] 0.6083455344070324 1.54620552432128 0.1220549397734407 1.0 0.1514337323969097 2 P51116 1
|
| 88 |
+
Polyadenylate-binding protein/Hyperplastic disc protein [IPR002004] 0.6847308678139876 1.5408908492290738 0.1233433533186274 1.0 0.1527077041352041 3 Q13310,O95071 2
|
| 89 |
+
Peptidase M16, N-terminal [IPR011765] 0.6843371833612972 1.4296314884009764 0.1528228131266391 1.0 0.1847004496121648 7 P22695,O43847,Q5JRX3,Q10713 4
|
| 90 |
+
Peptidase M16, C-terminal [IPR007863] 0.6843371833612972 1.4296314884009764 0.1528228131266391 1.0 0.1847004496121648 7 P22695,O43847,Q5JRX3,Q10713 4
|
| 91 |
+
ABC transporter type 1, transmembrane domain [IPR011527] 0.7313018160454245 1.4082237613508757 0.1590648223953581 1.0 0.1921450389514543 4 P08183,O75027 2
|
| 92 |
+
Target SNARE coiled-coil homology domain [IPR000727] 0.6935027968833021 1.3799224608348868 0.1676105201506121 1.0 0.2018742233627856 6 O15400,Q13190,Q9UEU0 3
|
| 93 |
+
Heat shock protein DnaJ, cysteine-rich domain [IPR001305] 0.6481142438667156 1.369140279736282 0.1709554294721667 1.0 0.2055514561367195 3 O60884,Q96EY1 2
|
| 94 |
+
Major sperm protein (MSP) domain [IPR000535] 0.6430499427580569 1.3453081220774858 0.1785257517466276 1.0 0.2141566160549677 3 Q9P0L0 1
|
| 95 |
+
Mad3/Bub1 homology region 1 [IPR013212] 0.5647877013177229 1.3170303465264306 0.1878284526913822 1.0 0.2244521172130898 2 O43683 1
|
| 96 |
+
Agenet-like domain [IPR008395] 0.6314808547114661 1.2908267567078424 0.1967637575070089 1.0 0.2342903486888657 3 Q06787 1
|
| 97 |
+
Fxr1, tudor domain [IPR041560] 0.6314808547114661 1.2908267567078424 0.1967637575070089 1.0 0.2342903486888657 3 Q06787 1
|
| 98 |
+
Fragile X-related 1 protein, C-terminal core [IPR022034] 0.6314808547114661 1.2908267567078424 0.1967637575070089 1.0 0.2342903486888657 3 Q06787 1
|
| 99 |
+
Synaptic functional regulator FMRP, KH0 domain [IPR040472] 0.6314808547114661 1.2908267567078424 0.1967637575070089 1.0 0.2342903486888657 3 Q06787 1
|
| 100 |
+
Zinc finger, RanBP2-type [IPR001876] 0.6347305737672788 1.2891908944465629 0.1973317298113781 1.0 0.2348468853769459 8 P35637,Q01844,Q92804 3
|
| 101 |
+
FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179] 0.6039178729081947 1.2336599150264895 0.2173296566936373 1.0 0.2568141439168235 9 P62942,Q9NWM8 2
|
| 102 |
+
Lamin tail domain [IPR001322] 0.6162577810325889 1.219106792768636 0.2228036620463851 1.0 0.2628835527429556 3 Q03252,P02545 2
|
| 103 |
+
Ubiquitin carboxyl-terminal hydrolase, C-terminal [IPR029346] 0.6107652874404981 1.193237037391667 0.2327765531870573 1.0 0.2738202779303672 3 Q93009,P51784 2
|
| 104 |
+
ZU5 domain [IPR000906] 0.5406295754026438 1.1895603014877565 0.2342192568036383 1.0 0.2753786327474801 2 Q12955 1
|
| 105 |
+
Ribosomal protein S10 domain [IPR027486] 0.5344070278184542 1.1567646171905832 0.2473685415062263 1.0 0.2901082593757099 2 P60866 1
|
| 106 |
+
TRASH domain [IPR011017] 0.5333089311859533 1.1509805115284966 0.2497402531680448 1.0 0.292449092852249 2 Q9UBW7 1
|
| 107 |
+
R3H domain [IPR001374] 0.5983592706251406 1.1348527075017107 0.2564370378898064 1.0 0.2992406214256362 3 Q9H6S0 1
|
| 108 |
+
NUC153 [IPR012580] 0.5285505124451022 1.125930334674054 0.2601950081851409 1.0 0.3033226880241159 2 Q9H501 1
|
| 109 |
+
CBS domain [IPR000644] 0.6367680453407416 1.1244036619990414 0.2608418192341588 1.0 0.3039249740078646 6 P51790 1
|
| 110 |
+
GTP binding protein, second domain [IPR031662] 0.5223279648609146 1.0932141441783785 0.274299788293709 1.0 0.3183349928756514 2 Q9Y295 1
|
| 111 |
+
Peptidase S9, prolyl oligopeptidase, catalytic domain [IPR001375] 0.6557703602383066 1.0869932447123205 0.2770397951527354 1.0 0.3213551523505402 4 P48147,Q86TI2 2
|
| 112 |
+
SKP1 component, POZ domain [IPR016073] 0.5208638360175764 1.0855242733993336 0.2776895188981192 1.0 0.3219488712150488 2 P63208 1
|
| 113 |
+
PDZ domain [IPR001478] 0.4481263212649886 1.0528455288747545 0.2924117944619344 1.0 0.3361799803390531 16 O14936,Q14168,Q00013,Q9NZW5 4
|
| 114 |
+
Legume-like lectin [IPR005052] 0.5091508052708726 1.0241427848143472 0.3057678384199724 1.0 0.3498127891771855 2 Q12907 1
|
| 115 |
+
SPRY domain [IPR003877] 0.5254118557792 1.020683272608775 0.3074045221314063 1.0 0.3513409491810249 11 P14373,Q9BUJ2,Q1KMD3,Q12899 4
|
| 116 |
+
B30.2/SPRY domain [IPR001870] 0.5254118557792 1.020683272608775 0.3074045221314063 1.0 0.3513409491810249 11 P14373,Q9BUJ2,Q1KMD3,Q12899 4
|
| 117 |
+
Dynamin-type guanine nucleotide-binding (G) domain [IPR030381] 0.5821132812862996 0.9526255566539052 0.3407798236718333 1.0 0.3865227996911349 7 P50570,O60313,Q8IWA4 3
|
| 118 |
+
Dynamin, N-terminal [IPR045063] 0.5821132812862996 0.9526255566539052 0.3407798236718333 1.0 0.3865227996911349 7 P50570,O60313,Q8IWA4 3
|
| 119 |
+
RAD23A/RAD23B, UBA1 domain [IPR041811] 0.4952415812591604 0.9516647932093932 0.3412670099979817 1.0 0.3865227996911349 2 P54725 1
|
| 120 |
+
XPC-binding domain [IPR015360] 0.4952415812591604 0.9516647932093932 0.3412670099979817 1.0 0.3865227996911349 2 P54725 1
|
| 121 |
+
TRIAD supradomain [IPR044066] 0.4901171303074783 0.9251073922742814 0.3549100482194598 1.0 0.3997660215110654 2 Q9Y4X5 1
|
| 122 |
+
IBR domain [IPR002867] 0.4901171303074783 0.9251073922742814 0.3549100482194598 1.0 0.3997660215110654 2 Q9Y4X5 1
|
| 123 |
+
Sec63 domain [IPR004179] 0.5521786891248629 0.919115024392776 0.3580354114895678 1.0 0.403091941093607 3 O75643,Q9UGP8 2
|
| 124 |
+
Sec23, C-terminal [IPR037550] 0.4886530014641365 0.917536201597041 0.3588617317704949 1.0 0.4038275391248702 2 Q15436 1
|
| 125 |
+
CTLH, C-terminal LisH motif [IPR006595] 0.4879209370424667 0.913753523260608 0.360846372901372 1.0 0.4058044997183341 2 Q96S59 1
|
| 126 |
+
ELM2 domain [IPR000949] 0.4853587115666288 0.9005299666468155 0.3678382853412578 1.0 0.4129338443614601 2 Q13330 1
|
| 127 |
+
Metastasis-associated protein MTA1, R1 domain [IPR035170] 0.4853587115666288 0.9005299666468155 0.3678382853412578 1.0 0.4129338443614601 2 Q13330 1
|
| 128 |
+
Zinc finger, CCHC-type [IPR001878] 0.5701939903063045 0.8974404154684252 0.3694839547137827 1.0 0.4145819482252199 7 Q9BWF3,Q15637,Q9BQ04,Q9NUD5 4
|
| 129 |
+
JAB1/MPN/MOV34 metalloenzyme domain [IPR000555] 0.5419303290866514 0.8400508630739906 0.4008798688341377 1.0 0.4457402351084341 8 Q7L5N1 1
|
| 130 |
+
GINS subunit, domain A [IPR021151] 0.5291102160380812 0.8132239850028622 0.4160896502312301 1.0 0.4600233585653042 3 Q9BRT9,Q9Y248 2
|
| 131 |
+
ENTH domain [IPR013809] 0.4677891654465714 0.810614592868915 0.4175870339236196 1.0 0.4614603522061769 2 Q14677 1
|
| 132 |
+
Chromo shadow domain [IPR008251] 0.5228853899670451 0.7849843875127468 0.4324627224339687 1.0 0.4767707539581289 3 Q13185,P45973 2
|
| 133 |
+
Chromo domain subgroup [IPR017984] 0.5228853899670451 0.7849843875127468 0.4324627224339687 1.0 0.4767707539581289 3 Q13185,P45973 2
|
| 134 |
+
ABC transporter-like, ATP-binding domain [IPR003439] 0.5449778691646638 0.7818028871852637 0.4343304240181598 1.0 0.4786038414735267 7 P08183,O75027 2
|
| 135 |
+
Lens epithelium-derived growth factor, integrase-binding domain [IPR021567] 0.4608345534407156 0.7754550097134539 0.4380708405120046 1.0 0.4820430785087327 2 Q7Z4V5 1
|
| 136 |
+
LEM domain [IPR003887] 0.5570047894396545 0.7691659804296207 0.4417947831793176 1.0 0.4859118317115905 6 P42167,Q86XL3 2
|
| 137 |
+
Class I myosin, motor domain [IPR036072] 0.4593704245973684 0.7680890323350154 0.4424342923666633 1.0 0.4861572106711336 2 O94832 1
|
| 138 |
+
Class I myosin tail homology domain [IPR010926] 0.4593704245973684 0.7680890323350154 0.4424342923666633 1.0 0.4861572106711336 2 O94832 1
|
| 139 |
+
EF-hand domain [IPR002048] 0.3316543996655238 0.7561121744982016 0.4495819432231089 1.0 0.4932924681517656 42 O95202,O43852,P80303,Q14257,Q9NWM8,Q9BRK5,Q02818,Q9Y680 8
|
| 140 |
+
AMP-binding enzyme, C-terminal domain [IPR025110] 0.4542459736456934 0.7424141992277671 0.4578364191360493 1.0 0.5011945797855955 2 Q6P1M0 1
|
| 141 |
+
PTB/PI domain [IPR006020] 0.5111680703039179 0.7323028989223413 0.4639837103336839 1.0 0.5073922097903053 3 Q9UKG1,Q9Y3P9 2
|
| 142 |
+
Nucleotidyl transferase domain [IPR005835] 0.5090736424680631 0.7229582835139601 0.4697055139996686 1.0 0.5120272526560347 3 Q9Y5P6 1
|
| 143 |
+
Pleckstrin homology domain [IPR001849] 0.3827253364824613 0.7108016404250032 0.4772071639591271 1.0 0.5197195558976501 19 P31751,Q9BZF3 2
|
| 144 |
+
HECT domain [IPR000569] 0.5377109093742541 0.6857577909684003 0.4928658572188544 1.0 0.535275244933035 6 Q05086,Q96J02 2
|
| 145 |
+
Ribosomal protein L18e/L15P [IPR021131] 0.5005492493592092 0.6851749675230532 0.4932335180518168 1.0 0.535425506578797 3 P46776,Q9P015 2
|
| 146 |
+
Arginyl-tRNA synthetase, catalytic core domain [IPR035684] 0.4418008784773016 0.6808188891854224 0.4959860962861477 1.0 0.5379133928602671 2 Q5T160 1
|
| 147 |
+
DALR anticodon binding [IPR008909] 0.4418008784773016 0.6808188891854224 0.4959860962861477 1.0 0.5379133928602671 2 Q5T160 1
|
| 148 |
+
SCP2 sterol-binding domain [IPR003033] 0.4965214207250094 0.6674708426136371 0.5044714280443552 1.0 0.5458483709377059 3 Q6YN16,P51659 2
|
| 149 |
+
Exonuclease, RNase T/DNA polymerase III [IPR013520] 0.434114202049775 0.6433812090951598 0.5199767733162952 1.0 0.5616392370313575 2 Q9GZR2 1
|
| 150 |
+
RNA recognition motif domain, eukaryote [IPR003954] 0.4059956958481317 0.5923904648431271 0.5535891499184287 1.0 0.5937669568486591 13 P31483,Q01085,P38159 3
|
| 151 |
+
CAP Gly-rich domain [IPR000938] 0.4209370424597333 0.5804562844883172 0.5616069585635644 1.0 0.6020901047961078 2 Q15813 1
|
| 152 |
+
Glutamine amidotransferase [IPR017926] 0.5258376129202335 0.5550281515038261 0.5788754050915914 1.0 0.6186151354182453 4 P17812 1
|
| 153 |
+
Peptidase C19, ubiquitin-specific peptidase, DUSP domain [IPR006615] 0.466495789088246 0.53909331570259 0.5898224675774597 1.0 0.6300253713601869 3 Q9Y4E8,P51784 2
|
| 154 |
+
Immunoglobulin I-set [IPR013098] 0.4110541727672014 0.5344471603567538 0.5930321979358091 1.0 0.6328748547441108 2 Q13308 1
|
| 155 |
+
SPRY-associated [IPR006574] 0.4974170848374865 0.5177888809710584 0.6046055770036789 1.0 0.6431681195004967 6 P14373,P19474,Q12899 3
|
| 156 |
+
Butyrophylin-like, SPRY domain [IPR003879] 0.4974170848374865 0.5177888809710584 0.6046055770036789 1.0 0.6431681195004967 6 P14373,P19474,Q12899 3
|
| 157 |
+
Exportin-2, central domain [IPR013713] 0.4452581471988284 0.4530188307831777 0.6505351819465641 1.0 0.6876413082142269 3 P55060,O95373 2
|
| 158 |
+
Helicase/UvrB, N-terminal [IPR006935] 0.4379348224093739 0.4244433792899105 0.6712424901647511 1.0 0.707288454212407 3 P19447,Q9UPY3 2
|
| 159 |
+
Myosin tail [IPR002928] 0.4335408275357013 0.407599043252338 0.6835680668327782 1.0 0.7183309793224739 3 P35580,P35579 2
|
| 160 |
+
Glutamine amidotransferase type 2 domain [IPR017932] 0.4298791651409741 0.3937423747991112 0.6937712527506161 1.0 0.7276380139489068 3 Q06203,Q06210 2
|
| 161 |
+
MPN domain [IPR037518] 0.4313934007445313 0.3934558748210363 0.6939828081645463 1.0 0.7276380139489068 9 Q7L5N1 1
|
| 162 |
+
YTH domain [IPR007275] 0.474443907303716 0.3693334685735206 0.7118791819312646 1.0 0.744730237369849 4 Q96MU7,Q9H6S0 2
|
| 163 |
+
Transcription factor CBF/NF-Y/archaeal histone domain [IPR003958] 0.4082753570120835 0.3156065777236735 0.7523011443938066 1.0 0.7835072132736567 3 Q9NR33,Q9NRF9 2
|
| 164 |
+
Adenylate kinase, active site lid domain [IPR007862] 0.356881405563685 0.3064277704415185 0.7592789668962632 1.0 0.7900696914896499 2 P27144 1
|
| 165 |
+
TGS [IPR004095] 0.4408580573622445 0.3042468703918723 0.7609398188343564 1.0 0.7913871775697472 6 Q9NYK5,Q9BW92,Q9Y295 3
|
| 166 |
+
Coatomer, gamma subunit, appendage, Ig-like subdomain [IPR013040] 0.3495607613469923 0.2795229572535964 0.7798435225171203 1.0 0.8093042778122116 2 Q9Y678 1
|
| 167 |
+
Coatomer subunit gamma, C-terminal [IPR032154] 0.3495607613469923 0.2795229572535964 0.7798435225171203 1.0 0.8093042778122116 2 Q9Y678 1
|
| 168 |
+
JmjC domain [IPR003347] 0.4457792314972886 0.2771471210667517 0.7816671409687772 1.0 0.8108364167756974 4 Q8IUF8 1
|
| 169 |
+
Acyl-CoA oxidase/dehydrogenase, central domain [IPR006091] 0.4225528507445468 0.2733517312360619 0.7845828531240162 1.0 0.8131384651773538 7 O15254,Q15067 2
|
| 170 |
+
Zinc finger, GATA-type [IPR000679] 0.4384615384615401 0.2552127356798112 0.7985587950503472 1.0 0.8261563076838994 4 Q86YP4,Q13330,O94776 3
|
| 171 |
+
Ricin B, lectin domain [IPR000772] 0.436633815786797 0.2498435858551528 0.802708311724345 1.0 0.8300814472437315 4 Q86SF2,Q9UBG0 2
|
| 172 |
+
B-box-type zinc finger [IPR000315] 0.4001184554926129 0.2271572801053306 0.8203014449110004 1.0 0.846546820017155 8 P14373,O15164,Q12899 3
|
| 173 |
+
ATP-dependent RNA helicase eIF4A, DEAD-box helicase domain [IPR044728] 0.3169838945827155 0.1738389309475965 0.8619920477124603 1.0 0.8847259039158658 2 Q14240 1
|
| 174 |
+
MCM N-terminal domain [IPR027925] 0.3907624633431089 0.1482615861781141 0.8821363300490748 1.0 0.9018337699932528 6 P49736,Q14566,P25205,P33993,P33992 5
|
| 175 |
+
MCM domain [IPR001208] 0.3907624633431089 0.1482615861781141 0.8821363300490748 1.0 0.9018337699932528 6 P49736,Q14566,P25205,P33993,P33992 5
|
| 176 |
+
MCM, AAA-lid domain [IPR041562] 0.3907624633431089 0.1482615861781141 0.8821363300490748 1.0 0.9018337699932528 6 P49736,Q14566,P25205,P33993,P33992 5
|
| 177 |
+
MCM OB domain [IPR033762] 0.3907624633431089 0.1482615861781141 0.8821363300490748 1.0 0.9018337699932528 6 P49736,Q14566,P25205,P33993,P33992 5
|
| 178 |
+
Circularly permuted (CP)-type guanine nucleotide-binding (G) domain [IPR030378] 0.3933824930032514 0.1366494015573671 0.8913079259327101 1.0 0.909219749695447 4 Q13823 1
|
| 179 |
+
Chaperone DnaJ, C-terminal [IPR002939] 0.3808312102713607 0.1091366841564664 0.913094078905206 1.0 0.9286039521967144 4 O60884,Q96EY1 2
|
| 180 |
+
Protein kinase domain [IPR000719] 0.2613158749128542 0.0975671067633197 0.9222760448503317 1.0 0.9367179489889188 46 Q99640,P48729,P11802,P31751,P36507,O14936,Q13153,Q13555,Q13546 9
|
| 181 |
+
DnaJ domain [IPR001623] 0.3035648658581481 0.0715641322660529 0.9429487851619917 1.0 0.9552214374634492 13 Q9NVH1,P31689,Q99543,Q13217,P25685,Q96EY1,Q9UGP8,Q96KC8,O75937,Q99615,O60884,Q8IXB1 12
|
| 182 |
+
Importin-beta, N-terminal domain [IPR001494] 0.3009450749496483 0.0612762660875588 0.9511391921937556 1.0 0.9626831442446552 13 Q8TEX9 1
|
| 183 |
+
Aminotransferase, class I/classII [IPR004839] 0.3372552454869781 0.0317834065121777 0.9746447796363156 1.0 0.9843406403333896 7 Q6YP21 1
|
| 184 |
+
Zinc finger, RING-type [IPR001841] 0.2710520145081824 0.0050218846867569 0.9959931325840604 1.0 1.0 20 P14373,O15164,Q12899,P19474,Q14527 5
|