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- interpro_active_site/advanced/idx2term.json +1 -0
- interpro_active_site/advanced/plot_0.png +3 -0
- interpro_active_site/basic/idx2term.json +1 -0
- interpro_active_site/basic/plot_0.png +3 -0
- interpro_active_site/consensus.joblib +3 -0
- interpro_active_site/df_merge.tsv +3 -0
- interpro_active_site/metrics.json +7 -0
- interpro_active_site/paths.json +1 -0
- interpro_active_site/result.tsv +9 -0
- interpro_active_site/selections.json +1 -0
- interpro_binding_site/advanced/idx2term.json +1 -0
- interpro_binding_site/basic/idx2term.json +1 -0
- interpro_binding_site/basic/plot_0.png +3 -0
- interpro_binding_site/consensus.joblib +3 -0
- interpro_binding_site/df_merge.tsv +1 -0
- interpro_binding_site/metrics.json +7 -0
- interpro_binding_site/paths.json +1 -0
- interpro_binding_site/result.tsv +4 -0
- interpro_binding_site/selections.json +1 -0
- interpro_conserved_site/advanced/idx2term.json +1 -0
- interpro_conserved_site/advanced/plot_0.png +3 -0
- interpro_conserved_site/advanced/plot_1.png +3 -0
- interpro_conserved_site/advanced/plot_2.png +3 -0
- interpro_conserved_site/basic/idx2term.json +1 -0
- interpro_conserved_site/basic/plot_0.png +3 -0
- interpro_conserved_site/basic/plot_1.png +3 -0
- interpro_conserved_site/basic/plot_2.png +3 -0
- interpro_conserved_site/consensus.joblib +3 -0
- interpro_conserved_site/df_merge.tsv +6 -0
- interpro_conserved_site/metrics.json +7 -0
- interpro_conserved_site/paths.json +1 -0
- interpro_conserved_site/result.tsv +39 -0
- interpro_conserved_site/selections.json +1 -0
- interpro_domain/advanced/idx2term.json +1 -0
- interpro_domain/advanced/plot_0.png +3 -0
- interpro_domain/advanced/plot_1.png +3 -0
- interpro_domain/advanced/plot_2.png +3 -0
- interpro_domain/advanced/plot_3.png +3 -0
- interpro_domain/advanced/plot_4.png +3 -0
- interpro_domain/advanced/plot_5.png +3 -0
- interpro_domain/advanced/plot_6.png +3 -0
- interpro_domain/advanced/plot_7.png +3 -0
- interpro_domain/advanced/plot_8.png +3 -0
- interpro_domain/advanced/plot_9.png +3 -0
- interpro_domain/basic/idx2term.json +1 -0
- interpro_domain/basic/plot_0.png +3 -0
- interpro_domain/basic/plot_1.png +3 -0
- interpro_domain/basic/plot_10.png +3 -0
- interpro_domain/basic/plot_11.png +3 -0
- interpro_domain/basic/plot_12.png +3 -0
interpro_active_site/advanced/idx2term.json
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{"0": "Tyrosine-protein kinase, active site [IPR008266]"}
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interpro_active_site/advanced/plot_0.png
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interpro_active_site/basic/idx2term.json
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{"0": "Tyrosine-protein kinase, active site [IPR008266]"}
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interpro_active_site/basic/plot_0.png
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interpro_active_site/consensus.joblib
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version https://git-lfs.github.com/spec/v1
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oid sha256:c2c06a8e07f8d0b8c18423a50199c0a4f64864cfb63838d00f35bb385b51bdac
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interpro_active_site/df_merge.tsv
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term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500
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Cysteine peptidase, cysteine active site [IPR000169] 3 7 2.454565576623616 0.0141054934786972 1.9927184466019416 4.106796116504855 -0.4055096631049736 0.4078826502023353 1.2157723137108922 1.0442874781746152 1.1544656254210668 0.3023405414752508 0.0001491979893058 1.7811480551971096e-05 0.0001343549216781 9.549361773523036e-05 0.0013678067399173
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Tyrosine-protein kinase, active site [IPR008266] 5 8 2.1863750752917324 0.0287881755976573 1.966019417475728 4.424757281553398 -0.1200516463743167 0.6230089636210521 1.361328120641804 1.7240921881171525 0.7701660211075021 0.2916799688715877 0.0547124941924187 1.0 1.0 0.3670688568616856 0.1125319425951153
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interpro_active_site/metrics.json
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{
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"type_of_task": "ranksum",
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"signature_size": 3725,
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"annotations_size": 60,
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"title": "Average number of proteins per term",
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"value": 3.0833333333333335
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}
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interpro_active_site/paths.json
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{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C170/C170_val_log2fc"}
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interpro_active_site/result.tsv
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Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
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Cysteine peptidase, cysteine active site [IPR000169] 0.903234098546114 2.4545655766236156 0.0141054934786972 0.5735905685847447 0.0846329608721836 7 P07711,P53634,P07858 3
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Cysteine peptidase, histidine active site [IPR025660] 0.9588820209621014 2.207245971045987 0.027296879674961 0.8099715863867478 0.0959605853255244 4 P07711,P53634,P07858 3
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Tyrosine-protein kinase, active site [IPR008266] 0.8198355662143418 2.1863750752917324 0.0287881755976573 0.8266843919311778 0.0959605853255244 8 P29317,P23458,Q15375,P00533,P07947 5
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Cysteine peptidase, asparagine active site [IPR025661] 0.990059108006448 1.733471643888205 0.083011873261201 0.9944814784239084 0.19382837455086 3 P07711,P07858 2
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Serine carboxypeptidase, serine active site [IPR018202] 0.9793121977431484 1.6930116933471524 0.090453241457068 0.996615443041714 0.19382837455086 3 Q9HB40,P10619 2
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Protein-tyrosine phosphatase, active site [IPR016130] 0.649750985339087 1.4964508307385205 0.1345362119096613 0.9998282352366452 0.2522553973306151 9 Q9NYA4,P10586,Q13614 3
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Peptidase S16, active site [IPR008268] 0.5401557883427216 0.1970549451724033 0.8437845406012432 1.0 0.9040548649299034 2 P36776 1
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Adenosine/AMP deaminase active site [IPR006650] 0.4023636852000979 0.0638263690741692 0.949108481577531 1.0 0.981967429044786 2 Q01433 1
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interpro_active_site/selections.json
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{"all_annotations": ["ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenosine/AMP deaminase active site [IPR006650]", "Adenylosuccinate synthase, active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Coenzyme A transferase active site [IPR004164]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "DNA topoisomerase, type IA, active site [IPR023406]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glutaredoxin active site [IPR011767]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycoside hydrolase, family 2, active site [IPR023232]", "Glycosyl hydrolases family 18 (GH18) active site [IPR001579]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Lipase, GDXG, putative serine active site [IPR033140]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Peptidase family C14A, His active site [IPR016129]", "Peptidase family C14A, cysteine active site [IPR033139]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]", "Uracil-DNA glycosylase, active site [IPR018085]"], "available_proteins": ["AAK1", "ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADA", "ADSS", "AKT2", "AMPD2", "APEH", "ARAF", "ATP5A1", "ATP5B", "ATP6V1A", "ATP6V1B2", "AURKA", "AURKB", "BLMH", "CAMK1", "CAMK2G", "CAPN1", "CAPN2", "CASP8", "CDC42BPB", "CDK1", "CDK11B", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CDK7", "CDK9", "CHEK1", "CHEK2", "CHUK", "CIT", "CKB", "CKMT1A*", "CLK2", "CLK3", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CTBS", "CTSA", "CTSB", "CTSC", "CTSF", "CTSL", "DLD", "DNMT1", "DUSP3", "EGFR", "EIF2AK2", "EPHA2", "EPHA7", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLRX", "GLUD1", "GSK3A", "GSR", "GUSB", "HADHB", "HMGCL", "HMGCS1", "IGF1R", "JAK1", "LDHA", "LDHB", "LONP1", "LONP2", "MAP2K1", "MAP3K4", "MAP3K7", "MAP4K4", "MAPK1", "MAPK3", "MARK2", "MDH1", "MDH2", "MTMR14", "MTMR2", "MTMR4", "MTMR6", "NCEH1", "NEK9", "NME1", "NME2", "NME3", "NME4", "OXCT1", "PAK2", "PBK", "PGAM1", "PIK3R4", "PKM", "PKMYT1", "PKN1", "PKN2", "PLK1", "PREP", "PRKAA1", "PRKAA2", "PRKACA", "PRKACB", "PRKCA", "PRKCD", "PRPF4B", "PTK7", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "RIPK1", "RNASET2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "RRM2", "RRM2B", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SRPK2", "SUCLG1", "TALDO1", "TIGAR", "TOP1", "TOP3A", "TPI1", "TPP2", "TRIO", "TTK", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "ULK3", "UMPS", "UNG", "VRK1", "VRK2", "WNK1", "WNK2", "YES1"], "leading_proteins": ["AMPD2", "CTSA", "CTSB", "CTSC", "CTSL", "EGFR", "EPHA2", "EPHA7", "JAK1", "LONP1", "MTMR2", "MTMR4", "PTPRF", "SCPEP1", "YES1"]}
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interpro_binding_site/advanced/idx2term.json
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{}
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interpro_binding_site/basic/idx2term.json
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{"0": "EF-Hand 1, calcium-binding site [IPR018247]"}
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interpro_binding_site/basic/plot_0.png
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interpro_binding_site/consensus.joblib
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version https://git-lfs.github.com/spec/v1
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oid sha256:5805e5271e00b3af251530e2a0db284e6df01c4208d19ae3a9ba8895cfb44f2a
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size 83477
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interpro_binding_site/df_merge.tsv
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term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500
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interpro_binding_site/metrics.json
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{
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"type_of_task": "ranksum",
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"signature_size": 3725,
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"annotations_size": 34,
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"title": "Average number of proteins per term",
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"value": 4.9411764705882355
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}
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interpro_binding_site/paths.json
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{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C170/C170_val_log2fc"}
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interpro_binding_site/result.tsv
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Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
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Beta tubulin, autoregulation binding site [IPR013838] 0.7337477658983325 1.3110557913124314 0.1898389151782589 0.9992211983391336 0.6043633634168663 4 P07437,Q9BVA1 2
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EF-Hand 1, calcium-binding site [IPR018247] 0.4261648524050421 1.0967180668063998 0.2727646561647563 0.9999801870457402 0.6286426971532272 39 Q14257,Q9H4M9,P43304,Q15293,P80303,O43852,Q9NWM8,P0DP25,P31949,Q9H223,Q9Y680,Q02818 12
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Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917] 0.6604888530754729 0.4989861126623894 0.6177891674696956 0.9999999999999936 0.7764261781645709 2 O75600 1
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interpro_binding_site/selections.json
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{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "APOBEC/CMP deaminase, zinc-binding [IPR016192]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Aryldialkylphosphatase, zinc-binding site [IPR017947]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Coenzyme A transferase binding site [IPR004163]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Legume lectin, beta chain, Mn/Ca-binding site [IPR019825]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]", "Ureohydrolase, manganese-binding site [IPR020855]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "AKT2", "APEX1", "ARAF", "ARG2", "AURKA", "AURKB", "BPNT1", "CALM3", "CALU", "CAMK1", "CAMK2G", "CAPN1", "CAPN2", "CDC42BPB", "CDK1", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CDK7", "CDK9", "CETN2", "CHEK1", "CHUK", "CIT", "CLK2", "CLK3", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A2", "CYB5B", "DBT", "DCTD", "DLAT", "DLST", "DST", "EGFR", "EHD1", "EHD4", "EIF2AK2", "EPHA2", "EPHA7", "EPS15", "EPS15L1", "FKBP10", "FKBP14", "FKBP7", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3A", "HK1", "HK2", "HMBS", "IDE", "IGF1R", "ILKAP", "IQCB1", "IQGAP1", "IQGAP2", "IQGAP3", "ITSN2", "JAK1", "LETM1", "LRP2", "MACF1", "MAP2K1", "MAP3K4", "MAP3K7", "MAP4K4", "MAPK1", "MAPK14", "MAPK3", "MARK2", "MCCC1", "METAP2", "MICU1", "MYH10", "MYH14", "MYH9", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "NFS1", "NRDC", "NUCB1", "NUCB2", "OXCT1", "PA2G4", "PAK2", "PC", "PCCA", "PDCD6", "PDHX", "PDP1", "PEF1", "PGD", "PKMYT1", "PKN1", "PKN2", "PLCG1", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1G", "PRKAA1", "PRKAA2", "PRKACA", "PRKACB", "PRKCA", "PRKCD", "PRKCSH", "PSAT1", "PTER", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "S100A11", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "SRPK2", "STK26", "STK3", "STK4", "TKT", "TTK", "TUBB", "TUBB2B", "TUBB4B", "TUBB6", "UBE3C", "ULK3", "UQCRC2", "USP32", "VRK1", "YES1"], "leading_proteins": ["CALM3", "CALU", "EHD1", "EHD4", "FKBP14", "FKBP7", "GCAT", "GPD2", "NUCB1", "NUCB2", "RCN1", "RCN2", "S100A11", "TUBB", "TUBB2B"]}
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{"0": "EGF-like calcium-binding, conserved site [IPR018097]", "1": "Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415]", "2": "Guanylate kinase, conserved site [IPR020590]"}
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interpro_conserved_site/advanced/plot_0.png
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interpro_conserved_site/advanced/plot_1.png
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interpro_conserved_site/advanced/plot_2.png
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interpro_conserved_site/basic/idx2term.json
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{"0": "EGF-like calcium-binding, conserved site [IPR018097]", "1": "Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415]", "2": "Guanylate kinase, conserved site [IPR020590]"}
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interpro_conserved_site/basic/plot_0.png
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Git LFS Details
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interpro_conserved_site/basic/plot_1.png
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Git LFS Details
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interpro_conserved_site/basic/plot_2.png
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Git LFS Details
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interpro_conserved_site/consensus.joblib
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version https://git-lfs.github.com/spec/v1
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oid sha256:2174e1465396c20ba0724bb00564c40f3bfc32e29820da639dc0f7e8e40f1dff
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size 103756
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interpro_conserved_site/df_merge.tsv
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term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500
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EGF-like calcium-binding, conserved site [IPR018097] 8 9 2.77416866159014 0.0055342977658552 1.1703703703703705 2.466666666666667 -0.1373915694631231 0.3902853831950666 1.067180945982341 1.5160051467387146 1.437469353479462 0.3143260829565273 4.383365728727184e-07 0.1665759675679584 0.0004155585626268 1.6510644959116593e-07 5.0413761780603096e-05
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Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415] 5 6 2.5516565782471137 0.0107212137866889 1.062730627306273 1.845018450184502 -0.374757291558179 0.2572252390798428 0.9906082579891434 1.2202031996221276 1.9499632968198624 0.2932843562524823 3.587650196088784e-06 0.0802348466038066 4.180168207037102e-07 1.837861939916845e-06 9.825976589410204e-05
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Syntaxin/epimorphin, conserved site [IPR006012] 3 5 2.010155874905289 0.0444146938838556 2.592233009708738 5.847087378640777 0.9961908981999794 0.2839139128702306 1.4759357288864456 1.4239341993278547 1.138258151200134 0.2914162845337057 0.0003096916980164 1.0 1.0 0.0033170374819039 0.0027426851014433
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Cadherin conserved site [IPR020894] 3 5 1.9858496000853636 0.0470500264025308 1.555825242718447 3.0558252427184467 -0.2693089236279177 0.4378099575304214 1.0377767725547085 1.0517161419538543 1.2797396443463749 0.3315735399503712 0.0118457633601407 1.0 0.1596960736798767 0.0086586519898169 0.0096830476876922
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Guanylate kinase, conserved site [IPR020590] 5 6 1.975273626263949 0.0482371045197085 2.3980582524271843 5.25 0.6064346340666176 0.4240795168052628 1.6195996498310523 1.4740884957165508 0.9685287933135084 0.3034897017004088 1.0 1.0 1.0 1.0 0.0139360561882317
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interpro_conserved_site/metrics.json
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{
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"type_of_task": "ranksum",
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"signature_size": 3725,
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"annotations_size": 296,
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"title": "Average number of proteins per term",
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"value": 2.918918918918919
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}
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interpro_conserved_site/paths.json
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{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C170/C170_val_log2fc"}
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interpro_conserved_site/result.tsv
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Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
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EGF-like calcium-binding, conserved site [IPR018097] 0.9418729817007612 2.77416866159014 0.0055342977658552 0.8065433734762143 0.1905708099392817 9 P48960,P01130,Q14517,P14543,O94813,Q07954,P98164,P98155 8
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Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415] 0.9688088195751524 2.5516565782471137 0.0107212137866889 0.958853385737268 0.1905708099392817 6 P01130,Q9NPF0,Q92673,P98164,P98155 5
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Sulfatase, conserved site [IPR024607] 0.9478634775597896 2.1648146177806 0.0304018849114293 0.9998925610601078 0.249971053716197 4 P34059,P15289,P15586 3
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| 5 |
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Syntaxin/epimorphin, conserved site [IPR006012] 0.8572790385922817 2.0101558749052892 0.0444146938838556 0.9999985553552512 0.2683010079514546 5 O43752,Q86Y82,Q9P2W9 3
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| 6 |
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Cadherin conserved site [IPR020894] 0.8512243100370585 1.9858496000853632 0.0470500264025308 0.9999993621033842 0.274580441112187 5 Q14574,Q14517,O60245 3
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| 7 |
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Guanylate kinase, conserved site [IPR020590] 0.8238773863941808 1.975273626263949 0.0482371045197085 0.9999995589215278 0.274580441112187 6 Q9NZW5,Q00013,Q12959,Q14168,O14936 5
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| 8 |
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Amyloidogenic glycoprotein, copper-binding domain conserved site [IPR019744] 0.9863013698630148 1.7608645874052056 0.0782613249216437 0.9999999999665872 0.3073515761827814 2 P05067 1
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| 9 |
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Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745] 0.9863013698630148 1.7608645874052056 0.0782613249216437 0.9999999999665872 0.3073515761827814 2 P05067 1
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| 10 |
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Proteinase inhibitor I2, Kunitz, conserved site [IPR020901] 0.9863013698630148 1.7608645874052056 0.0782613249216437 0.9999999999665872 0.3073515761827814 2 P05067 1
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| 11 |
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C-type lectin, conserved site [IPR018378] 0.9830781627719598 1.7477195835080035 0.0805125960413475 0.9999999999837986 0.3073515761827814 2 Q5KU26 1
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| 12 |
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Tetraspanin, conserved site [IPR018503] 0.9779747515444532 1.7268958823386922 0.0841863640804914 0.9999999999950466 0.3073515761827814 2 O60637 1
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| 13 |
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Lysosome-associated membrane glycoprotein, conserved site [IPR018134] 0.9766317485898496 1.7214138791954725 0.0851757475008034 0.9999999999964028 0.3073515761827814 2 P13473 1
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| 14 |
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Glycoside hydrolase, family 29, conserved site [IPR018526] 0.9755573462261644 1.7170276793812491 0.0859741147122581 0.999999999997222 0.3073515761827814 2 Q9BTY2 1
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| 15 |
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Immunoglobulin/major histocompatibility complex, conserved site [IPR003006] 0.9642665233745292 1.6362598125345986 0.1017852230537614 0.999999999999984 0.3221279139440353 3 P55899,P04439 2
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| 16 |
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Thioredoxin, conserved site [IPR017937] 0.6363200309104422 1.6327618353728484 0.102519096655739 0.9999999999999876 0.3221279139440353 12 O43396,O95881,Q8IXB1,Q9H1E5 4
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| 17 |
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Tyrosine-protein kinase, receptor class V, conserved site [IPR001426] 0.946011281224822 1.5962427046369323 0.1104346165715912 0.9999999999999992 0.3301883485372829 2 Q15375 1
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| 18 |
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EGF-like, conserved site [IPR013032] 0.940102068224554 1.5720600910264726 0.1159366158503294 1.0 0.3331770707931797 2 O94813 1
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| 19 |
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Integrin alpha chain, C-terminal cytoplasmic region, conserved site [IPR018184] 0.9223744292237442 1.499501559236722 0.1337435645095293 1.0 0.3665564360631543 2 P17301 1
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| 20 |
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Sugar transporter, conserved site [IPR005829] 0.9167338168144048 1.476419275703749 0.1398313712263577 1.0 0.3728836566036205 2 Q7L0J3 1
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| 21 |
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Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364] 0.770835457675008 1.4617644998814583 0.1438057553600191 1.0 0.3740914456661736 4 Q8N4Q0,Q8WWV3 2
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| 22 |
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Glycoside hydrolase, family 35, conserved site [IPR019801] 0.8957829707225484 1.390759900093303 0.1642982467232392 1.0 0.40526900858399 2 P16278 1
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| 23 |
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Tubulin, conserved site [IPR017975] 0.7337477658983322 1.3110557913124314 0.1898389151782589 1.0 0.4568481210793873 4 P07437,Q9BVA1 2
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| 24 |
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Dynamin, GTPase region, conserved site [IPR019762] 0.7565824825362668 0.8591042208626387 0.3902830188367772 1.0 0.6526766868682827 3 Q05193,O00429 2
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| 25 |
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Calreticulin/calnexin, conserved site [IPR018124] 0.6874369710235905 0.6203579261243112 0.5350221660092507 1.0 0.7763066722487167 3 O14967 1
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| 26 |
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DnaJ domain, conserved site [IPR018253] 0.4222442065958056 0.5479556643518221 0.583722345888432 1.0 0.8225936352563066 13 Q99543,Q9NVH1,Q96KC8 3
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| 27 |
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Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818] 0.4590189225130934 0.3960639171520987 0.6920578762548311 1.0 0.8843331714779885 5 P48735 1
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| 28 |
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ABC transporter-like, conserved site [IPR017871] 0.3560563368061407 0.2361390969098127 0.813324736694278 1.0 0.9417097676352492 14 P08183,Q03519,P33527,O14678 4
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| 29 |
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Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326] 0.556809024979853 0.228327232509213 0.8193918551623964 1.0 0.9417097676352492 2 P29692 1
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| 30 |
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Aminotransferase, class IV, conserved site [IPR018300] 0.5549288208433996 0.2246153461193461 0.822278525450798 1.0 0.9417097676352492 2 O15382 1
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| 31 |
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Mrp, conserved site [IPR000808] 0.5490196078431401 0.2132492100464517 0.8311325868244754 1.0 0.9417097676352492 2 Q8TB37 1
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| 32 |
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Clathrin adaptor, mu subunit, conserved site [IPR018240] 0.5338527673293838 0.2092828887825556 0.8342274087881723 1.0 0.9417097676352492 3 Q9BXS5,Q96CW1 2
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| 33 |
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Procollagen-lysine 5-dioxygenase, conserved site [IPR001006] 0.5314347125201415 0.2047099708791874 0.8377987297491756 1.0 0.9417097676352492 3 Q02809,O00469 2
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| 34 |
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Serpin, conserved site [IPR023795] 0.5118216012896196 0.170145617457151 0.8648956189617467 1.0 0.9517067033928516 3 P50454,P30740 2
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| 35 |
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Oxysterol-binding protein, conserved site [IPR018494] 0.359651445991032 0.1647770986164277 0.8691194302795286 1.0 0.9528124124545944 8 Q9BXW6 1
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| 36 |
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Ubiquitin conserved site [IPR019954] 0.4758079859254815 0.1183845519376372 0.9057629654682882 1.0 0.9820726658557264 3 P46379 1
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| 37 |
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HMG box A DNA-binding domain, conserved site [IPR017967] 0.4723267060719944 0.1141686218170487 0.9091041253969938 1.0 0.9820978872901832 3 O15347,P26583 2
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| 38 |
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Heat shock protein Hsp90, conserved site [IPR019805] 0.4591617409994527 0.0994327826005489 0.9207946549767818 1.0 0.9911098831750088 3 P14625,P08238 2
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| 39 |
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Dynein light chain, type 1/2, conserved site [IPR019763] 0.4512489927477829 0.088853822111738 0.92919808294478 1.0 0.9955124257838426 2 P63167 1
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interpro_conserved_site/selections.json
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{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3'5'-cyclic nucleotide phosphodiesterase, conserved site [IPR023174]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AF4 interaction motif [IPR043639]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Adenylyl cyclase class-4/guanylyl cyclase, conserved site [IPR018297]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Alpha-2-macroglobulin, conserved site [IPR019742]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Aminotransferase, class IV, conserved site [IPR018300]", "Amyloidogenic glycoprotein, copper-binding domain conserved site [IPR019744]", "Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]", "Anion exchange, conserved site [IPR018241]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Band 7/stomatin-like, conserved site [IPR018080]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAMSAP, spectrin and Ca2+/calmodulin-binding region [IPR031372]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "CBX family C-terminal motif [IPR033773]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Copper type II, ascorbate-dependent monooxygenase, histidine-cluster-1 conserved site [IPR020611]", "Copper type II, ascorbate-dependent monooxygenase, histidine-cluster-2 conserved site [IPR014783]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific, conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA mismatch repair, conserved site [IPR014762]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family A, conserved site [IPR019760]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dpy-30 motif [IPR007858]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Ependymin, conserved site [IPR018224]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "FeS cluster insertion, C-terminal, conserved site [IPR017870]", "Ferritin, conserved site [IPR014034]", "Fibrillarin, conserved site [IPR020813]", "Fork head domain conserved site 2 [IPR030456]", "Fork head domain conserved site1 [IPR018122]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GPCR, family 2, secretin-like, conserved site [IPR017983]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glutathione peroxidase conserved site [IPR029760]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 2, conserved site [IPR023230]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Golgin subfamily A member 2, C-terminal binding motif [IPR043937]", "Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Heavy-metal-associated, conserved site [IPR017969]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Helix-turn-helix motif [IPR000047]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "Homeobox, conserved site [IPR017970]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Integrin alpha chain, C-terminal cytoplasmic region, conserved site [IPR018184]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kank N-terminal motif [IPR021939]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "MoaA/NifB/PqqE, iron-sulphur binding, conserved site [IPR000385]", "Molybdenum cofactor biosynthesis, conserved site [IPR008284]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosyl pyrophosphate synthetase, conserved site [IPR000842]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RIO kinase, conserved site [IPR018935]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Rel homology domain, conserved site [IPR030492]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P, conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S14, conserved site [IPR018271]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium/solute symporter, conserved site [IPR018212]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Transcription factor TFIIB, conserved site [IPR023486]", "Transcription factor, T-box, conserved site [IPR018186]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Tubulin, conserved site [IPR017975]", "Tyrosine-protein kinase, receptor class II, conserved site [IPR002011]", "Tyrosine-protein kinase, receptor class V, conserved site [IPR001426]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Uncharacterised protein family UPF0029, Impact, conserved site [IPR020569]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]", "tRNA-dihydrouridine synthase, conserved site [IPR018517]"], "available_proteins": ["AAAS", "AAMP", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADCY3", "ADGRE5", "ADH5", "ADK", "ADSL", "AFF4", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK3", "AK4", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1M1", "AP1S2", "AP2M1", "AP2S1", "AP3M1", "AP3S1", "APEX1", "APLP2", "APP", "ARSA", "ATAD1", "ATAD2", "ATM", "ATP5C1", "ATP5O", "ATP7A", "BAG6", "BAK1", "BARD1", "BAZ1A", "BAZ1B", "BAZ2A", "BCAT1", "BCAT2", "BCR", "BCS1L", "BLM", "BOP1", "BPNT1", "BPTF", "BRCA1", "BRD1", "BRD2", "BRD3", "BRD4", "BUD31", "CAD", "CALR", "CAMSAP3", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CBL", "CBR1", "CBX1", "CBX2", "CBX3", "CBX4", "CBX5", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CD320", "CDC40", "CDH2", "CDKAL1", "CDX2", "CETN2", "CHAF1B", "CHD1", "CHD1L", "CHD4", "CHD5", "CLGN", "CMPK1", "CNDP2", "COLEC12", "COPA", "COPZ1", "COQ5", "CORO1B", "CORO1C", "CORO7", "CPOX", "CRYZ", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CWC27", "CYP51A1", "DBI", "DCAF13", "DCAF7", "DCP2", "DCPS", "DCXR", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX31", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX55", "DDX6", "DHCR7", "DHFR", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX35", "DHX36", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIMT1", "DIS3", "DLG1", "DMD", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB4", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC16", "DNAJC2", "DNAJC21", "DNAJC9", "DNM1", "DNM1L", "DNM2", "DNMBP", "DNMT1", "DPY30", "DRG1", "DRG2", "DSC3", "DSG2", "DST", "DTX3L", "DTYMK", "DUS2", "DUS3L", "DYNLL1", "DYNLL2", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECT2", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EHHADH", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4E", "EIF4E2", "ENO1", "ENO2", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA2", "EPHA7", "EPN1", "EPRS", "EPS15", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FARP1", "FAT1", "FBL", "FCGRT", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FOXC1", "FOXK1", "FOXK2", "FTL", "FUCA1", "FUCA2", "GAA", "GALK1", "GALNS", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GGPS1", "GLA", "GLB1", "GLB1L2", "GLO1", "GMPPA", "GMPPB", "GNPDA1", "GNS", "GOLGA2", "GPHN", "GPI", "GPX8", "GRHPR", "GRWD1", "GSPT1", "GTF2B", "GUF1", "GUSB", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HGS", "HIBADH", "HINT2", "HLA-A", "HLA-B", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMOX1", "HMOX2", "HSD17B10", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IGF1R", "ILVBL", "IMPACT", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "IQGAP1", "IQGAP2", "IQGAP3", "ISCA2", "ITGA2", "ITGAV", "IVD", "KANK2", "KATNA1", "KDM2A", "KDM5A", "KDM5B", "KDSR", "KIF11", "KIF14", "KIF18B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF7", "KIFC1", "LAMP1", "LAMP2", "LARS", "LARS2", "LBR", "LDLR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRP1", "LRP2", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK14", "MAPK3", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME2", "MGA", "MGST2", "MID1", "MIF", "MKRN2", "MOCS1", "MPHOSPH8", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPST", "MRC2", "MRPL13", "MRPL24", "MRPL3", "MRPS11", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "MVK", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS8", "NDUFV1", "NEFL", "NEFM", "NES", "NF1", "NF2", "NID1", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NOTCH2", "NSD1", "NSD2", "NSD3", "NSF", "NUBP2", "NUBPL", "NUDT1", "NUDT12", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL11", "OSBPL1A", "OSBPL2", "OSBPL3", "OSBPL6", "OSBPL8", "OSBPL9", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PAM", "PBRM1", "PCDH7", "PCK2", "PCNA", "PDE8A", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDSS1", "PEBP1", "PEPD", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHF14", "PHF2", "PHF3", "PHF8", "PHGDH", "PHIP", "PI4KA", "PI4KB", "PIK3C2A", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PMS1", "PNP", "PNPLA6", "POLA1", "POLD1", "POLG", "POLR1B", "POLR1C", "POLR2B", "POLR2C", "POLR2E", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL2", "PPIL3", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PRPS1", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PUS7", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "RACK1", "RAE1", "RANBP2", "RARS", "RARS2", "RBBP7", "RCL1", "RDH13", "RDX", "RELA", "RIDA", "RIOK2", "RNF14", "RNF20", "RNF31", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS24", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "RSF1", "RSL24D1", "RTCA", "RTN4IP1", "S100A10", "S100A11", "SART1", "SBDS", "SCAF11", "SCAP", "SCD", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB1", "SERPINB6", "SERPINH1", "SGSH", "SHPRH", "SLC1A5", "SLC27A2", "SLC27A4", "SLC2A1", "SLC4A2", "SLC5A6", "SLIT2", "SMARCA4", "SMG1", "SMU1", "SNRNP40", "SNU13", "SORD", "SORL1", "SPATA5", "SPATA5L1", "SPTBN1", "SPTBN2", "SRCAP", "SRM", "STAM", "STMN1", "STOM", "STX12", "STX18", "STX5", "STX6", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SV2A", "SYNE1", "SYNE2", "TAP1", "TAP2", "TBL3", "TCP1", "TFB1M", "THOC6", "TK1", "TLE3", "TLN1", "TM7SF2", "TMX1", "TMX3", "TMX4", "TOP2A", "TOP2B", "TRAF2", "TRIM21", "TRIM24", "TRIM25", "TRIM28", "TRIM32", "TRIM33", "TRIP13", "TRMT11", "TSFM", "TSPAN3", "TSPAN6", "TST", "TTF2", "TUBB", "TUBB2B", "TUBB4B", "TUBB6", "TUFM", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UBA5", "UBFD1", "UHRF1", "USP10", "USP11", "USP14", "USP19", "USP22", "USP24", "USP28", "USP32", "USP33", "USP34", "USP36", "USP38", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VARS2", "VAT1", "VCL", "VCP", "VIM", "VLDLR", "VPS4A", "VPS4B", "WARS", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR3", "WDR36", "WDR41", "WDR48", "WDR5", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZMYND8"], "leading_proteins": ["ABCB1", "ABCC1", "ABCD4", "ADGRE5", "AP1M1", "AP2M1", "APP", "ARSA", "BAG6", "BCAT2", "CASK", "CD320", "CLGN", "COLEC12", "DLG1", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC2", "DNM1", "DNM1L", "DSC3", "DYNLL1", "EEF1D", "EPHA7", "FAT1", "FCGRT", "FUCA2", "GALNS", "GLB1", "GNS", "HLA-A", "HMGB2", "HMGB3", "HSP90AB1", "HSP90B1", "IDH2", "ITGA2", "LAMP2", "LDLR", "LRP1", "LRP2", "MPP1", "MPP2", "MPP6", "NID1", "NUBPL", "OSBPL1A", "PCDH7", "PLOD1", "PLOD2", "RTN4IP1", "SERPINB1", "SERPINH1", "SLIT2", "SORL1", "STX12", "STX18", "STX6", "SV2A", "TAP2", "TMX4", "TSPAN3", "TUBB", "TUBB2B", "TXNDC12", "TXNL1", "VLDLR", "ZADH2"]}
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{"0": "Immunoglobulin-like domain [IPR007110]", "1": "EGF-like domain [IPR000742]", "2": "Immunoglobulin subtype [IPR003599]", "3": "Immunoglobulin subtype 2 [IPR003598]", "4": "EGF-like calcium-binding domain [IPR001881]", "5": "Fibronectin type III [IPR003961]", "6": "Target SNARE coiled-coil homology domain [IPR000727]", "7": "Immunoglobulin V-set domain [IPR013106]", "8": "P-type ATPase, haloacid dehalogenase domain [IPR044492]", "9": "Immunoglobulin I-set [IPR013098]"}
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interpro_domain/basic/idx2term.json
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{"0": "Immunoglobulin-like domain [IPR007110]", "1": "EGF-like domain [IPR000742]", "2": "Immunoglobulin subtype [IPR003599]", "3": "Immunoglobulin subtype 2 [IPR003598]", "4": "EGF-like calcium-binding domain [IPR001881]", "5": "Fibronectin type III [IPR003961]", "6": "Target SNARE coiled-coil homology domain [IPR000727]", "7": "Immunoglobulin V-set domain [IPR013106]", "8": "P-type ATPase, haloacid dehalogenase domain [IPR044492]", "9": "Immunoglobulin I-set [IPR013098]", "10": "Serine-threonine/tyrosine-protein kinase, catalytic domain [IPR001245]", "11": "Guanylate kinase-like domain [IPR008144]", "12": "Guanylate kinase/L-type calcium channel beta subunit [IPR008145]", "13": "Dynamin, N-terminal [IPR045063]", "14": "Dynamin-type guanine nucleotide-binding (G) domain [IPR030381]", "15": "PDZ domain [IPR001478]", "16": "EF-hand domain [IPR002048]", "17": "Thioredoxin domain [IPR013766]", "18": "Zinc finger, RanBP2-type [IPR001876]", "19": "DnaJ domain [IPR001623]", "20": "Gelsolin-like domain [IPR007123]", "21": "SH3 domain [IPR001452]", "22": "RNA recognition motif domain [IPR000504]", "23": "Zinc finger, LIM-type [IPR001781]"}
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interpro_domain/basic/plot_0.png
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Git LFS Details
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interpro_domain/basic/plot_1.png
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Git LFS Details
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interpro_domain/basic/plot_10.png
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Git LFS Details
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interpro_domain/basic/plot_11.png
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Git LFS Details
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interpro_domain/basic/plot_12.png
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Git LFS Details
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