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Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
Mitochondrial complex iv assembly 0.8325111334211366 2.71635822219948 0.0066004458411039 0.980035391366844 0.2208619422589615 11 P14406,Q9Y2R0,P00403,O43819,P20674,Q7KZN9,P13073 7
Electron transport chain oxphos system in mitochondria 0.5578168407657632 2.385174428295708 0.017071025096105 0.9999619299691022 0.2508273996869314 55 O43676,P00846,O95182,P22695,O96000,O14949,P14406,O95168,P06576,P09669,P00403,O75964,P03886,P20674,Q9UDW1,Q7KZN9,P13073 17
Nephrotic syndrome 0.765215807302299 2.2860016447194123 0.0222541623395151 0.9999983267851916 0.3058653475035688 10 O75844,Q14108 2
Photodynamic therapyinduced nfe2l2 nrf2 survival signaling 0.9259235654327508 2.0498555899653597 0.0403785250116708 0.999999999973632 0.408843841613052 4 P07099,P09601 2
Oxidation by cytochrome p450 0.8119758292585973 2.039279385613798 0.0414221518263981 0.9999999999861392 0.408843841613052 6 O43169,Q6UW02,Q16850 3
Mitochondrial complex i assembly model oxphos system 0.5080398984636076 2.0001617705510855 0.0454827984251728 0.9999999999988722 0.440661210971757 31 O43676,O96000,O95182,O95168,Q96CU9,Q9NPL8,Q8TB37,P03886,Q9Y375,Q9P0J0,O75380 11
Sphingolipid metabolism in senescence 0.6415313296428267 1.973548043819726 0.0484331565050655 0.999999999999819 0.4524964938601792 13 Q06136,Q13510,P16278,Q96G23 4
Sphingolipid metabolism integrated pathway 0.7619011218624283 1.910664303784074 0.0560477349136183 0.9999999999999984 0.4892097682355456 7 O95470,Q13510,Q06136,Q96G23 4
Sphingolipid metabolism overview 0.7619011218624283 1.910664303784074 0.0560477349136183 0.9999999999999984 0.4892097682355456 7 O95470,Q13510,Q06136,Q96G23 4
Statin inhibition of cholesterol production 0.7607613071628377 1.905674694493234 0.056692424445901 0.999999999999999 0.4892097682355456 7 Q14534,P37268,Q8WTV0 3
Familial partial lipodystrophy fpld 0.7572334654391183 1.8902145878480516 0.0587292664532101 0.9999999999999996 0.4958428067692461 7 O75844,O60725,P31751,P20700 4
Sphingolipid pathway 0.7026975626066647 1.8838930024078713 0.0595794499589044 0.9999999999999998 0.4959359848691902 9 O95470,Q13510,Q06136,Q96G23 4
Glycosaminoglycan degradation 0.803965275201333 1.84041350410614 0.0657075523721391 1.0 0.5109626769991343 5 P54802,P16278 2
Cholesterol metabolism with bloch and kandutschrussell pathways 0.5306295473794496 1.8176038847359532 0.0691246974632082 1.0 0.5252838723064378 24 Q9BWD1,Q14534,P37268,Q15392,Q15800,Q16850,O76062 7
Transcriptional activation by nrf2 in response to phytochemicals 0.7902033850154724 1.783424717307742 0.0745171926440835 1.0 0.5381582442331427 5 P09601 1
Influence of laminopathies on wnt signaling 0.7202620591608917 1.726703276913523 0.0842209668569513 1.0 0.5466616498176617 7 O75844,O60725 2
Oxidative phosphorylation 0.4666321028924528 1.6937502640596898 0.0903127486953752 1.0 0.5466616498176617 35 O96000,P00846,O95182,O95168,P06576,O75787,O75964,P03886,O75380,Q86Y39 10
Overlap between signal transduction pathways contributing to lmna laminopathies 0.6041629285089241 1.6696482485096968 0.0949889784127169 1.0 0.567055416585007 12 O75844,P55209,O60725,P50402 4
Striated muscle contraction pathway 0.7222533127838643 1.654387098578448 0.0980488861193047 1.0 0.573588216958772 6 P08670,P28289,P67936 3
Nucleotidebinding oligomerization domain nod pathway 0.7135653581809919 1.616371948064501 0.1060139196142204 1.0 0.5815911681165372 6 Q9P0J0 1
Mitochondrial complex iii assembly 0.6457071315992924 1.6077403361064313 0.1078920604695152 1.0 0.5815911681165372 9 Q6DKK2,Q9UDW1,P22695 3
1q211 copy number variation syndrome 0.6237603032147718 1.5883073508094692 0.1122168561034313 1.0 0.5815911681165372 10 Q9NPH0 1
Ciliopathies 0.5567005913756409 1.574680976596375 0.1153301010112983 1.0 0.5875869801523909 14 Q10713,Q9NVR5,Q13432 3
Triacylglyceride synthesis 0.7293709280470455 1.5283092075228295 0.1264357849122568 1.0 0.607508527505234 5 Q9HCL2 1
Degradation pathway of sphingolipids including diseases 0.6826663436618509 1.4802597399362096 0.1388039430343051 1.0 0.6081916726154011 6 P06280,O43681,P16278 3
Nrf2are regulation 0.6349023934544693 1.4738234535188728 0.1405291318075456 1.0 0.6081916726154011 8 P09601 1
S1p receptor signal transduction 0.6628295713049162 1.4677340099670173 0.1421764886872432 1.0 0.6081916726154011 7 Q13510,P31751 2
Cholesterol biosynthesis with skeletal dysplasias 0.678577438966496 1.462150661344758 0.143699928511773 1.0 0.6081916726154011 6 Q16850 1
Nonalcoholic fatty liver disease 0.452427246135765 1.4607921985904235 0.1440724774385045 1.0 0.6081916726154011 52 O43676,O96000,O95182,P22695,O14949,P14406,O95168,P31751,P00403,P20674,Q9UDW1,Q9P0J0,P13073 13
Progeriaassociated lipodystrophy 0.6151988926620844 1.4570211163921654 0.145110551376959 1.0 0.608229332367254 9 O75844,O60725,P20700 3
Metapathway biotransformation phase i and ii 0.4879875780498665 1.4457850581009828 0.1482374982999814 1.0 0.6088924864232007 22 P07099,Q8NCH0,Q6UW02,Q16850,P78417 5
Urea cycle and related diseases 0.8959948320413444 1.4145194577391302 0.1572094384329552 1.0 0.6088924864232007 2 Q9UJS0 1
Antiviral and antiinflammatory effects of nrf2 on sarscov2 pathway 0.9138234102190606 1.3961176174005574 0.1626790794385275 1.0 0.6088924864232007 3 P09601 1
Ketogenesis and ketolysis 0.6391325985582178 1.3594092460230935 0.1740169428494375 1.0 0.6348395878025779 7 O43772,P53985 2
Copper homeostasis 0.6524076971446396 1.3457997133272026 0.1783671179213288 1.0 0.6456021228320926 6 O75880,O43819,P35670 3
Endothelin pathways 0.631749814348741 1.3255230595879404 0.184997726355562 1.0 0.6534282947462307 7 P16615,P42892 2
Metabolism of spingolipids in er and golgi apparatus 0.8730620155038769 1.323268466761632 0.1857461142425833 1.0 0.6534282947462307 2 Q06136 1
Irinotecan pathway 0.8682170542635526 1.3040262306252997 0.1922246390144024 1.0 0.655359472977567 2 O15118 1
Primary focal segmental glomerulosclerosis fsgs 0.4734203609169732 1.2350907623859035 0.2167967269723822 1.0 0.7099137993313637 16 Q14108 1
7oxoc and 7betahc pathways 0.5523266302779385 1.2181832840425804 0.2231543304466257 1.0 0.7206787393112338 10 O14734,O15118 2
Relationship between inflammation cox2 and egfr 0.8479288275542162 1.156455130283144 0.2474950426358075 1.0 0.7483765536041663 3 Q9H7Z7 1
Mirna regulation of p53 pathway in prostate cancer 0.6973658001616204 1.1486299085632092 0.2507086189271019 1.0 0.7483765536041663 4 O14681,Q13794 2
Translation factors 0.4000753992905944 1.1263818456156698 0.2600039277460555 1.0 0.7609747521294556 33 O75153,P55010 2
Cholesterol biosynthesis pathway 0.5025275171490322 1.096915471703305 0.2726783447317824 1.0 0.7609747521294556 12 Q14534,P37268,Q15800,Q16850 4
Acquired partial lipodystrophy barraquersimons syndrome 0.6826085648374209 1.0897297991179318 0.2758321854946093 1.0 0.7642989511427262 4 O60725,P20700 2
Overview of nanoparticle effects 0.8133074935400328 1.0876464246049766 0.2767512276557418 1.0 0.7642989511427262 2 P09601 1
Sterol regulatory elementbinding proteins srebp signaling 0.3913955138643388 1.059244720434288 0.2894883432072601 1.0 0.7819844565361538 32 P37268,Q16850,Q9HCL2,Q8WTV0 4
Mrna protein and metabolite inducation pathway by cyclosporin a 0.8193938296685086 1.0536095002915935 0.2920617378368939 1.0 0.782390341398626 3 Q14145 1
Head and neck squamous cell carcinoma 0.4776341486382838 1.0216331679565456 0.3069545532572535 1.0 0.7957957429816919 13 P31751 1
Adipogenesis 0.4511678680053934 1.0024515457987082 0.316125557497886 1.0 0.7957957429816919 15 O75844,Q9NR56,P14174,P43490 4
Allograft rejection 0.535887957414112 0.9948949477573588 0.319787360349383 1.0 0.7957957429816919 8 P08670,P08183 2
Camkk2 pathway 0.5196727695170407 0.9770795539685928 0.3285297691043207 1.0 0.7957957429816919 9 P09601 1
Vitamin dsensitive calcium signaling in depression 0.556160858493434 0.9768630997581176 0.3286369321200542 1.0 0.7957957429816919 7 P00390,P20020,P23634 3
Mevalonate arm of cholesterol biosynthesis pathway 0.5195230230024851 0.9763249561432856 0.3289034566184152 1.0 0.7957957429816919 9 P37268,Q9BWD1 2
Eicosanoid metabolism via lipooxygenases lox 0.5697040263959802 0.9758186243563975 0.3291543536787213 1.0 0.7957957429816919 6 O15254 1
Hostpathogen interaction of human coronaviruses apoptosis 0.7774547803617577 0.9492090926955136 0.3425142779164638 1.0 0.7961070138081882 2 Q07812 1
Tp53 network 0.6457701603392239 0.9437037566478018 0.3453210537832585 1.0 0.7961070138081882 4 Q13794 1
Apoptosis modulation and signaling 0.4586530523083905 0.9087713583110214 0.3634708282265784 1.0 0.7961070138081882 13 O95817,Q07812,O43464,O95831,Q13794 5
Prostaglandin and leukotriene metabolism in senescence 0.7655038759689967 0.9038254098382948 0.3660879858069905 1.0 0.7961070138081882 2 P09960 1
Myometrial relaxation and contraction pathways 0.4234158150687671 0.9017715220203886 0.3671782505752614 1.0 0.7961070138081882 16 P78417 1
Cancer immunotherapy by pd1 blockade 0.7512919896640827 0.8504751823215128 0.3950609525942901 1.0 0.8214938020304346 2 P04439 1
Familial hyperlipidemia type 4 0.6184304263359166 0.8368995703508763 0.4026490218976886 1.0 0.8214938020304346 4 Q9UBV2 1
Alzheimers disease and mirna effects 0.3923107871856464 0.8317395438922834 0.4055559749036019 1.0 0.8214938020304346 72 P07437,Q07866,P16615,P28074,P28072,Q9BUF5,Q9NQC3,O95197,P51665,P31751,P49721,P21796,P45880,P28070,Q9BVA1,P20618,Q9Y277 17
Alzheimers disease 0.3868401352839087 0.7784400444274486 0.4363096391882013 1.0 0.822206527464113 71 P07437,Q07866,P16615,P28074,P28072,Q9NQC3,O95197,P51665,P31751,P49721,P21796,P45880,P28070,Q9BVA1,P20618,Q9Y277 16
Folate metabolism 0.4149232045242846 0.7710004638619962 0.4407066566473816 1.0 0.822206527464113 15 Q8NFF5,P41440,Q8WTV0 3
Purinergic signaling 0.7322378056255163 0.7487936600981637 0.4539815815512651 1.0 0.8288746830078851 3 P04899 1
Methionine de novo and salvage pathway 0.4688878806338828 0.723306637719087 0.4694915156806143 1.0 0.8288746830078851 9 Q13126,Q9BV57 2
Nanomaterial induced apoptosis 0.5385954317810897 0.7203774705445232 0.4712926175773115 1.0 0.8288746830078851 5 O95831,O43464 2
Selenium micronutrient network 0.4299882515760962 0.6852399557064668 0.4931925144679501 1.0 0.8311305290309705 12 Q8NFF5,P04114,Q8WTV0 3
P53 transcriptional gene network 0.4459138050117731 0.6634623813234121 0.5070344648766552 1.0 0.8411397895351934 10 Q9NQ88,Q07812,Q13794 3
Metabolic pathway of ldl hdl and tg including diseases 0.5689648212961274 0.6496048851258386 0.5159474767480887 1.0 0.8470137743281122 4 Q8WTV0 1
Complement system in neuronal development and plasticity 0.4572806735758614 0.6195062811735266 0.5355828853170612 1.0 0.8645001968487889 8 Q5KU26,O43464 2
Heme biosynthesis 0.5588897200349536 0.6127740207566289 0.5400257709914762 1.0 0.8649193242709009 4 P22830 1
Dna damage response 0.3691861228685488 0.5830837463847923 0.559836924832541 1.0 0.8786571432600234 22 P14635,Q13794,P41440,Q9BXW9 4
Modulators of tcr signaling and t cell activation 0.4361184959817771 0.564297687117801 0.572551555219412 1.0 0.8803273778589846 9 O96000 1
Proteoglycan biosynthesis 0.4984973615759738 0.5607492709822012 0.5749684735254958 1.0 0.8803273778589846 5 Q8NCH0 1
Ferroptosis 0.3619273269466833 0.5318463788910963 0.594832397756492 1.0 0.896297231003801 22 P16435,P37268,P09601,P45880,Q9Y277 5
Male infertility 0.3645976910412947 0.5248872811348719 0.5996615516379715 1.0 0.896297231003801 19 P08183,Q15165 2
G protein signaling pathways 0.3878858939174363 0.4980687908187511 0.6184355569263087 1.0 0.896297231003801 13 O43823,P04899,Q92667,P63218,Q14344 5
Mirna regulation of dna damage response 0.3548683284132145 0.4941921898586555 0.6211704550116988 1.0 0.897583713721061 23 P14635,Q13794,P41440,Q9BXW9 4
Joubert syndrome 0.3605114916692719 0.4915559837360387 0.6230332663228362 1.0 0.898079659504381 16 Q13432,P41208 2
Dna mismatch repair 0.3573713303201127 0.4771047500764501 0.6332875323840472 1.0 0.8983804010888795 19 Q9UQ84,P41440 2
Nuclear receptors metapathway 0.342863101080038 0.4679334019698281 0.6398322161068981 1.0 0.8983804010888795 49 P09601,Q9HCL2,P08183,P27105,Q14145 5
Mitochondrial long chain fatty acid betaoxidation 0.3639244909758702 0.4558258671961036 0.6485152015217266 1.0 0.8983804010888795 15 O43772,P23786 2
H19 action rbe2f1 signaling and cdkbetacatenin activity 0.4688758067123436 0.4494467957260072 0.6531093803228936 1.0 0.8983804010888795 5 Q15648,P11802,Q13794 3
Glycerophospholipid biosynthetic pathway 0.4020746649584875 0.4466210558917602 0.655148690088974 1.0 0.8983804010888795 10 Q9HCL2 1
Vitamin d receptor pathway 0.3752426091740149 0.4284553946939639 0.6683196018730366 1.0 0.8983804010888795 13 P08183,Q5VV42 2
Nad metabolism sirtuins and aging 0.6095011814551018 0.3737249566710528 0.7086089558489652 1.0 0.9120265486365866 3 P43490 1
Ccl18 signaling pathway 0.373142927741361 0.3421541329869401 0.7322349008566338 1.0 0.9306469385081088 11 P08670,P07196 2
Genes related to primary cilium development based on crispr 0.3860205381528278 0.3366106158321153 0.7364104525060704 1.0 0.931680290378362 9 Q96J42,Q10713,Q9C0F1 3
Phosphoinositides metabolism 0.4036050631268232 0.2906917562174111 0.7712870770584761 1.0 0.955619837613332 6 Q8TBX8 1
Synaptic signaling pathways associated with autism spectrum disorder 0.3735054763536465 0.2598820802956398 0.7949547343283927 1.0 0.9593842420344626 8 P31751 1
Cytosolic dnasensing pathway 0.3667853674328105 0.2568181576846799 0.7973191522846419 1.0 0.9593842420344626 9 Q9NZI8,Q7Z434,P19388,O14802,O15160,Q14258,P62875,P55265 8
Histone modifications 0.3597686921408722 0.2555273637393185 0.798315811708223 1.0 0.9593842420344626 10 Q15047 1
Thermogenesis 0.3114022072540334 0.2432646594710439 0.8078003798235582 1.0 0.9593842420344626 27 O43772,P23786 2
Tyrobp causal network in microglia 0.4362333648324441 0.227975698571494 0.8196651328242148 1.0 0.9630657922447534 4 Q15758 1
Ethanol effects on histone modifications 0.3438409188796852 0.210142455704884 0.8335564903350647 1.0 0.9678426046915978 11 Q9H9T3,P41440,P00374 3
Amyotrophic lateral sclerosis als 0.357887428906216 0.2021230451651965 0.8398205322281476 1.0 0.9698728800487804 8 P07196,Q07812,P07197 3
Type i collagen synthesis in the context of osteogenesis imperfecta 0.3400866515290462 0.194307322463152 0.8459352524079213 1.0 0.9698728800487804 11 O75718,Q32P28 2
Novel intracellular components of rigilike receptor rlr pathway 0.3665480427046197 0.186162691226858 0.8523171805650465 1.0 0.970557714285053 7 Q7Z434,Q92841,O00571,Q13573,Q13526,Q14258 6
Genes controlling nephrogenesis 0.3698370220650329 0.1817570428179795 0.8557733977664197 1.0 0.9719440927148844 6 O94813 1
Hepatitis c and hepatocellular carcinoma 0.3646069233257732 0.179900448128788 0.8572307233856205 1.0 0.9719440927148844 7 P40763,Q14247,P63000,P31350,P62993,P38398 6
Development of ureteric collection system 0.378788321799425 0.1674342329263229 0.8670283913662928 1.0 0.9741706830750552 5 O94813 1
Nucleotide excision repair 0.3040022264758231 0.15061639123957 0.8802783305637509 1.0 0.9806114881936434 21 P41440,P41208 2
Proteasome degradation 0.2927293963019465 0.1364191075894604 0.8914899692121643 1.0 0.988500134717428 39 O00231,P28074,P28072,Q9UL46,P51665,P10321,P49721,P28070,P20618,P04843 10
Mammary gland development pathway involution stage 4 of 4 0.4897469856213082 0.1289054309634341 0.8974324792394504 1.0 0.9913693368794676 3 Q07812 1
Nsp1 from sarscov2 inhibits translation initiation in the host cell 0.3133149469437077 0.1231864665481664 0.901959442072482 1.0 0.9928660462210182 13 O00303,O15372,P55010 3
Autosomal recessive osteopetrosis pathways 0.4764211886304902 0.1211364094394986 0.9035829909478352 1.0 0.9928660462210182 2 P51798 1
Regulation of apoptosis by parathyroid hormonerelated protein 0.3752264640562316 0.1015498688348071 0.9191139725208132 1.0 0.9985227164702218 4 Q9BXK5,Q07812 2
Factors and pathways affecting insulinlike growth factor igf1akt signaling 0.3462657613966944 0.0940859354529898 0.9250408927009566 1.0 0.999579667812348 5 Q13418,Q15118,P06730,P42345 4
Hedgehog signaling pathway wp47 0.4127906976744201 0.070049021121155 0.9441546422202312 1.0 1.0 2 O00422 1
Microrna network associated with chronic lymphocytic leukemia 0.3640180878552974 0.0530277038172763 0.9577098343071038 1.0 1.0 2 Q07820 1
Mammary gland development pathway embryonic development stage 1 of 4 0.3459302325581372 0.0497889457771561 0.960290575750694 1.0 1.0 2 O60315 1
Complement and coagulation cascades 0.345284237726095 0.0496953109279573 0.9603651931818864 1.0 1.0 2 P49257 1
Mecp2 and associated rett syndrome 0.2847929146312163 0.0463039209746773 0.9630680141774356 1.0 1.0 21 Q03518,P52597,Q05086,P67809,P31943,Q00013 6
Endometrial cancer 0.2964798013146552 0.0328737669770905 0.9737752524052156 1.0 1.0 11 Q07812,P35222,P35221,P31751,Q13418 5
Cellular proteostasis 0.3071066385897544 0.0215742584713907 0.9827875675157796 1.0 1.0 4 O60925 1
Interactions between loxl4 and oxidative stress pathway 0.3295638126009714 0.0211366353712046 0.9831366606161605 1.0 1.0 3 Q9BQ95,Q16543 2
Ptf1a related regulatory pathway 0.2969305331179334 0.0174020943260819 0.9861158383785784 1.0 1.0 3 P35222,Q06330 2
Chemokine signaling pathway 0.2758115562769337 0.0149989117821175 0.9880330485574548 1.0 1.0 18 P63218,P04899,P31751,P63096 4
Calcium regulation in cardiac cells 0.2773419466303138 0.0080849782786039 0.9935491909353557 1.0 1.0 23 P04899,P16615,P08133,P63218,P20020,P63096,P23634 7
3q29 copy number variation syndrome 0.2920439844760617 0.0037111899999854 0.9970389055939656 1.0 1.0 6 Q09161,P02786,Q96FJ2,P61088,P52298 5