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interpro_active_site/advanced/idx2term.json

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+{}

interpro_active_site/basic/idx2term.json

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+{}

interpro_active_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:02131b116f82e6e807c05289b7aae5bdaca5e1fde0e4a938cf7867e1bfc00813
+size 77969

interpro_active_site/df_merge.tsv

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+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_active_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3098,
+    "annotations_size": 56,
+    "title": "Average number of proteins per term",
+    "value": 2.375
+}

interpro_active_site/paths.json

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+{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C177/C177_val_log2fc"}

interpro_active_site/result.tsv

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+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Histidine acid phosphatase active site [IPR033379]	0.9625322997415984	1.679592201764284	0.0930366859860589	0.995782798526063	0.1929649783414556	2	Q9NPH0	1
+Serine carboxypeptidase, serine active site [IPR018202]	0.8400646203554267	1.128023075105343	0.25931017410517	0.999999949923123	0.4400415075724097	3	Q9HB40,Q9H3G5	2
+ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]	0.4379200563021249	0.2321943072233575	0.8163870991235236	1.0	0.8625976896399494	4	P06576	1

interpro_active_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["ATP synthase, F0 complex, subunit A, active site [IPR023011]", "ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenylosuccinate synthase,  active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Coenzyme A transferase active site [IPR004164]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "DNA topoisomerase, type IA, active site [IPR023406]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glutaredoxin active site [IPR011767]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Lipase, GDXG, putative serine active site [IPR033140]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine proteases, trypsin family, histidine active site [IPR018114]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]"], "available_proteins": ["ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADSS", "AKT2", "APEH", "ATP5A1", "ATP5B", "ATP6", "ATP6V1A", "ATP6V1B2", "AURKA", "AURKB", "BLMH", "CAMK2G", "CAPN1", "CAPN2", "CDC34", "CDK1", "CDK2", "CDK4", "CDK5", "CDK9", "CHEK1", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CTSA", "CTSC", "DLD", "DNMT1", "DUSP11", "DUSP3", "EIF2AK2", "EPHA7", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLRX", "GLUD1", "GSR", "HADHB", "HMGCL", "HMGCS1", "LDHA", "LDHB", "LONP1", "LYN", "MAPK1", "MDH1", "MDH2", "MTMR2", "NCEH1", "NEK9", "NME1", "NME6", "OXCT1", "PBK", "PGAM1", "PIK3R4", "PKM", "PKMYT1", "PKN1", "PKN2", "PLK1", "PREP", "PRKAA1", "PRKAA2", "PRKCA", "PRKCB", "PRPF4B", "PRSS3", "PTK7", "PTPMT1", "PTPN1", "PTPN9", "RIPK1", "RNASET2", "RPS6KA1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SRPK2", "SUCLG1", "TALDO1", "TIGAR", "TOP1", "TOP3A", "TPI1", "TPP2", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "UMPS", "VRK1", "VRK2", "YES1"], "leading_proteins": ["ACP6", "ATP5B", "CPVL", "SCPEP1"]}

interpro_binding_site/advanced/idx2term.json

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+{}

interpro_binding_site/basic/idx2term.json

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+{"0": "EF-Hand 1, calcium-binding site [IPR018247]"}

interpro_binding_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:bfcd0958b0b44b340ef332f64fe597613c268346d50e0f16f334b8cfe31242ae
+size 71234

interpro_binding_site/df_merge.tsv

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+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_binding_site/metrics.json

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+{
+    "type_of_task": "ranksum",
+    "signature_size": 3098,
+    "annotations_size": 29,
+    "title": "Average number of proteins per term",
+    "value": 4.275862068965517
+}

interpro_binding_site/paths.json

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+{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C177/C177_val_log2fc"}

interpro_binding_site/result.tsv

@@ -0,0 +1,4 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Peptidase M16, zinc-binding site [IPR001431]	0.6455060247964413	1.170774229144595	0.2416895391702949	0.9996722336495591	0.4331678136194573	5	Q10713,P22695	2
+Beta tubulin, autoregulation binding site [IPR013838]	0.8436187399030685	1.1408653522521912	0.2539259597079577	0.9997955081804496	0.4331678136194573	3	P07437,Q9BVA1	2
+EF-Hand 1, calcium-binding site [IPR018247]	0.3403469902613198	0.5627599766612554	0.5735983373296456	0.9999999999816028	0.6653740713023889	36	Q02818,O95202,P80303,Q14257,Q9BRK5,P41208,O95302,Q9NWM8	8

interpro_binding_site/selections.json

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+{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Coenzyme A transferase binding site [IPR004163]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]", "Ureohydrolase, manganese-binding site [IPR020855]"], "available_proteins": ["ACACA", "ACO2", "ACTN1", "ACTN4", "ADSS", "AKT2", "APEX1", "ARG2", "AURKA", "AURKB", "CALU", "CAMK2G", "CAPN1", "CAPN2", "CDK1", "CDK2", "CDK4", "CDK5", "CDK9", "CETN2", "CHEK1", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CYB5B", "DBT", "DLAT", "DLST", "DST", "EHD1", "EHD4", "EIF2AK2", "EPHA7", "EPS15", "FKBP10", "FKBP14", "FKBP9", "GCAT", "GOT1", "GOT2", "GPD2", "HK1", "HK2", "IDE", "ILKAP", "IQGAP1", "IQGAP2", "LETM1", "LPCAT2", "LYN", "MACF1", "MAPK1", "MCCC1", "MICU1", "MYH10", "MYH9", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "NFS1", "NRDC", "NUCB1", "NUCB2", "OXCT1", "PA2G4", "PAK4", "PC", "PCCA", "PDCD6", "PDHX", "PEF1", "PGD", "PKMYT1", "PKN1", "PKN2", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1G", "PRKAA1", "PRKAA2", "PRKCA", "PRKCB", "PRKCSH", "PSAT1", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "RPS6KA1", "RPS6KA3", "S100A11", "SDF4", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "SRPK2", "STK26", "TKT", "TUBB", "TUBB2B", "TUBB6", "UBE3C", "UQCRC2", "VRK1", "YES1"], "leading_proteins": ["CETN2", "FKBP14", "FKBP9", "LETM1", "NUCB1", "NUCB2", "PMPCA", "RCN2", "SDF4", "TUBB", "TUBB2B", "UQCRC2"]}

interpro_conserved_site/advanced/idx2term.json

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+{}

interpro_conserved_site/basic/idx2term.json

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+{"0": "Syntaxin/epimorphin, conserved site [IPR006012]", "1": "Proteasome beta-type subunit, conserved site [IPR016050]", "2": "ABC transporter-like, conserved site [IPR017871]"}

interpro_conserved_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:b0554617a84bb16c5547cc155885808fb4f7521a33122d6de253abc7f900d2ae
+size 94729

interpro_conserved_site/df_merge.tsv

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+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_conserved_site/metrics.json

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+{
+    "type_of_task": "ranksum",
+    "signature_size": 3098,
+    "annotations_size": 277,
+    "title": "Average number of proteins per term",
+    "value": 2.6823104693140793
+}

interpro_conserved_site/paths.json

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+{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C177/C177_val_log2fc"}

interpro_conserved_site/result.tsv

@@ -0,0 +1,18 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Syntaxin/epimorphin, conserved site [IPR006012]	0.7591446973848249	1.898593345718718	0.0576179640061265	0.9999999274096848	0.2280025147099577	7	O43752,O15400,Q13277,Q9P2W9,O60499	5
+Haem oxygenase conserved site [IPR018207]	0.9757751937984468	1.732204000597203	0.0832372470036126	0.9999999999649104	0.2900241182447184	2	P30519	1
+Proteasome beta-type subunit, conserved site [IPR016050]	0.6800940016086875	1.688106957380287	0.0913906991549711	0.9999999999970456	0.2978261607756117	8	P28074,P28072,P49721,P28070,P20618	5
+ABC transporter-like, conserved site [IPR017871]	0.6021504808539841	1.6585367630484638	0.0972091736004534	0.9999999999995016	0.2998305907682788	12	Q03518,O14678,P08183,P33527,O75027	5
+Thioredoxin, conserved site [IPR017937]	0.5998736681083771	1.548880483158928	0.12141045341217	0.9999999999999998	0.3085384916988175	11	Q8IXB1,Q9H1E5	2
+Tetraspanin, conserved site [IPR018503]	0.9192506459948232	1.5072088176986629	0.1317571407881947	1.0	0.3243648938520267	2	O60637	1
+Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]	0.928583856161466	1.4499247473571135	0.1470795054014719	1.0	0.3245875917582254	3	Q8N4Q0	1
+C-type lectin, conserved site [IPR018378]	0.863372093023243	1.2848007967693271	0.198861903877912	1.0	0.3889065546905323	2	Q5KU26	1
+Intermediate filament protein, conserved site [IPR018039]	0.5737403892714299	1.1787656205384622	0.2384915176071125	1.0	0.4494023835181644	8	P08670,P07196,P20700	3
+Tubulin, conserved site [IPR017975]	0.8436187399030685	1.1408653522521912	0.2539259597079577	1.0	0.4720636969067402	3	P07437,Q9BVA1	2
+Heavy-metal-associated, conserved site [IPR017969]	0.7729328165374701	0.931985043672298	0.3513442548847139	1.0	0.5724844623709751	2	P35670	1
+Guanylate kinase, conserved site [IPR020590]	0.4420980702300843	0.2428011249188632	0.8081594640855625	1.0	0.8954406862068033	4	Q9NZW5	1
+Aldehyde dehydrogenase, cysteine active site [IPR016160]	0.3428328567513051	0.1140232154897451	0.909219390162152	1.0	0.9724083825286338	7	P51648	1
+Ribosomal protein L24e, conserved site [IPR023442]	0.4463824289405695	0.0920173335635597	0.9266842678267944	1.0	0.9872751622616232	2	Q9UHA3	1
+Clathrin adaptor, mu subunit, conserved site [IPR018240]	0.4481421647818978	0.0798732856599932	0.936338036884262	1.0	0.9937380697967072	3	Q9BXS5,Q9Y2T2	2
+DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]	0.3779069767441838	0.0564707970197855	0.9549667589919276	1.0	0.9947579917550416	2	O15160	1
+Heat shock protein Hsp90, conserved site [IPR019805]	0.406462035541178	0.0477960911146797	0.9618787518364572	1.0	0.9947579917550416	3	P08238,P07900	2

interpro_conserved_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Aminotransferase, class IV, conserved site [IPR018300]", "Amyloidogenic glycoprotein,  copper-binding domain conserved site [IPR019744]", "Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]", "Anion exchange, conserved site [IPR018241]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Band 7/stomatin-like, conserved site [IPR018080]", "Bax inhibitor 1, conserved site [IPR006213]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "CBX family C-terminal motif [IPR033773]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific,  conserved site [IPR031303]", "DNA mismatch repair, conserved site [IPR014762]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Endonuclease III-like, conserved site-2 [IPR004036]", "Endonuclease III-like, iron-sulphur cluster loop motif [IPR003651]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Ependymin, conserved site [IPR018224]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "Ferritin, conserved site [IPR014034]", "Fibrillarin, conserved site [IPR020813]", "Fork head domain conserved site 2 [IPR030456]", "Fork head domain conserved site1 [IPR018122]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glutathione peroxidase conserved site [IPR029760]", "Glycerate/sugar phosphate transporter, conserved site [IPR021159]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Heavy-metal-associated, conserved site [IPR017969]", "Helix-hairpin-helix motif [IPR000445]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "Homeobox, conserved site [IPR017970]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Integrin alpha chain, C-terminal cytoplasmic region, conserved site [IPR018184]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "MoaA/NifB/PqqE, iron-sulphur binding, conserved site [IPR000385]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NADH:ubiquinone oxidoreductase, subunit 1, conserved site [IPR018086]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site [IPR023058]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P,  conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S14, conserved site [IPR018271]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium/solute symporter, conserved site [IPR018212]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinate dehydrogenase, cytochrome b subunit, conserved site [IPR018495]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Transcription factor TFIIB, conserved site [IPR023486]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Tubulin, conserved site [IPR017975]", "Tyrosine-protein kinase, receptor class V, conserved site [IPR001426]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]", "tRNA-dihydrouridine synthase, conserved site [IPR018517]"], "available_proteins": ["AAAS", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACSS1", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK2", "AK3", "AK4", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1M1", "AP1S2", "AP2M1", "AP2S1", "AP3M1", "APEX1", "APLP2", "ATAD1", "ATAD2", "ATP5C1", "ATP5O", "ATP7A", "ATP7B", "BAG6", "BAK1", "BARD1", "BAX", "BAZ1A", "BAZ1B", "BCAT2", "BCS1L", "BLM", "BMI1", "BOP1", "BPTF", "BRCA1", "BRD1", "BRD2", "BRD3", "BRD4", "BUD31", "CAD", "CALR", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CBR1", "CBR4", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDC40", "CDH2", "CDKAL1", "CECR2", "CETN2", "CHAF1B", "CHD1", "CHD1L", "CHD4", "CLGN", "CMPK1", "CNDP2", "COLEC12", "COPA", "COPZ1", "CORO1C", "CPOX", "CRYZ", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CYP51A1", "DCAF13", "DCAF7", "DCPS", "DCXR", "DDT", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX31", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX55", "DDX6", "DHCR7", "DHFR", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX30", "DHX36", "DHX38", "DHX57", "DHX8", "DHX9", "DIDO1", "DIMT1", "DIS3", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DRG1", "DRG2", "DSC1", "DSC3", "DSG2", "DST", "DTYMK", "DUS2", "DYNLL1", "DYNLL2", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EHHADH", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4E", "ENO1", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPRS", "EPS15", "ETFA", "ETFB", "EXO1", "EZR", "FARP1", "FBL", "FCGRT", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FOXK1", "FTL", "FUCA1", "FUCA2", "GAA", "GALK1", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GFM2", "GLA", "GLB1", "GLB1L2", "GLO1", "GNPDA1", "GNS", "GPI", "GPX8", "GRHPR", "GRWD1", "GSPT1", "GTF2B", "GTF3C2", "GUF1", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HIBADH", "HINT2", "HLA-A", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMOX1", "HMOX2", "HOXD11", "HSD17B10", "HSD17B12", "HSD17B4", "HSD17B8", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "ILVBL", "IMPAD1", "IMPDH2", "INA", "ING5", "IQGAP1", "IQGAP2", "ITGAV", "IVD", "KDM2A", "KDSR", "KIF11", "KIF18B", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFC1", "LAMP1", "LAMP2", "LARS", "LARS2", "LBR", "LDLR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRWD1", "LSS", "MACF1", "MAPK1", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME1", "ME2", "MGST2", "MID1", "MIF", "MKRN2", "MOCS1", "MPHOSPH8", "MPI", "MPP1", "MPP6", "MPP7", "MPST", "MRC2", "MRPL3", "MRPS11", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "ND1", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS8", "NDUFV1", "NEFL", "NEFM", "NES", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NSD1", "NSD2", "NSD3", "NSF", "NTHL1", "NUBP1", "NUBPL", "NUDT1", "NUDT12", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL6", "OSBPL8", "OSBPL9", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PBRM1", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA6", "PEBP1", "PEPD", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PHF2", "PHF3", "PHGDH", "PHIP", "PHRF1", "PI4KA", "PIK3C2A", "PIN1", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PNP", "PNPLA6", "POLA1", "POLD1", "POLR1B", "POLR1C", "POLR2B", "POLR2C", "POLR2E", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL3", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "RACK1", "RAE1", "RANBP2", "RARS", "RARS2", "RBBP7", "RCL1", "RDH13", "RDX", "RIDA", "RNF2", "RNF20", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS24", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "RSF1", "RSL24D1", "S100A10", "S100A11", "SART1", "SBDS", "SCAF11", "SCD", "SCP2", "SDHB", "SDHC", "SEC11A", "SEC61A1", "SERPINB6", "SERPINH1", "SLC1A5", "SLC25A42", "SLC27A2", "SLC27A4", "SLC2A1", "SLC37A4", "SLC4A2", "SLC5A6", "SLIT2", "SMARCA4", "SMU1", "SNRNP40", "SNU13", "SORD", "SPATA5", "SPTBN1", "SPTBN2", "SRCAP", "SRM", "STMN1", "STOM", "STRN", "STRN4", "STX10", "STX12", "STX18", "STX3", "STX5", "STX6", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SYNE2", "TAP1", "TAP2", "TBL1XR1", "TBL3", "TCP1", "TFB1M", "THOC6", "TK1", "TLE3", "TLN1", "TM7SF2", "TMBIM6", "TMX1", "TMX3", "TMX4", "TOP2A", "TOP2B", "TRIM24", "TRIM25", "TRIM27", "TRIM28", "TRIM33", "TRIM4", "TRIP13", "TSFM", "TSPAN3", "TSPAN6", "TST", "TUBB", "TUBB2B", "TUBB6", "TUFM", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UBFD1", "UHRF1", "USP10", "USP14", "USP19", "USP36", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VARS2", "VAT1", "VCL", "VCP", "VIM", "VPS4A", "WARS", "WARS2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR36", "WDR41", "WDR5", "WDR61", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZMYND8"], "leading_proteins": ["ABCB1", "ABCB7", "ABCC1", "ABCD4", "ALDH3A2", "AP1M1", "AP3M1", "ATP7B", "COLEC12", "DNAJC10", "HMOX2", "HSP90AA1", "HSP90AB1", "LMNB1", "MPP6", "NEFL", "POLR1C", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMB6", "RSL24D1", "STX10", "STX18", "STX3", "STX6", "STX7", "TAP1", "TMX4", "TSPAN3", "TUBB", "TUBB2B", "VIM", "ZADH2"]}

interpro_domain/advanced/idx2term.json

@@ -0,0 +1 @@
+{}

interpro_domain/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Target SNARE coiled-coil homology domain [IPR000727]", "1": "P-type ATPase, haloacid dehalogenase domain [IPR044492]", "2": "ABC transporter type 1, transmembrane domain [IPR011527]", "3": "ABC transporter-like, ATP-binding domain [IPR003439]", "4": "Band 7 domain [IPR001107]", "5": "Dynamin, N-terminal [IPR045063]", "6": "Dynamin-type guanine nucleotide-binding (G) domain [IPR030381]", "7": "EF-hand domain [IPR002048]", "8": "K Homology domain, type 1 [IPR004088]", "9": "TOG domain [IPR034085]", "10": "SWAP/Surp [IPR000061]", "11": "PDZ domain [IPR001478]"}

interpro_domain/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:92b15f0f7f64efcc7455713c1ca813b2437c10fb7eeba18aa031a7fb714446ad
+size 322182

interpro_domain/df_merge.tsv

@@ -0,0 +1,5 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+Cytochrome b5-like heme/steroid binding domain [IPR001199]	3	6	2.3897370946713883	0.0168604372934824	2.813106796116505	6.104368932038835	1.6405397264547834	0.1100883340733615	1.2852875686886795	0.8042848477475721	1.100790504333474	0.1612592696854457	3.811917339060444e-05	0.0014481500629001	0.0001833288791406	0.000142755965642	0.0019884945269669
+Glutathione S-transferase, N-terminal [IPR004045]	1	8	2.2834458860600946	0.0224041169788014	2.4635922330097086	7.354368932038835	0.1379245375050955	0.5007649291980636	1.692684060559357	0.9479949918991396	0.9964823876403148	0.2990443112345751	0.0147099496631327	0.0012105019492812	0.0048484802924912	0.027832231049335	0.0968157430558884
+Glutathione S-transferase, C-terminal-like [IPR010987]	1	11	2.036007480931588	0.041749604075012	3.949029126213592	11.37621359223301	-0.0908035435769439	0.5323098181486043	2.6346872162188446	1.2313530457632356	0.9588413776865506	0.2992576122582335	0.0303360476395803	0.0026008925831016	0.0102498345034834	0.0561137872346343	0.1807018090276839
+Polyketide synthase, enoylreductase domain [IPR020843]	1	5	2.0272227019791127	0.0426396424699231	1.6189320388349515	6.283980582524272	0.4837477775906041	0.3583565743712875	1.2357658783365448	1.1656223303878015	1.2317099658487027	0.2921137785685181	0.0147099496631327	1.0	0.1018169846714528	0.027832231049335	0.0968157430558884

interpro_domain/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3098,
+    "annotations_size": 2495,
+    "title": "Average number of proteins per term",
+    "value": 2.171142284569138
+}

interpro_domain/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C177/C177_val_log2fc"}

interpro_domain/result.tsv

@@ -0,0 +1,208 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Cytochrome b5-like heme/steroid binding domain [IPR001199]	0.8969836854872061	2.3897370946713883	0.0168604372934824	1.0	0.1208815834690764	6	Q9UMX5,O43169,Q8WUJ1	3
+Glutathione S-transferase, N-terminal [IPR004045]	0.8109072229825439	2.2834458860600946	0.0224041169788014	1.0	0.1355594432261878	8	Q9H7Z7	1
+Glutathione S-transferase, C-terminal-like [IPR010987]	0.6932167133693996	2.0360074809315876	0.041749604075012	1.0	0.1799054614285925	11	Q9H7Z7	1
+Polyketide synthase, enoylreductase domain [IPR020843]	0.8495989136466542	2.0272227019791127	0.0426396424699231	1.0	0.1827936562928835	5	Q8N4Q0	1
+Target SNARE coiled-coil homology domain [IPR000727]	0.7170544907899895	1.9522444565384327	0.0509091883747767	1.0	0.2022586385271783	9	O43752,O15400,Q13277,O60499,Q9UNK0	5
+Major facilitator superfamily domain [IPR020846]	0.781471628614007	1.9100823274275105	0.0561226140579345	1.0	0.2150935822957705	6	P53985,Q8NHS3,Q9H2V7	3
+P-type ATPase, haloacid dehalogenase domain [IPR044492]	0.7049311463738145	1.894560041419152	0.0581507128361031	1.0	0.2188326222112782	9	Q04656,P16615,P98194,Q9HD20,P35670,P20020,P23634	7
+ABC transporter type 1, transmembrane domain [IPR011527]	0.6960340857549782	1.8519977584906195	0.0640261447835532	1.0	0.23069110504081	9	Q03518,O14678,P08183,P33527,O75027	5
+Sterile alpha motif domain [IPR001660]	0.7480734536598245	1.8499549939435809	0.0643200365728788	1.0	0.2312370190912576	7	Q15375,Q13586	2
+LEM domain [IPR003887]	0.7460473978188771	1.7578670224234323	0.0787701381340229	1.0	0.2627167738661094	6	Q86XL3,P50402	2
+Aminopeptidase N-like , N-terminal domain [IPR045357]	0.7786366931692127	1.7353059191754268	0.0826866338861762	1.0	0.2707591662839105	5	P55786,Q9UIQ6,Q9NZ08	3
+Peptidase M1, membrane alanine aminopeptidase [IPR014782]	0.7786366931692127	1.7353059191754268	0.0826866338861762	1.0	0.2707591662839105	5	P55786,Q9UIQ6,Q9NZ08	3
+Alcohol dehydrogenase, N-terminal [IPR013154]	0.7704420683021054	1.7010979162749131	0.0889246021399925	1.0	0.2822733872001035	5	Q8N4Q0	1
+Reticulon [IPR003388]	0.8274078862314163	1.6671027731892498	0.0954939708150015	1.0	0.2887963243398979	4	Q9NQC3,O95197,O75298	3
+Cation-transporting P-type ATPase, N-terminal [IPR004014]	0.7620433236340269	1.6659404564179647	0.09572527464092	1.0	0.2887963243398979	5	P98194,P20020,P16615,P23634	4
+Cation-transporting P-type ATPase, C-terminal [IPR006068]	0.7620433236340269	1.6659404564179647	0.09572527464092	1.0	0.2887963243398979	5	P98194,P20020,P16615,P23634	4
+ABC transporter-like, ATP-binding domain [IPR003439]	0.6021504808539841	1.6585367630484638	0.0972091736004534	1.0	0.2922131182326883	12	Q03518,O14678,P08183,P33527,O75027	5
+TRAM/LAG1/CLN8 homology domain [IPR006634]	0.8199642856976035	1.6377157555678998	0.1014810023626409	1.0	0.2985791284136663	4	Q96CP7,Q96G23	2
+GOLD domain [IPR009038]	0.659842211459019	1.5925593675258976	0.1112590749263782	1.0	0.312955346044322	8	Q15363,Q9H3P7,Q9Y3B3	3
+Prenylcysteine lyase [IPR010795]	0.9360465116279038	1.5741551213958738	0.1154515918014289	1.0	0.3179378824995201	2	Q9UHG3	1
+Marvel domain [IPR008253]	0.934431524547804	1.567719642154324	0.1169465755915819	1.0	0.3213454913006575	2	O43760	1
+GMP phosphodiesterase, delta subunit [IPR008015]	0.933139534883718	1.562570910628414	0.1181535548519736	1.0	0.3243048617774194	2	A6NIH7	1
+BAG domain [IPR003103]	0.800407434523022	1.5602522330945376	0.1187002865553932	1.0	0.3254474889623144	4	O95817,Q9UL15	2
+Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain [IPR019564]	0.9292635658914672	1.547123096779732	0.1218335654583904	1.0	0.3280418436547405	2	Q13505	1
+Metaxin, glutathione S-transferase domain [IPR033468]	0.9292635658914672	1.547123096779732	0.1218335654583904	1.0	0.3280418436547405	2	Q13505	1
+Syntaxin 6, N-terminal [IPR015260]	0.9173126614987084	1.499482921888743	0.1337483959162941	1.0	0.3461641574804502	2	O60499	1
+ERAP1-like C-terminal domain [IPR024571]	0.9350565428109848	1.473512461634797	0.1406129061548973	1.0	0.3558105485359724	3	P55786,Q9UIQ6	2
+Phospholipid/glycerol acyltransferase [IPR002123]	0.6111424066899058	1.436849266292248	0.1507608281902226	1.0	0.3692227583332823	9	Q9HCL2	1
+GINS subunit, domain A [IPR021151]	0.8924418604651168	1.4003678148940517	0.161403202840157	1.0	0.3845033310862072	2	Q9BRX5	1
+Choline/carnitine acyltransferase domain [IPR039551]	0.8879198966408282	1.3823627897839132	0.1668603353918549	1.0	0.3934938911178432	2	P23786	1
+Cysteine-rich flanking region, C-terminal [IPR000483]	0.8821059431524467	1.3592256528914348	0.1740750947610689	1.0	0.4036406704729248	2	Q13641	1
+Leucine-rich repeat N-terminal domain [IPR000372]	0.8821059431524467	1.3592256528914348	0.1740750947610689	1.0	0.4036406704729248	2	Q13641	1
+Glycosyltransferase 2-like [IPR001173]	0.7458952994859267	1.3428475361091792	0.1793213473689086	1.0	0.4112194500785174	4	O60762	1
+BTB/Kelch-associated [IPR011705]	0.8717700258397851	1.3181356712664063	0.1874582352008236	1.0	0.4248031760454631	2	Q14145	1
+C-type lectin-like [IPR001304]	0.863372093023243	1.2848007967693271	0.198861903877912	1.0	0.4371457710796392	2	Q5KU26	1
+CD209-like, C-type lectin-like domain [IPR033989]	0.863372093023243	1.2848007967693271	0.198861903877912	1.0	0.4371457710796392	2	Q5KU26	1
+Cyclic nucleotide-binding domain [IPR000595]	0.671202445570381	1.2806828501098733	0.2003050859762252	1.0	0.4399306245692622	5	Q9Y4G8,Q8IY17	2
+ATPase family AAA domain-containing protein 3, N-terminal [IPR021911]	0.8601421188630448	1.2719941611518686	0.2033751938393333	1.0	0.444129642881269	2	Q5T9A4	1
+BTB/POZ domain [IPR000210]	0.6645366605948521	1.2521800353805967	0.21050426910362	1.0	0.4508224475652636	5	Q14145,O43791	2
+Pleckstrin homology domain [IPR001849]	0.4673928942386233	1.218861057972788	0.2228969322440641	1.0	0.4700996161867625	18	P31751,Q9BZF3,Q6WCQ1,P50570	4
+Intermediate filament head, DNA-binding domain [IPR006821]	0.7132604832907118	1.2122021214011802	0.225435019642632	1.0	0.4724536784633355	4	P08670	1
+Band 7 domain [IPR001107]	0.5779136080481719	1.1990186270273984	0.2305207027853959	1.0	0.478095721903211	8	O75955,Q9UJZ1,Q14254,Q99623,P35232,P27105	6
+Intermediate filament, rod domain [IPR039008]	0.5737403892714299	1.1787656205384622	0.2384915176071125	1.0	0.4888093798799528	8	P08670,P07196,P20700	3
+CYRIA/CYRIB, Rac1 binding domain [IPR009828]	0.8523579513866988	1.1724923305145685	0.2409994495128742	1.0	0.488924792324792	3	Q9NUQ9	1
+Tripartite DENN domain [IPR037516]	0.830426356589151	1.154677578337873	0.2482224846402783	1.0	0.4932113780795123	2	A4D1U4	1
+Tubulin/FtsZ, GTPase domain [IPR003008]	0.8436187399030685	1.1408653522521912	0.2539259597079577	1.0	0.4980701804020083	3	P07437,Q9BVA1	2
+Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]	0.8436187399030685	1.1408653522521912	0.2539259597079577	1.0	0.4980701804020083	3	P07437,Q9BVA1	2
+Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337]	0.8255813953488373	1.1356577807837756	0.2560998164765062	1.0	0.4988048728406581	2	O60506	1
+Plasma membrane calcium transporting P-type ATPase, C-terminal [IPR022141]	0.8149224806201565	1.0939485304493797	0.2739775524452521	1.0	0.5186488182576783	2	P20020	1
+HIT-like domain [IPR011146]	0.8123385012919928	1.083867506590604	0.278423548499886	1.0	0.5231789257193876	2	Q9NQE9	1
+Cold shock domain [IPR011129]	0.8210160189853875	1.0594300282460425	0.2894039801917309	1.0	0.5309286254252712	3	P16989	1
+Cold-shock protein, DNA-binding [IPR002059]	0.8210160189853875	1.0594300282460425	0.2894039801917309	1.0	0.5309286254252712	3	P16989	1
+Cold-shock (CSD) domain [IPR019844]	0.8210160189853875	1.0594300282460425	0.2894039801917309	1.0	0.5309286254252712	3	P16989	1
+Exosome complex component, N-terminal domain [IPR025721]	0.8045865633074921	1.053702498488141	0.2920191446944054	1.0	0.531811348514237	2	Q13868	1
+FAD-binding domain, PCMH-type [IPR016166]	0.800387596899208	1.0374152180986391	0.2995423890354445	1.0	0.53892393267509	2	Q15392	1
+FAD linked oxidase, N-terminal [IPR006094]	0.800387596899208	1.0374152180986391	0.2995423890354445	1.0	0.53892393267509	2	Q15392	1
+Class II aldolase/adducin N-terminal [IPR001303]	0.7990956072351465	1.0324115365961235	0.3018793697753894	1.0	0.5397792376254353	2	Q9UEY8	1
+Dynamin, N-terminal [IPR045063]	0.5658996528842722	1.02177192400549	0.3068888605480155	1.0	0.5426416587127186	7	P50570,Q8IWA4,O00429,O60313,Q9H4M9	5
+Dynamin-type guanine nucleotide-binding (G) domain [IPR030381]	0.5658996528842722	1.02177192400549	0.3068888605480155	1.0	0.5426416587127186	7	P50570,Q8IWA4,O00429,O60313,Q9H4M9	5
+Glutamine amidotransferase type 2 domain [IPR017932]	0.7884366925064641	0.9912806818130996	0.3215485432970255	1.0	0.5538462645739038	2	Q06203	1
+MHC class I alpha chain, alpha1 alpha2 domains [IPR001039]	0.7877906976744227	0.988796917952347	0.3227625125011848	1.0	0.5538462645739038	2	P10321	1
+MHC class I, alpha chain, C-terminal [IPR010579]	0.7877906976744227	0.988796917952347	0.3227625125011848	1.0	0.5538462645739038	2	P10321	1
+Fibronectin type II domain [IPR000562]	0.7993035655834033	0.9818548582890252	0.3261713575818274	1.0	0.5581344461814438	3	Q9UBV2	1
+Rpn11/EIF3F, C-terminal [IPR024969]	0.6467307046524764	0.9474854579057737	0.3433914629436239	1.0	0.5765556527889244	4	P51665	1
+Glycosyl transferase, family 1 [IPR001296]	0.7866491767224918	0.9370236941034936	0.3487463700723365	1.0	0.5824111066469074	3	Q9BT22	1
+Heavy metal-associated domain, HMA [IPR006121]	0.7729328165374701	0.931985043672298	0.3513442548847139	1.0	0.5855737581411898	2	P35670	1
+Heavy metal-associated domain, copper ion-binding [IPR006122]	0.7729328165374701	0.931985043672298	0.3513442548847139	1.0	0.5855737581411898	2	P35670	1
+LEM-like domain [IPR013146]	0.7722868217054217	0.9295294927150526	0.3526147481541459	1.0	0.5869071358536319	2	P42167	1
+FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]	0.5058693790016298	0.9076166141570242	0.3640808133481685	1.0	0.5921653385291268	9	Q9NWM8	1
+Endoplasmic reticulum vesicle transporter, C-terminal [IPR012936]	0.7754442649434763	0.8976089101081696	0.3693940871273908	1.0	0.5959320663003574	3	Q96RQ1,Q9Y282	2
+Endoplasmic reticulum vesicle transporter, N-terminal [IPR039542]	0.7754442649434763	0.8976089101081696	0.3693940871273908	1.0	0.5959320663003574	3	Q96RQ1,Q9Y282	2
+Ion transporter-like, CBS domain [IPR044751]	0.7587209302325575	0.8782733634943279	0.3797953873089978	1.0	0.6032143247746623	2	Q6P4Q7	1
+CNNM, transmembrane domain [IPR002550]	0.7587209302325575	0.8782733634943279	0.3797953873089978	1.0	0.6032143247746623	2	Q6P4Q7	1
+UBX domain [IPR001012]	0.7678619081748348	0.8711055732350578	0.3836965113449868	1.0	0.606401516781734	3	Q92575	1
+CBS domain [IPR000644]	0.5448074517157748	0.8652096786352822	0.3869237140843025	1.0	0.6098387028681836	6	Q6P4Q7,P51790,Q8NE01	3
+Peptidase M16, C-terminal [IPR007863]	0.5248213436628226	0.8331140100141847	0.4047804329240341	1.0	0.6234243557417649	7	Q10713,P22695	2
+Peptidase M16, N-terminal [IPR011765]	0.5248213436628226	0.8331140100141847	0.4047804329240341	1.0	0.6234243557417649	7	Q10713,P22695	2
+Zinc finger C2H2 AKAP95-type [IPR034736]	0.7457033052923724	0.7945547304270176	0.4268725604158545	1.0	0.6418511604538844	3	Q5BKZ1	1
+Syntaxin, N-terminal domain [IPR006011]	0.7446619813586999	0.790993935096976	0.4289475306466399	1.0	0.6418511604538844	3	Q13277	1
+Peptidase M28 [IPR007484]	0.7445738361458647	0.7906926861508039	0.4291233450762497	1.0	0.6418511604538844	3	Q7Z2K6	1
+Ricin B, lectin domain [IPR000772]	0.6041444876600569	0.7818803269034897	0.4342849077273178	1.0	0.6418511604538844	4	Q9UBG0	1
+MHC class I-like antigen recognition-like [IPR011161]	0.7418001997693924	0.7812265093277032	0.4346692848435463	1.0	0.6418511604538844	3	P10321	1
+Immunoglobulin C1-set [IPR003597]	0.7418001997693924	0.7812265093277032	0.4346692848435463	1.0	0.6418511604538844	3	P10321	1
+FAD dependent oxidoreductase [IPR006076]	0.5991195414546138	0.7626856297241378	0.4456509027479907	1.0	0.650440995431678	4	Q9H9P8,Q96CU9	2
+DALR anticodon binding [IPR008909]	0.7238372093023263	0.7496916944664244	0.4534404108937038	1.0	0.6550861755528611	2	P54136	1
+Arginyl-tRNA synthetase, catalytic core domain [IPR035684]	0.7238372093023263	0.7496916944664244	0.4534404108937038	1.0	0.6550861755528611	2	P54136	1
+RBM1CTR [IPR012604]	0.7225452196382414	0.745033380508033	0.456251540613759	1.0	0.6583849588382469	2	Q96E39	1
+Ras-associating (RA) domain [IPR000159]	0.7199612403100824	0.7357416899994529	0.4618879130745434	1.0	0.6616463637869061	2	Q9Y4G8	1
+Transcription factor CBF/NF-Y/archaeal histone domain [IPR003958]	0.724717285945077	0.7235208398033739	0.4693599554444718	1.0	0.668409297279656	3	Q9NR33,Q9NRF9	2
+Dynamin, GTPase domain [IPR001401]	0.7186814870043525	0.7033973773433715	0.4818081405066157	1.0	0.6783515726276605	3	P50570	1
+Chromo shadow domain [IPR008251]	0.701992860316123	0.6485652041112128	0.5166194524299086	1.0	0.6948601260445402	3	P83916	1
+Chromo domain subgroup [IPR017984]	0.701992860316123	0.6485652041112128	0.5166194524299086	1.0	0.6948601260445402	3	P83916	1
+NOPS [IPR012975]	0.7001615508885304	0.642625525923114	0.5204671158385099	1.0	0.697778320267105	3	Q15233,P23246	2
+Myotubularin-like phosphatase domain [IPR010569]	0.6912144702842262	0.6348307134611986	0.5255388296307872	1.0	0.7017455009570894	2	Q9C0I1	1
+KHDRBS, Qua1 domain [IPR032571]	0.6895994832041343	0.6293077334561744	0.5291476094071998	1.0	0.7019238779765953	2	O75525	1
+Sam68, tyrosine-rich domain [IPR032335]	0.6895994832041343	0.6293077334561744	0.5291476094071998	1.0	0.7019238779765953	2	O75525	1
+Chromatin target of PRMT1 protein, C-terminal [IPR025715]	0.6886304909560743	0.6260020246188512	0.5313136133574996	1.0	0.7019238779765953	2	Q86V81	1
+SLC12A transporter, C-terminal [IPR018491]	0.6873385012919848	0.6216039295189206	0.5342023365230297	1.0	0.7019238779765953	2	Q9BXP2	1
+Amino acid permease/ SLC12A domain [IPR004841]	0.6873385012919848	0.6216039295189206	0.5342023365230297	1.0	0.7019238779765953	2	Q9BXP2	1
+Zinc finger, CHHC-type [IPR012996]	0.6927302100161581	0.6186906070214698	0.5361201990412408	1.0	0.7029460991566808	3	P52597,P31943	2
+Dbl homology (DH) domain [IPR000219]	0.6821705426356465	0.6041223163974845	0.5457623235681066	1.0	0.7118018804508239	2	Q9Y4F1	1
+Serine-threonine/tyrosine-protein kinase, catalytic domain [IPR001245]	0.4643275190785022	0.5635479057403918	0.5730618486112706	1.0	0.7330280213896413	7	Q15375	1
+PABP, RNA recognition motif 2 [IPR045305]	0.6592377260981932	0.528841623215299	0.5969153208822118	1.0	0.7453972600606198	2	P11940	1
+Man1/Src1, C-terminal [IPR018996]	0.6563307493540071	0.519585830964695	0.6033522757886349	1.0	0.7489372776580319	2	Q9Y2U8	1
+SET domain [IPR001214]	0.4164890629472237	0.5163250631280207	0.6056273942022492	1.0	0.7495239824080415	10	Q15047	1
+Zinc finger, RanBP2-type [IPR001876]	0.4498115859778113	0.5016339029023796	0.6159250666607621	1.0	0.7526639630412686	7	P98175,Q92804	2
+CARG-binding factor, N-terminal [IPR012956]	0.6437338501291996	0.4802866126844529	0.6310236067885993	1.0	0.7589437769401177	2	Q99729	1
+Radical SAM [IPR007197]	0.6476296521659506	0.480058626627432	0.6311857062728434	1.0	0.7589437769401177	3	Q5VV42	1
+Elp3/MiaB/NifB [IPR006638]	0.6476296521659506	0.480058626627432	0.6311857062728434	1.0	0.7589437769401177	3	Q5VV42	1
+FAD/NAD(P)-binding domain [IPR023753]	0.4757526261561703	0.4746686544307156	0.6350231633074439	1.0	0.7606254404474664	5	O95831	1
+Proteasome activator PA28, N-terminal domain [IPR003185]	0.6445912186715317	0.4711836771875148	0.6375095740198997	1.0	0.7628711689111031	3	Q9UL46	1
+Proteasome activator PA28, C-terminal domain [IPR003186]	0.6445912186715317	0.4711836771875148	0.6375095740198997	1.0	0.7628711689111031	3	Q9UL46	1
+Staufen, C-terminal [IPR032478]	0.6310177705977369	0.4323512820127358	0.6654861206259013	1.0	0.7797415687152547	3	O75569,Q9NUL3	2
+Immunoglobulin-like domain [IPR007110]	0.3907084028551533	0.4272425447619731	0.669202676234576	1.0	0.7820424717589073	11	P35613,Q08722,P10321	3
+OCRE domain [IPR041591]	0.6211856366377034	0.4050967266458958	0.685406412499677	1.0	0.7943413033745038	3	P78332	1
+v-SNARE, coiled-coil homology domain [IPR042855]	0.6210016155088877	0.404593932804475	0.6857760190255235	1.0	0.7943413033745038	3	O75396,P51809	2
+Longin domain [IPR010908]	0.6210016155088877	0.404593932804475	0.6857760190255235	1.0	0.7943413033745038	3	O75396,P51809	2
+Rho GTPase-activating protein domain [IPR000198]	0.6166020671834663	0.4004963615861988	0.6887909627829749	1.0	0.7970934379144352	2	O00459	1
+Armadillo repeat-containing domain [IPR006911]	0.6146640826873275	0.3950702572013099	0.6927910384833655	1.0	0.8000233707084407	2	Q8N2F6	1
+Polypyrimidine tract-binding protein1/2/3, RNA recognition motif 2 [IPR034798]	0.6101421188630354	0.3825589054401538	0.7020468450813357	1.0	0.8042272169320168	2	Q9UKA9	1
+EF-hand domain [IPR002048]	0.3283510933178334	0.3816407833335247	0.7027278291197019	1.0	0.8045501456222576	44	Q02818,O95202,P80303,Q14257,Q9BRK5,P41208,O95302,O75746,Q9NWM8,Q9UJS0	10
+JAB1/MPN/MOV34 metalloenzyme domain [IPR000555]	0.415894845420131	0.3636061786497294	0.7161521122727474	1.0	0.8155037117771547	7	O00303,P51665	2
+LSM domain, eukaryotic/archaea-type [IPR001163]	0.3838847010020122	0.361651951067913	0.7176121373421038	1.0	0.815674364550791	10	P62310,Q9Y4Y9	2
+Polyadenylate-binding protein/Hyperplastic disc protein [IPR002004]	0.6012924071082432	0.3523795556538286	0.7245536321997357	1.0	0.8161450620037655	3	Q13310,P11940	2
+Immunoglobulin I-set [IPR013098]	0.5978682170542687	0.3496845287417023	0.7265754658047769	1.0	0.817684162013044	2	P13591	1
+Glycoside hydrolase family 38, N-terminal domain [IPR000602]	0.5907622739018058	0.3314009783594102	0.7403416259863029	1.0	0.8255339471696695	2	O00754	1
+Glycosyl hydrolase family 38, C-terminal [IPR011682]	0.5907622739018058	0.3314009783594102	0.7403416259863029	1.0	0.8255339471696695	2	O00754	1
+Glycoside hydrolase family 38, central domain [IPR015341]	0.5907622739018058	0.3314009783594102	0.7403416259863029	1.0	0.8255339471696695	2	O00754	1
+Protein kinase C-like, phorbol ester/diacylglycerol-binding domain [IPR002219]	0.4335596508244424	0.3270748534273021	0.7436112707888021	1.0	0.8282634467044916	5	Q92974,Q8NEN9,Q9H0H5,P05771	4
+TRASH domain [IPR011017]	0.4466709760827426	0.2546635288829356	0.7989829873798635	1.0	0.8808937487904372	4	Q9UBW7,Q5VZL5,Q9UHA3	3
+K Homology domain, type 1 [IPR004088]	0.3203409052022807	0.252589442751278	0.8005854889997792	1.0	0.8818811457194036	22	Q9NZI8,Q07666,O75525,Q96PU8,P51513,Q92667,P61978,Q92945,Q9NQT5,Q13868,Q15637,Q96I24	12
+EF-hand, Ca insensitive [IPR014837]	0.5579967689822186	0.2501896001868131	0.8024407274156238	1.0	0.8831449558456027	3	O43707,P12814	2
+Lamin tail domain [IPR001322]	0.55728799919922	0.2486715441899431	0.8036148619609251	1.0	0.8840472136651271	3	P20700	1
+ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain [IPR004100]	0.4379200563021249	0.2321943072233575	0.8163870991235236	1.0	0.8914161104215279	4	P06576	1
+ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain [IPR000194]	0.4379200563021249	0.2321943072233575	0.8163870991235236	1.0	0.8914161104215279	4	P06576	1
+Glycerophosphodiester phosphodiesterase domain [IPR030395]	0.5445736434108582	0.226946762610578	0.8204651392816438	1.0	0.8954770439666234	2	Q9NZC3	1
+Far upstream element-binding protein, C-terminal [IPR015096]	0.5436046511627934	0.2250344547445145	0.8219524705881907	1.0	0.8967080953727747	2	Q92945	1
+SPRY-associated [IPR006574]	0.545517697475481	0.2242316160729042	0.8225770836820572	1.0	0.8969973006060895	3	P14373	1
+EF hand associated, type-2 [IPR013567]	0.5326227390180944	0.2041870859042949	0.8382073027253745	1.0	0.909272704478178	2	Q8IXI2	1
+EF hand associated, type-1 [IPR013566]	0.5326227390180944	0.2041870859042949	0.8382073027253745	1.0	0.909272704478178	2	Q8IXI2	1
+MIRO domain [IPR020860]	0.5326227390180944	0.2041870859042949	0.8382073027253745	1.0	0.909272704478178	2	Q8IXI2	1
+MPN domain [IPR037518]	0.357759927246281	0.2016676335036374	0.8401765674043875	1.0	0.9106170876081436	8	O00303,P51665	2
+Rad60/SUMO-like domain [IPR022617]	0.5274547803617567	0.1949033304506786	0.8454686268721407	1.0	0.9155573889088504	2	Q8NCF5	1
+Hotdog acyl-CoA thioesterase (ACOT)-type domain [IPR033120]	0.5271317829457388	0.194334310804217	0.8459141215735626	1.0	0.915642400575288	2	Q9Y305	1
+Amine oxidase [IPR002937]	0.5276435781991259	0.189954473094315	0.849344806111689	1.0	0.918558860532581	3	P50336	1
+RING-type zinc-finger, LisH dimerisation motif [IPR027370]	0.5161498708010395	0.1757723148469936	0.8604728205240757	1.0	0.9279436896707424	2	O15344	1
+Ran binding domain [IPR000156]	0.5195476575121101	0.1755774352240458	0.8606259310212818	1.0	0.9279436896707424	3	P43487,P49792	2
+Zinc finger, MYM-type [IPR010507]	0.5151808785529701	0.1742075728310948	0.8617023342821319	1.0	0.9283019533825212	2	Q9UBW7	1
+Protein of unknown function DUF3504 [IPR021893]	0.5151808785529701	0.1742075728310948	0.8617023342821319	1.0	0.9283019533825212	2	Q9UBW7	1
+Survival motor neuron [IPR010304]	0.5122739018087926	0.1695842345707121	0.865337121940891	1.0	0.9318153298413996	2	Q16637	1
+Major sperm protein (MSP) domain [IPR000535]	0.5121163166397358	0.1630179757218372	0.8705042814144057	1.0	0.9365710142858742	3	Q8NHP6,Q9P0L0	2
+Heat shock protein Hsp90, N-terminal [IPR020575]	0.4065934065934085	0.1600420203286062	0.8728479733724555	1.0	0.9385809907119862	4	Q12931,P08238,P07900	3
+Zinc finger, UBP-type [IPR001607]	0.5054909560723618	0.1592085171252223	0.8735045937578025	1.0	0.9385848240420832	2	P45974	1
+Coatomer, gamma subunit, appendage, Ig-like subdomain [IPR013040]	0.5019379844961244	0.1540026128515243	0.8776076754066191	1.0	0.9400640795250372	2	Q9Y678	1
+Coatomer subunit gamma, C-terminal [IPR032154]	0.5019379844961244	0.1540026128515243	0.8776076754066191	1.0	0.9400640795250372	2	Q9Y678	1
+3'-5' exonuclease domain [IPR002562]	0.5006459948320506	0.1521483671702101	0.8790699167528273	1.0	0.9400640795250372	2	Q9NVH0	1
+Extended synaptotagmin, C-terminal C2 domain [IPR037752]	0.4996770025839788	0.1507712219379929	0.8801561882847644	1.0	0.9400640795250372	2	Q9BSJ8	1
+Synaptotagmin, SMP domain [IPR039010]	0.4996770025839788	0.1507712219379929	0.8801561882847644	1.0	0.9400640795250372	2	Q9BSJ8	1
+Extended synaptotagmin, C2B domain [IPR037749]	0.4996770025839788	0.1507712219379929	0.8801561882847644	1.0	0.9400640795250372	2	Q9BSJ8	1
+Extended synaptotagmin, C2A domain [IPR037733]	0.4996770025839788	0.1507712219379929	0.8801561882847644	1.0	0.9400640795250372	2	Q9BSJ8	1
+Synaptotagmin-like mitochondrial-lipid-binding domain [IPR031468]	0.4998384491114678	0.1436089502205609	0.8858092726702678	1.0	0.944888471702573	3	Q8NEN9,Q9BSJ8	2
+Oxidoreductase FAD/NAD(P)-binding [IPR001433]	0.4970310483140976	0.139405618814462	0.889129632544648	1.0	0.9472153856528168	3	P16435	1
+FAD-binding domain, ferredoxin reductase-type [IPR017927]	0.4970310483140976	0.139405618814462	0.889129632544648	1.0	0.9472153856528168	3	P16435	1
+Flavoprotein pyridine nucleotide cytochrome reductase [IPR001709]	0.4970310483140976	0.139405618814462	0.889129632544648	1.0	0.9472153856528168	3	P16435	1
+TOG domain [IPR034085]	0.3547865459249641	0.1388737914652675	0.8895498816368321	1.0	0.9472586234246247	6	O00410,Q14008,Q86Y56,Q8TEX9,Q7Z460	5
+CTP synthase, N-terminal [IPR017456]	0.4899870801033611	0.1376330486009716	0.8905304350736316	1.0	0.9474940023491304	2	P17812	1
+CTP synthase GATase domain [IPR033828]	0.4899870801033611	0.1376330486009716	0.8905304350736316	1.0	0.9474940023491304	2	P17812	1
+SMARCC, N-terminal [IPR032450]	0.4848191214470349	0.1310911947246585	0.895703166643919	1.0	0.9501613098539872	2	Q92922	1
+SMARCC, SWIRM-associated domain [IPR032448]	0.4848191214470349	0.1310911947246585	0.895703166643919	1.0	0.9501613098539872	2	Q92922	1
+SMARCC, C-terminal [IPR032451]	0.4848191214470349	0.1310911947246585	0.895703166643919	1.0	0.9501613098539872	2	Q92922	1
+ERM family, FERM domain C-lobe [IPR041789]	0.4894991922455421	0.1285585015360722	0.8977070047147289	1.0	0.951882268067679	3	P35241,P15311	2
+Pleckstrin homology domain 9 [IPR041681]	0.4783591731266261	0.1233603086082351	0.9018217860932856	1.0	0.9538132074195622	2	Q01082	1
+Pleckstrin homology domain, spectrin-type [IPR001605]	0.4783591731266261	0.1233603086082351	0.9018217860932856	1.0	0.9538132074195622	2	Q01082	1
+PSP, proline-rich [IPR006568]	0.4709302325581415	0.1150705529525597	0.9083892001699192	1.0	0.9599453851859164	2	Q6NZY4	1
+Fzo/mitofusin HR2 domain [IPR006884]	0.4693152454780356	0.1133518907971656	0.909751579387287	1.0	0.9606378536562044	2	Q8IWA4	1
+SWAP/Surp [IPR000061]	0.3450840879689454	0.1132724878739748	0.9098145283325094	1.0	0.9606378536562044	6	Q8IWZ8,Q8IWX8,Q8IX01,O15042,Q12872	5
+SWIRM domain [IPR007526]	0.3778280542986445	0.1058647947660646	0.9156896267639674	1.0	0.9643924097830724	4	Q8NB78,Q8TAQ2,Q92922	3
+Zinc finger, GATA-type [IPR000679]	0.3736263736263757	0.0989442118717331	0.9211825651138356	1.0	0.9697681434426244	4	Q8WXI9,O94776,Q13330	3
+Guanylate kinase-like domain [IPR008144]	0.3476178346162796	0.0967875913474145	0.922895078336641	1.0	0.9706776102601568	5	Q9NZW5	1
+Guanylate kinase/L-type calcium channel beta subunit [IPR008145]	0.3476178346162796	0.0967875913474145	0.922895078336641	1.0	0.9706776102601568	5	Q9NZW5	1
+Peptidase M3A/M3B catalytic domain [IPR001567]	0.463974151857831	0.0963864984280703	0.9232136148887182	1.0	0.9706776102601568	3	Q9BYT8,P52888	2
+Ancestral coatomer element 1, Sec16/Sec31 [IPR024298]	0.4447674418604621	0.0907217615326814	0.9277136787312472	1.0	0.9745876330250366	2	O94979	1
+Glutamine amidotransferase [IPR017926]	0.3603749191984507	0.0787687308119541	0.937216575941809	1.0	0.9792107860028532	4	P27708,P17812,Q9NRF8	3
+Protein of unknown function DUF3715 [IPR022188]	0.4257105943152409	0.0773166269315732	0.9383716641213408	1.0	0.980007242353598	2	Q9UK61	1
+EH domain [IPR000261]	0.3581124757595366	0.0755725957298929	0.9397591395373064	1.0	0.9805024537464876	4	Q9H223,Q96D71,Q9H4M9	3
+ATP-dependent RNA helicase eIF4A, DEAD-box helicase domain [IPR044728]	0.4215116279069777	0.0748029992115571	0.9403714554801146	1.0	0.9805024537464876	2	Q14240	1
+Exoribonuclease, phosphorolytic domain 1 [IPR001247]	0.3278791701564231	0.0720150913437164	0.942589897879356	1.0	0.9805024537464876	6	Q96B26	1
+SGS domain [IPR007699]	0.4118217054263534	0.0695581564296187	0.9445453425629916	1.0	0.9807077110672758	2	Q9HB71	1
+Nucleoporin, Nup133/Nup155-like, C-terminal [IPR007187]	0.3911498708010401	0.0607045066611451	0.951594542506068	1.0	0.985975242339136	2	Q8WUM0	1
+DNA-directed RNA polymerase, RpoA/D/Rpb3-type [IPR011263]	0.3779069767441838	0.0564707970197855	0.9549667589919276	1.0	0.9863104443427996	2	O15160	1
+DNA-directed RNA polymerase, insert domain [IPR011262]	0.3779069767441838	0.0564707970197855	0.9549667589919276	1.0	0.9863104443427996	2	O15160	1
+Methyltransferase type 11 [IPR013216]	0.4197092084006251	0.0563279233046132	0.9550805745620056	1.0	0.9863104443427996	3	Q6FI81,Q6UX53	2
+PTBP1, RNA recognition motif 2-like [IPR021790]	0.3410562735573433	0.0537576339892072	0.9571282638602808	1.0	0.9875004362388744	4	Q8WVV9	1
+Tudor domain [IPR002999]	0.3079266290074259	0.0523219174067371	0.9582721896685992	1.0	0.9879707079434524	9	Q15047	1
+ZU5 domain [IPR000906]	0.3439922480620134	0.0495121209390926	0.9605111779351356	1.0	0.9882045761265974	2	Q12955	1
+Ras GTPase-activating domain [IPR001936]	0.4090468497576759	0.0493484849855038	0.9606415811279614	1.0	0.9882045761265974	3	Q14C86,P46940	2
+Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain [IPR008333]	0.3217054263565829	0.0470978044769867	0.962435277171211	1.0	0.9885365950994788	2	Q9UHQ9	1
+MIT domain [IPR007330]	0.313630490956067	0.046509100310234	0.962904480938192	1.0	0.9885365950994788	2	Q8N0X7	1
+DNA2/NAM7 helicase-like, C-terminal [IPR041679]	0.3345184227537189	0.0464360054669443	0.96296273924096	1.0	0.9885365950994788	4	P42694,Q9HCE1,Q92900	3
+Alanyl-tRNA synthetase, class IIc, N-terminal [IPR018164]	0.2803617571059345	0.0451179817985552	0.964013268614374	1.0	0.9889856518062758	2	Q5JTZ9	1
+Thioredoxin domain [IPR013766]	0.282820542626974	0.0426794475923755	0.9659570630843096	1.0	0.989644327798179	25	O43819,Q8IXB1,Q9H1E5	3
+Death domain [IPR000488]	0.3660743134087237	0.0297150470173922	0.9762943114366474	1.0	0.997075033579384	3	Q12955,Q96FV9	2
+DNA2/NAM7 helicase, helicase domain [IPR041677]	0.3344103392568671	0.0219583874682552	0.9824811495165652	1.0	1.0	3	P42694,Q92900	2
+NIPSNAP [IPR012577]	0.3334410339256894	0.0217873933761458	0.9826175504298889	1.0	1.0	3	Q9BPW8,Q9UFN0	2
+Myosin tail [IPR002928]	0.3089202318550329	0.0184590399575817	0.9852726533719316	1.0	1.0	3	P35580	1
+Protein-tyrosine phosphatase, catalytic [IPR003595]	0.2694033333890204	0.0159299862492793	0.9872902474674234	1.0	1.0	3	P18031	1
+PDZ domain [IPR001478]	0.2758629674514232	0.0152275202640349	0.9878506662097628	1.0	1.0	18	Q9Y4G8,Q8WWI1,Q96RT1,Q9NZW5,O43464	5

interpro_family/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "Mitochondrial carrier protein [IPR002067]", "1": "Proteasome B-type subunit [IPR023333]"}