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interpro_active_site/advanced/idx2term.json

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+{}

interpro_active_site/basic/idx2term.json

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+{}

interpro_active_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:e86545cee6f840dc3838abcd0458e2df22b4181818e46340b088e839c9666750
+size 74373

interpro_active_site/df_merge.tsv

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+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_active_site/metrics.json

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+{
+    "type_of_task": "ranksum",
+    "signature_size": 2974,
+    "annotations_size": 53,
+    "title": "Average number of proteins per term",
+    "value": 2.547169811320755
+}

interpro_active_site/paths.json

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+{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C220/C220_val_log2fc"}

interpro_active_site/result.tsv

@@ -0,0 +1,2 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Serine carboxypeptidase, serine active site [IPR018202]	0.8391114102995505	1.2584681372605744	0.2082225034049662	0.9999957736332564	0.3047285400456432	3	Q9HB40,P10619	2

interpro_active_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["ATP synthase, F0 complex, subunit A, active site [IPR023011]", "ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenylosuccinate synthase,  active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Coenzyme A transferase active site [IPR004164]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]", "Uracil-DNA glycosylase, active site [IPR018085]"], "available_proteins": ["ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADSS", "AKT2", "APEH", "ARAF", "ATP5A1", "ATP5B", "ATP6", "ATP6V1A", "ATP6V1B2", "AURKA", "AURKB", "BLMH", "CAMK1", "CAMK2G", "CAPN1", "CAPN2", "CDC34", "CDC7", "CDK1", "CDK2", "CDK4", "CDK5", "CDK6", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CTSA", "CTSB", "CTSC", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "EPHA7", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLUD1", "GSR", "HADHB", "HMGCL", "HMGCS1", "LDHA", "LDHB", "LONP1", "MAP2K2", "MAPK1", "MASTL", "MDH1", "MDH2", "MTMR14", "MTMR2", "NEK9", "NME1", "OXCT1", "PAK2", "PBK", "PGAM1", "PIK3R4", "PKM", "PKMYT1", "PKN1", "PKN2", "PLK1", "PREP", "PRKAA2", "PRKACA", "PRKCB", "PRPF4B", "PTK7", "PTPMT1", "PTPN1", "PTPN11", "PTPRF", "RNASET2", "ROCK1", "RPS6KA1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SRPK2", "SUCLG1", "TALDO1", "TAOK1", "TIGAR", "TOP1", "TPI1", "TPP2", "TTK", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "ULK3", "UMPS", "UNG", "VRK1"], "leading_proteins": ["CTSA", "SCPEP1"]}

interpro_binding_site/advanced/idx2term.json

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+{"0": "EF-Hand 1, calcium-binding site [IPR018247]"}

interpro_binding_site/basic/idx2term.json

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+{"0": "EF-Hand 1, calcium-binding site [IPR018247]"}

interpro_binding_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:c58b2f293eafd34a5b3d5977b9c45f064c44aa1ba038a36a9583500f938e7906
+size 70982

interpro_binding_site/df_merge.tsv

@@ -0,0 +1,2 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+EF-Hand 1, calcium-binding site [IPR018247]	10	36	2.3175072589139045	0.0204761156912216	10.019417475728156	36.70631067961165	0.9532938980945532	0.3894555773109194	3.76037227687173	3.057484685571999	1.1082350706804749	0.3408841825650379	0.0009224643069731	0.0551599902794207	0.1731294929006003	0.0026393662320255	0.001172270128245

interpro_binding_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2974,
+    "annotations_size": 31,
+    "title": "Average number of proteins per term",
+    "value": 4.32258064516129
+}

interpro_binding_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C220/C220_val_log2fc"}

interpro_binding_site/result.tsv

@@ -0,0 +1,5 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+EF-Hand 1, calcium-binding site [IPR018247]	0.4926393451091835	2.3175072589139045	0.0204761156912216	0.473418092137227	0.0577054169479882	36	Q9Y680,Q02818,O95202,Q96AY3,Q9NWM8,O95302,Q9BRK5,Q6NUK1,Q14257,P80303	10
+Peptidase M16, zinc-binding site [IPR001431]	0.6779845601081622	1.4250643011888682	0.1541386147353241	0.9944246109547058	0.2884846628974449	5	P22695	1
+Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]	0.6554508748317676	0.5461297157331619	0.5849767747024133	0.9999999999985536	0.6253200005439591	2	P34897	1
+Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]	0.5985868102288091	0.3594622889579756	0.7192492841892115	1.0	0.7192492841892115	2	O75600	1

interpro_binding_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "APOBEC/CMP deaminase, zinc-binding [IPR016192]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Coenzyme A transferase binding site [IPR004163]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "AKT2", "APEX1", "ARAF", "AURKA", "AURKB", "BPNT1", "CALM3", "CALU", "CAMK1", "CAMK2G", "CAPN1", "CAPN2", "CDC7", "CDK1", "CDK2", "CDK4", "CDK5", "CDK6", "CETN2", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A2", "CYB5B", "DBT", "DCTD", "DLAT", "DLST", "DST", "EHD1", "EHD4", "EIF2AK2", "EPHA7", "EPS15L1", "FKBP10", "FKBP14", "FKBP7", "FKBP9", "GCAT", "GOT1", "GOT2", "GPD2", "HK1", "HK2", "HMBS", "IDE", "ILKAP", "IMPA1", "IQGAP1", "IQGAP2", "LETM1", "MACF1", "MAP2K2", "MAPK1", "MAPK14", "MCCC1", "METAP2", "MICU1", "MYH10", "MYH9", "MYO1B", "MYO1C", "MYO1D", "NRDC", "NUCB1", "NUCB2", "OXCT1", "OXSR1", "PA2G4", "PAK2", "PC", "PCCA", "PDCD6", "PEF1", "PGD", "PKMYT1", "PKN1", "PKN2", "PLCG1", "PLK1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1G", "PRKAA2", "PRKACA", "PRKCB", "PRKCSH", "PSAT1", "RAB18", "RCN1", "RCN2", "RHOT1", "RHOT2", "ROCK1", "RPS6KA1", "RPS6KA3", "S100A11", "SDF4", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "SRPK2", "STK26", "STK4", "TAOK1", "TKT", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4B", "TUBB6", "ULK3", "UQCRC2", "VRK1"], "leading_proteins": ["FKBP10", "FKBP14", "FKBP7", "FKBP9", "GCAT", "LETM1", "NUCB1", "NUCB2", "RCN2", "SDF4", "SHMT2", "SLC25A24", "UQCRC2"]}

interpro_conserved_site/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "Syntaxin/epimorphin, conserved site [IPR006012]"}

interpro_conserved_site/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Syntaxin/epimorphin, conserved site [IPR006012]", "1": "Intermediate filament protein, conserved site [IPR018039]"}

interpro_conserved_site/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:4235c696420bf09eb1ca8779d56aa3f21cf2888de21435090bca24640df97f67
+size 87135

interpro_conserved_site/df_merge.tsv

@@ -0,0 +1,2 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+Syntaxin/epimorphin, conserved site [IPR006012]	5	7	2.3053453046365	0.021147242121142	2.592233009708738	5.847087378640777	0.9961908981999794	0.2839139128702306	1.4759357288864456	1.4239341993278547	1.138258151200134	0.2914162845337057	0.0022674499040627	1.0	0.0065261066260236	0.0368360647660487	0.0025257820396667

interpro_conserved_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2974,
+    "annotations_size": 270,
+    "title": "Average number of proteins per term",
+    "value": 2.6259259259259258
+}

interpro_conserved_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C220/C220_val_log2fc"}

interpro_conserved_site/result.tsv

@@ -0,0 +1,31 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Syntaxin/epimorphin, conserved site [IPR006012]	0.805452902497199	2.3053453046364996	0.021147242121142	0.9968833389912176	0.1520674687809708	7	Q12846,Q9P2W9,Q86Y82,Q13190,O60499	5
+Haem oxygenase conserved site [IPR018207]	0.9639973082099615	1.8123112424761223	0.0699381183961331	0.9999999968508146	0.2863424780865587	2	P30519	1
+Intermediate filament protein, conserved site [IPR018039]	0.6854349291975668	1.7902216913241875	0.0734182793224751	0.9999999988555242	0.2863424780865587	8	P07197,P07196,Q03252,P20700,P02545,P08670,Q16352	7
+Tetraspanin, conserved site [IPR018503]	0.9596095590710167	1.7379756989008786	0.0822150958146266	0.9999999999128945	0.2929856859860177	3	O60637,O43657	2
+Glycoside hydrolase family 27/36, conserved site [IPR000111]	0.8691117092866761	1.409287592086054	0.1587501462533906	1.0	0.4286253948841548	2	P06280	1
+Sterol reductase, conserved site [IPR018083]	0.8522880215343263	1.337721818554238	0.1809871357890031	1.0	0.4527656861606566	2	Q14739	1
+Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]	0.8566038323580034	1.328252476403081	0.1840947137133426	1.0	0.4560144284642431	3	Q8N4Q0	1
+Lysosome-associated membrane glycoprotein, conserved site [IPR018134]	0.8209959623149434	1.2050726959340272	0.2281752392941993	1.0	0.4928585168754706	2	P11279	1
+3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]	0.8172947510094216	1.1894455800593078	0.2342643737015519	1.0	0.5019950865033256	2	P40939	1
+Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]	0.7974427994616407	1.1059530069738566	0.2687468599125022	1.0	0.5296470961779242	2	Q06481	1
+Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]	0.7974427994616407	1.1059530069738566	0.2687468599125022	1.0	0.5296470961779242	2	Q06481	1
+Amyloidogenic glycoprotein,  copper-binding domain conserved site [IPR019744]	0.7974427994616407	1.1059530069738566	0.2687468599125022	1.0	0.5296470961779242	2	Q06481	1
+Thioredoxin, conserved site [IPR017937]	0.4721723877634032	1.0834338657540803	0.2786158906599689	1.0	0.5417946803775714	12	Q96JJ7,Q9H1E5,Q9H3N1	3
+Guanylate kinase, conserved site [IPR020590]	0.653684501511699	1.0588480223723318	0.2896689991731915	1.0	0.546792277766913	4	Q9NZW5	1
+Proteasome beta-type subunit, conserved site [IPR016050]	0.5436787471126108	1.0576165664408648	0.2902302866961936	1.0	0.546792277766913	8	P49721,P28070	2
+Glycoside hydrolase, family 29, conserved site [IPR018526]	0.766487213997317	0.9772481114045464	0.3284463347099189	1.0	0.5872881481568086	2	Q9BTY2	1
+AMP-binding, conserved site [IPR020845]	0.5069046817110128	0.6274141130566464	0.5303878189903968	1.0	0.749762885483807	5	Q6P1M0,O95573,Q4G176,P33121	4
+Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]	0.6708382006983836	0.6112633000348304	0.5410252831142306	1.0	0.75297333216929	3	P04439	1
+ABC transporter-like, conserved site [IPR017871]	0.4249277868990854	0.5315284938451899	0.595052601385774	1.0	0.7875696194811714	9	P08183,O75027,Q03518,P33527	4
+Histidine triad, conserved site [IPR019808]	0.6100269179004094	0.394376920298059	0.693302780849689	1.0	0.8547568531023563	2	Q96C86	1
+Chromo domain, conserved site [IPR023779]	0.4368474233748724	0.3344256829351684	0.7380583617735774	1.0	0.8856700341282928	5	P83916,Q13185,P45973,Q9HC52	4
+Mrp, conserved site [IPR000808]	0.5360026917900466	0.1970856947486313	0.8437604778150729	1.0	0.9532102555721944	2	Q8TB37	1
+Thiosulphate sulfurtransferase, conserved site [IPR001307]	0.5302826379542508	0.1848793374447869	0.8533236779332543	1.0	0.9599891376749112	2	P25325	1
+Aldehyde dehydrogenase, cysteine active site [IPR016160]	0.3543956031186484	0.1313831921638666	0.895472184114882	1.0	0.9691553568920293	7	P51648	1
+Profilin conserved site [IPR027310]	0.4929340511440145	0.1166259405537898	0.9071564804095728	1.0	0.9712187563165244	2	P35080	1
+Polyprenyl synthetase, conserved site [IPR033749]	0.4724091520861374	0.0874641662049151	0.9303025674674876	1.0	0.9889043040008728	2	O95749	1
+Malic enzyme, conserved site [IPR015884]	0.4576043068640729	0.0699220455081227	0.9442557062934394	1.0	0.9996905191195348	2	P48163	1
+Clathrin adaptor, mu subunit, conserved site [IPR018240]	0.4564119824974646	0.0573576086406506	0.9542603307819256	1.0	0.9996905191195348	3	Q96CW1,Q9Y2T2	2
+Ribosomal S11, conserved site [IPR018102]	0.4131897711978493	0.0328770720390328	0.9737726167719912	1.0	0.9996905191195348	2	P82912	1
+Cyclic nucleotide-binding, conserved site [IPR018488]	0.3543068640645997	0.0105985171377972	0.9915437651214324	1.0	1.0	2	P10644	1

interpro_conserved_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Amyloidogenic glycoprotein,  copper-binding domain conserved site [IPR019744]", "Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Band 7/stomatin-like, conserved site [IPR018080]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "CBX family C-terminal motif [IPR033773]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Clusterin, conserved site [IPR033986]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific,  conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA mismatch repair, conserved site [IPR014762]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 14-18kDa subunit, conserved site [IPR020708]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Endonuclease III-like, conserved site-2 [IPR004036]", "Endonuclease III-like, iron-sulphur cluster loop motif [IPR003651]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Ependymin, conserved site [IPR018224]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "Ferritin, conserved site [IPR014034]", "Fibrillarin, conserved site [IPR020813]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Golgin subfamily A member 2, C-terminal binding motif [IPR043937]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Heavy-metal-associated, conserved site [IPR017969]", "Helix-hairpin-helix motif [IPR000445]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site [IPR023076]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "Molybdenum cofactor biosynthesis, conserved site [IPR008284]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NADH:ubiquinone oxidoreductase, subunit 1, conserved site [IPR018086]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M22, conserved site [IPR017860]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P,  conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S14, conserved site [IPR018271]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Transcription factor TFIIB, conserved site [IPR023486]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "Tyrosine-protein kinase, receptor class V, conserved site [IPR001426]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]"], "available_proteins": ["AAAS", "AAMP", "ABCB1", "ABCB7", "ABCC1", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ACAA2", "ACAD9", "ACADM", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR1B", "ACTR2", "ACTR3", "ADH5", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1M1", "AP1S2", "AP2M1", "AP2S1", "AP3M1", "AP3S1", "APEX1", "APLP2", "APP", "ARIH2", "ATAD1", "ATAD2", "ATP5C1", "ATP5O", "ATP7B", "BAG6", "BAK1", "BAZ1A", "BAZ1B", "BCS1L", "BOP1", "BPNT1", "BRD2", "BUD31", "CAD", "CALR", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CBR1", "CBX1", "CBX3", "CBX5", "CBX8", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD320", "CDC40", "CDH2", "CDKAL1", "CECR2", "CETN2", "CHAF1B", "CHD1", "CHD1L", "CHD4", "CLGN", "CLU", "CMPK1", "CNDP2", "COLEC12", "COPA", "COPZ1", "CORO1B", "CORO1C", "CORO7", "CPOX", "CSTB", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CWC27", "CYP51A1", "DCAF13", "DCAF7", "DCPS", "DCXR", "DDT", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX55", "DDX6", "DHCR7", "DHFR", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIMT1", "DIS3", "DLG3", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC2", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DRG1", "DRG2", "DSC3", "DSG2", "DST", "DTYMK", "DYNLL2", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4E", "ENO1", "ENO2", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPRS", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FARP1", "FBL", "FCGRT", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FTL", "FUCA1", "FUCA2", "GAA", "GALK1", "GANAB", "GART", "GCDH", "GEMIN5", "GFM1", "GGPS1", "GLA", "GLB1", "GLO1", "GMPPB", "GNPDA1", "GNS", "GOLGA2", "GPHN", "GPI", "GRHPR", "GRWD1", "GSPT1", "GTF2B", "GTF3C2", "GUF1", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HGS", "HIBADH", "HINT2", "HLA-A", "HLA-B", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCR", "HMOX1", "HMOX2", "HSD17B10", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IDH1", "IDH2", "IDH3A", "IDH3B", "ILVBL", "IMPA1", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "IQGAP1", "IQGAP2", "IVD", "KDM2A", "KDSR", "KIF11", "KIF14", "KIF18B", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFC1", "LAMP1", "LAMP2", "LARS", "LARS2", "LBR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRP1", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK14", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME1", "ME2", "MGST2", "MIF", "MKRN2", "MPI", "MPP1", "MPP6", "MPST", "MRC2", "MRPL24", "MRPL3", "MRPS11", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "MVK", "NAGA", "ND1", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS8", "NDUFV1", "NEFL", "NEFM", "NES", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NSD2", "NSF", "NTHL1", "NUBP2", "NUBPL", "NUDT1", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL3", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PBRM1", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PEBP1", "PEPD", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHGDH", "PHIP", "PI4KB", "PLEC", "PLOD1", "PLOD2", "PLRG1", "PLS3", "PNP", "PNPLA6", "POLA1", "POLD1", "POLR1B", "POLR1C", "POLR2B", "POLR2C", "POLR2E", "POLR2F", "PPIB", "PPIC", "PPID", "PPIF", "PPIH", "PPIL1", "PPIL3", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PUS7", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "RACK1", "RAE1", "RANBP2", "RARS", "RARS2", "RBBP7", "RCL1", "RDH13", "RDX", "RIDA", "RNF14", "RNF20", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS24", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "RSL24D1", "RTN4IP1", "S100A11", "SART1", "SBDS", "SCD", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB6", "SERPINH1", "SLC1A5", "SLC25A42", "SLC27A4", "SLIT2", "SMARCA4", "SMS", "SMU1", "SNRNP40", "SORD", "SPATA5", "SPATA5L1", "SPTBN1", "SPTBN2", "SRCAP", "SRM", "STAM", "STMN1", "STOM", "STRN", "STX10", "STX12", "STX18", "STX3", "STX4", "STX5", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SV2A", "SYNE2", "TAP1", "TBL3", "TCP1", "TFB1M", "THOC6", "TK1", "TLN1", "TMX1", "TMX3", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRAF2", "TRIM21", "TRIM25", "TRIM28", "TRIM33", "TRIP13", "TRMT11", "TSFM", "TSPAN10", "TSPAN3", "TSPAN6", "TST", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4B", "TUBB6", "TUFM", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UHRF1", "USP10", "USP11", "USP14", "USP28", "USP36", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VAT1", "VCL", "VCP", "VIM", "VPS4A", "VPS4B", "WARS", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR3", "WDR36", "WDR41", "WDR48", "WDR5", "WDR61", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2"], "leading_proteins": ["ABCB1", "ABCB7", "ABCC1", "ACSF3", "ACSL1", "ACSL3", "ALDH3A2", "AP2M1", "AP3M1", "APLP2", "CBX1", "CBX3", "CBX5", "CBX8", "DCPS", "FUCA2", "GGPS1", "GLA", "HADHA", "HLA-A", "HMOX2", "INA", "LAMP1", "LBR", "LMNA", "LMNB1", "LMNB2", "ME1", "MPP6", "MPST", "MRPS11", "NEFL", "NEFM", "NUBPL", "PFN2", "PRKAR1A", "PSMB2", "PSMB4", "SLC27A4", "STX10", "STX12", "STX18", "STX4", "STX5", "TAP1", "TMX1", "TMX3", "TMX4", "TSPAN3", "TSPAN6", "VIM", "ZADH2"]}

interpro_domain/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "EF-hand domain [IPR002048]", "1": "Band 7 domain [IPR001107]"}

interpro_domain/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "EF-hand domain [IPR002048]", "1": "Band 7 domain [IPR001107]", "2": "Target SNARE coiled-coil homology domain [IPR000727]", "3": "Intermediate filament, rod domain [IPR039008]", "4": "Immunoglobulin-like domain [IPR007110]", "5": "Phospholipid/glycerol acyltransferase [IPR002123]", "6": "Thioredoxin domain [IPR013766]", "7": "Sterile alpha motif domain [IPR001660]", "8": "RNA recognition motif domain, eukaryote [IPR003954]", "9": "JAB1/MPN/MOV34 metalloenzyme domain [IPR000555]"}

interpro_domain/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:c621c03b8a5fa44051e916b37bf5e1e27542197a8334821368e4931c644010b3
+size 298497

interpro_domain/df_merge.tsv

@@ -0,0 +1,7 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+EF-hand domain [IPR002048]	14	42	2.903306032804643	0.0036924562104008	12.385922330097088	43.512135922330096	1.0171858714399242	0.3947118087831401	4.608360476919044	4.087317384177653	1.201458704248258	0.3652478399429377	4.805909081633214e-05	0.0832266786690803	0.2461545823107532	0.0005989342875991	6.71908161905798e-05
+FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]	4	11	2.4880667042620086	0.0128439640366668	3.1262135922330097	10.111650485436892	0.9686720267359892	0.3700536707457866	1.7316562118191232	1.203619216216406	0.9607394322697528	0.3108814801432357	0.0001907872283095	0.0607401038440192	0.1169218221283287	0.0031665778749487	0.0002190726437552
+Cytochrome b5-like heme/steroid binding domain [IPR001199]	4	6	2.1687478005237395	0.0301018361917864	2.813106796116505	6.104368932038835	1.6405397264547834	0.1100883340733615	1.2852875686886795	0.8042848477475721	1.100790504333474	0.1612592696854457	0.000122001793767	0.0561990347849709	0.0055563644779973	0.0024789777341693	0.0001402534450405
+P-type ATPase, haloacid dehalogenase domain [IPR044492]	4	5	2.063733772997012	0.039042965342845	2.941747572815534	6.145631067961165	0.9567723497044874	0.2732808833570771	1.8358630293390923	1.459204245106796	1.2102525517005158	0.2943240638910574	0.0167170186699105	1.0	1.0	0.4108142183097444	0.0184399659986801
+Band 7 domain [IPR001107]	7	8	2.034318154650474	0.0419195279005741	3.825242718446602	7.354368932038835	0.2848798017769268	0.3662852929750465	1.8717479731706237	0.7075565364256523	1.25010454777189	0.3076860385713043	0.0065989327860597	1.0	1.0	1.0	0.0071635939680117
+Tim10-like [IPR004217]	3	5	1.9892556971379796	0.0466729870130147	1.2005141388174807	2.5167095115681235	0.6297728943083764	0.3036466482483842	1.011959204869136	1.1903007636326162	1.51035532787006	0.2968335314780513	0.0017428204603846	1.0	0.0557540441617295	0.1342523552784823	0.001897897013483

interpro_domain/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2974,
+    "annotations_size": 2448,
+    "title": "Average number of proteins per term",
+    "value": 2.110294117647059
+}

interpro_domain/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C220/C220_val_log2fc"}

interpro_domain/result.tsv

@@ -0,0 +1,169 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+EF-hand domain [IPR002048]	0.5433391212156761	2.903306032804643	0.0036924562104008	0.9998832951311823	0.141331215100908	42	Q9Y680,Q02818,Q9UJS0,O75071,Q8IYU8,O95202,Q96AY3,Q8NF37,Q9NWM8,O95302,Q9BRK5,Q6NUK1,Q14257,P80303	14
+FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]	0.7208920730359976	2.4880667042620086	0.0128439640366668	0.999999999999982	0.141331215100908	11	Q96AY3,Q9Y680,Q9NWM8,O95302	4
+TRAM/LAG1/CLN8 homology domain [IPR006634]	0.9242424242424294	2.224973128168226	0.0260830421438549	1.0	0.1522952529404522	4	Q96CP7,Q15629,Q96G23	3
+Cytochrome b5-like heme/steroid binding domain [IPR001199]	0.7900241226067679	2.1687478005237395	0.0301018361917864	1.0	0.1583709173144682	6	O43169,O15173,O00264,O95864	4
+P-type ATPase, haloacid dehalogenase domain [IPR044492]	0.8174469518356344	2.063733772997012	0.039042965342845	1.0	0.1793192854770817	5	P35670,P05023,Q9HD20,P16615	4
+Band 7 domain [IPR001107]	0.7346594740391011	2.034318154650474	0.0419195279005741	1.0	0.1848647838592249	8	Q14254,Q9UJZ1,P27105,P35232,Q99623,O75477,O75955	7
+Tim10-like [IPR004217]	0.8007719439061067	1.9892556971379791	0.0466729870130147	1.0	0.1982393197971919	5	Q9Y5J9,Q9Y5J6,Q9Y5J7	3
+LEM domain [IPR003887]	0.7426594526830846	1.9475700479836804	0.0514664305740926	1.0	0.2089383450172117	6	P42167,Q86XL3	2
+ABC transporter type 1, transmembrane domain [IPR011527]	0.7878073425395749	1.9309641692697916	0.053487483608904	1.0	0.2150377541826532	5	P08183,O75027,Q03518,P33527	4
+Target SNARE coiled-coil homology domain [IPR000727]	0.6634737811861067	1.8266783862988416	0.0677481398442967	1.0	0.2516653206962646	9	Q12846,Q86Y82,Q13190,O60499,Q9UNK0	5
+Intermediate filament, rod domain [IPR039008]	0.6854349291975668	1.7902216913241875	0.0734182793224751	1.0	0.2635307152220221	8	P07197,P07196,Q03252,P20700,P02545,P08670,Q16352	7
+MENTAL domain [IPR019498]	0.9512113055181723	1.7582645317640118	0.0787025096365168	1.0	0.2750845121966474	2	O95772	1
+Syntaxin, N-terminal domain [IPR006011]	0.8028800104594825	1.7122984557013017	0.0868416811367065	1.0	0.2880602105998071	4	Q86Y82,Q12846	2
+Immunoglobulin-like domain [IPR007110]	0.6084428732481896	1.6859094745423766	0.0918132367723809	1.0	0.2973400216428712	10	P01889,P35613,P10321,P04439,Q08722	5
+GMP phosphodiesterase, delta subunit [IPR008015]	0.9414338606529752	1.666093155292813	0.0956948616304087	1.0	0.3003127665377353	3	Q13432,A6NIH7	2
+Reticulon [IPR003388]	0.9269606193200888	1.6086804985543997	0.1076862221487673	1.0	0.3172532421682301	3	O95197,Q9NQC3	2
+Ricin B, lectin domain [IPR000772]	0.7090108402664044	1.5699351537604165	0.1164301982020972	1.0	0.3267223427158505	5	Q8N4A0	1
+START domain [IPR002913]	0.904104979811578	1.5582722916756089	0.1191687143720701	1.0	0.327331803778814	2	Q14849	1
+Complex 1 LYR protein domain [IPR008011]	0.9007402422611084	1.543951796388621	0.1226000106803886	1.0	0.3323431581644318	2	Q9NU23	1
+GOLD domain [IPR009038]	0.6463293374944397	1.5355341936062463	0.1246526645606216	1.0	0.3349612764483005	7	Q15363,P49755,Q9Y3B3	3
+Intermediate filament head, DNA-binding domain [IPR006821]	0.7616161616161614	1.5330785372969338	0.1252565051971554	1.0	0.3356006832784844	4	P08670,P07197,Q16352	3
+Phospholipase D/Transphosphatidylase [IPR001736]	0.8977119784656848	1.5310612339595906	0.125754259568728	1.0	0.3357179335350301	2	Q8N2A8	1
+Importin-alpha, importin-beta-binding domain [IPR002652]	0.745869765291504	1.4642024687297417	0.1431386359039252	1.0	0.3586523855607053	4	O00505	1
+Phospholipid/glycerol acyltransferase [IPR002123]	0.6236140108223177	1.420988604055591	0.1553200724436201	1.0	0.374235765100376	7	Q9NUQ2,Q8NF37,Q92604,Q99943,O15228	5
+Alpha galactosidase A, C-terminal beta-sandwich domain [IPR035373]	0.8691117092866761	1.409287592086054	0.1587501462533906	1.0	0.3790986835087275	2	P06280	1
+MHC class I-like antigen recognition-like [IPR011161]	0.7321323440019449	1.4039450062793386	0.1603352262448272	1.0	0.3805416025538845	4	P10321,P04439	2
+Immunoglobulin C1-set [IPR003597]	0.7321323440019449	1.4039450062793386	0.1603352262448272	1.0	0.3805416025538845	4	P10321,P04439	2
+Fatty acid desaturase domain [IPR005804]	0.8660834454912552	1.3963986850447416	0.1625944708648612	1.0	0.3834597925599039	2	O15121	1
+Tim44-like domain [IPR007379]	0.8596904441453572	1.3691976957501717	0.1709374861137644	1.0	0.3989084518651052	2	Q9BRJ2	1
+FAD-binding domain, PCMH-type [IPR016166]	0.8519515477792816	1.3362917150068694	0.1814539434437594	1.0	0.4120586767628229	2	Q15392	1
+FAD linked oxidase, N-terminal [IPR006094]	0.8519515477792816	1.3362917150068694	0.1814539434437594	1.0	0.4120586767628229	2	Q15392	1
+CNNM, transmembrane domain [IPR002550]	0.8512786002691802	1.3334316864477052	0.1823901797637956	1.0	0.4130353007046918	2	Q8NE01	1
+Ion transporter-like, CBS domain [IPR044751]	0.8512786002691802	1.3334316864477052	0.1823901797637956	1.0	0.4130353007046918	2	Q8NE01	1
+Glycosyl transferase, family 1 [IPR001296]	0.8502691790040435	1.3291421005136623	0.1838010928201616	1.0	0.4150784826787415	2	Q9BT22	1
+Peptidase M16, N-terminal [IPR011765]	0.6048187738468211	1.325560743805443	0.1849852364676016	1.0	0.4162167820521038	7	P22695,Q5JRX3,Q10713	3
+Peptidase M16, C-terminal [IPR007863]	0.6048187738468211	1.325560743805443	0.1849852364676016	1.0	0.4162167820521038	7	P22695,Q5JRX3,Q10713	3
+Acyl-CoA oxidase, C-terminal [IPR002655]	0.8452220726783359	1.3077030381033248	0.1909740524841048	1.0	0.4235751836831872	2	Q15067	1
+Endoplasmic reticulum vesicle transporter, N-terminal [IPR039542]	0.8371467025572106	1.2734360996603584	0.2028633341858396	1.0	0.4329637681664651	2	Q9Y282	1
+Endoplasmic reticulum vesicle transporter, C-terminal [IPR012936]	0.8371467025572106	1.2734360996603584	0.2028633341858396	1.0	0.4329637681664651	2	Q9Y282	1
+Zinc finger, CHHC-type [IPR012996]	0.8381016492763373	1.2544426813384102	0.2096811472303752	1.0	0.4388781680728934	3	P52597,P55795	2
+FAD dependent oxidoreductase [IPR006076]	0.6927247021640028	1.230550694503809	0.2184909556562928	1.0	0.4484197777864751	4	Q96CU9	1
+Major facilitator superfamily domain [IPR020846]	0.8308260417565543	1.2254515992645607	0.2204051157044049	1.0	0.4507533193353243	3	P53985	1
+Acyltransferase, C-terminal domain [IPR032098]	0.8246971736204664	1.2207158336573636	0.2221936306330301	1.0	0.4532750064913814	2	Q9NUQ2	1
+3-hydroxyacyl-CoA dehydrogenase, C-terminal [IPR006108]	0.8172947510094216	1.1894455800593078	0.2342643737015519	1.0	0.4666226092932459	2	P40939	1
+3-hydroxyacyl-CoA dehydrogenase, NAD binding [IPR006176]	0.8172947510094216	1.1894455800593078	0.2342643737015519	1.0	0.4666226092932459	2	P40939	1
+CBS domain [IPR000644]	0.577755758011253	1.1873758445425355	0.2350794036171448	1.0	0.4674029012499852	7	Q8NE01,P51798,Q6P4Q7	3
+Sec23, C-terminal [IPR037550]	0.8129205921938178	1.1709994794216054	0.241598986401476	1.0	0.4741812670619961	2	Q15437	1
+Cation-transporting P-type ATPase, C-terminal [IPR006068]	0.816896667788616	1.1700319526867626	0.2419881104557864	1.0	0.4741812670619961	3	P05023,P16615	2
+Cation-transporting P-type ATPase, N-terminal [IPR004014]	0.816896667788616	1.1700319526867626	0.2419881104557864	1.0	0.4741812670619961	3	P05023,P16615	2
+MHC class I, alpha chain, C-terminal [IPR010579]	0.8165600807808747	1.168694488037818	0.242526743511501	1.0	0.4741812670619961	3	P10321,P04439	2
+MHC class I alpha chain, alpha1 alpha2 domains [IPR001039]	0.8165600807808747	1.168694488037818	0.242526743511501	1.0	0.4741812670619961	3	P10321,P04439	2
+Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862]	0.8075370121130623	1.1483326660600215	0.2508312588161132	1.0	0.4794981825334084	2	P13674	1
+Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337]	0.8058546433378206	1.141258025861391	0.2537625637383953	1.0	0.4826812401177869	2	O60506	1
+N-acetylgalactosaminyltransferase [IPR045885]	0.8088224793503009	1.1379745906204537	0.2551310925742593	1.0	0.4835050611297012	3	Q8N4A0	1
+ATPase family AAA domain-containing protein 3, N-terminal [IPR021911]	0.8041722745625886	1.134187761433091	0.2567157965830979	1.0	0.4835050611297012	2	Q9NVI7	1
+Pancreatic trypsin inhibitor Kunitz domain [IPR002223]	0.7974427994616407	1.1059530069738566	0.2687468599125022	1.0	0.4950280760465053	2	Q06481	1
+Amyloidogenic glycoprotein, heparin-binding [IPR015849]	0.7974427994616407	1.1059530069738566	0.2687468599125022	1.0	0.4950280760465053	2	Q06481	1
+Beta-amyloid precursor protein C-terminal [IPR019543]	0.7974427994616407	1.1059530069738566	0.2687468599125022	1.0	0.4950280760465053	2	Q06481	1
+Amyloidogenic glycoprotein, extracellular [IPR008154]	0.7974427994616407	1.1059530069738566	0.2687468599125022	1.0	0.4950280760465053	2	Q06481	1
+Amyloidogenic glycoprotein, copper-binding [IPR011178]	0.7974427994616407	1.1059530069738566	0.2687468599125022	1.0	0.4950280760465053	2	Q06481	1
+Amyloidogenic glycoprotein, E2 domain [IPR024329]	0.7974427994616407	1.1059530069738566	0.2687468599125022	1.0	0.4950280760465053	2	Q06481	1
+Marvel domain [IPR008253]	0.7923956931359464	1.0848292244749849	0.277997299316242	1.0	0.5041017694267855	2	O43760	1
+Aminopeptidase N-like , N-terminal domain [IPR045357]	0.6048575482337888	1.0804491708006578	0.279942209790841	1.0	0.5050099702048481	5	Q9NZ08,Q9UIQ6	2
+Peptidase M1, membrane alanine aminopeptidase [IPR014782]	0.6048575482337888	1.0804491708006578	0.279942209790841	1.0	0.5050099702048481	5	Q9NZ08,Q9UIQ6	2
+CARG-binding factor, N-terminal [IPR012956]	0.7833109017496633	1.046932135272905	0.2951308793802991	1.0	0.5179723731641585	2	Q99729	1
+VPS13, repeated coiled region [IPR031642]	0.7823014804845208	1.0427320914852862	0.2970723904912085	1.0	0.5179723731641585	2	Q5THJ4	1
+Vacuolar protein sorting-associated protein 13, SHR-binding domain [IPR009543]	0.7823014804845208	1.0427320914852862	0.2970723904912085	1.0	0.5179723731641585	2	Q5THJ4	1
+Vacuolar protein sorting-associated protein 13-like, N-terminal domain [IPR026854]	0.7823014804845208	1.0427320914852862	0.2970723904912085	1.0	0.5179723731641585	2	Q5THJ4	1
+Vacuolar protein sorting-associated protein 13, C-terminal [IPR031645]	0.7823014804845208	1.0427320914852862	0.2970723904912085	1.0	0.5179723731641585	2	Q5THJ4	1
+Vacuolar protein sorting-associated protein 13, second N-terminal domain [IPR031646]	0.7823014804845208	1.0427320914852862	0.2970723904912085	1.0	0.5179723731641585	2	Q5THJ4	1
+Ribosomal S6 kinase, N-terminal catalytic domain [IPR041906]	0.7678331090174999	0.982796385323028	0.3257076612438938	1.0	0.5490646323135043	2	P51812	1
+Alpha-L-fucosidase, C-terminal [IPR031919]	0.766487213997317	0.9772481114045464	0.3284463347099189	1.0	0.5514863958045355	2	Q9BTY2	1
+Tudor domain [IPR002999]	0.5804568724451862	0.9655927137075002	0.3342480227337581	1.0	0.5557351723580046	5	Q14739,Q16637	2
+Arginyl-tRNA synthetase, catalytic core domain [IPR035684]	0.7627860026918003	0.9620162463087508	0.3360414431162457	1.0	0.557337027607432	2	P54136	1
+DALR anticodon binding [IPR008909]	0.7627860026918003	0.9620162463087508	0.3360414431162457	1.0	0.557337027607432	2	P54136	1
+ERAP1-like C-terminal domain [IPR024571]	0.7616963985190037	0.952478344603334	0.3408544434135288	1.0	0.5622720198627483	3	Q9NZ08,Q9UIQ6	2
+Far upstream element-binding protein, C-terminal [IPR015096]	0.7594212651413197	0.948203223789606	0.3430260063012171	1.0	0.5650926402593403	2	Q92945	1
+Dynamin, N-terminal [IPR045063]	0.5308046959466577	0.9468553410485296	0.3437124972698524	1.0	0.565462495508467	7	O95140,O60313,Q8IWA4,Q9H223	4
+Dynamin-type guanine nucleotide-binding (G) domain [IPR030381]	0.5308046959466577	0.9468553410485296	0.3437124972698524	1.0	0.565462495508467	7	O95140,O60313,Q8IWA4,Q9H223	4
+NIPSNAP [IPR012577]	0.7520188425302867	0.9179359620688776	0.3586523928776359	1.0	0.57421913522855	2	Q9BPW8	1
+v-SNARE, coiled-coil homology domain [IPR042855]	0.7492426792325779	0.9041233175177557	0.3659300154408085	1.0	0.5809316976647855	3	O15498,O75396	2
+Longin domain [IPR010908]	0.7492426792325779	0.9041233175177557	0.3659300154408085	1.0	0.5809316976647855	3	O15498,O75396	2
+SUN coiled coil domain 2 [IPR040994]	0.7328398384925991	0.8403902743940481	0.4006896003689979	1.0	0.6119077615117323	2	Q9UH99	1
+Pumilio homology domain [IPR033133]	0.7325033647375563	0.8390422667190572	0.4014455916950064	1.0	0.612623184446764	2	Q15397	1
+Fzo/mitofusin HR2 domain [IPR006884]	0.7257738896366117	0.8121810232061119	0.4166877668669684	1.0	0.6238848032356812	2	Q8IWA4	1
+Armadillo repeat-containing domain [IPR006911]	0.7247644683714651	0.8081685493751875	0.4189935601880115	1.0	0.6244631765565615	2	Q8N2F6	1
+Acyl transferase [IPR014043]	0.7217362045760531	0.7961582689716801	0.4259400496618835	1.0	0.6314964141299793	2	P49327	1
+ELMO domain [IPR006816]	0.7176985195154792	0.7802096455576378	0.4352674857770089	1.0	0.6345624818870923	2	Q8IZ81	1
+NOPS [IPR012975]	0.6984180410636138	0.7114514744048855	0.4768045109936851	1.0	0.6702388449903034	3	P23246,Q8WXF1	2
+Diacylglycerol kinase, catalytic domain [IPR001206]	0.6982245886620673	0.7107361920720677	0.4772477276660196	1.0	0.6702388449903034	3	Q53H12	1
+Peptidase M3A/M3B catalytic domain [IPR001567]	0.6980814540558554	0.7102070621628236	0.477575742112627	1.0	0.6702388449903034	3	Q9BYT8,Q99797	2
+Prolyl 4-hydroxylase, alpha subunit [IPR006620]	0.5718657315155099	0.7066075829040979	0.4798103753070337	1.0	0.6708028547981831	4	P13674	1
+Oxoglutarate/iron-dependent dioxygenase [IPR005123]	0.5718657315155099	0.7066075829040979	0.4798103753070337	1.0	0.6708028547981831	4	P13674	1
+Lamin tail domain [IPR001322]	0.6960619320094211	0.7027509758824798	0.4822109536365162	1.0	0.6733898542511076	3	P02545,P20700	2
+Thioredoxin domain [IPR013766]	0.343150419698946	0.6939051392372991	0.4877417004370152	1.0	0.6745363340070787	24	Q9Y320,Q96JJ7,Q9H3N1,Q9H1E5,O43819	5
+TGS [IPR004095]	0.4860293154209202	0.6867909716079672	0.4922144599609155	1.0	0.6769331449350119	6	Q9NTK5	1
+AMP-dependent synthetase/ligase [IPR000873]	0.5069046817110128	0.6274141130566464	0.5303878189903968	1.0	0.7047590250752009	5	Q6P1M0,O95573,Q4G176,P33121	4
+Sterile alpha motif domain [IPR001660]	0.460215778826692	0.6233969590008881	0.5330236958516268	1.0	0.7060833373618952	8	Q13586,Q9Y3Z3,Q15375,Q6SZW1,Q9Y6Y8,Q8IXK0,Q5PRF9	7
+SCP2 sterol-binding domain [IPR003033]	0.6699448818296404	0.6080837771859164	0.5431319112069035	1.0	0.7091130232717332	3	Q6YN16	1
+RNA recognition motif domain, eukaryote [IPR003954]	0.3843921853009149	0.5698201614650558	0.5687996795832224	1.0	0.7302811130190298	13	Q14498,P38159,Q14011,Q9UHX1,Q96I25	5
+SET domain [IPR001214]	0.6587007741501005	0.5684580972672573	0.5697239507890282	1.0	0.7309665783708286	3	Q03164,Q9H7B4	2
+Serine hydroxymethyltransferase-like domain [IPR039429]	0.6554508748317676	0.5461297157331619	0.5849767747024133	1.0	0.7392259315167654	2	P34897	1
+Rhodanese-like domain [IPR001763]	0.5306397306397213	0.538879705295435	0.589969861573322	1.0	0.7426434099061657	4	Q99956,P25325,Q8NCN5	3
+ABC transporter-like, ATP-binding domain [IPR003439]	0.4249277868990854	0.5315284938451899	0.595052601385774	1.0	0.7466369903600075	9	P08183,O75027,Q03518,P33527	4
+Oxidoreductase FAD/NAD(P)-binding [IPR001433]	0.6455738808481818	0.5231892913676068	0.6008425327678621	1.0	0.7485528525803051	3	Q9UHQ9,P16435	2
+Flavoprotein pyridine nucleotide cytochrome reductase [IPR001709]	0.6455738808481818	0.5231892913676068	0.6008425327678621	1.0	0.7485528525803051	3	Q9UHQ9,P16435	2
+FAD-binding domain, ferredoxin reductase-type [IPR017927]	0.6455738808481818	0.5231892913676068	0.6008425327678621	1.0	0.7485528525803051	3	Q9UHQ9,P16435	2
+Histone-binding protein RBBP4, N-terminal [IPR022052]	0.6477119784656826	0.5189387341725535	0.6038034654834106	1.0	0.7495284539745746	2	Q16576	1
+Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain [IPR008333]	0.6453566621803539	0.5107636847925139	0.6095165408628616	1.0	0.7522249047779115	2	Q9UHQ9	1
+EH domain-containing protein, N-terminal [IPR031692]	0.6436742934051185	0.5049538746941012	0.6135912330976503	1.0	0.7530793217588518	2	Q9H223	1
+Domain of unknown function DUF5600 [IPR040990]	0.6436742934051185	0.5049538746941012	0.6135912330976503	1.0	0.7530793217588518	2	Q9H223	1
+FCP1 homology domain [IPR004274]	0.6329087782423239	0.4806293772764776	0.6307799324655741	1.0	0.7639402960475203	3	Q05D32	1
+Methyltransferase type 11 [IPR013216]	0.4691781669532393	0.4642732919043372	0.6424519566012892	1.0	0.773204439435282	5	Q9H8H3	1
+AMP-binding enzyme, C-terminal domain [IPR025110]	0.6228220673902762	0.4475908469815222	0.6544485101014554	1.0	0.7788478136744593	3	Q4G176	1
+Synaptotagmin-like mitochondrial-lipid-binding domain [IPR031468]	0.6248317631224818	0.4416539779446988	0.658739617439895	1.0	0.7795055674136925	2	Q9BSJ8	1
+Extended synaptotagmin, C-terminal C2 domain [IPR037752]	0.6248317631224818	0.4416539779446988	0.658739617439895	1.0	0.7795055674136925	2	Q9BSJ8	1
+Extended synaptotagmin, C2A domain [IPR037733]	0.6248317631224818	0.4416539779446988	0.658739617439895	1.0	0.7795055674136925	2	Q9BSJ8	1
+Synaptotagmin, SMP domain [IPR039010]	0.6248317631224818	0.4416539779446988	0.658739617439895	1.0	0.7795055674136925	2	Q9BSJ8	1
+Extended synaptotagmin, C2B domain [IPR037749]	0.6248317631224818	0.4416539779446988	0.658739617439895	1.0	0.7795055674136925	2	Q9BSJ8	1
+Zinc finger C2H2 AKAP95-type [IPR034736]	0.6183103332211268	0.4330749798011465	0.6649602989223153	1.0	0.7803560938455552	3	Q5BKZ1,O43823	2
+Glycosyltransferase 2-like [IPR001173]	0.4871682834485495	0.3753470298794235	0.7074023937956306	1.0	0.7961057930414717	4	Q8N4A0	1
+Guanylate kinase/L-type calcium channel beta subunit [IPR008145]	0.435490044909119	0.3292289997219874	0.7419826050320513	1.0	0.8170820589826637	5	Q9NZW5	1
+Guanylate kinase-like domain [IPR008144]	0.435490044909119	0.3292289997219874	0.7419826050320513	1.0	0.8170820589826637	5	Q9NZW5	1
+Chromo domain subgroup [IPR017984]	0.5693966675804736	0.2876071315805838	0.7736474852342303	1.0	0.8415293822522659	3	P83916	1
+Chromo shadow domain [IPR008251]	0.5693966675804736	0.2876071315805838	0.7736474852342303	1.0	0.8415293822522659	3	P83916	1
+Heterogeneous nuclear ribonucleoprotein U, SPRY domain [IPR035778]	0.5673283765571027	0.281988520198852	0.7779523128149297	1.0	0.8437870012277128	3	Q1KMD3	1
+Dehydrogenase, E1 component [IPR001017]	0.566285329744289	0.2692705574161455	0.7877214874708427	1.0	0.8492503628959072	2	Q02218	1
+FAD/NAD(P)-binding domain [IPR023753]	0.417732390589455	0.2634438816706322	0.7922084720429627	1.0	0.8511202735486042	5	O95831	1
+Sorting nexin Vps5-like, C-terminal [IPR015404]	0.4525252525252374	0.2590014778197521	0.7956341002560068	1.0	0.8531372218251005	4	O60749,Q9UNH7,Q9Y5X3	3
+CTP synthase, N-terminal [IPR017456]	0.5605652759084883	0.2546819258224595	0.7989687771251219	1.0	0.8548407195814242	2	Q9NRF8	1
+CTP synthase GATase domain [IPR033828]	0.5605652759084883	0.2546819258224595	0.7989687771251219	1.0	0.8548407195814242	2	Q9NRF8	1
+Cyclic nucleotide-binding domain [IPR000595]	0.4080184270577206	0.229323615027008	0.8186174003540181	1.0	0.8720519565128966	5	Q8IY17	1
+MoaB/Mog domain [IPR001453]	0.5464333781965091	0.220527840106663	0.8254600927471742	1.0	0.8766501128592725	2	Q9NQX3	1
+Threonyl/alanyl tRNA synthetase, SAD [IPR012947]	0.4353427075623025	0.2070490925378464	0.8359715187911885	1.0	0.8859126744592335	4	Q9BW92	1
+Nucleoporin, Nup133/Nup155-like, C-terminal [IPR007187]	0.5336473755047194	0.1920035369099728	0.8477394349196046	1.0	0.8972183902651069	2	O75694	1
+PABP, RNA recognition motif 2 [IPR045305]	0.5312920592193924	0.1869997633174304	0.8516608185174752	1.0	0.9005899281774425	2	Q13310	1
+Heat shock protein DnaJ, cysteine-rich domain [IPR001305]	0.5260854930999512	0.1802914832522764	0.8569237414977733	1.0	0.9049824500373378	3	O60884,Q96EY1	2
+CS domain [IPR007052]	0.3646801221729071	0.1793236511849759	0.8576835768872342	1.0	0.9053943062612976	8	Q9P035	1
+EF-hand, Ca insensitive [IPR014837]	0.5213732749915748	0.1699931673315601	0.8650155101233463	1.0	0.910386057085964	3	O43707,P12814	2
+SKP1 component, POZ domain [IPR016073]	0.5121130551817075	0.1491925787403026	0.8814016757643057	1.0	0.9236606602187588	2	Q15369	1
+Nucleotidyl transferase domain [IPR005835]	0.5111036339165591	0.1473481544206262	0.8828572255151168	1.0	0.9247901104240503	2	Q9NR50	1
+Brix domain [IPR007109]	0.3809363422027604	0.142101535098117	0.8869998056499557	1.0	0.9287320462921692	5	Q9NQ55,Q96G21,Q9H7B2,Q9H9Y2	4
+Glycosyl hydrolase, family 13, catalytic domain [IPR006047]	0.5047106325706648	0.1360042731446492	0.8918179028750053	1.0	0.9317841341178033	2	P08195	1
+VHS domain [IPR002014]	0.4973082099596343	0.1235949736360821	0.9016359724293026	1.0	0.9368441682966608	2	O14964	1
+RuvB-like, AAA-lid domain [IPR041048]	0.4962987886944955	0.1219628429528349	0.902928445557639	1.0	0.9373913633270144	2	Q9Y230	1
+TIP49, P-loop domain [IPR010339]	0.4962987886944955	0.1219628429528349	0.902928445557639	1.0	0.9373913633270144	2	Q9Y230	1
+Clp ATPase, C-terminal [IPR019489]	0.4858681022880216	0.1059335427659474	0.915635080513528	1.0	0.9437788114093124	2	Q9H078	1
+Ribosomal protein S7 domain [IPR023798]	0.4791386271870929	0.0963914941038583	0.9232096473897082	1.0	0.949986219760406	2	Q9Y2R9	1
+Potassium channel tetramerisation-type BTB domain [IPR003131]	0.4761103633916705	0.0922988404793911	0.9264606096024146	1.0	0.9529309127339122	2	Q9NXV2	1
+EB1, C-terminal [IPR004953]	0.4680349932705308	0.0819850881222955	0.9346585714876544	1.0	0.9603135672058266	2	Q15691	1
+PTBP1, RNA recognition motif 2-like [IPR021790]	0.4735779198922841	0.0817883187982123	0.93481504520077	1.0	0.9603135672058266	3	Q8WVV9,P14866	2
+Zinc finger, C3HC4 RING-type [IPR018957]	0.3800821248663487	0.0707724130317079	0.9435788879658042	1.0	0.9671931656992232	4	Q9H000	1
+Malic enzyme, NAD-binding [IPR012302]	0.4576043068640729	0.0699220455081227	0.9442557062934394	1.0	0.9671931656992232	2	P48163	1
+Malic enzyme, N-terminal domain [IPR012301]	0.4576043068640729	0.0699220455081227	0.9442557062934394	1.0	0.9671931656992232	2	P48163	1
+Pyrroline-5-carboxylate reductase, dimerisation domain [IPR029036]	0.4516997643890905	0.0513039684128228	0.9590833059348356	1.0	0.9794893337206833	3	Q53H96,Q96C36	2
+Pyrroline-5-carboxylate reductase, catalytic, N-terminal [IPR028939]	0.4516997643890905	0.0513039684128228	0.9590833059348356	1.0	0.9794893337206833	3	Q53H96,Q96C36	2
+Zinc finger, ZZ-type [IPR000433]	0.4071332436069987	0.0293958424822943	0.9765488885919072	1.0	0.9931830823734892	2	Q13501	1
+JAB1/MPN/MOV34 metalloenzyme domain [IPR000555]	0.3223196223870553	0.0270549591646554	0.978415898976824	1.0	0.9946686547737814	8	O15372,Q7L5N1,O00303,O95630,Q92905,O00487,P51665	7
+Man1/Src1, C-terminal [IPR018996]	0.3997308209959614	0.0255749385201855	0.9795963756940338	1.0	0.995409805731866	2	Q9Y2U8	1
+Glycerol-3-phosphate acyltransferase-like, C-terminal domain [IPR045520]	0.3977119784656772	0.0246115524323411	0.980364804583141	1.0	0.995409805731866	2	O15228	1
+GPAT/DHAPAT, acyltransferase domain [IPR041728]	0.3977119784656772	0.0246115524323411	0.980364804583141	1.0	0.995409805731866	2	O15228	1
+Sec23/Sec24 beta-sandwich [IPR012990]	0.3180634617448405	0.0189420547208772	0.9848873307349746	1.0	0.996694578602405	6	Q15437	1
+Sec23/Sec24, helical domain [IPR006900]	0.3180634617448405	0.0189420547208772	0.9848873307349746	1.0	0.996694578602405	6	Q15437	1
+Zinc finger, Sec23/Sec24-type [IPR006895]	0.3180634617448405	0.0189420547208772	0.9848873307349746	1.0	0.996694578602405	6	Q15437	1
+Sec23/Sec24, trunk domain [IPR006896]	0.3180634617448405	0.0189420547208772	0.9848873307349746	1.0	0.996694578602405	6	Q15437	1
+Methylglyoxal synthase-like domain [IPR011607]	0.3660834454912477	0.0133057133808552	0.9893838899734456	1.0	1.0	2	P31939	1
+cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain [IPR003117]	0.3543068640645997	0.0105985171377972	0.9915437651214324	1.0	1.0	2	P10644	1
+Class II aldolase/adducin N-terminal [IPR001303]	0.3384925975773863	0.0079177189397194	0.993682640307458	1.0	1.0	2	Q9UEY8	1

interpro_family/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "Mitochondrial carrier protein [IPR002067]", "1": "Syntaxin [IPR045242]"}