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Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
Protein localization 0.6671642044328666 4.715581410560694 2.4102149633886683e-06 0.0032509086557688 0.0032562004155394 79 Q15388,O60830,O94826,O60220,P08574,O75381,O43681,Q9NS69,O14734,Q96B49,Q13190,Q9Y584,Q5JRX3,P09601,P56589,P21796,O14925,P51648,Q9NR77,P50402,P62072,Q10713,O43615,P34913,Q3ZCQ8,Q13505,O15254,Q13011,O75431,Q9Y512,Q8N4H5,Q15067,Q9NX63,P40855,P46379,O96008,O43808,Q9Y3D6,Q9Y5J9,Q9Y5Y5 40
Mitochondrial protein import 0.7134575208127256 3.411948674887576 0.0006450025650281 0.581751536756915 0.417457941367405 38 Q15388,O94826,O60830,O60220,P08574,Q9NS69,Q96B49,Q9Y584,Q5JRX3,P21796,O14925,P62072,Q10713,O43615,Q3ZCQ8,P12236,Q13505,O75431,Q9Y512,Q8N4H5,Q9NX63,O96008,Q9Y5J9 23
Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins 0.503327220338003 3.1126758434616195 0.0018539952984488 0.9184934926581804 0.417457941367405 69 O43819,P03886,P20674,P00846,Q9BQ95,P08574,O75880,Q9P0J0,P24539,P00403,Q9UDW1,O43676,O14949,P13073,Q9NX14,Q8IUX1,P14927,O43674,P31930,O14548,O75964,O75947,Q86Y39,P21912,O75306,P22695,Q9P032,O75438,O96000 29
Cristae formation 0.678774646482885 2.8911107194066066 0.0038388284974155 0.9944626399977006 0.5242322936653409 22 O75431,Q6UXV4,O75947,P00846,Q9Y512,Q9BUR5,O75964,Q13505,Q5XKP0,P24539,Q9NX63,Q9NVH1 12
Slc mediated transmembrane transport 0.66643482349091 2.8205859502435024 0.0047936030079427 0.9984840750702056 0.5242322936653409 24 P53985,Q8TB61,Q99808,Q9UPY5,P35613,O00400,Q70HW3,Q96QD8,P12236,Q8TAD4,Q9UBX3,Q9Y6M7,P30825,P08195 14
Mitochondrial calcium ion transport 0.7048733407273553 2.747325947125046 0.0060083390010012 0.9997088726488468 0.5242322936653409 18 P21796,P35232,O95202,Q10713,Q9UJZ1,Q99623,Q9H4I9,Q8WWC4,Q9BPX6,Q9Y277,Q8IYU8,P45880,Q8NE86 13
Insertion of tail anchored proteins into the endoplasmic reticulum membrane 0.8374244998202091 2.7430673815609827 0.0060868193987848 0.9997383288196584 0.5242322936653409 10 P46379,P51648,O43681,Q13190,P09601 5
Class i peroxisomal membrane protein import 0.7641163189127529 2.646758174835257 0.0081267444794872 0.9999836957978758 0.5242322936653409 12 P51648,Q9NR77,O43808,Q9Y3D6,P40855,Q9Y5Y5 6
Mitophagy 0.7597753584146479 2.6238121488619623 0.0086951727635575 0.9999924845396048 0.5242322936653409 12 P21796,Q15388,O94826,O96008,Q9NS69,Q8N4H5,P67870,Q96B49 8
Pink1 prkn mediated mitophagy 0.8100444252441247 2.4954963584665664 0.0125781046296375 0.9999999625700268 0.5242322936653409 9 P21796,Q15388,O94826,O96008,Q9NS69,Q8N4H5,Q96B49 7
Gpcr ligand binding 0.7854217261672596 2.4901607931185783 0.0127685314176697 0.9999999711559728 0.5242322936653409 10 P63218,P42892,Q9NRV9,Q9NZJ7,P07602 5
Metabolism of porphyrins 0.7759272211787023 2.4431572460513897 0.0145593920484334 0.9999999975183288 0.5242322936653409 10 P30519,P22830,P09601,Q7KZN9 4
Processing of smdt1 0.6982743495455581 2.3460705088029776 0.018972517996906 0.9999999999942288 0.5242322936653409 13 P35232,Q10713,Q9UJZ1,Q99623,Q9H4I9,Q8WWC4,Q9BPX6,Q8IYU8,Q8NE86 9
Sphingolipid de novo biosynthesis 0.7281039925984637 2.320875203708809 0.0202935801834387 0.9999999999990654 0.5242322936653409 11 P51648,O15269,O95470,Q96G23,Q8N5B7,Q06136 6
Peptide hormone metabolism 0.7011820165105745 2.3079787996745393 0.0210003156685265 0.9999999999996474 0.5242322936653409 12 O60645,P67812,P61009,Q15005,O75787,Q8TAD4 6
Peptide ligand binding receptors 0.8104568114563561 2.3036409668198607 0.0212428061803553 0.9999999999997478 0.5242322936653409 7 Q9NZJ7,Q9NRV9,P07602,P42892 4
Class a 1 rhodopsin like receptors 0.8104568114563561 2.3036409668198607 0.0212428061803553 0.9999999999997478 0.5242322936653409 7 Q9NZJ7,Q9NRV9,P07602,P42892 4
Cargo trafficking to the periciliary membrane 0.6450460854211084 2.2962861091497686 0.0216595278164646 0.999999999999858 0.5242322936653409 17 Q10713,O43924 2
Mitochondrial biogenesis 0.5795297915572997 2.2801945044200265 0.0225961551390587 0.9999999999999613 0.5263345791873862 32 O75431,Q6UXV4,O75947,P00846,Q9Y512,O00411,O75964,Q9BUR5,Q13505,Q5XKP0,P24539,Q9NX63,Q9NVH1 13
Respiratory electron transport 0.4792123226310814 2.2587737821805813 0.0238974601834043 0.9999999999999936 0.5384577914354961 57 O43819,P03886,P20674,Q9BQ95,O75880,Q9P0J0,P00403,Q9UDW1,O43676,O14949,P13073,Q9NX14,Q8IUX1,P14927,O43674,P31930,O14548,Q86Y39,P21912,O75306,P22695,Q9P032,O75438,O96000 24
Ire1alpha activates chaperones 0.5851947499943375 2.2585122212373525 0.0239137435130494 0.9999999999999936 0.5384577914354961 25 P49748,O76024,O43731,Q9NWM8,O95070,P43307 6
Transport of small molecules 0.499454486135231 2.214198975861992 0.0268150942959604 1.0 0.5456173498161366 152 Q8TB61,P63218,Q99436,P53680,P05023,P28070,P21281,Q9Y6B6,P30519,P09601,P45880,P56589,P30825,P08195,P21796,P20618,Q9BUN8,Q10713,Q9H0U3,O95202,P51790,Q8WWC4,O00400,P28072,P12236,P35610,Q9Y277,Q8TAD4,Q8WTV0,Q9H936,Q15904,Q8N4V1,Q93050,Q9UPY5,P16615,Q9UJZ1,P49721,Q9H4I9,O00231,Q9UNS2,P60900,Q9UL46,Q9UBV2,Q8IYU8,Q9UBX3,Q9HD20,P08183,P40855,Q9Y6M7,Q8NE86,O15118,Q99808,P53985,P35613,P07237,P51798,P28074,Q70HW3,Q92530,P10644,Q9BPX6,Q13546,Q96QD8 63
Transport of inorganic cations anions and amino acids oligopeptides 0.7068969004416944 2.2089218179568713 0.027180079356935 1.0 0.5456173498161366 11 Q9UPY5,Q9UBX3,Q70HW3,Q96QD8,Q9Y6M7,P30825,P08195 7
Sphingolipid metabolism 0.576342044605237 2.204878731799782 0.0274626053201312 1.0 0.5456173498161366 27 Q16880,P51648,O15269,P10619,O95470,Q16739,Q8N5B7,Q96G23,O43681,Q06136,Q9NZJ7,P07602 12
Cytoprotection by hmox1 0.4472807341596325 2.1817439990486207 0.0291284316929159 1.0 0.5465788805976891 61 O43819,P20674,Q8TCT9,Q99436,O75880,P28070,P30519,P09601,P00403,P28072,P13073,P60900,O00231,P49721,O14548,P67870,Q9UL46,Q92530,P28074 19
Cellular response to chemical stress 0.4248828823105653 2.1528156394033524 0.0313331705293873 1.0 0.5467819543571547 72 O43819,P20674,Q8TCT9,Q99436,O75880,P28070,P30519,P09601,P00403,P20618,P28072,P13073,Q99757,O00231,P49721,P60900,O14548,P67870,Q9UL46,Q8TED1,O00483,P07237,Q92530,P28074 24
Ddx58 ifih1 mediated induction of interferon alpha beta 0.6636385679157928 2.1503130289817296 0.0315304624943246 1.0 0.5467819543571547 13 O94826,Q13546,Q7Z434 3
Synaptic adhesion like molecules 0.8235085298536124 2.1019369917154864 0.0355587955901099 1.0 0.5776711093327774 6 O95197 1
Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps 0.6299841231874859 2.0669984137045856 0.0387343034315004 1.0 0.5776711093327774 15 P05067,Q02818,O76024,O43852,P07237,Q07065,P14625,Q06481 8
Formation of atp by chemiosmotic coupling 0.6554889915000659 2.053706915048907 0.0400040668710568 1.0 0.5776711093327774 12 P36542,O75947,P00846,P03928,O75964,P56385,P06576,P24539 8
Organelle biogenesis and maintenance 0.4258139346777469 2.0193574970551467 0.0434500757987241 1.0 0.5776711093327774 84 O95684,O43924,P00846,P56385,Q5XKP0,P24539,Q9NVH1,Q10713,Q13505,O75431,Q6UXV4,A6NIH7,Q9Y512,O00411,O75964,O75935,Q9NX63,O75947,Q9BUR5 19
Phase i functionalization of compounds 0.6376329711191535 2.000590087281674 0.0454365827195695 1.0 0.5776711093327774 13 P16435,O43169,P07099,Q16850 4
Cholesterol biosynthesis 0.6158384680317587 1.9810758058915616 0.0475827730523705 1.0 0.589764462328006 15 Q15392,Q9H2C2,Q9BWD1,Q16850,Q14739,Q15800,Q14534 7
The citric acid tca cycle and respiratory electron transport 0.4343682870882502 1.930132807213714 0.0535903844050971 1.0 0.5994363350272938 101 O43819,P03886,P20674,P00846,Q9BQ95,P08574,O75880,Q9P0J0,P24539,P00403,P21796,Q9UDW1,O43676,O14949,P13073,Q15118,Q9NX14,Q15120,Q8IUX1,P14927,O43674,P31930,O14548,O75964,P53985,Q86Y39,O75947,P35613,P21912,O75306,P22695,Q9P032,O75438,O96000 34
Synthesis of pg 0.903737496670102 1.893317945923262 0.0583156000200051 1.0 0.6203494143860389 4 Q8N2A8 1
Metabolism of folate and pterines 0.7040064723565345 1.88771367116613 0.0590644000309188 1.0 0.6234062847013387 8 Q9H2D1,P41440 2
Ras processing 0.8301798618191044 1.8580312368403065 0.0631645785619379 1.0 0.6484088712332869 5 O43924 1
Cell surface interactions at the vascular wall 0.6047472326076657 1.8578101812133057 0.0631959748084383 1.0 0.6484088712332869 14 P53985,P35613,P14174,Q92896,Q08722,P08195 6
Translation of sars cov 1 structural proteins 0.8279248080272952 1.8487971170187376 0.0644871138186871 1.0 0.6484088712332869 5 Q10472 1
Heme degradation 0.8905666875945876 1.843087738306876 0.0653162013065797 1.0 0.6484088712332869 4 P30519 1
Adora2b mediated anti inflammatory cytokines production 0.6884940294533959 1.8114798153768965 0.0700666107796348 1.0 0.6666196560794835 8 P04899,P63218,P63096 3
Peroxisomal lipid metabolism 0.6066074904256966 1.7741380616836653 0.0760403163541154 1.0 0.6988467169687754 12 O43808,P51648,Q15067,O15254 4
Heme biosynthesis 0.739297671876807 1.7333131362275744 0.0830400271920632 1.0 0.7145673677482642 6 P36551,P22830,Q7KZN9 3
Transport of vitamins nucleosides and related molecules 0.6677427343275756 1.7086304269238692 0.0875194288424623 1.0 0.7483465086466241 8 Q8TB61,O00400 2
G alpha i signalling events 0.508806150952219 1.6983128548358184 0.0894487297954058 1.0 0.7503846055649064 21 P04899,P63218,P63096,P52292,Q9NRV9,Q9NZJ7,P07602 7
Metabolism of steroid hormones 0.7273485572375796 1.679951348939693 0.0929667818853876 1.0 0.7612007413767194 6 Q53GQ0,P30536 2
Rac2 gtpase cycle 0.5043094487946325 1.6671526136028232 0.0954840624688562 1.0 0.7624157849873642 29 P50402,O15173,Q13505,Q86XL3,Q14739,P42167 6
G alpha s signalling events 0.7192064618369383 1.6434545091570556 0.1002889300613745 1.0 0.769831502914301 6 P63218,P63096 2
Ra biosynthesis pathway 0.773002767563498 1.6216337204918752 0.1048817980508045 1.0 0.7747519091898426 5 O94788,Q8NBN7 2
Amino acid transport across the plasma membrane 0.7718695649815898 1.6169040600297668 0.1058989918979522 1.0 0.7749635921131719 5 Q96QD8,P30825,P08195 3
Pre notch processing in golgi 0.8311628154891098 1.613996945571608 0.1065280888135986 1.0 0.7749635921131719 4 Q9UBV2 1
Protein protein interactions at synapses 0.5786436188242325 1.6109617081444352 0.1071880687280708 1.0 0.7749635921131719 12 O95197 1
Phospholipid metabolism 0.4804026824538171 1.6065773746840069 0.1081471090208807 1.0 0.7749635921131719 40 Q6P1A2,Q10713,Q96N66,Q8IY17,Q6UWP7,Q9UG56,Q8N2A8,Q9NPH0,Q8NCC3,Q8IV08,Q8N9F7,Q9NTJ5 12
Transport of bile salts and organic acids metal ions and amine compounds 0.8257145719725899 1.5927993148616808 0.1112052188964274 1.0 0.7837898798510737 4 P35613,P53985 2
Interleukin 4 and interleukin 13 signaling 0.5924616800734102 1.5815272377104528 0.1137575361561724 1.0 0.7837898798510737 11 P09601,P08670 2
Sars cov 1 infection 0.6083684164813675 1.5716529028493098 0.1160310702962359 1.0 0.7837898798510737 10 Q10472,P27824 2
Signaling by pdgfr in disease 0.8076575217321791 1.5223554892343345 0.1279200313097845 1.0 0.826555333201266 4 O43815 1
Synthesis of pips at the golgi membrane 0.7467193013365012 1.5115501334008 0.1306483457107896 1.0 0.826555333201266 5 Q10713 1
Glycosphingolipid metabolism 0.5307443255856646 1.5010720210761117 0.1333369345547541 1.0 0.826555333201266 16 Q16880,P10619,O43681,Q9NZJ7,P07602 5
Cytochrome p450 arranged by substrate type 0.9089563957793894 1.4966965087203754 0.1344722451263682 1.0 0.826555333201266 3 P16435 1
Abc family proteins mediated transport 0.4410753784617086 1.487909034903138 0.136774884667032 1.0 0.826555333201266 49 Q99436,Q9BUN8,P60900,O00231,P49721,Q92530,P28070,P28072,Q9UL46,P40855,Q9UBV2,P28074,P56589,P08183 14
Alpha oxidation of phytanate 0.797263217988194 1.4816864788784896 0.138423736455945 1.0 0.827479946690185 4 P51648 1
Negative regulators of ddx58 ifih1 signaling 0.6341474526824489 1.4709435365868573 0.1413063873675732 1.0 0.8373023216385592 7 Q7Z434 1
Rac3 gtpase cycle 0.4793269993272779 1.4639090011666775 0.1432188136639052 1.0 0.8449284596503753 27 P50402,Q9UQB8,O15173,Q14739,P42167 5
G alpha z signalling events 0.726308788797993 1.4255741409607556 0.1539913049546237 1.0 0.8632458630443847 5 P63218,P63096 2
Gaba receptor activation 0.726308788797993 1.4255741409607556 0.1539913049546237 1.0 0.8632458630443847 5 P63218,P63096 2
Gaba b receptor activation 0.726308788797993 1.4255741409607556 0.1539913049546237 1.0 0.8632458630443847 5 P63218,P63096 2
Adp signalling through p2y purinoceptor 12 0.726308788797993 1.4255741409607556 0.1539913049546237 1.0 0.8632458630443847 5 P63218,P63096 2
Signal amplification 0.6242105847280033 1.4221348508087 0.1549871072297279 1.0 0.864422259487073 7 P63218,P63096 2
Basigin interactions 0.6218396447755745 1.4104677498074474 0.1584016126836669 1.0 0.8680040524257333 7 P35613,P53985,P08195 3
Synthesis of very long chain fatty acyl coas 0.6656742735012066 1.4010832070192858 0.1611891926762876 1.0 0.8780911262325184 6 Q9P035,P33121,Q53GQ0 3
Glycerophospholipid biosynthesis 0.4681033290895819 1.3792215007086346 0.1678264708730856 1.0 0.9006148104315641 29 Q92604,Q6P1A2,Q9NQZ5,Q9UG56,P67870,Q8N2A8,Q8IV08,P48739,Q8NCC3,Q9NPH0,Q99943,Q6UWP7,Q96N66 13
Heparan sulfate heparin hs gag metabolism 0.71352960680123 1.371568771564298 0.1701977209344303 1.0 0.9052284734290892 5 P54802,P08236,Q7LGA3 3
Arachidonic acid metabolism 0.5976358689453294 1.3547585219178018 0.1754945056896879 1.0 0.9052284734290892 8 P34913,Q15165 2
Abc transporters in lipid homeostasis 0.8705509723689917 1.3516010454809475 0.1765029757006664 1.0 0.9052284734290892 3 P40855 1
Initiation of nuclear envelope ne reformation 0.4997236061975826 1.350388410687024 0.1768914263399552 1.0 0.9052284734290892 17 Q86XL3,P50402,P42167,Q14739 4
Insulin processing 0.6056057934314507 1.3303858674015347 0.1833911685495022 1.0 0.905747875764262 7 O60645,Q8TAD4 2
Selective autophagy 0.460168032962168 1.329266176597676 0.1837601690208095 1.0 0.905747875764262 32 P21796,Q15388,O94826,O96008,Q9NS69,Q96B49,P67870,Q8N4H5,P08670,Q8IWA4 10
Synthesis secretion and inactivation of glucagon like peptide 1 glp 1 0.7576544361944166 1.326117748514717 0.1848006980811616 1.0 0.905747875764262 4 P67812 1
Incretin synthesis secretion and inactivation 0.7576544361944166 1.326117748514717 0.1848006980811616 1.0 0.905747875764262 4 P67812 1
Adrenaline noradrenaline inhibits insulin secretion 0.7543423471782142 1.3130798214242567 0.1891560525469069 1.0 0.905747875764262 4 P63218,P63096 2
Pi metabolism 0.528050289369665 1.310925723642598 0.1898828591352346 1.0 0.905747875764262 12 Q10713,Q8IY17,Q9NTJ5 3
Glycosaminoglycan metabolism 0.5124938666237056 1.2894878666601777 0.1972285318387023 1.0 0.905747875764262 14 P54802,Q8NCH0,Q8TB61,Q7LGA3 4
Regulation of insulin secretion 0.5409920084203341 1.2886362880530706 0.197524561589756 1.0 0.905747875764262 11 P04899,P63218,P63096 3
Miscellaneous transport and binding events 0.6901360098262963 1.2724580399444327 0.2032104235492466 1.0 0.905747875764262 5 Q8N4V1 1
G1 s specific transcription 0.5669816433726053 1.2663448046487948 0.2053896625970623 1.0 0.905747875764262 9 Q9Y619 1
Translation of sars cov 2 structural proteins 0.5018401204623363 1.2643945657689173 0.2060884423956044 1.0 0.905747875764262 15 P46977,Q9H0U3,Q10472,P27824 4
Maturation of sars cov 2 spike protein 0.5364126814029015 1.2623791313910948 0.2068123947685074 1.0 0.905747875764262 11 P46977,Q9H0U3,P27824 3
Neuronal system 0.42654842999438 1.255111643866493 0.2094382341122331 1.0 0.905747875764262 46 P04899,P63218,P05091,P63096,O95197,P41440,P07196,P52292,O75915,P10644,P21964,Q96QD8,Q14012 13
Regulation of hmox1 expression and activity 0.4299464140322168 1.2374771408215852 0.2159099957079648 1.0 0.9236788706847636 44 Q8TCT9,Q99436,P60900,O00231,P49721,Q92530,P28070,P28072,P67870,Q9UL46,P09601,P28074 12
Attachment of gpi anchor to upar 0.681508044854884 1.2358538804814996 0.2165128827630673 1.0 0.9236788706847636 5 O43292,Q9H490 2
Sars cov 2 infection 0.4570461855083277 1.235262191527585 0.2167329400496447 1.0 0.9236788706847636 20 P46977,Q10472,Q9H0U3,Q9UQN3,P27824 5
Pregnenolone biosynthesis 0.7293590949792167 1.2146899456977538 0.2244843686911384 1.0 0.9354712764769508 4 P30536 1
Signaling by erbb4 0.624548485652274 1.212828381754646 0.2251954418391335 1.0 0.9354712764769508 6 P49768,P62993,Q92542 3
Response to elevated platelet cytosolic ca2 0.4437794202923998 1.183319191289316 0.2366826697278607 1.0 0.9514418953863092 29 Q9NUQ9,Q6UXV4,O43852,O94919,Q8NBX0,Q9NTK5,Q9NZJ7,Q96JJ7,P07602,Q06481 10
Integrin cell surface interactions 0.7209753842854371 1.181681034771544 0.2373322862658669 1.0 0.9514418953863092 4 P35613 1
Disorders of transmembrane transporters 0.3494567934826138 1.1728136493634256 0.2408705433061417 1.0 0.952024276245999 74 P53985,Q8NFH4,Q99436,Q9BUN8,P35613,P60900,O00231,P49721,O00400,P28070,P28072,Q92530,Q9BTX1,Q9UL46,Q9UBV2,P28074,P08195 17
Neurotransmitter release cycle 0.7183179253293324 1.1712216236461777 0.2415097056855637 1.0 0.952024276245999 4 Q96QD8 1
N glycan trimming in the er and calnexin calreticulin cycle 0.4925742829480301 1.1644338587134884 0.2442482328542383 1.0 0.952024276245999 14 Q9UBV2,Q9BUN8 2
Peroxisomal protein import 0.4360377312817893 1.1476334337851246 0.2511199215787361 1.0 0.961157493151772 21 P34913,O75381,O00116,O14734,Q15067,O15254,Q13011 7
G protein mediated events 0.5443630539782023 1.146135225073738 0.2517392045590108 1.0 0.961157493151772 9 P52292,P04899,P63096 3
Metabolism of lipids 0.4190263910270997 1.1309658670691138 0.2580694580894351 1.0 0.96312662397466 162 O95470,Q8IY17,O43681,O14734,P30536,Q9NZJ7,Q15800,Q15165,Q15392,Q9H2C2,P51648,P49748,P10619,Q10713,P34913,Q53GQ0,Q8N5B7,O43772,Q8NCC3,P35610,O15254,Q8N9F7,Q9NTJ5,Q14739,P07602,Q9UMR5,Q16880,P50897,Q14849,Q9BWD1,P23786,Q16739,Q9UG56,P38435,Q9NPH0,Q06136,Q15067,Q9NPJ6,O00767,Q6UWP7,Q96N66,Q9H7Z7,P37268,Q6P1A2,O43808,Q96G23,Q16850,Q8N2A8,O95864,Q8IV08,Q9P035,Q14534,Q8N8N7 53
Rhod gtpase cycle 0.4351725707940613 1.1225027673665977 0.2616487315739286 1.0 0.9678966164497632 24 P50402,O15173,Q8TAA9,Q14739,P42167 5
Aquaporin mediated transport 0.6534900284900225 1.1169827636039822 0.2640016950353163 1.0 0.9678966164497632 5 Q9UBI6,P63218,Q99797,P10644 4
Synthesis secretion and inactivation of glucose dependent insulinotropic polypeptide gip 0.8071889907842192 1.1128033276213152 0.2657929059462318 1.0 0.9678966164497632 3 P67812 1
Synthesis secretion and deacylation of ghrelin 0.8071889907842192 1.1128033276213152 0.2657929059462318 1.0 0.9678966164497632 3 P67812 1
Rhoa gtpase cycle 0.4268506987134143 1.091839747796873 0.2749035448216208 1.0 0.9829881994817876 37 P51572,P41440,O15173,Q13190,P30519,Q14739,P42167,Q8NBN3 8
Nf kb activation through fadd rip 1 pathway mediated by caspase 8 and 10 0.7997717787009564 1.085035409604485 0.2779059725389659 1.0 0.98747088896042 3 Q7Z434 1
Metabolism of cofactors 0.6450162334693055 1.0810784561397528 0.2796622157744322 1.0 0.98747088896042 5 P00374,P35270 2
Pyruvate metabolism 0.472118022274269 1.0729218977858797 0.2833061601322288 1.0 0.98747088896042 15 P21796,P35613,Q15120,Q15118 4
Calnexin calreticulin cycle 0.551926490835623 1.0641043221016804 0.2872814431296739 1.0 0.98747088896042 7 Q9UBV2 1
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane 0.6398811718117343 1.059342722873401 0.2894437246693755 1.0 0.98747088896042 5 Q99808,P12236,P36404 3
Adenylate cyclase inhibitory pathway 0.7909296733417497 1.0520182352832834 0.2927911833834504 1.0 0.9955212380664368 3 P63096 1
Gamma carboxylation hypusine formation and arylsulfatase activation 0.5263706010116074 1.0504477430014243 0.2935123049014101 1.0 0.9955212380664368 9 O60725,O43681 2
Anti inflammatory response favouring leishmania parasite infection 0.4841272110996403 1.0477562552653703 0.2947509217073092 1.0 0.9955212380664368 12 P04899,P63218,P63096 3
Hedgehog ligand biogenesis 0.4187823434546647 1.0457415230143778 0.2956803862248365 1.0 0.9961700792761948 39 Q99436,P60900,O00231,P49721,P07237,Q92530,P28070,P28072,Q9UL46,Q9UBV2,P28074 11
Unfolded protein response upr 0.4186062199541049 1.0315527060159269 0.3022817054587587 1.0 1.0 38 P49748,O76024,O43731,Q9NWM8,O95070,P43307 6
Fatty acid metabolism 0.38448441326861 1.020276228587255 0.3075974739527747 1.0 1.0 52 P50897,P51648,P49748,Q9H7Z7,Q9P035,Q8N8N7,P23786,O43808,P34913,Q53GQ0,O43772,O95864,Q15067,O15254,O00767,Q15165 16
Cdt1 association with the cdc6 orc origin complex 0.4185469387231179 1.0198988701580185 0.3077764254528567 1.0 1.0 37 Q99436,P60900,Q9Y619,O00231,P49721,Q92530,P28070,P28072,Q9UL46,P28074 10
Notch3 activation and transmission of signal to the nucleus 0.6796012815948859 1.019294147056311 0.3080633418281193 1.0 1.0 4 P49768,P67809,Q92542 3
Platelet activation signaling and aggregation 0.3830099229154027 1.0050025151154351 0.3148956387793704 1.0 1.0 52 Q9NUQ9,P63218,P04899,P63096,Q6UXV4,O43852,P18031,O94919,Q8NBX0,Q9NTK5,Q8N2K0,Q8NCG7,Q9NZJ7,Q96JJ7,P07602,Q06481 16
Tetrahydrobiopterin bh4 synthesis recycling salvage and regulation 0.7767730771666197 0.9993839371479046 0.3176087380482308 1.0 1.0 3 P00374 1
Beta oxidation of pristanoyl coa 0.6744301727658041 0.9991045082154948 0.317744067492347 1.0 1.0 4 O15254 1
Transmission across chemical synapses 0.4163618537643241 0.9914669848905984 0.3214576058017764 1.0 1.0 36 P04899,P63218,P05091,P63096,P07196,P52292,O75915,P10644,P21964,Q96QD8,Q14012 11
Nuclear signaling by erbb4 0.671695565542043 0.9884414404056924 0.3229365005816618 1.0 1.0 4 P49768,Q92542 2
Rab geranylgeranylation 0.4155450152592869 0.98232605826111 0.3259392408531454 1.0 1.0 22 P62820,Q9BZG1,P61026,P61019,Q15907,Q9UL25,Q969Q5 7
Vasopressin regulates renal water homeostasis via aquaporins 0.6682857511008572 0.9751598378630943 0.3294809805727463 1.0 1.0 4 P63218,P10644 2
Glucagon signaling in metabolic regulation 0.6682857511008572 0.9751598378630943 0.3294809805727463 1.0 1.0 4 P63218,P10644 2
Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein 0.4673944484194887 0.9747117929322308 0.3297032415454923 1.0 1.0 13 Q86YN1,P10619 2
Iron uptake and transport 0.4362860431056538 0.9669877775465402 0.3335501437733663 1.0 1.0 18 P30519 1
Defective cftr causes cystic fibrosis 0.4057777820170275 0.9584246467508696 0.3378486719031324 1.0 1.0 41 Q99436,Q9BUN8,P60900,O00231,P49721,Q92530,P28070,P28072,Q9UL46,Q9UBV2,P28074 11
Abc transporter disorders 0.4057777820170275 0.9584246467508696 0.3378486719031324 1.0 1.0 41 Q99436,Q9BUN8,P60900,O00231,P49721,Q92530,P28070,P28072,Q9UL46,Q9UBV2,P28074 11
Alpha linolenic omega3 and linoleic omega6 acid metabolism 0.5285534121408993 0.9482492246580853 0.3430025930433489 1.0 1.0 7 Q15067,O95864,O14734 3
Rhog gtpase cycle 0.4099547663431678 0.922688986617827 0.3561693068796105 1.0 1.0 34 P50402,O15173,Q13190,Q96JJ3,Q8TAA9,Q86XL3,Q14739,P42167 8
Notch4 activation and transmission of signal to the nucleus 0.752656464957906 0.9105316273581868 0.3625422100496658 1.0 1.0 3 P49768 1
Glutamate neurotransmitter release cycle 0.7473186236216696 0.8910329852166466 0.3729114746888464 1.0 1.0 3 Q96QD8 1
Proton coupled monocarboxylate transport 0.8744219139096441 0.8839154129973805 0.3767418763070034 1.0 1.0 2 P35613 1
Glucagon like peptide 1 glp1 regulates insulin secretion 0.595952409043583 0.8746682410052652 0.3817544452903298 1.0 1.0 5 P63218,P10644 2
Cilium assembly 0.3702124227214143 0.8727200776798713 0.3828156713631929 1.0 1.0 52 Q10713,A6NIH7,O43924 3
Cargo concentration in the er 0.4347683111672775 0.8686785632507814 0.3850229697312433 1.0 1.0 16 Q12907,P49755,Q13190,O75396,Q9Y6B6,Q96PC5 6
Stimuli sensing channels 0.5022538613900023 0.8663250134607688 0.3863119528805849 1.0 1.0 8 P51790,P51798,Q13546 3
Egr2 and sox10 mediated initiation of schwann cell myelination 0.5922509649625725 0.8592616189594667 0.3901961943014527 1.0 1.0 5 Q9NR77 1
Synthesis of bile acids and bile salts 0.6375934496261996 0.8565056950060309 0.3917181241077874 1.0 1.0 4 P51659,O14734,P22307 3
Bile acid and bile salt metabolism 0.6375934496261996 0.8565056950060309 0.3917181241077874 1.0 1.0 4 P51659,O14734,P22307 3
Noncanonical activation of notch3 0.73772241992883 0.8561572556182002 0.3919108022500726 1.0 1.0 3 P49768,Q92542 2
Activated notch1 transmits signal to the nucleus 0.7368771280342034 0.853096851436664 0.3936055973262933 1.0 1.0 3 P49768 1
Collagen biosynthesis and modifying enzymes 0.4643967332958202 0.8496994515831658 0.3954922034232124 1.0 1.0 11 P07237,P13674 2
Hs gag degradation 0.7316725978647701 0.8342977814064753 0.4041132017422466 1.0 1.0 3 P54802,P08236 2
Signaling by notch 0.3445956186748786 0.824230224701145 0.4098087563730226 1.0 1.0 58 Q99436,P16615,O00231,P49721,P60900,Q92542,Q92530,P28070,P49768,P28072,Q9UL46,Q9UBV2,P28074,Q8NBL1 14
Diseases associated with n glycosylation of proteins 0.6165086475728553 0.776243391051766 0.4376052904894192 1.0 1.0 4 Q9BT22 1
Glycerophospholipid catabolism 0.8431163287086456 0.77578474448687 0.4378760929505887 1.0 1.0 2 Q8IY17 1
Class b 2 secretin family receptors 0.7148616677664847 0.7741386045522992 0.4388488303870739 1.0 1.0 3 P63218 1
Acyl chain remodeling of cl 0.7142918586282769 0.7721157848630996 0.4400458540237593 1.0 1.0 3 Q6UWP7 1
Intra golgi traffic 0.448874308316691 0.7620638921327665 0.4460218719803264 1.0 1.0 11 O00461,Q13190,Q8TBA6,P54920 4
Miro gtpase cycle 0.6120934619633215 0.759602136566218 0.4474924416314734 1.0 1.0 4 Q8IWA4 1
Extra nuclear estrogen signaling 0.4290723703664716 0.7423397668280025 0.4578815036214334 1.0 1.0 13 O43815,P63218,P63096 3
Complex i biogenesis 0.3889663118507074 0.7415857749526642 0.4583383448240061 1.0 1.0 32 P03886,O43676,Q9BQ95,Q8IUX1,Q86Y39,O43674,O75306,Q9P032,Q9P0J0,O96000,Q9NX14 11
Intra golgi and retrograde golgi to er traffic 0.3205414417837687 0.7402447172650739 0.4591515185837158 1.0 1.0 79 Q10472,P24390,Q9P2W9,O43731,Q12981,Q7Z6M1,P40616,O15260,O75935,Q13190,Q8TBA6,O00461,P62820,Q9Y3B3 14
Synthesis of substrates in n glycan biosythesis 0.4531285297297426 0.721108902445764 0.47084251415323 1.0 1.0 10 Q86YN1 1
Notch2 activation and transmission of signal to the nucleus 0.8246175738171495 0.7135697346362858 0.47549327790869 1.0 1.0 2 P49768 1
Regulated proteolysis of p75ntr 0.8246175738171495 0.7135697346362858 0.47549327790869 1.0 1.0 2 P49768 1
Nrif signals cell death from the nucleus 0.8246175738171495 0.7135697346362858 0.47549327790869 1.0 1.0 2 P49768 1
Signaling by notch2 0.8246175738171495 0.7135697346362858 0.47549327790869 1.0 1.0 2 P49768 1
Post translational modification synthesis of gpi anchored proteins 0.5125272498879259 0.7042240607054648 0.4812932493071113 1.0 1.0 6 O43292,Q9H490 2
Neurotransmitter clearance 0.821415866239777 0.7029477273222283 0.4820883261437632 1.0 1.0 2 P21964 1
Mastl facilitates mitotic progression 0.5099255543963347 0.692773114421933 0.4884519470325976 1.0 1.0 6 Q96GX5 1
Synthesis of pa 0.4675023450470028 0.691741000125701 0.4890999941460401 1.0 1.0 8 Q8N2A8,Q9NPH0 2
Plasma lipoprotein assembly 0.8100320170757777 0.6655601139608673 0.5056923078906705 1.0 1.0 2 P07237 1
Chylomicron assembly 0.8100320170757777 0.6655601139608673 0.5056923078906705 1.0 1.0 2 P07237 1
Signaling by gpcr 0.3778696418198402 0.6594178536603738 0.509627480476222 1.0 1.0 35 P04899,P63218,P63096,P52292,P42892,Q9BYT8,Q9NRV9,Q8N2K0,Q9NZJ7,Q8NCG7,P07602 11
Sars cov infections 0.3400692933522451 0.6576347638462241 0.5107728505951799 1.0 1.0 55 P46977,Q10472,P53680,P04843,Q9H0U3,P05023,Q9UQN3,Q02790,Q99720,P21964,Q13546,P27824,P62942 13
Orc1 removal from chromatin 0.3612964601793073 0.6546115290183983 0.5127178993276313 1.0 1.0 47 Q99436,P60900,Q9Y619,O00231,P49721,Q92530,P28070,P28072,Q9UL46,P28074 10
E2f mediated regulation of dna replication 0.4566467334947913 0.6382854609961502 0.5232878744869032 1.0 1.0 8 Q9Y619 1
Signaling by hedgehog 0.3469007129593016 0.6347510020956159 0.5255908242954572 1.0 1.0 52 Q99436,P60900,O00231,P49721,P07237,Q92530,P28070,P28072,Q9UL46,P10644,Q9UBV2,P28074 12
Unwinding of dna 0.4454350927246873 0.6275153164009879 0.5303214994575987 1.0 1.0 9 P33993,Q9BRX5,Q9BRT9,P25205,Q14566,P33992,P33991,P49736 8
Organic anion transporters 0.7950907150480321 0.6174556237870513 0.5369342427767534 1.0 1.0 2 Q9UBX3 1
Downstream signaling events of b cell receptor bcr 0.3673424475800258 0.6056559679099534 0.544743228903446 1.0 1.0 40 Q99436,P60900,O00231,P49721,Q92530,P28070,P28072,Q9UL46,P28074,P62942 10
Linoleic acid la metabolism 0.7890430451796558 0.5983213812048197 0.5496255126948033 1.0 1.0 2 O95864 1
Opioid signalling 0.392842926054204 0.5978682118239387 0.5499278719550662 1.0 1.0 16 P04899,P63218,P63096,P52292,P10644,P30154 6
Beta oxidation of very long chain fatty acids 0.5257751206953096 0.5903397793593995 0.5549628752906359 1.0 1.0 5 Q15067 1
Rac1 gtpase cycle 0.3692245544701662 0.5823361015462821 0.5603403128376265 1.0 1.0 32 Q9UQB8,P50402,P42167,Q14739 4
Mucopolysaccharidoses 0.5627251198852912 0.578818246899877 0.5627118176753134 1.0 1.0 4 P54802,P08236 2
Signaling by type 1 insulin like growth factor 1 receptor igf1r 0.6569330119833446 0.575465911071987 0.5649762389316593 1.0 1.0 3 P62993 1
Collagen formation 0.4028977173407925 0.5715423335987168 0.5676320725503157 1.0 1.0 12 P07237,P13674 2
Biological oxidations 0.3659851766154097 0.5709260960349472 0.5680497405748341 1.0 1.0 37 Q8TB61,Q16850,O43169,P07099,P16435 5
Regulation of pten stability and activity 0.3643295538013107 0.5709190477539132 0.568054518546496 1.0 1.0 39 Q99436,P60900,O00231,P49721,Q92530,P28070,P28072,P67870,Q9UL46,P28074 10
Activation of kainate receptors upon glutamate binding 0.6514426135272499 0.5575129653555031 0.5771770031907997 1.0 1.0 3 P63218 1
Ripk1 mediated regulated necrosis 0.4111249243933044 0.5545765844635118 0.5791843088148334 1.0 1.0 11 P41440 1
Sulfur amino acid metabolism 0.429317037505682 0.5469577020224112 0.5844077918997743 1.0 1.0 9 Q9UBX3 1
Chk1 chk2 cds1 mediated inactivation of cyclin b cdk1 complex 0.4276034236804561 0.5385134890603845 0.5902225950790605 1.0 1.0 9 P14635,P62258,Q04917,P61981,P06493,P31946,P63104,Q9Y3B8 8
Ub specific processing proteases 0.3030783470653789 0.5274559813586517 0.5978769768421155 1.0 1.0 62 P21796,Q15388,O94826,Q99436,P60900,O00231,P49721,Q92530,P28070,P28072,Q13546,Q9UL46,Q9Y277,P45880,P28074 15
Signaling by retinoic acid 0.3892245255506655 0.5274118518863671 0.597907614908769 1.0 1.0 14 O94788,Q15120,Q15118,Q8NBN7 4
Synthesis of bile acids and bile salts via 7alpha hydroxycholesterol 0.6419928825622824 0.5270428894893038 0.5981638048242863 1.0 1.0 3 O14734,P22307 2
Thromboxane signalling through tp receptor 0.6416034823294574 0.5257993934077775 0.5990275960509268 1.0 1.0 3 P63218 1
Degradation of axin 0.3601313715317559 0.5178837845516377 0.6045393563205415 1.0 1.0 36 Q99436,P60900,O00231,P49721,Q92530,P28070,P28072,Q9UL46,P28074 9
Regulation of runx3 expression and activity 0.3601313715317559 0.5178837845516377 0.6045393563205415 1.0 1.0 36 Q99436,P60900,O00231,P49721,Q92530,P28070,P28072,Q9UL46,P28074 9
Cross presentation of soluble exogenous antigens endosomes 0.3601313715317559 0.5178837845516377 0.6045393563205415 1.0 1.0 36 Q99436,P60900,O00231,P49721,Q92530,P28070,P28072,Q9UL46,P28074 9
Signaling by the b cell receptor bcr 0.3545674387617918 0.5162507088048727 0.6056793178264599 1.0 1.0 42 P20618,Q99436,P60900,O00231,P49721,P61289,Q92530,P28070,P28072,Q9UL46,P28074,P62942 12
Metabolism of polyamines 0.3586118401815399 0.5157521294184847 0.6060275407065314 1.0 1.0 38 Q99436,P60900,O00231,P49721,Q92530,P28070,P28072,Q9UL46,P28074 9
Stabilization of p53 0.3591116349728566 0.5141519945980362 0.6071457277296086 1.0 1.0 37 Q99436,P60900,O00231,P49721,Q92530,P28070,P28072,Q9UL46,P28074 9
Pre notch expression and processing 0.3999160004024652 0.4952362681099399 0.6204333522994259 1.0 1.0 11 Q9UBV2,P16615 2
Switching of origins to a post replicative state 0.3311578802078763 0.478437574603431 0.6323387953879225 1.0 1.0 52 Q99436,P60900,Q9Y619,O00231,P49721,Q92530,P28070,P28072,Q9UL46,P28074 10
Cargo recognition for clathrin mediated endocytosis 0.3551088656423044 0.4775928903862288 0.632939992102584 1.0 1.0 29 O14656,O14657,Q9BT78,P53680,Q99627,P62993,Q9UNS2,P61201,Q9UBC2,Q14108,Q96D71,Q9UBW8 12
Flt3 signaling in disease 0.5329298682805231 0.4760012841350693 0.6340734630522378 1.0 1.0 4 Q14789,P62993,Q01082 3
Activation of bad and translocation to mitochondria 0.4272986457590806 0.4656062133642178 0.641497394692323 1.0 1.0 7 P62258,Q04917,P61981,P31946,P63104,Q9Y3B8 6
Signaling by notch4 0.3468956235820737 0.4613555682002525 0.6445435235664672 1.0 1.0 43 Q99436,P60900,O00231,P49721,Q92542,Q92530,P28070,P49768,P28072,Q9UL46,P28074 11
G1 s dna damage checkpoints 0.3512245255087651 0.4549866659976143 0.6491188316714482 1.0 1.0 38 Q99436,P60900,O00231,P49721,Q92530,P28070,P28072,Q9UL46,P28074 9
Trna modification in the nucleus and cytosol 0.401627273053641 0.4546007581731542 0.6493964892232651 1.0 1.0 10 Q5VV42,Q9NPF4,O75648 3
Aflatoxin activation and detoxification 0.6167124636803729 0.4484711533746057 0.6538132003015298 1.0 1.0 3 O14880 1
Inwardly rectifying k channels 0.7356812522234144 0.4393822515843249 0.6603845846039607 1.0 1.0 2 P63218 1
Presynaptic function of kainate receptors 0.7356812522234144 0.4393822515843249 0.6603845846039607 1.0 1.0 2 P63218 1
Prostacyclin signalling through prostacyclin receptor 0.7356812522234144 0.4393822515843249 0.6603845846039607 1.0 1.0 2 P63218 1
G protein activation 0.7356812522234144 0.4393822515843249 0.6603845846039607 1.0 1.0 2 P63218 1
Glucagon type ligand receptors 0.7356812522234144 0.4393822515843249 0.6603845846039607 1.0 1.0 2 P63218 1
Potassium channels 0.7356812522234144 0.4393822515843249 0.6603845846039607 1.0 1.0 2 P63218 1
Ca2 pathway 0.5210385438036754 0.436697168847871 0.6623309827355166 1.0 1.0 4 Q9UBI6,P63218 2
G beta gamma signalling through cdc42 0.6127483272354945 0.4365746245455589 0.6624198688386276 1.0 1.0 3 P63218 1
Foxo mediated transcription 0.4128342245989206 0.4311011990540324 0.6663947888304556 1.0 1.0 8 P61981,P31946,P27348,P63104,P04179,Q92769,Q9Y3B8 7
Negative regulation of nmda receptor mediated neuronal transmission 0.4832010605878998 0.4306605839940199 0.6667151827008484 1.0 1.0 5 P07196 1
Dna damage recognition in gg ner 0.3722223367163768 0.4298906135146011 0.6672752137670106 1.0 1.0 14 Q13620,Q9BT78,Q99627,Q9UNS2,P41208,Q9UBW8 6
Synthesis of pc 0.5108817809115166 0.4040227240366949 0.6861960089763679 1.0 1.0 4 P67870 1
Signaling by flt3 fusion proteins 0.5999999999999984 0.399167229691618 0.6897699877554766 1.0 1.0 3 Q14789,P62993 2
Constitutive signaling by overexpressed erbb2 0.5962657872309888 0.388465808086567 0.6976713523921712 1.0 1.0 3 P62993 1
Mitotic g1 phase and g1 s transition 0.2845019242875007 0.3849504470176518 0.7002741291626726 1.0 1.0 71 P20618,P49643,Q99436,P60900,Q9Y619,O00231,P49721,P00374,P61289,P28070,P28072,P33991,P31350,Q92530,Q9UL46,P28074 16
Metabolism of steroids 0.3410274289874522 0.3844610886762224 0.700636730650166 1.0 1.0 40 Q15392,Q9H2C2,P37268,Q14849,Q9BWD1,Q53GQ0,Q16850,P38435,P30536,O00767,Q14534,Q15800,Q14739 13
Autophagy 0.3296045347345006 0.3806351891203444 0.70347396627063 1.0 1.0 48 P21796,Q15388,O94826,O96008,Q9NS69,Q9UQN3,Q96B49,P67870,Q8N4H5,P08670 10
O linked glycosylation of mucins 0.50198720908455 0.3761406638005651 0.7068123249580092 1.0 1.0 4 Q10472 1
O linked glycosylation 0.5019872090845499 0.3761406638005645 0.7068123249580096 1.0 1.0 4 Q10472 1
Cellular response to hypoxia 0.340954816993881 0.3723506696901936 0.7096317773764629 1.0 1.0 38 Q99436,P60900,O00231,P49721,Q92530,P28070,P28072,Q9UL46,P28074 9
Signal regulatory protein family interactions 0.497840302506747 0.3633877546227723 0.7163152478919654 1.0 1.0 4 Q08722 1
Plasma lipoprotein clearance 0.3622506147525082 0.3623480286811568 0.7170919714412085 1.0 1.0 13 P35610 1
Piwi interacting rna pirna biogenesis 0.3890074710401432 0.3563170321540096 0.7216031554667157 1.0 1.0 9 Q8N2A8 1
Degradation of dvl 0.3392529755847898 0.3550041963450744 0.7225864475047146 1.0 1.0 37 Q99436,P60900,O00231,P49721,Q92530,P28070,P28072,Q9UL46,P28074 9
Regulation of ras by gaps 0.3392529755847898 0.3550041963450744 0.7225864475047146 1.0 1.0 37 Q99436,P60900,O00231,P49721,Q92530,P28070,P28072,Q9UL46,P28074 9
Acyl chain remodelling of ps 0.7011739594450437 0.3478997022548954 0.7279155088879783 1.0 1.0 2 Q6P1A2 1
Activation of bh3 only proteins 0.3745986443096752 0.3259537350833043 0.7444593591211874 1.0 1.0 10 P62258,Q04917,P61981,P63167,P04637,P31946,P27348,P63104,Q9Y3B8 9
Activation of the pre replicative complex 0.3398096172311919 0.3231723100918425 0.7465647500501873 1.0 1.0 18 Q9Y619 1
Nuclear envelope ne reassembly 0.3241332366328196 0.3169418552884706 0.7512877220375809 1.0 1.0 47 P50402,Q9UQN3,Q8IXJ6,Q9BTX1,Q86XL3,Q14739,P42167 7
Degradation of gli1 by the proteasome 0.3332858283459646 0.316717148057448 0.7514582358898421 1.0 1.0 39 Q99436,P60900,O00231,P49721,Q92530,P28070,P28072,Q9UL46,P28074 9
Antigen presentation folding assembly and peptide loading of class i mhc 0.3449878510260521 0.3107466543005353 0.7559932268294884 1.0 1.0 16 P51572,Q9NZ08 2
Depolymerisation of the nuclear lamina 0.3783599555066516 0.309376412710867 0.7570352108069345 1.0 1.0 9 P42167 1
Downregulation of erbb2 signaling 0.4713421146315454 0.2859292431127658 0.7749323155781658 1.0 1.0 4 P07900,Q9UNE7,Q16543 3
Negative regulation of notch4 signaling 0.3286317092912844 0.2856560492281697 0.7751415701733306 1.0 1.0 40 Q99436,P60900,O00231,P49721,Q92530,P28070,P28072,Q9UL46,P28074 9
Small interfering rna sirna biogenesis 0.6723585912486731 0.2796211555339232 0.7797681745396519 1.0 1.0 2 Q15631 1
Plasma lipoprotein assembly remodeling and clearance 0.3373928969181994 0.2688389118114336 0.7880536479779217 1.0 1.0 16 Q8WTV0,P35610 2
Transcriptional regulation by runx3 0.3255111193135492 0.2614968525023188 0.7937093764447152 1.0 1.0 40 Q99436,P60900,O00231,P49721,Q92530,P28070,P28072,Q9UL46,P28074 9
Hedgehog off state 0.3171449715799925 0.2575651463526944 0.7967425314790804 1.0 1.0 47 Q99436,P60900,O00231,P49721,Q92530,P28070,P28072,Q9UL46,P10644,P28074 10
Dag and ip3 signaling 0.4005048738505702 0.2560045255247365 0.7979473428732313 1.0 1.0 6 P52292 1
Detoxification of reactive oxygen species 0.3506068917496531 0.2542067598848864 0.7993358284771468 1.0 1.0 11 Q8TED1 1
Adp signalling through p2y purinoceptor 1 0.5422171687234116 0.2482571427114356 0.803935456316571 1.0 1.0 3 P63218 1
The role of gtse1 in g2 m progression after g2 checkpoint 0.3140953726418858 0.2455771316325322 0.8060095935133953 1.0 1.0 48 Q99436,P60900,O00231,P49721,Q92530,P28070,P28072,Q9UL46,P28074 9
Regulation of localization of foxo transcription factors 0.4269943019943086 0.245397118808225 0.8061489596820459 1.0 1.0 5 P31946,Q9Y3B8,P61981,P63104 4
Rhof gtpase cycle 0.3353269859095291 0.244406319091281 0.8069161482288285 1.0 1.0 15 Q8TAA9,P42167 2
Cdc42 gtpase cycle 0.3132287606827603 0.2443888642515214 0.8069296653959503 1.0 1.0 21 Q9UQB8,Q14739,P42167 3
Regulation of pyruvate dehydrogenase pdh complex 0.3683349079352661 0.2424463773293902 0.8084343021372198 1.0 1.0 8 Q15118 1
Pka activation in glucagon signalling 0.6527926004980515 0.2378789080603779 0.8119750149337897 1.0 1.0 2 P10644 1
Pka mediated phosphorylation of creb 0.6527926004980515 0.2378789080603779 0.8119750149337897 1.0 1.0 2 P10644 1
Creb1 phosphorylation through the activation of adenylate cyclase 0.6527926004980515 0.2378789080603779 0.8119750149337897 1.0 1.0 2 P10644 1
Regulation of runx2 expression and activity 0.3211310971864415 0.2334531926975867 0.8154095122120781 1.0 1.0 41 Q99436,P60900,O00231,P49721,Q92530,P28070,P28072,Q9UL46,P28074 9
Rhoc gtpase cycle 0.315011459382393 0.2262956329155236 0.8209714947319744 1.0 1.0 24 Q13190,Q14739,P42167,P41440 4
Ethanol oxidation 0.5278317451336039 0.2160653384288035 0.8289368174727751 1.0 1.0 3 P30837 1
Antigen processing cross presentation 0.3086127085486668 0.2138646853986244 0.8306525800357678 1.0 1.0 49 P20618,Q12846,Q99436,P60900,O00231,P49721,P61289,Q92530,P28070,P28072,Q9UIQ6,Q9UL46,P28074 13
Diseases of glycosylation 0.3268231311307051 0.2127489517848353 0.831522782685755 1.0 1.0 16 Q8NCH0,P10619 2
Cyclin a cdk2 associated events at s phase entry 0.3174747397969203 0.2057103584796442 0.8370171667139319 1.0 1.0 41 Q99436,P60900,O00231,P49721,Q92530,P28070,P28072,Q9UL46,P28074 9
Scf skp2 mediated degradation of p27 p21 0.3174747397969203 0.2057103584796442 0.8370171667139319 1.0 1.0 41 Q99436,P60900,O00231,P49721,Q92530,P28070,P28072,Q9UL46,P28074 9
Regulation of lipid metabolism by pparalpha 0.3308907514014066 0.2038679181382516 0.8384567161624492 1.0 1.0 12 P23786,Q15067,Q9NPJ6 3
Polymerase switching on the c strand of the telomere 0.3379131046146369 0.1991956085686701 0.8421097344457815 1.0 1.0 11 P41440 1
Polymerase switching 0.3379131046146369 0.1991956085686701 0.8421097344457815 1.0 1.0 11 P41440 1
Slc transporter disorders 0.3180456701767787 0.1973218141566162 0.8435757096961187 1.0 1.0 33 Q9BTX1,O00400 2
Golgi to er retrograde transport 0.2660775617578645 0.1938478598931359 0.8462950109405121 1.0 1.0 64 Q10472,P24390,Q9P2W9,O43731,Q12981,O15260,O75935,P62820,Q9Y3B3 9
Hedgehog on state 0.3162206149825268 0.1915433118759186 0.8480999506858058 1.0 1.0 40 Q99436,P60900,O00231,P49721,Q92530,P28070,P28072,Q9UL46,P28074 9
Synthesis of dna 0.270274448513234 0.1894337820881523 0.8497528494919309 1.0 1.0 74 P49643,Q99436,P41440,P60900,Q9Y619,O00231,P49721,Q92530,P28070,P28072,Q9UL46,P28074 12
Leishmania infection 0.3166429787926658 0.1853336461253847 0.8529673493425938 1.0 1.0 36 Q9UQB8,P09601,P63218,P63096 4
Trna modification in the mitochondrion 0.4049512990800508 0.1833493001136157 0.8545239540726624 1.0 1.0 5 O75648 1
Recognition of dna damage by pcna containing replication complex 0.3175670900042258 0.1783008762064828 0.858486690726797 1.0 1.0 17 P41440 1
Auf1 hnrnp d0 binds and destabilizes mrna 0.3130290905274587 0.1726647061693211 0.8629149874485076 1.0 1.0 41 Q99436,P60900,O00231,P49721,Q92530,P28070,P28072,Q9UL46,P28074 9
Metabolism of fat soluble vitamins 0.5062230428280269 0.1721550863289825 0.8633156065432099 1.0 1.0 3 Q8N0U8 1
Tysnd1 cleaves peroxisomal proteins 0.3985252231457444 0.1665716716170303 0.8677070850205406 1.0 1.0 5 Q15067 1
Receptor mediated mitophagy 0.5010664092230548 0.1624866625184428 0.8709226304767719 1.0 1.0 3 P67870 1
Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1 0.3088309286177862 0.1603571307448277 0.8725997572578836 1.0 1.0 44 Q99436,P60900,O00231,P49721,Q92530,P28070,P28072,Q9UL46,P28074 9
Platelet calcium homeostasis 0.4194884501896283 0.1577160711565483 0.8746805360432612 1.0 1.0 4 P16615 1
Reduction of cytosolic ca levels 0.4194884501896283 0.1577160711565483 0.8746805360432612 1.0 1.0 4 P16615 1
Signaling by notch3 0.3692162260643917 0.1569527958699244 0.875282050351641 1.0 1.0 6 P49768,P67809,Q92542 3
Hemostasis 0.2991072725035243 0.1533142260292282 0.8781504825536202 1.0 1.0 111 Q9NUQ9,P63218,Q8NBX0,Q9NTK5,Q9UIJ7,Q9NZJ7,Q8IWA4,Q06481,P08195,P60903,P63096,O43852,P07602,P04899,P42785,Q6UXV4,Q9UPY5,P16615,P14174,Q8N2K0,Q08722,P53985,P35613,O94919,Q92896,P10644,Q96JJ7,Q8NCG7 28
Ovarian tumor domain proteases 0.3383862969935098 0.15055673450486 0.8803253931122788 1.0 1.0 9 Q7Z434 1
Egfr downregulation 0.3911292560038985 0.1480308810197971 0.8823183971883679 1.0 1.0 5 Q9UBC2 1
Synthesis of prostaglandins pg and thromboxanes tx 0.4124689007742712 0.1430216225158785 0.8862731044449879 1.0 1.0 4 Q9H7Z7,Q8N8N7 2
Asymmetric localization of pcp proteins 0.310313434183479 0.1421624422453244 0.8869516971717497 1.0 1.0 37 Q99436,P60900,O00231,P49721,Q92530,P28070,P28072,Q9UL46,P28074 9
Vxpx cargo targeting to cilium 0.3629027117123765 0.1389210120359683 0.8895125667625776 1.0 1.0 6 O60645 1
Uch proteinases 0.3068610813490348 0.1328864888895499 0.8942831524363481 1.0 1.0 42 Q99436,P60900,O00231,P49721,Q92530,P28070,P28072,Q9UL46,P28074 9
Ras activation upon ca2 influx through nmda receptor 0.4073692545727738 0.1327675398962581 0.8943772264557008 1.0 1.0 4 Q14168,P07196 2
Long term potentiation 0.4073692545727738 0.1327675398962581 0.8943772264557008 1.0 1.0 4 Q14168,P07196 2
Unblocking of nmda receptors glutamate binding and activation 0.4073692545727738 0.1327675398962581 0.8943772264557008 1.0 1.0 4 Q14168,P07196 2
Tcr signaling 0.3044588955149425 0.1277505930962571 0.8983463505758391 1.0 1.0 44 Q99436,P60900,O00231,P49721,Q92530,P28070,P28072,Q9UL46,P28074 9
Cooperation of pdcl phlp1 and tric cct in g protein beta folding 0.3123835231071057 0.126387337676485 0.8994253248466932 1.0 1.0 12 Q9UBI6,P67870,P63218 3
Dna replication pre initiation 0.2748225883752524 0.1189491335442309 0.9053156551124744 1.0 1.0 59 P49643,Q99436,P60900,Q9Y619,O00231,P49721,Q92530,P28070,P28072,Q9UL46,P28074 11
Ca dependent events 0.3783271074407904 0.1179395485834507 0.9061155566723784 1.0 1.0 5 P52292 1
Copi dependent golgi to er retrograde traffic 0.3041537403595479 0.1091513635627534 0.9130824359881502 1.0 1.0 41 P24390,Q9P2W9,O43731,Q12981,O15260,P62820 6
Deubiquitination 0.2645348275207955 0.108454570344818 0.913635115493336 1.0 1.0 76 P21796,Q15388,O94826,Q99436,P60900,O00231,P49721,Q92530,P28070,P28072,Q13546,Q7Z434,Q9Y277,P45880 14
Degradation of the extracellular matrix 0.328374211797198 0.101547849220135 0.9191155756529464 1.0 1.0 8 P35613,P49768 2
Ion homeostasis 0.3180634248677887 0.0988332670230774 0.921270654528498 1.0 1.0 10 P16615,Q12797,P05023,P23634 4
Cardiac conduction 0.3180634248677887 0.0988332670230774 0.921270654528498 1.0 1.0 10 P16615,Q12797,P05023,P23634 4
Nicotinate metabolism 0.3890076557399484 0.0988236919108288 0.9212782571442903 1.0 1.0 4 P43490 1
Regulation of runx1 expression and activity 0.4597864768683297 0.0965359690546265 0.9230949081397606 1.0 1.0 3 Q9HCE1,Q06124 2
Signaling by egfr 0.3258467023172877 0.0937502591101465 0.9253075450558956 1.0 1.0 8 Q06124,Q99961,P62993,Q9UBC2,P60953,P19174,P41240 7
Platelet homeostasis 0.3036667349852523 0.093116978721334 0.925810628971594 1.0 1.0 12 P30154,P16615,P63218,P23634 4
Neddylation 0.2528713225027618 0.0921775319325889 0.9265569889535424 1.0 1.0 65 Q9BT78,Q99436,P28070,Q9UBW8,P20618,Q99627,P28072,Q13564,P61962,P60900,O00231,P49721,Q9UNS2,Q9UL46,Q9H0A8,Q13620,P61289,Q92530,Q9BW61,P28074 20
Mapk6 mapk4 signaling 0.2972652666995539 0.0905159937575491 0.9278771849431382 1.0 1.0 46 P20618,Q99436,P60900,O00231,P49721,Q92530,P28070,P28072,Q16181,Q9UL46,P28074 11
Signaling by ptk6 0.3149235929308766 0.0883308932681852 0.9296136856355166 1.0 1.0 10 Q96JJ3,P23246 2
Neurotransmitter receptors and postsynaptic signal transmission 0.2990006775724078 0.0853405894273347 0.93199062351931 1.0 1.0 30 P04899,P63218,P63096,P07196,P52292,P10644,Q14012 7
Regulated necrosis 0.2960203905526193 0.0833207846224248 0.9335964740175942 1.0 1.0 18 Q13546,P41440 2
Tnfr2 non canonical nf kb pathway 0.3006786605715135 0.082194602255851 0.9344919656990665 1.0 1.0 40 Q99436,P60900,O00231,P49721,Q92530,P28070,P28072,Q9UL46,P28074 9
Dectin 1 mediated noncanonical nf kb signaling 0.3006786605715135 0.082194602255851 0.9344919656990665 1.0 1.0 40 Q99436,P60900,O00231,P49721,Q92530,P28070,P28072,Q9UL46,P28074 9
Runx1 regulates transcription of genes involved in differentiation of hscs 0.2998589387150563 0.0746472221225129 0.9404954010844022 1.0 1.0 39 Q99436,P60900,O00231,P49721,Q92530,P28070,P28072,Q9UL46,P28074 9
Rrna processing in the mitochondrion 0.3730865076539751 0.0731864967450944 0.9416577116072188 1.0 1.0 4 Q7L0Y3,Q9BQ52,O15091 3
Trna processing in the mitochondrion 0.3730865076539751 0.0731864967450944 0.9416577116072188 1.0 1.0 4 Q7L0Y3,Q9BQ52,O15091 3
Pd 1 signaling 0.5325506937033211 0.0687603224627753 0.94518040138962 1.0 1.0 2 P41240 1
Cd28 co stimulation 0.3543447293447291 0.0686301547014077 0.9452840154687284 1.0 1.0 5 P42345,Q13177,P62993,P60953 4
Phosphorylation of emi1 0.4309608540925126 0.0623200319442714 0.9503079762970292 1.0 1.0 3 P53350,P06493 2
Purine salvage 0.3507950569599699 0.0621274305445175 0.9504613527714962 1.0 1.0 5 P00813 1
Pp2a mediated dephosphorylation of key metabolic factors 0.4185053380782884 0.0503629936224774 0.9598331257551644 1.0 1.0 3 P30154,P30153 2
Regulation of glycolysis by fructose 2 6 bisphosphate metabolism 0.4185053380782884 0.0503629936224774 0.9598331257551644 1.0 1.0 3 P30154,P30153 2
Amyloid fiber formation 0.3128106076397032 0.0485742583369374 0.961258584613346 1.0 1.0 7 Q9UJY4,Q9Y287 2
Signaling by scf kit 0.3542185831256723 0.0473150618746974 0.9622621238872088 1.0 1.0 4 Q06124,P42224,P62993 3
Cd28 dependent vav1 pathway 0.3542185831256721 0.0473150618746974 0.9622621238872088 1.0 1.0 4 Q13177,P60953,P62993 3
Foxo mediated transcription of oxidative stress metabolic and neuronal genes 0.4120996441281143 0.0448373489292425 0.964236954875274 1.0 1.0 3 P04179,Q92769 2
Beta oxidation of lauroyl coa to decanoyl coa coa 0.3492898470808614 0.0413431207803244 0.9670223570275038 1.0 1.0 4 Q16836 1
Beta oxidation of hexanoyl coa to butanoyl coa 0.3492898470808614 0.0413431207803244 0.9670223570275038 1.0 1.0 4 Q16836 1
Signaling by notch1 pest domain mutants in cancer 0.3097325313677541 0.0407639551323412 0.9674840750975447 1.0 1.0 7 P49768 1
Conversion from apc c cdc20 to apc c cdh1 in late anaphase 0.3373562072711351 0.0393694003790962 0.9685958759476364 1.0 1.0 5 Q9UJX4,Q9UJX3 2
Signaling by ntrk3 trkc 0.3458646198726792 0.0373798699913362 0.970182122872138 1.0 1.0 4 Q8WX92 1
Signaling by erbb2 in cancer 0.3442506229975169 0.0355648771535549 0.9716293145648672 1.0 1.0 4 Q16543,P62993,P07900 3
Constitutive signaling by egfrviii 0.3442506229975169 0.0355648771535549 0.9716293145648672 1.0 1.0 4 Q16543,P62993,P07900 3
Signaling by erbb2 ecd mutants 0.3442506229975169 0.0355648771535549 0.9716293145648672 1.0 1.0 4 Q16543,P62993,P07900 3
Constitutive signaling by ligand responsive egfr cancer variants 0.3442506229975169 0.0355648771535549 0.9716293145648672 1.0 1.0 4 Q16543,P62993,P07900 3
Signaling by egfr in cancer 0.3442506229975169 0.0355648771535549 0.9716293145648672 1.0 1.0 4 Q16543,P62993,P07900 3
Fcgr3a mediated il10 synthesis 0.3442506229975153 0.035564877153553 0.9716293145648688 1.0 1.0 4 P13861,O43865,P10644 3
Arms mediated activation 0.4621131270010825 0.030395686341933 0.9757514850683032 1.0 1.0 2 P46108 1
Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects 0.3761565836298898 0.0209262412625371 0.9833044937046528 1.0 1.0 3 Q00534,P11802 2
Beta oxidation of butanoyl coa to acetyl coa 0.3736923091685513 0.0196846082626484 0.9842949692291698 1.0 1.0 3 Q16836 1
Transcription of e2f targets under negative control by p107 rbl1 and p130 rbl2 in complex with hdac1 0.4119530416222156 0.0195645850793344 0.9843907154351228 1.0 1.0 2 P06493 1
Mrna editing 0.405549626467462 0.018782241823574 0.985014820297038 1.0 1.0 2 Q9NRW3 1
Ptk6 regulates cell cycle 0.3760227676983436 0.0163062351220716 0.986990083295455 1.0 1.0 2 P11802 1
Signaling by fgfr4 in disease 0.3440056919245934 0.0150350496613496 0.9880042179525308 1.0 1.0 2 P62993 1
Ecm proteoglycans 0.3191035218783462 0.0145992160539745 0.9883519246850284 1.0 1.0 2 P05067 1
Dap12 signaling 0.3441281138790119 0.0080564546993525 0.9935719487176656 1.0 1.0 3 P63000,P62993 2
Fceri mediated ca 2 mobilization 0.3441281138790108 0.008056454699352 0.993571948717666 1.0 1.0 3 O43865,P62993 2
Downstream signaling of activated fgfr4 0.3441281138790083 0.0080564546993511 0.9935719487176666 1.0 1.0 3 Q06124,P62993 2
Downstream signaling of activated fgfr3 0.3441281138790083 0.0080564546993511 0.9935719487176666 1.0 1.0 3 Q06124,P62993 2
Downstream signaling of activated fgfr2 0.3441281138790083 0.0080564546993511 0.9935719487176666 1.0 1.0 3 Q06124,P62993 2
Downstream signaling of activated fgfr1 0.3441281138790083 0.0080564546993511 0.9935719487176666 1.0 1.0 3 Q06124,P62993 2
Ion transport by p type atpases 0.2824852268429302 0.0060677403952768 0.9951586733272364 1.0 1.0 11 Q9HD20,P16615 2
Lysine catabolism 0.2947909312916807 0.0058895410173244 0.9953008533183874 1.0 1.0 7 Q9BQT8,P36957 2
Ret signaling 0.3118547525809955 0.0058642837918947 0.995321005320597 1.0 1.0 4 Q06124,P19174,P62993 3
Signalling to ras 0.3277580071174442 0.0038025251279734 0.9969660312197856 1.0 1.0 3 P11233,P62993 2
Metalloprotease dubs 0.3252669039145981 0.0032666465381516 0.9973935977970868 1.0 1.0 3 Q9NXR7,O00487 2