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Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
Ras processing 0.8631189973726869 2.0882740090388285 0.0367731245933429 1.0 1.0 5 O43924,P49356 2
Carnitine metabolism 0.8261900584660868 1.943118116747401 0.0520018885519224 1.0 1.0 5 O43772 1
Transport of inorganic cations anions and amino acids oligopeptides 0.7709075609932612 1.8301778537042024 0.067223348253447 1.0 1.0 7 Q96QD8,Q9UBX3,Q70HW3 3
Regulation of mecp2 expression and activity 0.765743695297589 1.7909496587917504 0.0733013737511789 1.0 1.0 8 Q14739 1
Interleukin 20 family signaling 0.9082780981621982 1.7888156215233233 0.0736445142663755 1.0 1.0 3 Q06124 1
Interleukin 6 family signaling 0.9082780981621982 1.7888156215233233 0.0736445142663755 1.0 1.0 3 Q06124 1
Interleukin 6 signaling 0.9082780981621982 1.7888156215233233 0.0736445142663755 1.0 1.0 3 Q06124 1
Metabolism of fat soluble vitamins 0.8092687259759247 1.7516832722968958 0.0798282848060996 1.0 1.0 4 Q8N0U8 1
Nr1h2 and nr1h3 mediated signaling 0.8069219207648245 1.7425134665874975 0.0814186371315135 1.0 1.0 4 Q8NB78 1
Class a 1 rhodopsin like receptors 0.7453857884310631 1.7421644643663332 0.0814796701136568 1.0 1.0 6 P42892,P07602 2
Peptide ligand binding receptors 0.7453857884310631 1.7421644643663332 0.0814796701136568 1.0 1.0 6 P42892,P07602 2
Metabolism of folate and pterines 0.7506904962369442 1.710673581936698 0.0871413871599515 1.0 1.0 9 Q9H2D1,P00374 2
Pink1 prkn mediated mitophagy 0.7384846851580176 1.695352264009932 0.0900086157424859 1.0 1.0 7 Q9NS69,P21796,Q15388 3
Trna modification in the nucleus and cytosol 0.7423790111687896 1.693774223616754 0.0903081939908303 1.0 1.0 8 Q9H974,O60294 2
Egr2 and sox10 mediated initiation of schwann cell myelination 0.7293034053766692 1.674810395849066 0.0939714385314949 1.0 1.0 6 Q9NR77,Q16850 2
Alk mutants bind tkis 0.7272812155309566 1.6663114337316884 0.0956514005819979 1.0 1.0 6 O43815,P10644 2
Endosomal vacuolar pathway 0.8741290272026327 1.6601083841785456 0.0968926505529987 1.0 1.0 3 Q9UIQ6 1
Binding and uptake of ligands by scavenger receptors 0.7302398177785989 1.6429378097387315 0.1003958011326511 1.0 1.0 8 Q8WTV0,Q07954 2
Formation of the cornified envelope 0.7435846778029084 1.610670590354114 0.1072515390409365 1.0 1.0 5 P07384,Q14126 2
Keratinization 0.7435846778029084 1.610670590354114 0.1072515390409365 1.0 1.0 5 P07384,Q14126 2
Downstream signal transduction 0.7115029623786492 1.5997771001611985 0.1096480406897395 1.0 1.0 6 P42224,Q06124 2
Signaling by pdgf 0.7115029623786492 1.5997771001611985 0.1096480406897395 1.0 1.0 6 P42224,Q06124 2
Regulation of runx1 expression and activity 0.8564788562757071 1.5932036801377256 0.1111145059223808 1.0 1.0 3 Q06124 1
Apoptotic cleavage of cell adhesion proteins 0.73689150113437 1.5833130362871768 0.1133501330703032 1.0 1.0 5 Q07157,Q14126 2
Mitophagy 0.7193299206781621 1.5616944576501228 0.1183599850823364 1.0 1.0 10 Q9NS69,Q8N4H5,P21796,O96008,P19784,Q15388,P67870 7
Stimuli sensing channels 0.7101304679051712 1.5582322495055438 0.1191782027410295 1.0 1.0 8 P51790 1
Glutamate neurotransmitter release cycle 0.7590133760004283 1.5539231007030825 0.120202760712853 1.0 1.0 4 Q96QD8 1
Synthesis of pc 0.7585985147162977 1.5522794693459798 0.1205953681875675 1.0 1.0 4 P35790 1
Immunoregulatory interactions between a lymphoid and a non lymphoid cell 0.7277137111403843 1.5457112947378469 0.1221743082454449 1.0 1.0 5 P10321,Q5KU26 2
Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps 0.7299813988918807 1.536857714617671 0.1243281564146139 1.0 1.0 14 Q9BTY2,O43852,Q15293,O76024 4
Constitutive signaling by aberrant pi3k in cancer 0.7255008161318866 1.536630227116886 0.1243838860985135 1.0 1.0 5 Q06124 1
Gpcr ligand binding 0.7035066665106323 1.5302044896650475 0.1259661204228941 1.0 1.0 8 P42892,P07602 2
Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux 0.8397244063393939 1.5294965692873408 0.1261413889047986 1.0 1.0 3 Q8NB78 1
Regulation of ifng signaling 0.8292597200859785 1.4896244654818904 0.1363230054285293 1.0 1.0 3 Q06124 1
Regulation of ifna signaling 0.8292597200859785 1.4896244654818904 0.1363230054285293 1.0 1.0 3 Q06124 1
Carboxyterminal post translational modifications of tubulin 0.6810919662626682 1.4705114439237603 0.141423288557128 1.0 1.0 6 Q13885,Q14166,P04350,Q9BUF5 4
Neurotransmitter release cycle 0.6825659150037705 1.4589578630354934 0.1445767055927671 1.0 1.0 7 Q96QD8 1
Pi3k akt signaling in cancer 0.6780589503629186 1.439720225939689 0.1499465686719483 1.0 1.0 7 Q06124 1
Synaptic adhesion like molecules 0.67050140334415 1.4252107248064716 0.1540962970922204 1.0 1.0 6 P41440,O95197 2
Amino acid transport across the plasma membrane 0.810628947895703 1.4185207269578075 0.1560387917129437 1.0 1.0 3 Q96QD8 1
Cholesterol biosynthesis 0.7023760277633526 1.4037589082758797 0.1603906540809718 1.0 1.0 15 Q9UBM7,Q14739,Q15392,Q16850 4
Signal regulatory protein family interactions 0.718613356184259 1.393203960205045 0.1635581225680427 1.0 1.0 4 Q06124 1
Mitochondrial fatty acid beta oxidation of unsaturated fatty acids 0.7182574452836574 1.3917831307167332 0.163988079788321 1.0 1.0 4 P11310 1
Cytosolic sulfonation of small molecules 0.7049357037992275 1.3385579891172077 0.1807146103172019 1.0 1.0 4 Q06520 1
Interferon gamma signaling 0.6599310976674091 1.3269486617005644 0.184525665706444 1.0 1.0 9 P04439,P10321,P42224,P19474,Q06124 5
Rnd1 gtpase cycle 0.6703674616194912 1.3195021813321164 0.1870012813531201 1.0 1.0 12 O75976,Q9Y2U8,Q15058,P51648,P02786,Q9NNW5,O43396 7
Synthesis of very long chain fatty acyl coas 0.6494907441235019 1.3172739530112905 0.1877468128077333 1.0 1.0 7 Q9NZ01 1
Gap junction assembly 0.67207074428887 1.315929515962075 0.1881977009524607 1.0 1.0 5 Q9BVA1,Q13885,P04350,Q9BUF5 4
Activation of ampk downstream of nmdars 0.67207074428887 1.315929515962075 0.1881977009524607 1.0 1.0 5 Q9BVA1,Q13885,P04350,Q9BUF5 4
Transport of connexons to the plasma membrane 0.67207074428887 1.315929515962075 0.1881977009524607 1.0 1.0 5 Q9BVA1,Q13885,P04350,Q9BUF5 4
Interferon alpha beta signaling 0.6486469053619289 1.296067077083434 0.1949523764108947 1.0 1.0 8 P04439,P10321,P42224,Q9Y3Z3,Q06124 5
Maturation of sars cov 2 spike protein 0.6502360223459742 1.2854183772980046 0.198646122705564 1.0 1.0 9 Q13724 1
Heme biosynthesis 0.6639864192477815 1.2823553706766824 0.1997180123757758 1.0 1.0 5 P22830 1
Receptor type tyrosine protein phosphatases 0.9297018770702984 1.2809281807486637 0.2002188933948017 1.0 1.0 2 Q13136 1
Resolution of d loop structures 0.660484251955122 1.267802090258058 0.2048686355506681 1.0 1.0 5 P38398,Q9UQ84 2
Resolution of d loop structures through synthesis dependent strand annealing sdsa 0.660484251955122 1.267802090258058 0.2048686355506681 1.0 1.0 5 P38398,Q9UQ84 2
Collagen biosynthesis and modifying enzymes 0.6425648116051943 1.2525126106009865 0.2103831361109649 1.0 1.0 9 O75718,P13674,Q32P28 3
Slc mediated transmembrane transport 0.666394451896647 1.23479726352979 0.2169059660697279 1.0 1.0 16 Q8TB61,Q15043,Q96QD8,Q9UBX3,Q70HW3 5
Flt3 signaling in disease 0.67824999991436 1.2317826344242049 0.2180302919086498 1.0 1.0 4 Q14789,Q06124 2
Notch3 activation and transmission of signal to the nucleus 0.7582871840723177 1.2185120126782918 0.2230294626253099 1.0 1.0 3 Q9Y6A5 1
Metabolism of porphyrins 0.6276837310562335 1.1885963028540576 0.2345985634367524 1.0 1.0 9 P09601,P22830,P30519 3
Signaling by scf kit 0.6144025769935901 1.1834906692694251 0.2366147423001421 1.0 1.0 6 Q06124 1
Heme degradation 0.6642039752900715 1.1755778975719695 0.2397635920580623 1.0 1.0 4 P30519 1
O linked glycosylation 0.7461280944724629 1.1721433716322929 0.2411394993273092 1.0 1.0 3 O43505 1
O linked glycosylation of mucins 0.7461280944724629 1.1721433716322929 0.2411394993273092 1.0 1.0 3 O43505 1
Signaling by notch3 0.6364508006536148 1.167853252078537 0.2428659635340437 1.0 1.0 5 P42224,Q9Y6A5 2
Dap12 interactions 0.744845360824743 1.1672567393196036 0.2431067033984515 1.0 1.0 3 P10321,P62993 2
Tysnd1 cleaves peroxisomal proteins 0.6310972786032627 1.1455868763602697 0.2519661299525229 1.0 1.0 5 O00116 1
Ptk6 regulates proteins involved in rna processing 0.7377369795242674 1.140198303645861 0.2542036940753638 1.0 1.0 3 Q07666 1
Signaling by csf3 g csf 0.6031524835609341 1.1348105358062233 0.2564547108626673 1.0 1.0 6 Q06124 1
Mucopolysaccharidoses 0.7346753554943047 1.1285563064590496 0.2590850514862128 1.0 1.0 3 P15586 1
Transcriptional regulation by mecp2 0.621271725823561 1.1268718548156602 0.2597966646904197 1.0 1.0 11 Q14739 1
Visual phototransduction 0.5978115981482331 1.1116964774563756 0.2662686748822307 1.0 1.0 6 P49356 1
Fatty acyl coa biosynthesis 0.626539655177824 1.0989537259283582 0.2717882504072721 1.0 1.0 14 Q9P035,Q9UMR5,P50897,Q9NZ01 4
Protein protein interactions at synapses 0.6123109442594794 1.0550132061764883 0.2914192849279029 1.0 1.0 13 P10586,O95197,Q13136,P41440 4
Signaling by kit in disease 0.7046688046949915 1.0149825222843727 0.3101141589064382 1.0 1.0 3 P42224 1
Signaling by pdgfra transmembrane juxtamembrane and kinase domain mutants 0.7046688046949915 1.0149825222843727 0.3101141589064382 1.0 1.0 3 P42224 1
Interleukin 2 family signaling 0.7046688046949915 1.0149825222843727 0.3101141589064382 1.0 1.0 3 P42224 1
Glycosaminoglycan metabolism 0.5948057419274374 1.0136478193202023 0.3107508311959099 1.0 1.0 11 Q8TB61,P15586,O43505,Q8NCH0,Q9UHD1,P16278 6
Miscellaneous transport and binding events 0.6991899852724603 0.9943770022840722 0.320039360140504 1.0 1.0 3 P35611,Q9UEY8 2
Transferrin endocytosis and recycling 0.580222209635693 0.9514444078684158 0.3413788263858892 1.0 1.0 11 Q15904,P02786,Q93050 3
Signalling to ras 0.6837260677466874 0.9365059192496072 0.3490127663583666 1.0 1.0 3 P11233,P62993 2
Activation of rac1 0.6820333414246805 0.9301999825037484 0.3522675509594664 1.0 1.0 3 O94813 1
G1 s specific transcription 0.5694821999150592 0.9221992787355108 0.3564246392505001 1.0 1.0 10 P00374 1
Aquaporin mediated transport 0.5762001386171298 0.9182721127120772 0.358476423403564 1.0 1.0 5 P10644 1
Sialic acid metabolism 0.596667130625203 0.9073444739926262 0.3642246625327905 1.0 1.0 4 P10619 1
Transport of vitamins nucleosides and related molecules 0.545941493918044 0.8879779746913812 0.3745525990690515 1.0 1.0 6 P12236,Q8TB61 2
Ca2 pathway 0.5913641333586191 0.8865703624819926 0.375310256226153 1.0 1.0 4 P35222,Q9HCE1 2
Transcriptional regulation by ventx 0.5574148384649142 0.8709265199633461 0.3837942754552736 1.0 1.0 10 Q9H1A4,P35222,Q9HCE1 3
Sphingolipid de novo biosynthesis 0.5556267257297783 0.8633504588377156 0.3879448090306643 1.0 1.0 10 Q06136,O15270,Q96G23 3
Receptor mediated mitophagy 0.6638438880706933 0.8628597252475978 0.3882145965919004 1.0 1.0 3 P67870,P19784 2
Collagen formation 0.5587079814156238 0.8601689728251888 0.3896959052836271 1.0 1.0 11 O75718,P13674,Q32P28 3
Interleukin 3 interleukin 5 and gm csf signaling 0.5381796727888428 0.8547770915549995 0.3926745627368175 1.0 1.0 6 P46108,Q06124 2
Aberrant regulation of mitotic exit in cancer due to rb1 defects 0.5379995577602233 0.8540080305594593 0.3931005398418901 1.0 1.0 6 Q9H1A4 1
Conversion from apc c cdc20 to apc c cdh1 in late anaphase 0.5379995577602233 0.8540080305594593 0.3931005398418901 1.0 1.0 6 Q9H1A4 1
Diseases of mitotic cell cycle 0.5482934458326889 0.8485541204957864 0.3961294454403927 1.0 1.0 9 Q9H1A4 1
Pkmts methylate histone lysines 0.5527371731542643 0.8189882299210532 0.4127931289214332 1.0 1.0 12 Q03164,Q9H7B4 2
Activation of gene expression by srebf srebp 0.5499360735922307 0.7758006530525433 0.4378666983118711 1.0 1.0 14 Q9UBM7 1
Glycosphingolipid metabolism 0.5525655421980122 0.7711653407392643 0.4406089349884359 1.0 1.0 15 Q16739,P10619,A0FGR8,P17900,Q13510,P07602,P16278,P06280 8
Mrna capping 0.5298323903526945 0.7707218796997047 0.4408718002451974 1.0 1.0 9 P19387,P18074 2
Sumoylation of transcription factors 0.638438880706923 0.7703672586596623 0.4410820695063018 1.0 1.0 3 P04637,Q12888 2
Rnd3 gtpase cycle 0.5478764142254796 0.7672596972379778 0.442927125656444 1.0 1.0 14 O75976,Q9Y2U8,Q07065,Q9NNW5,O43396 5
Cargo trafficking to the periciliary membrane 0.562780701521571 0.7671890787462815 0.4429691052674742 1.0 1.0 18 A6NIH7 1
Signaling by type 1 insulin like growth factor 1 receptor igf1r 0.5595429740532214 0.7634766775974903 0.4451791661845672 1.0 1.0 4 Q06124 1
Rna polymerase iii transcription initiation from type 1 promoter 0.5151822729767572 0.7572037605180575 0.4489277976157051 1.0 1.0 6 P62875,Q9Y5Q8 2
Keratan sulfate keratin metabolism 0.5364081029596658 0.756571564903066 0.4493065823411291 1.0 1.0 5 P15586,P16278,O43505 3
Signaling by pdgfr in disease 0.5342340764593358 0.747867011354743 0.4545403773238154 1.0 1.0 5 O43815 1
Abc transporters in lipid homeostasis 0.7810084652189944 0.7418829491442057 0.4581582574428144 1.0 1.0 2 P40855 1
Adenylate cyclase inhibitory pathway 0.6303429310198605 0.7413568660764334 0.4584770905281154 1.0 1.0 3 P04899 1
Retrograde transport at the trans golgi network 0.5441857559724479 0.7365952823312756 0.4613685047480698 1.0 1.0 15 P20645,P11717,Q5VIR6,Q7Z6M1 4
Translation of sars cov 2 structural proteins 0.5395554198270586 0.7328838521182173 0.4636292727330691 1.0 1.0 14 Q10472,Q13724,P46977 3
G protein mediated events 0.5204739300616226 0.7316269765892838 0.464396278102773 1.0 1.0 9 P10644 1
Netrin 1 signaling 0.5119793612417182 0.7277894375046627 0.4667424913035849 1.0 1.0 7 Q06124 1
Signaling by cytosolic fgfr1 fusion mutants 0.5060511322497538 0.7188842457912494 0.4722122441062195 1.0 1.0 6 O15164,P42224 2
Piwi interacting rna pirna biogenesis 0.5086000216064344 0.7136887613675124 0.4754196574178377 1.0 1.0 7 Q9Y2W6,P19387 2
Synthesis of pg 0.7725432462274597 0.7131196230966124 0.4757717377202524 1.0 1.0 2 Q8IV08 1
Vitamin d calciferol metabolism 0.7721751932278278 0.7118763212246983 0.4765413661618731 1.0 1.0 2 P38435 1
Gamma carboxylation hypusine formation and arylsulfatase activation 0.5091937935149369 0.7004505761667653 0.4836459604657035 1.0 1.0 8 Q9BU89,Q9HA64,O60725 3
Cell surface interactions at the vascular wall 0.5161635030196141 0.6981663342360727 0.48507317774345 1.0 1.0 10 Q08722,Q92896,Q06124 3
N glycan trimming in the er and calnexin calreticulin cycle 0.5308643278815114 0.6972236962165594 0.4856628116279962 1.0 1.0 14 Q13724,Q04323,Q9BUN8 3
Regulation of signaling by cbl 0.6169521888854129 0.6939537527688907 0.4877112121819613 1.0 1.0 3 P46108 1
Diseases of dna repair 0.5032519230444424 0.6758906064864987 0.4991101021516155 1.0 1.0 8 P38398,Q9UQ84 2
Negative regulation of the pi3k akt network 0.5144680176543099 0.6758300171816007 0.4991485742575448 1.0 1.0 11 Q06124 1
Ion channel transport 0.5572945578107106 0.6707242010229695 0.5023962426913526 1.0 1.0 23 Q15904,P51790,Q9C0H2,Q9HD20,Q93050 5
Interaction between l1 and ankyrins 0.5328633959533533 0.6630370277580109 0.5073068397421685 1.0 1.0 4 Q12955,O15020 2
Adora2b mediated anti inflammatory cytokines production 0.4985682259481468 0.6566336992261803 0.511416474950819 1.0 1.0 8 P10644 1
Rnd2 gtpase cycle 0.514546717334963 0.6459332342340334 0.5183225952676231 1.0 1.0 13 Q9Y2U8,Q15058,P51648,P02786,Q07065,Q9NNW5,O43396 7
Metabolism of cofactors 0.5083621016804101 0.6457041331935113 0.5184709833308756 1.0 1.0 5 P00374 1
Hur elavl1 binds and stabilizes mrna 0.5073475681338484 0.6417586869047125 0.5210298777021691 1.0 1.0 5 Q01105 1
Rac3 gtpase cycle 0.560725193826213 0.6275072659585036 0.5303267748364344 1.0 1.0 27 Q9Y2U8,Q14126,Q7L576,Q14739,Q9H0H5,P02786,Q9UQB8,Q9NSV4 8
Dap12 signaling 0.744571218255432 0.620530913272876 0.5349083082078565 1.0 1.0 2 P62993 1
Iron uptake and transport 0.5213624111374576 0.5999898758594876 0.5485129827460438 1.0 1.0 18 Q15904,P30519,P02786,Q9Y487,Q93050 5
Sphingolipid metabolism 0.543593096619589 0.5884781426834209 0.5562114006290089 1.0 1.0 25 P51648,Q16739,Q96G23,P10619,P17900,O15270,Q13510,Q06136,P07602,P16278,P06280 11
Hiv transcription initiation 0.477512700277697 0.5566782396798489 0.5777472869219242 1.0 1.0 9 Q92804,P19387,P18074 3
Insulin receptor recycling 0.4763585115688216 0.5376452672065896 0.5908219723235733 1.0 1.0 10 Q15904,Q93050 2
Runx1 interacts with co factors whose precise effect on runx1 targets is not known 0.479716464259679 0.5364691637277726 0.5916343419948706 1.0 1.0 11 P19784,P67870,Q969G3,Q8TAQ2,Q12824 5
Antigen presentation folding assembly and peptide loading of class i mhc 0.4859518446765852 0.5323568863632807 0.5944788396522243 1.0 1.0 13 Q9Y6B6,P10321,Q03518,Q9NZ08 4
Rhoj gtpase cycle 0.4919261271940439 0.5274000364562038 0.5979158182082625 1.0 1.0 15 Q01968,Q9NSV4,P02786,P14923,P42166 5
Diseases of glycosylation 0.4907201428252574 0.5227415761557973 0.6011541013748682 1.0 1.0 15 Q13724,O43505,P10619 3
Caspase mediated cleavage of cytoskeletal proteins 0.4738393515107055 0.5147198712985758 0.6067487854845899 1.0 1.0 5 P35611,Q13813,Q15149,P08670 4
Fgfr2 mutant receptor activation 0.4579646017699206 0.5087006112541996 0.6109620938876701 1.0 1.0 7 P30876,P13984,Q09161,P19387,P62875,P24928 6
Signaling by fgfr2 iiia tm 0.4579646017699206 0.5087006112541996 0.6109620938876701 1.0 1.0 7 P30876,P13984,Q09161,P19387,P62875,P24928 6
Adrenaline noradrenaline inhibits insulin secretion 0.5597315658492136 0.5018930425395537 0.6157427596004412 1.0 1.0 3 P04899 1
Wax and plasmalogen biosynthesis 0.5588556670218268 0.4991145852263801 0.6176986630764945 1.0 1.0 3 O00116 1
Signaling by fgfr2 in disease 0.4586599675121677 0.497170661677058 0.6190687084670856 1.0 1.0 8 P62875,P19387 2
Glycerophospholipid biosynthesis 0.5128274855781949 0.4847579562924172 0.6278480497008734 1.0 1.0 24 Q99943,Q9NPH0,P48651,Q8NCC3,P35790,Q96N66 6
Er quality control compartment erqc 0.6970923813029118 0.4739735455655842 0.6355187720810394 1.0 1.0 2 Q9UBV2 1
Phase i functionalization of compounds 0.4738190515530074 0.4719782065773685 0.636942344334009 1.0 1.0 14 P07099,Q16850 2
Gaba b receptor activation 0.4734982070368841 0.4537445372973919 0.6500127071027286 1.0 1.0 4 P04899 1
Gaba receptor activation 0.4734982070368841 0.4537445372973919 0.6500127071027286 1.0 1.0 4 P04899 1
Adp signalling through p2y purinoceptor 12 0.4734982070368841 0.4537445372973919 0.6500127071027286 1.0 1.0 4 P04899 1
G alpha z signalling events 0.4734982070368841 0.4537445372973919 0.6500127071027286 1.0 1.0 4 P04899 1
Dscam interactions 0.6834744203165302 0.4349114337988028 0.6636267149706099 1.0 1.0 2 P63000 1
Microrna mirna biogenesis 0.4380530973451423 0.4325083864932201 0.6653719582333817 1.0 1.0 7 P30876,P62487,P19387,P62875,P24928,Q9HAV4 6
Regulation of lipid metabolism by pparalpha 0.4625161419940682 0.42980802370717 0.6673352957315091 1.0 1.0 14 P11310,Q06520,Q71SY5 3
Rac2 gtpase cycle 0.5115417224269031 0.4288206754654938 0.6680537312913963 1.0 1.0 28 Q9Y2U8,Q14126,Q7L576,Q14739,Q9H0H5,P02786,Q86XL3,Q9NSV4 8
Signaling by flt3 fusion proteins 0.5340831361433211 0.4230055234365049 0.6722912311516089 1.0 1.0 3 Q14789 1
Met receptor recycling 0.4469417833456299 0.4184638945627214 0.675607979277784 1.0 1.0 5 P46108,P46109,P62993,P62330 4
Anti inflammatory response favouring leishmania parasite infection 0.4486258146783256 0.4182097176337539 0.6757937914615262 1.0 1.0 11 P10644 1
Rhoc gtpase cycle 0.4963534811487486 0.4117561104477354 0.6805181936382056 1.0 1.0 25 P41440,Q07021,Q14739,Q9H0H5,P02786,P14923,P49257,Q9NSV4 8
Regulation of cholesterol biosynthesis by srebp srebf 0.4780456698683036 0.4088867171794701 0.682622797232971 1.0 1.0 20 Q9UBM7 1
Linoleic acid la metabolism 0.6728008833272039 0.4053529248228643 0.6852181087518125 1.0 1.0 2 O95864 1
Post chaperonin tubulin folding pathway 0.4406464825120135 0.4021103740127079 0.6876027983430497 1.0 1.0 10 Q13885,P04350,Q9BUF5 3
Ra biosynthesis pathway 0.5261413843888085 0.3996954744630018 0.6893808257616427 1.0 1.0 3 Q8NBN7,Q9BTZ2 2
Cdc42 gtpase cycle 0.478243888903319 0.3846137732454656 0.7005235881279006 1.0 1.0 22 Q14739,Q9UQB8 2
Signaling by ctnnb1 phospho site mutants 0.4355474415868837 0.3796061437487512 0.7042377995746039 1.0 1.0 5 P48729 1
Beta catenin phosphorylation cascade 0.4355474415868837 0.3796061437487512 0.7042377995746039 1.0 1.0 5 P48729 1
Signaling by insulin receptor 0.4506253961542069 0.3739742829910104 0.7084234494390218 1.0 1.0 15 Q15904,Q06124,Q93050 3
Signaling by alk 0.4478821362799329 0.3719629734569707 0.7099204174295994 1.0 1.0 4 Q92769,P40763,Q13547 3
Stat3 nuclear events downstream of alk signaling 0.4478821362799329 0.3719629734569707 0.7099204174295994 1.0 1.0 4 Q92769,P40763,Q13547 3
Initiation of nuclear envelope ne reformation 0.4552548853689129 0.3654256187536762 0.7147937205731738 1.0 1.0 17 Q14739 1
Inla mediated entry of listeria monocytogenes into host cells 0.6551343393448706 0.3586152188639781 0.7198829601080621 1.0 1.0 2 P35222 1
Vitamin c ascorbate metabolism 0.6536621273463429 0.3548490457258199 0.7227026830361014 1.0 1.0 2 P78417 1
Runx1 regulates genes involved in megakaryocyte differentiation and platelet function 0.4258657834163643 0.3492198229138603 0.7269242853775135 1.0 1.0 10 Q03164,Q9HCE1 2
Maturation of sars cov 2 nucleoprotein 0.4397461081251005 0.3473490977821784 0.7283290694602687 1.0 1.0 4 P48729,Q99873 2
Metabolism of steroids 0.5215731535914195 0.3450469149972225 0.7300591009889161 1.0 1.0 38 Q9UBM7,Q14739,Q15392,Q16850 4
Rna polymerase iii transcription 0.4127444353756999 0.3407019183463852 0.733327994357742 1.0 1.0 7 P62875,Q9Y5Q8 2
Class i peroxisomal membrane protein import 0.4177696753850911 0.3333990705186342 0.7388330646848276 1.0 1.0 9 Q9NR77,P40855,P51648,Q8NBU5 4
Signaling by fgfr1 in disease 0.4090583617885523 0.3278775024935487 0.7430042846896399 1.0 1.0 7 O15164,P42224 2
Fgfr1 mutant receptor activation 0.4090583617885523 0.3278775024935487 0.7430042846896399 1.0 1.0 7 O15164,P42224 2
Incretin synthesis secretion and inactivation 0.4330996942016203 0.3277740075387353 0.7430825415618929 1.0 1.0 4 Q15005,P67812 2
Synthesis secretion and inactivation of glucagon like peptide 1 glp 1 0.4330996942016203 0.3277740075387353 0.7430825415618929 1.0 1.0 4 Q15005,P67812 2
Signaling by ptk6 0.426250353080948 0.3260133137912955 0.7444142820246642 1.0 1.0 12 Q07666,Q8IZL8,P11802,P46108,Q96JJ3,P23246,P18031,P63000 8
Rhog gtpase cycle 0.4882002652340966 0.324116883786579 0.7458495449102558 1.0 1.0 30 Q9Y2U8,Q14126,P34897,Q7L576,Q14739,P02786,Q86XL3,P49257,Q9NSV4 9
Signal amplification 0.4183708592529317 0.3235414176668828 0.7462852459549802 1.0 1.0 5 P04899,P63096 2
Other interleukin signaling 0.6374677953625376 0.3147907485194534 0.7529205365155374 1.0 1.0 2 P40222 1
G alpha s signalling events 0.4146902915362597 0.3119537131146652 0.7550757006880753 1.0 1.0 5 P04899 1
Potential therapeutics for sars 0.4922898023190015 0.3040400337126721 0.7610973914680867 1.0 1.0 33 Q99720 1
Regulation of tp53 activity through methylation 0.4213627992633567 0.2944390621676963 0.7684224217792082 1.0 1.0 4 O14744,P04637,O96017 3
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane 0.4211337211446907 0.2938046545664762 0.7689071781566814 1.0 1.0 4 P12236 1
Apc cdc20 mediated degradation of nek2a 0.3973214194238873 0.2880801875791626 0.7732853580729719 1.0 1.0 7 Q9H1A4 1
Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components 0.3973214194238873 0.2880801875791626 0.7732853580729719 1.0 1.0 7 Q9H1A4 1
Rhob gtpase cycle 0.4308589224374236 0.2829474291938332 0.7772171362399918 1.0 1.0 17 P41440,Q9NSV4,P02786 3
Keratan sulfate degradation 0.4162480767331884 0.280426676480596 0.7791501728864674 1.0 1.0 4 P15586,P16278 2
Signaling by egfr 0.399634100596231 0.2724840526291858 0.7852498516980093 1.0 1.0 9 Q9UBC2,Q92783,Q06124 3
Interleukin 15 signaling 0.6142804563857254 0.2620164387119642 0.7933087685580247 1.0 1.0 2 P62993 1
Cargo concentration in the er 0.4103586357481985 0.2618543484602668 0.7934337364525452 1.0 1.0 13 Q9Y6B6,Q12907,Q96PC5,P49257 4
Mtorc1 mediated signalling 0.3909996311324097 0.2560091699895434 0.7979437565947118 1.0 1.0 8 Q6IAA8,P62942,P62753,P06730,P23588,P31946,P42345 7
Regulation of pten localization 0.6109679793890379 0.2549365578675808 0.7987720998254804 1.0 1.0 2 P98170 1
Golgi associated vesicle biogenesis 0.4529246268606878 0.2544967464583517 0.7991118173197502 1.0 1.0 26 O75976,P11717,Q99523 3
Mtor signalling 0.3911439114391218 0.245350331513232 0.80618518347643 1.0 1.0 9 Q6IAA8,Q9Y376,P62942,P62753,P06730,P23588,P31946,P42345 8
Rhoq gtpase cycle 0.4094976877588853 0.2373273841872702 0.812402819355799 1.0 1.0 15 Q9HD26,P02786 2
Signaling by fgfr in disease 0.4053341096907384 0.2352035375866445 0.8140507604132532 1.0 1.0 14 P19387,P62875,O15164,P42224 4
Interleukin 4 and interleukin 13 signaling 0.3949019178070274 0.22458318325264 0.8223035485361203 1.0 1.0 12 P09601,P42224,Q07820 3
Signaling by fgfr2 0.4152083821802539 0.2231092789640273 0.823450456796073 1.0 1.0 18 P19387,P09651,P62875,P62993,Q06124 5
Signaling by fgfr 0.4152083821802539 0.2231092789640273 0.823450456796073 1.0 1.0 18 P19387,P09651,P62875,P62993,Q06124 5
Wnt mediated activation of dvl 0.4524977015469627 0.214254257297091 0.8303487870952391 1.0 1.0 3 P67870 1
Extracellular matrix organization 0.4251806005463086 0.2118692436451978 0.8322090458894773 1.0 1.0 22 O75718,Q32P28,P13674,Q02809,Q08722,P07384 6
Trans golgi network vesicle budding 0.4594439058195801 0.2030102612881276 0.8391270118664491 1.0 1.0 33 O75976,P11717,P02786,Q99523,P20645 5
Synthesis secretion and inactivation of glucose dependent insulinotropic polypeptide gip 0.4379670365600419 0.1851154120404416 0.8531385134610339 1.0 1.0 3 Q15005 1
Synthesis secretion and deacylation of ghrelin 0.4379670365600419 0.1851154120404416 0.8531385134610339 1.0 1.0 3 Q15005 1
Mismatch repair 0.3743210689358934 0.1844494624899436 0.853660869944133 1.0 1.0 10 Q9UQ84 1
Apc c cdc20 mediated degradation of cyclin b 0.3660323070495611 0.1806618529016067 0.8566330029834133 1.0 1.0 8 Q9H1A4 1
Pi5p regulates tp53 acetylation 0.4270986745213567 0.1650676289398074 0.868890751821112 1.0 1.0 3 P04637,Q8TBX8 2
Met activates ras signaling 0.3668508287292942 0.1628618965794087 0.8706271723349215 1.0 1.0 4 Q9NWH9,P62993,Q96S59 3
Non integrin membrane ecm interactions 0.3596168017686137 0.1596186078901729 0.8731815199475934 1.0 1.0 5 Q9Y296,O14936,P12814,P11047 4
Sars cov 2 infection 0.3916190112891523 0.1559132566513997 0.8761013958037944 1.0 1.0 18 Q10472,Q13724,P46977 3
Syndecan interactions 0.3594843462246929 0.1482825957748563 0.8821197500737423 1.0 1.0 4 Q9Y296,O14936,P12814 3
Rhoa gtpase cycle 0.4527981331116003 0.14779093813453 0.8825077611229657 1.0 1.0 37 P41440,Q15904,Q07021,P30519,Q14739,Q9H0H5,P02786,P14923,P28288,P49257,Q9NSV4 11
Signalling to erks 0.3566962493602379 0.1456033765575208 0.8842345022882847 1.0 1.0 9 P11233,P46108 2
Pre notch processing in golgi 0.3579416974891433 0.1453307394596421 0.8844497457808589 1.0 1.0 4 Q9UBV2,P16615 2
Rna polymerase iii transcription initiation from type 3 promoter 0.4112665684830652 0.1385719608760791 0.8897884014837536 1.0 1.0 3 P62875,O14802 2
Rna polymerase iii chain elongation 0.4112665684830652 0.1385719608760791 0.8897884014837536 1.0 1.0 3 P62875,O14802 2
Transcriptional regulation by e2f6 0.3408688116729083 0.1228052144435397 0.9022613449902166 1.0 1.0 7 P31350,P38398 2
Regulation of insulin secretion 0.3528385580770309 0.1181428572033795 0.905954466078336 1.0 1.0 11 P10644 1
Ros and rns production in phagocytes 0.3440094833577091 0.1134750010100332 0.9096539813546684 1.0 1.0 9 Q93050 1
Ephrin signaling 0.5241074714758999 0.1124908175429302 0.9104342500710982 1.0 1.0 2 P63000 1
Nef and signal transduction 0.5241074714758999 0.1124908175429302 0.9104342500710982 1.0 1.0 2 P63000 1
Ptk6 regulates rho gtpases ras gtpase and map kinases 0.3379760793966159 0.111989854635335 0.9108314507939808 1.0 1.0 5 P46108,Q96JJ3 2
Calnexin calreticulin cycle 0.3348082595870201 0.108010716862064 0.9139871911199466 1.0 1.0 7 P30101,P27797,P27824,Q14697,Q9NYU2,Q9UBV2 6
Assembly and cell surface presentation of nmda receptors 0.3399562088876818 0.1037707633825613 0.917351268619124 1.0 1.0 9 Q13885,Q14168,P04350,Q9BUF5 4
Synthesis of pa 0.3287546454063396 0.1018976840612476 0.918837888246926 1.0 1.0 6 Q9NPH0 1
Hdr through single strand annealing ssa 0.3457838092663445 0.1012013522000104 0.9193906233306848 1.0 1.0 11 P38398,Q9UQ84 2
Opioid signalling 0.3587052147882043 0.0991521173082444 0.9210174922921172 1.0 1.0 15 P10644 1
Ire1alpha activates chaperones 0.3750928774000324 0.0973532730450536 0.9224458511029618 1.0 1.0 20 O14773,O76024 2
Cd163 mediating an anti inflammatory response 0.5093853514906224 0.0965004712570138 0.9231230996652824 1.0 1.0 2 Q16539 1
Constitutive signaling by akt1 e17k in cancer 0.5079131394920946 0.0950230046652848 0.9242965545150212 1.0 1.0 2 P49840 1
Response to elevated platelet cytosolic ca2 0.3969353509652508 0.092717432235905 0.9261280477452768 1.0 1.0 27 O43852,P10909 2
Irak2 mediated activation of tak1 complex 0.5016562384983516 0.0889835844161299 0.9290949561005588 1.0 1.0 2 O43318 1
Traf6 mediated induction of tak1 complex within tlr4 complex 0.5016562384983516 0.0889835844161299 0.9290949561005588 1.0 1.0 2 O43318 1
Alpha protein kinase 1 signaling pathway 0.5016562384983516 0.0889835844161299 0.9290949561005588 1.0 1.0 2 O43318 1
Ticam1 traf6 dependent induction of tak1 complex 0.5016562384983516 0.0889835844161299 0.9290949561005588 1.0 1.0 2 O43318 1
Metabolism of vitamins and cofactors 0.4352349545342108 0.080470610777786 0.9358629696152309 1.0 1.0 40 Q07954,Q8N0U8,Q9H2D1,P00374,P43490 5
Rna polymerase i transcription termination 0.3184645324938526 0.0712610959080059 0.9431899574472522 1.0 1.0 7 P17480,P18074 2
Signaling by erythropoietin 0.4803091645196991 0.071177104254747 0.9432568033488944 1.0 1.0 2 P62993 1
Erythropoietin activates ras 0.4803091645196991 0.071177104254747 0.9432568033488944 1.0 1.0 2 P62993 1
G alpha i signalling events 0.3581456778887052 0.0673775927229751 0.9462811070617598 1.0 1.0 19 P07602,P10644 2
Gap junction trafficking and regulation 0.3337822086268956 0.0669730967351203 0.9466031207951038 1.0 1.0 12 P04350,Q9BUF5,Q07157,Q13885,Q96CW1 5
Rho gtpases activate iqgaps 0.3294162348931794 0.06511096003694 0.9480856541038768 1.0 1.0 11 P04350,Q9BUF5,P63000,Q13885,P35222 5
Nef mediated cd8 down regulation 0.3116833157482636 0.0642810548400965 0.948746438300028 1.0 1.0 5 P53680 1
Nef mediated cd4 down regulation 0.3116833157482636 0.0642810548400965 0.948746438300028 1.0 1.0 5 P53680 1
Synthesis of ip2 ip and ins in the cytosol 0.4692675745307408 0.0635550686904962 0.9493245093605134 1.0 1.0 2 Q01968 1
Fceri mediated ca 2 mobilization 0.4670592565329492 0.0621518418249038 0.9504419129558356 1.0 1.0 2 P62993 1
Antigen activates b cell receptor bcr leading to generation of second messengers 0.4670592565329492 0.0621518418249038 0.9504419129558356 1.0 1.0 2 P62993 1
Free fatty acids regulate insulin secretion 0.4630106735369978 0.0596801430968975 0.9524103870538134 1.0 1.0 2 O95573 1
Signaling by erbb2 in cancer 0.3354197349042731 0.0544214011795985 0.9565994284434164 1.0 1.0 3 Q16543,P62993 2
Constitutive signaling by overexpressed erbb2 0.3354197349042731 0.0544214011795985 0.9565994284434164 1.0 1.0 3 Q16543,P62993 2
Constitutive signaling by egfrviii 0.3354197349042731 0.0544214011795985 0.9565994284434164 1.0 1.0 3 Q16543,P62993 2
Constitutive signaling by ligand responsive egfr cancer variants 0.3354197349042731 0.0544214011795985 0.9565994284434164 1.0 1.0 3 Q16543,P62993 2
Signaling by erbb2 ecd mutants 0.3354197349042731 0.0544214011795985 0.9565994284434164 1.0 1.0 3 Q16543,P62993 2
Signaling by egfr in cancer 0.3354197349042731 0.0544214011795985 0.9565994284434164 1.0 1.0 3 Q16543,P62993 2
Diseases associated with glycosylation precursor biosynthesis 0.3097545545317994 0.0535911775736323 0.9572608856886164 1.0 1.0 7 P10619 1
Metabolism of water soluble vitamins and cofactors 0.3955231128894304 0.0528238571500816 0.9578722527776804 1.0 1.0 32 Q9H2D1,P00374,P43490 3
Tp53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain 0.3029810056515293 0.0509605066082284 0.9593569907953344 1.0 1.0 5 P04637,P06748,Q9UIV1 3
Met activates pi3k akt signaling 0.4464482885535605 0.0508539556758234 0.9594418960499452 1.0 1.0 2 P62993 1
Regulation of innate immune responses to cytosolic dna 0.2887234318372795 0.0486587476125655 0.9611912515448467 1.0 1.0 4 Q9UHD2 1
Tp53 regulates transcription of death receptors and ligands 0.4361428045638645 0.0463211982768513 0.9630542436605688 1.0 1.0 2 P04637 1
Tp53 regulates transcription of cell death genes 0.3173784977908712 0.0435399120887893 0.9652711494310888 1.0 1.0 3 P04637,P49327 2
Disassembly of the destruction complex and recruitment of axin to the membrane 0.3008520216186521 0.0433213261839963 0.965445391342697 1.0 1.0 6 P48729 1
Selective autophagy 0.3762303953313911 0.0415343068104758 0.9668699435619166 1.0 1.0 28 Q9BVA1,Q9NS69,P67870,P04350,Q9BUF5,Q8N4H5,P21796,O96008,O95140,P08670,P19784,Q15388,Q13885 13
Cd28 dependent vav1 pathway 0.2782010324336535 0.0397114171758133 0.9683231992680144 1.0 1.0 4 P62993 1
Interleukin 23 signaling 0.4136915715863177 0.0386350606253585 0.9691813488139474 1.0 1.0 2 P40763 1
Neurotransmitter clearance 0.4122193595877876 0.0382240337668921 0.969509058720796 1.0 1.0 2 P21964 1
Cytosolic sensors of pathogen associated dna 0.3325570630312179 0.0373011975816093 0.9702448506268176 1.0 1.0 16 Q9H2U1,P19474,P62875,P35222,Q9UHD2 5
Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects 0.4078027235922044 0.0370525198369496 0.9704431296894176 1.0 1.0 2 P11802 1
Rac1 gtpase cycle 0.3864511389558553 0.034918738716617 0.9721445383893824 1.0 1.0 32 Q14739,Q9UQB8 2
Rhod gtpase cycle 0.3573951235916316 0.0319340768268712 0.9745246231122392 1.0 1.0 24 Q9Y2U8,Q14739,Q9H0H5,Q5JTV8,P49257,Q9NSV4 6
Lysosome vesicle biogenesis 0.3144583159119506 0.0299026355665346 0.976144703912646 1.0 1.0 12 P20645 1
Caspase activation via extrinsic apoptotic signalling pathway 0.2816642120765854 0.0296038673420236 0.9763829809739152 1.0 1.0 3 Q9UKG1,P49327 2
Adp signalling through p2y purinoceptor 1 0.341553183658456 0.0276535901748397 0.9779384392078768 1.0 1.0 2 Q16539 1
Tp53 regulates transcription of genes involved in cytochrome c release 0.3172616856827472 0.0265516866345304 0.9788173081385448 1.0 1.0 2 P04637 1
Activated ntrk2 signals through cdk5 0.2881854987118238 0.0259414415807011 0.979304045556521 1.0 1.0 2 P63000 1
Mitochondrial protein import 0.3813393127926975 0.0192022748525368 0.984679742868313 1.0 1.0 33 Q9NS69,Q8N4H5,P21796,Q5JRX3,O60830,Q15388,Q99595,Q10713 8
Suppression of apoptosis 0.2434622467771693 0.0189106336701432 0.9849123966164556 1.0 1.0 4 P28482,P49840,P23246 3
Vitamin b5 pantothenate metabolism 0.24309392265194 0.0187527279320639 0.9850383648286276 1.0 1.0 4 Q9NRN7,P49327,Q9NVE7 3
Plasma lipoprotein assembly remodeling and clearance 0.3138557743940207 0.0169549440126277 0.9864725600686304 1.0 1.0 14 P53680,Q8WTV0,Q9Y6B6 3
Adherens junctions interactions 0.2854249822933247 0.0168962903614047 0.9865193522084644 1.0 1.0 6 P35222 1
Cell cell junction organization 0.2854249822933247 0.0168962903614047 0.9865193522084644 1.0 1.0 6 P35222 1
Sars cov infections 0.4406468450801074 0.0164844241091525 0.9868479281613658 1.0 1.0 51 Q99720,Q13724 2
Homologous dna pairing and strand exchange 0.3062230819194274 0.0160499836539066 0.9871945156301144 1.0 1.0 12 P38398,Q9UQ84 2
Fgfr2 alternative splicing 0.3089430894308995 0.0147260219980723 0.9882507590555878 1.0 1.0 13 P30876,P13984,Q09161,P62487,P19387,P09651,P52597,P62875,P26599,Q01085,P52272,P24928 12
Peptide hormone metabolism 0.3034968294171722 0.011718605647117 0.9906501194770276 1.0 1.0 12 Q8TAG9,Q15005,P67812 3
Cargo recognition for clathrin mediated endocytosis 0.3595566003227955 0.0113773898587754 0.9909223521325584 1.0 1.0 28 P53680,P02786,P11717,P20645 4
Sulfur amino acid metabolism 0.2944690236802717 0.0034524811914688 0.9972453240333172 1.0 1.0 11 Q9UBX3 1
Intraflagellar transport 0.2976540694362071 0.0028584142838197 0.9977193184802926 1.0 1.0 12 Q9BVA1,P04350,Q9BUF5,A0AVF1,Q13885,Q92973 6