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Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
Neutrophil degranulation 0.6479133665240449 5.774056956665462 7.738525903928382e-09 1.0864831389850485e-05 1.0864890370519448e-05 191 Q08722,O15126,P10321,P07858,P07602,P34059,P17900,Q9UJU6,P16278,O00584,Q13576,P11717,Q99536,O75629,P07384,P04066,Q16539,P06280,P08236,Q8N1F8,Q9BTY2,P68402,P01889,P15586,P53634,Q9UNP9,P10253,Q93050,O60784,Q92820,P10619,P13473,P11279,Q9NV96,Q96BM9,Q13510,P07686,P15291,P61916,P27105,O15260,P42785,P61160,P04439,O00462,Q99519,Q8WVQ1,P06756,O00754,O00560,Q92542 51
Innate immune system 0.550450802939479 5.2985479029276945 1.1672725510887721e-07 0.0001638716473137 8.194253308713379e-05 301 Q08722,P10321,P07858,P07602,P34059,Q9UQ16,P17900,P05067,Q04656,P16278,O00584,Q13576,P11717,Q99536,O75629,P07384,P04066,Q16539,P06280,Q99538,P28070,P08236,Q8N1F8,Q9BTY2,P68402,P01889,P15586,P53634,Q9UNP9,P10253,Q93050,O60784,Q8IV08,Q92820,P10619,P04114,P13473,P11279,Q9NV96,P49721,Q96BM9,P61421,Q13510,P07686,P15291,P61916,P27105,Q13685,O15260,P42785,P04439,O00462,Q99519,Q8WVQ1,O00754,O00560,Q9UQB8,P28074,P28072,Q92542 60
Vesicle mediated transport 0.4635839497686741 3.852997485988748 0.0001166805889374 0.1511129198660017 0.0546065156227198 273 O60645,Q99523,Q8TD16,Q9UQ16,Q9UIQ6,Q9NVZ3,Q8TAG9,P05067,Q13190,P98164,Q16706,O75976,O43752,Q9UNS2,P11717,Q9NSK0,P02786,Q07954,O15027,Q12907,Q9Y6B6,Q5KU26,O00461,Q9Y3E7,O43493,Q14108,Q8WTV0,P68402,Q10472,Q92783,P20645,P15586,P84085,Q14671,P53634,Q9Y6I3,P04114,P31751,P62258,O43731,O60333,Q9Y3P9,O15260,Q5JRA6,P61160,Q14203,P39880,Q9Y496,O95486,P31749,Q04917,O14657,Q9UBW8,P31946,Q9BT78,Q10471,Q9BRG1,Q9UN37,Q92572 59
Metabolism of carbohydrates 0.5560111255257895 3.780030869444118 0.0001568089160528 0.1976232204073922 0.0550399295345517 104 Q7LGA3,O00462,O60512,P34059,P06865,Q93063,O00754,P08236,P07686,Q11206,P16278,Q9NRB3,P54802,Q9P2E5,P15586,O43505,P10253,Q8NCH0 18
Membrane trafficking 0.4437462587093215 3.4931710846054056 0.0004773205966281 0.488454175283962 0.1139511760276355 265 O60645,Q99523,Q8TD16,Q9UQ16,Q9UIQ6,Q9NVZ3,Q8TAG9,P05067,Q13190,P98164,Q16706,O75976,O43752,Q9UNS2,Q9NSK0,P11717,P02786,O15027,Q12907,Q9Y6B6,O00461,Q9Y3E7,O43493,Q14108,P68402,Q10472,Q92783,P20645,P15586,P84085,Q14671,P53634,Q9Y6I3,P04114,P31751,P62258,O43731,O60333,Q9Y3P9,O15260,Q5JRA6,P61160,Q14203,P39880,Q9Y496,O95486,P31749,Q04917,O14657,Q9UBW8,P31946,Q9BT78,Q10471,Q9BRG1,Q9UN37,Q92572 56
Cs ds degradation 0.9772794334611968 2.880780499273083 0.0039669179765118 0.9962298071343496 0.1139511760276355 2 P06865 1
Diseases associated with o glycosylation of proteins 0.9737385659486574 2.866339157367737 0.0041524911005943 0.9970976537975614 0.1139511760276355 2 Q9UHI8 1
Trafficking and processing of endosomal tlr 0.9698037849785968 2.8471638816227824 0.0044110647948818 0.9979843920820264 0.1139511760276355 3 P07858 1
Hs gag biosynthesis 0.9687223369725568 2.8458374891950062 0.0044294794011292 0.9980360613947248 0.1139511760276355 2 Q7LGA3 1
Transport of small molecules 0.4427707354468925 2.844446237351931 0.0044488693015922 0.9980890373109202 0.1139511760276355 167 P08195,Q9UBX3,Q9C0H2,P30825,O15118,Q04656,Q9UBI6,P08183,P38571,Q9UNS2,P02786,Q9H2J7,Q9Y6B6,P28070,Q8WTV0,Q9BU23,P51797,Q8NB49,Q70HW3,Q15904,Q93050,P04114,P61421,P51790,Q13555,Q9Y487,P49721,P40855,P61916,Q8TAD4,P27105,Q9NQ11,Q9NWR8,P35670,P10644,P51798,P28074,P28072 38
Keratan sulfate degradation 0.9592439456585914 2.7983906015835416 0.0051357963731073 0.999274926831406 0.1139511760276355 5 P15586,P06865,P07686,P34059 4
Hs gag degradation 0.950413223140493 2.767135820349814 0.0056551189395441 0.9996516567489548 0.1139511760276355 3 P54802,P16278 2
Heparan sulfate heparin hs gag metabolism 0.9509746012994658 2.763881748937243 0.0057118234861841 0.9996784605963284 0.1139511760276355 5 Q7LGA3,P54802,Q93063,P16278 4
Mucopolysaccharidoses 0.9509746012994652 2.763881748937243 0.0057118234861841 0.9996784605963284 0.1139511760276355 5 P15586,P54802,P16278,P34059 4
Maturation of protein 3a 0.9477722041900234 2.759662934604749 0.0057861025944976 0.999710478599602 0.1139511760276355 2 Q11206 1
Vitamin d calciferol metabolism 0.9466450771355148 2.748447991579656 0.005987813351505 0.9997822494281624 0.1139511760276355 4 Q99538,P98164 2
Intrinsic pathway of fibrin clot formation 0.9448214812629055 2.7474539255838013 0.0060059946821775 0.9997877702000714 0.1139511760276355 2 P42785 1
Formation of fibrin clot clotting cascade 0.9448214812629055 2.7474539255838013 0.0060059946821775 0.9997877702000714 0.1139511760276355 2 P42785 1
Scavenging by class b receptors 0.942460902921216 2.737673893276657 0.0061875398181987 0.9998357783985352 0.1139511760276355 2 Q8WTV0 1
Akt phosphorylates targets in the nucleus 0.942165830628501 2.7364505867759807 0.0062105921497752 0.9998410405110264 0.1139511760276355 2 P31749 1
Chondroitin sulfate biosynthesis 0.94010032457952 2.727882443550851 0.0063742319736912 0.999873853461892 0.1139511760276355 2 Q9NRB3 1
Noncanonical activation of notch3 0.9395101799940956 2.7254327952996835 0.0064217248198124 0.9998820412588444 0.1139511760276355 2 Q92542 1
Chondroitin sulfate dermatan sulfate metabolism 0.9409332545776694 2.721788250638205 0.00649297317788 0.999893339374125 0.1139511760276355 5 Q9NRB3,P06865,Q8NCH0,P07686 4
N glycan antennae elongation 0.9391971664698912 2.7204944544188128 0.0065184365223269 0.9998971092822724 0.1139511760276355 3 Q11206,O60512 2
Keratan sulfate biosynthesis 0.9394744611750858 2.7184750084903393 0.0065583609992188 0.999902753931866 0.1139511760276355 4 O43505,Q11206,O60512 3
Keratan sulfate keratin metabolism 0.9408633944411526 2.716992314388968 0.0065878137454318 0.9999067187345166 0.1139511760276355 9 O60512,P34059,P06865,P07686,P16278,P15586,O43505,Q11206 8
Diseases associated with glycosaminoglycan metabolism 0.9397519196692228 2.7168223293876497 0.0065911979746076 0.9999071638312048 0.1139511760276355 5 P06865,Q93063,Q8NCH0,P07686 4
Endosomal vacuolar pathway 0.9350457632122842 2.699910037472384 0.0069358228210854 0.9999429636836948 0.1139511760276355 4 Q9UIQ6,P10321,P01889 3
Hyaluronan uptake and degradation 0.9300532253025556 2.678932668575002 0.0073857243721615 0.9999698112120832 0.1139511760276355 4 P06865,P07686 2
Hyaluronan metabolism 0.9300532253025556 2.678932668575002 0.0073857243721615 0.9999698112120832 0.1139511760276355 4 P06865,P07686 2
O linked glycosylation of mucins 0.9291199054932044 2.671998295216048 0.0075401031505588 0.9999757335908052 0.1143005463725866 5 Q86SF2,Q10472,Q11206,O43505 4
O linked glycosylation 0.9293943870014774 2.670617355220928 0.0075711900375003 0.999976777659154 0.1143005463725866 6 Q86SF2,Q10472,Q9UHI8,O43505,Q11206 5
Tryptophan catabolism 0.9247565653585084 2.663958662264698 0.0077227052108272 0.9999812583516988 0.1153476395319311 2 P08195 1
Glycosaminoglycan metabolism 0.921021810683605 2.6526891394071725 0.0079853375326641 0.9999870759041708 0.1161942855304183 19 Q7LGA3,O60512,P34059,P06865,P08236,Q9P2E5,Q93063,P16278,P07686,Q9NRB3,P54802,P15586,O43505,Q11206,Q8NCH0 15
Reactions specific to the complex n glycan synthesis pathway 0.9203304809678284 2.6454287673210097 0.0081587462875905 0.9999898887738105 0.1161942855304183 2 P04066 1
Synthesis of pyrophosphates in the cytosol 0.9197403363824082 2.642955047759358 0.0082185945826931 0.99999071012076 0.1161942855304183 2 Q13572 1
N glycan antennae elongation in the medial trans golgi 0.9211458948611884 2.638225302193249 0.0083341190871157 0.9999921117402129 0.1161942855304183 5 P15291,P04066,O60512,Q11206 4
Runx2 regulates genes involved in cell migration 0.9159016844966762 2.6227911111283957 0.0087212725715273 0.9999954408470976 0.1200457518669055 3 P31749 1
Sialic acid metabolism 0.8982445354813967 2.535376273501989 0.0112326600398264 0.999999870540379 0.1388079539024334 7 Q99519,Q11206,P10619 3
Elastic fibre formation 0.8863971673059909 2.502011249769754 0.0123490000819663 0.999999973495178 0.1388079539024334 2 P06756 1
Molecules associated with elastic fibres 0.8863971673059909 2.502011249769754 0.0123490000819663 0.999999973495178 0.1388079539024334 2 P06756 1
Adaptive immune system 0.4057525558841359 2.5015654902203215 0.0123645571620614 0.9999999740749088 0.1388079539024334 197 P10321,P07858,P05556,O15111,Q9UQ16,Q9UIQ6,P63104,Q9C0C9,Q9H1A4,Q99436,Q9ULT8,Q9NZ08,Q9NSK0,Q9BUF5,O95239,P30154,Q9Y6B6,P52888,Q5KU26,P28070,Q99538,Q9UJX4,Q9UBG0,P01889,P55786,P78310,P53634,O94822,P10619,P31751,Q9Y297,P49721,P62942,Q15386,P49720,P20618,P60604,P04439,Q14203,Q6P179,Q9Y496,Q13867,Q9UJX5,P06756,P46934,O95486,P31749,Q9GZZ9,P31946,Q13616,Q6UWE0,P28074,P28072 53
Regulation of tp53 activity through association with co factors 0.887301587551241 2.501291321104145 0.0123741343283891 0.9999999744254804 0.1388079539024334 3 P31749 1
Ecm proteoglycans 0.8744661444705946 2.4418422503646577 0.0146125302002229 0.9999999989425062 0.1467506998488811 4 P06756,P05067 2
Downregulation of erbb2 erbb3 signaling 0.8732072955430941 2.440782805241107 0.0146554660025866 0.9999999990052616 0.1467506998488811 3 P31749 1
Tetrahydrobiopterin bh4 synthesis recycling salvage and regulation 0.8719519177861945 2.4309644324190516 0.0150586927317668 0.99999999944007 0.1467506998488811 4 P00374,P31749 2
Formyl peptide receptors bind formyl peptides and many other ligands 0.8706513253706726 2.429764808943375 0.0151086234227328 0.9999999994785386 0.1467506998488811 3 P05067 1
Class a 1 rhodopsin like receptors 0.8727633942438732 2.422343144657087 0.0154207814382112 0.999999999665856 0.1467506998488811 8 P04083,P05067,P07602,P42892 4
Peptide ligand binding receptors 0.8727633942438732 2.422343144657087 0.0154207814382112 0.999999999665856 0.1467506998488811 8 P04083,P05067,P07602,P42892 4
Amino acid transport across the plasma membrane 0.8689059404752806 2.4177680463462052 0.0156160277319898 0.9999999997470668 0.147146999568549 4 Q9H2J7,P08195 2
Diseases of carbohydrate metabolism 0.8681993073220184 2.398694554081275 0.0164536332194606 0.9999999999234486 0.1528082373194552 11 P34059,P16278,P54802,P15586,P10253 5
Cd28 dependent pi3k akt signaling 0.8638038281012221 2.3956196042475537 0.0165922999388856 0.9999999999371968 0.1528082373194552 4 P31749 1
Binding and uptake of ligands by scavenger receptors 0.8667830525606028 2.3942987361834507 0.0166521797078893 0.999999999942343 0.1528082373194552 9 Q07954,Q5KU26,Q8WTV0 3
Laminin interactions 0.8584590224028645 2.3723584367158175 0.0176749347884102 0.9999999999866236 0.1560812142545447 4 P06756,P23229 2
Glycosphingolipid metabolism 0.8578996806971428 2.3571864113881738 0.018414000586997 0.9999999999953504 0.1576418099033162 17 Q99519,P10619,P07602,P06280,P06865,P04062,P17900,Q13510,P07686,P16278 10
Integrin cell surface interactions 0.8552686396398486 2.350147722278547 0.0187659617769666 0.9999999999971898 0.1587193393666336 6 Q08722,P23229,P06756,Q9Y624 4
Stimuli sensing channels 0.8520676080629693 2.330751016368519 0.0197664923846134 0.9999999999993292 0.1630292691129015 8 Q9C0H2,P51797,P27105,P51790 4
Gpcr ligand binding 0.8475082139266974 2.3056832903833557 0.0211283354599232 0.9999999999999049 0.1704838102628286 11 P04083,P07602,P05067,P42892,Q9UBI6 5
Amyloid fiber formation 0.843294219696858 2.2942366185054475 0.0217769109940044 0.9999999999999624 0.1717684440201251 7 Q08431,P05067,Q9Y287 3
Tgf beta receptor signaling in emt epithelial to mesenchymal transition 0.8355962219598494 2.2772607822765347 0.0227706573770158 0.999999999999991 0.1776111275407239 3 Q9Y624,P62942 2
Tak1 activates nfkb by phosphorylation and activation of ikks complex 0.8337000125346437 2.259037210833548 0.0238810703012484 0.9999999999999982 0.1832187032948239 5 P05067 1
Akt phosphorylates targets in the cytosol 0.8329354013167145 2.2556500758188185 0.024092554473033 0.9999999999999988 0.183836665652926 5 P31751,P31749 2
Traf6 mediated nf kb activation 0.8274434325101817 2.2312850141517453 0.0256622556988241 1.0 0.1906581443232753 5 P05067 1
Receptor type tyrosine protein phosphatases 0.822661552080264 2.2261008222968512 0.0260074288830352 1.0 0.1921364948307983 2 P10586 1
Tight junction interactions 0.8208911183239727 2.2183148612874626 0.0265333715817845 1.0 0.1931840034107745 2 Q9Y624 1
Scavenging by class a receptors 0.8233334745667524 2.2179840392282144 0.0265559206967802 1.0 0.1931840034107745 4 Q5KU26 1
Zinc efflux and compartmentalization by the slc30 family 0.8191206845677113 2.2105223591058833 0.0270689305088538 1.0 0.1946337173984536 2 Q8TAD4 1
Assembly of collagen fibrils and other multimeric structures 0.8213188621020009 2.209051072267244 0.0271710887536302 1.0 0.1946337173984536 4 P07858 1
P38mapk events 0.8167060212514685 2.1940076011753624 0.0282348631036941 1.0 0.2012271461806426 3 P11234,Q16539 2
Chylomicron assembly 0.8145797550601677 2.1845899334543346 0.0289189266840841 1.0 0.2040310204243926 3 Q9Y6B6 1
Notch4 activation and transmission of signal to the nucleus 0.80879315432279 2.1649360681758982 0.0303925815857648 1.0 0.2107755873391182 2 Q92542 1
Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps 0.8157027952490453 2.1638561964765923 0.0304753876280918 1.0 0.2107755873391182 19 P04114,O43493,P19022,P05067,Q9BTY2,O43852,Q06481,Q5JRA6,Q08431 9
G beta gamma signalling through pi3kgamma 0.8036732965702251 2.1250981069117785 0.0335784275161332 1.0 0.2223778878898637 5 Q9UBI6,P31749 2
Metabolism of fat soluble vitamins 0.8022105136558414 2.1097377585079164 0.0348809502534022 1.0 0.224646119980627 7 P98164,Q07954 2
Enos activation 0.795733232360671 2.0948657213841195 0.0361829308036107 1.0 0.23071717740537 4 P31749 1
Constitutive signaling by akt1 e17k in cancer 0.7921987897670312 2.0682820568568157 0.0386135080167113 1.0 0.2409482900242789 6 P31751,P31749 2
Molybdenum cofactor biosynthesis 0.7831030195596879 2.0380011360983374 0.0415498192539618 1.0 0.2555905530324887 4 Q9Y697 1
Formation of the cornified envelope 0.7852280386920589 2.0366193443394396 0.041688202738205 1.0 0.2555905530324887 6 Q14126,Q14574 2
Keratinization 0.7852280386920589 2.0366193443394396 0.041688202738205 1.0 0.2555905530324887 6 Q14126,Q14574 2
Hemostasis 0.396710311585376 2.0309925359274827 0.0422557517753359 1.0 0.2579438064894418 137 Q08722,P05556,P07602,P08195,P54709,Q96N67,Q9UNF1,P05067,Q96ST3,Q06481,Q9UBI6,Q92520,P23634,Q9NSK0,Q9Y624,Q9BUF5,P30154,Q16539,P61586,P78310,Q08380,Q92896,Q07021,P23229,P04114,P13473,O60333,Q13685,P42785,Q9Y496,Q9H4M9,P06756,P10644,P31749,O43852,Q13572,P29992 37
Arms mediated activation 0.7751549129536599 2.0149342816873728 0.0439115354169483 1.0 0.2623480669165766 2 P31946 1
Degradation of the extracellular matrix 0.781708910048294 2.006234522004876 0.0448312322670434 1.0 0.2667078394191906 10 P07858,Q92542,P17655,Q9UHI8 4
Translation of sars cov 1 structural proteins 0.7782835341811376 2.000660686562443 0.0454289688034932 1.0 0.2679927403365735 7 Q11206 1
Myogenesis 0.7725807727979718 1.9744912599819353 0.0483259102707116 1.0 0.2771661442591287 7 Q92859,Q16539 2
Transport of inorganic cations anions and amino acids oligopeptides 0.7749886332485512 1.9724058130401836 0.0485632987804456 1.0 0.2771661442591287 11 Q9H2J7,P08195,P30825,Q9UBX3 4
Plasma lipoprotein remodeling 0.7562903909069985 1.9228109157937467 0.0545038007100193 1.0 0.3040826340318315 3 P04114 1
Wnt mediated activation of dvl 0.7524343464148613 1.9123345989601104 0.0558332907228831 1.0 0.3080941147254649 2 P19784 1
Notch3 activation and transmission of signal to the nucleus 0.7532989982714189 1.9091940976623931 0.0562370574303934 1.0 0.3080941147254649 3 Q92542 1
Plasma lipoprotein assembly 0.7545783372599134 1.908398883040542 0.0563396811138523 1.0 0.3080941147254649 4 Q9Y6B6 1
G protein beta gamma signalling 0.7569794001452193 1.9073074381624555 0.0564807875696029 1.0 0.3080941147254649 6 Q9UBI6,P31749 2
Receptor mediated mitophagy 0.7526564344746081 1.906266909281714 0.0566155851845939 1.0 0.3080941147254649 3 P19784,Q96HS1 2
Interleukin 37 signaling 0.7465680628171234 1.8784924595045045 0.0603138276430796 1.0 0.3196110055411719 3 P40763 1
Estrogen dependent nuclear events downstream of esr membrane signaling 0.7492270854137406 1.877517757525488 0.0604471658640846 1.0 0.3196110055411719 5 P31749 1
Ticam1 rip1 mediated ikk complex recruitment 0.7438772499262147 1.8734347978129449 0.061008368579084 1.0 0.3196110055411719 2 O15111 1
Irak1 recruits ikk complex 0.7438772499262147 1.8734347978129449 0.061008368579084 1.0 0.3196110055411719 2 O15111 1
Dna damage reversal 0.7458686773606057 1.868511106692934 0.0616908634657729 1.0 0.3219850271596474 4 Q9H1I8,Q9C0B1 2
Plasma lipoprotein clearance 0.7511051974638112 1.8522637875079688 0.0639879530212828 1.0 0.3327373557106705 15 P61916,O15118,Q8WTV0,P38571 4
Cd163 mediating an anti inflammatory response 0.7385659486573996 1.849220980572866 0.0644259104010722 1.0 0.3332527488592297 2 Q16539 1
Immunoregulatory interactions between a lymphoid and a non lymphoid cell 0.7450528543936407 1.8472687822392424 0.0647081950139045 1.0 0.3332527488592297 7 P10321,Q5KU26,P01889,P78310,P04439 5
Glutamate neurotransmitter release cycle 0.7396047695717682 1.846641291292923 0.0647991456115169 1.0 0.3332527488592297 3 O75915 1
Phosphorylation of emi1 0.7377716049470486 1.8382411653266095 0.0660268763648714 1.0 0.3370972160591983 3 P53350 1
Transferrin endocytosis and recycling 0.7436754487962625 1.8251436740628149 0.0679793510273878 1.0 0.3415750493747521 11 Q15904,Q93050,P61421,P02786 4
Activated tak1 mediates p38 mapk activation 0.7309243790029522 1.8068108228124704 0.0707917806429057 1.0 0.3524526951157432 3 Q16539 1
Erbb2 regulates cell motility 0.7276482738270849 1.7992857532182267 0.0719734905376494 1.0 0.3536134618242315 2 P61586 1
Intra golgi and retrograde golgi to er traffic 0.3948259129159089 1.789346507311095 0.0735590284856475 1.0 0.3566093995100166 103 Q8TD16,Q15102,Q13190,Q16706,O43752,Q9NSK0,P11717,P24390,Q9BUF5,O95239,O00461,O43493,Q9Y2V7,Q9P2W9,Q9NP72,P68402,Q10472,Q9H9E3,P20645,Q9H2M9,P84085,Q96MW5,P35606,Q8TBA6,P49755,O43731,Q13885,Q15042,O60333,O15260,O14579,Q14203,P39880,Q9Y496,P43034,Q9UBF2,Q9Y678,Q99747,Q10471,P04350,O00139,P18085 42
Activation of bad and translocation to mitochondria 0.7332125955426118 1.7873172519040563 0.0738862272338336 1.0 0.3566093995100166 8 P31751,P62258,P31749,Q04917,P31946 5
Class i mhc mediated antigen processing presentation 0.3803825745525457 1.7814959874370386 0.0748314598185138 1.0 0.3573583999496373 121 P10321,O15111,Q9UIQ6,Q9C0C9,Q9H1A4,Q99436,Q9ULT8,Q9NZ08,Q9Y6B6,P52888,P28070,Q9UJX4,Q9UBG0,P01889,P55786,O94822,Q9Y297,P49721,Q15386,P49720,P20618,P60604,P04439,Q6P179,Q13867,Q9UJX5,P06756,P46934,O95486,Q9GZZ9,Q13616,Q6UWE0,P28074,P28072 34
Flt3 signaling 0.7245078994726842 1.7632260863896003 0.0778623657395827 1.0 0.3647317485555344 5 P31749 1
Ldl clearance 0.7305914538746794 1.7572640316304076 0.0788728155629581 1.0 0.3652605670941199 13 P61916,O15118,P38571 3
Trans golgi network vesicle budding 0.7089556766092057 1.756127120846814 0.0790667051988609 1.0 0.3652605670941199 40 Q99523,O43493,P05067,Q92572,O75976,P20645,P15586,P11717,P02786 9
Signalling to ras 0.7197128432730935 1.7478848641147502 0.0804839662732441 1.0 0.3697776415077517 4 P11234,Q16539 2
Interferon alpha beta signaling 0.7264469437716212 1.7469698107547151 0.0806425749394712 1.0 0.3697776415077517 10 P10321,P01889 2
Synaptic adhesion like molecules 0.7202979656500332 1.7316520691252957 0.0833355294271869 1.0 0.3739568813582538 7 P41440,P10586,O75955,Q15334 4
Transport and synthesis of paps 0.7128946591914884 1.7314705097157277 0.0833678802458215 1.0 0.3739568813582538 2 O43252 1
Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux 0.7146643129879167 1.724463294980361 0.0846242396753753 1.0 0.3772819031496072 4 Q9BZK7 1
Regulation of localization of foxo transcription factors 0.715559863037692 1.7149621223839318 0.0863521716996342 1.0 0.3810645544809522 6 P31751,P31749 2
Regulation of gene expression in beta cells 0.7104295336690983 1.7122406984530072 0.0868523201096187 1.0 0.3810645544809522 3 P31749 1
Epha mediated growth cone collapse 0.7161294157452331 1.70694365006029 0.0878325265779516 1.0 0.3841646956867415 8 P35580,Q15375,P60660,Q13464,P61586,O75116 6
Stat3 nuclear events downstream of alk signaling 0.706949719722281 1.6885911119595716 0.091297815130299 1.0 0.3941937079493075 4 P40763 1
Netrin 1 signaling 0.71214963279472 1.68814814779048 0.0913827939073281 1.0 0.3941937079493075 8 Q92859,O94813 2
Plasma lipoprotein assembly remodeling and clearance 0.715925002943202 1.678143391040417 0.0933191097285184 1.0 0.3970303941176966 19 Q9Y6B6,P04114,O15118,Q8WTV0,P61916,P38571 6
Gap junction assembly 0.7031081376825343 1.6706921506655874 0.0947825000709428 1.0 0.3996235138126237 4 Q13885,Q9BUF5 2
Transport of connexons to the plasma membrane 0.7031081376825343 1.6706921506655874 0.0947825000709428 1.0 0.3996235138126237 4 Q13885,Q9BUF5 2
Diseases of glycosylation 0.7117826912754084 1.6582505998927846 0.0972668954614117 1.0 0.4088704228377907 21 Q99519,P10619,P06865,Q93063,P07686,P16278,Q9UHI8,O43505,Q8NCH0 9
Sphingolipid metabolism 0.7062454728758538 1.6475419675630534 0.0994466974394527 1.0 0.411658632923997 28 Q99519,P10619,P07602,P06280,P06865,P17900,P04062,Q13510,P16278,P07686 10
Glucagon signaling in metabolic regulation 0.7010666412276905 1.6469570299202154 0.0995668783823209 1.0 0.411658632923997 6 Q9UBI6 1
Vasopressin regulates renal water homeostasis via aquaporins 0.7010666412276905 1.6469570299202154 0.0995668783823209 1.0 0.411658632923997 6 Q9UBI6 1
Pre notch processing in golgi 0.6976363289742171 1.6377830947337402 0.1014669493178379 1.0 0.4120553824962246 5 Q11206 1
Dcc mediated attractive signaling 0.6925346709943982 1.6372925467202255 0.1015693575158542 1.0 0.4120553824962246 2 P60953 1
Nef and signal transduction 0.6925346709943947 1.6372925467202086 0.1015693575158578 1.0 0.4120553824962246 2 Q13177 1
Sema3a plexin repulsion signaling by inhibiting integrin adhesion 0.6925346709943927 1.6372925467202002 0.1015693575158596 1.0 0.4120553824962246 2 Q9Y490 1
Mitochondrial iron sulfur cluster biogenesis 0.6936894953044991 1.6344809996513296 0.1021578926353596 1.0 0.4120553824962246 3 Q9Y697 1
Sema4d induced cell migration and growth cone collapse 0.6996626487502806 1.6344756508863685 0.1021590148618338 1.0 0.4120553824962246 7 P35580,P60660,Q13464,P61586,O75116 5
Adp signalling through p2y purinoceptor 1 0.6943011889664532 1.622134095382368 0.1047746391746136 1.0 0.4202959811461643 5 Q9UBI6,Q16539 2
Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways 0.7007171798664944 1.6201850444443615 0.1051925330710925 1.0 0.4207701322843702 11 Q13685,P05067,Q16539 3
Ion channel transport 0.6963858000723878 1.6163185366615456 0.1060254610877056 1.0 0.4228970095657348 32 Q13555,P61421,P51790,Q9NQ11,Q9C0H2,P54709,Q9Y487,Q04656,P35670,P51798,P51797,P27105,Q8NB49,Q15904,Q93050 15
Golgi associated vesicle biogenesis 0.69266398012915 1.590542029562035 0.1117126796544967 1.0 0.4356393977717636 31 P11717,Q99523,O75976,P02786 4
Diseases of mismatch repair mmr 0.6794569067296322 1.5680381170984052 0.1168722369890513 1.0 0.44603750089586 3 P52701,P20585 2
Sumo is transferred from e1 to e2 ube2i ubc9 0.674535261138981 1.5535157763101364 0.1202999632207535 1.0 0.452818092123158 2 Q9UBE0 1
Sumo is conjugated to e1 uba2 sae1 0.674535261138981 1.5535157763101364 0.1202999632207535 1.0 0.452818092123158 2 Q9UBE0 1
Thromboxane signalling through tp receptor 0.6747895599999755 1.5228613213655424 0.12779340436245 1.0 0.4712491561050341 6 Q9UBI6,Q13685 2
Activation of rac1 downstream of nmdars 0.6662732369430522 1.5149162969046115 0.1297936027241741 1.0 0.47579691442491 2 P63000 1
Metabolism of nitric oxide nos3 activation and regulation 0.6723635035064799 1.5113578416724556 0.1306973043433681 1.0 0.4778620190054397 6 P31749 1
Cd28 co stimulation 0.6745907904971806 1.5095848998669126 0.1311493767764542 1.0 0.4782694155691993 8 P31749 1
Rora activates gene expression 0.6666910864873998 1.4999444986327142 0.1336287799434687 1.0 0.4860487229031869 4 Q86X55 1
Glucagon like peptide 1 glp1 regulates insulin secretion 0.6691722416739494 1.4897421465988578 0.1362920481222107 1.0 0.486152396973723 7 Q9UBI6 1
Cargo recognition for clathrin mediated endocytosis 0.6659800776849167 1.486066842365617 0.1372614416345836 1.0 0.486152396973723 37 Q9Y6I3,P04114,O43493,Q9NVZ3,Q14108,P98164,O14657,Q9UBW8,P20645,Q9UNS2,P11717,P02786 12
Rhob gtpase cycle 0.6768571215091826 1.4826828471808131 0.1381586940117631 1.0 0.486152396973723 23 P41440,Q8TAA9,Q9UDY2,Q14254,O75955,Q13464,P43121,P14923,P27105,P02786 10
Activation of bh3 only proteins 0.6725523170368871 1.479887657261467 0.1389032301340913 1.0 0.4866826158683123 12 P31751,P62258,P31749,Q04917,P31946 5
Dap12 interactions 0.6635460293158657 1.469490946139038 0.1416996757492175 1.0 0.4924414474056964 6 P10321 1
Rho gtpases activate ktn1 0.6653459042900293 1.4653473897728742 0.1428261632778156 1.0 0.4927075994385669 8 P60953,P61586,P63000,P84095,Q9NSK0,P33176 6
Regulation of tnfr1 signaling 0.6609698834320702 1.464908267744638 0.1429459468108418 1.0 0.4927075994385669 5 Q8TCT8 1
Insulin receptor recycling 0.6668430985613036 1.4614869699431408 0.1438818488388977 1.0 0.4927075994385669 10 Q15904,P61421,Q93050 3
Cell surface interactions at the vascular wall 0.6687021965771153 1.443365868902318 0.1489174334993863 1.0 0.5073007976820001 18 Q08722,P23229,P04114,P08195,P06756,P78310,Q92896,Q9Y624 8
Rho gtpase cycle 0.3525110733577865 1.4392576649225193 0.1500775327303447 1.0 0.5073007976820001 159 Q96AC1,P05556,Q14254,Q7L576,Q96N67,Q13190,P51648,Q14739,O75976,Q9P2R3,Q13576,P02786,Q96HY6,P67936,Q13464,P61586,Q8NBN3,P12814,Q92783,Q14126,Q15904,Q07021,Q5T0N5,Q8TAA9,P60953,Q9BX68,Q8IYB3,P43121,Q6IAA8,Q5VTR2,Q68EM7,P15924,P27105,P41440,Q9Y512,Q9UDY2,O75489,P52565,O75955,Q9P0I2,P14923,Q9BT78,Q9UQB8,Q96RT1,O15173 45
Gpvi mediated activation cascade 0.6570162481536208 1.4384326033341328 0.1503113474613333 1.0 0.5073007976820001 6 P60953,P61586,P63000,P84095,Q06124 5
Runx1 regulates transcription of genes involved in bcr signaling 0.649454116258486 1.436097214818868 0.1509746805260288 1.0 0.5079254325835293 2 Q13951 1
Striated muscle contraction 0.6555712309835555 1.4315538261829646 0.1522715520875632 1.0 0.5090220455498543 6 P09493 1
Tnf signaling 0.6557997335196313 1.4259105263650818 0.1538941705542325 1.0 0.511183066675435 7 Q8TCT8 1
Ephrin signaling 0.6496303966232027 1.419391625855842 0.1557848724742703 1.0 0.511183066675435 4 O00560,Q13177 2
Signal amplification 0.6566172620983025 1.4175733959838637 0.156315351902303 1.0 0.511183066675435 9 Q13685,Q9UBI6,Q16539 3
Lysosome vesicle biogenesis 0.6609371464866852 1.4119482689994791 0.1579651936685555 1.0 0.5133868794228055 15 P05067,P15586 2
Ras activation upon ca2 influx through nmda receptor 0.648967106026038 1.4079795814167233 0.1591371162320984 1.0 0.5136287613560143 5 Q13555,Q14168 2
Long term potentiation 0.648967106026038 1.4079795814167233 0.1591371162320984 1.0 0.5136287613560143 5 Q13555,Q14168 2
Unblocking of nmda receptors glutamate binding and activation 0.648967106026038 1.4079795814167233 0.1591371162320984 1.0 0.5136287613560143 5 Q13555,Q14168 2
Bmal1 clock npas2 activates circadian gene expression 0.6470877996424614 1.3990543654248344 0.1617966808907649 1.0 0.5210149999326467 5 Q86X55 1
Vegfr2 mediated vascular permeability 0.6528810825553563 1.3939642494072817 0.163328400717498 1.0 0.52390121433188 10 P31749 1
Metabolism of lipids 0.3388240258759039 1.3881823861586764 0.1650815144002 1.0 0.5259693752311373 198 P07602,P17900,P04062,Q15392,P16278,P98164,Q9UMR5,Q9Y6B6,P06280,Q99538,Q93074,P06865,Q8TBX8,Q9HBU6,P50897,Q8IV08,P10619,Q13510,P07686,Q86X55,P48449,Q8NCC3,Q99519,Q9BV79 24
Aquaporin mediated transport 0.6466211448628896 1.3820007334188225 0.1669714759117468 1.0 0.5279908832884969 7 Q9UBI6 1
Activation of nima kinases nek9 nek6 nek7 0.6423791934179209 1.3766799651287964 0.1686112156299373 1.0 0.5307850823866187 5 P53350,P06493 2
G protein activation 0.6396368290210946 1.3720824781300502 0.1700377634427003 1.0 0.5309107964518986 4 Q9UBI6 1
Ptk6 regulates rho gtpases ras gtpase and map kinases 0.6367706719597714 1.367300351229925 0.1715311816660176 1.0 0.5316330663556044 3 P61586 1
Rap1 signalling 0.6352504871563189 1.360120826176996 0.1737916916425268 1.0 0.5338090467092285 3 P31946 1
Nod1 2 signaling pathway 0.6415409839336094 1.3576695096246527 0.1745685758764359 1.0 0.5339744673867451 7 Q13685,Q16539 2
Attachment of gpi anchor to upar 0.6378820000369549 1.3552952564157466 0.1753235057374456 1.0 0.53511783055516 5 Q9H490 1
Repression of wnt target genes 0.6301652892561814 1.3360940820193077 0.1815185240808292 1.0 0.5470745942190395 3 Q13547,P56545 2
Telomere c strand synthesis initiation 0.631183139153532 1.332008123363219 0.182857519164884 1.0 0.5481273695117324 4 P49643 1
Syndecan interactions 0.6345455734802945 1.3312720018370825 0.1830995272799163 1.0 0.5481273695117324 6 P06756,P23229,P05556 3
Response to elevated platelet cytosolic ca2 0.6396177721730163 1.3195055479158295 0.1870001566018497 1.0 0.5552083695134581 34 P07602,P13473,P05067,O43852,Q06481,Q08380 6
Defective intrinsic pathway for apoptosis 0.642917595591733 1.319366264706256 0.1870466942876536 1.0 0.5552083695134581 16 Q07021,P05067,P07384,P17655 4
Extracellular matrix organization 0.6386390029521813 1.3043196110756123 0.1921246314949085 1.0 0.5654989153435044 32 Q08722,P13674,P05556,P07858,P23229,P06756,P05067,O15460,Q92542,P17655,Q9UHI8,Q9Y624,P07384 13
Signaling by erbb4 0.6283063515766223 1.2942111655807864 0.1955924910623543 1.0 0.5721080363573864 7 P46934,Q92542 2
Downregulation of erbb2 signaling 0.6245538395141939 1.2692666902786118 0.2043459623503274 1.0 0.5855137370201219 8 P31749 1
Non integrin membrane ecm interactions 0.6192889268093871 1.2509347534472357 0.2109582830715608 1.0 0.5944044076973084 7 P06756,P23229,P05556 3
Signaling by receptor tyrosine kinases 0.341247250102585 1.239790111300732 0.2150530367425684 1.0 0.5944044076973084 119 P05556,Q9UQ16,Q7L576,Q96N67,Q96ST3,P08069,P30154,Q16539,Q92783,Q15904,Q9Y6I3,Q93050,P31751,P61421,Q9Y487,Q96S59,Q13685,P06756,P46934,P13984,P11234,P31749,P31946,Q9UQB8,P40763,Q92542 26
Smooth muscle contraction 0.6232034106086414 1.2387627436990674 0.2154333748913657 1.0 0.5944044076973084 12 P04083,P09493,P60660,P14649 4
Extra nuclear estrogen signaling 0.6236235255784268 1.2311994116539573 0.2182482914171783 1.0 0.5944044076973084 14 Q9UBI6,P31751,P31749 3
Abc transporters in lipid homeostasis 0.6074405870702808 1.2285953324653602 0.2192235663684414 1.0 0.5944044076973084 3 P40855 1
Signaling by hippo 0.6116132556845582 1.2216414661135016 0.2218432404796222 1.0 0.5944044076973084 6 Q9UDY2,P62258 2
Ptk6 regulates proteins involved in rna processing 0.6022425494246155 1.2137388236486242 0.2248474739535217 1.0 0.5978898739218648 2 Q07666 1
Negative regulation of nmda receptor mediated neuronal transmission 0.6096341094074857 1.2121762379753505 0.2254449253409398 1.0 0.5983453216988271 6 Q13555,Q14168 2
Egfr downregulation 0.6123306504742565 1.210366697529888 0.2261382148134938 1.0 0.5990529313172555 8 P60953,P42566,Q92783,Q9UBC2,Q9Y6I3 5
Basigin interactions 0.6078020236583078 1.1957936065453658 0.2317771115094218 1.0 0.6082524571200528 7 P54709,P23229,P05556,P08195 4
Ion transport by p type atpases 0.6160559560273042 1.1894306091386586 0.2342702618220902 1.0 0.6125054890097108 15 Q13555,Q9NQ11,P54709,P20020,P35670,Q04656,P05026,P23634,Q8NB49 9
Mastl facilitates mitotic progression 0.5982293095336768 1.1755659174777962 0.2397683817708367 1.0 0.6222454861483452 4 P06493 1
Nr1h2 and nr1h3 mediated signaling 0.5993408185870854 1.1629592787071807 0.2448460245235479 1.0 0.6307592998735071 6 Q8NB78,Q9BZK7 2
Eph ephrin mediated repulsion of cells 0.6056686796862947 1.1528860463819703 0.2489571600854385 1.0 0.6332171245651372 12 Q92542 1
Clathrin mediated endocytosis 0.5575622341616439 1.1446602008970832 0.2523499439715262 1.0 0.6338132476314416 60 Q9Y6I3,P04114,Q9UQ16,O43493,Q9NVZ3,Q14108,P98164,O14657,Q9UBW8,P20645,Q9UNS2,P11717,P61160,P02786 14
Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects 0.5874889347890292 1.1441756211315457 0.2525508112784291 1.0 0.6338132476314416 2 P24941 1
Ptk6 regulates cell cycle 0.5874889347890292 1.1441756211315457 0.2525508112784291 1.0 0.6338132476314416 2 P24941 1
Cargo concentration in the er 0.6068770072628845 1.1438860043466363 0.2526709159968754 1.0 0.6338132476314416 15 Q12907,Q9Y6B6,Q13190,Q5JRA6,P53634 5
Diseases of metabolism 0.5890704384994775 1.138191756799687 0.2550404200069456 1.0 0.6360155411896121 47 Q99519,P10619,P34059,P08236,P06865,Q93063,P16278,P07686,P54802,P15586,Q9UHI8,O43505,P10253,Q8NCH0 14
Map3k8 tpl2 dependent mapk1 3 activation 0.5908576519903327 1.1313240199939634 0.2579187380207131 1.0 0.6397156521594506 5 O15111,Q9Y297 2
Signaling by type 1 insulin like growth factor 1 receptor igf1r 0.5942042648033226 1.1305545768588037 0.2582426150349348 1.0 0.6397156521594506 7 P31751 1
Tp53 regulates transcription of genes involved in g2 cell cycle arrest 0.5957096225828127 1.1303074280593546 0.2583467056797781 1.0 0.6397156521594506 8 Q86X55 1
Adora2b mediated anti inflammatory cytokines production 0.5880037342804637 1.0860024691171777 0.277477899853233 1.0 0.6716878817136882 9 Q9UBI6 1
Apoptotic cleavage of cell adhesion proteins 0.5822606001495709 1.0814003654648705 0.2795190591619405 1.0 0.6743037097308668 6 Q14126 1
G alpha i signalling events 0.5984765769392838 1.0771955841973175 0.2813928976312465 1.0 0.6764897587736184 27 P04083,Q9UBI6,P05067,P07602 4
Rhoc gtpase cycle 0.5964798857806923 1.0750495089641872 0.2823525631348578 1.0 0.6764897587736184 32 P41440,Q8TAA9,Q9UDY2,Q14254,P52565,O75955,Q13464,Q13190,P61586,P43121,P14923,Q14739,P27105,Q07021,P02786 15
Heme signaling 0.5820121787112087 1.0721533891425798 0.2836511420359318 1.0 0.6769061523379547 7 Q86X55,P04114 2
Interleukin 4 and interleukin 13 signaling 0.5891927416214064 1.0665882289343485 0.2861578182092832 1.0 0.6788515231096389 13 P04083,P40763,P31749 3
Inhibition of replication initiation of damaged dna by rb1 e2f1 0.5772031785772991 1.0664076862204592 0.2862393886616141 1.0 0.6788515231096389 5 P49643,P30154 2
Prolactin receptor signaling 0.5744796366892129 1.0629860864763343 0.287788261066956 1.0 0.6813738929814608 4 Q13616,Q9Y297 2
Antigen presentation folding assembly and peptide loading of class i mhc 0.591983392632618 1.061447548508384 0.2884865578823552 1.0 0.6818773186310214 17 P10321,Q9Y6B6,Q6P179,P01889,P04439 5
Signaling by insulin receptor 0.5910048797332522 1.056561239827829 0.2907118779639304 1.0 0.6839247116726216 17 Q15904,P61421,P31751,Q93050 4
Rnd1 gtpase cycle 0.5857289483204408 1.0391523745278386 0.2987338759565556 1.0 0.6944078838460334 15 Q8TAA9,O75976,P02786 3
Regulation of beta cell development 0.5681130052305825 1.0328950434562187 0.3016530185828343 1.0 0.7000344431244618 4 P31749 1
G alpha 12 13 signalling events 0.5706489438586744 1.017861324131773 0.308743863861149 1.0 0.7117838831872796 7 Q9UBI6,Q13464,P61586 3
Iron uptake and transport 0.5823154280643479 1.0092707921449395 0.3128447837811041 1.0 0.7200558629978201 18 Q15904,Q93050,P61421,P02786 4
Nef mediated downregulation of mhc class i complex cell surface expression 0.5622021426054195 1.005008189755891 0.3148929063311985 1.0 0.7229234784855981 4 Q9BXS5,P04439 2
Sema4d in semaphorin signaling 0.5711860693824566 0.9978431059572704 0.3183554439847489 1.0 0.7257454135539795 10 P35580,P60660,Q13464,P61586,P35579,O75116 6
Rho gtpases activate iqgaps 0.5709383113905528 0.996648556124486 0.3189351283210864 1.0 0.7257454135539795 10 P60953,Q13885,P46940,P04350,Q13576,Q9BUF5 6
Visual phototransduction 0.5698408859881559 0.9913586381685932 0.3215104895164167 1.0 0.7304218888042865 10 P98164,Q07954 2
Glutathione synthesis and recycling 0.5629317637824487 0.9894606397936784 0.3224378182660841 1.0 0.7313452291527981 6 Q8WUX2 1
Diseases associated with glycosylation precursor biosynthesis 0.5676795970193061 0.9809467341419944 0.3266190095079184 1.0 0.7372557706577452 10 Q99519,P10619 2
Foxo mediated transcription 0.5665634658676888 0.9755731453306534 0.3292760378497603 1.0 0.7408710851619608 10 Q96ST3,P31946,P31751,P31749 4
Programmed cell death 0.3193209634058754 0.9739916212243036 0.3300606994796531 1.0 0.7414483553110928 108 Q9UJU6,P28070,Q9Y3E7,O43293,Q14126,Q07021,P31751,P62258,P49721,P49720,P41440,Q9UDY2,P26583,O75955,P31749,Q04917,P31946,O00560,P40763,P28074,P28072 21
Post translational modification synthesis of gpi anchored proteins 0.5518277160261984 0.9283949597122804 0.3532027320885507 1.0 0.7772674543139894 7 O43292,Q9ULX3,Q9H490 3
Rhoa gtpase cycle 0.5502427292432753 0.9138608820254782 0.360789950683543 1.0 0.790013655373989 48 P41440,Q8TAA9,Q9UDY2,Q96HY6,P52565,O15173,O75955,P61586,Q13190,Q8NBN3,P43121,Q14739,Q9P0I2,P27105,Q15904,Q07021,P02786 17
Assembly and cell surface presentation of nmda receptors 0.5505169292256407 0.8986100060126088 0.368860427132061 1.0 0.8016718880702998 10 Q13555,Q15334,Q13885,Q14168,Q9BUF5 5
Mtorc1 mediated signalling 0.549082229448404 0.8917594077642991 0.3725219033823801 1.0 0.8081430744374957 10 P23588,Q6IAA8,P31946,P62942 4
Mtor signalling 0.5542662573777072 0.8845407773026641 0.3764043601607054 1.0 0.8125772161153412 15 P31751,P62942,P31749,P31946,P23588 5
Abortive elongation of hiv 1 transcript in the absence of tat 0.5511664027221195 0.875180548494733 0.381475675224098 1.0 0.8176974778849366 14 Q8IXH7,P18615 2
Signaling by notch1 pest domain mutants in cancer 0.5397580846137878 0.8714460251031447 0.3835106647368365 1.0 0.8208063617233513 7 Q92542 1
Cell cell junction organization 0.5445395175857691 0.8701066761992228 0.3842421095579698 1.0 0.8211201245348395 10 Q9BY67,Q9Y624 2
Transport of bile salts and organic acids metal ions and amine compounds 0.536696260866169 0.8657978684106056 0.3866010183449906 1.0 0.8241102278790886 6 Q9H2J7 1
Vitamin b2 riboflavin metabolism 0.5225730303924577 0.8411476663840874 0.4002652143983116 1.0 0.8463439171916107 2 P22413 1
Pi3k akt signaling in cancer 0.541807585678922 0.8362088254889892 0.4030374343139717 1.0 0.8483050113916493 13 P31751,P31749 2
Mhc class ii antigen presentation 0.521189015994976 0.8319727862573054 0.405424305480214 1.0 0.8483050113916493 56 Q9Y496,P07858,Q9Y6B6,P10619,Q99538,P53634,Q9NSK0 7
Small interfering rna sirna biogenesis 0.524516523984474 0.8289665428218805 0.4071233395067291 1.0 0.8493330886589118 4 Q15631 1
Metabolism of cofactors 0.529094827569401 0.8214970578281771 0.4113631992833344 1.0 0.8556354545093355 7 P00374,P31749 2
Chk1 chk2 cds1 mediated inactivation of cyclin b cdk1 complex 0.533284311054095 0.8092955827721022 0.4183451464360137 1.0 0.8637596847002401 11 P06493,P31946,P62258,Q04917 4
Retrograde transport at the trans golgi network 0.5417043420292984 0.7992145966239799 0.4241659895559695 1.0 0.864338242868768 20 O43752,P11717,O43493 3
Bicarbonate transporters 0.5113602832694024 0.7898841322132609 0.4295954390875227 1.0 0.8697861918826691 2 Q9Y6M7 1
Ros and rns production in phagocytes 0.524763469780362 0.7845447284889526 0.432720547268671 1.0 0.8697861918826691 9 P61421,Q93050 2
Intra golgi traffic 0.5376709517673023 0.7835265792342202 0.4333179517932062 1.0 0.8697861918826691 19 P39880,O00461,Q16706,Q13190,O43752,Q96MW5,Q8TBA6 7
Runx1 regulates expression of components of tight junctions 0.509884921805845 0.7831757936485821 0.4335238875529821 1.0 0.8697861918826691 2 Q13951 1
Regulation of tp53 activity through acetylation 0.5307036998947132 0.7647272130658714 0.4444339980759433 1.0 0.8825818009881533 16 Q8TBX8,P31749 2
Glycogen metabolism 0.5216133599640672 0.746999074352739 0.4550641195824187 1.0 0.8998732730897407 12 P10253,P46020 2
Asparagine n linked glycosylation 0.3078963313503347 0.7418392391041262 0.4581847432108019 1.0 0.903499128466244 128 Q99519,P04066,P10619,Q9Y6B6,O60512,O43731,P16278,Q13190,P15291,Q16706,P84085,P53634,Q11206 13
Collagen formation 0.5236762766157879 0.7369362174596151 0.4611611379949538 1.0 0.9055527800628184 15 P23229,P13674,P07858,O15460 4
Transcriptional regulation of white adipocyte differentiation 0.5213812000796132 0.7323166068815731 0.4639753454160304 1.0 0.9071748770879828 14 Q86X55,Q93074 2
Inla mediated entry of listeria monocytogenes into host cells 0.4980820300973865 0.7298598044606301 0.4654758841859954 1.0 0.9071748770879828 2 P35222 1
Signal transduction by l1 0.5121763350524036 0.7260592816036501 0.4678024294955125 1.0 0.9071748770879828 9 P06756,P05556 2
Platelet calcium homeostasis 0.5009715912986812 0.7213910590980169 0.4706689460063757 1.0 0.91021928401233 4 P20020,P23634 2
Reduction of cytosolic ca levels 0.5009715912986812 0.7213910590980169 0.4706689460063757 1.0 0.91021928401233 4 P20020,P23634 2
P75ntr negatively regulates cell cycle via sc1 0.4918855119504265 0.702143832649703 0.4825894692008967 1.0 0.9212074846253246 2 Q13547 1
Signaling by notch1 0.5027719860856557 0.6913562463029921 0.4893416930138059 1.0 0.9284266716099776 8 Q92542 1
Protein protein interactions at synapses 0.5122690817625813 0.6829498179564955 0.4946385527424077 1.0 0.9353422360844904 15 P41440,Q15334,O75955,Q9UJU6,Q14168,Q13136,P10586 7
Translation of sars cov 2 structural proteins 0.5140402006554636 0.6794369224044862 0.4968610619003737 1.0 0.936480506364777 17 Q10472,Q11206 2
Synthesis of diphthamide eef2 0.4881936245572626 0.6747871443901801 0.4998110091427215 1.0 0.9370710750537268 3 P13639,Q9BQC3 2
Transport to the golgi and subsequent modification 0.4023517369403696 0.6746396650871016 0.4999047259367817 1.0 0.9370710750537268 85 Q13190,Q16706,P24390,Q9BUF5,O15027,O95487,Q9Y6B6,P04066,Q12907,O60512,Q9Y2V7,Q9H9E3,P84085,P53634,Q96MW5,P35606,P49755,O43731,Q13885,P15291,Q92734,Q5JRA6,O14579,Q11206,Q14203,O94979,Q9UBF2,Q9Y678,Q99747,P04350,O95486 31
Adherens junctions interactions 0.4978670185339686 0.6690801402108675 0.5034443577959045 1.0 0.9386638964365784 8 Q9BY67 1
Thrombin signalling through proteinase activated receptors pars 0.495370961753854 0.6666547333667696 0.5049926992618756 1.0 0.9390857612763884 7 Q9UBI6 1
Interferon gamma signaling 0.5056129584497896 0.6652134984899388 0.5059139479820227 1.0 0.9395544748237564 13 P10321,P01889,P04439 3
Synthesis of substrates in n glycan biosythesis 0.5105077778889351 0.6472386593232371 0.5174774944607485 1.0 0.9490607657662512 20 Q99519,Q11206,P10619 3
Formation of the early elongation complex 0.5064990027798217 0.6438089916128942 0.5196993023653049 1.0 0.9490607657662512 17 Q8IXH7,P18615 2
Regulation of mecp2 expression and activity 0.4931693190419359 0.6310457255626487 0.5280106270457929 1.0 0.9594443597353196 10 Q96ST3,Q13555,Q9BZK7 3
Diseases of programmed cell death 0.5059740681680026 0.6093700548400431 0.5422791818941559 1.0 0.9723329115765796 24 Q07021,P05067,P07384,P17655 4
Deactivation of the beta catenin transactivating complex 0.491702736198826 0.608780554833719 0.5426699041660232 1.0 0.9723329115765796 12 P31751,P31749,Q9Y297 3
Antigen processing cross presentation 0.4849642636780265 0.6012668836336248 0.5476622429472515 1.0 0.9745472612141206 56 P10321,P28070,Q9UIQ6,P49721,P01889,Q9UBG0,P28074,P28072 8
Anti inflammatory response favouring leishmania parasite infection 0.4913542916189132 0.5998310233528332 0.5486188555608631 1.0 0.9750137635537364 13 Q9UBI6,P10644 2
Loss of function of mecp2 in rett syndrome 0.4722711750774614 0.5838360776885042 0.559330602904859 1.0 0.991540614240432 5 Q9BZK7 1
Post translational protein modification 0.2825190372587056 0.570503988573449 0.5683359176440321 1.0 0.9999293588624324 413 P05067,P16278,Q13190,Q06481,Q08431,Q9Y6B6,P04066,O60512,P28070,Q86SF2,O43493,Q9BTY2,Q10472,P53634,P04114,P10619,Q9HA64,O43731,P49721,P15291,Q5VTR2,Q9UHI8,P60604,O43505,Q11206,Q9BTE7,P04439,Q99519,Q9NXR7,O43852,Q9UBW8,P28074,P28072 33
Cd28 dependent vav1 pathway 0.4663480909254215 0.5687230140340087 0.5695441271253827 1.0 1.0 4 P60953,Q13177 2
Insertion of tail anchored proteins into the endoplasmic reticulum membrane 0.4814418668742954 0.5627209000562454 0.5736249501800597 1.0 1.0 12 P05067,P46379,Q13190 3
Signaling by notch3 0.4688376620192936 0.5588663136380967 0.576252960966293 1.0 1.0 6 Q92542 1
Intrinsic pathway for apoptosis 0.494520387353779 0.5581569121156341 0.5767372407041489 1.0 1.0 23 P31751,P62258,P31749,P31946,P40763,Q07021 6
Maturation of sars cov 2 nucleoprotein 0.463241806908775 0.5554442742244233 0.5785908163191633 1.0 1.0 4 Q99873,Q96SB4,P48729 3
Ion homeostasis 0.4769579048872506 0.550671646791533 0.5818587844089036 1.0 1.0 11 Q13555,P54709,P20020,P05026,P23634 5
Cardiac conduction 0.4769579048872506 0.550671646791533 0.5818587844089036 1.0 1.0 11 Q13555,P54709,P20020,P05026,P23634 5
Developmental biology 0.2856454056244929 0.5457753018529862 0.5852204025767596 1.0 1.0 265 Q15375,Q9BZK7,Q9UQ16,Q92859,P07384,P63220,Q14574,Q16539,P62857,P28070,Q93074,Q14126,P36896,O94813,P60660,P31751,P49721,A0MZ66,Q86X55,P61160,P06756,P31749,O00560,P40763,P28074,P28072,Q92542 27
Ctla4 inhibitory signaling 0.4700087560039167 0.5456068700538454 0.5853362009110725 1.0 1.0 8 P31749 1
Muscle contraction 0.4932355319823908 0.5415556229593746 0.5881246697392175 1.0 1.0 26 P04083,P60660,Q13555,P54709,P20020,P09493,P67936,P14649,P05026,P23634,Q13177 11
Regulation of runx1 expression and activity 0.4560212514757988 0.5355525447612407 0.5922678335496359 1.0 1.0 3 Q13951,Q06124 2
Toll like receptor cascades 0.4931149630833764 0.5335942001177493 0.5936223218361945 1.0 1.0 29 P07858,P04114,Q9UQ16,Q99538,P05067 5
Cross presentation of soluble exogenous antigens endosomes 0.4921556989947828 0.5292010703887582 0.5966659742382698 1.0 1.0 39 P28074,P49721,Q9UBG0,P28072 4
Signaling by met 0.4805499243003794 0.5182634384980797 0.6042744784960459 1.0 1.0 18 O14964,P05556,P40818,Q96S59,Q96N67,P42566,Q92783,P40763,P20338,Q06124 10
Activated ntrk2 signals through cdk5 0.4488049572145179 0.5163837339964036 0.6055864241634423 1.0 1.0 2 P63000 1
Cell junction organization 0.4821765632776804 0.5145851050176329 0.6068429757729996 1.0 1.0 20 P23229,Q96AC1,P05556,Q9BY67,P19022,P12814,Q9Y624 7
Signaling by ptk6 0.4671898371651232 0.5080762375636058 0.6113998790497581 1.0 1.0 11 P31749 1
Ngf stimulated transcription 0.4489374262101561 0.5060150856561173 0.6128460594430707 1.0 1.0 3 P50570,Q14839 2
Rhoj gtpase cycle 0.4831947968532034 0.5050781876104847 0.6135039209189512 1.0 1.0 23 Q5T0N5,Q8TAA9,P60953,P14923,Q6IAA8,P27105,P51149,P02786,Q13177 9
Antigen processing ubiquitination proteasome degradation 0.3414010089907772 0.4922747660266665 0.6225251162717038 1.0 1.0 94 Q9UIQ6,Q9C0C9,Q9H1A4,Q99436,Q9ULT8,P52888,P28070,Q9UJX4,P55786,O94822,Q9Y297,P49721,Q15386,P49720,P20618,P60604,Q13867,Q9UJX5,P46934,Q9GZZ9,Q13616,Q6UWE0,P28074,P28072 24
Cell death signalling via nrage nrif and nade 0.4588786723295754 0.4892423323403251 0.6246701427009442 1.0 1.0 9 Q92542 1
Cyclin a cdk2 associated events at s phase entry 0.4799662535373066 0.4796565316827444 0.6314716414796657 1.0 1.0 44 P28070,P49721,P31749,P28074,P28072 5
Signaling by vegf 0.4800746903992652 0.4760113211850825 0.6340663124191612 1.0 1.0 27 Q16539,P31751,P60953,P06756,Q7L576,Q13464,P61586,P31749,P14923,Q13685,Q9UQB8,Q13177 12
Carboxyterminal post translational modifications of tubulin 0.4462455072939882 0.4739107046116539 0.6355635853855868 1.0 1.0 5 Q13885,Q9BUF5 2
Cargo trafficking to the periciliary membrane 0.4725737101996802 0.4711806818939859 0.6375117128191152 1.0 1.0 20 Q8TAG9,O60645,A6NIH7 3
Fatty acyl coa biosynthesis 0.464586609569802 0.4601204687258539 0.6454297527845931 1.0 1.0 16 Q9UMR5 1
Adenylate cyclase inhibitory pathway 0.4346414871643547 0.4587206995567638 0.6464347475070258 1.0 1.0 2 P08754 1
Maturation of sars cov 2 spike protein 0.4548690639255962 0.447670645091378 0.6543909101443559 1.0 1.0 12 Q11206 1
Linoleic acid la metabolism 0.4311006196518105 0.4446301971305701 0.6565870212124132 1.0 1.0 2 O95864 1
Rhog gtpase cycle 0.475656316879625 0.4415384121703749 0.6588232593649035 1.0 1.0 35 P05556,Q8TAA9,O75489,P52565,Q7L576,Q13190,P43121,Q6IAA8,Q14739,Q13576,Q14126,P02786 12
Runx3 regulates p14 arf 0.4324085005903189 0.4390155844514021 0.6606502440577804 1.0 1.0 3 Q13951,P25440 2
Rnd2 gtpase cycle 0.4609228880962508 0.4314959638776548 0.6661077867073713 1.0 1.0 18 Q8TAA9,P02786 2
Diseases of signal transduction by growth factor receptors and second messengers 0.2887041722815285 0.4230090609968367 0.6722886501478413 1.0 1.0 151 O15111,Q9BZK7,P21359,Q9NRY5,P28070,P67936,P51797,Q13555,P31751,P49721,P62942,P56545,P49720,Q14203,P10644,P13984,P31749,P31946,P40763,P28074,P28072,Q92542 22
Signaling by rho gtpases miro gtpases and rhobtb3 0.2795774253361188 0.4214647290095159 0.6734157614773566 1.0 1.0 262 Q96AC1,P05556,Q8NBT2,Q15334,Q14254,P63104,Q7L576,Q96N67,Q13190,P51648,Q14739,O75976,Q9P2R3,O15511,Q13576,Q9NSK0,P46060,Q9P258,P02786,Q9BUF5,P30154,Q16539,Q96HY6,P67936,Q13464,P61586,Q8NBN3,P12814,Q92783,Q14126,Q15904,Q07021,Q5T0N5,P35580,P53350,P60660,Q8TAA9,P60953,P62258,Q9BX68,Q8IYB3,Q13885,O14777,P43121,Q6IAA8,Q5VTR2,Q68EM7,P15924,P27105,Q8NFH3,P61160,P41440,Q9Y512,Q9UDY2,O75489,P52565,P43034,O75955,Q04917,Q9P0I2,P14923,Q9BT78,P31946,P04350,Q9UQB8,Q9BW27,Q96RT1,O15173 68
Met promotes cell motility 0.4380276534411498 0.4211978259876832 0.6736106317367192 1.0 1.0 7 P05556 1
Cell cell communication 0.4695087874254849 0.4185586719503996 0.6755386987658103 1.0 1.0 30 Q08722,Q96AC1,P05556,P23229,Q9BY67,Q9Y5K6,P19022,P12814,Q9Y624 9
Condensation of prometaphase chromosomes 0.4430190043957746 0.4149781639430989 0.6781578883232444 1.0 1.0 10 P67870,P19784,Q9NTJ3,P06493 4
Regulation of tp53 expression and degradation 0.4468352417148709 0.4143035700024971 0.6786517996732973 1.0 1.0 12 P31751,P31749,P06493 3
Signaling by notch 0.4451065010993801 0.4136374910424824 0.679139612145663 1.0 1.0 61 P28070,P49721,P67809,P31749,P15291,P28072,P28074,Q11206,Q92542 9
Hdr through mmej alt nhej 0.4383683121489548 0.4135271997799413 0.6792203985086553 1.0 1.0 8 Q92878,P18887,P49916,O60934,P49959,Q9UGN5,P39748 7
Cdc42 gtpase cycle 0.4695660663411648 0.4124862369369538 0.6799830664304989 1.0 1.0 34 Q5T0N5,Q8TAA9,P60953,P52565,Q96N67,Q68EM7,Q6IAA8,P14923,Q14739,P27105,Q9UQB8,Q13576,P51149,P02786 14
Hdms demethylate histones 0.4325939498418137 0.4088850455770352 0.6826240240187038 1.0 1.0 6 Q8NB78,Q7LBC6 2
Regulation of tp53 activity through methylation 0.4219327110293139 0.3876799770121329 0.6982528751989807 1.0 1.0 4 Q9H9B1 1
Interleukin 1 family signaling 0.4563590689711681 0.3868363468664731 0.6988773671012019 1.0 1.0 51 O15111,Q9Y297,P28070,P49721,P05067,Q9H3S7,P49720,P20618,P40763,Q13616,P28074,P28072 12
Cyclin d associated events in g1 0.4315696127697113 0.3865725925424668 0.6990726514216934 1.0 1.0 8 P30154,P42771,P63208,P24941,P11802,Q13616,P63151 7
Condensation of prophase chromosomes 0.4305352393989808 0.3825216273463843 0.7020744901116216 1.0 1.0 8 P53350,P06493,P42695,Q01105 4
Class i peroxisomal membrane protein import 0.4362900171780437 0.3796757614631593 0.7041861147571018 1.0 1.0 11 Q9NR77,P51648,P40855,P56589 4
Signaling by alk 0.4233486956082876 0.3729412899258176 0.7091921403910413 1.0 1.0 6 P40763 1
Interleukin 1 signaling 0.4562970184845238 0.3699973300112559 0.7113844797995277 1.0 1.0 48 P28072,P49721,P28074,P05067 4
Semaphorin interactions 0.4463606021740351 0.3637185524172457 0.7160681880724553 1.0 1.0 19 P35580,P05556,P60660,Q13464,P61586,Q9Y490,P35579,O75116,Q13177 9
Cooperation of pdcl phlp1 and tric cct in g protein beta folding 0.4376814099471979 0.3619502225070448 0.7173892285748227 1.0 1.0 14 Q9UBI6,P19784 2
Ire1alpha activates chaperones 0.4546848704664374 0.3602655554931536 0.7186485550281441 1.0 1.0 27 P51858,P61421,O43909,O43731,O14773,Q14203 6
Ca dependent events 0.4232264565154856 0.3542912197562343 0.7231206471921536 1.0 1.0 8 P10644 1
Rhoq gtpase cycle 0.4470807231515399 0.3498448043272335 0.7264551721678032 1.0 1.0 22 P02786 1
Signalling to erks 0.4283847822946418 0.3486454481061179 0.7273555033942931 1.0 1.0 11 P31946,P11234,Q16539,P11233 4
Signaling by notch4 0.4548128773309879 0.3478967959509097 0.7279176916132428 1.0 1.0 44 P49721,P31749,P28074,P28072,Q92542 5
Nephrin family interactions 0.4214795764484307 0.3476488514789988 0.7281039137964422 1.0 1.0 8 Q9Y5K6,P46940,O43707,P12814,Q13813 5
Signaling by erbb2 0.4315368581212631 0.3451445206677601 0.7299857248565018 1.0 1.0 13 P31749 1
Interleukin receptor shc signaling 0.4048391856004754 0.3447908504584942 0.7302516120561562 1.0 1.0 2 O00459 1
Role of lat2 ntal lab on calcium mobilization 0.4048391856004754 0.3447908504584942 0.7302516120561562 1.0 1.0 2 O00459 1
Pi 3k cascade fgfr1 0.4048391856004719 0.3447908504584818 0.7302516120561655 1.0 1.0 2 Q06124 1
Pi 3k cascade fgfr3 0.4048391856004719 0.3447908504584818 0.7302516120561655 1.0 1.0 2 Q06124 1
Activated ntrk2 signals through frs2 and frs3 0.4048391856004719 0.3447908504584818 0.7302516120561655 1.0 1.0 2 Q06124 1
Frs mediated fgfr3 signaling 0.4048391856004719 0.3447908504584818 0.7302516120561655 1.0 1.0 2 Q06124 1
Signaling by flt3 itd and tkd mutants 0.4048391856004719 0.3447908504584818 0.7302516120561655 1.0 1.0 2 Q06124 1
Pi 3k cascade fgfr4 0.4048391856004719 0.3447908504584818 0.7302516120561655 1.0 1.0 2 Q06124 1
Stat5 activation 0.4048391856004719 0.3447908504584818 0.7302516120561655 1.0 1.0 2 Q06124 1
Pi 3k cascade fgfr2 0.4048391856004719 0.3447908504584818 0.7302516120561655 1.0 1.0 2 Q06124 1
Stat5 activation downstream of flt3 itd mutants 0.4048391856004719 0.3447908504584818 0.7302516120561655 1.0 1.0 2 Q06124 1
Frs mediated fgfr1 signaling 0.4048391856004719 0.3447908504584818 0.7302516120561655 1.0 1.0 2 Q06124 1
Frs mediated fgfr2 signaling 0.4048391856004719 0.3447908504584818 0.7302516120561655 1.0 1.0 2 Q06124 1
Frs mediated fgfr4 signaling 0.4048391856004719 0.3447908504584818 0.7302516120561655 1.0 1.0 2 Q06124 1
Grb2 sos provides linkage to mapk signaling for integrins 0.4048391856004716 0.3447908504584803 0.7302516120561666 1.0 1.0 2 Q9Y490 1
Shc1 events in erbb2 signaling 0.4048391856004715 0.3447908504584797 0.7302516120561671 1.0 1.0 2 Q05655 1
Tie2 signaling 0.4049586776859521 0.3347663468475296 0.7378013484841255 1.0 1.0 3 Q06124,O00459 2
Apoptosis 0.3259082475000481 0.3345771683096368 0.7379440702822144 1.0 1.0 94 Q9UDY2,P31751,P62258,P28070,P49721,P26583,Q9UJU6,P49720,P31749,Q04917,Q07021,O43293,P31946,P40763,Q14126,P28074,P28072 17
Regulation of ras by gaps 0.4522371326294241 0.3286523978113715 0.7424184382934138 1.0 1.0 40 P21359,P49721,P28074,P28072 4
Copi independent golgi to er retrograde traffic 0.447373076050312 0.3284520646126034 0.7425698825078668 1.0 1.0 27 Q8TD16,Q13885,Q15102,P43034,Q9NP72,P68402,Q10472,P04350,Q10471,Q9H2M9,Q9BUF5,Q14203 12
Constitutive signaling by overexpressed erbb2 0.4050782403306884 0.3249898145330167 0.7451887804715989 1.0 1.0 4 Q96RT1,Q16543,P07900 3
Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein 0.4415607812397653 0.3217013034122148 0.7476789903217504 1.0 1.0 23 Q99519,Q11206,P10619 3
Rac1 gtpase cycle 0.4496683055006893 0.3199579087755098 0.7490002384861669 1.0 1.0 43 Q96AC1,P05556,Q8TAA9,Q7L576,Q96N67,Q68EM7,P43121,Q6IAA8,Q14739,Q9UQB8,Q13576,P02786 12
Rac3 gtpase cycle 0.4489691691883482 0.3148432916863782 0.752880640006468 1.0 1.0 35 Q96AC1,P05556,Q8TAA9,Q7L576,Q68EM7,P43121,Q6IAA8,Q14739,Q9UQB8,Q14126,P02786 11
Metabolism of folate and pterines 0.411841026342152 0.3031215305888555 0.7617972465413723 1.0 1.0 9 P00374,P34896 2
Signaling by egfr 0.4161032942175567 0.2941709119255588 0.7686273066796785 1.0 1.0 12 P60953,P42566,Q92783,Q9UBC2,Q13685,Q06124,Q9Y6I3 7
Sema4d mediated inhibition of cell attachment and migration 0.3952380205605884 0.2902541382727611 0.7716218215840775 1.0 1.0 4 P61586 1
Inlb mediated entry of listeria monocytogenes into host cell 0.400810610504466 0.2901408407462868 0.7717084925277811 1.0 1.0 6 P42566,Q92783 2
Met activates ptpn11 0.3916765053128656 0.2880246963818328 0.7733278343589864 1.0 1.0 3 P62993,Q06124 2
Pre notch expression and processing 0.4097340398055564 0.2789094277342072 0.7803143332495004 1.0 1.0 11 Q11206 1
Negative regulation of the pi3k akt network 0.4210181050556118 0.2694522250505742 0.7875817018876945 1.0 1.0 18 Q8TBX8,P31749 2
Slc mediated transmembrane transport 0.4311190356939103 0.2694345203473174 0.7875953246093252 1.0 1.0 25 Q9H2J7,P08195,P30825,Q9UBX3,Q8TAD4,Q70HW3,Q99808 7
Cell extracellular matrix interactions 0.3961669173241925 0.2650878535681059 0.7909417841687687 1.0 1.0 7 Q96AC1,P05556 2
Nrage signals death through jnk 0.3898405197873674 0.2621016931670603 0.7932430414433922 1.0 1.0 5 Q92974,P63000,Q14344,Q9NY61 4
Platelet activation signaling and aggregation 0.421640703349173 0.2620122792408725 0.7933119753492213 1.0 1.0 60 P07602,P13473,P05067,P31749,O43852,Q9UBI6,Q06481,Q92520,Q08380 9
Inositol phosphate metabolism 0.3946678707224149 0.2599764966839483 0.7948819033281154 1.0 1.0 7 Q13572 1
Death receptor signalling 0.4243272503402004 0.2580559846480361 0.7963637004658368 1.0 1.0 22 Q8TCT8,O15111,P62258,P61586,Q92542 5
Ripk1 mediated regulated necrosis 0.4024878812099881 0.2532517176067649 0.800073703864328 1.0 1.0 11 P41440,O00560,O75955 3
Negative regulation of notch4 signaling 0.4342077134527048 0.244855881289734 0.8065680235567492 1.0 1.0 42 P49721,P28074,P28072,P31749 4
Listeria monocytogenes entry into host cells 0.3922553946201429 0.243177243514487 0.8078680948605053 1.0 1.0 8 O14964,P62993,Q99961,O60716,P35222,P42566,Q92783 7
Translocation of slc2a4 glut4 to the plasma membrane 0.4317815712564509 0.2346145812767419 0.8145078911859982 1.0 1.0 38 O60343,P61106,O60645,Q9UPT5,Q9Y496,P31751,P62258,P63104,Q8TAG9,Q9UIQ6,Q13885,P31749,Q04917,P11233,P31946,P04350,P20338,Q9BUF5 18
Rnd3 gtpase cycle 0.4124893927490085 0.2314783355959316 0.8169432141343465 1.0 1.0 19 O75976 1
Cd209 dc sign signaling 0.370315727353197 0.2284617635045269 0.8192872784131688 1.0 1.0 2 Q13177 1
Phosphorylation of the apc c 0.3975538576780142 0.228419475156041 0.819320150625392 1.0 1.0 12 P53350,Q9UJX4,Q9UJX5,P06493 4
Clec7a dectin 1 induces nfat activation 0.3691354381823535 0.224829580308471 0.8221118533671399 1.0 1.0 2 Q08209 1
Leishmania infection 0.4275795654878773 0.2191716601876538 0.8265163306877912 1.0 1.0 36 Q16539,P10644,P05067,Q9UBI6,Q9UQB8 5
Response of eif2ak1 hri to heme deficiency 0.3686540731995334 0.2136649780333857 0.8308083241030082 1.0 1.0 3 P08243,P20042 2
Endosomal sorting complex required for transport escrt 0.3943291857056081 0.2099572242584519 0.8337010589564486 1.0 1.0 13 Q9UN37,Q92783,Q9Y3E7,Q9BRG1 4
Post chaperonin tubulin folding pathway 0.3836222623733821 0.2066383135989211 0.8362923360552434 1.0 1.0 9 P68371,Q13885,Q9BTW9,P04350,Q9BUF5 5
Regulation of ifng signaling 0.3659976387249131 0.2056721280918728 0.83704703164429 1.0 1.0 3 P42224,Q06124 2
Regulation of ifna signaling 0.3659976387249131 0.2056721280918728 0.83704703164429 1.0 1.0 3 P42224,Q06124 2
Wax and plasmalogen biosynthesis 0.3652199586654844 0.1939742437155947 0.8461960493910565 1.0 1.0 4 O15228,Q8WVX9,Q6IAN0 3
Eph ephrin signaling 0.4178731767551946 0.1928058149569803 0.8471110492624827 1.0 1.0 31 Q15375,P35580,P60660,P59998,P60953,Q13464,P61586,O00560,O15511,P61160,Q92542,O75116,Q13177 13
Rhoh gtpase cycle 0.4065998551600845 0.192404251671842 0.8474255622698572 1.0 1.0 22 Q8TAA9,P52565,Q13464,P14923,Q6IAA8,O75116,P27105,P51149,P02786,Q13177 10
Dna replication initiation 0.3736500930120414 0.1923361811871593 0.8474788789486347 1.0 1.0 7 P49643,Q9NRF9,P49642 3
Platelet sensitization by ldl 0.3744970278293841 0.1865501520238394 0.8520133534138925 1.0 1.0 8 P04114,Q16539 2
E2f mediated regulation of dna replication 0.3763903656023042 0.1841228962608258 0.8539170449221682 1.0 1.0 9 P49643,P30154,P49642,P06493 4
Rho gtpases activate cit 0.3779966392336619 0.1810165044258762 0.8563546213585573 1.0 1.0 10 P35580,P60660,Q15334,P61586 4
Ovarian tumor domain proteases 0.3686314134807285 0.177353201546615 0.8592309642759126 1.0 1.0 7 P06493 1
Vxpx cargo targeting to cilium 0.3736747326338193 0.1679628630136384 0.8666124949816059 1.0 1.0 10 O60645 1
Negative regulation of met activity 0.3665385752290701 0.1630384210149791 0.8704881837814082 1.0 1.0 8 O14964,P62993,P40818,Q99961,Q9NWH9,P42566,Q92783 7
Regulation of runx3 expression and activity 0.4141694597032031 0.1588521310199525 0.8737853756065108 1.0 1.0 39 P49721,P28074,P28072 3
Sars cov 1 infection 0.3829477389168776 0.1588411083323637 0.8737940601790473 1.0 1.0 15 Q10472,Q11206 2
Rac2 gtpase cycle 0.4119060369739182 0.1576470695249265 0.8747349111830025 1.0 1.0 35 P05556,Q8TAA9,P60953,Q9Y512,P52565,Q7L576,O15173,Q68EM7,P43121,Q6IAA8,Q14739,Q96RT1,Q14126,P51149,P02786,Q13177 16
Hedgehog on state 0.4144935389975898 0.157638875881687 0.874741368033326 1.0 1.0 44 P49721,P28074,P28072,P28070 4
Insulin processing 0.3770718460107837 0.1553110029310855 0.8765761417847115 1.0 1.0 13 Q8TAG9,O60645,Q8TAD4,Q8NEW0 4
Sealing of the nuclear envelope ne by escrt iii 0.3697981504822164 0.1413321940011862 0.8876075177308107 1.0 1.0 12 Q9Y3E7,Q13885,P04350,Q8WUX9,Q9UN37,Q9BUF5 6
Degradation of axin 0.4083706815989292 0.1372666910751816 0.8908199978482385 1.0 1.0 38 P49721,P28074,P28072 3
Transcriptional regulation by runx2 0.4064937184465891 0.1353410759333703 0.8923422099275926 1.0 1.0 52 P28070,P49721,P31749,P28074,P28072 5
Rho gtpases activate rocks 0.3622778150006679 0.1352638756049483 0.8924032456300002 1.0 1.0 10 P35580,P60660,Q13464,P61586,O75116 5
Circadian clock 0.3700415305303955 0.1346858437662744 0.8928602662355827 1.0 1.0 13 Q9BZK7,Q9Y297,Q9BWF3,Q13616,Q86X55,P50416 6
Degradation of dvl 0.4065450737518249 0.1283850137304827 0.8978442903194719 1.0 1.0 39 P49721,P28074,P28072 3
Regulation of pten stability and activity 0.4073202738105229 0.1278613902086234 0.8982586663363912 1.0 1.0 46 P31751,P28070,P46934,P49721,P31749,P19784,P28074,P28072 8
Metabolism of steroids 0.4061137501706751 0.1235244165644245 0.901691840724955 1.0 1.0 47 Q9UBM7,Q9Y6B6,Q9BZK7,Q99538,P04062,Q15392,O95772,P98164,Q86X55,P48449 10
Scf skp2 mediated degradation of p27 p21 0.405732383162472 0.1224675758155358 0.9025287234148278 1.0 1.0 41 P49721,P28074,P28072 3
Free fatty acids regulate insulin secretion 0.3371715382344299 0.1188559865667805 0.9053894521350234 1.0 1.0 4 O95573,O60488,P29992 3
Hedgehog off state 0.3999907198378411 0.1118545812418815 0.9109387094456152 1.0 1.0 54 Q9Y496,Q9Y297,P28070,Q8NCM8,P49721,Q13885,P10644,P49720,P51665,P20618,Q99436,Q13616,P28074,P28072,Q9BUF5 15
Neurexins and neuroligins 0.3472911349588249 0.1112580277847047 0.911411737682321 1.0 1.0 8 Q14168,Q9UJU6,Q15334 3
Asymmetric localization of pcp proteins 0.4000741532171767 0.1035508304372996 0.9175258094270446 1.0 1.0 39 P49721,P28074,P28072 3
E3 ubiquitin ligases ubiquitinate target proteins 0.3705711724359748 0.1020312850302829 0.9187318427961731 1.0 1.0 18 Q5VTR2 1
Polo like kinase mediated events 0.3367799113737106 0.1013194236831908 0.9192968976669418 1.0 1.0 6 Q99640,P53350,P30307,Q09028,P14635 5
G protein mediated events 0.357643523455001 0.1007363952209235 0.9197597191063184 1.0 1.0 13 P10644,Q13555 2
Intracellular signaling by second messengers 0.292947756905742 0.1006349611156713 0.9198402426188048 1.0 1.0 96 O15111,Q13555,P31751,P28070,P46934,P49721,P10644,Q8TBX8,P31749,P19784,P28074,P28072 12
Opioid signalling 0.3759543921229358 0.098948437913909 0.9211792096857488 1.0 1.0 21 Q9UBI6,P10644,Q13555,P29992 4
G1 s specific transcription 0.347615918006147 0.097005229826911 0.922722241238183 1.0 1.0 10 P00374,P06493 2
Signaling by interleukins 0.253392510091697 0.0962906000900339 0.9232897764385916 1.0 1.0 109 P04083,P05556,Q13277,Q16539,P28070,P49721,P05067,P31749,P40763,Q13126,P28074,P28072 12
Downstream signaling events of b cell receptor bcr 0.3951644946096164 0.0784616997218325 0.9374607954587972 1.0 1.0 44 O15111,Q9Y297,P28070,P49721,P62942,P49720,P20618,Q13616,P28074,P28072 10
Costimulation by the cd28 family 0.3541345000719472 0.0779784239980058 0.9378452158783248 1.0 1.0 15 P31749 1
Notch1 intracellular domain regulates transcription 0.3256018866870629 0.0764890678368738 0.9390300110985031 1.0 1.0 6 Q9BZK7 1
Intraflagellar transport 0.3448663673153541 0.0760105335158848 0.939410717910412 1.0 1.0 12 Q9Y496,Q13885,Q9BUF5,Q8NCM8 4
Sensory perception 0.3801572480707391 0.0740603695843442 0.9409623491137182 1.0 1.0 28 P98164,Q07954 2
Auf1 hnrnp d0 binds and destabilizes mrna 0.3929649306930715 0.0721454277656194 0.9424861742623096 1.0 1.0 42 P49721,P28074,P28072 3
Stabilization of p53 0.3921618381772686 0.0706895418741514 0.9436448443906646 1.0 1.0 41 P49721,P28074,P28072 3
Purine salvage 0.3189604252805704 0.0706127326971246 0.9437059764836097 1.0 1.0 5 P00491,P55263,P07741,P00492 4
Metabolism of polyamines 0.3907575649204265 0.0674295653655579 0.9462397329857246 1.0 1.0 40 P49721,P28074,P28072 3
Cdt1 association with the cdc6 orc origin complex 0.3900631337409987 0.0649523678626506 0.9482119250612278 1.0 1.0 40 P49721,P28074,P28072 3
Apc c cdc20 mediated degradation of cyclin b 0.3360020775546481 0.0627983961273727 0.9499270430550156 1.0 1.0 11 Q9UJX4,Q9UJX5,P06493 3
Rho gtpases activate paks 0.3357349428683132 0.0622125208470068 0.9503935916115328 1.0 1.0 11 P35580,P60660,P60953,Q14247,P35579,Q13177 6
Protein ubiquitination 0.3710742736891383 0.0522467348418813 0.9583320947405692 1.0 1.0 27 Q5VTR2,P60604 2
Signaling by gpcr 0.3881805915661124 0.0507160217244118 0.9595518095888372 1.0 1.0 46 P04083,P31751,P07602,Q9BYT8,P05067,P31749,P42892,Q9UBI6 8
Dna damage recognition in gg ner 0.3501960609133418 0.0489618424909234 0.9609497047293069 1.0 1.0 18 Q13619,Q9UBW8,Q9UNS2,Q9BT78 4
Sumoylation of dna methylation proteins 0.3029229406554541 0.048407391229546 0.9613915688630136 1.0 1.0 4 Q9HC52,P26358,Q8IXK0 3
G1 s dna damage checkpoints 0.386098444247685 0.0457434281909812 0.9635147493270916 1.0 1.0 43 P49721,P28074,P28072 3
Ksrp khsrp binds and destabilizes mrna 0.3382068791580755 0.0407652081124394 0.9674830761943788 1.0 1.0 15 P31749 1
Dag and ip3 signaling 0.3180546552800343 0.0401272385976724 0.9679916860250256 1.0 1.0 9 P10644 1
Rhod gtpase cycle 0.3701514899758307 0.0400194657754495 0.9680776072788706 1.0 1.0 29 Q8TAA9,Q9BX68,Q68EM7,P43121,P12814,Q14739,O15173 7
Copii mediated vesicle transport 0.3714718829696752 0.0348136137628779 0.9722283649994798 1.0 1.0 31 O15027,Q12907,Q9Y6B6,Q13190,P53634 5
Meiotic recombination 0.3184592005187819 0.0341302642601315 0.9727732751482184 1.0 1.0 10 Q13472 1
P75 ntr receptor mediated signalling 0.3318237804727334 0.0337942363862641 0.9730412320196038 1.0 1.0 14 Q92542,P62258,P61586 3
Darpp 32 events 0.3177391853260441 0.0328015346698691 0.9738328543831204 1.0 1.0 10 P10644 1
Ra biosynthesis pathway 0.2970058303538938 0.0315258647284519 0.974850165323096 1.0 1.0 5 O94788,Q8TC12,Q9BTZ2 3
Mitotic g1 phase and g1 s transition 0.3517445290656868 0.0288355812048847 0.9769957229729164 1.0 1.0 75 Q99436,O00231,P31350,P30154,P28070,P33993,Q9NRF9,P31751,P49721,P49720,P51665,P06493,P20618,P49643,P00374,P31749,P15927,Q13616,P28074,P28072 20
Pentose phosphate pathway 0.3037825059101703 0.0286328285718512 0.9771574293975964 1.0 1.0 7 P29401,Q96G03,P52209,P11413,O95336,P11908 6
Signaling by the b cell receptor bcr 0.3819110061811459 0.0275256026042179 0.9780405196558914 1.0 1.0 46 O15111,Q9Y297,P28070,P49721,P62942,P49720,P20618,Q13616,P28074,P28072 10
Unwinding of dna 0.3131538184877855 0.0245901593492496 0.9803818686294676 1.0 1.0 10 P33993,Q9BRT9,Q9BRX5 3
Butyrate response factor 1 brf1 binds and destabilizes mrna 0.322537842694307 0.0220640230466113 0.982396884934842 1.0 1.0 13 P31749 1
Formation of tc ner pre incision complex 0.3635908308101243 0.0220216188534659 0.982430710367214 1.0 1.0 29 Q13619,Q9UNP9,Q9UBW8,Q9BT78,Q9ULR0,Q9UNS2 6
Transcriptional regulation by runx3 0.3792479009633618 0.0218354582495874 0.982579209330706 1.0 1.0 43 P49721,P28074,P28072 3
Formation of tubulin folding intermediates by cct tric 0.3187333530630457 0.0214945687154021 0.9828511360006738 1.0 1.0 12 P50991,Q99832,P68371,P17987,Q13885,P49368,P40227,P78371,P04350,P48643,Q9BUF5 11
Hiv transcription initiation 0.3238987806853678 0.0182468550434911 0.9854419239284432 1.0 1.0 14 Q00403 1
Rho gtpases activate pkns 0.3330198134032324 0.011265678163048 0.9910114794575686 1.0 1.0 18 P60660,P62258,P63104,Q04917,P61586,P31946 6
Transcriptional regulation by mecp2 0.3225889895248611 0.0095680867554987 0.9923658877831888 1.0 1.0 15 Q96ST3,Q14739,Q13555,Q9BZK7 4
Regulation of runx2 expression and activity 0.3751438889264937 0.0081172532468011 0.9935234400815351 1.0 1.0 43 P49721,P28074,P28072 3
Fceri mediated nf kb activation 0.3737618099823567 0.0018192130330816 0.9985484788087364 1.0 1.0 44 P25786,O15111,P61088,P28070,Q9Y297,P49721,P28074,P49720,P51665,P20618,Q99436,Q15008,Q13616,O14818,P28072,O00231 16