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0723187 verified
Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
Protein localization 0.6029747975753831 4.455167713186714 8.382763786896064e-06 0.0116176099981158 0.0116855727189345 81 O14975,Q9Y584,P40855,Q10713,Q92968,P12236,Q9NR77,Q8N4H5,Q9Y5Y5,Q9NS69,Q13505,O14925,P09601,Q15388,Q5T8D3,P50402,Q9Y5J6,P51648,P56589,P33897,P21796,Q9Y512,O75381,O75746,O75431,O15254,Q8NBU5,O60830,P46379,Q13190,O15228,P62072,O43615,Q15067,O96008,O14734,Q99595,Q2T9J0,O43808,Q3ZCQ8,Q8TB36,P12235,P28288,Q9Y5J9 44
Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins 0.6060755949638273 4.127959512029934 3.659965362490247e-05 0.0497411433614842 0.0255099585765577 70 O14949,Q9P0S2,P09669,Q9UDW1,O95139,O43676,P21912,Q9NPL8,O75880,Q86Y39,O75306,P13073,O75964,O43674,P00846,Q9Y6M9,Q9Y6N1,P03886,P56385,O14548,Q8TB37,Q99643,P24539,O96000,Q8N8Q8,P00403,O95167,Q9NX14 28
Respiratory electron transport 0.6150965430109283 3.9593712821248768 7.514733311642097e-05 0.0994587599730733 0.0310554766087822 60 O14949,Q9P0S2,P09669,Q9UDW1,O95139,O43676,P21912,Q9NPL8,O75880,Q86Y39,O75306,P13073,O43674,Q9Y6M9,Q9Y6N1,P03886,O14548,Q8TB37,Q99643,O96000,Q8N8Q8,P00403,O95167,Q9NX14,Q9BU61 25
Mitochondrial protein import 0.6898247200891051 3.906910699781152 9.348368326089762e-05 0.1221875740728818 0.0310554766087822 36 Q9Y584,Q10713,P12236,Q8N4H5,Q9NS69,Q13505,O14925,Q15388,Q9Y5J6,P21796,Q9Y512,O75431,O60830,P62072,O43615,O96008,Q99595,P12235,Q9Y5J9 19
Phospholipid metabolism 0.6136454919671023 3.823397670663939 0.0001316252324929 0.1676461689159743 0.0310554766087822 54 Q9C0D9,Q8NF37,Q8WUK0,Q10713,Q6P1A2,Q9BTU6,Q53H12,Q8NAN2,Q8TBX8,O15120,Q9BZF1,Q9NP80,Q8N9F7,P43304,Q9UG56,P20339,Q9BVG9,Q8IV08,Q9NQZ5,Q9NTJ5,P48739,O95674,Q9HBU6,Q9NPH0,Q9C0I1,Q9NUQ2,Q8N2A8,Q99829,O15228,O14735,P48651,Q92604,Q96N66 33
Glycerophospholipid biosynthesis 0.6430245511077999 3.648377661100596 0.0002639015160785 0.307832474527755 0.0525541019162201 38 Q9C0D9,Q8NF37,Q8WUK0,Q6P1A2,Q53H12,Q8NAN2,O15120,Q9BZF1,Q9NP80,P43304,Q9UG56,Q9BVG9,Q8IV08,Q9NQZ5,P48739,O95674,Q9HBU6,Q9NPH0,Q9NUQ2,Q8N2A8,Q99829,O15228,O14735,P48651,Q92604,Q96N66 26
The citric acid tca cycle and respiratory electron transport 0.5014879887389687 3.36203455202315 0.0007737044163294 0.6600515902149792 0.1034623712645587 103 O14949,Q9P0S2,P09669,Q9UDW1,Q13423,O95139,O43676,P21912,Q9NPL8,O75880,Q86Y39,O75306,P13073,O75964,P00846,O43674,Q9Y6M9,Q9Y6N1,P03886,P56385,O14548,P21796,Q8TB37,Q99643,P24539,Q9H9P8,O96000,Q8N8Q8,P00403,O95167,Q9NX14,Q9BU61 32
Mitochondrial calcium ion transport 0.7469005807674013 3.3471678632226616 0.0008164175637805 0.6797171968588811 0.1034623712645587 18 Q9H300,P45880,Q9Y277,Q96TA2,Q9H4I9,P21796,Q10713,Q8WWC4,Q8IYU8,Q99623,Q9BPX6,P35232,O95202,Q9Y4W6 14
Slc mediated transmembrane transport 0.7069723531578351 3.3127883722306253 0.0009237084553235 0.7242455986516486 0.1073041322267495 22 P11166,Q8TB61,Q9H936,O00400,P05141,P12236,P30825,Q70HW3,P12235,Q9Y6M7,Q9H2J7,P35613,Q9UBX3 13
Class i peroxisomal membrane protein import 0.8069847209229873 3.115438346387862 0.0018367174019984 0.9229066529881303 0.1152806315909842 13 P40855,P33897,Q92968,O43808,Q8TB36,Q5T8D3,O75381,Q9NR77,Q8NBU5,Q9Y5Y5,P51648,P56589 12
Cristae formation 0.6833235784881794 3.101622640753559 0.0019246313033312 0.9318143526496848 0.1152806315909842 21 Q9BUR5,Q9NVH1,O75964,P00846,Q6UXV4,P24539,Q16891,P56385,O75431,Q5XKP0,Q13505 11
Complex i biogenesis 0.5890369531689091 2.957888681868081 0.0030975396222114 0.9867621035225188 0.1308475828291762 32 O95167,Q8TB37,Q9NX14,O43674,O95139,O43676,Q9BU61,Q9NPL8,Q9Y6M9,O96000,Q86Y39,P03886,O75306 13
Rab geranylgeranylation 0.6481864773327332 2.8681856546558953 0.0041283320618206 0.996870264391396 0.1379755238276228 21 Q15907,P20339,P61019,P61020,Q9H0U4,P61026,Q13636,Q969Q5,P62820 9
Mitophagy 0.7887737545794657 2.865989390065672 0.0041570817795983 0.9969937161763088 0.1379755238276228 11 P21796,Q15388,Q9NS69,Q8N4H5,Q8IWA4 5
Processing of smdt1 0.7385978459085136 2.7449529711629017 0.0060519569763584 0.9997886637186312 0.1580074077123032 13 Q9H300,Q96TA2,Q9H4I9,Q10713,Q8WWC4,Q8IYU8,Q99623,Q9BPX6,P35232,Q9Y4W6 10
Ire1alpha activates chaperones 0.5776646636222764 2.7182241795239177 0.0065633352148926 0.9998968623693456 0.1663507143556417 27 O14653,O95070,Q9Y5M8,Q9NWM8,P43307,O76024,P49840 7
Transport of vitamins nucleosides and related molecules 0.867804327600306 2.596331049990098 0.0094225231994333 0.9999981443420636 0.2035506800456798 7 O00400,P12235,Q8TB61,P12236 4
Pink1 prkn mediated mitophagy 0.8181194044230905 2.528587275519842 0.0114522609430161 0.9999998936542516 0.2220411959622217 8 P21796,Q15388,Q9NS69,Q8N4H5,Q8IWA4 5
Mitochondrial biogenesis 0.5178609841015903 2.4737016293646046 0.013372132360873 0.999999992923654 0.2420876949487933 35 P04179,Q5XKP0,Q13505,Q9BUR5,Q9NVH1,O75964,P17152,Q86X55,P00846,P56385,Q9Y512,Q6UXV4,P24539,Q16539,O75431,Q9NX63,P36542,Q16891,P54646,P06576 20
Translation of sars cov 1 structural proteins 0.8256655209902689 2.405540228552955 0.0161485738997073 0.9999999998607644 0.2624073219620126 7 P27824,P49840,Q10472 3
Sphingolipid de novo biosynthesis 0.6973682135521848 2.3768021370777404 0.0174634528879951 0.9999999999784172 0.2645852274339901 11 O15269,O15270,Q9P0L0,O95292,Q96G23,O95470,Q06136,P51648 8
Synthesis of pa 0.7241701451282784 2.358795843900635 0.0183343392007533 0.99999999999373 0.2645852274339901 10 Q9NUQ2,Q8NF37,Q8N2A8,Q8NAN2,Q9NPH0,O15120,O15228,P43304 8
Sphingolipid metabolism 0.5385740264790185 2.349795736124838 0.0187837158853161 0.9999999999966882 0.2645852274339901 26 P04062,Q9NXE4,O15269,A0FGR8,Q16739,O15270,P07602,Q9P0L0,O95292,Q96G23,Q13510,O95470,P06865,P27544,Q9NZJ7,Q06136,P17900,P51648 18
Transport of inorganic cations anions and amino acids oligopeptides 0.6813612923827113 2.288021476758109 0.0221362704440084 0.999999999999972 0.2938853428471218 11 P30825,Q70HW3,Q9Y6M7,Q9H2J7,Q9UBX3 5
Translation of sars cov 2 structural proteins 0.579434719249864 2.267391344112969 0.023366329795988 0.9999999999999952 0.3054232356330929 18 P27824,P46977,P49840,Q10472 4
Synthesis of very long chain fatty acyl coas 0.7293718527741362 2.235578561619924 0.025379390198434 0.9999999999999998 0.3168323076967289 9 Q9P035,Q9UKU0,Q53GQ0,Q9NZ01 4
Cargo concentration in the er 0.6210596792092984 2.2256746157277743 0.0260359842453725 1.0 0.3168323076967289 15 Q5JRA6,O14653,O75396,P49755,Q15363,Q96PC5,Q9Y6B6,Q9HCU5 8
Peroxisomal lipid metabolism 0.6243202613453683 2.15514613309289 0.0311504006174616 1.0 0.3419185705570201 14 O14975,P33897,Q15067,O43808,Q5T8D3,O15254,P51648 7
Selective autophagy 0.48540227604382 2.0942883174989846 0.0362343043945312 1.0 0.3633857577408384 32 P08670,P21796,O96008,Q15388,Q8IWA4,P54646,Q8N4H5,Q9NS69 8
Post translational modification synthesis of gpi anchored proteins 0.7255770705939865 2.0792874244195505 0.0375909402904961 1.0 0.3690265546827579 8 O43292,Q92643,Q9Y2B2 3
Pi metabolism 0.5675750708877797 2.0759286319332926 0.0379005521528867 1.0 0.3694641237840852 17 P20339,Q9NTJ5,P48739,Q10713,Q9BTU6,P61106,Q8TBX8,Q9C0I1,Q8N9F7 9
N glycan trimming in the er and calnexin calreticulin cycle 0.5774600160545448 2.041390287991115 0.0412120490308653 1.0 0.3804609029736845 16 Q13438,Q9BUN8,O60858,P27824 4
Synthesis of pg 0.9004975124378097 2.0273327058691812 0.0426283988940288 1.0 0.387946164634729 4 O95674,Q8WUK0,Q8N2A8 3
Class a 1 rhodopsin like receptors 0.7439267489744323 2.0223902521860966 0.0431360513044354 1.0 0.387946164634729 7 P07602,Q9NRV9,Q9NZJ7 3
Peptide ligand binding receptors 0.7439267489744323 2.0223902521860966 0.0431360513044354 1.0 0.387946164634729 7 P07602,Q9NRV9,Q9NZJ7 3
Unfolded protein response upr 0.4375774232796491 2.012173594000186 0.0442016410117471 1.0 0.3949813305793305 43 O14653,O95070,Q9Y5M8,Q9NWM8,P43307,O76024,P49840 7
Metabolism of steroid hormones 0.7613291788344632 1.9901503825762483 0.0465743721645213 1.0 0.410915663274321 6 Q53GQ0,O95772,P30536 3
Transport of small molecules 0.4210268411905644 1.9653209570186676 0.0493771015014512 1.0 0.4112333954518794 155 Q8WTV0,Q9UNS2,P40855,P35613,P30519,Q9H4I9,Q9H936,Q9BUN8,Q10713,P53985,Q9UBV2,P12236,Q9BU23,Q8N4V1,Q9Y6M7,Q13616,O75027,Q99797,P09601,P51798,Q8IYU8,Q99623,Q9H2J7,P35610,Q9HD20,P35232,P56589,Q9Y277,P33897,Q15904,Q8TB61,P21796,P20020,P54709,O00400,Q4KMQ2,P05141,Q93050,P30825,Q13546,Q13438,Q9NW15,Q9UL46,P16615,P45880,Q9H300,P49721,P11166,Q96TA2,Q9Y487,P05023,Q8WWC4,Q70HW3,O15118,P12235,Q9C0H2,Q9BPX6,Q8NE86,P28288,P98194,Q9Y6B6,O95202,Q9Y4W6,Q9UBX3 64
Intra golgi traffic 0.5508700643192838 1.961686064946529 0.0497990452039283 1.0 0.4112333954518794 17 O14653,O43752,O95249,Q96JB2,Q8TBA6 5
Gpcr ligand binding 0.6754742468615348 1.9555096917320467 0.0505229405631291 1.0 0.4112333954518794 9 P07602,Q9NRV9,Q9NZJ7 3
Formation of atp by chemiosmotic coupling 0.6486750534279183 1.951181815319733 0.0510354213867827 1.0 0.4112333954518794 10 O75964,P56385,P00846 3
Ras processing 0.7501096153579736 1.938129443262418 0.0526074321153156 1.0 0.421464140050287 6 O60725 1
Depolymerisation of the nuclear lamina 0.6703463959043271 1.928393000311264 0.0538062618204775 1.0 0.4237660077243311 9 Q9Y2U8,P06493,P42167,P50402,P20700,P02545 6
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane 0.8728702655102473 1.9145272576127503 0.0555528197306971 1.0 0.4237660077243311 4 P12235,P12236 2
Metabolism of fat soluble vitamins 0.7996889580093122 1.913277853726723 0.0557124913217019 1.0 0.4237660077243311 5 Q8N0U8,Q6NUM9,P09455,Q9Y5Z9 4
Collagen biosynthesis and modifying enzymes 0.6414700873836972 1.9112648520978208 0.0559705534768089 1.0 0.4237660077243311 10 Q32P28,O75718,O15460,P13674 4
Degradation of cysteine and homocysteine 0.7158303727227313 1.8866716829341972 0.0592044986492952 1.0 0.4296978582308162 7 Q99757,Q9Y6N5,Q9UBX3 3
Sars cov 1 infection 0.5866119761781959 1.8562572030834577 0.0634169060584175 1.0 0.4450265395564214 13 P27824,P49840,Q10472 3
Phase i functionalization of compounds 0.5794007860905142 1.811746298379749 0.070025406250425 1.0 0.4693048861206373 13 P00387,Q16850,O43169,P07099,O75881,P16435 6
O linked glycosylation 0.7652304463471049 1.7605520047541328 0.0783142581206037 1.0 0.4862405212712706 5 Q8N4A0,Q10472 2
O linked glycosylation of mucins 0.7652304463471049 1.7605520047541328 0.0783142581206037 1.0 0.4862405212712706 5 Q8N4A0,Q10472 2
Cell surface interactions at the vascular wall 0.5592941493906596 1.7484066120668156 0.0803936437793972 1.0 0.4936948873501313 14 P54709,P53985,Q08722,P78310,P35613 5
Acyl chain remodelling of pg 0.91858297078931 1.7266133898251408 0.0842371195769602 1.0 0.4956251691242645 2 Q92604 1
Basigin interactions 0.7042484811334839 1.722524917202208 0.0849744730421084 1.0 0.4956251691242645 6 P54709,P35613 2
Stimuli sensing channels 0.5803391813962153 1.7055872395914369 0.0880849568444057 1.0 0.5034684570339475 11 Q4KMQ2,P51790,P51798,Q9C0H2,P27105,Q13546,Q9NW15 7
Attachment of gpi anchor to upar 0.7528954704502712 1.7053721536068178 0.088125038390447 1.0 0.5034684570339475 5 Q9H490,Q92643,O43292 3
Pregnenolone biosynthesis 0.8158415865060213 1.678189713946649 0.0933100691448958 1.0 0.5157872155543061 4 O95772 1
Maturation of sars cov 1 nucleoprotein 0.907085146053442 1.6780012479888342 0.0933468553834848 1.0 0.5157872155543061 2 P49840 1
Diseases associated with n glycosylation of proteins 0.6439756613302593 1.662986247846439 0.0963151883278943 1.0 0.5157872155543061 8 Q9H3H5,O75340,Q13724,Q9BV10,Q9BT22,P15291 6
Er quality control compartment erqc 0.8121310505063593 1.662664775580548 0.096379556905521 1.0 0.5157872155543061 4 Q13438,O60858 2
Response to elevated platelet cytosolic ca2 0.4322544650595516 1.641752011484281 0.1006414079130353 1.0 0.5157872155543061 33 P07602,O94919,Q6UXV4,Q8NBM8,Q96JJ7,Q92520,Q9NZJ7 7
Sars cov 2 infection 0.462696546513043 1.6363182096080422 0.1017730069683455 1.0 0.5177794588097581 24 P27824,P46977,P49840,Q10472 4
Abc transporters in lipid homeostasis 0.8047263681592017 1.6316349676783204 0.1027564073040978 1.0 0.5189943180504073 4 P40855,P33897,P56589 3
Maturation of sars cov 2 spike protein 0.5655211440743169 1.617019617612865 0.1058740463637861 1.0 0.5289907549502435 11 Q13724,P04844,P27824,P46977,Q9H0U3,Q16706,P04843 7
Synthesis of pe 0.7984117444777397 1.6051238600930149 0.1084665493337291 1.0 0.5361786162099943 4 Q9HBU6,Q9C0D9 2
Rac2 gtpase cycle 0.4224171750052931 1.6021734198431583 0.1091172660609214 1.0 0.5374892893601572 35 Q14739,Q8TAA9,Q9Y2U8,Q9Y512,Q86XL3,Q13153,Q13177,Q6IAA8,Q86Y07,P42167,P50402,Q68EM7,Q9UH62,O15173,Q13505,Q9Y6W5 16
Collagen formation 0.561538433064808 1.5930874575105194 0.111140572652636 1.0 0.5455280221048401 11 Q32P28,O75718,O15460,P13674 4
Synthesis of bile acids and bile salts via 7alpha hydroxycholesterol 0.7260260314924285 1.5843179432436565 0.1131213845595866 1.0 0.5460410315832053 5 O14975,O75881,O14734 3
Incretin synthesis secretion and inactivation 0.7883036750890069 1.562597141844695 0.1181473809911066 1.0 0.5505423021399632 4 P67812 1
Synthesis secretion and inactivation of glucagon like peptide 1 glp 1 0.7883036750890069 1.562597141844695 0.1181473809911066 1.0 0.5505423021399632 4 P67812 1
Metabolism of lipids 0.4091058660357858 1.5420643118903576 0.1230579662606186 1.0 0.5505423021399632 198 O14975,Q15125,Q6IAN0,Q86X55,Q9UKU0,Q96SU4,Q16836,P51648,Q14739,O15269,O95864,P33897,Q16739,Q15165,O95674,Q9HBU6,Q9C0I1,Q8NBQ5,Q709F0,Q9NUQ2,O14734,Q99829,Q9NZJ7,O75881,O95772,Q10713,Q9NZ01,Q9BTU6,Q8NAN2,O15120,Q8N9F7,O75192,O00767,Q16850,Q9BVG9,Q53GQ0,Q96G23,Q5T8D3,Q9H2C2,P33121,Q15738,Q9NXE4,Q15800,P07602,Q9NPH0,P30084,P37268,P50416,P50897,P17900,P38435,P23786,Q9P0L0,Q8N2A8,O95470,O14735,P48651,Q92604,Q6P1A2,Q96N66,Q9C0D9,Q8NF37,Q8WUK0,O75845,Q8TBX8,Q9BZF1,Q9NP80,P51659,P43304,P09960,Q9H7Z7,Q9UG56,Q14534,O94830,P30536,Q8IV08,Q9NQZ5,Q9NTJ5,Q13510,O15254,Q9P035,Q9UMR5,Q15067,O43808,O15228,P54646,Q9Y6B6,Q15392,Q53H12,Q6Y1H2,P20339,P53007,P35610,Q06136,P04062,A0FGR8,P48739,O60244 98
Bile acid and bile salt metabolism 0.6442129319275361 1.5318535243102789 0.1255585844435283 1.0 0.5505423021399632 7 O14975,O75881,Q96SU4,O14734 4
Synthesis of bile acids and bile salts 0.6442129319275361 1.5318535243102789 0.1255585844435283 1.0 0.5505423021399632 7 O14975,O75881,Q96SU4,O14734 4
Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps 0.4717005684128556 1.4936354844644812 0.1352709194950565 1.0 0.5505423021399632 18 Q5JRA6,Q07065,Q15293,O76024,Q02818 5
Calnexin calreticulin cycle 0.5885992402022995 1.4855935992035856 0.1373866491240825 1.0 0.5505423021399632 9 Q13438,P27824,O60858 3
Vitamin d calciferol metabolism 0.8610938471100005 1.482970696122089 0.1380821966030518 1.0 0.5505423021399632 2 P38435 1
Cytochrome p450 arranged by substrate type 0.7647958134289058 1.4633152824164923 0.1433811278919914 1.0 0.5505423021399632 4 P16435,Q16850 2
Akt phosphorylates targets in the cytosol 0.6965489309489037 1.4503191331136769 0.1469695459866429 1.0 0.5505423021399632 5 P49841,P49840 2
Sulfur amino acid metabolism 0.5259147866998231 1.423466239548102 0.1546010421835233 1.0 0.5612339916766446 12 Q99757,Q13126,Q9Y6N5,Q9UBX3 4
Synthesis secretion and deacylation of ghrelin 0.8816406038659957 1.3996127949605688 0.1616293003564153 1.0 0.5704082144223872 3 P67812 1
Synthesis secretion and inactivation of glucose dependent insulinotropic polypeptide gip 0.8816406038659957 1.3996127949605688 0.1616293003564153 1.0 0.5704082144223872 3 P67812 1
Initiation of nuclear envelope ne reformation 0.4548123793500059 1.3939550750289589 0.1633311713108709 1.0 0.5735104604719247 19 Q14739,Q8IXJ6,P06493,Q86XL3,Q86Y07,P42167,P50402,P02545 8
Organelle biogenesis and maintenance 0.3411657637018546 1.3912073767578017 0.1641625509655466 1.0 0.5735403409673484 95 Q9H6D7,Q10713,O94927,Q5XKP0,Q13505,Q9BUR5,O75964,Q9NVH1,P41208,P00846,Q96CS2,A6NIH7,P56385,O75935,P06493,Q6UXV4,P24539,O75431,Q16891,P54646 20
Alpha linolenic omega3 and linoleic omega6 acid metabolism 0.5905597298743719 1.381118589736638 0.1672425006428177 1.0 0.5802773383728166 8 O95864,P33897,Q15067,O14734,P33121 5
Pre notch processing in golgi 0.7453358208955186 1.3808026032812215 0.1673396628593058 1.0 0.5802773383728166 4 Q9UBV2,P16615,Q15363 3
Fatty acyl coa biosynthesis 0.4785032514362146 1.365538342106308 0.1720839106667724 1.0 0.5891021657238547 16 Q9P035,Q9UMR5,O00767,Q53GQ0,Q9NZ01,Q9UKU0,Q6Y1H2,P50897 8
Miro gtpase cycle 0.6278756192793828 1.3540350534670968 0.1757251946416713 1.0 0.5920141861328239 6 Q96H55,Q8IWA4,O95140 3
Release of apoptotic factors from the mitochondria 0.8306401491609711 1.3537361552002771 0.1758205689088874 1.0 0.5920141861328239 2 Q9NR28 1
Cholesterol biosynthesis 0.4486034346876991 1.346390086216115 0.1781767464507146 1.0 0.5937384981779449 19 Q14739,Q15125,Q16850,Q15392,Q15800,Q14534,O75845,Q9H2C2,Q15738 9
Maturation of sars cov 2 nucleoprotein 0.6258338188480992 1.3440516171731465 0.1789316960574707 1.0 0.5937384981779449 6 P49840 1
Alpha oxidation of phytanate 0.6728156868340955 1.3417001400586646 0.1796932416090566 1.0 0.5937384981779449 5 P51648,O43808 2
G2 m dna replication checkpoint 0.7360977091291943 1.3415558118461048 0.1797400618587465 1.0 0.5937384981779449 4 P06493 1
Immunoregulatory interactions between a lymphoid and a non lymphoid cell 0.6712843178204069 1.334673901190243 0.1819830990754405 1.0 0.5969045649674449 5 P78310 1
Amino acid transport across the plasma membrane 0.6695471142647671 1.3267010530686216 0.1846075924888466 1.0 0.602676777352347 5 P30825 1
Tp53 regulates metabolic genes 0.3791235165259226 1.323408737709203 0.1856994876044333 1.0 0.6036756822716389 40 Q9P0S2,P09669,O14548,O75880,Q9Y6N1,P54646,Q8N8Q8,P13073 8
Constitutive signaling by akt1 e17k in cancer 0.6215634827527197 1.323154529646137 0.1857839937775216 1.0 0.6036756822716389 6 P49841,P49840 2
Synthesis of pc 0.6683594746650028 1.321249112544831 0.1864183154192298 1.0 0.6036756822716389 5 Q8NF37 1
E3 ubiquitin ligases ubiquitinate target proteins 0.4711585379377848 1.3137182331021346 0.1889410427711688 1.0 0.6068751465967958 16 O75381,Q9BUN8 2
Activation of ampk downstream of nmdars 0.5763490626276719 1.305112674282053 0.1918544836228939 1.0 0.6089180264856358 8 P54646 1
Beta oxidation of pristanoyl coa 0.7225622730090298 1.2839941737543568 0.1991439940080352 1.0 0.6210441334389288 4 O14734,O15254 2
Sulfide oxidation to sulfate 0.8437468497901849 1.252011239793427 0.2105657683760697 1.0 0.6422947070377271 3 Q9UBX3 1
Organic anion transporters 0.7992541951522463 1.2210208151432191 0.2220781387802068 1.0 0.6643281662223356 2 Q9UBX3 1
Proton coupled monocarboxylate transport 0.7977004350528307 1.214473929900188 0.2245667991939652 1.0 0.6674757315061569 2 P35613 1
Defects in cobalamin b12 metabolism 0.7056785931078428 1.2121508862336692 0.2254546278627269 1.0 0.6684847267612852 4 Q96EY8 1
Peptide hormone metabolism 0.4918288368607751 1.208754435149631 0.2267572016411463 1.0 0.669702413321521 12 Q15005,P67812 2
Integrin cell surface interactions 0.7040044966668458 1.2050276358483802 0.2281926334196593 1.0 0.6710981666392513 4 Q08722 1
Ubiquinol biosynthesis 0.828464219078387 1.192618854666509 0.2330186782053833 1.0 0.6721639088746367 3 O75208 1
Metabolism of porphyrins 0.5333494199206071 1.1768567334512896 0.2392526937520456 1.0 0.6721639088746367 9 P09601,P36551,P30519,Q7KZN9 4
Aflatoxin activation and detoxification 0.6969646225226317 1.1750788424569694 0.2399631743821313 1.0 0.6721639088746367 4 Q99735,P10620 2
Wax and plasmalogen biosynthesis 0.6955845771144238 1.169209389640575 0.2423192790295816 1.0 0.6721639088746367 4 Q8WVX9,Q6IAN0,O15228 3
Ion channel transport 0.3859624963987785 1.1505232413280402 0.2499284273764219 1.0 0.6851340408954307 30 P54709,Q4KMQ2,Q15904,P98194,Q9Y487,P05023,P51798,Q93050,Q9C0H2,Q13546,Q9NW15,Q9HD20,P16615 13
Unwinding of dna 0.4874868183993712 1.139800405015047 0.2543694649666044 1.0 0.6952765375753853 11 P49736,P33991,Q9Y248,P33993,Q14566 5
Interleukin 4 and interleukin 13 signaling 0.4788958704496642 1.126621300757931 0.2599026292208299 1.0 0.6994290832699556 12 P09601,Q07820 2
Regulation of gene expression in beta cells 0.7756370416407745 1.1218552518826377 0.2619239894787268 1.0 0.7015469823922286 2 P31751 1
Suppression of apoptosis 0.6843917793168438 1.1216333982550752 0.2620183451436491 1.0 0.7015469823922286 4 P49840 1
Cardiac conduction 0.4974732395804483 1.0811248636287187 0.2796415747805181 1.0 0.7116202139691328 10 P54709,P20020,P05023,Q12797,P16615 5
Ion homeostasis 0.4974732395804483 1.0811248636287187 0.2796415747805181 1.0 0.7116202139691328 10 P54709,P20020,P05023,Q12797,P16615 5
Fatty acid metabolism 0.3392907462440828 1.0808869569903323 0.2797474011872918 1.0 0.7116202139691328 62 O14975,Q9NZ01,Q6Y1H2,Q9H7Z7,O00767,Q53GQ0,Q9UKU0,Q5T8D3,P53007,Q16836,P51648,O95864,P33897,Q15165,O15254,P50416,P50897,Q709F0,Q9P035,Q9UMR5,P23786,Q15067,O43808,P54646 24
Ra biosynthesis pathway 0.7991917935965096 1.0793702813450994 0.2804226936597447 1.0 0.7120386793473299 3 Q9HBH5,Q8NBN7 2
Antigen presentation folding assembly and peptide loading of class i mhc 0.4380226982310032 1.077973227328722 0.2810457041197263 1.0 0.712323111896179 16 P51572,Q9NZ08,P27824,Q03518,P10321,Q9Y6B6 6
Ephrin signaling 0.6112702482089334 1.0585940388302808 0.289784702918809 1.0 0.7135324728650535 5 Q13177 1
Extracellular matrix organization 0.3882426702990358 1.04912852806681 0.2941189677404732 1.0 0.7158678939999726 25 Q32P28,O75718,P13674,O15460,Q92542,Q08722,P35613 7
Signaling by pdgfr in disease 0.6091466849314914 1.0488316719454671 0.2942555977489127 1.0 0.7158678939999726 5 Q6UN15,P40763,O43815 3
Acyl chain remodelling of pc 0.6665557132425541 1.0459839352692657 0.2955684494688775 1.0 0.717809091567274 4 Q6P1A2,Q8NF37 2
Heme biosynthesis 0.6076907352873134 1.0421401978634968 0.2973466840777734 1.0 0.719620273618778 5 P36551,Q7KZN9 2
Acyl chain remodelling of ps 0.7551274083281585 1.036512973940258 0.2999628899064186 1.0 0.724693706290377 2 Q6P1A2 1
Cd28 dependent vav1 pathway 0.5625934003951005 1.0330593034794326 0.301576146836078 1.0 0.7265298185007478 6 Q13177 1
Acyl chain remodelling of pe 0.7541951522684942 1.032655266879301 0.3017652545996649 1.0 0.7265298185007478 2 Q6P1A2 1
Linoleic acid la metabolism 0.7864470003108442 1.0303737756571882 0.302834578768925 1.0 0.7278472462135889 3 O95864,P33897 2
Rnd2 gtpase cycle 0.4199930895360447 1.0211881781592238 0.3071652921981949 1.0 0.7342869640130881 17 Q8TAA9,Q9ULK5,Q07065,P51648 4
Synthesis of pips at the golgi membrane 0.5440345261568541 1.0191164493328402 0.3081476857587206 1.0 0.7342869640130881 7 Q9NTJ5,Q10713,Q9BTU6 3
Tp53 regulates transcription of genes involved in g2 cell cycle arrest 0.5425946077413768 1.011681048158794 0.3116905798934855 1.0 0.7376853452827143 7 Q07812,P06493 2
Rhod gtpase cycle 0.3744584860620912 1.0068908520715707 0.3139872285352039 1.0 0.7406060855804979 27 Q14739,Q9Y2U8,Q86Y07,P42167,Q9Y6M7,P50402,Q68EM7,O15173,Q8NHP6,Q8TAA9 10
Slc transporter disorders 0.3612436384046089 1.0046314653199109 0.3150743401922986 1.0 0.7419149159257843 35 Q8NFH4,P11166,Q7Z3B4,O00400,Q9BTX1,Q8NFH5,Q8TEM1,A8CG34,P35613 9
Keratan sulfate biosynthesis 0.7448725916718459 0.9941966685147984 0.3201271297141888 1.0 0.7436080824747371 2 O43505 1
Apoptotic factor mediated response 0.5914011804179736 0.9674036476460344 0.3333422872969451 1.0 0.7494824975676476 5 Q9NR28 1
Visual phototransduction 0.5126841959036172 0.9616149647314792 0.3362430515533303 1.0 0.751862114704903 8 Q8TC12,P49356,Q6NUM9,P09455 4
Insertion of tail anchored proteins into the endoplasmic reticulum membrane 0.4579362931902841 0.9561205193139196 0.3390113491092394 1.0 0.751862114704903 11 Q13190,P09601,Q9P0L0,O43765,P50402,P51648,P46379 7
Synthesis of dolichyl phosphate 0.7638235808384832 0.944058109217056 0.3451399544986093 1.0 0.751862114704903 3 Q86YN1 1
Glycosphingolipid metabolism 0.4283022092906435 0.9419583830151856 0.3462139473146175 1.0 0.751862114704903 15 P04062,Q9NXE4,A0FGR8,Q16739,P07602,Q13510,P06865,Q9NZJ7,P17900 9
Glycosaminoglycan metabolism 0.4367319217392429 0.9393415866127928 0.3475553934532311 1.0 0.751862114704903 14 Q7LGA3,Q9NRB3,Q8TB61,Q9UHD1,Q8NCH0,P54802,O43505,P15291 8
Pre notch expression and processing 0.47322343623494 0.9375097983423156 0.348496385987934 1.0 0.751862114704903 10 Q9UBV2,P15291,Q15363,Q9H488,P16615 5
Pi3k akt signaling in cancer 0.454754259246074 0.93632944354266 0.3491035930169626 1.0 0.751862114704903 11 P49841,P49840,O43815 3
Piwi interacting rna pirna biogenesis 0.4532393044542753 0.926908770668644 0.3539739030405844 1.0 0.7544948330865056 11 Q9Y2W6 1
Sars cov infections 0.3271962433092221 0.906439883822812 0.3647030705301177 1.0 0.7691317402707778 59 P49356,P54709,P05023,P49841,P27824,P46977,P21964,Q99720,P49840,Q10472 10
Metabolism of steroids 0.3329408203860748 0.9051233809188156 0.3654000267777604 1.0 0.7693730408673685 47 O14975,O95772,Q15125,Q15392,O75845,O00767,Q16850,Q14534,Q53GQ0,Q86X55,Q9H2C2,P30536,Q96SU4,Q14739,P04062,Q15800,Q8NBQ5,P38435,O14734,Q9Y6B6 20
Beta oxidation of very long chain fatty acids 0.5333972514535527 0.8894907443385506 0.3737393953138423 1.0 0.7810985263380754 6 O14734,P33897,Q15067 3
Endogenous sterols 0.7480562458453703 0.8845328104914031 0.3764086587646138 1.0 0.7811952139193178 3 Q16850 1
Fceri mediated mapk activation 0.4982426910467996 0.8836022584029419 0.3769109594876771 1.0 0.7811952139193178 8 Q13177 1
Ptk6 regulates proteins involved in rna processing 0.7175264139216967 0.882850105862716 0.3773172642593736 1.0 0.7811952139193178 2 P23246 1
Peroxisomal protein import 0.3729351505319602 0.8827123570025606 0.3773917039643972 1.0 0.7811952139193178 24 O14975,Q15067,Q92968,Q2T9J0,O75381,O15254,O15228 7
Autophagy 0.3260371051788457 0.838003082125508 0.4020289724890655 1.0 0.7991672760475014 50 P08670,P21796,O96008,Q15388,Q8IWA4,Q8N4H5,Q9NS69 7
Activation of ppargc1a pgc 1alpha by phosphorylation 0.7319758145232154 0.8244953000940253 0.4096581851896843 1.0 0.8028252065180334 3 P54646 1
Activation of rac1 0.5578239640842606 0.8146401322750169 0.4152783313307093 1.0 0.8044391614226868 5 Q13177 1
Carboxyterminal post translational modifications of tubulin 0.5023342670401714 0.8043529834021258 0.4211931463440339 1.0 0.8044391614226868 7 Q9BVA1,P68371,Q13509,Q9BUF5,P04350,Q14166 6
Golgi cisternae pericentriolar stack reorganization 0.4277515605873615 0.80082933668012 0.4232304529250736 1.0 0.8044391614226868 12 Q08379,P06493,P61019,Q9H0U4,P62820 5
Generation of second messenger molecules 0.6070458576415925 0.7969881712188193 0.4254579011855965 1.0 0.8044391614226868 4 Q13177 1
Oncogene induced senescence 0.5130678282514081 0.7902428610833229 0.4293859492253664 1.0 0.8045215231453775 6 Q00534,Q9HCE1,P11802,P04637,P28482 5
Muscle contraction 0.349122105079893 0.785752951579322 0.4320122348168846 1.0 0.8067186097766221 28 P08670,P05023,Q13177,P14649,Q13153,P16615 6
Egr2 and sox10 mediated initiation of schwann cell myelination 0.4979419321019749 0.7818747561643092 0.4342881819161546 1.0 0.8085791957352157 7 Q16850 1
Vitamin c ascorbate metabolism 0.7174386073981771 0.7709129326297897 0.4407585409972698 1.0 0.8148771964856687 3 P00387,P11166 2
Asparagine n linked glycosylation 0.3178898716264551 0.762565635410152 0.445722485494729 1.0 0.8205278705343377 125 Q5JRA6,O14653,O43731,O75396,Q9BUN8,Q9UBV2,O95249,Q86YN1,Q9HCU5,P62820,Q9H3H5,Q9BVK6,Q9Y6Y8,Q9BV10,Q96JB2,O60858,Q96PC5,P24390,Q86SQ9,O75935,Q9BT22,Q15363,Q13438,Q12893,P49755,Q13190,Q13509,P27824,P46977,Q9H0U4,Q9Y6B6 31
Regulation of tnfr1 signaling 0.6858297078930815 0.7573711108731299 0.4488275587428445 1.0 0.8206896135179355 2 Q13546 1
Cytoprotection by hmox1 0.309935161563382 0.7567956763385201 0.4491722835632625 1.0 0.8206896135179355 66 Q9P0S2,P09669,P30519,O14548,P49721,P09601,Q8TCT9,Q9Y6N1,Q8N8Q8,P13073 10
Transport of connexons to the plasma membrane 0.5021779713752521 0.7374992462283313 0.4608188014252579 1.0 0.832368517384039 6 Q9BVA1,P68371,Q13509,Q9BUF5,P04350 5
Gap junction assembly 0.5021779713752521 0.7374992462283313 0.4608188014252579 1.0 0.832368517384039 6 Q9BVA1,P68371,Q13509,Q9BUF5,P04350 5
Synthesis of pips at the plasma membrane 0.4552087333653798 0.7362726418499671 0.4615647921256345 1.0 0.832368517384039 9 Q9BTU6,Q8TBX8,P20339 3
Interleukin 15 signaling 0.6796146674953464 0.7333322846350678 0.4633557887302357 1.0 0.832368517384039 2 P40763 1
Signaling by ntrk3 trkc 0.6796146674953265 0.7333322846349907 0.4633557887302828 1.0 0.832368517384039 2 Q07812 1
Beta oxidation of butanoyl coa to acetyl coa 0.7034504196456237 0.7200806600214315 0.4714753344220763 1.0 0.8394174207909465 3 Q16836,P30084 2
Chondroitin sulfate dermatan sulfate metabolism 0.5346444832464434 0.7109125440236547 0.477138432220062 1.0 0.8408902452914883 5 Q8NCH0 1
Gaba receptor activation 0.5839612290774256 0.7029645156736247 0.4820778634048617 1.0 0.8418758403506332 4 Q9Y639 1
Rhoj gtpase cycle 0.3577337552442168 0.7003714903533261 0.4836953359656397 1.0 0.8418758403506332 22 O75323,Q13177,P42167,Q9Y6M7,Q13153 5
Transport of bile salts and organic acids metal ions and amine compounds 0.5828165384283867 0.6983564508489354 0.4849543040183346 1.0 0.8418758403506332 4 P35613,Q9H2J7 2
Tysnd1 cleaves peroxisomal proteins 0.4925698894088691 0.6912897897213219 0.4893834469495783 1.0 0.8461534218438226 6 Q15067 1
Gastrin creb signalling pathway via pkc and mapk 0.5263654542944919 0.6743575181956086 0.5000840442114334 1.0 0.8543102421945321 5 Q15418,P51812 2
Prevention of phagosomal lysosomal fusion 0.6857320484923799 0.6568826475701994 0.5112563765841627 1.0 0.8647107050118253 3 O14964,P20339 2
Ion transport by p type atpases 0.4235607857444302 0.6457595157172141 0.5184351102226579 1.0 0.8705988497473299 10 P98194,P05023,Q9HD20,P16615 4
Regulation of beta cell development 0.6807584706247934 0.639410161296495 0.5225561403604821 1.0 0.874095719597486 3 O00330,P31751 2
Endosomal vacuolar pathway 0.6792042275411903 0.6339758000068305 0.5260966154900335 1.0 0.8761991421661968 3 P10321,Q9UIQ6 2
Fbxw7 mutants and notch1 in cancer 0.6528899937849477 0.632552708129196 0.5270257782766283 1.0 0.8762484124008484 2 Q13616 1
Rhog gtpase cycle 0.3252356285149678 0.630594564533495 0.5283056537690198 1.0 0.8762484124008484 34 Q14739,Q13190,Q9Y2U8,Q86XL3,Q13177,Q6IAA8,Q86Y07,O95202,P42167,P50402,O15173,Q8TAA9 12
Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein 0.3524959701339435 0.6171540566049721 0.5371331162539665 1.0 0.8762484124008484 20 Q9BV10,Q86YN1,Q9BT22,Q86SQ9 4
Ncam signaling for neurite out growth 0.5129082426127489 0.6156301598316449 0.538138641152992 1.0 0.8762484124008484 5 P62993,Q01082,P28482,Q13813 4
Abortive elongation of hiv 1 transcript in the absence of tat 0.3877088150436375 0.6120104142375407 0.5405308673132476 1.0 0.8762484124008484 14 Q8IXH7 1
Rhoh gtpase cycle 0.3468026314914093 0.6114220333907235 0.5409202196586864 1.0 0.8762484124008484 22 O75323,Q9BXS4,Q13177,Q9Y6M7,Q13153 5
Assembly of the hiv virion 0.6457426973275364 0.6063998370126827 0.544249276676636 1.0 0.8762484124008484 2 Q99816 1
Raf independent mapk1 3 activation 0.4602501903469492 0.5914836682023042 0.5541963947726449 1.0 0.8839242269028227 7 P06493 1
Nf kb activation through fadd rip 1 pathway mediated by caspase 8 and 10 0.6603197741922016 0.5690015259952221 0.5693551043502414 1.0 0.8933187948118682 3 Q7Z434 1
Cd28 co stimulation 0.4246437641781117 0.5675670856708067 0.5703289619558378 1.0 0.8933187948118682 9 Q13177 1
Reactions specific to the complex n glycan synthesis pathway 0.6345556246115697 0.5662306972164214 0.5712369647822642 1.0 0.893719785529154 2 Q16706 1
Activation of nmda receptors and postsynaptic events 0.3342417764733963 0.5547540610518173 0.5790628930729635 1.0 0.8943449427715678 24 P52292,Q15418,P07196,P54646 4
Rac3 gtpase cycle 0.3167716410181427 0.548126829328083 0.5836048196155899 1.0 0.894902266114157 34 Q14739,Q9UQB8,Q13177,Q6IAA8,Q86Y07,P42167,P50402,Q68EM7,Q13153,O15173,Q8TAA9,Q9Y6W5 12
Interactions of vpr with host cellular proteins 0.3151179266226985 0.5462398700998239 0.5849010630219196 1.0 0.894902266114157 35 Q8NFH4,Q7Z3B4,Q8NFH5,Q9BTX1,P05141,P12236,A8CG34,P12235 8
Receptor mediated mitophagy 0.6514953702055173 0.5393635305994057 0.5896360400528455 1.0 0.8971261386400402 3 Q96HS1 1
Circadian clock 0.4187135065314106 0.535431485607907 0.5923515229301963 1.0 0.8971261386400402 9 P50416,Q9BWF3,Q86X55,P43490 4
Heme degradation 0.5391215354599157 0.5274966323176159 0.5978487544574187 1.0 0.8980615988293553 4 P30519 1
G alpha i signalling events 0.3407154114712033 0.5255805004707634 0.599179707949367 1.0 0.8990611404520719 20 Q9NRV9,Q9NZJ7 2
Ovarian tumor domain proteases 0.4167196299870893 0.5246823043952522 0.599804060703319 1.0 0.8990611404520719 9 P06493,Q7Z434 2
Sema3a pak dependent axon repulsion 0.4457276425115514 0.5198925991498676 0.6031384339684149 1.0 0.8996031577763552 7 Q13177 1
Purine salvage 0.4900904760269595 0.5184460946086031 0.6041470611329562 1.0 0.8996031577763552 5 P00813 1
Cd209 dc sign signaling 0.488357999006735 0.5112108963867731 0.6092033895556144 1.0 0.9034356649367302 5 Q13177 1
Signaling by retinoic acid 0.3809237936877526 0.5082287564301098 0.6112929262653661 1.0 0.9038697181355664 12 Q8TC12,Q9HBH5,P50416,Q8NBN7 4
Regulation of lipid metabolism by pparalpha 0.3368642714846774 0.4959248755054978 0.6199474148689617 1.0 0.9087346964535568 20 P23786,Q15067,Q86X55,P33121,O60244,P50416,O75192 7
Rsk activation 0.5289329365145015 0.4893751290105096 0.6245761406789463 1.0 0.908994169906178 4 Q15418 1
N glycan antennae elongation in the medial trans golgi 0.6347528753496983 0.4845507632555871 0.6279950470605966 1.0 0.9108050275420896 3 Q16706,P15291 2
Rnd1 gtpase cycle 0.3658847290200766 0.4701797478288166 0.6382266020370311 1.0 0.9171732105190926 14 Q9BXS4,Q9ULK5,P51648 3
Protein ubiquitination 0.3261403301811637 0.4653268507807002 0.6416974091433683 1.0 0.9184047108273669 23 O75381,Q9BUN8 2
Formation of the early elongation complex 0.3508109690001804 0.4600212050686071 0.645500999988442 1.0 0.9219553217048034 16 Q8IXH7 1
Cellular response to chemical stress 0.277291232595083 0.455451071897764 0.6487847600232488 1.0 0.9224889367347684 77 Q9P0S2,P49721,P30519,O14548,P09669,P09601,Q8TCT9,Q99757,O75880,Q9Y6N1,Q8TED1,Q8N8Q8,P13073 13
Diseases of glycosylation 0.3260092355898247 0.4449006760653813 0.6563915340487294 1.0 0.9241797384978222 22 Q9H3H5,Q8NCH0,Q9BV10,Q9BT22,O43505,Q86SQ9 6
Interaction between l1 and ankyrins 0.6219641289360389 0.4440548115995908 0.6570029561343915 1.0 0.9241797384978222 3 Q12955 1
Er to golgi anterograde transport 0.2728898271367503 0.4359279183639313 0.662889028488072 1.0 0.925334643064068 80 Q5JRA6,O14653,O43731,O75396,O95249,Q9HCU5,P62820,Q9BVK6,Q9Y6Y8,Q96JB2,Q96PC5,P24390,O75935,Q15363,Q12893,P49755,Q13509,Q9H0U4,Q9Y6B6 19
Cytosolic sulfonation of small molecules 0.4696385374233731 0.434558840179137 0.6638826765872357 1.0 0.925334643064068 5 Q8TB61 1
Runx2 regulates bone development 0.512748756218898 0.4304885724838578 0.6668402776205513 1.0 0.925334643064068 4 P28482,P46937,Q96PK6 3
Nuclear envelope ne reassembly 0.2892046535251452 0.4211968912704786 0.6736113142275337 1.0 0.9287974006262928 52 Q14739,Q8IXJ6,Q8NFH4,P06493,Q7Z3B4,Q8NFH5,Q86XL3,Q13509,P42167,P50402 10
Gamma carboxylation hypusine formation and arylsulfatase activation 0.380929855185516 0.4051506254590545 0.685366795650614 1.0 0.9346979178690134 10 O60725 1
Interleukin 12 family signaling 0.3064639296087585 0.4010356991210689 0.6883938407859391 1.0 0.9346979178690134 28 Q13177,P51809,P27824,O14979,P04179,P22626,P14174,P52597,Q13126,Q9UL46 10
Intra golgi and retrograde golgi to er traffic 0.2742275818012644 0.3850173671356786 0.7002245484459364 1.0 0.9439626417500304 99 O15260,O14653,O43731,O75396,O95249,P62820,Q9P2W9,Q10472,O43752,Q9BVK6,Q96JB2,P24390,O75935,O60499,P49755,O00461,Q12981,Q13509,Q8TBA6 19
Transport to the golgi and subsequent modification 0.2659200983187515 0.3825164432962987 0.7020783345781987 1.0 0.9446884154459546 83 Q5JRA6,O14653,O43731,O75396,O95249,Q9HCU5,P62820,Q9BVK6,Q9Y6Y8,Q96JB2,Q96PC5,P24390,O75935,Q15363,Q12893,P49755,Q13509,Q9H0U4,Q9Y6B6 19
Nucleotide salvage 0.3928850013474261 0.337730366966039 0.7355663884659303 1.0 0.9710300928228142 8 P00813 1
Free fatty acids regulate insulin secretion 0.5621504039776384 0.3344019730662714 0.7380762507327006 1.0 0.9710300928228142 2 O95573 1
Rora activates gene expression 0.5829983909873281 0.3291739733886538 0.7420241939483401 1.0 0.9710300928228142 3 P50416 1
Nuclear envelope breakdown 0.2810547265943253 0.3248258225122433 0.7453128998552607 1.0 0.9719047543482072 43 Q8NFH4,P06493,Q7Z3B4,Q8NFH5,Q9BTX1,Q9NRG9,Q8TEM1,Q86Y07,A8CG34,P42167,P50402,P02545 12
Apc c cdc20 mediated degradation of cyclin b 0.3633522682732285 0.3112624246955235 0.755601130157717 1.0 0.9765697482957372 10 Q96DE5,P06493,Q9UJX5 3
Negative regulators of ddx58 ifih1 signaling 0.3993629543615048 0.3025901234713021 0.7622022421555621 1.0 0.9765697482957372 7 Q86UT6 1
Tp53 regulates transcription of cell death genes 0.4054138145612946 0.2985484798110699 0.7652845805611177 1.0 0.9765697482957372 6 Q9Y255,Q07812,P04637,P49327,P53611 5
Smooth muscle contraction 0.3379971731800225 0.2965862433688752 0.7667824147617324 1.0 0.9765697482957372 14 Q13177,P14649 2
Platelet activation signaling and aggregation 0.2776307168175891 0.2943051582756345 0.7685247313777801 1.0 0.9765697482957372 54 P07602,O94919,Q6UXV4,Q8NBM8,Q96JJ7,Q92520,Q9NZJ7,Q9Y6I9 8
Signaling by fgfr1 in disease 0.3706010588601707 0.2867035429170125 0.7743393245741748 1.0 0.9765697482957372 9 O94905,P40763,P42224,O95684,P62993,O95429,Q9UBW7,Q16630 8
Fgfr1 mutant receptor activation 0.3706010588601707 0.2867035429170125 0.7743393245741748 1.0 0.9765697482957372 9 O94905,P40763,P42224,O95684,P62993,O95429,Q9UBW7,Q16630 8
Activation of smo 0.542262274704799 0.2811478870136256 0.778596973232276 1.0 0.9765697482957372 2 Q9Y496 1
Tie2 signaling 0.5413300186451346 0.2787780818686288 0.7804151360125189 1.0 0.9765697482957372 2 P62993 1
Downstream signaling of activated fgfr4 0.5413300186451346 0.2787780818686288 0.7804151360125189 1.0 0.9765697482957372 2 P62993 1
Pi 3k cascade fgfr3 0.5413300186451346 0.2787780818686288 0.7804151360125189 1.0 0.9765697482957372 2 P62993 1
Downstream signaling of activated fgfr1 0.5413300186451346 0.2787780818686288 0.7804151360125189 1.0 0.9765697482957372 2 P62993 1
Pi 3k cascade fgfr1 0.5413300186451346 0.2787780818686288 0.7804151360125189 1.0 0.9765697482957372 2 P62993 1
Activated ntrk2 signals through frs2 and frs3 0.5413300186451346 0.2787780818686288 0.7804151360125189 1.0 0.9765697482957372 2 P62993 1
Frs mediated fgfr1 signaling 0.5413300186451346 0.2787780818686288 0.7804151360125189 1.0 0.9765697482957372 2 P62993 1
Pi 3k cascade fgfr4 0.5413300186451346 0.2787780818686288 0.7804151360125189 1.0 0.9765697482957372 2 P62993 1
Pi 3k cascade fgfr2 0.5413300186451346 0.2787780818686288 0.7804151360125189 1.0 0.9765697482957372 2 P62993 1
Stat5 activation 0.5413300186451346 0.2787780818686288 0.7804151360125189 1.0 0.9765697482957372 2 P62993 1
Frs mediated fgfr4 signaling 0.5413300186451346 0.2787780818686288 0.7804151360125189 1.0 0.9765697482957372 2 P62993 1
Frs mediated fgfr2 signaling 0.5413300186451346 0.2787780818686288 0.7804151360125189 1.0 0.9765697482957372 2 P62993 1
Signaling by flt3 itd and tkd mutants 0.5413300186451346 0.2787780818686288 0.7804151360125189 1.0 0.9765697482957372 2 P62993 1
Frs mediated fgfr3 signaling 0.5413300186451346 0.2787780818686288 0.7804151360125189 1.0 0.9765697482957372 2 P62993 1
Stat5 activation downstream of flt3 itd mutants 0.5413300186451346 0.2787780818686288 0.7804151360125189 1.0 0.9765697482957372 2 P62993 1
Downstream signaling of activated fgfr3 0.5413300186451346 0.2787780818686288 0.7804151360125189 1.0 0.9765697482957372 2 P62993 1
Downstream signaling of activated fgfr2 0.5413300186451346 0.2787780818686288 0.7804151360125189 1.0 0.9765697482957372 2 P62993 1
Synthesis of pips at the er membrane 0.5636140967865432 0.2774689829841569 0.7814200191542824 1.0 0.9769502302251746 3 Q9NTJ5 1
Tp53 regulates transcription of cell cycle genes 0.3167239237203954 0.2761441439972829 0.7824373563036295 1.0 0.9773229948985892 17 Q07812,Q92600,Q86X55,P06493 4
Clec7a dectin 1 induces nfat activation 0.5385332504661415 0.2717384247254389 0.7858231539396787 1.0 0.9773229948985892 2 O43865 1
Calcineurin activates nfat 0.5385332504661416 0.2717384247254387 0.7858231539396789 1.0 0.9773229948985892 2 P62942 1
Synthesis of pips at the early endosome membrane 0.4224840698120109 0.2570933728245224 0.7971066933692654 1.0 0.9845230268939658 5 Q9C0I1 1
Transmission across chemical synapses 0.2745042788871813 0.2569842059100522 0.7971909655842344 1.0 0.9845230268939658 42 Q15418,P52292,P07196,P21964,O75915,P54646,Q9Y639 7
Fgfr2 alternative splicing 0.306646493994924 0.253700569601312 0.7997268939745672 1.0 0.9845230268939658 18 P52298,P31483,P09651,Q01085,P52597,P31943,P35269,P52272 8
E2f enabled inhibition of pre replication complex formation 0.4584725448445365 0.251719323237059 0.8012580200463149 1.0 0.9845230268939658 4 Q9Y619 1
Bmal1 clock npas2 activates circadian gene expression 0.5491580768290579 0.2415431378074476 0.8091341868696813 1.0 0.987802638867838 3 P43490 1
Prolactin receptor signaling 0.5470462966176812 0.2364920912522814 0.8130508435236194 1.0 0.9909324660961544 3 Q13616 1
Syndecan interactions 0.4530472636815841 0.2357403978059824 0.8136341202740591 1.0 0.9909324660961544 4 P05556,O14936,Q9Y296 3
Iron uptake and transport 0.3039571449997437 0.2353598258625476 0.8139294646198687 1.0 0.9909324660961544 18 Q15904,P30519,P09601,Q9Y487,Q93050 5
Copii mediated vesicle transport 0.2844592312908517 0.22760525403447 0.8199531350265996 1.0 0.9946464816229176 32 Q13190,O14653,Q08379,O75396,Q9Y6Y8,Q12907,P49755,Q9H0U4,Q15363,Q9Y6B6,Q9HCU5,P62820 12
Tp53 regulates transcription of death receptors and ligands 0.5195773772529664 0.2268406268864548 0.8205476713531961 1.0 0.9946464816229176 2 P49327 1
Regulation of runx1 expression and activity 0.5414982903326157 0.2234674375629602 0.8231717234157361 1.0 0.9958469231560236 3 Q00534,Q9HCE1 2
Ngf stimulated transcription 0.5170913610938603 0.2213232639269744 0.8248407371039872 1.0 0.9958469231560236 2 Q14839 1
Insulin receptor signalling cascade 0.3858120721841876 0.2209775712158075 0.8251098968760453 1.0 0.9958469231560236 6 P27361,Q06124,P62993,P31751,P28482 5
Signaling by flt3 fusion proteins 0.4465174129353156 0.2170257253057426 0.8281882967964698 1.0 0.9971404535588222 4 P62993,Q01082,Q14789 3
Signaling by nodal 0.5124300807955395 0.2112138070509457 0.8327204373126662 1.0 0.9998383200808412 2 P28482 1
Signaling by activin 0.5124300807955395 0.2112138070509457 0.8327204373126662 1.0 0.9998383200808412 2 P28482 1
Beta oxidation of lauroyl coa to decanoyl coa coa 0.4352123500101219 0.1860125732708892 0.8524349013629362 1.0 1.0 4 Q16836,P30084 2
Beta oxidation of hexanoyl coa to butanoyl coa 0.4352123500101219 0.1860125732708892 0.8524349013629362 1.0 1.0 4 Q16836,P30084 2
Signaling by cytosolic fgfr1 fusion mutants 0.3703703703703666 0.1795748946158482 0.8574863154508288 1.0 1.0 7 P40763,P42224,O95684,P62993,Q9UBW7,Q16630 6
Other interleukin signaling 0.4940957116221409 0.1744606411781494 0.8615034601638656 1.0 1.0 2 Q12846 1
G1 s specific transcription 0.3357926750365638 0.1736962652580421 0.8621041728016055 1.0 1.0 10 Q9Y619 1
G alpha s signalling events 0.4296083355005581 0.1713135749109358 0.863977207017627 1.0 1.0 4 P63096 1
Copi mediated anterograde transport 0.2655127767714502 0.1671593601216698 0.8672446603650257 1.0 1.0 58 O75935,O14653,O43731,Q9BVK6,Q13509,O95249,Q96JB2,Q9H0U4,Q15363,Q12893,P49755,P24390,P62820 13
Signaling by type 1 insulin like growth factor 1 receptor igf1r 0.3949848290499074 0.1670505305113317 0.8673302898835895 1.0 1.0 5 O14654,P31751 2
Ddx58 ifih1 mediated induction of interferon alpha beta 0.3183947771764254 0.1659183925400246 0.8682211729600844 1.0 1.0 13 Q86UT6,Q7Z434 2
Runx2 regulates osteoblast differentiation 0.5125893689773144 0.1615386486454722 0.871669173834535 1.0 1.0 3 P28482,P46937 2
Signal attenuation 0.512589368977312 0.1615386486454671 0.871669173834539 1.0 1.0 3 P62993,P28482 2
Interleukin 20 family signaling 0.5119676717438699 0.1603190457023192 0.8726297566199206 1.0 1.0 3 P40763,Q06124 2
Signaling by pdgfra transmembrane juxtamembrane and kinase domain mutants 0.511967671743868 0.1603190457023161 0.872629756619923 1.0 1.0 3 P62993,P40763 2
Interleukin 2 family signaling 0.511967671743868 0.1603190457023161 0.872629756619923 1.0 1.0 3 P62993,P40763 2
Rhoa gtpase cycle 0.2641921840826206 0.1489971581267631 0.8815558754208841 1.0 1.0 43 Q14739,Q13190,P30519,Q15904,P51572,Q8NBN3,Q5T8D3,Q96CS3,Q9P0I2,P42167,O15173,Q96HY6,Q8TAA9 13
Regulation of tp53 activity through methylation 0.5057506994093925 0.1483876178847806 0.8820368713902695 1.0 1.0 3 P04637,O96017 2
Interleukin 23 signaling 0.4726538222498608 0.1375979163508114 0.8905582023759651 1.0 1.0 2 P40763 1
Metabolism of cofactors 0.3585009737631364 0.1330739749192961 0.8941348770728119 1.0 1.0 7 O75208 1
Rac1 gtpase cycle 0.26383970050694 0.1309905883664593 0.8957827526478801 1.0 1.0 41 Q14739,Q9UQB8,Q9Y2I1,Q13177,Q6IAA8,Q86Y07,P42167,P50402,Q68EM7,Q13153,Q8TAA9,Q9Y6W5 12
Dscam interactions 0.411513088622276 0.1270358666651773 0.8989120110133872 1.0 1.0 4 Q13153 1
Rho gtpases activate nadph oxidases 0.3593652769135 0.1258538133343054 0.8998476435005143 1.0 1.0 6 P27361,P28482,Q16539,Q13526,Q99570 5
Activation of atr in response to replication stress 0.283761650678119 0.1037942431269899 0.9173326351132058 1.0 1.0 18 P40937,P33991,P33993,Q14566,Q99638,Q9Y619,P24941 7
Aurka activation by tpx2 0.2698629706077744 0.0990447516858634 0.921102738057184 1.0 1.0 31 P06493,Q9H6D7,P41208,O94927,Q96CS2 5
Creb1 phosphorylation through nmda receptor mediated activation of ras signaling 0.3278230581340597 0.093982189913444 0.9251233044992876 1.0 1.0 9 P07196 1
Arachidonic acid metabolism 0.3273472698773426 0.0920475370521283 0.9266602707722388 1.0 1.0 9 Q15165 1
Anchoring of the basal body to the plasma membrane 0.2684544680211717 0.090663215431189 0.9277602000458935 1.0 1.0 32 P06493,Q9H6D7,P41208,O94927,Q96CS2 5
Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux 0.4678271681691117 0.0860869251930862 0.9313973172219672 1.0 1.0 3 Q9HCE1,Q8NB78 2
Potential therapeutics for sars 0.2654939627133071 0.0810458581371165 0.935405482909458 1.0 1.0 35 P49356,P54709,P05023,P21964,Q99720 5
Heme signaling 0.3897629240182164 0.080512728500128 0.9358294732208304 1.0 1.0 4 P09601 1
Irs mediated signalling 0.385572139303473 0.0724097313020838 0.9422758406664068 1.0 1.0 4 P62993,Q06124,P31751 3
Recruitment of mitotic centrosome proteins and complexes 0.2659807342456053 0.0703510278971273 0.9439142686932298 1.0 1.0 32 Q15154,O75935,P06493,Q9H6D7,O95684,P41208,Q13561,Q9BSJ2,O94927,Q96CS2,Q15691 11
Trna modification in the mitochondrion 0.3418507519592488 0.0698815172623172 0.9442879642483296 1.0 1.0 6 O75648,Q9Y606 2
Growth hormone receptor signaling 0.3405933865313379 0.0660981465594864 0.9472996864576082 1.0 1.0 6 P18031 1
Myoclonic epilepsy of lafora 0.4070851460534623 0.0633787958290999 0.949464871776542 1.0 1.0 2 P13807 1
Neuronal system 0.2562129261754933 0.0588008945132697 0.9531106959767616 1.0 1.0 54 Q15418,P52292,O95197,P07196,P21964,O75915,P54646,Q9Y639 8
Class b 2 secretin family receptors 0.3943443132380479 0.0548057997215408 0.9562931798397004 1.0 1.0 2 Q9Y3E5 1
Platelet homeostasis 0.3069349154791452 0.0465963663320208 0.9628349281335178 1.0 1.0 10 Q16539,P16615 2
Signaling by pdgf 0.3338518979464787 0.0463713158253506 0.9630142985659886 1.0 1.0 6 P40763,Q06124,P42224,P62993,P46108 5
Downstream signal transduction 0.3338518979464787 0.0463713158253506 0.9630142985659886 1.0 1.0 6 P40763,Q06124,P42224,P62993,P46108 5
Dap12 signaling 0.3589185829708026 0.0384780176522902 0.9693065578745002 1.0 1.0 2 P62993 1
Signaling by notch1 pest domain mutants in cancer 0.3280500208100966 0.0301606205675456 0.975938954467491 1.0 1.0 6 Q13616,Q13573,Q92542 3
Interleukin 7 signaling 0.2734617775015674 0.0260113879276019 0.9792482552723514 1.0 1.0 2 P40763 1
G0 and early g1 0.3235262356389865 0.0180225666073274 0.9856208507843957 1.0 1.0 6 P06493 1
Phosphorylation of the apc c 0.2906932667789819 0.0179036651546765 0.9857157051129416 1.0 1.0 11 Q96DE5,P06493,Q9UJX5 3
G alpha z signalling events 0.3944668946223281 0.013604491883833 0.9891455207978352 1.0 1.0 3 P08754,P63096 2
Gaba b receptor activation 0.3944668946223281 0.013604491883833 0.9891455207978352 1.0 1.0 3 P08754,P63096 2
Adp signalling through p2y purinoceptor 12 0.3944668946223281 0.013604491883833 0.9891455207978352 1.0 1.0 3 P08754,P63096 2
Dap12 interactions 0.3901595212655652 0.0110403956037822 0.9911912177538532 1.0 1.0 3 P10321 1
Methionine salvage pathway 0.3855979046259232 0.0084952369368586 0.9932218631364332 1.0 1.0 3 Q13126 1
Map3k8 tpl2 dependent mapk1 3 activation 0.3711532483680547 0.0015156692544057 0.9987906713656484 1.0 1.0 3 Q13616,P63208 2
Trna processing in the mitochondrion 0.3383084577114346 0.0001686643882295 0.9998654252893124 1.0 1.0 4 O15091,Q9BQ52,Q7L0Y3 3