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Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
Protein localization 0.5843486957731245 4.088054930303349 4.350051636903274e-05 0.0583475497240153 0.0404386568118239 71 Q9NS69,O14734,Q8N4H5,Q99595,P09601,O60220,O60830,P12236,Q10713,P50402,Q96B49,P28288,O43808,Q9HAV7,O15254,P62072,P46379,P12235,O43615,Q15388,O14925,Q9Y512,P51648,O75381,Q13190,O43681,Q9Y584,Q3ZCQ8,P06576,Q15067,P21796,Q5JRX3,Q13505,P40855,Q9UJS0,O96008,Q9Y5J9,Q9Y5Y5,Q9NX63,P05067 40
Mitochondrial protein import 0.6586374064415684 3.750959124237894 0.0001761594192661 0.2160999571727619 0.0404386568118239 37 Q13505,Q9NS69,Q8N4H5,O60220,Q99595,Q9Y584,P62072,P12235,O60830,Q9Y5J9,P12236,P21796,O14925,Q5JRX3,Q96B49 15
Sphingolipid metabolism 0.7338449561819846 3.7129877917078007 0.0002048267711163 0.2465552528409338 0.0404386568118239 25 P06280,Q96G23,P07602,O95470,Q9NZJ7,P17900,P04062,P10619,Q13510,P06865,Q06136,P51648 12
Glycosphingolipid metabolism 0.8000590434489057 3.31156648691371 0.0009277519118084 0.7227257721428113 0.0761286292355576 14 P06280,P07602,P17900,Q9NZJ7,P04062,P10619,P06865,Q13510 8
Glycosaminoglycan metabolism 0.75789603717125 3.2302518182932354 0.0012368123093311 0.8191943370351755 0.0813940291188403 16 O43505,Q96L58,P16278,Q7LGA3,P06865,Q8NCH0,Q9NRB3,Q8TB61,P15586,P08236,P54802 11
Phospholipid metabolism 0.54091222080135 3.10663759810039 0.0018922822100309 0.9270230342903204 0.1174467410394331 49 Q8WUK0,Q96N66,P43304,Q9UG56,Q10713,Q8NF37,Q8IV08,Q08AM6,Q9BTU6,Q8NCC3,Q53H12,O14735,Q7L5N7,O95674,P40939,Q96PE3,Q9NUQ2,P61106,Q9NPH0,Q9NTJ5,Q86UL3,Q8NEB9,P48739,Q9NP80,Q9NQZ5,Q9HBU6,Q92604 27
Slc mediated transmembrane transport 0.6789586652688007 3.0259613627390545 0.0024784397113257 0.9675954128602242 0.1317386031173931 20 P05141,P12235,P12236,O00400,Q99808,Q8TB61,Q9UBX3,Q70HW3 8
Mitochondrial calcium ion transport 0.7103799884268353 2.9510796829018897 0.0031666521199917 0.987515370403098 0.1330627952744756 16 Q99623,Q8IYU8,Q9H4I9,O95202,P45880,Q9Y277,Q9UJZ1,Q10713,P21796 9
Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins 0.4968444293724483 2.9117402884137675 0.0035942134054303 0.9930994279649896 0.1330627952744756 61 Q86Y39,Q9Y6N1,O96000,Q8N8Q8,Q9UDW1,P00846,O75880,Q9P0J0,O14949,P24539,O75438,P21912,Q96I36,P13073,P03886,O75964,O43676,O14548,P56385,O75306,Q9NPL8,O95168 22
Transport of small molecules 0.4803880009183197 2.9096412436013614 0.003618438457821 0.9933274365186509 0.1330627952744756 147 Q9BUN8,Q99623,P98194,O15118,Q9H4I9,Q15904,P09601,P20020,Q9Y6B6,P05141,P12236,Q9UJZ1,P35613,Q10713,Q9UBV2,P61916,P28288,P63218,Q9BPX6,P30519,Q9H0U3,Q92530,P49721,Q9C0H2,P12235,P45880,O00231,Q9HD20,O00400,Q96PU5,P27105,P07237,P61289,P53680,Q9UBX3,Q70HW3,Q99797,Q99808,P25787,Q9UNS2,Q9H936,P35610,P28070,P54709,P16615,P10644,Q86WC4,Q93050,O94905,P21796,Q9Y487,Q8WTV0,P28072,Q8IYU8,P40855,O95202,O75027,Q9Y277,P05023,Q8N4V1,Q8TDW0,Q8TB61,P55011,Q9BU23 64
Glycerophospholipid biosynthesis 0.5775029502859994 2.8909969835905365 0.0038402180625167 0.9950944982295756 0.1330627952744756 32 Q8WUK0,Q96N66,P43304,Q9UG56,Q8NF37,Q8IV08,Q8NCC3,Q53H12,O14735,Q7L5N7,O95674,P40939,Q9NUQ2,Q9NPH0,Q86UL3,P48739,Q9NP80,Q9NQZ5,Q9HBU6,Q92604 20
Mitophagy 0.7347699352653518 2.7135108123447114 0.0066574395630336 0.9999020784826854 0.1566610825188676 12 Q96B49,Q9NS69,Q8N4H5 3
Cristae formation 0.6210003227940302 2.6967673826648904 0.0070016161557771 0.9999393424907213 0.1608050878266943 21 Q13505,Q9NVH1,P56385,P56134,P24539,P06576,P17152,O75964,Q16891,Q9BUR5,P00846,Q9NX63,Q9Y512,Q5XKP0 14
Gpcr ligand binding 0.7786409167831546 2.6508693835595944 0.0080284883118602 0.9999854824197127 0.164616869587377 10 P07602,Q9NZJ7,P42892,P04083,P05067,P63218 6
Respiratory electron transport 0.479674164540197 2.5537228131208916 0.0106578063840245 0.9999996293992472 0.1687214637232732 51 Q9P0J0,O75306,P03886,Q9NPL8,P21912,O14949,Q86Y39,Q9Y6N1,O96000,O75438,O95168,O43676,Q8N8Q8,Q9UDW1,O75880,Q96I36,P13073 17
Cargo concentration in the er 0.6556826474807004 2.5475221908173498 0.0108490952802735 0.9999997163076456 0.1687214637232732 15 Q96PC5,Q12907,P49755,O14653,Q9Y6B6,Q15363,O75396,Q5JRA6,Q9HCU5,Q13190 10
Pink1 prkn mediated mitophagy 0.7952776239193601 2.5385757118456507 0.0111304716643836 0.999999808534578 0.1690363938481119 9 Q96B49,Q9NS69,Q8N4H5 3
Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps 0.6286774574332701 2.519969030512148 0.0117365159999276 0.9999999179386602 0.1725517565095745 17 O43852,Q07065,O76024,P07237,Q5JRA6,Q02818,P05067 7
Peptide ligand binding receptors 0.8269839765727292 2.4763332886398306 0.0132739600464932 0.9999999904569612 0.1784311430902361 7 P07602,Q9NZJ7,P42892,P04083,P05067 5
Class a 1 rhodopsin like receptors 0.8269839765727292 2.4763332886398306 0.0132739600464932 0.9999999904569612 0.1784311430902361 7 P07602,Q9NZJ7,P42892,P04083,P05067 5
G alpha q signalling events 0.6900742479162625 2.464465810761928 0.0137217653781507 0.999999994903891 0.180604569072422 12 P51812,Q8NCG7,Q05655,P04083,P05067,P63218 6
Transport of vitamins nucleosides and related molecules 0.8082064628950179 2.4248969630231305 0.0153127321164583 0.9999999994526292 0.1959462572680132 8 P12235,P12236,O00400,Q8TB61,Q99808 5
Ras processing 0.8809716448116166 2.381088606489777 0.0172615593809171 0.9999999999645808 0.2056506471071331 5 O60725,P49356 2
Heparan sulfate heparin hs gag metabolism 0.8731466227347584 2.3477147156485585 0.0188889826319451 0.999999999996415 0.2189470716136645 5 P08236,Q7LGA3,P16278,P54802 4
Organelle biogenesis and maintenance 0.4020583883486007 2.333028247364234 0.019646662814174 0.9999999999987674 0.2207454309690124 91 Q13409,Q92845,O75935,Q15154,Q10713,P00846,P41208,Q92973,Q96RR1,P24539,P17152,P04350,Q9BUR5,Q9Y512,O95684,O43924,A6NIH7,Q9NVH1,P06576,O75964,P56385,Q13505,O94927,P56134,O43805,Q96CS2,Q16891,Q9H6D7,Q9NX63,Q5XKP0 30
Insertion of tail anchored proteins into the endoplasmic reticulum membrane 0.7096927864572864 2.293293352856806 0.0218311216692557 0.9999999999999436 0.2297047928180156 10 P09601,P46379,P50402,P51648,P05067,Q13190 6
Processing of smdt1 0.6849425902709492 2.2914056044160565 0.021939965739492 0.9999999999999516 0.2297047928180156 11 Q9BPX6,Q99623,Q8IYU8,Q9H4I9,Q9UJZ1,Q10713 6
Cholesterol biosynthesis 0.5995080957875276 2.2600633181355767 0.0238173213500738 0.9999999999999966 0.2336418035188761 16 Q16850,Q14534,Q9BWD1,Q15800,Q9H2C2,P14324,Q14739,Q15392 8
Ion channel transport 0.5149181219928743 2.259737456407572 0.0238375501419403 0.9999999999999968 0.2336418035188761 28 P98194,Q15904,P20020,Q9C0H2,P54709,P16615,Q9HD20,Q93050,Q86WC4,Q96PU5,P27105,P51790,P05023,Q9Y487 14
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane 0.8495582553151277 2.2463367763006965 0.0246824446369713 0.999999999999999 0.2366388434178515 5 P12236,P12235,Q99808 3
Diseases of glycosylation 0.5603907197116863 2.224868228288659 0.0260900854593075 1.0 0.2449770936571038 20 O43505,P16278,Q86SQ9,P10619,Q9BV10,P06865,Q8NCH0,Q9BT22 8
Ire1alpha activates chaperones 0.5126548043638779 2.1898785830632734 0.0285330436022241 1.0 0.2537038128466787 26 Q9Y5M8,P43307,O43731,O76024,O14653,O43909,O95070,O14773,Q9NWM8 9
Keratan sulfate keratin metabolism 0.78477676223988 2.182736355616873 0.0290552309776401 1.0 0.2540749434576787 6 O43505,P15586,P16278,P06865 4
Sphingolipid de novo biosynthesis 0.6633233645447292 2.1710033181828026 0.0299309215522209 1.0 0.2569225688519839 11 O95470,Q06136,Q96G23,P51648 4
Class i peroxisomal membrane protein import 0.7128811105358535 2.128375740629424 0.0333059428704671 1.0 0.2803350238594569 9 O75381,Q8TB36,P40855,Q9Y5Y5,P51648,P28288,O43808 7
Mitochondrial biogenesis 0.4798935476046322 2.1168784226858945 0.0342701673750802 1.0 0.2836010258225205 33 Q13505,Q9NVH1,P56385,P56134,Q5XKP0,P24539,Q96RR1,P17152,P06576,O75431,O75964,Q16891,Q9BUR5,P00846,Q9NX63,Q9Y512,Q04837,P36542 18
Chondroitin sulfate dermatan sulfate metabolism 0.8145607446144901 2.093792739116455 0.0362784472612562 1.0 0.2931977433629016 5 Q96L58,P06865,Q8NCH0 3
The citric acid tca cycle and respiratory electron transport 0.3809816325040039 2.0276211446931653 0.0425989292613702 1.0 0.3199550013000741 94 Q86Y39,Q9Y6N1,O96000,P35613,Q9UDW1,Q8N8Q8,P00846,O75880,Q9P0J0,O14949,P24539,O75438,Q96I36,P13073,P03886,O75964,O43676,P21796,P56385,O43708,O75306,Q9NPL8,Q13423 23
Intra golgi traffic 0.5789078049212847 2.0049836459361288 0.0449647954151282 1.0 0.3317455783254596 14 O00461,O14653,Q8TBA6,O43752,O95721,O95249,Q13190 7
Phase i functionalization of compounds 0.6104401584759498 2.0012173837354794 0.0453689683817017 1.0 0.3317455783254596 12 O43169,P00387,P07099,P16435 4
Iron uptake and transport 0.5358197484184533 1.9661702798114016 0.0492789443154237 1.0 0.3516182367210906 18 P09601,Q9Y487,P30519 3
Diseases associated with glycosaminoglycan metabolism 0.7821539951338133 1.9503044310937032 0.0511398448487259 1.0 0.3516182367210906 5 Q96L58,P06865,Q8NCH0 3
Transport of inorganic cations anions and amino acids oligopeptides 0.7078020941395191 1.942920897430069 0.052025716582543 1.0 0.3524487270444829 8 Q8N697,Q9H936,P08195,Q9UBX3,Q70HW3,P55011 6
Recruitment of mitotic centrosome proteins and complexes 0.4643152180076936 1.9195622142614863 0.0549132207365627 1.0 0.3610797899087555 31 O95684,O94927,Q13409,O43805,O75935,Q96CS2,Q9H6D7,Q15154,Q9BSJ2,P41208 10
Synthesis of pips at the late endosome membrane 0.7692126994439614 1.8924188441744805 0.0584351972357946 1.0 0.3726211350740966 5 Q8NEB9 1
Platelet activation signaling and aggregation 0.4171873700821644 1.8845930403322764 0.0594848026610019 1.0 0.3767315888102558 48 O43852,Q92520,P07602,Q9NZJ7,Q9NTK5,Q8NCG7,Q9Y6I9,Q8NBX0,Q9UEU0,O94919,Q96JJ7,Q05655,Q9NUQ9,P05067,P63218 15
Pre notch processing in golgi 0.7671028765660223 1.882950833287465 0.0597070313436964 1.0 0.3767315888102558 5 P16615,P15291,Q9UBV2 3
Interleukin 4 and interleukin 13 signaling 0.5884666447533686 1.868904374681725 0.061636119582678 1.0 0.3785827433922711 12 P09601,P08670,P04083 3
Complex i biogenesis 0.4714995238601558 1.8559966374769628 0.063454037339121 1.0 0.3880242460294923 26 Q9P0J0,O75306,P03886,Q9NPL8,Q86Y39,O96000,O75438,O43676 8
Synthesis of pa 0.6937244781585894 1.8421895105218455 0.0654474342413324 1.0 0.3947224564533397 7 Q86UL3,Q9NUQ2,Q9NPH0,Q8NF37,P43304 5
Response to elevated platelet cytosolic ca2 0.4601131584077924 1.829842346104709 0.0672735166251761 1.0 0.3951712524748005 29 O43852,Q92520,P07602,Q9NZJ7,Q9NTK5,Q9Y6I9,O94919,Q96JJ7,Q9NUQ9,P05067 10
Stimuli sensing channels 0.6551023045666197 1.8284488810089128 0.0674822109870136 1.0 0.3951712524748005 9 Q9C0H2,Q86WC4 2
Phosphorylation of the apc c 0.6232547184742521 1.822229001724217 0.0684202457965557 1.0 0.3981588483857349 10 Q96DE5,Q9UJX2 2
Conversion from apc c cdc20 to apc c cdh1 in late anaphase 0.6883221588435018 1.8155129770690248 0.0694451135239011 1.0 0.3985005132238768 7 Q96DE5,Q9UJX2 2
Mucopolysaccharidoses 0.8748353096179224 1.7925770183925422 0.0730405838611509 1.0 0.4072605468524312 4 P16278,P15586,P08236 3
Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein 0.5061502266366903 1.7919523178104564 0.073140604327581 1.0 0.4072605468524312 19 Q86YN1,Q86SQ9,P10619,Q9BV10,Q9BT22 5
Metabolism of steroid hormones 0.7016264531648376 1.790474744100598 0.0733776238540198 1.0 0.4072605468524312 6 Q14849,Q53GQ0,O95772 3
Synthesis of dolichyl phosphate 0.9562211981566752 1.7865332777332177 0.0740129540640834 1.0 0.4091436100662535 2 Q86YN1 1
Apc c cdc20 mediated degradation of cyclin b 0.6439290119855796 1.7692968155208202 0.0768443545965986 1.0 0.4136261678514749 9 Q96DE5,Q9UJX2 2
Transcriptional regulation by ventx 0.593142282478164 1.7682292990468411 0.0770225779484343 1.0 0.4136261678514749 11 Q9HCE1,Q96DE5,Q9UJX2 3
Aurka activation by tpx2 0.4416975004584172 1.748487390224284 0.080379667217302 1.0 0.415734804469576 32 O95684,O94927,Q13409,O14965,O43805,O75935,Q9H6D7,Q15154,Q96CS2,P41208 10
Keratan sulfate degradation 0.8640352416981014 1.7482803991311706 0.0804154856017387 1.0 0.415734804469576 4 P15586,P06865 2
Miscellaneous transport and binding events 0.6926355365573174 1.7470995965283036 0.0806200633848381 1.0 0.415734804469576 6 Q8TDW0,Q9H0U3,Q8N4V1 3
Anchoring of the basal body to the plasma membrane 0.4410480404574654 1.7152706608483366 0.086295615034728 1.0 0.4307594572053179 31 O95684,O94927,Q13409,O43805,O75935,Q9H6D7,Q15154,Q96CS2,P41208 9
Synthesis of very long chain fatty acyl coas 0.6615286996012111 1.7116440094088576 0.0869622927353717 1.0 0.4307594572053179 8 Q9P035,Q9UKU0,Q53GQ0 3
Tp53 regulates metabolic genes 0.4201760509822201 1.707693011723944 0.0876933195159117 1.0 0.4312888525658008 37 Q9Y6N1,P31751,Q8N8Q8,P62258,O75880,P20674,Q04917,Q9Y2Q5,O43819,P04637,Q9HCE1,P00403,Q15382,Q96I36,P13073,O00483,O14548,P42345,P54646,Q9NQ88,P54619 21
Formation of atp by chemiosmotic coupling 0.5971696372732322 1.675122253004734 0.0939102476728837 1.0 0.4545081401875916 10 P24539,O75964,P00846 3
Diseases of carbohydrate metabolism 0.5739356201706809 1.6548984937314033 0.0979450898675642 1.0 0.4590190758929653 11 P16278,P54802,P10253,O43826,P15586,P08236 6
Signaling by gpcr 0.4026679487658131 1.6480962269680657 0.0993329264460822 1.0 0.4622158395571908 40 Q9NRV9,P51812,P07602,Q9NZJ7,Q8NCG7,P42892,Q05655,P04083,P52292,P05067,P63218 11
Heme degradation 0.9479598275876996 1.6434021774605625 0.1002997499126365 1.0 0.4651485046284018 3 P09601 1
G alpha z signalling events 0.6706722503228951 1.640411334512631 0.1009196702184613 1.0 0.4661012531794593 6 Q05655 1
Rhoa gtpase cycle 0.3941274221215545 1.605616246658163 0.1083582535449301 1.0 0.4862048909061475 42 P30519,Q96HY6,Q8NBN3,O15173,Q14739,P27105,P42167,Q13190 8
Synthesis of pc 0.7056365396446584 1.603544980046378 0.1088143868239437 1.0 0.4866714646947904 5 Q9NQZ5 1
Synthesis of pips at the golgi membrane 0.5815697543985933 1.5861123213171608 0.1127138323255108 1.0 0.4937768166916666 10 Q08AM6,Q10713,Q8NEB9,Q9NTJ5 4
Rac2 gtpase cycle 0.4245175144952093 1.5676645505804117 0.1169594388642913 1.0 0.4958219156762291 31 Q13505,Q9UH62,O15173,Q14739,Q9Y512,Q86XL3,P42167 7
G alpha i signalling events 0.4482500805534581 1.5601825774811875 0.1187167416110117 1.0 0.4992048022230228 24 Q9NRV9,P07602,Q9NZJ7,Q05655,P04083,P52292,P05067,P63218 8
Transport to the golgi and subsequent modification 0.3414508882670501 1.55502121398948 0.1199410170427397 1.0 0.4992048022230228 79 Q13409,P49755,O75935,Q9Y6B6,O75396,Q5JRA6,Q9HCU5,P24390,P04350,Q9Y3B3,P15291,O14579,Q13190,P56962,O43731,P04066,O14653,Q15363,O15155,O95249,Q9H9E3,Q96PC5,Q12907,Q9UJW0,Q9H0U4 25
Plasma lipoprotein remodeling 0.8992758393679958 1.5451575835801223 0.1223081513211741 1.0 0.4992048022230228 2 Q9BU23 1
Purinergic signaling in leishmaniasis infection 0.8143905712046413 1.5429837634502257 0.122834715449215 1.0 0.4992048022230228 4 P09601 1
Inflammasomes 0.8143905712046413 1.5429837634502257 0.122834715449215 1.0 0.4992048022230228 4 P09601 1
The nlrp3 inflammasome 0.8143905712046413 1.5429837634502257 0.122834715449215 1.0 0.4992048022230228 4 P09601 1
Recruitment of numa to mitotic centrosomes 0.4115870782874686 1.5300537163304415 0.1260034333085309 1.0 0.5075108406787767 34 O94927,Q13409,O43805,O75935,Q9H6D7,Q96CS2,P41208 7
Gamma carboxylation hypusine formation and arylsulfatase activation 0.5701496436884268 1.5204862565417756 0.1283888102916421 1.0 0.5113352617378948 10 P38435,O60725,Q9BU89 3
Selective autophagy 0.4114347004498535 1.474223424058242 0.1404214450091647 1.0 0.5316779095963444 32 Q96B49,Q9NS69,Q8N4H5 3
Asparagine n linked glycosylation 0.3558715394101133 1.4685749441599711 0.1419481149910813 1.0 0.534119278860393 118 Q9BUN8,Q86YN1,Q13409,Q86SQ9,P49755,O75935,P27824,O75396,Q9BV10,Q9BT22,Q5JRA6,Q9HCU5,Q9UBV2,P24390,P16278,Q9H0U3,Q9Y3B3,P15291,O14579,Q13190,P56962,O43731,P04066,O14653,Q15363,O15155,P10619,O95249,Q9H9E3,P46977,Q96PC5,P04844,Q12907,Q9UJW0,Q9H0U4 35
Cytochrome p450 arranged by substrate type 0.902192199739819 1.4643862166078827 0.1430884520029041 1.0 0.5359030912412288 3 P16435 1
Biological oxidations 0.3838237022736543 1.456717677666165 0.1451943280103267 1.0 0.5411761310200268 40 O43169,Q16850,P78417,P07099,P00387,P16435,P21964,Q9UJ14,O43708,Q8TB61 10
Metabolism of lipids 0.3863672558370709 1.4564091243743795 0.1452795547094283 1.0 0.5411761310200268 182 Q16850,Q96G23,P07602,Q9NZJ7,P23786,Q96N66,Q99538,Q8WUK0,Q9UG56,Q9H2C2,P14324,Q10713,Q15392,Q06136,P50897,Q8NF37,Q8IV08,O43808,Q9NZ01,Q9NXE4,Q14849,Q9BTU6,Q08AM6,P06280,O15254,P16278,O95470,Q8NCC3,P17900,Q53H12,O95674,O15269,P04062,Q13510,Q8NBQ5,P51648,O95772,Q14534,P50416,Q53GQ0,Q15165,P09960,Q9NUQ2,Q9UKU0,Q9NPH0,O75192,Q15067,P10619,Q9NTJ5,Q9UMR5,P37268,Q9P035,P38435,Q9BWD1,Q8NEB9,Q15800,Q9NP80,Q9NQZ5,Q14739,Q96SU4,P06865,Q9HBU6,Q8IVS2,Q16836 64
Energy dependent regulation of mtor by lkb1 ampk 0.6158151183136645 1.4508802404290833 0.1468132109904267 1.0 0.5439567227580959 7 P54619,P42345,Q15382,P54646,Q9Y2Q5 5
Integrin cell surface interactions 0.7907993956949794 1.4446389481048587 0.1485593267743461 1.0 0.5489545176527977 4 Q08722 1
Hyaluronan metabolism 0.6691940076276093 1.435048720570731 0.1512732146330511 1.0 0.5535876453617652 5 P06865 1
Hyaluronan uptake and degradation 0.6691940076276093 1.435048720570731 0.1512732146330511 1.0 0.5535876453617652 5 P06865 1
Synthesis of pips at the early endosome membrane 0.6114211211533747 1.4284290847366483 0.1531683926605311 1.0 0.5535876453617652 7 Q08AM6,Q8NEB9 2
Aquaporin mediated transport 0.6655002086967691 1.4178766087907964 0.1562267926848399 1.0 0.554195091327854 5 Q99797,P63218 2
Pregnenolone biosynthesis 0.7839303769404393 1.4159344278621189 0.1567947038416721 1.0 0.554195091327854 4 Q14849 1
Pi metabolism 0.4591898331424969 1.4105571353628064 0.158375238251343 1.0 0.5569327716624837 18 Q08AM6,Q9BTU6,Q8NEB9,Q96PE3,P48739,Q10713,Q9NTJ5 7
Attachment of gpi anchor to upar 0.6589785831960411 1.3875231520002274 0.1652822964127946 1.0 0.5710503341062056 5 Q9H490,Q92643,O43292,Q96S52 4
Intra golgi and retrograde golgi to er traffic 0.3355355525217974 1.3831410759744387 0.1666216129544875 1.0 0.572813604734084 96 Q13409,Q92845,P49755,O75935,Q6NUQ1,O75396,P40616,P24390,Q9P2W9,Q9Y3B3,O14579,Q13190,O15260,O43731,O14653,Q15363,Q12981,O95721,O95249,Q10471,Q9H9E3,O00461,Q8TBA6,O43752,Q10472,Q9UJW0,Q15042,Q7Z6M1,Q9H0U4 29
Autophagy 0.3663140832063759 1.363042650405922 0.1728690693143406 1.0 0.5835144456842721 51 Q676U5,Q9NS69,Q8N4H5,P21796,Q96B49 5
Cytoprotection by hmox1 0.3511018815906774 1.3572997380837353 0.174685990534825 1.0 0.5835144456842721 65 P30519,Q9Y6N1,P49721,P09601,P28070,Q05655,Q8N8Q8,P61289,O75880,Q96I36,P13073,Q8TCT9 12
Hs gag degradation 0.8745472505762246 1.3559412688865249 0.1751178554621961 1.0 0.5835144456842721 3 P16278,P08236 2
Cilium assembly 0.3594150482578063 1.3549902431627912 0.1754206656245736 1.0 0.5835144456842721 58 O94927,O43924,Q13409,A6NIH7,O43805,O75935,Q9H6D7,Q10713,Q96CS2,P41208 10
Initiation of nuclear envelope ne reformation 0.4446740092478055 1.3335274337463217 0.1823587788437333 1.0 0.5835144456842721 19 Q14739,Q86XL3,Q8IXJ6,P42167 4
Unfolded protein response upr 0.3682366309162544 1.3327946411327312 0.1825992048130993 1.0 0.5835144456842721 41 Q9Y5M8,P43307,O43731,O76024,O14653,O43909,O95070,O14773,Q9NWM8 9
Post translational modification synthesis of gpi anchored proteins 0.5876409761252955 1.3316678272331437 0.1829693658067808 1.0 0.5835144456842721 8 Q92643,Q5H8A4,Q9H490,O60762,Q96S52,O43292 6
Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components 0.5628193404335439 1.3298034956155085 0.1835830239140925 1.0 0.5835144456842721 9 Q9UJX3,Q96DE5,Q9UJX2 3
Apc cdc20 mediated degradation of nek2a 0.5628193404335439 1.3298034956155085 0.1835830239140925 1.0 0.5835144456842721 9 Q9UJX3,Q96DE5,Q9UJX2 3
Tyrosine catabolism 0.8469387755101948 1.3227520722085748 0.1859178404996173 1.0 0.5835144456842721 2 O43708 1
Er to golgi anterograde transport 0.3286893489428616 1.2983527193666995 0.1941661581916327 1.0 0.5856293565480265 76 Q13409,P49755,O75935,Q9Y6B6,O75396,Q5JRA6,Q9HCU5,P24390,P04350,Q9Y3B3,O14579,Q13190,P56962,O43731,O14653,Q15363,O15155,O95249,Q9H9E3,Q96PC5,Q12907,Q9UJW0,Q9H0U4 23
Basigin interactions 0.6345832078121802 1.273654555116397 0.2027858687436747 1.0 0.6039872211287899 5 P08195,P54709,P35613 3
Sulfur amino acid metabolism 0.5495799896089244 1.2566499439160388 0.2088804211897463 1.0 0.6181429166685857 9 Q9UBX3 1
Regulation of plk1 activity at g2 m transition 0.3730523928953106 1.246654641957135 0.2125241569144924 1.0 0.6220853206888105 37 O95684,O94927,Q13409,O14965,O43805,O75935,Q9H6D7,Q15154,Q96CS2,P41208 10
Effects of pip2 hydrolysis 0.8463714746269906 1.2454676683338213 0.2129598929564573 1.0 0.6220853206888105 3 Q8NCG7 1
Vitamin c ascorbate metabolism 0.8459192987341007 1.2436968402460684 0.2136111593645959 1.0 0.6220853206888105 3 P78417 1
Rho gtpases activate nadph oxidases 0.5901834608038499 1.2420652806788104 0.2142124772178197 1.0 0.6220853206888105 6 Q8NEB9 1
Rab geranylgeranylation 0.4428122216314381 1.2336087968636105 0.2173487134491221 1.0 0.6249711302735506 17 Q15907,P61019,Q969Q5,P61026,Q9H0U4 5
Formyl peptide receptors bind formyl peptides and many other ligands 0.8426078366809275 1.2307314000975356 0.2184233400304811 1.0 0.6249711302735506 3 P05067,P04083 2
Cellular response to chemical stress 0.3247708467028705 1.2207806198054851 0.2221690935062854 1.0 0.6304675302375493 75 P30519,Q9Y6N1,P49721,P09601,P28070,Q96HE7,P07237,Q8N8Q8,Q05655,P61289,O75880,Q96I36,P13073,Q8TCT9 14
Role of phospholipids in phagocytosis 0.7361009186545058 1.2156217576145636 0.2241290419438633 1.0 0.6347260982918423 4 Q8IV08 1
Metabolism of steroids 0.3550785881215485 1.2013956446704943 0.2295977647887555 1.0 0.6473538437718823 44 Q14849,Q16850,Q14534,O95772,P38435,Q53GQ0,Q9BWD1,Q15800,Q9H2C2,P04062,Q14739,Q15392,Q96SU4 13
Antigen presentation folding assembly and peptide loading of class i mhc 0.4548385865190468 1.1792500723326826 0.2382986128017734 1.0 0.6539506460601505 14 P10321,P51572,P27824,P04439,Q9NZ08,Q03518 6
Keratan sulfate biosynthesis 0.8127057274522719 1.1780464104396002 0.238778104508796 1.0 0.6539506460601505 2 O43505 1
Vitamin d calciferol metabolism 0.8274613105037789 1.171510591086495 0.241393603189421 1.0 0.6554144589543809 3 P38435,P04062 2
Aberrant regulation of mitotic exit in cancer due to rb1 defects 0.5556575868560434 1.1640978524354746 0.2443843588644121 1.0 0.6622336940208188 8 Q96DE5,Q9UJX2 2
N glycan antennae elongation in the medial trans golgi 0.8077682685977624 1.1572843432935744 0.2471562080862368 1.0 0.665230152300119 2 P15291 1
Miro gtpase cycle 0.607578253706752 1.1472667819454008 0.2512713783894169 1.0 0.6716770695051726 5 O95140,Q8IXI1,Q8IWA4,Q8IXI2 4
Nuclear envelope ne reassembly 0.3478942052978755 1.144775622813975 0.252302115870431 1.0 0.6722974593280532 49 Q8IXJ6,Q92973,Q12769,Q7Z3B4,Q8NFH4,Q8NFH5,Q9BTX1,Q14739,Q9BW27,P50402,Q86XL3,Q8N1F7,P42167 13
Synthesis of substrates in n glycan biosythesis 0.4437129339587078 1.1443551082843912 0.2524763975334729 1.0 0.6722974593280532 15 Q86YN1,P10619,Q86SQ9 3
Metabolism of porphyrins 0.5282066724913741 1.1379972148805808 0.2551216453074096 1.0 0.678034834259308 9 P09601,P30519 2
Synthesis of pg 0.8169245966414135 1.1304166937310265 0.2583006831191534 1.0 0.6851661114600193 3 Q8WUK0,Q8IV08 2
Ros and rns production in phagocytes 0.5258654343713086 1.1249683665889727 0.2606024392741857 1.0 0.6870648537855577 9 Q9Y487 1
Noncanonical activation of notch3 0.7995391705069095 1.1227625465201154 0.2615383560431934 1.0 0.6870648537855577 2 Q92542 1
Vitamin b5 pantothenate metabolism 0.712052121630615 1.1149737496108925 0.2648616708651499 1.0 0.6893386612723863 4 Q13057,Q9NRN7 2
Ion transport by p type atpases 0.4991521507129082 1.1053030754226547 0.2690282857674131 1.0 0.6966236673647883 10 P98194,P20020,P16615,Q9HD20,P05023 5
Signaling by insulin receptor 0.4251655410657194 1.1038066149424397 0.2696770347613326 1.0 0.6966236673647883 17 Q8NEB9,Q9Y487 2
Incretin synthesis secretion and inactivation 0.7065238159293575 1.0918840031677717 0.2748840898196034 1.0 0.7048048462536028 4 P67812 1
Synthesis secretion and inactivation of glucagon like peptide 1 glp 1 0.7065238159293575 1.0918840031677717 0.2748840898196034 1.0 0.7048048462536028 4 P67812 1
Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways 0.4952949886042336 1.082498555756383 0.2790310567966672 1.0 0.7101674410552377 10 P09601 1
O linked glycosylation 0.8030951596970617 1.076651957787676 0.2816357827353761 1.0 0.7137898387454359 3 Q10472,O43505 2
O linked glycosylation of mucins 0.8030951596970617 1.076651957787676 0.2816357827353761 1.0 0.7137898387454359 3 Q10472,O43505 2
Copi mediated anterograde transport 0.3388077436627989 1.0758288652698524 0.2820038002568799 1.0 0.7137898387454359 54 Q13409,P24390,O43731,P49755,O75935,O14653,Q15363,O15155,Q9UJW0,Q9Y3B3,O95249,O14579,Q9H0U4,Q13190 14
Acyl chain remodelling of pc 0.7018629335735106 1.072437029506197 0.2835237833696142 1.0 0.7144052545040539 4 Q8NF37,Q9NP80 2
Methylation 0.5557320435143169 1.0694816370362266 0.2848526988903481 1.0 0.7144052545040539 6 P21964 1
Chylomicron assembly 0.7860434496379081 1.066402871307408 0.2862415642878013 1.0 0.7144052545040539 2 P07237 1
Plasma lipoprotein assembly 0.7860434496379081 1.066402871307408 0.2862415642878013 1.0 0.7144052545040539 2 P07237 1
Alpha oxidation of phytanate 0.6995135118101794 1.06264208264155 0.2879442951654987 1.0 0.7157176545300705 4 P51648 1
Metabolism of folate and pterines 0.5332236173912349 1.045988914039233 0.2955661507597575 1.0 0.7241790636619592 8 Q9H2D1 1
Abc transporters in lipid homeostasis 0.7801184990124853 1.041775273060769 0.297515880787178 1.0 0.7241790636619592 2 P40855 1
Synthesis of pe 0.7927899296289127 1.036744673811273 0.2998548660751123 1.0 0.7244745190835756 3 Q9UG56 1
Copii mediated vesicle transport 0.3611828994525264 1.0274211160613411 0.304222212595693 1.0 0.7324653271903271 33 P56962,Q12907,P49755,Q8WVM8,O15498,Q9Y6B6,O00743,O14653,O15027,Q15363,Q9H0U4,O75396,O15155,O43617,P53634,Q9HCU5,Q13190 17
Glycogen storage diseases 0.5800653241242104 1.018620580188804 0.3083831300174084 1.0 0.7386230254489748 5 P46976,P10253,O43826 3
Diseases associated with n glycosylation of proteins 0.5436408692314776 1.0089157240746154 0.3130150534663984 1.0 0.7445556005001078 6 Q9BV10 1
Postmitotic nuclear pore complex npc reformation 0.3856912952935273 1.0028692941043482 0.3159239296219613 1.0 0.7476145046875866 23 Q92973,Q7Z3B4,Q8NFH4,Q8NFH5,Q9BTX1,Q9BW27,Q8N1F7 7
Nr1h2 and nr1h3 mediated signaling 0.5748980622207742 0.9945238709187958 0.3199678898848845 1.0 0.7524311722328386 5 P49327,Q8NB78,Q9HCE1 3
Cardiac conduction 0.4620142731819942 0.9739822213599364 0.3300653667698521 1.0 0.7564682203581021 11 P20020,P05023,P16615,Q9HD47 4
Translation of sars cov 2 structural proteins 0.4132067716322176 0.970346731321034 0.3318736911248106 1.0 0.7580304823057056 16 P04844,Q9H0U3,P27824,Q10472,P46977 5
Insulin receptor recycling 0.4734539848003234 0.9532316504721228 0.3404727133695659 1.0 0.75845910460066 10 Q9Y487 1
Rnd2 gtpase cycle 0.4258356143834306 0.9442404418115976 0.3450467932188772 1.0 0.75845910460066 13 P51648 1
Endosomal vacuolar pathway 0.670153404391755 0.9408261396926229 0.3467939629909498 1.0 0.75845910460066 4 P04439,Q9UIQ6 2
Platelet calcium homeostasis 0.7677251592583709 0.9404080138147544 0.3470083131498578 1.0 0.75845910460066 3 P16615 1
Reduction of cytosolic ca levels 0.7677251592583709 0.9404080138147544 0.3470083131498578 1.0 0.75845910460066 3 P16615 1
Metabolism of fat soluble vitamins 0.5629875002196014 0.9391136808046194 0.3476723809185098 1.0 0.75845910460066 5 Q8N0U8 1
Formation of fibrin clot clotting cascade 0.7544437129690535 0.9360632657028788 0.3492406150168121 1.0 0.75845910460066 2 Q07021 1
Intrinsic pathway of fibrin clot formation 0.7544437129690535 0.9360632657028788 0.3492406150168121 1.0 0.75845910460066 2 Q07021 1
Gaba receptor activation 0.526336689519611 0.9224436983732138 0.3562971850921501 1.0 0.7651259039053652 6 P63218 1
Rhog gtpase cycle 0.3479214948822249 0.9219742111298034 0.3565420275796347 1.0 0.7651259039053652 34 O95202,O15173,Q14739,Q86XL3,P42167,Q13190 6
Copi dependent golgi to er retrograde traffic 0.3271252381940825 0.9128073892471664 0.3613438513655389 1.0 0.7664962489145426 49 O15260,P24390,Q92845,O43731,P49755,Q9P2W9,Q6NUQ1,Q15363,O75396,Q12981,Q9Y3B3,O14579,Q9H0U4 13
Acyl chain remodelling of pg 0.7478604344963744 0.9092678608198492 0.363208751094735 1.0 0.7664962489145426 2 Q8NF37 1
Synthesis of bile acids and bile salts 0.523202814273737 0.9068246855885173 0.3644995135627089 1.0 0.7664962489145426 6 Q96SU4 1
Bile acid and bile salt metabolism 0.523202814273737 0.9068246855885173 0.3644995135627089 1.0 0.7664962489145426 6 Q96SU4 1
Ptk6 regulates proteins involved in rna processing 0.7579848534738152 0.9033151926034222 0.366358635566993 1.0 0.7671327793236127 3 Q07666,O75525 2
Cd28 dependent pi3k akt signaling 0.7439104674127726 0.8932606615538128 0.3717175992716015 1.0 0.7760026015005337 2 P42345 1
Transferrin endocytosis and recycling 0.4468259951834339 0.8803149058041432 0.378688739917512 1.0 0.7819311855994869 11 Q9Y487 1
Metabolism of cofactors 0.5172464977706503 0.8771857085599816 0.3803857772809764 1.0 0.7827739676431957 6 P00374 1
Peroxisomal lipid metabolism 0.4462464453499282 0.8767448176859692 0.380625257783088 1.0 0.7827739676431957 11 Q15067,P51648,O15254,O43808 4
Hur elavl1 binds and stabilizes mrna 0.5163700130348509 0.8728299838599685 0.3827557539232495 1.0 0.7848196616052387 6 Q05655 1
Synthesis secretion and inactivation of glucose dependent insulinotropic polypeptide gip 0.7488153247747573 0.868608035090577 0.385061558069854 1.0 0.7860488526625379 3 P67812 1
Synthesis secretion and deacylation of ghrelin 0.7488153247747573 0.868608035090577 0.385061558069854 1.0 0.7860488526625379 3 P67812 1
Maturation of sars cov 2 spike protein 0.4540349661431631 0.8384433189258902 0.4017817688756546 1.0 0.8079484821871163 10 P04844,P46977,P27824 3
Plasma lipoprotein assembly remodeling and clearance 0.3948249454518816 0.837822375013975 0.4021304703099255 1.0 0.8079484821871163 16 P35610,Q9Y6B6,Q9BU23,P07237,P61916,Q8WTV0,O15118 7
Slc transporter disorders 0.3390534054498194 0.8362410782915148 0.4030192932607861 1.0 0.8079484821871163 34 Q8TEM1,Q99567,Q12769,Q7Z3B4,Q8NFH4,Q8NFH5,Q9BTX1,P35613,P08195,P57740,O00400,P11166,Q9BW27,Q92621,Q8N1F7,Q9NRG9,P52948 17
Myoclonic epilepsy of lafora 0.7244897959183685 0.8154139706045289 0.4148353901143191 1.0 0.816691119836678 2 P46976 1
Diseases of mitotic cell cycle 0.4187380646984474 0.7957061469562101 0.4262028531852455 1.0 0.8237934868559571 12 Q96DE5,Q9UJX2 2
Nr1h2 nr1h3 regulate gene expression linked to lipogenesis 0.716919025674787 0.7854969845709986 0.4321622376098237 1.0 0.8283609048221587 2 P49327 1
Cell surface interactions at the vascular wall 0.4019515220875962 0.7833226282875417 0.4334376784278275 1.0 0.8296549467967558 13 P62993,P53985,P54709,P35613,Q08722,P08195,Q92896 7
Interactions of vpr with host cellular proteins 0.3331403266452739 0.779131601722381 0.4359021962214116 1.0 0.8332183059169996 34 P05141,Q7Z3B4,P12235,Q8NFH4,Q8NFH5,Q9BTX1,P12236,Q9BW27,Q8N1F7 9
Amino acid transport across the plasma membrane 0.7116524028966437 0.7648437671417315 0.4443645822028719 1.0 0.8435602370939134 2 P08195 1
Golgi to er retrograde transport 0.2939936557727191 0.7618623067775339 0.4461421887070462 1.0 0.8451888748608747 73 Q13409,Q92845,P49755,O75935,Q6NUQ1,O75396,P24390,Q9P2W9,Q9Y3B3,O14579,O15260,O43731,Q15363,Q12981,Q10471,Q10472,Q9UJW0,Q15042,Q9H0U4 19
Beta oxidation of pristanoyl coa 0.6239041603030594 0.7525963586154445 0.4516925064806654 1.0 0.8460184599679419 4 O15254 1
Diseases associated with glycosylation precursor biosynthesis 0.475651220583851 0.7439445143573321 0.4569100435196089 1.0 0.8460184599679419 8 P10619,Q86SQ9 2
Potential therapeutics for sars 0.3331320355849005 0.7423386291995507 0.45788219271425 1.0 0.8460184599679419 32 Q99720,P21964,P49356 3
Vasopressin regulates renal water homeostasis via aquaporins 0.6168266668181968 0.7243815951791799 0.4688314958771971 1.0 0.8590844708542801 4 P63218 1
Glucagon signaling in metabolic regulation 0.6168266668181968 0.7243815951791799 0.4688314958771971 1.0 0.8590844708542801 4 P63218 1
Sialic acid metabolism 0.6132404544347521 0.7101605887728831 0.4776045574560719 1.0 0.8643046836324256 4 P10619 1
Regulation of tp53 activity through association with co factors 0.6935483870967756 0.6949456580578559 0.4870893577349406 1.0 0.8721699671153955 2 P31751 1
Tp53 regulates transcription of death receptors and ligands 0.6935483870967754 0.6949456580578541 0.4870893577349418 1.0 0.8721699671153955 2 P49327 1
Tp53 regulates transcription of several additional cell death genes whose specific roles in p53 dependent apoptosis remain uncertain 0.6935483870967755 0.6949456580578535 0.4870893577349422 1.0 0.8721699671153955 2 P53611 1
Sars cov 2 infection 0.3425689189996864 0.6778565834419671 0.4978626303700013 1.0 0.8818299292440129 24 P04844,Q8NEB9,P27824,Q10472,P46977 5
G alpha s signalling events 0.4756097560975414 0.6727052921897895 0.5011348000815228 1.0 0.8845061222383964 6 P04899,Q9UBI6,Q9Y3E5,P63096,P63218 5
Tp53 regulates transcription of cell death genes 0.6937767533750403 0.6660510135187071 0.5053784941404493 1.0 0.8880978732211771 3 P49327,P53611 2
G1 s specific transcription 0.4241570876025189 0.6633657919099364 0.5070963090980942 1.0 0.8880978732211771 10 Q9Y619 1
Recycling of eif2 gdp 0.4719995296908921 0.655292615684444 0.5122793742109759 1.0 0.8880978732211771 6 Q9NR50 1
Senescence associated secretory phenotype sasp 0.3580294279410826 0.6491445008407895 0.5162449803818736 1.0 0.8880978732211771 18 Q9UJX3,P51812,Q96DE5,Q9UJX2 4
Hemostasis 0.2950212556440005 0.6464882730852748 0.517963189297943 1.0 0.8880978732211771 112 O43852,Q92520,P07602,Q9NZJ7,Q8NCG7,Q9NTK5,Q9Y6I9,P16615,Q07021,Q08722,O94919,Q96JJ7,Q05655,P35613,Q9NUQ9,Q9UIJ7,P05067,P63218 18
Signal amplification 0.4693473961766612 0.6425433926773365 0.5205204242498773 1.0 0.8880978732211771 6 P04899,Q9UBI6,P08754,P63096,P63218 5
Fgfr1 mutant receptor activation 0.4559923446513683 0.6425433358263064 0.5205204611498939 1.0 0.8880978732211771 8 O95684,P62993,P42224,O94905,O95429 5
Association of tric cct with target proteins during biosynthesis 0.3518044972827365 0.6223974143260435 0.5336805802304272 1.0 0.8901250164284832 19 P04062,Q99832,Q9Y2T2 3
Mtorc1 mediated signalling 0.4044270919833913 0.62144051724086 0.534309820311399 1.0 0.8901250164284832 11 P62942 1
Activation of ampk downstream of nmdars 0.4645879099579853 0.6197594682534915 0.5354161571310074 1.0 0.8901250164284832 6 P54646,P04350,Q9BUF5 3
Cargo trafficking to the periciliary membrane 0.3475600911957813 0.6113975144160793 0.5409364477696743 1.0 0.8910813986774165 20 O43924,A6NIH7 2
Activation of ppargc1a pgc 1alpha by phosphorylation 0.6711652402896654 0.6112305253721539 0.5410469774888038 1.0 0.8910813986774165 2 P54646 1
Wax and plasmalogen biosynthesis 0.6776424102732974 0.6091267653730542 0.5424404178392663 1.0 0.8910813986774165 3 O00116,Q6IAN0 2
Gastrin creb signalling pathway via pkc and mapk 0.487755550594974 0.5983151238146983 0.5496296871316675 1.0 0.8910813986774165 5 P51812 1
Ripk1 mediated regulated necrosis 0.4126480914051885 0.5968762766563196 0.5505899871636046 1.0 0.8910813986774165 10 Q8WUM4,O75955,Q9UNE7,P49327,O00560 5
Glucagon like peptide 1 glp1 regulates insulin secretion 0.4873520958308006 0.5965568802134056 0.5508032672808323 1.0 0.8910813986774165 5 P63218 1
Adora2b mediated anti inflammatory cytokines production 0.4468997361477685 0.596219150843986 0.551028833597818 1.0 0.8910813986774165 8 P10644,P04899,Q9UBI6,Q9Y3E5,P08754,P63096,P63218 7
Interleukin 12 family signaling 0.3225351891946806 0.591819739494778 0.5539713034738325 1.0 0.8910813986774165 28 P78417,P27824,Q13126,O14979,P07237,P52597 6
Aflatoxin activation and detoxification 0.5822780874745432 0.5898682839974596 0.5552789588232667 1.0 0.8910813986774165 4 Q9UJ14 1
Immunoregulatory interactions between a lymphoid and a non lymphoid cell 0.4855671425641465 0.5887905831617573 0.5560017636381875 1.0 0.8910813986774165 5 P10321,P04439 2
Ca2 pathway 0.4844740916164044 0.584044927158419 0.5591900858112884 1.0 0.8910813986774165 5 P63218 1
Linoleic acid la metabolism 0.6629361421988009 0.5813155778246151 0.5610277835248798 1.0 0.8910813986774165 2 O95864 1
Mastl facilitates mitotic progression 0.4833607907742956 0.5792194424415896 0.5624411136205545 1.0 0.8910813986774165 5 P30153,O43768,P14635,P30154 4
Activation of smo 0.6599736668860913 0.5706702768914768 0.5682231705791547 1.0 0.8946032862182561 2 P48729 1
Apoptotic factor mediated response 0.5728461143253376 0.5542615370020713 0.5793998693327578 1.0 0.9016771014770276 4 Q9NR28 1
Creb phosphorylation 0.6590713342822314 0.5453948716765417 0.585481966775536 1.0 0.9025731758918238 3 P51812 1
Lysosome vesicle biogenesis 0.3545432504631117 0.5212647827142725 0.6021823305398539 1.0 0.9112050397328508 15 P05067 1
Signaling by ptk6 0.374787983542635 0.5182614116589026 0.6042758924474521 1.0 0.9112050397328508 12 Q8IZL8,P18031,Q07666,O75525 4
Free fatty acids regulate insulin secretion 0.644832126398948 0.5173575832610674 0.6049065637436326 1.0 0.9112050397328508 2 O95573 1
Notch3 activation and transmission of signal to the nucleus 0.5621143027378629 0.5144445163723097 0.606941242365699 1.0 0.9112050397328508 4 Q92542 1
Endosomal sorting complex required for transport escrt 0.3862660944205973 0.5132432500157897 0.6077811756047828 1.0 0.9112050397328508 11 Q9BRG1,O14964,Q9NZZ3,O43633,Q9H444,Q92783,Q9NP79,Q8WUX9,Q9H9H4,Q99816 10
Constitutive signaling by akt1 e17k in cancer 0.4676309069009922 0.5119798903143732 0.6086650837670633 1.0 0.9112050397328508 5 P42345 1
Class b 2 secretin family receptors 0.648840497179729 0.5112074635540931 0.6092057930580197 1.0 0.9112050397328508 3 P63218 1
Platelet homeostasis 0.4143002682169187 0.5111753737118997 0.609228261008071 1.0 0.9112050397328508 9 P20020,P16615,P63218 3
Signaling by cytosolic fgfr1 fusion mutants 0.4383651944627549 0.4968562291860313 0.6192904398938106 1.0 0.9119585613274244 6 O95684,P62993,P42224,Q9UBW7,P40763 5
Transport of bile salts and organic acids metal ions and amine compounds 0.6440566348369963 0.4954663782203951 0.6202709494270715 1.0 0.9119585613274244 3 P53985,P35613 2
Sars cov infections 0.2870630346913335 0.4870401953498972 0.6262298462879765 1.0 0.9158197328782895 56 P04844,Q99720,Q8NEB9,P27824,Q10472,P21964,P49356,P62942,P46977 9
Mtor signalling 0.3493212396604496 0.486050621752453 0.6269312751875908 1.0 0.9158763449357828 15 P54619,P31751,P23588,Q9Y2Q5,Q15382,P42345,P54646,P62942 8
Disorders of transmembrane transporters 0.27073933446975 0.480837619186668 0.6306319110842888 1.0 0.9174034748615656 75 Q9BUN8,P35613,P57740,Q9NRG9,Q9UBV2,P20618,Q92530,P49721,O00231,Q9UL46,O00400,P61289,Q9BW27,Q8N1F7,P25787,P28070,Q7Z3B4,Q8NFH4,Q8NFH5,P08195,O94905,P28072,Q12769,Q9BTX1,O75477,P11166 26
Ra biosynthesis pathway 0.5449855435933253 0.4526169950054949 0.6508245588790096 1.0 0.9275052013668176 4 Q8NBN7 1
Abacavir transport and metabolism 0.6250822909809022 0.4508370048569508 0.6521070286543618 1.0 0.9275052013668176 2 P08183 1
Rsk activation 0.5444530619119143 0.4507318278185943 0.6521828401820866 1.0 0.9275052013668176 4 P51812 1
Budding and maturation of hiv virion 0.3861386138613865 0.4471219892086582 0.6547869830670723 1.0 0.9275142553960966 10 O43633,Q9NZZ3,Q9H444,Q8WUM4,Q9NP79,Q8WUX9,Q9H9H4,Q96PU5,Q99816 9
Signaling by pdgfr in disease 0.4510708401976943 0.4433555293109815 0.6575085966629348 1.0 0.9275142553960966 5 P42224,O43815,P62993,P40763 4
Rhod gtpase cycle 0.3066319597866574 0.4385784273421286 0.6609670311399112 1.0 0.9292537507989392 26 O15173,Q14739 2
Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux 0.6192493159497316 0.4165876863488523 0.6769800176075105 1.0 0.935435872624886 3 Q9HCE1 1
Dna damage recognition in gg ner 0.3386628550114984 0.4151857676817905 0.6780059167801342 1.0 0.935435872624886 15 Q9BT78,P41208 2
Regulated necrosis 0.3369635033983492 0.404028571113446 0.68619170933283 1.0 0.9435328893367216 15 O43633,P04637,Q8WUM4,O75955,Q9UNE7,P49327,O00560 7
Signaling by flt3 fusion proteins 0.5286561264822058 0.3959134306417953 0.6921688927260061 1.0 0.9458523597596984 4 Q14789,P62993,Q9UBW7 3
Rhot1 gtpase cycle 0.6069782751810417 0.3932277265329727 0.6941512929687959 1.0 0.9458523597596984 2 Q8IXI2 1
Acyl chain remodelling of ps 0.6050032916392273 0.3871538011705843 0.6986423496118748 1.0 0.9471884212910672 2 Q6P1A2 1
Interleukin 12 signaling 0.3031371490430445 0.3820795077508921 0.7024023912652058 1.0 0.9488955080435136 25 P78417,Q13126,O14979,P07237,P52597 5
Inla mediated entry of listeria monocytogenes into host cells 0.6000658327847284 0.3721587200176567 0.7097746788051329 1.0 0.9541912510784958 2 P35222 1
Translation of sars cov 1 structural proteins 0.4094884644839681 0.3683144168519881 0.7126388038610478 1.0 0.9554584747158148 6 Q10472 1
Activation of bad and translocation to mitochondria 0.3994063324538368 0.3636519577920738 0.7161179225813428 1.0 0.95625499239862 8 Q9Y3B8,P31751,P27348,P31946,P62258,P63104,Q04917 7
Downregulation of erbb2 signaling 0.5177865612648219 0.359529772339899 0.7191988095345196 1.0 0.9584693874413752 4 Q16543,P31751,Q9UNE7 3
Rhoc gtpase cycle 0.2930600552411334 0.3452929220265201 0.7298741672452258 1.0 0.9615972780168052 29 Q14739,P27105,P42167,Q13190 4
Cyclin a b1 b2 associated events during g2 m transition 0.3562231759656609 0.3410571477855253 0.733060560278608 1.0 0.963929300004792 11 P53350,P06493,P24941,O95067,P63151,P30154,P14635,Q99640,O14980,P30153 10
P75 ntr receptor mediated signalling 0.343554652348281 0.3311142109083655 0.7405582177827204 1.0 0.9700961677494973 12 Q9NQC3 1
Regulation of localization of foxo transcription factors 0.3991430454845128 0.3245130311572599 0.7455496581804959 1.0 0.972138699056568 6 Q9Y3B8,P31751,P27348,P31946,P63104 5
Molecules associated with elastic fibres 0.5799868334430498 0.3140982551410052 0.7534464147187998 1.0 0.978551842380893 2 P05556 1
Elastic fibre formation 0.5799868334430498 0.3140982551410052 0.7534464147187998 1.0 0.978551842380893 2 P05556 1
Depolymerisation of the nuclear lamina 0.3737019814668099 0.3047656727794631 0.7605446276507108 1.0 0.9795644691642892 9 P42167 1
Ion homeostasis 0.3725591743724213 0.2992379144400464 0.7647585223147755 1.0 0.9804232633015024 9 P20020,P05023,P16615 3
Rap1 signalling 0.570770243581305 0.2890990011899876 0.7725056179149876 1.0 0.9864417835608558 2 P31946 1
Phenylalanine and tyrosine metabolism 0.4048060405703929 0.2671390019430756 0.7893621391889531 1.0 0.9932733680586372 5 O43708 1
Mitotic g2 g2 m phases 0.2517593813398083 0.2640772805824321 0.7917203701281896 1.0 0.9942690175937162 87 Q13409,O75935,Q15154,P30154,Q9BSJ2,P41208,Q92530,P20618,P49721,P63208,P04350,O00231,P61289,O95684,P25787,P28070,Q99640,P28072,O94927,O14965,O43805,Q9H6D7,Q96CS2 23
Ptk6 regulates cell cycle 0.5602369980250104 0.2618679078139382 0.793423282296164 1.0 0.9942690175937162 2 P11802 1
Tp53 regulates transcription of genes involved in g1 cell cycle arrest 0.5602369980250104 0.2618679078139382 0.793423282296164 1.0 0.9942690175937162 2 P04637 1
Antigen activates b cell receptor bcr leading to generation of second messengers 0.5529953917050686 0.2439998799606896 0.8072309128866311 1.0 1.0 2 P62993 1
Regulation of lipid metabolism by pparalpha 0.2981095850412318 0.2357712815396587 0.8136101539934841 1.0 1.0 19 P50416,P23786,Q15067,O75192,Q06520,P37268 6
Regulation of kit signaling 0.5467412771560255 0.2291405024837284 0.8187597143608647 1.0 1.0 2 P62993 1
Sars cov 1 infection 0.3119827366078744 0.2279606907656856 0.8196768001743187 1.0 1.0 14 Q10472,Q8NEB9 2
Signaling by kit in disease 0.4670619235836686 0.2069196782134776 0.8360725880945168 1.0 1.0 4 P42224,P07947,P62993 3
Signaling by erbb4 0.3680673193400731 0.2020285462062441 0.8398944076474435 1.0 1.0 6 Q92542,Q96J02 2
Transport of connexons to the plasma membrane 0.4627799736495316 0.1955026547165582 0.844999459616917 1.0 1.0 4 P04350,P68371,Q9BUF5 3
Gap junction assembly 0.4627799736495316 0.1955026547165582 0.844999459616917 1.0 1.0 4 P04350,P68371,Q9BUF5 3
Regulation of hmox1 expression and activity 0.2609522026315204 0.193426856114988 0.8466246844286955 1.0 1.0 45 P25787,Q92530,P20618,P63208,P09601,P49721,P28070,O00231,Q05655,P61289,Q8TCT9,P28072 12
Extracellular matrix organization 0.2737419003051191 0.1920191218598496 0.8477272270576202 1.0 1.0 30 P35613,Q08722,P07237,P05067,Q92542,P13674 6
Ca dependent events 0.3598599566743189 0.1910375536820641 0.8484961713542352 1.0 1.0 7 Q05655,P52292 2
Dna damage reversal 0.3818780889620992 0.1906393243985499 0.8488081787571193 1.0 1.0 5 Q8N3C0,Q9C0B1,Q9H1I8,Q8N9N2 4
Laminin interactions 0.5327625946657812 0.1870370181581354 0.8516316087663476 1.0 1.0 3 P05556,P07942 2
Akt phosphorylates targets in the cytosol 0.4594861660079123 0.1868901632583776 0.8517467518979605 1.0 1.0 4 O15111,P31751,Q96B36 3
Pyruvate metabolism 0.2939967995348647 0.1759085908757387 0.860365756055173 1.0 1.0 17 P35613,O43708,P21796 3
Activation of nmda receptors and postsynaptic events 0.2859246560987204 0.1665696542845756 0.8677086724433494 1.0 1.0 20 P51812,P07196,O14936,P04350,P10644,Q15418,Q9BUF5,P54646,P52292,Q14168 10
Beta catenin phosphorylation cascade 0.3572841133816722 0.1632356713121919 0.8703328812136235 1.0 1.0 6 P48729,P49841,P30154,P35222,P30153 5
Signaling by ctnnb1 phospho site mutants 0.3572841133816722 0.1632356713121919 0.8703328812136235 1.0 1.0 6 P48729,P49841,P30154,P35222,P30153 5
Golgi cisternae pericentriolar stack reorganization 0.3127476882430566 0.1618704063049966 0.8714079077871018 1.0 1.0 12 P53350,P61019,Q9H8Y8,P06493,Q08379,P62820,O60763,O95067,P14635,P27361,Q9H0U4 11
Interconversion of nucleotide di and triphosphates 0.2847217246890712 0.1587438793705283 0.873870665745812 1.0 1.0 20 Q9UIJ7 1
Pre notch processing in the endoplasmic reticulum 0.5125082290980928 0.157485267777934 0.8748624176263449 1.0 1.0 2 Q04721 1
Constitutive signaling by overexpressed erbb2 0.5176160684886311 0.1555469134988521 0.8763901723468517 1.0 1.0 3 Q16543,P62993 2
Assembly of the hiv virion 0.5062541145490473 0.1461906794105598 0.8837708632650394 1.0 1.0 2 Q9H9H4 1
Sumoylation of rna binding proteins 0.2672014484680061 0.1400250326970417 0.8886402120017585 1.0 1.0 30 Q8TEM1,P07910,Q99567,Q12769,Q7Z3B4,Q8NFH4,Q8NFH5,P61978,Q9BTX1,P57740,Q9BW27,Q8N1F7,Q9NRG9,P52948 14
Tryptophan catabolism 0.500000000000002 0.135451839427054 0.8922546398125626 1.0 1.0 2 P08195 1
Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects 0.5051037207770844 0.1316950226359088 0.8952255225890027 1.0 1.0 3 P24941,P11802 2
Sumoylation of ubiquitinylation proteins 0.2662707878359414 0.1223738079387438 0.9026029808245208 1.0 1.0 27 Q8TEM1,Q99567,Q12769,Q7Z3B4,Q8NFH4,Q8NFH5,Q9BTX1,P57740,Q9BW27,Q8N1F7,Q9NRG9,P52948 12
Regulation of glucokinase by glucokinase regulatory protein 0.2662707878359414 0.1223738079387438 0.9026029808245208 1.0 1.0 27 Q8TEM1,Q99567,Q12769,Q7Z3B4,Q8NFH4,Q8NFH5,Q9BTX1,P57740,Q9BW27,Q8N1F7,Q9NRG9,P52948 12
Sumoylation of sumoylation proteins 0.2662707878359414 0.1223738079387438 0.9026029808245208 1.0 1.0 27 Q8TEM1,Q99567,Q12769,Q7Z3B4,Q8NFH4,Q8NFH5,Q9BTX1,P57740,Q9BW27,Q8N1F7,Q9NRG9,P52948 12
G beta gamma signalling through pi3kgamma 0.4291657745333102 0.1148488652826848 0.9085649163845436 1.0 1.0 4 P63218 1
G protein mediated events 0.3117125460100373 0.1120338156331319 0.9107965943457308 1.0 1.0 11 Q05655,P52292 2
Trna modification in the nucleus and cytosol 0.3296959557350249 0.1077278695908946 0.9142115614230923 1.0 1.0 9 Q9UBP6 1
N glycan trimming in the er and calnexin calreticulin cycle 0.2885152987611203 0.0973221210475747 0.9224705893300188 1.0 1.0 14 Q9BUN8,P27824 2
Dag and ip3 signaling 0.3359906461097395 0.096310314313151 0.9232741195322538 1.0 1.0 8 Q05655,P52292 2
Phosphorylation of emi1 0.4830424761277535 0.0944635581900833 0.9247409293136968 1.0 1.0 3 P53350,P14635 2
Carboxyterminal post translational modifications of tubulin 0.3479406919275207 0.0938588984301007 0.9252212439509512 1.0 1.0 5 Q9BVA1,P04350,P68371,Q9BUF5 4
Ns1 mediated effects on host pathways 0.2585572996362786 0.0891720320725847 0.9289451919837596 1.0 1.0 33 Q7Z3B4,Q8NFH4,Q8NFH5,Q9BTX1,Q9BW27,Q8N1F7,P52292 7
Interleukin 15 signaling 0.4667544437129713 0.0875020936722857 0.9302724213066214 1.0 1.0 2 P62993 1
Interleukin 9 signaling 0.466754443712971 0.0875020936722851 0.9302724213066218 1.0 1.0 2 P42224 1
Interleukin 21 signaling 0.466754443712971 0.0875020936722851 0.9302724213066218 1.0 1.0 2 P42224 1
Adenylate cyclase inhibitory pathway 0.4751399407309701 0.0826203621132352 0.9341534100033808 1.0 1.0 3 P04899,P63096 2
Interleukin 2 family signaling 0.4669081330260134 0.0711102772291376 0.9433099888332426 1.0 1.0 3 P42224,P62993 2
Signaling by pdgfra transmembrane juxtamembrane and kinase domain mutants 0.4669081330260134 0.0711102772291376 0.9433099888332426 1.0 1.0 3 P42224,P62993 2
Death receptor signalling 0.2717847615616515 0.0639211823500342 0.9490329856920676 1.0 1.0 18 Q8TCT8,Q9NQC3 2
Mitochondrial translation 0.2485572480738874 0.0585811700679761 0.9532857090309694 1.0 1.0 54 O60783,Q15070 2
Alpha linolenic omega3 and linoleic omega6 acid metabolism 0.322631043237199 0.0584403716736473 0.9533978577603346 1.0 1.0 7 Q15067,O95864 2
Cdc42 gtpase cycle 0.2569868616785529 0.0552052507003361 0.9559749458629712 1.0 1.0 26 Q14739,P27105 2
Synthesis of bile acids and bile salts via 7alpha hydroxycholesterol 0.4487981560750684 0.0486882486247162 0.961167741008742 1.0 1.0 3 O14734,P51659 2
Rac3 gtpase cycle 0.2550591042817794 0.0481218139509827 0.9616191613241688 1.0 1.0 30 O15173,Q14739 2
Peptide hormone metabolism 0.2747047181151021 0.0376534276558759 0.9699640089873474 1.0 1.0 15 Q96HE7,P67812 2
Oncogene induced senescence 0.3121292023731086 0.0259772800338572 0.9792754602413454 1.0 1.0 6 Q00534,Q9HCE1,P04637,P11802,P27361 5
The canonical retinoid cycle in rods twilight vision 0.384792626728113 0.0255258976600765 0.979635491869089 1.0 1.0 2 Q8TC12 1
Signaling by fgfr1 in disease 0.3071597812003168 0.0224083388748704 0.9821222285627962 1.0 1.0 9 O95684,O95429,O94905 3
Growth hormone receptor signaling 0.3120263591433293 0.0154435813766339 0.9876782946544524 1.0 1.0 5 P42224,P27361,P18031,P40763 4
Beta oxidation of butanoyl coa to acetyl coa 0.4099206085891694 0.0130576311920747 0.9895818137251616 1.0 1.0 3 Q16836 1
Traf6 mediated irf7 activation 0.2985516787360134 0.0104864741873727 0.9916331574938156 1.0 1.0 2 Q7Z434 1
Traf3 dependent irf activation pathway 0.2985516787360134 0.0104864741873727 0.9916331574938156 1.0 1.0 2 Q7Z434 1
Fbxw7 mutants and notch1 in cancer 0.2840684660961187 0.0099284200785941 0.9920783970497264 1.0 1.0 2 P63208 1
Glycogen breakdown glycogenolysis 0.3027909817597189 0.0031674896642768 0.9974727131264124 1.0 1.0 6 P10253 1
Ticam1 rip1 mediated ikk complex recruitment 0.3941389529140602 0.0028948773424696 0.9976902252891324 1.0 1.0 3 O15111,O14920 2
Irak1 recruits ikk complex 0.3941389529140602 0.0028948773424696 0.9976902252891324 1.0 1.0 3 O15111,O14920 2
Ikk complex recruitment mediated by rip1 0.3941389529140602 0.0028948773424696 0.9976902252891324 1.0 1.0 3 O15111,O14920 2