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interpro_active_site/advanced/idx2term.json

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+{}

interpro_active_site/basic/idx2term.json

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+{}

interpro_active_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:05984ef2f09bd6901e6b08c0432d33fbc72cea4a01811ee3d8dd40ca8abec5dc
+size 75310

interpro_active_site/df_merge.tsv

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+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_active_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3040,
+    "annotations_size": 55,
+    "title": "Average number of proteins per term",
+    "value": 2.6
+}

interpro_active_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C293/C293_val_log2fc"}

interpro_active_site/result.tsv

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+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Histidine acid phosphatase active site [IPR033379]	0.9048716260697712	1.5689387715455432	0.1166622065728513	0.9989111334363204	0.2212559090174766	2	Q9NPH0	1
+Serine carboxypeptidase, serine active site [IPR018202]	0.8337174843595558	1.1959529674396876	0.2317149134628087	0.9999994944871892	0.3861915224380145	3	Q9HB40,P10619	2

interpro_active_site/selections.json

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+{"all_annotations": ["ATP synthase, F0 complex, subunit A, active site [IPR023011]", "ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenosine/AMP deaminase active site [IPR006650]", "Adenylosuccinate synthase,  active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Coenzyme A transferase active site [IPR004164]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glutaredoxin active site [IPR011767]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycoside hydrolase, family 2, active site [IPR023232]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]", "Uracil-DNA glycosylase, active site [IPR018085]"], "available_proteins": ["ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADA", "ADSS", "AKT2", "APEH", "ATP5A1", "ATP5B", "ATP6", "ATP6V1A", "ATP6V1B2", "AURKA", "BLMH", "BUB1", "CAMK2D", "CAMK2G", "CAPN1", "CAPN2", "CDC34", "CDK1", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CHEK1", "CHEK2", "CHUK", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CTSA", "CTSC", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "EPHA7", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLRX", "GLUD1", "GSK3B", "GSR", "GUSB", "HADHB", "HMGCS1", "IKBKB", "LDHA", "LDHB", "LONP1", "MAP2K1", "MAPK1", "MAPK3", "MAPKAPK2", "MDH1", "MDH2", "MTMR2", "NEK9", "NME1", "NME2", "OXCT1", "PAK2", "PBK", "PGAM1", "PIK3R4", "PKM", "PKMYT1", "PKN2", "PLK1", "PREP", "PRKAA2", "PRKCD", "PRPF4B", "PTK7", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "RNASET2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SRPK2", "SUCLG1", "TALDO1", "TIGAR", "TOP1", "TPI1", "TPP2", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "UBE2T", "ULK3", "UMPS", "UNG", "VRK1", "VRK2", "WNK1", "YES1"], "leading_proteins": ["ACP6", "CTSA", "SCPEP1"]}

interpro_binding_site/advanced/idx2term.json

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+{}

interpro_binding_site/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "EF-Hand 1, calcium-binding site [IPR018247]"}

interpro_binding_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:ccde957cacfb8108894bd3b6f8741570625c19aed66b4982d24dea4bdfc6a195
+size 69787

interpro_binding_site/df_merge.tsv

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+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_binding_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3040,
+    "annotations_size": 31,
+    "title": "Average number of proteins per term",
+    "value": 4.548387096774194
+}

interpro_binding_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C293/C293_val_log2fc"}

interpro_binding_site/result.tsv

@@ -0,0 +1,6 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+EF-Hand 1, calcium-binding site [IPR018247]	0.392248662986251	1.5426689738837285	0.1229111134420357	0.9828465352911512	0.2772725117467243	40	P80303,Q14257,P0DP25,Q9Y680,Q6NUK1,O95302,Q02818,Q9NWM8,P41208	9
+Peptidase M16, zinc-binding site [IPR001431]	0.4885120053524056	0.6016144977973463	0.5474307761748078	0.9999999999788048	0.6087463876737773	5	Q10713	1
+Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]	0.6675444371296919	0.5980067233751343	0.5498354469311537	0.9999999999820316	0.6087463876737773	2	O15270	1
+Beta tubulin, autoregulation binding site [IPR013838]	0.4629324546952163	0.492266605027309	0.6225308847600735	0.9999999999999236	0.6553809025492945	5	P07437,P04350,P68371,Q9BUF5	4
+Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]	0.5757077024358063	0.3023579050934096	0.7623792407149717	1.0	0.7623792407149717	2	P34896	1

interpro_binding_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "APOBEC/CMP deaminase, zinc-binding [IPR016192]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Coenzyme A transferase binding site [IPR004163]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "AKT2", "APEX1", "AURKA", "BPNT1", "BUB1", "CALM3", "CALU", "CAMK2D", "CAMK2G", "CAPN1", "CAPN2", "CDK1", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CETN2", "CHEK1", "CHUK", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A2", "CYB5B", "DBT", "DCTD", "DLAT", "DLST", "DST", "EHD1", "EHD4", "EIF2AK2", "EPHA7", "EPS15", "FKBP10", "FKBP14", "FKBP7", "FKBP9", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3B", "HK1", "HK2", "HMBS", "IDE", "ILKAP", "IQGAP1", "IQGAP2", "ITSN2", "LETM1", "LPCAT2", "MACF1", "MAP2K1", "MAPK1", "MAPK3", "MAPKAPK2", "MCCC1", "METAP2", "MICU1", "MYH10", "MYH14", "MYH9", "MYO1B", "MYO1C", "MYO1D", "NFS1", "NRDC", "NUCB1", "NUCB2", "OXCT1", "OXSR1", "PA2G4", "PAK2", "PC", "PCCA", "PDCD6", "PDHX", "PEF1", "PGD", "PKMYT1", "PKN2", "PLCG1", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1G", "PRKAA2", "PRKCD", "PRKCSH", "PSAT1", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "S100A11", "SDF4", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "SRPK2", "STK26", "STK4", "TKT", "TUBB", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "UBE3C", "ULK3", "UQCRC2", "VRK1", "YES1"], "leading_proteins": ["CALM3", "CETN2", "FKBP14", "FKBP7", "FKBP9", "NUCB1", "NUCB2", "PMPCA", "RCN2", "SHMT1", "SLC25A24", "SPTLC2", "TUBB", "TUBB4A", "TUBB4B", "TUBB6"]}

interpro_conserved_site/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "Syntaxin/epimorphin, conserved site [IPR006012]"}

interpro_conserved_site/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Syntaxin/epimorphin, conserved site [IPR006012]", "1": "14-3-3 protein, conserved site [IPR023409]"}

interpro_conserved_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:4e3b6333fceebab9d8eb3854a2e78a12970c90a44e69d7b169d80c6a2fc3c125
+size 97795

interpro_conserved_site/df_merge.tsv

@@ -0,0 +1,2 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+Syntaxin/epimorphin, conserved site [IPR006012]	6	8	2.4084260946829263	0.0160214697670266	2.592233009708738	5.847087378640777	0.9961908981999794	0.2839139128702306	1.4759357288864456	1.4239341993278547	1.138258151200134	0.2914162845337057	0.0011015965796577	0.0607401038440192	0.1180585699575878	0.0382400085743442	1.6468344784532795e-05

interpro_conserved_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3040,
+    "annotations_size": 271,
+    "title": "Average number of proteins per term",
+    "value": 2.5830258302583027
+}

interpro_conserved_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C293/C293_val_log2fc"}

interpro_conserved_site/result.tsv

@@ -0,0 +1,22 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Syntaxin/epimorphin, conserved site [IPR006012]	0.8046786731159765	2.4084260946829263	0.0160214697670266	0.9874367008466088	0.1027728186312747	8	P56962,O15400,O43752,Q9P2W9,Q13277,Q13190	6
+Haem oxygenase conserved site [IPR018207]	0.9888084265964436	1.9236635497818748	0.0543967697252369	0.9999997387088664	0.1842690574442403	2	P09601	1
+Thioredoxin, conserved site [IPR017937]	0.5394092088648637	1.5667348560571512	0.1171766798579851	0.999999999999998	0.3342618972790945	12	P07237,Q96JJ7,Q9H1E5	3
+Tetraspanin, conserved site [IPR018503]	0.8749177090190711	1.4415949256462506	0.1494166807858103	1.0	0.3864806070561967	2	O43657	1
+Polyprenyl synthetase, conserved site [IPR033749]	0.8676761026991445	1.410811594357241	0.1583001748458961	1.0	0.3864806070561967	2	Q5T2R2	1
+Glycoside hydrolase, family 29, conserved site [IPR018526]	0.8077682685977624	1.1572843432935744	0.2471562080862368	1.0	0.5014740542008198	2	Q9BTY2	1
+Intermediate filament protein, conserved site [IPR018039]	0.5447771795255602	1.106847540018514	0.2683598502282822	1.0	0.5232051756249243	8	Q16352,P07196,P08670	3
+3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]	0.7722185648452711	1.0090634346706262	0.3129442127738726	1.0	0.5790380659536397	2	Q16836	1
+Proteasome beta-type subunit, conserved site [IPR016050]	0.5134475574253535	0.9418221015027792	0.3462837276836008	1.0	0.6015569884759989	8	P28070,P49721	2
+Sugar transporter, conserved site [IPR005829]	0.7093482554311825	0.7558509768751153	0.4497385490312877	1.0	0.6457806590376296	2	Q7L0J3	1
+C-type lectin, conserved site [IPR018378]	0.708689927583938	0.7532865433381917	0.4512777433862711	1.0	0.6457806590376296	2	Q9UBG0	1
+Guanylate kinase, conserved site [IPR020590]	0.5202635914332723	0.742924723155322	0.4575272565875456	1.0	0.6457806590376296	5	Q00013,Q5T2T1,Q14168,O14936	4
+EGF-like, conserved site [IPR013032]	0.6445029624753141	0.5162199165978113	0.605700821436691	1.0	0.7495201945632112	2	O94813	1
+EGF-like calcium-binding, conserved site [IPR018097]	0.6445029624753141	0.5162199165978113	0.605700821436691	1.0	0.7495201945632112	2	O94813	1
+Tubulin, conserved site [IPR017975]	0.4629324546952166	0.4922666050273103	0.6225308847600726	1.0	0.7537863163071451	5	P07437,P04350,P68371,Q9BUF5	4
+Actin, conserved site [IPR004001]	0.5868992758393696	0.3335422483937915	0.7387250037752482	1.0	0.8341436500962177	2	P61163	1
+14-3-3 protein, conserved site [IPR023409]	0.3991430454845158	0.3245130311572731	0.7455496581804859	1.0	0.8383566695722476	6	P27348,P31946,P62258,P63104,Q04917	5
+S100/Calbindin-D9k, conserved site [IPR001751]	0.5543120473996068	0.2471960724604582	0.8047564847288204	1.0	0.8846082139390784	2	P31949	1
+RNA polymerase, beta subunit, conserved site [IPR007121]	0.4878209348255453	0.1161215152916007	0.9075562374250016	1.0	0.9569950986076866	2	P30876	1
+Ribosomal protein S5, N-terminal, conserved site [IPR018192]	0.4282422646477968	0.0497229101535463	0.9603431993759924	1.0	0.9820868189845054	2	P82675	1
+D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]	0.2748518762343674	0.00969018452204	0.9922684723767126	1.0	1.0	2	O43175	1

interpro_conserved_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Amyloidogenic glycoprotein,  copper-binding domain conserved site [IPR019744]", "Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Band 7/stomatin-like, conserved site [IPR018080]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific,  conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 14-18kDa subunit, conserved site [IPR020708]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Di-trans-poly-cis-decaprenylcistransferase-like, conserved site [IPR018520]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Endonuclease III-like, conserved site-2 [IPR004036]", "Endonuclease III-like, iron-sulphur cluster loop motif [IPR003651]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Ependymin, conserved site [IPR018224]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "Fibrillarin, conserved site [IPR020813]", "Fork head domain conserved site 2 [IPR030456]", "Fork head domain conserved site1 [IPR018122]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glutathione peroxidase conserved site [IPR029760]", "Glycerate/sugar phosphate transporter, conserved site [IPR021159]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 2, conserved site [IPR023230]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Golgin subfamily A member 2, C-terminal binding motif [IPR043937]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Helix-hairpin-helix motif [IPR000445]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NADH:ubiquinone oxidoreductase, subunit 1, conserved site [IPR018086]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "PTR2 family proton/oligopeptide symporter, conserved site [IPR018456]", "Peptidase M22, conserved site [IPR017860]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosyl pyrophosphate synthetase, conserved site [IPR000842]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase, RluC/RluD, conserved site [IPR006224]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Pyridoxamine 5'-phosphate oxidase, conserved site [IPR019740]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P,  conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S14, conserved site [IPR018271]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "Tyrosine-protein kinase, receptor class V, conserved site [IPR001426]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]"], "available_proteins": ["AAAS", "AAMP", "ABCB1", "ABCB10", "ABCB7", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK3", "AK4", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1M1", "AP2M1", "AP2S1", "AP3M1", "AP3S1", "APEX1", "APP", "ATAD1", "ATAD2", "ATG16L1", "ATP5C1", "ATP5O", "BAG6", "BAZ1A", "BAZ1B", "BAZ2A", "BCS1L", "BDH2", "BLM", "BOP1", "BPNT1", "BRD2", "BRPF1", "BUD31", "CAD", "CALR", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CBR1", "CBX1", "CBX3", "CBX5", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDC40", "CDH2", "CDKAL1", "CETN2", "CHAF1B", "CHD1", "CHD1L", "CHD4", "CHD5", "CLGN", "CMPK1", "CNDP2", "COLEC12", "COPA", "COPZ1", "COQ5", "CORO1B", "CORO1C", "CPOX", "CRYZ", "CSTB", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4B", "CYP51A1", "DCAF13", "DCAF7", "DCPS", "DCXR", "DDT", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX6", "DHCR7", "DHDDS", "DHFR", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX30", "DHX36", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIS3", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC2", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DRG1", "DRG2", "DSC2", "DSG2", "DST", "DTYMK", "DYNLL1", "DYNLL2", "EARS2", "ECH1", "ECHS1", "ECI1", "ECI2", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EIF3I", "EIF4A1", "EIF4A3", "EIF4E", "ENO1", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPRS", "EPS15", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FBL", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FOXC1", "FUCA1", "FUCA2", "GAA", "GALK1", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GLA", "GLB1", "GLO1", "GMPPB", "GNPDA1", "GNS", "GOLGA2", "GPI", "GPX8", "GRHPR", "GRWD1", "GSPT1", "GTF3C2", "GUSB", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HGS", "HIBADH", "HLA-A", "HLA-B", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMOX1", "HMOX2", "HSD17B10", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "ILVBL", "IMPAD1", "IMPDH2", "INA", "IQGAP1", "IQGAP2", "IVD", "KDM2A", "KDM5A", "KDSR", "KIF11", "KIF13B", "KIF1A", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "LAMP1", "LARS", "LARS2", "LBR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK3", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME1", "ME2", "MGST2", "MID1", "MIF", "MPHOSPH8", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPST", "MRC2", "MRPL24", "MRPL3", "MRPS11", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "ND1", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFV1", "NEFL", "NEFM", "NES", "NF1", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NOTCH2", "NSD2", "NSF", "NTHL1", "NUDT1", "NUDT12", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OSGEP", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PBRM1", "PCNA", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDSS1", "PEBP1", "PEPD", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHF2", "PHF3", "PHF8", "PHGDH", "PHIP", "PHRF1", "PI4KA", "PI4KB", "PIK3C2A", "PIK3C3", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PNP", "PNPLA6", "PNPO", "POLA1", "POLD1", "POLR1B", "POLR1C", "POLR2B", "POLR2C", "POLR2E", "POLR2F", "PPIB", "PPIC", "PPID", "PPIF", "PPIH", "PPIL1", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PRPS2", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PWP2", "PYGB", "PYGL", "QARS", "QDPR", "RACK1", "RAE1", "RANBP2", "RARS", "RCL1", "RDH13", "RDX", "RIDA", "RNF14", "RNF20", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS24", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RPUSD2", "RRP8", "RSF1", "RTCA", "RTN4IP1", "S100A10", "S100A11", "SART1", "SBDS", "SCD", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB6", "SERPINH1", "SLC15A4", "SLC1A5", "SLC27A4", "SLC2A1", "SLC37A4", "SLIT2", "SMARCA4", "SMU1", "SNRNP40", "SNU13", "SORD", "SPATA5", "SPATA5L1", "SPTBN1", "SPTBN2", "SRCAP", "SRM", "STAM", "STMN1", "STOM", "STRN", "STX10", "STX12", "STX17", "STX18", "STX3", "STX5", "STX6", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SV2A", "SYNE2", "TAP1", "TBL3", "TCP1", "THOC6", "TK1", "TLN1", "TMX1", "TMX3", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRIM21", "TRIM25", "TRIM28", "TRIM33", "TRIP13", "TRMT11", "TSFM", "TSPAN10", "TSPAN6", "TUBB", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUFM", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UBA5", "UHRF1", "USP10", "USP11", "USP14", "USP19", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VARS2", "VAT1", "VCL", "VCP", "VIM", "VPS4B", "WARS", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR36", "WDR41", "WDR5", "WDR61", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2"], "leading_proteins": ["ACTR1A", "CASK", "FUCA2", "HADH", "HMOX1", "INA", "MPP1", "MPP2", "MPP7", "MRC2", "MRPS5", "NEFL", "P4HB", "PDSS1", "PHGDH", "POLR2B", "PSMB2", "PSMB4", "S100A11", "SLIT2", "STX17", "STX18", "STX3", "STX5", "STX6", "STX7", "SV2A", "TMX3", "TMX4", "TSPAN6", "TUBB", "TUBB4A", "TUBB4B", "TUBB6", "VIM", "YWHAB", "YWHAE", "YWHAH", "YWHAQ", "YWHAZ"]}

interpro_domain/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "Target SNARE coiled-coil homology domain [IPR000727]", "1": "Importin-beta, N-terminal domain [IPR001494]"}

interpro_domain/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Target SNARE coiled-coil homology domain [IPR000727]", "1": "Importin-beta, N-terminal domain [IPR001494]", "2": "Phospholipid/glycerol acyltransferase [IPR002123]", "3": "EF-hand domain [IPR002048]", "4": "Major facilitator superfamily domain [IPR020846]", "5": "Band 7 domain [IPR001107]", "6": "14-3-3 domain [IPR023410]", "7": "Small GTP-binding protein domain [IPR005225]"}

interpro_domain/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:a0bb4f6410019bcf9d3cbf464b831647c3ae47730c7b07acdd033d179ffe4656
+size 304179

interpro_domain/df_merge.tsv

@@ -0,0 +1,6 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+Target SNARE coiled-coil homology domain [IPR000727]	8	12	2.5048035358053213	0.0122519427380496	3.5024271844660193	8.266990291262136	0.5942034778060385	0.4012381903331891	1.9023475359698396	2.183694577914796	1.0582363712887182	0.3038263160802639	0.0136183078461816	1.0	1.0	0.4587195489148998	0.0001380877092489
+Importin-beta, N-terminal domain [IPR001494]	8	13	2.422400514640592	0.0154183468266064	6.385922330097087	13.28883495145631	0.1695856896111973	0.5104356360219653	3.297409379395681	0.8134617396566306	1.1027535719761996	0.3475482514742156	0.4813935862458969	1.0	1.0	0.3411306657380243	0.0468003866103798
+Peptidase M1, membrane alanine aminopeptidase [IPR014782]	3	5	2.138097496124056	0.0325088311202219	2.121359223300971	5.466019417475728	1.4317001483019938	0.1783942022754649	1.021530403905949	0.5881604361499402	0.986353205880356	0.2226891741813114	0.0001254368379847	1.0	0.0743799864466655	0.0148625463558957	0.0003311660608568
+Aminopeptidase N-like , N-terminal domain [IPR045357]	3	5	2.138097496124056	0.0325088311202219	2.121359223300971	5.466019417475728	1.4317001483019938	0.1783942022754649	1.021530403905949	0.5881604361499402	0.986353205880356	0.2226891741813114	0.0001254368379847	1.0	0.0743799864466655	0.0148625463558957	0.0003311660608568
+Cytochrome b5-like heme/steroid binding domain [IPR001199]	2	6	1.9622407626612277	0.049734460230614	2.813106796116505	6.104368932038835	1.6405397264547834	0.1100883340733615	1.2852875686886795	0.8042848477475721	1.100790504333474	0.1612592696854457	0.0091783194539023	0.0561990347849709	0.1094892401774078	0.0328731354880699	0.0181181417645757

interpro_domain/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3040,
+    "annotations_size": 2522,
+    "title": "Average number of proteins per term",
+    "value": 2.120539254559873
+}

interpro_domain/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C293/C293_val_log2fc"}

interpro_domain/result.tsv

@@ -0,0 +1,190 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Target SNARE coiled-coil homology domain [IPR000727]	0.6972206788968138	2.5048035358053213	0.0122519427380496	0.9999999999999686	0.1276745511673693	12	Q86Y82,P56962,O15400,O43752,Q13277,Q9UEU0,O15155,Q13190	8
+Importin-beta, N-terminal domain [IPR001494]	0.6557478622551338	2.422400514640592	0.0154183468266064	1.0	0.1309527677047245	13	Q8TEX9,Q92973,O43592,O15397,O95373,P55060,Q96P70,Q9HAV4	8
+Peptidase M1, membrane alanine aminopeptidase [IPR014782]	0.8246657077284575	2.138097496124056	0.0325088311202219	1.0	0.1646392377153801	5	Q9NZ08,P09960,Q9UIQ6	3
+Aminopeptidase N-like , N-terminal domain [IPR045357]	0.8246657077284575	2.138097496124056	0.0325088311202219	1.0	0.1646392377153801	5	Q9NZ08,P09960,Q9UIQ6	3
+Cytochrome b5-like heme/steroid binding domain [IPR001199]	0.7376110304708573	1.9622407626612273	0.049734460230614	1.0	0.2076660740092856	6	O43169,O15173	2
+Immunoglobulin-like domain [IPR007110]	0.6747728879662407	1.931689330184856	0.0533978625090136	1.0	0.2157788971293487	9	P10321,P35613,P04439,Q08722	4
+P-type ATPase, haloacid dehalogenase domain [IPR044492]	0.7288478249605723	1.9206876619717992	0.0547710959997362	1.0	0.2170187342356873	6	P16615,Q9HD20,P98194,P05023	4
+GOLD domain [IPR009038]	0.7251177669453573	1.9029459238513449	0.0570476017304217	1.0	0.2230605450606569	6	P49755,Q9Y3B3,Q15363	3
+START domain [IPR002913]	0.9631336405529912	1.815697091820387	0.0694168504246062	1.0	0.2493864626365482	2	Q14849	1
+Phospholipid/glycerol acyltransferase [IPR002123]	0.683161403384659	1.7899617008752982	0.0734600685841435	1.0	0.2548367166013893	7	Q86UL3,Q9NUQ2,Q7L5N7,Q8NF37,Q92604	5
+EF-hand domain [IPR002048]	0.4094164475637834	1.7872886283173344	0.0738908510197691	1.0	0.2555406215427682	46	O43852,P80303,Q14257,Q8IYU8,O75071,P0DP25,Q9BRK5,Q9Y680,Q6NUK1,O95302,Q02818,Q9NWM8,Q8NF37,P41208	14
+Major facilitator superfamily domain [IPR020846]	0.6719419716452145	1.734188919214408	0.0828845683948655	1.0	0.2772345908379987	7	Q14728,Q7L0J3,P11166,O43826,Q9H2V7,Q6NT16	6
+FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]	0.6054404648148898	1.722004529733052	0.0850686979392743	1.0	0.2815528296625325	10	Q9Y680,Q9NWM8,P62942,O95302	4
+Band 7 domain [IPR001107]	0.6634007185640727	1.72110799654933	0.0852312284978153	1.0	0.2817210462273793	8	Q99623,O75477,Q9UJZ1,P27105,O94905	5
+MENTAL domain [IPR019498]	0.9371296905859032	1.7058049179211745	0.0880444071795318	1.0	0.2865135418151992	2	Q14849	1
+GMP phosphodiesterase, delta subunit [IPR008015]	0.9364713627386372	1.703016916117195	0.0885649027595625	1.0	0.2868167825391938	2	A6NIH7	1
+Flavoprotein pyridine nucleotide cytochrome reductase [IPR001709]	0.9321922317314024	1.684888705552279	0.0920100460675372	1.0	0.2926221137229873	2	P16435	1
+Oxidoreductase FAD/NAD(P)-binding [IPR001433]	0.9321922317314024	1.684888705552279	0.0920100460675372	1.0	0.2926221137229873	2	P16435	1
+FAD-binding domain, ferredoxin reductase-type [IPR017927]	0.9321922317314024	1.684888705552279	0.0920100460675372	1.0	0.2926221137229873	2	P16435	1
+TRAM/LAG1/CLN8 homology domain [IPR006634]	0.8476909646031103	1.680980400442545	0.0927667216024585	1.0	0.2939166732178399	4	Q15629,Q96G23	2
+Dynamin-type guanine nucleotide-binding (G) domain [IPR030381]	0.6527247571825523	1.6379643213623651	0.1014291367379773	1.0	0.2984880780083768	7	O60313,Q8IWA4,O00429	3
+Dynamin, N-terminal [IPR045063]	0.6527247571825523	1.6379643213623651	0.1014291367379773	1.0	0.2984880780083768	7	O60313,Q8IWA4,O00429	3
+Endoplasmic reticulum vesicle transporter, N-terminal [IPR039542]	0.91310072416062	1.6038950996736852	0.10873717716534	1.0	0.3042237523049474	2	Q9Y282	1
+Endoplasmic reticulum vesicle transporter, C-terminal [IPR012936]	0.91310072416062	1.6038950996736852	0.10873717716534	1.0	0.3042237523049474	2	Q9Y282	1
+Peptidase M48 [IPR001915]	0.9101382488479148	1.5913133444710004	0.1115390751125691	1.0	0.307441509274537	2	O75844	1
+Peptidase M16, C-terminal [IPR007863]	0.635929756946517	1.5531858631748496	0.1203787376673555	1.0	0.3216050597426595	7	Q5JRX3	1
+Peptidase M16, N-terminal [IPR011765]	0.635929756946517	1.5531858631748496	0.1203787376673555	1.0	0.3216050597426595	7	Q5JRX3	1
+Reticulon [IPR003388]	0.9213039183404628	1.5392566968634347	0.1237416410570291	1.0	0.3271241286643893	3	Q9NQC3,O95197	2
+Immunoglobulin subtype 2 [IPR003598]	0.6727798944604971	1.45170454519973	0.1465837749722411	1.0	0.358916777165041	5	P35613	1
+Immunoglobulin subtype [IPR003599]	0.6727798944604971	1.45170454519973	0.1465837749722411	1.0	0.358916777165041	5	P35613	1
+Protein kinase, C-terminal [IPR017892]	0.6692802322549389	1.4354493907020287	0.1511590801758928	1.0	0.3665607694265402	5	P51812,Q05655,Q15418	3
+Cation-transporting P-type ATPase, C-terminal [IPR006068]	0.7875494071146304	1.431061098876443	0.1524127050330188	1.0	0.3673695581195915	4	P05023,P16615,P98194	3
+Cation-transporting P-type ATPase, N-terminal [IPR004014]	0.7875494071146304	1.431061098876443	0.1524127050330188	1.0	0.3673695581195915	4	P05023,P16615,P98194	3
+Tim10-like [IPR004217]	0.7823465317840146	1.409312144671934	0.158742889280623	1.0	0.3750265340499959	4	P62072,Q9Y5J9	2
+MD-2-related lipid-recognition domain [IPR003172]	0.8647136273864255	1.3982217544957078	0.1620464859685202	1.0	0.3773603302055476	2	P17900	1
+YTH domain [IPR007275]	0.6568446639172189	1.377582162685787	0.1683323312711389	1.0	0.384890425626303	5	Q7Z739,Q9Y5A9	2
+ERAP1-like C-terminal domain [IPR024571]	0.8765228844254134	1.3636927728617638	0.1726642796053845	1.0	0.3902287982901509	3	Q9NZ08,Q9UIQ6	2
+Acyl-CoA oxidase, C-terminal [IPR002655]	0.8475971033574727	1.3255444619543282	0.1849906327747317	1.0	0.4049881734877373	2	O15254	1
+FAD dependent oxidoreductase [IPR006076]	0.7602108036890642	1.3166504216056103	0.1879558292858831	1.0	0.4081785714290186	4	Q8NCN5,Q96CU9,P43304	3
+Zinc finger, CHHC-type [IPR012996]	0.8594007243990773	1.2965282922203316	0.1947935392680762	1.0	0.4121386795587988	3	P55795,P52597	2
+RBM3/CIRBP, RNA recognition motif [IPR034278]	0.8393680052666231	1.2906598807443812	0.1968216420444946	1.0	0.4157321450889576	2	Q14011	1
+Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337]	0.8373930217248196	1.2822947748660996	0.1997392602235645	1.0	0.4183907095380647	2	O60506	1
+Ribosomal S6 kinase, N-terminal catalytic domain [IPR041906]	0.8357472021066377	1.275326216878231	0.2021938020269671	1.0	0.4221297754238502	2	P51812	1
+LEM domain [IPR003887]	0.5916100941755201	1.2491996850246008	0.2115920471821648	1.0	0.4345563053692343	6	Q86XL3,P42167	2
+CARG-binding factor, N-terminal [IPR012956]	0.8206056616194872	1.211333138357468	0.2257677531463162	1.0	0.4504638239201025	2	Q99729	1
+Syntaxin, N-terminal domain [IPR006011]	0.8320711228185693	1.1895180192225572	0.234235884581734	1.0	0.4568777269258572	3	Q13277,O15400	2
+ATPase family AAA domain-containing protein 3, N-terminal [IPR021911]	0.8120473996050039	1.1752761628146475	0.2398842479519007	1.0	0.4621757626697431	2	Q5T9A4	1
+Dynamin, GTPase domain [IPR001401]	0.8267694017136431	1.168809173180804	0.2424805236913727	1.0	0.4636359975357407	3	O60313	1
+Intermediate filament head, DNA-binding domain [IPR006821]	0.7246376811594191	1.1676142170505406	0.2429624128563206	1.0	0.4642054585027579	4	Q16352,P07196,P08670	3
+Choline/carnitine acyltransferase domain [IPR039551]	0.8097432521395419	1.1655850178297382	0.2437822681858401	1.0	0.4650884297092342	2	P23786	1
+Alpha-L-fucosidase, C-terminal [IPR031919]	0.8077682685977624	1.1572843432935744	0.2471562080862368	1.0	0.4679065220169759	2	Q9BTY2	1
+N-acetylgalactosaminyltransferase [IPR045885]	0.8028308097432348	1.1365583189788224	0.2557229727866255	1.0	0.4752640658569414	2	Q10472	1
+TGS [IPR004095]	0.5659462380894109	1.1206781020253926	0.2624249065706978	1.0	0.4827393248514223	6	Q9NTK5	1
+Intermediate filament, rod domain [IPR039008]	0.5447771795255602	1.106847540018514	0.2683598502282822	1.0	0.4890399374154204	8	Q16352,P07196,P08670	3
+Far upstream element-binding protein, C-terminal [IPR015096]	0.7863726135615546	1.067773275032234	0.2856227960149549	1.0	0.5008892273532343	2	Q92945	1
+Glycosyltransferase 2-like [IPR001173]	0.7958511689166861	1.048583732668242	0.2943697460616148	1.0	0.5088831660328128	3	Q10472,Q10471	2
+3-hydroxyacyl-CoA dehydrogenase, NAD binding [IPR006176]	0.7722185648452711	1.0090634346706262	0.3129442127738726	1.0	0.5251133097908894	2	Q16836	1
+3-hydroxyacyl-CoA dehydrogenase, C-terminal [IPR006108]	0.7722185648452711	1.0090634346706262	0.3129442127738726	1.0	0.5251133097908894	2	Q16836	1
+Phosphatidylinositol 3-/4-kinase, catalytic domain [IPR000403]	0.5262956557902334	0.988882808141752	0.3227204828175041	1.0	0.5337056115840954	7	Q8NEB9,Q9BTU6	2
+Sam68, tyrosine-rich domain [IPR032335]	0.7639894667544336	0.9751562967795592	0.3294827368120838	1.0	0.5390666935806543	2	O75525	1
+KHDRBS, Qua1 domain [IPR032571]	0.7639894667544336	0.9751562967795592	0.3294827368120838	1.0	0.5390666935806543	2	O75525	1
+Prolyl 4-hydroxylase alpha-subunit, N-terminal [IPR013547]	0.7613561553653727	0.9643451808247772	0.3348728962745131	1.0	0.5434681109422922	2	P13674	1
+Post-SET domain [IPR003616]	0.7570770243581314	0.946820248068699	0.34373038220682	1.0	0.5521657448089982	2	O96028	1
+FAD-binding domain, PCMH-type [IPR016166]	0.7551020408162946	0.9387504906198344	0.3478588636305602	1.0	0.5531592866538241	2	Q15392	1
+FAD linked oxidase, N-terminal [IPR006094]	0.7551020408162946	0.9387504906198344	0.3478588636305602	1.0	0.5531592866538241	2	Q15392	1
+Glycoside hydrolase family 2, catalytic domain [IPR006103]	0.7534562211981355	0.932034990706798	0.3513184426021958	1.0	0.5551146485434272	2	P08236	1
+Rhodanese-like domain [IPR001763]	0.7643785273162309	0.9276389234799426	0.3535949000509419	1.0	0.5565842655270653	3	Q8NCN5	1
+Acyltransferase, C-terminal domain [IPR032098]	0.747860434496349	0.909267860819746	0.3632087510947897	1.0	0.5638258130107159	2	Q9NUQ2	1
+Lysophosphatidylcholine acyltransferase LPCAT1-like [IPR045252]	0.7566677642410211	0.8983167188599119	0.369016721720242	1.0	0.5674757147429575	3	Q8NF37,Q7L5N7	2
+Fzo/mitofusin HR2 domain [IPR006884]	0.7369980250164592	0.8653830946730866	0.3868285565971101	1.0	0.5866395789163631	2	Q8IWA4	1
+Acyl transferase [IPR014043]	0.7314022383146664	0.8429492735141532	0.3992568144029624	1.0	0.5965199561162745	2	Q8IVS2	1
+Exportin-2, central domain [IPR013713]	0.7411919657556681	0.8399272057211852	0.400949202619806	1.0	0.5966835312734471	3	O95373,O15397	2
+Peptidase M14, carboxypeptidase A [IPR000834]	0.7300855826201459	0.8376889984927226	0.4022053938004997	1.0	0.5966835312734471	2	P16870	1
+AGC-kinase, C-terminal [IPR000961]	0.4937360578534181	0.820825277880337	0.4117457979751333	1.0	0.6013125789757813	7	P51812,Q05655	2
+CBS domain [IPR000644]	0.5316424429430557	0.7946545499202847	0.4268144773667397	1.0	0.6119534462301977	5	Q8NE01,P51790,P51798	3
+C-type lectin-like [IPR001304]	0.708689927583938	0.7532865433381917	0.4512777433862711	1.0	0.6329935866630566	2	Q9UBG0	1
+CD209-like, C-type lectin-like domain [IPR033989]	0.708689927583938	0.7532865433381917	0.4512777433862711	1.0	0.6329935866630566	2	Q9UBG0	1
+ALIX V-shaped domain [IPR025304]	0.7057274522712322	0.741774251739728	0.4582241234001183	1.0	0.6381232684787953	2	Q8WUM4	1
+NOPS [IPR012975]	0.714208977060188	0.7399081629192553	0.4593557209953567	1.0	0.6386411953419457	3	P23246	1
+Survival motor neuron [IPR010304]	0.7050691244239644	0.7392221947665739	0.4597720856764904	1.0	0.638867878829812	2	Q16637	1
+Peptidase M28 [IPR007484]	0.7138623641751605	0.7386405164874003	0.4601253146075899	1.0	0.6390066318504084	3	Q7Z2K6,Q969V3	2
+Glutathione S-transferase, N-terminal [IPR004045]	0.4767592010945922	0.734075728715576	0.4629025851613702	1.0	0.6403951287860535	7	P78417	1
+Fibronectin type II domain [IPR000562]	0.7051483936889498	0.706932457790595	0.4796084522219637	1.0	0.6552397164159223	3	Q9UBV2	1
+Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, N-terminal [IPR018955]	0.6942067149440434	0.697455452084912	0.4855178089905698	1.0	0.6597391779494703	2	Q15118	1
+Histidine kinase domain [IPR005467]	0.6942067149440434	0.697455452084912	0.4855178089905698	1.0	0.6597391779494703	2	Q15118	1
+OCRE domain [IPR041591]	0.7011976335553154	0.692662970617506	0.4885210823930692	1.0	0.6623925644060863	3	P78332	1
+Fatty acid desaturase domain [IPR005804]	0.6909150757077022	0.684932140160956	0.4933867434774266	1.0	0.6679127037305796	2	O95864	1
+Armadillo repeat-containing domain [IPR006911]	0.6988216919193596	0.6841149639884729	0.4939025733933828	1.0	0.6682523015547808	3	Q9UH62	1
+Proteasome activator PA28, N-terminal domain [IPR003185]	0.6875085274454442	0.6437775093683131	0.5197197199698267	1.0	0.6858434719602124	3	P61289	1
+Proteasome activator PA28, C-terminal domain [IPR003186]	0.6875085274454442	0.6437775093683131	0.5197197199698267	1.0	0.6858434719602124	3	P61289	1
+Tim44-like domain [IPR007379]	0.672481895984186	0.6160624403263176	0.537853310132802	1.0	0.6981297211296585	2	O43615	1
+Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862]	0.5794574542304747	0.5791633086659539	0.5624789857327446	1.0	0.7118225754294308	4	P13674	1
+Zinc finger C2H2 AKAP95-type [IPR034736]	0.6657886071781378	0.5682086876921895	0.5698932730295472	1.0	0.7142651031691902	3	O43823,Q5BKZ1	2
+Ubiquitin carboxyl-terminal hydrolase, C-terminal [IPR029346]	0.6533903884134313	0.5472601291703351	0.5842000316068898	1.0	0.7232952772275779	2	P51784	1
+DNA2/NAM7 helicase-like, C-terminal [IPR041679]	0.5654042866671739	0.5265678888751387	0.5984936959831857	1.0	0.7348593482325192	4	P51530	1
+EGF-like calcium-binding domain [IPR001881]	0.6445029624753141	0.5162199165978113	0.605700821436691	1.0	0.7397469596432614	2	O94813	1
+EXPERA domain [IPR033118]	0.6431863067807669	0.511678680442838	0.6088759093784206	1.0	0.7425459591162364	2	Q15125	1
+Peptidase M3A/M3B catalytic domain [IPR001567]	0.648007902535388	0.5084563364862499	0.6111333527631373	1.0	0.7432909045811918	3	P52888,Q99797	2
+CTP synthase, N-terminal [IPR017456]	0.6421988150098763	0.5082827157566613	0.6112550896516225	1.0	0.7432909045811918	2	P17812	1
+CTP synthase GATase domain [IPR033828]	0.6421988150098763	0.5082827157566613	0.6112550896516225	1.0	0.7432909045811918	2	P17812	1
+Tubulin/FtsZ, GTPase domain [IPR003008]	0.4629324546952166	0.4922666050273103	0.6225308847600726	1.0	0.7488644097634792	5	P07437,P04350,P68371,Q9BUF5	4
+Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]	0.4629324546952166	0.4922666050273103	0.6225308847600726	1.0	0.7488644097634792	5	P07437,P04350,P68371,Q9BUF5	4
+Ricin B, lectin domain [IPR000772]	0.555596468216081	0.4906553050339914	0.6236702632535678	1.0	0.7495586756818574	4	Q10471,Q10472	2
+L27 domain [IPR004172]	0.5509296594697239	0.4738168749135019	0.6356304999480664	1.0	0.7550919080871519	4	Q14168,O14936	2
+L27 domain, C-terminal [IPR014775]	0.5509296594697239	0.4738168749135019	0.6356304999480664	1.0	0.7550919080871519	4	Q14168,O14936	2
+Extended PHD (ePHD) domain [IPR034732]	0.6351401169919408	0.4665677542799357	0.6408091618618088	1.0	0.7573199185639559	3	P55201	1
+Glutathione S-transferase, C-terminal [IPR004046]	0.4039860071847124	0.4571447977375019	0.6475669728843134	1.0	0.7613817741791321	9	P78417	1
+v-SNARE, coiled-coil homology domain [IPR042855]	0.6289101086598504	0.4467327158788886	0.6550680571731262	1.0	0.7655252892381933	3	O75396,O15498	2
+Longin domain [IPR010908]	0.6289101086598504	0.4467327158788886	0.6550680571731262	1.0	0.7655252892381933	3	O75396,O15498	2
+EF hand associated, type-1 [IPR013566]	0.614219881500989	0.4158606263320394	0.6775119925476261	1.0	0.7773818222043279	2	Q8IXI1	1
+EF hand associated, type-2 [IPR013567]	0.614219881500989	0.4158606263320394	0.6775119925476261	1.0	0.7773818222043279	2	Q8IXI1	1
+MIRO domain [IPR020860]	0.614219881500989	0.4158606263320394	0.6775119925476261	1.0	0.7773818222043279	2	Q8IXI1	1
+GYF domain [IPR003169]	0.6129032258064532	0.4117038664623369	0.6805564906789405	1.0	0.7794566164815113	2	O95400	1
+EGF-like domain [IPR000742]	0.5329380764163305	0.410554012186051	0.6813995906969224	1.0	0.7796341608809252	4	Q04721,P07942,O94813	3
+14-3-3 domain [IPR023410]	0.3991430454845158	0.3245130311572731	0.7455496581804859	1.0	0.8180597237704639	6	P27348,P31946,P62258,P63104,Q04917	5
+NIPSNAP [IPR012577]	0.5789993416721473	0.3113686114036472	0.7555204131816688	1.0	0.8255729991525862	2	Q9BPW8	1
+Serine hydroxymethyltransferase-like domain [IPR039429]	0.5757077024358063	0.3023579050934096	0.7623792407149717	1.0	0.8323465130230123	2	P34896	1
+Glutathione S-transferase, C-terminal-like [IPR010987]	0.3449805974761165	0.2796843050140347	0.7797197207555466	1.0	0.8463457242898809	11	P78417	1
+MHC class I alpha chain, alpha1 alpha2 domains [IPR001039]	0.5707740646313952	0.278137745258272	0.7809066218963334	1.0	0.8463457242898809	3	P04439	1
+MHC class I, alpha chain, C-terminal [IPR010579]	0.5707740646313952	0.278137745258272	0.7809066218963334	1.0	0.8463457242898809	3	P04439	1
+MHC class I-like antigen recognition-like [IPR011161]	0.5707740646313952	0.278137745258272	0.7809066218963334	1.0	0.8463457242898809	3	P04439	1
+Immunoglobulin C1-set [IPR003597]	0.5707740646313952	0.278137745258272	0.7809066218963334	1.0	0.8463457242898809	3	P04439	1
+Immunoglobulin I-set [IPR013098]	0.5552995391705089	0.2496086079939673	0.802890041054916	1.0	0.8660772812405895	2	Q8WX93	1
+S100/CaBP-9k-type, calcium binding, subdomain [IPR013787]	0.5543120473996068	0.2471960724604582	0.8047564847288204	1.0	0.8666990673503208	2	P31949	1
+Small GTP-binding protein domain [IPR005225]	0.2650125923949026	0.239416103095175	0.8107829445803789	1.0	0.8727249621134082	43	Q15907,Q969Q5,P61225,P61026,Q9NR31	5
+Exocyst complex component EXOC2/Sec5, N-terminal domain [IPR039481]	0.5490454246214632	0.2345527546447525	0.8145558828874022	1.0	0.8752918349561263	2	Q96KP1	1
+Exosome complex component, N-terminal domain [IPR025721]	0.542462146148784	0.2192833533088098	0.8264293284867223	1.0	0.8850338711012797	2	Q13868	1
+Laminin-type EGF domain [IPR002049]	0.5325872284397648	0.1975094055812257	0.8434289218223627	1.0	0.8994197635670185	2	P07942	1
+Laminin, N-terminal [IPR008211]	0.5325872284397648	0.1975094055812257	0.8434289218223627	1.0	0.8994197635670185	2	P07942	1
+Domain of unknown function DUF5600 [IPR040990]	0.5240289664252817	0.1797494517762456	0.8573492687633022	1.0	0.9096486562141556	2	Q9H223	1
+EH domain-containing protein, N-terminal [IPR031692]	0.5240289664252817	0.1797494517762456	0.8573492687633022	1.0	0.9096486562141556	2	Q9H223	1
+CS domain [IPR007052]	0.3420650019157856	0.1594592259959996	0.8733070801678102	1.0	0.9246349522179754	9	Q9P035	1
+eRF1 domain 1/Pelota-like [IPR005140]	0.5046082949308776	0.1433108810697478	0.8860446626858707	1.0	0.9343682794666934	2	Q9BRX2	1
+eRF1 domain 2 [IPR005141]	0.5046082949308776	0.1433108810697478	0.8860446626858707	1.0	0.9343682794666934	2	Q9BRX2	1
+eRF1 domain 3 [IPR005142]	0.5046082949308776	0.1433108810697478	0.8860446626858707	1.0	0.9343682794666934	2	Q9BRX2	1
+Synaptotagmin-like mitochondrial-lipid-binding domain [IPR031468]	0.5039499670836096	0.1421697308947871	0.886945940144038	1.0	0.9343682794666934	2	Q9BSJ8	1
+Extended synaptotagmin, C-terminal C2 domain [IPR037752]	0.5039499670836096	0.1421697308947871	0.886945940144038	1.0	0.9343682794666934	2	Q9BSJ8	1
+Extended synaptotagmin, C2B domain [IPR037749]	0.5039499670836096	0.1421697308947871	0.886945940144038	1.0	0.9343682794666934	2	Q9BSJ8	1
+Extended synaptotagmin, C2A domain [IPR037733]	0.5039499670836096	0.1421697308947871	0.886945940144038	1.0	0.9343682794666934	2	Q9BSJ8	1
+Synaptotagmin, SMP domain [IPR039010]	0.5039499670836096	0.1421697308947871	0.886945940144038	1.0	0.9343682794666934	2	Q9BSJ8	1
+Clp ATPase, C-terminal [IPR019489]	0.5019749835418057	0.1387831620577591	0.8896214999434715	1.0	0.936528180144986	2	Q9H078	1
+AP complex, mu/sigma subunit [IPR022775]	0.3473983714647487	0.1295778678010423	0.8969004145321788	1.0	0.942492852270898	6	Q9Y2T2	1
+Domain of unknown function DUF4217 [IPR025313]	0.4957208689927604	0.1284229453454184	0.8978142737427082	1.0	0.9430602242311996	2	Q9NVP1	1
+COMM domain [IPR017920]	0.4944042132982245	0.1263120696399414	0.899484902590991	1.0	0.9440286826194256	2	Q9H0A8	1
+GRAM domain [IPR004182]	0.4972011853802952	0.1176499674887013	0.9063450115088632	1.0	0.9483448800762374	3	Q66K14,Q969T9	2
+Thioredoxin domain [IPR013766]	0.2683689470496647	0.1175619059808458	0.906414790193964	1.0	0.9483448800762374	25	P07237,Q96JJ7,Q9H1E5	3
+RNA polymerase Rpb2, domain 7 [IPR007641]	0.4878209348255453	0.1161215152916007	0.9075562374250016	1.0	0.9483448800762374	2	P30876	1
+RNA polymerase, beta subunit, protrusion [IPR007644]	0.4878209348255453	0.1161215152916007	0.9075562374250016	1.0	0.9483448800762374	2	P30876	1
+RNA polymerase Rpb2, domain 3 [IPR007645]	0.4878209348255453	0.1161215152916007	0.9075562374250016	1.0	0.9483448800762374	2	P30876	1
+RNA polymerase Rpb2, domain 2 [IPR007642]	0.4878209348255453	0.1161215152916007	0.9075562374250016	1.0	0.9483448800762374	2	P30876	1
+DNA-directed RNA polymerase, subunit 2, hybrid-binding domain [IPR007120]	0.4878209348255453	0.1161215152916007	0.9075562374250016	1.0	0.9483448800762374	2	P30876	1
+Peptidase M41 [IPR000642]	0.4871626069782773	0.1151356422504906	0.9083376093149738	1.0	0.9485827953177488	2	Q96TA2	1
+Heat shock chaperonin-binding [IPR006636]	0.4265480895915682	0.1092616965960962	0.9129949263461564	1.0	0.951869865334852	4	Q9NRR5,P31948,Q9UHD9	3
+Potassium channel tetramerisation-type BTB domain [IPR003131]	0.479262672811062	0.1037707969247223	0.91735124200006	1.0	0.9554702038527207	2	Q96CX2	1
+BRO1 domain [IPR004328]	0.4796624161576428	0.0893022655256237	0.9288416936364196	1.0	0.9648017921544688	3	Q8WUM4	1
+STAT transcription factor, DNA-binding [IPR013801]	0.466754443712971	0.0875020936722851	0.9302724213066218	1.0	0.9650954531202386	2	P42224	1
+STAT transcription factor, all-alpha domain [IPR013800]	0.466754443712971	0.0875020936722851	0.9302724213066218	1.0	0.9650954531202386	2	P42224	1
+STAT transcription factor, protein interaction [IPR013799]	0.466754443712971	0.0875020936722851	0.9302724213066218	1.0	0.9650954531202386	2	P42224	1
+Ribosomal protein S4/S9, N-terminal [IPR001912]	0.4598420013166578	0.0793926070693063	0.9367203487854984	1.0	0.9709859102494974	2	Q9NV31	1
+FAD/NAD(P)-binding domain [IPR023753]	0.3397034596375631	0.0736231312005906	0.9413102650486578	1.0	0.9729444624806208	5	P00390,O95831,P22570,P09622	4
+RuvB-like, AAA-lid domain [IPR041048]	0.4509545753785409	0.0698534742445866	0.9443102847941728	1.0	0.9748467205284094	2	Q9Y230	1
+TIP49, P-loop domain [IPR010339]	0.4509545753785409	0.0698534742445866	0.9443102847941728	1.0	0.9748467205284094	2	Q9Y230	1
+Ancestral coatomer element 1, Sec16/Sec31 [IPR024298]	0.4473337722185671	0.0662447338251204	0.9471829825249392	1.0	0.9774122266480756	2	O15027	1
+Rpn11/EIF3F, C-terminal [IPR024969]	0.4021739130434794	0.0622109983245828	0.9503948040601248	1.0	0.9803254379712208	4	P51665,O00487,Q7L5N1	3
+Heterogeneous nuclear ribonucleoprotein U, SPRY domain [IPR035778]	0.4560051519719069	0.0571413243604649	0.9544326181020616	1.0	0.9815224862891874	3	Q9BUJ2	1
+Rab-GTPase-TBC domain [IPR000195]	0.3324546952224106	0.0569160432274301	0.954612074381966	1.0	0.9815224862891874	5	Q66K14,Q9BXI6,Q8TC07,Q9Y3P9	4
+Ribosomal protein S5, N-terminal [IPR013810]	0.4282422646477968	0.0497229101535463	0.9603431993759924	1.0	0.9843571822730952	2	P82675	1
+Ribosomal protein S5, C-terminal [IPR005324]	0.4282422646477968	0.0497229101535463	0.9603431993759924	1.0	0.9843571822730952	2	P82675	1
+4Fe-4S ferredoxin-type, iron-sulphur binding domain [IPR017896]	0.4495959513029675	0.0495939377783053	0.9604459776412424	1.0	0.9843571822730952	3	P21912	1
+SCP2 sterol-binding domain [IPR003033]	0.4487981560750693	0.0486882486247173	0.9611677410087412	1.0	0.9843571822730952	3	Q6YN16,P51659	2
+Kinesin-associated [IPR032405]	0.426596445029627	0.0484859007866961	0.9613290007686888	1.0	0.9843571822730952	2	Q9NQT8	1
+Kinesin-like KIF1-type [IPR022140]	0.426596445029627	0.0484859007866961	0.9613290007686888	1.0	0.9843571822730952	2	Q9NQT8	1
+SET domain [IPR001214]	0.4471727536003965	0.046865935335276	0.9626200779115296	1.0	0.9848794468530944	3	O96028	1
+PIN domain [IPR002716]	0.3880842659644528	0.026814253373805	0.9786078847576924	1.0	0.9933364513663788	2	Q9Y2L1	1
+Kinesin-like [IPR022164]	0.4267369114257516	0.026497872716296	0.9788602303311456	1.0	0.9933364513663788	3	Q9NQT8,Q9Y3P9	2
+Agenet-like domain [IPR008395]	0.4263152376094926	0.0261255676062418	0.9791571840193568	1.0	0.9933364513663788	3	Q06787	1
+Synaptic functional regulator FMRP, KH0 domain [IPR040472]	0.4263152376094926	0.0261255676062418	0.9791571840193568	1.0	0.9933364513663788	3	Q06787	1
+Fragile X-related 1 protein, C-terminal core [IPR022034]	0.4263152376094926	0.0261255676062418	0.9791571840193568	1.0	0.9933364513663788	3	Q06787	1
+Fxr1, tudor domain [IPR041560]	0.4263152376094926	0.0261255676062418	0.9791571840193568	1.0	0.9933364513663788	3	Q06787	1
+Fragile X-related 1 protein, C-terminal region 1 [IPR032172]	0.3489137590520104	0.0157328055906912	0.9874475551558533	1.0	1.0	2	P51114	1
+ELMO domain [IPR006816]	0.3466096115865726	0.015322646368728	0.9877747754137742	1.0	1.0	2	Q8IZ81	1
+RNA-binding S4 domain [IPR002942]	0.4089562067830116	0.0123713027484272	0.9901293803222826	1.0	1.0	3	P46781,Q9NV31	2
+PIK-related kinase [IPR014009]	0.3179723502304176	0.0117466039883336	0.9906277815703476	1.0	1.0	2	P42345	1
+FATC domain [IPR003152]	0.3179723502304176	0.0117466039883336	0.9906277815703476	1.0	1.0	2	P42345	1
+PIK-related kinase, FAT [IPR003151]	0.3179723502304176	0.0117466039883336	0.9906277815703476	1.0	1.0	2	P42345	1
+Transcription factor IIS, N-terminal [IPR017923]	0.3166556945358817	0.0116374331846169	0.9907148813154658	1.0	1.0	2	Q96ST2	1
+Lsm14-like, N-terminal [IPR025609]	0.2939433838051376	0.0102802079431563	0.9917977252736232	1.0	1.0	2	Q9BX40	1
+DFDF domain [IPR025762]	0.2939433838051376	0.0102802079431563	0.9917977252736232	1.0	1.0	2	Q9BX40	1
+FDF domain [IPR019050]	0.2939433838051376	0.0102802079431563	0.9917977252736232	1.0	1.0	2	Q9BX40	1

interpro_family/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "Mitochondrial carrier protein [IPR002067]", "1": "Syntaxin [IPR045242]"}

interpro_family/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Mitochondrial carrier protein [IPR002067]", "1": "Syntaxin [IPR045242]", "2": "Small GTPase [IPR001806]", "3": "Short-chain dehydrogenase/reductase SDR [IPR002347]", "4": "14-3-3 protein [IPR000308]"}