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- interpro_active_site/advanced/idx2term.json +1 -0
- interpro_active_site/basic/idx2term.json +1 -0
- interpro_active_site/consensus.joblib +3 -0
- interpro_active_site/df_merge.tsv +1 -0
- interpro_active_site/metrics.json +7 -0
- interpro_active_site/paths.json +1 -0
- interpro_active_site/result.tsv +7 -0
- interpro_active_site/selections.json +1 -0
- interpro_binding_site/advanced/idx2term.json +1 -0
- interpro_binding_site/advanced/plot_0.png +3 -0
- interpro_binding_site/basic/idx2term.json +1 -0
- interpro_binding_site/basic/plot_0.png +3 -0
- interpro_binding_site/basic/plot_1.png +3 -0
- interpro_binding_site/consensus.joblib +3 -0
- interpro_binding_site/df_merge.tsv +2 -0
- interpro_binding_site/metrics.json +7 -0
- interpro_binding_site/paths.json +1 -0
- interpro_binding_site/result.tsv +4 -0
- interpro_binding_site/selections.json +1 -0
- interpro_conserved_site/advanced/idx2term.json +1 -0
- interpro_conserved_site/advanced/plot_0.png +3 -0
- interpro_conserved_site/advanced/plot_1.png +3 -0
- interpro_conserved_site/basic/idx2term.json +1 -0
- interpro_conserved_site/basic/plot_0.png +3 -0
- interpro_conserved_site/basic/plot_1.png +3 -0
- interpro_conserved_site/basic/plot_2.png +3 -0
- interpro_conserved_site/consensus.joblib +3 -0
- interpro_conserved_site/df_merge.tsv +4 -0
- interpro_conserved_site/metrics.json +7 -0
- interpro_conserved_site/paths.json +1 -0
- interpro_conserved_site/result.tsv +27 -0
- interpro_conserved_site/selections.json +1 -0
- interpro_domain/advanced/idx2term.json +1 -0
- interpro_domain/advanced/plot_0.png +3 -0
- interpro_domain/advanced/plot_1.png +3 -0
- interpro_domain/advanced/plot_2.png +3 -0
- interpro_domain/advanced/plot_3.png +3 -0
- interpro_domain/advanced/plot_4.png +3 -0
- interpro_domain/advanced/plot_5.png +3 -0
- interpro_domain/advanced/plot_6.png +3 -0
- interpro_domain/basic/idx2term.json +1 -0
- interpro_domain/basic/plot_0.png +3 -0
- interpro_domain/basic/plot_1.png +3 -0
- interpro_domain/basic/plot_10.png +3 -0
- interpro_domain/basic/plot_11.png +3 -0
- interpro_domain/basic/plot_12.png +3 -0
- interpro_domain/basic/plot_13.png +3 -0
- interpro_domain/basic/plot_14.png +3 -0
- interpro_domain/basic/plot_2.png +3 -0
- interpro_domain/basic/plot_3.png +3 -0
interpro_active_site/advanced/idx2term.json
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{}
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interpro_active_site/basic/idx2term.json
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{}
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interpro_active_site/consensus.joblib
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version https://git-lfs.github.com/spec/v1
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oid sha256:bdfda589d60a1c051f9f0d32a995692b80ba482d0b4ce88cd76a72c77f33cb1c
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size 71820
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interpro_active_site/df_merge.tsv
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term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500
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interpro_active_site/metrics.json
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{
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"type_of_task": "ranksum",
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"signature_size": 3053,
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"annotations_size": 53,
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"title": "Average number of proteins per term",
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"value": 2.792452830188679
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}
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interpro_active_site/paths.json
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{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C310/C310_val_log2fc"}
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interpro_active_site/result.tsv
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Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
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Serine carboxypeptidase, serine active site [IPR018202] 0.9150819672131104 1.645783258843623 0.0998083901999997 0.9962002683859263 0.2784128779263151 3 Q9HB40,P10619 2
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Tyrosine-protein kinase, active site [IPR008266] 0.6664708104613555 1.5548668838308703 0.119977775831455 0.998856692848006 0.3088638282491021 7 P08069,Q15375,P00533 3
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Cysteine peptidase, asparagine active site [IPR025661] 0.9442805637495966 1.5212080864701785 0.128207626820382 0.9993051477615444 0.3088638282491021 2 P07858 1
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Cysteine peptidase, histidine active site [IPR025660] 0.9442805637495966 1.5212080864701785 0.128207626820382 0.9993051477615444 0.3088638282491021 2 P07858 1
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Histidine acid phosphatase active site [IPR033379] 0.8574237954769084 1.1628584865159188 0.2448869229258135 0.9999996575197376 0.4635359612524327 2 P11117 1
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Cysteine peptidase, cysteine active site [IPR000169] 0.5358261087526897 0.8277239753744005 0.4078268379988903 0.9999999999991296 0.6754632004356621 6 P07858 1
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interpro_active_site/selections.json
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{"all_annotations": ["ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenylosuccinate synthase, active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glutaredoxin active site [IPR011767]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycoside hydrolase, family 2, active site [IPR023232]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Peptidase family C14A, His active site [IPR016129]", "Peptidase family C14A, cysteine active site [IPR033139]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]", "Uracil-DNA glycosylase, active site [IPR018085]"], "available_proteins": ["ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ACVR1B", "ADSS", "AKT1", "AKT2", "APEH", "ATP5A1", "ATP5B", "ATP6V1A", "ATP6V1B2", "AURKA", "BLMH", "CAMK2G", "CAPN1", "CAPN2", "CAPN5", "CASP2", "CASP3", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK9", "CHEK1", "CHEK2", "CHUK", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CTSA", "CTSB", "CTSC", "DLD", "DNMT1", "DUSP3", "EGFR", "EIF2AK2", "EPHA7", "FASN", "G6PD", "GAA", "GANAB", "GAPDH", "GART", "GLRX", "GLUD1", "GSK3A", "GSR", "GUSB", "HADHB", "HMGCL", "HMGCS1", "IGF1R", "IKBKB", "LDHA", "LDHB", "LONP1", "LYN", "MAP2K1", "MAP2K4", "MAPK1", "MAPK3", "MASTL", "MDH1", "MDH2", "MTMR2", "MTMR6", "NEK9", "NME1", "NME2", "NME3", "PAK2", "PBK", "PGAM1", "PKM", "PKN1", "PKN2", "PLK1", "PREP", "PRKACA", "PRKCD", "PRPF4B", "PTK2", "PTK7", "PTPN1", "PTPN11", "PTPRF", "RIPK1", "RNASET2", "ROCK2", "RPS6KA1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SRPK2", "SUCLG1", "TALDO1", "TIGAR", "TLK2", "TOP1", "TPI1", "TPP2", "TTK", "TXNRD1", "UBA1", "UBA2", "UBA3", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "UMPS", "UNG", "VRK1"], "leading_proteins": ["ACP2", "CTSA", "CTSB", "EGFR", "EPHA7", "IGF1R", "SCPEP1"]}
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interpro_binding_site/advanced/idx2term.json
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{"0": "EF-Hand 1, calcium-binding site [IPR018247]"}
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interpro_binding_site/advanced/plot_0.png
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interpro_binding_site/basic/idx2term.json
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{"0": "EF-Hand 1, calcium-binding site [IPR018247]", "1": "Beta tubulin, autoregulation binding site [IPR013838]"}
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interpro_binding_site/basic/plot_0.png
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interpro_binding_site/basic/plot_1.png
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interpro_binding_site/consensus.joblib
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version https://git-lfs.github.com/spec/v1
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oid sha256:92e609af18fdd6fadd61054a73f50d03bfc4e7f99812b32ce7940e131932510f
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size 69781
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interpro_binding_site/df_merge.tsv
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term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500
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EF-Hand 1, calcium-binding site [IPR018247] 15 35 2.297945259733813 0.0215649048748849 10.019417475728156 36.70631067961165 0.9532938980945532 0.3894555773109194 3.76037227687173 3.057484685571999 1.1082350706804749 0.3408841825650379 1.5102493358374857e-05 0.3175327074700926 0.0402942577421927 0.002958524345255 9.448901657314716e-07
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interpro_binding_site/metrics.json
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{
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"type_of_task": "ranksum",
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"signature_size": 3053,
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"annotations_size": 31,
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"title": "Average number of proteins per term",
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"value": 4.612903225806452
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}
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interpro_binding_site/paths.json
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{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C310/C310_val_log2fc"}
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interpro_binding_site/result.tsv
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Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
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EF-Hand 1, calcium-binding site [IPR018247] 0.5935804333599862 2.297945259733813 0.0215649048748849 0.491263758056134 0.2308828301858899 35 O95302,Q02818,Q9Y680,Q9H223,P80303,Q9H4M9,O95202,Q6NUK1,Q9BRK5,P41208,P0DP25,Q9BPX6,Q14257,Q9NWM8,O43852 15
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Beta tubulin, autoregulation binding site [IPR013838] 0.4886773875943626 0.6033890978648769 0.5462498731287617 0.9999999999770216 0.7697157303178006 6 P04350,Q9BVA1,Q9BUF5,P07437,P68371 5
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Protein kinase, ATP binding site [IPR017441] 0.326094201127647 0.1716108024169046 0.863743514350996 1.0 0.905245156023876 47 Q15375,P36896,P31751,Q86UE8 4
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interpro_binding_site/selections.json
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{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "APOBEC/CMP deaminase, zinc-binding [IPR016192]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Legume lectin, beta chain, Mn/Ca-binding site [IPR019825]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ACVR1B", "ADSS", "AKT1", "AKT2", "APEX1", "APOBEC3C", "AURKA", "BPNT1", "CALM3", "CALU", "CAMK2G", "CAPN1", "CAPN2", "CAPNS1", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK9", "CETN2", "CHEK1", "CHUK", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A2", "CYB5B", "DBT", "DLAT", "DLST", "EGFR", "EHD1", "EHD4", "EIF2AK2", "EPHA7", "FKBP10", "FKBP14", "FKBP7", "FKBP9", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3A", "HK1", "HK2", "HMBS", "IDE", "IGF1R", "ILKAP", "IQGAP1", "IQGAP2", "LETM1", "LRP2", "LYN", "MACF1", "MAP2K1", "MAP2K4", "MAP4K5", "MAPK1", "MAPK3", "MCCC1", "METAP2", "MICU1", "MYH10", "MYH14", "MYH9", "MYO1B", "MYO1C", "MYO1D", "MYO9B", "NFS1", "NRDC", "NUCB1", "NUCB2", "PA2G4", "PAK2", "PC", "PCCA", "PDCD6", "PEF1", "PGD", "PKN1", "PKN2", "PLK1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1F", "PPM1G", "PRKACA", "PRKCD", "PRKCSH", "PSAT1", "PTK2", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK2", "RPS6KA1", "RPS6KA3", "S100A11", "SDF4", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "SRPK2", "STK26", "STK4", "TBK1", "TKT", "TLK2", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "UBE3C", "UQCRC2", "VRK1"], "leading_proteins": ["ACVR1B", "AKT2", "CALM3", "CALU", "CETN2", "EHD1", "EHD4", "EPHA7", "FKBP14", "FKBP7", "FKBP9", "LETM1", "MICU1", "NUCB1", "NUCB2", "RCN2", "SDF4", "SLC25A24", "TLK2", "TUBB", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6"]}
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interpro_conserved_site/advanced/idx2term.json
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{"0": "EGF-like calcium-binding, conserved site [IPR018097]", "1": "Syntaxin/epimorphin, conserved site [IPR006012]"}
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interpro_conserved_site/advanced/plot_0.png
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interpro_conserved_site/basic/idx2term.json
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{"0": "EGF-like calcium-binding, conserved site [IPR018097]", "1": "Syntaxin/epimorphin, conserved site [IPR006012]", "2": "Tubulin, conserved site [IPR017975]"}
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interpro_conserved_site/basic/plot_0.png
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interpro_conserved_site/basic/plot_1.png
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interpro_conserved_site/basic/plot_2.png
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interpro_conserved_site/consensus.joblib
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version https://git-lfs.github.com/spec/v1
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oid sha256:f2572b644d064cd5363f6c7c618f29112a2e777b07dc929567ad1b4d20a7d23b
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term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500
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EGF-like calcium-binding, conserved site [IPR018097] 6 7 2.7801279151250786 0.0054337490064062 1.1703703703703705 2.466666666666667 -0.1373915694631231 0.3902853831950666 1.067180945982341 1.5160051467387146 1.437469353479462 0.3143260829565273 0.0006097953864012 0.1635258499471353 0.3009165941166509 2.4880325513906888e-05 0.0017617577033715
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Syntaxin/epimorphin, conserved site [IPR006012] 5 6 2.6154611807676336 0.0089107049607024 2.592233009708738 5.847087378640777 0.9961908981999794 0.2839139128702306 1.4759357288864456 1.4239341993278547 1.138258151200134 0.2914162845337057 5.737823424793828e-06 0.0607401038440192 0.1180585699575878 2.831336309208378e-07 1.6279070379868977e-05
|
| 4 |
+
Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415] 4 6 2.3712970304034684 0.0177257794677809 1.062730627306273 1.845018450184502 -0.374757291558179 0.2572252390798428 0.9906082579891434 1.2202031996221276 1.9499632968198624 0.2932843562524823 0.0004396452857286 0.0786913117950012 0.0113213926532688 3.906142953800441e-05 9.937036022358197e-05
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interpro_conserved_site/metrics.json
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{
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"type_of_task": "ranksum",
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| 3 |
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"signature_size": 3053,
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| 4 |
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"annotations_size": 278,
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| 5 |
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"title": "Average number of proteins per term",
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| 6 |
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"value": 2.6546762589928057
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}
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interpro_conserved_site/paths.json
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{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C310/C310_val_log2fc"}
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interpro_conserved_site/result.tsv
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Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
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| 2 |
+
EGF-like calcium-binding, conserved site [IPR018097] 0.9326986211424796 2.7801279151250786 0.0054337490064062 0.7801261297149478 0.358232297909642 7 P98164,P48960,P98155,Q07954,P14543,P01130 6
|
| 3 |
+
Syntaxin/epimorphin, conserved site [IPR006012] 0.9209058089924522 2.6154611807676336 0.0089107049607024 0.9169471955817527 0.358232297909642 6 Q13190,O60499,Q9P2W9,O15400,Q13277 5
|
| 4 |
+
Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415] 0.8642904839166773 2.3712970304034684 0.0177257794677809 0.9930704750069768 0.358232297909642 6 P98155,P01130,Q07954,Q92673 4
|
| 5 |
+
Thioredoxin, conserved site [IPR017937] 0.6402152257676984 1.843218735128888 0.0652970805440993 0.9999999929650571 0.3862252849204173 11 Q9H1E5,P07237,Q9H3N1,Q96JJ7 4
|
| 6 |
+
Tetraspanin, conserved site [IPR018503] 0.9426229508196676 1.754605735994299 0.0793267696489621 0.9999999998949652 0.408385962266879 3 O60637,O43657 2
|
| 7 |
+
Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745] 0.9760734185512968 1.6528891983559817 0.0983534158746781 0.9999999999996836 0.4155042840143524 2 P05067 1
|
| 8 |
+
Proteinase inhibitor I2, Kunitz, conserved site [IPR020901] 0.9760734185512968 1.6528891983559817 0.0983534158746781 0.9999999999996836 0.4155042840143524 2 P05067 1
|
| 9 |
+
Amyloidogenic glycoprotein, copper-binding domain conserved site [IPR019744] 0.9760734185512968 1.6528891983559817 0.0983534158746781 0.9999999999996836 0.4155042840143524 2 P05067 1
|
| 10 |
+
Glycoside hydrolase, family 29, conserved site [IPR018526] 0.9731235660439218 1.6406814443418902 0.100863558702005 0.9999999999998542 0.4155042840143524 2 P04066 1
|
| 11 |
+
Sugar transporter, conserved site [IPR005829] 0.9016393442622952 1.5924630353926568 0.1112807024041699 0.9999999999999944 0.4254907589628792 3 Q7L0J3,P11166 2
|
| 12 |
+
C-type lectin, conserved site [IPR018378] 0.9609963946247132 1.5904669582687785 0.1117295877852164 0.999999999999995 0.4254907589628792 2 Q9UBG0 1
|
| 13 |
+
Haem oxygenase conserved site [IPR018207] 0.9472304162569648 1.5334320070824283 0.1251694475248768 1.0 0.4461167488707148 2 P09601 1
|
| 14 |
+
Immunoglobulin/major histocompatibility complex, conserved site [IPR003006] 0.8938053097345231 1.3123238413892118 0.1894108911925376 1.0 0.5318810883992471 2 P04439 1
|
| 15 |
+
DnaJ domain, conserved site [IPR018253] 0.5547508290065581 1.2056802240194788 0.2279408130875582 1.0 0.5614424082739388 9 Q99543,Q96KC8,Q9Y2G8,Q9NVH1 4
|
| 16 |
+
Guanylate kinase, conserved site [IPR020590] 0.6461134798294459 0.9598110738324688 0.3371503079582076 1.0 0.6841444205283338 4 Q00013,Q92796,Q14168 3
|
| 17 |
+
Sterol reductase, conserved site [IPR018083] 0.752540150770258 0.7482110418841568 0.454332871821969 1.0 0.7634675232368939 2 Q14739 1
|
| 18 |
+
Tubulin, conserved site [IPR017975] 0.4886773875943626 0.6033890978648769 0.5462498731287617 1.0 0.8193693809872534 6 P04350,Q9BVA1,Q9BUF5,P07437,P68371 5
|
| 19 |
+
Dynamin, GTPase region, conserved site [IPR019762] 0.6787938380858802 0.4880456841935798 0.6255174825349461 1.0 0.8373055677830434 2 O00429 1
|
| 20 |
+
Intermediate filament protein, conserved site [IPR018039] 0.4354654998607435 0.482451673042578 0.6294851211030794 1.0 0.8373055677830434 8 P48681,P07196,Q16352,P08670 4
|
| 21 |
+
Oxysterol-binding protein, conserved site [IPR018494] 0.5234503115775623 0.4722012286535635 0.6367831628344343 1.0 0.84250233508583 4 Q9BZF1,P22059,Q96SU4 3
|
| 22 |
+
Polyamine biosynthesis domain, conserved site [IPR030373] 0.6430678466076627 0.3779742632553918 0.7054497131406179 1.0 0.8910050015370763 2 P52788 1
|
| 23 |
+
Phosphatidylinositol 3/4-kinase, conserved site [IPR018936] 0.3965825395067981 0.0953799715960803 0.9240130238942564 1.0 0.9900446087990634 4 P42345 1
|
| 24 |
+
Ribosomal protein S5, N-terminal, conserved site [IPR018192] 0.470993117010804 0.0617030289223289 0.9507993278366698 1.0 0.9900446087990634 2 P82675 1
|
| 25 |
+
D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752] 0.4232786885245883 0.050188302504539 0.9599723330566527 1.0 0.9900446087990634 3 Q9GZZ9,O43175 2
|
| 26 |
+
Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326] 0.4414945919370626 0.0425853019233297 0.9660321122274452 1.0 0.9900446087990634 2 P29692 1
|
| 27 |
+
Hexapeptide transferase, conserved site [IPR018357] 0.3952802359881911 0.0258732236649184 0.9793584573149084 1.0 0.9933273624799296 2 Q9Y5P6 1
|
interpro_conserved_site/selections.json
ADDED
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{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Aldose 1-epimerase, conserved site [IPR018052]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Aminotransferase, class IV, conserved site [IPR018300]", "Amyloidogenic glycoprotein, copper-binding domain conserved site [IPR019744]", "Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]", "Anion exchange, conserved site [IPR018241]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "CBX family C-terminal motif [IPR033773]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Copper type II, ascorbate-dependent monooxygenase, histidine-cluster-1 conserved site [IPR020611]", "Copper type II, ascorbate-dependent monooxygenase, histidine-cluster-2 conserved site [IPR014783]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific, conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA mismatch repair, conserved site [IPR014762]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dpy-30 motif [IPR007858]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Endonuclease III-like, conserved site-2 [IPR004036]", "Endonuclease III-like, iron-sulphur cluster loop motif [IPR003651]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Ependymin, conserved site [IPR018224]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "Fibrillarin, conserved site [IPR020813]", "Fork head domain conserved site 2 [IPR030456]", "Fork head domain conserved site1 [IPR018122]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GPCR, family 2, secretin-like, conserved site [IPR017983]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glutathione peroxidase conserved site [IPR029760]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 2, conserved site [IPR023230]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Heavy-metal-associated, conserved site [IPR017969]", "Helix-hairpin-helix motif [IPR000445]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Integrin alpha chain, C-terminal cytoplasmic region, conserved site [IPR018184]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "Molybdenum cofactor biosynthesis, conserved site [IPR008284]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NADH:ubiquinone oxidoreductase, subunit 1, conserved site [IPR018086]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site [IPR023058]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Rel homology domain, conserved site [IPR030492]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P, conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubby, C-terminal, conserved site [IPR018066]", "Tubulin, conserved site [IPR017975]", "Tyrosine-protein kinase, receptor class II, conserved site [IPR002011]", "Tyrosine-protein kinase, receptor class V, conserved site [IPR001426]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]"], "available_proteins": ["AAAS", "AAMP", "ABCB1", "ABCB7", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADSB", "ACAT1", "ACAT2", "ACBD5", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADGRE5", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK4", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1M1", "AP2M1", "AP2S1", "AP3M1", "AP3S1", "APEX1", "APLP2", "APP", "ARIH2", "ATAD1", "ATP5C1", "ATP5O", "ATP7A", "BAG6", "BAX", "BAZ1A", "BAZ1B", "BAZ2A", "BCAT1", "BCAT2", "BCS1L", "BDH2", "BOP1", "BPNT1", "BRCA1", "BRD2", "BRD4", "BUD31", "CAD", "CALR", "CANX", "CAP1", "CAP2", "CAPZA1", "CAPZA2", "CAPZB", "CBL", "CBR1", "CBX1", "CBX3", "CBX4", "CBX5", "CBX8", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD320", "CDC40", "CDH2", "CDKAL1", "CDYL", "CECR2", "CETN2", "CHAF1B", "CHD1", "CHD1L", "CHD3", "CHD4", "CLGN", "CMPK1", "CNDP2", "COLEC12", "COPA", "COPZ1", "CORO1B", "CORO1C", "CORO7", "CPOX", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CYP51A1", "DCAF7", "DCP2", "DCPS", "DCXR", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX31", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX6", "DHCR7", "DHFR", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIMT1", "DIS3", "DLG3", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC16", "DNAJC2", "DNAJC21", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DPY30", "DRG1", "DRG2", "DSC1", "DSC2", "DSC3", "DSG2", "DTYMK", "DYNLL1", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4E", "EIF4E2", "ENO1", "ENO2", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPRS", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FBL", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FOXC1", "FUCA1", "FUCA2", "GAA", "GALK1", "GALM", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GLA", "GLB1", "GLO1", "GMPPA", "GMPPB", "GNPDA1", "GNS", "GPHN", "GPI", "GPX8", "GRHPR", "GRWD1", "GSPT1", "GUSB", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HIBADH", "HINT2", "HLA-A", "HLA-B", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMOX1", "HMOX2", "HSD17B10", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IGF1R", "ILVBL", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INTS12", "IQGAP1", "IQGAP2", "ITGAV", "IVD", "KDM2A", "KDSR", "KIF11", "KIF18B", "KIF1A", "KIF1B", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFC1", "LAMP1", "LARS", "LARS2", "LBR", "LDLR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRP1", "LRP2", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK3", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME1", "ME2", "MGST2", "MID1", "MIF", "MPI", "MPP1", "MPP2", "MPP6", "MPST", "MRC2", "MRPL3", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "ND1", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFV1", "NEFL", "NEFM", "NES", "NF1", "NID1", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NSD1", "NSD2", "NSF", "NTHL1", "NUBP2", "NUDT1", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL11", "OSBPL8", "OSBPL9", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PAM", "PBRM1", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA6", "PEBP1", "PEPD", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHF14", "PHF3", "PHGDH", "PHIP", "PI4KB", "PIK3C2A", "PIN1", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS3", "PMS1", "PNP", "POLA1", "POLD1", "POLR1B", "POLR1C", "POLR2B", "POLR2C", "POLR2E", "PPIB", "PPID", "PPIF", "PPIH", "PPIL1", "PPIL3", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PUS7", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "QDPR", "RACK1", "RAE1", "RANBP2", "RARS", "RARS2", "RCL1", "RDH13", "RDX", "RECQL5", "REL", "RNF14", "RNF2", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS24", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "RSF1", "S100A10", "S100A11", "SART1", "SBDS", "SCAF11", "SCD", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB1", "SERPINB6", "SERPINB8", "SERPINH1", "SLC1A5", "SLC27A4", "SLC2A1", "SLC2A4", "SLC4A2", "SLIT2", "SMARCA4", "SMS", "SMU1", "SNRNP40", "SNU13", "SORD", "SORL1", "SPATA5", "SPATA5L1", "SPTBN1", "SRCAP", "SRM", "STAM", "STMN1", "STRN", "STX10", "STX12", "STX18", "STX3", "STX5", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SV2A", "SYNE2", "TAP1", "TBL1XR1", "TBL3", "TCP1", "THOC6", "TK1", "TLN1", "TMX1", "TMX3", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRIM21", "TRIM25", "TRIM28", "TRIM33", "TRIP13", "TRMT11", "TSFM", "TSPAN10", "TSPAN3", "TSPAN6", "TST", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUFM", "TULP3", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UBA5", "UHRF1", "USP10", "USP11", "USP14", "USP24", "USP28", "USP33", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VAT1", "VCL", "VCP", "VIM", "VLDLR", "VPS4A", "VPS4B", "WARS", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR36", "WDR41", "WDR5", "WDR61", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZMYND8"], "leading_proteins": ["ADGRE5", "APP", "DLG3", "DNAJC1", "DNAJC11", "DNAJC16", "DNAJC2", "DNM1L", "EEF1D", "FUCA1", "GMPPB", "HLA-A", "HMOX1", "INA", "LBR", "LDLR", "LRP1", "LRP2", "MPP1", "MPP2", "MRC2", "MRPS5", "MTOR", "NEFL", "NES", "NID1", "OSBP", "OSBPL8", "OSBPL9", "P4HB", "PHGDH", "SLC2A1", "SMS", "SORL1", "STX10", "STX18", "STX3", "STX5", "STX7", "SV2A", "TMX1", "TMX3", "TMX4", "TSPAN3", "TSPAN6", "TUBB", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "UBA5", "VIM", "VLDLR"]}
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{"0": "Immunoglobulin-like domain [IPR007110]", "1": "EGF-like domain [IPR000742]", "2": "EGF-like calcium-binding domain [IPR001881]", "3": "Immunoglobulin subtype [IPR003599]", "4": "Immunoglobulin subtype 2 [IPR003598]", "5": "Target SNARE coiled-coil homology domain [IPR000727]", "6": "EF-hand domain [IPR002048]"}
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{"0": "Immunoglobulin-like domain [IPR007110]", "1": "EGF-like domain [IPR000742]", "2": "EGF-like calcium-binding domain [IPR001881]", "3": "Immunoglobulin subtype [IPR003599]", "4": "Immunoglobulin subtype 2 [IPR003598]", "5": "Target SNARE coiled-coil homology domain [IPR000727]", "6": "EF-hand domain [IPR002048]", "7": "Small GTP-binding protein domain [IPR005225]", "8": "Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]", "9": "Tubulin/FtsZ, GTPase domain [IPR003008]", "10": "Guanylate kinase/L-type calcium channel beta subunit [IPR008145]", "11": "Guanylate kinase-like domain [IPR008144]", "12": "AP complex, mu/sigma subunit [IPR022775]", "13": "Thioredoxin domain [IPR013766]", "14": "DnaJ domain [IPR001623]"}
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