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interpro_active_site/advanced/idx2term.json

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+{}

interpro_active_site/basic/idx2term.json

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+{}

interpro_active_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:716109e80c45454fbf5ca2e523608da21ca4b158c11fd8c045b052cff5858889
+size 72367

interpro_active_site/df_merge.tsv

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+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_active_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2772,
+    "annotations_size": 56,
+    "title": "Average number of proteins per term",
+    "value": 2.392857142857143
+}

interpro_active_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C321/C321_val_log2fc"}

interpro_active_site/result.tsv

@@ -0,0 +1,6 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Malate dehydrogenase, active site [IPR001252]	0.6400722021660608	1.0861898390742553	0.2773950117733927	0.999999987455496	0.3788809916904877	2	P40925	1
+Peptidase family C14A, cysteine active site [IPR033139]	0.6417600462103835	0.5916315512063265	0.5540973412940866	1.0	0.6602010874993373	3	P42574	1
+Peptidase family C14A, His active site [IPR016129]	0.6417600462103835	0.5916315512063265	0.5540973412940866	1.0	0.6602010874993373	3	P42574	1
+Thiolase, active site [IPR020610]	0.3981854020771604	0.2211029516240134	0.8250122720691886	1.0	0.8884747545360492	5	P24752,P55084	2
+Ubiquitin-conjugating enzyme, active site [IPR023313]	0.3753907232019778	0.1710025547022331	0.8642217568231372	1.0	0.9131399694735036	5	Q16763	1

interpro_active_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["ATP synthase, F0 complex, subunit A, active site [IPR023011]", "ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenosine/AMP deaminase active site [IPR006650]", "Adenylosuccinate synthase,  active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycoside hydrolase, family 2, active site [IPR023232]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Peptidase family C14A, His active site [IPR016129]", "Peptidase family C14A, cysteine active site [IPR033139]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]", "Uracil-DNA glycosylase, active site [IPR018085]"], "available_proteins": ["ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADA", "ADSS", "AKT1", "AKT2", "APEH", "ATP5A1", "ATP5B", "ATP6", "ATP6V1A", "ATP6V1B2", "BLMH", "CAPN1", "CASP2", "CASP3", "CASP6", "CDK1", "CDK13", "CDK2", "CDK4", "CDK6", "CHEK2", "CHUK", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CTSA", "CTSB", "CTSC", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLUD1", "GSR", "GUSB", "HADHB", "HMGCL", "HMGCS1", "IGF1R", "LDHA", "LDHB", "LONP1", "MAP2K1", "MAP2K2", "MAP3K7", "MAPK1", "MAPK3", "MARK2", "MDH1", "MDH2", "MTMR6", "NEK9", "NME1", "NME2", "PAK2", "PASK", "PBK", "PGAM1", "PKM", "PKMYT1", "PKN2", "PLK1", "PREP", "PRKAA1", "PRKACA", "PRPF4B", "PTK7", "PTPN1", "PTPN11", "RNASET2", "ROCK2", "RPS6KA1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SUCLG1", "TALDO1", "TOP1", "TPI1", "TPP2", "TTK", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "UMPS", "UNG", "VRK1"], "leading_proteins": ["ACAT1", "CASP3", "HADHB", "MDH1", "UBE2S"]}

interpro_binding_site/advanced/idx2term.json

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+{}

interpro_binding_site/basic/idx2term.json

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+{"0": "Protein kinase, ATP binding site [IPR017441]"}

interpro_binding_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:d85363c709bc65c6a018a34558535d74c4e19bf5c94c25108222f0e5ef4019fe
+size 64927

interpro_binding_site/df_merge.tsv

@@ -0,0 +1 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_binding_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2772,
+    "annotations_size": 28,
+    "title": "Average number of proteins per term",
+    "value": 4.285714285714286
+}

interpro_binding_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C321/C321_val_log2fc"}

interpro_binding_site/result.tsv

@@ -0,0 +1,5 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Protein kinase, ATP binding site [IPR017441]	0.4029274129850068	1.149894884646663	0.2501871680183836	0.9996847316908832	0.4120729826185141	36	O43318,O95747,Q14004,P31749,Q7KZI7,P31751,Q99640,P36507,Q13043	9
+Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]	0.6451263537906096	1.1093610108724934	0.2672744749855842	0.9998346679764416	0.4157602944220198	2	P34897	1
+PPM-type phosphatase, divalent cation binding [IPR000222]	0.7687100860770095	1.0315821668381644	0.3022678980642812	0.9999579966686186	0.4231750572899937	3	P49593	1
+Beta tubulin, autoregulation binding site [IPR013838]	0.3559066808906926	0.145837185258275	0.884049920122407	1.0	0.884049920122407	6	P68371,P04350,Q13885	3

interpro_binding_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]"], "available_proteins": ["ACACA", "ACO2", "ACTN1", "ACTN4", "ADSS", "AKT1", "AKT2", "APEX1", "ASPM", "BPNT1", "CALU", "CAPN1", "CDK1", "CDK13", "CDK2", "CDK4", "CDK6", "CHUK", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A2", "CYB5B", "DLAT", "DLST", "DST", "EHD1", "EIF2AK2", "FKBP10", "FKBP14", "FKBP7", "FKBP9", "GCAT", "GOT1", "GOT2", "GPD2", "HK1", "HK2", "IDE", "IGF1R", "ILKAP", "IQGAP1", "LETM1", "MACF1", "MAP2K1", "MAP2K2", "MAP3K7", "MAPK1", "MAPK14", "MAPK3", "MARK2", "MCCC1", "MICU1", "MYH10", "MYH9", "MYO1B", "MYO1C", "MYO1D", "NFS1", "NRDC", "NUCB1", "NUCB2", "OXSR1", "PA2G4", "PAK2", "PASK", "PC", "PCCA", "PDCD6", "PEF1", "PGD", "PKMYT1", "PKN2", "PLCG1", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1F", "PPM1G", "PRKAA1", "PRKACA", "PRKCSH", "PSAT1", "RAB18", "RCN1", "RCN2", "RHOT1", "RHOT2", "ROCK2", "RPS6KA1", "RPS6KA3", "S100A11", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "STK4", "TKT", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "UBE3C", "UQCRC2", "VRK1"], "leading_proteins": ["AKT1", "AKT2", "CDK13", "MAP2K2", "MAP3K7", "MARK2", "OXSR1", "PKMYT1", "PPM1F", "SHMT2", "STK4", "TUBB2A", "TUBB4A", "TUBB4B"]}

interpro_conserved_site/advanced/idx2term.json

@@ -0,0 +1 @@
+{}

interpro_conserved_site/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "ABC transporter-like, conserved site [IPR017871]", "1": "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]"}

interpro_conserved_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:8a261b921526f66b7ffb888c644a058b1540b3794833f05d4e1f6250262cb421
+size 113686

interpro_conserved_site/df_merge.tsv

@@ -0,0 +1 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_conserved_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2772,
+    "annotations_size": 257,
+    "title": "Average number of proteins per term",
+    "value": 2.5525291828793772
+}

interpro_conserved_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C321/C321_val_log2fc"}

interpro_conserved_site/result.tsv

@@ -0,0 +1,32 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Haem oxygenase conserved site [IPR018207]	0.9610108303249096	2.5395644357449414	0.0110990598030693	0.943210639548242	0.0331681205742886	2	P30519	1
+ABC transporter-like, conserved site [IPR017871]	0.7042949086679792	1.7802510807136305	0.0750348791255306	0.999999998031132	0.1460906358731922	10	O75027,P33527,Q8NE71,O15439,Q9NRK6	5
+Ribosomal protein S5, N-terminal, conserved site [IPR018192]	0.7530685920577591	1.6087708690700924	0.107666452901828	0.999999999999807	0.1919935097612044	2	P82675	1
+Cyclic nucleotide-binding, conserved site [IPR018488]	0.6653429602888048	1.202451344936469	0.2291887062758046	1.0	0.3257010270244915	2	P10644	1
+Ubiquitin interacting motif [IPR003903]	0.8153200359373043	1.2019451755168595	0.2293847700055757	1.0	0.3257010270244915	3	Q92783	1
+Serpin, conserved site [IPR023795]	0.6628158844765306	1.1907854679883183	0.2337378151930698	1.0	0.3300583434319721	2	P50454	1
+Ribonuclease II/R, conserved site [IPR022966]	0.6523465703971079	1.1425399002050438	0.2532296707327797	1.0	0.353695790099589	2	Q8IYB7	1
+Thioredoxin, conserved site [IPR017937]	0.5181409439911643	0.9820752692777992	0.3260627680632963	1.0	0.4387336722108229	11	Q9H1E5	1
+Ubiquitin-activating enzyme E1, conserved site [IPR018074]	0.6101083032490929	0.9500290780315024	0.3420974777465431	1.0	0.4579117280253207	2	Q9UBT2	1
+ATPase, AAA-type, conserved site [IPR003960]	0.4451128909055655	0.911514602503796	0.3620242951625636	1.0	0.4820738023667298	16	Q9Y276,Q8NBU5,Q96TA2	3
+Phosphorylase pyridoxal-phosphate attachment site [IPR035090]	0.588447653429598	0.8533755857301134	0.3934510559916129	1.0	0.5055846069492226	2	P06737	1
+Kinesin motor domain, conserved site [IPR019821]	0.4898154818122675	0.7715143972685866	0.4404020920129725	1.0	0.5575533874252904	10	O00139,Q02241,Q99661,Q12756	4
+Actin, conserved site [IPR004001]	0.5588447653429549	0.7248093471845323	0.4685690006378076	1.0	0.5874255276288612	2	P61163	1
+DNA-directed DNA polymerase, family B, conserved site [IPR017964]	0.5534296028880812	0.701845211841229	0.482775699683486	1.0	0.602297838925514	2	P09884	1
+S100/Calbindin-D9k, conserved site [IPR001751]	0.5509025270758068	0.691195991431694	0.4894423826426699	1.0	0.6058122168780344	2	P31949	1
+Ribosomal protein L3, conserved site [IPR019926]	0.5490974729241822	0.6836165908114392	0.4942173054267214	1.0	0.6077217583476909	2	P09001	1
+DnaJ domain, conserved site [IPR018253]	0.4777571891341547	0.6550250033183741	0.5124516560355759	1.0	0.624170974413	9	Q96EY1	1
+Hexapeptide transferase, conserved site [IPR018357]	0.5097472924187668	0.524938537692611	0.5996259181655825	1.0	0.7134438007803459	2	Q96IJ6	1
+Intermediate filament protein, conserved site [IPR018039]	0.4573107518890721	0.520263008743467	0.6028802744750676	1.0	0.7140102789866009	8	P07196	1
+Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]	0.6037320574317578	0.4737110856744929	0.6357059470139355	1.0	0.746011088504938	3	Q96I99	1
+GHMP kinase, ATP-binding, conserved site [IPR006203]	0.4693140794223762	0.378648865792321	0.7049486297706093	1.0	0.8088026689778866	2	Q03426	1
+Calreticulin/calnexin, conserved site [IPR018124]	0.5505182581020889	0.3267844777327577	0.7438309004399746	1.0	0.8347796568256483	3	O14967	1
+Heat shock protein Hsp90, conserved site [IPR019805]	0.5433563873416648	0.3089425964786453	0.7573651933842296	1.0	0.8462732813032477	3	P08238	1
+Purine phosphorylase, family 2, conserved site [IPR018099]	0.4281588447653369	0.2530490461269676	0.8002303128919976	1.0	0.8761336516004772	2	P00491	1
+Ribosomal protein L30, conserved site [IPR018038]	0.4162454873646136	0.221839297069003	0.8244389869061615	1.0	0.8940118971936012	2	P18124	1
+DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]	0.3370773249303117	0.214628895223296	0.8300566637651585	1.0	0.89632169154473	11	Q9H2U1,Q86WJ1,Q7L2E3,Q7Z478,P18074	5
+Proteasome beta-type subunit, conserved site [IPR016050]	0.3549635184846298	0.1907056497148436	0.848756212099288	1.0	0.9088764437896542	8	P49721	1
+HMG box A DNA-binding domain, conserved site [IPR017967]	0.4658721560130068	0.1508762129099018	0.8800733650102817	1.0	0.9307223599087509	3	P09429,O15347	2
+Tubulin, conserved site [IPR017975]	0.3559066808906926	0.145837185258275	0.884049920122407	1.0	0.9307223599087509	6	P68371,P04350,Q13885	3
+Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]	0.3936439147706707	0.0646998450709367	0.9484129861812453	1.0	0.9781646636001068	3	P42345,O00443	2
+Cullin, conserved site [IPR016157]	0.2580411998554394	0.028944899682249	0.9769085358404488	1.0	0.9923537300829854	5	Q13616,Q93034,Q13617,Q13618	4

interpro_conserved_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Aldose 1-epimerase, conserved site [IPR018052]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Aminotransferase, class IV, conserved site [IPR018300]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Bromodomain, conserved site [IPR018359]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific,  conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "Fibrillarin, conserved site [IPR020813]", "Fork head domain conserved site 2 [IPR030456]", "Fork head domain conserved site1 [IPR018122]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 2, conserved site [IPR023230]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Heavy-metal-associated, conserved site [IPR017969]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M22, conserved site [IPR017860]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site [IPR023058]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Pyridoxamine 5'-phosphate oxidase, conserved site [IPR019740]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P,  conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "Tyrosine-protein kinase, receptor class II, conserved site [IPR002011]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]"], "available_proteins": ["AAAS", "AAMP", "ABCB1", "ABCB10", "ABCB7", "ABCC1", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK4", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1M1", "AP2M1", "AP3M1", "APEX1", "ARHGEF7", "ATAD1", "ATP5C1", "ATP5O", "ATP7B", "BAG6", "BAK1", "BAX", "BAZ1A", "BAZ1B", "BCAT2", "BCS1L", "BOP1", "BPNT1", "BRD2", "BUD31", "CAD", "CALR", "CANX", "CAP1", "CAPZA1", "CAPZB", "CASK", "CBR1", "CBX1", "CBX3", "CBX5", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD81", "CDKAL1", "CHAF1B", "CHD1", "CHD1L", "CHD4", "CLGN", "CMPK1", "CNDP2", "COPA", "COPZ1", "CORO1C", "CPOX", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CYP51A1", "DCAF13", "DCAF7", "DCPS", "DCXR", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX5", "DDX51", "DDX54", "DDX55", "DDX6", "DHFR", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX40", "DHX8", "DHX9", "DIDO1", "DIS3", "DIS3L2", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC9", "DNM1", "DNM1L", "DNM2", "DNMT1", "DRG1", "DRG2", "DSG2", "DST", "DTL", "DTYMK", "DYNLL1", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EIF3I", "EIF4A1", "EIF4A3", "EIF4E", "ENO1", "EPB41", "EPB41L2", "EPB41L3", "EPRS", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FBL", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FOXC1", "FUCA2", "GAA", "GALK1", "GALM", "GANAB", "GART", "GCDH", "GEMIN5", "GFM1", "GLA", "GLB1", "GLO1", "GMPPA", "GMPPB", "GNPDA1", "GNS", "GPI", "GRHPR", "GRWD1", "GSPT1", "GTF3C2", "GUSB", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HGS", "HIBADH", "HINT2", "HLA-A", "HLA-B", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMOX1", "HMOX2", "HSD17B10", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IGF1R", "ILVBL", "IMPAD1", "IMPDH2", "INA", "IQGAP1", "IVD", "KDSR", "KIF11", "KIF1A", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "LAMP1", "LARS", "LARS2", "LBR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK14", "MAPK3", "MARS", "MAT2A", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME1", "ME2", "MGST2", "MID1", "MIF", "MPI", "MPP2", "MPP6", "MPST", "MRPL3", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "MVK", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFV1", "NEFL", "NEFM", "NES", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NSD2", "NSF", "NSUN6", "NUBP2", "NUBPL", "NUDT1", "NUDT12", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL8", "OSBPL9", "OSGEP", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PBRM1", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PEBP1", "PEPD", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHF2", "PHF3", "PHGDH", "PHIP", "PIK3C2A", "PIN1", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PNP", "PNPLA6", "PNPO", "POLA1", "POLD1", "POLR1B", "POLR1C", "POLR2B", "POLR2E", "PPIB", "PPID", "PPIF", "PPIH", "PPIL1", "PPIL3", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PUS7", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "QDPR", "RACK1", "RAE1", "RANBP2", "RARS", "RASA1", "RCL1", "RDH13", "RDX", "RIDA", "RNF114", "RNF14", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS24", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "RSF1", "RTN4IP1", "S100A10", "S100A11", "SART1", "SBDS", "SCD", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB6", "SERPINH1", "SLC1A5", "SLC27A4", "SMARCA4", "SMS", "SMU1", "SNRNP40", "SNU13", "SORD", "SPATA5L1", "SPTBN1", "SPTBN2", "SRCAP", "SRM", "STAM", "STMN1", "STRN", "STX10", "STX12", "STX17", "STX18", "STX4", "STX5", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SV2A", "SYNE2", "TBL3", "TCP1", "TK1", "TLN1", "TMX1", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRIM21", "TRIM25", "TRIM27", "TRIM28", "TRIP13", "TRMT11", "TSFM", "TSPAN3", "TSPAN6", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUFM", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UHRF1", "USP10", "USP11", "USP14", "USP19", "USP28", "USP33", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VARS2", "VAT1", "VCL", "VCP", "VIM", "VPS4A", "WARS", "WDHD1", "WDR1", "WDR18", "WDR3", "WDR36", "WDR41", "WDR5", "WDR61", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2"], "leading_proteins": ["ABCB10", "ABCB7", "ABCC1", "ABCC4", "ABCF1", "ACTR1A", "ATAD1", "BCS1L", "CHD1L", "CLGN", "CUL1", "CUL2", "CUL3", "CUL5", "DHX29", "DHX30", "DHX36", "DIS3L2", "DNAJA3", "ERCC2", "GMPPA", "HMGB1", "HMGB3", "HMOX2", "HSP90AB1", "KIF1A", "KIF23", "KIF2A", "KIF2C", "MRPL3", "MRPS5", "MTOR", "MVK", "NEFL", "PIK3C2A", "PNP", "POLA1", "PRKAR1A", "PSMB2", "PYGL", "RPL7", "S100A11", "SERPINH1", "STAM", "SUCLG2", "TMX4", "TUBB2A", "TUBB4A", "TUBB4B", "UBA2", "YME1L1"]}

interpro_domain/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "AAA+ ATPase domain [IPR003593]"}

interpro_domain/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "AAA+ ATPase domain [IPR003593]", "1": "ABC transporter-like, ATP-binding domain [IPR003439]", "2": "Linker histone H1/H5, domain H15 [IPR005818]", "3": "DEAD/DEAH box helicase domain [IPR011545]", "4": "GTP binding domain [IPR006073]", "5": "Protein kinase domain [IPR000719]", "6": "K Homology domain, type 1 [IPR004088]", "7": "Pleckstrin homology domain [IPR001849]", "8": "Helicase superfamily 1/2, ATP-binding domain [IPR014001]", "9": "K Homology domain [IPR004087]", "10": "Helicase, C-terminal [IPR001650]", "11": "SNF2, N-terminal [IPR000330]", "12": "EF-hand domain [IPR002048]", "13": "Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) [IPR002314]", "14": "Cullin, N-terminal [IPR001373]"}

interpro_domain/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:cf0384c92bc27a975991d5d1f9eb4371f3c07e894dc836a02cbc745d387f0a8c
+size 595767

interpro_domain/df_merge.tsv

@@ -0,0 +1,2 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+AAA+ ATPase domain [IPR003593]	11	48	1.998367599311185	0.0456768216560432	15.315533980582524	53.91504854368932	-0.301482547874648	0.7101193728807252	8.066919832789411	5.471467628283315	0.5679404146055311	0.2838562818290112	1.0	0.0762203496734667	0.0602097240353476	0.0784860492089058	0.0062982805053085

interpro_domain/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2772,
+    "annotations_size": 2334,
+    "title": "Average number of proteins per term",
+    "value": 2.0972579263067694
+}

interpro_domain/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C321/C321_val_log2fc"}

interpro_domain/result.tsv

@@ -0,0 +1,193 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Cytosolic fatty-acid binding [IPR000463]	0.9711191335740068	2.5829405517627073	0.0097962201343093	0.9999999998950048	0.0266795540180607	2	P09455	1
+Lipocalin/cytosolic fatty-acid binding domain [IPR000566]	0.9711191335740068	2.5829405517627073	0.0097962201343093	0.9999999998950048	0.0266795540180607	2	P09455	1
+Protein Kinase B, pleckstrin homology domain [IPR039026]	0.9259927797833928	2.3878488487723786	0.0169473102687207	1.0	0.0407783733682415	2	P31749	1
+Vicinal oxygen chelate (VOC) domain [IPR037523]	0.9180505415162444	2.353129013801502	0.0186161738159791	1.0	0.0431053072286659	2	Q9HC38	1
+NECAP, PHear domain [IPR012466]	0.9144404332129954	2.337309761523041	0.0194230833466231	1.0	0.0444010543888524	2	Q8NC96	1
+Kinesin-like [IPR022164]	0.8938628158844761	2.2466969584022136	0.0246594007761378	1.0	0.0532424064861292	2	Q9Y3P9	1
+GCF, C-terminal [IPR022783]	0.8924187725631765	2.240310129019991	0.0250707961231952	1.0	0.0537823880069281	2	P16383	1
+Acyl-CoA oxidase, C-terminal [IPR002655]	0.8826714801444038	2.1971041980219552	0.0280130053747811	1.0	0.0584292712642887	2	O15254	1
+SGNH hydrolase-type esterase domain [IPR013830]	0.8581227436823092	2.0875718456703427	0.0368364738857214	1.0	0.0719467197065052	2	Q15102	1
+Arfaptin homology (AH) domain [IPR010504]	0.8570397111913339	2.082716422831926	0.0372770795878114	1.0	0.0725039197982932	2	P53365	1
+AAA+ ATPase domain [IPR003593]	0.4795288827127181	1.9983675993111851	0.0456768216560432	1.0	0.0844678534812224	48	Q9NUQ8,Q9Y276,Q8NBU5,O75027,Q9NVI7,P08240,P33527,Q96TA2,Q8NE71,O15439,Q9NRK6	11
+Potassium channel tetramerisation-type BTB domain [IPR003131]	0.822382671480143	1.926364016351504	0.0540589372025688	1.0	0.0970565841775351	2	Q9NXV2	1
+Gamma tubulin complex component protein, N-terminal [IPR041470]	0.8212996389891682	1.9214486289068131	0.0546751728631615	1.0	0.0977868608908959	2	Q96CW5	1
+Gamma tubulin complex component, C-terminal [IPR040457]	0.8212996389891682	1.9214486289068131	0.0546751728631615	1.0	0.0977868608908959	2	Q96CW5	1
+Tim10-like [IPR004217]	0.8061371841155216	1.8524588006595024	0.063959968418191	1.0	0.1102949135385768	2	Q9Y5L4	1
+SLIDE domain [IPR015195]	0.8025270758122725	1.835986239916477	0.0663596917529809	1.0	0.1138012641818203	2	P28370	1
+ISWI, HAND domain [IPR015194]	0.8025270758122725	1.835986239916477	0.0663596917529809	1.0	0.1138012641818203	2	P28370	1
+ABC transporter-like, ATP-binding domain [IPR003439]	0.7042949086679792	1.7802510807136305	0.0750348791255306	1.0	0.1252751343406438	10	O75027,P33527,Q8NE71,O15439,Q9NRK6	5
+ABC transporter type 1, transmembrane domain [IPR011527]	0.7933670416501055	1.7434496024844044	0.0812551103036209	1.0	0.1329007900831474	6	P33527,O75027	2
+Diaphanous autoregulatory (DAD) domain [IPR014767]	0.7743682310469291	1.706944016053614	0.0878324585447996	1.0	0.1417710637922284	2	Q9NSV4	1
+Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain [IPR019564]	0.9506233729254324	1.69942286946123	0.0892395359717892	1.0	0.1435458834997629	3	Q13505	1
+Metaxin, glutathione S-transferase domain [IPR033468]	0.9506233729254324	1.69942286946123	0.0892395359717892	1.0	0.1435458834997629	3	Q13505	1
+Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain [IPR008152]	0.781562520487384	1.617914330994365	0.1056810613730578	1.0	0.1624377805551956	5	Q10567	1
+Ribosomal protein S5, C-terminal [IPR005324]	0.7530685920577591	1.6087708690700924	0.107666452901828	1.0	0.1645667983450339	2	P82675	1
+Ribosomal protein S5, N-terminal [IPR013810]	0.7530685920577591	1.6087708690700924	0.107666452901828	1.0	0.1645667983450339	2	P82675	1
+JAB1/MPN/MOV34 metalloenzyme domain [IPR000555]	0.7072097033197038	1.5941899850642858	0.1108934889546597	1.0	0.1679593791175703	8	O00487	1
+GMP phosphodiesterase, delta subunit [IPR008015]	0.9208085070526096	1.5903084808660164	0.1117652879074793	1.0	0.1686279636096631	3	A6NIH7	1
+Ribosome receptor lysine/proline rich [IPR007794]	0.7469314079422357	1.580411293584169	0.114012706896583	1.0	0.1712391620956401	2	Q86UP2	1
+Translation initiation factor IF- 2, domain 3 [IPR023115]	0.7382671480144377	1.5403294840734298	0.1234800603826415	1.0	0.181831205636016	2	P46199	1
+Transketolase, C-terminal domain [IPR033248]	0.7342960288808636	1.5219434771511942	0.1280232439996198	1.0	0.1872219620896696	2	P29401	1
+CARD domain [IPR001315]	0.7324909747292391	1.513583440689905	0.1301315236290681	1.0	0.1892379913708691	2	O95999	1
+Circularly permuted (CP)-type guanine nucleotide-binding (G) domain [IPR030378]	0.7530256882277554	1.5046139599714383	0.1324233551050704	1.0	0.1916156917639394	5	Q9NVN8	1
+Tim44-like domain [IPR007379]	0.7184115523465673	1.448328398195435	0.1475252291576025	1.0	0.2096978592288942	2	Q9BRJ2	1
+LEM-like domain [IPR013146]	0.7148014440433182	1.4315866860829076	0.1522621421622563	1.0	0.2151209684059964	2	P42166	1
+Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal [IPR007886]	0.7043321299638956	1.3830267334430837	0.1666566689518829	1.0	0.230846685657979	2	Q13423	1
+Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain [IPR007698]	0.7043321299638956	1.3830267334430837	0.1666566689518829	1.0	0.230846685657979	2	Q13423	1
+ARHGEF1-like, PH domain [IPR041020]	0.7032490974729209	1.3780031788030258	0.1682023066990856	1.0	0.2325735686230248	2	Q92974	1
+MPN domain [IPR037518]	0.5891710054087531	1.332296755753508	0.1827626928018726	1.0	0.2474283312721634	11	O00487	1
+Linker histone H1/H5, domain H15 [IPR005818]	0.6872740419378363	1.3104499469955415	0.1900436662928899	1.0	0.2553609194747295	6	P10412,P16403,P16402,Q92522,P07305	5
+DEAD/DEAH box helicase domain [IPR011545]	0.4082987837666793	1.3062787110670468	0.1914577940745054	1.0	0.2569652049280597	41	O00148,Q9H2U1,O94761,Q8NHQ9,Q86XP3	5
+G-protein, beta subunit [IPR001632]	0.6819494584837511	1.2792611227320991	0.2008051181443635	1.0	0.266261099459869	2	Q9NVX2	1
+GTP binding domain [IPR006073]	0.5739481046023029	1.2570521100320031	0.2087347667993651	1.0	0.2732400144193596	11	Q13823,Q9NTK5,O75616,P55039,A4D1E9,Q9BZE4,Q9NVN8	7
+60S ribosomal protein L10P, insertion domain [IPR040637]	0.6768953068592023	1.2558610334883706	0.2091663584805632	1.0	0.273651502630961	2	P05388	1
+Intermediate filament head, DNA-binding domain [IPR006821]	0.8075282262361085	1.2347117955250595	0.2169377843623996	1.0	0.2817522315592812	4	P07196	1
+C-CAP/cofactor C-like domain [IPR017901]	0.6703971119133536	1.2258031960990563	0.220272744179246	1.0	0.2849870204625056	2	Q01518	1
+CARP motif [IPR006599]	0.6703971119133536	1.2258031960990563	0.220272744179246	1.0	0.2849870204625056	2	Q01518	1
+cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain [IPR003117]	0.6653429602888048	1.202451344936469	0.2291887062758046	1.0	0.2942389661428647	2	P10644	1
+Serpin domain [IPR023796]	0.6628158844765306	1.1907854679883183	0.2337378151930698	1.0	0.299420450417467	2	P50454	1
+Rpn11/EIF3F, C-terminal [IPR024969]	0.7939576021830093	1.1849173501823924	0.2360501267266135	1.0	0.3017201510295268	4	O00487	1
+BTB/POZ domain [IPR000210]	0.7864884393063565	1.15755277531899	0.2470465905344896	1.0	0.3149135676174215	4	Q96CX2,Q9NXV2,Q9P2R3	3
+Ribonuclease II/R [IPR001900]	0.6523465703971079	1.1425399002050438	0.2532296707327797	1.0	0.3213910013541641	2	Q8IYB7	1
+Dis3-like cold-shock domain 2 [IPR041505]	0.6523465703971079	1.1425399002050438	0.2532296707327797	1.0	0.3213910013541641	2	Q8IYB7	1
+Rrp44-like cold shock domain [IPR033771]	0.6523465703971079	1.1425399002050438	0.2532296707327797	1.0	0.3213910013541641	2	Q8IYB7	1
+Calcineurin-like phosphoesterase domain, ApaH type [IPR004843]	0.6005177643918154	1.1237813157229106	0.2611058097933112	1.0	0.3310271374565933	8	Q6ZT21	1
+Serine hydroxymethyltransferase-like domain [IPR039429]	0.6451263537906096	1.1093610108724934	0.2672744749855842	1.0	0.3362903636745841	2	P34897	1
+Protein kinase C-like, phorbol ester/diacylglycerol-binding domain [IPR002219]	0.7851209823040808	1.0913112282765645	0.2751359587292012	1.0	0.3452512514376106	3	O75116,Q9H0H5	2
+PPM-type phosphatase domain [IPR001932]	0.7616222904676202	1.066767624578038	0.286076781567953	1.0	0.3578259422184364	4	Q9H0C8,P49593	2
+DnaJ domain [IPR001623]	0.4628330555051368	0.9919204461104948	0.3212363343608082	1.0	0.3960726911770346	15	Q13217,Q96EY1	2
+OBG-type guanine nucleotide-binding (G) domain [IPR031167]	0.6245030719190257	0.9910801009933142	0.3216464687612252	1.0	0.396368985263305	5	P55039,Q9NTK5,A4D1E9,Q9BZE4	4
+ERM family, FERM domain C-lobe [IPR041789]	0.7415268134999096	0.9335502387907456	0.3505359440593913	1.0	0.4301529408173604	3	P26038	1
+Macro domain [IPR002589]	0.7408966767429077	0.931294107974076	0.3517014489586096	1.0	0.4313563751284262	3	Q9P0M6	1
+Protein kinase domain [IPR000719]	0.3615475319270103	0.8986386610891125	0.3688451588681687	1.0	0.4504890637353771	45	Q9UHY1,O95747,Q14004,O43318,Q7KZI7,P31749,P31751,Q99640,P36507,Q13043	10
+Complex 1 LYR protein domain [IPR008011]	0.5945848375451217	0.8805727893784312	0.3785490917482301	1.0	0.4596948908118466	2	P56556	1
+Formin, FH3 domain [IPR010472]	0.7261642110161095	0.8787981081182367	0.3795107522574579	1.0	0.4603836256595149	3	Q9NSV4	1
+Formin, GTPase-binding domain [IPR010473]	0.7261642110161095	0.8787981081182367	0.3795107522574579	1.0	0.4603836256595149	3	Q9NSV4	1
+GINS subunit, domain A [IPR021151]	0.7255326832791564	0.8765592928913409	0.3807260577241447	1.0	0.4610209577893638	3	Q9BRX5,Q9Y248	2
+CYRIA/CYRIB, Rac1 binding domain [IPR009828]	0.5913357400721974	0.8661541256710049	0.3864056465188299	1.0	0.4672905590543777	2	Q7L576	1
+Histone H2A, C-terminal domain [IPR032454]	0.7175729702321781	0.8484300111244578	0.3961985349191448	1.0	0.4781423890906329	3	Q9P0M6	1
+Histone H2A/H2B/H3 [IPR007125]	0.7175729702321781	0.8484300111244578	0.3961985349191448	1.0	0.4781423890906329	3	Q9P0M6	1
+Immunoglobulin V-set domain [IPR013106]	0.7068212348573096	0.8107134698290525	0.4175302361679751	1.0	0.500264666948693	3	P78310	1
+Dbl homology (DH) domain [IPR000219]	0.7035030697002491	0.7991436484489934	0.4242071227194337	1.0	0.5077432945780299	3	Q92974,Q14155	2
+K Homology domain, type 1 [IPR004088]	0.3966227176324081	0.7977276433908618	0.4250285584688409	1.0	0.508465738322027	24	Q96PU8,Q8IWZ3,Q15366,Q9Y6M1,Q9Y2W6,P51116	6
+Peptidase M28 [IPR007484]	0.7027807872878183	0.7966297960127466	0.425666067399614	1.0	0.5089675211632679	3	P02786,Q7Z2K6	2
+Kinesin motor domain [IPR001752]	0.4898154818122675	0.7715143972685866	0.4404020920129725	1.0	0.5244380014072846	10	O00139,Q02241,Q99661,Q12756	4
+Proteasomal ATPase OB C-terminal domain [IPR032501]	0.5648925903077657	0.7589785421079761	0.4478653929811118	1.0	0.5322392195610565	5	P62191,P62333	2
+Metastasis-associated protein MTA1, R1 domain [IPR035170]	0.5581227436823052	0.7217363836578994	0.4704565683110948	1.0	0.5556911085213033	2	Q13330	1
+ELM2 domain [IPR000949]	0.5581227436823052	0.7217363836578994	0.4704565683110948	1.0	0.5556911085213033	2	Q13330	1
+Pleckstrin homology domain [IPR001849]	0.3858884501310474	0.7191111876555619	0.4720724146278865	1.0	0.5573176609719207	23	P20936,P31749,Q12756,Q9NQW6,P31751,Q9Y5P4	6
+S100/CaBP-9k-type, calcium binding, subdomain [IPR013787]	0.5509025270758068	0.691195991431694	0.4894423826426699	1.0	0.5757855449032215	2	P31949	1
+Coatomer, WD associated region [IPR006692]	0.5501805054151572	0.6881614811090855	0.4913510974399786	1.0	0.5765779092131272	2	P35606	1
+Vps4 oligomerisation, C-terminal [IPR015415]	0.5498194945848321	0.686645597464062	0.4923060871789522	1.0	0.5774082449626505	2	Q9UN37	1
+Myosin tail [IPR002928]	0.5480144404332075	0.6790800354432587	0.497087151572597	1.0	0.582722959201628	2	P35579	1
+Helicase superfamily 1/2, ATP-binding domain [IPR014001]	0.3305384807897119	0.6696887625462784	0.503056216746324	1.0	0.5885379498175038	55	Q9BQ39,O00148,Q9H2U1,O94761,Q8NHQ9,Q86XP3,Q14527,Q2NKX8,P46100	9
+K Homology domain [IPR004087]	0.3730769088316508	0.647427779572184	0.5173551217310652	1.0	0.6034517012095484	24	Q96PU8,Q8IWZ3,Q15366,Q9Y6M1,Q9Y2W6	5
+Peptidase M3A/M3B catalytic domain [IPR001567]	0.6570982767949234	0.6415865782722872	0.5211416498745343	1.0	0.607261413283656	3	Q99797	1
+TGS [IPR004095]	0.5125928667610686	0.610038960878204	0.541835999043075	1.0	0.6291767272470334	6	P55039,Q9BW92	2
+RNA helicase, DEAD-box type, Q motif [IPR014014]	0.3686720036290074	0.6065718507399136	0.5441350859158356	1.0	0.6315322180644258	22	O00148,Q8NHQ9	2
+Helicase, C-terminal [IPR001650]	0.322523132585005	0.6045184640062328	0.5454989972628961	1.0	0.632486169702732	56	Q9BQ39,O00148,Q9H2U1,O94761,Q8NHQ9,Q86XP3,Q14527,Q2NKX8,P46100	9
+AAA ATPase, AAA+ lid domain [IPR041569]	0.39206691265436	0.5929030166348521	0.5532460590538022	1.0	0.6402293042477218	14	Q8NBU5,Q96TA2	2
+Peptidase C14A, caspase catalytic domain [IPR015917]	0.6417600462103835	0.5916315512063265	0.5540973412940866	1.0	0.6402293042477218	3	P42574	1
+Peptidase C14, caspase non-catalytic subunit p10 [IPR002138]	0.6417600462103835	0.5916315512063265	0.5540973412940866	1.0	0.6402293042477218	3	P42574	1
+Peptidase C14,  p20 domain [IPR001309]	0.6417600462103835	0.5916315512063265	0.5540973412940866	1.0	0.6402293042477218	3	P42574	1
+RNA polymerase Rpb1, domain 1 [IPR007080]	0.6348565752054931	0.569561893595119	0.5689748802551906	1.0	0.6532156274056148	3	O95602	1
+RNA polymerase Rpb1, domain 4 [IPR007083]	0.6348565752054931	0.569561893595119	0.5689748802551906	1.0	0.6532156274056148	3	O95602	1
+RNA polymerase Rpb1, domain 3 [IPR007066]	0.6348565752054931	0.569561893595119	0.5689748802551906	1.0	0.6532156274056148	3	O95602	1
+RNA polymerase, alpha subunit [IPR000722]	0.6348565752054931	0.569561893595119	0.5689748802551906	1.0	0.6532156274056148	3	O95602	1
+RNA polymerase, N-terminal [IPR006592]	0.6348565752054931	0.569561893595119	0.5689748802551906	1.0	0.6532156274056148	3	O95602	1
+RNA polymerase Rpb1, domain 5 [IPR007081]	0.6348565752054931	0.569561893595119	0.5689748802551906	1.0	0.6532156274056148	3	O95602	1
+Amine oxidase [IPR002937]	0.6334416756951973	0.5650723395669551	0.5720245615561799	1.0	0.6547843681570005	3	O60341,Q8NB78	2
+Matrin/U1-C-like, C2H2-type zinc finger [IPR003604]	0.4740316905214509	0.525220477413621	0.5994299312904976	1.0	0.6831393845859479	7	Q5VUA4,Q969S3	2
+UAS [IPR006577]	0.5093862815884416	0.5235489220649486	0.6005923157289934	1.0	0.683936220364224	2	Q96CS3	1
+Importin-beta, N-terminal domain [IPR001494]	0.3781855227908296	0.5233723105422659	0.6007151892659208	1.0	0.683936220364224	14	Q9UI26,O43592	2
+Intermediate filament, rod domain [IPR039008]	0.4573107518890721	0.520263008743467	0.6028802744750676	1.0	0.685398227289239	8	P07196	1
+Transketolase-like, pyrimidine-binding domain [IPR005475]	0.6182737450342984	0.5177076123260307	0.6046622862513589	1.0	0.6870894723031508	3	P29401,P11177	2
+FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]	0.4172044546966511	0.5120467944881842	0.608618259988174	1.0	0.6912481843369334	11	Q9Y680,O95302	2
+Rho GTPase-activating protein domain [IPR000198]	0.4945877376980997	0.5037925567278361	0.614407158761056	1.0	0.6971445350259138	5	Q01968	1
+Electron transfer flavoprotein, alpha/beta-subunit, N-terminal [IPR014730]	0.5007220216606437	0.4906129273724147	0.6237002414131649	1.0	0.7070016335397411	2	P38117	1
+Ubiquitin-activating enzyme E1, FCCH domain [IPR032418]	0.4989169675090191	0.4838545128901917	0.6284891242953294	1.0	0.7110487717427527	2	P22314	1
+Ubiquitin-activating enzyme, SCCH domain [IPR019572]	0.4989169675090191	0.4838545128901917	0.6284891242953294	1.0	0.7110487717427527	2	P22314	1
+Ubiquitin-activating enzyme E1, C-terminal [IPR018965]	0.4989169675090191	0.4838545128901917	0.6284891242953294	1.0	0.7110487717427527	2	P22314	1
+Ubiquitin-activating enzyme E1, four-helix bundle [IPR032420]	0.4989169675090191	0.4838545128901917	0.6284891242953294	1.0	0.7110487717427527	2	P22314	1
+Heat shock protein Hsp90, N-terminal [IPR020575]	0.5868803853317258	0.4722954870277888	0.6367158911733246	1.0	0.7196585423721742	4	Q12931,P08238	2
+CBS domain [IPR000644]	0.4751624437313194	0.4391321040584267	0.660565818068334	1.0	0.7401635234620699	5	Q8NE01	1
+Clathrin/coatomer adaptor, adaptin-like, N-terminal [IPR002553]	0.4062676045356006	0.4167675395270411	0.6768484475625638	1.0	0.7573174863907114	10	Q10567	1
+Immunoglobulin subtype 2 [IPR003598]	0.4419748738443651	0.4114122660549626	0.6807702611812867	1.0	0.7602477462187192	7	Q9Y639	1
+Immunoglobulin subtype [IPR003599]	0.4419748738443651	0.4114122660549626	0.6807702611812867	1.0	0.7602477462187192	7	Q9Y639	1
+Band 7 domain [IPR001107]	0.4550052142052142	0.4079660712333643	0.6832985843408004	1.0	0.7623417284184646	6	Q99623,Q9UJZ1	2
+Acyl-CoA oxidase/dehydrogenase, central domain [IPR006091]	0.4151169843275943	0.4063750657572537	0.6844670375313111	1.0	0.7632804900134162	9	O15254	1
+GHMP kinase, C-terminal domain [IPR013750]	0.4693140794223762	0.378648865792321	0.7049486297706093	1.0	0.7803209079362264	2	Q03426	1
+CDC48, domain 2 [IPR004201]	0.4682310469314025	0.3750171436692793	0.7076477167740385	1.0	0.7812912823796622	2	P55072	1
+CDC48, N-terminal subdomain [IPR003338]	0.4682310469314025	0.3750171436692793	0.7076477167740385	1.0	0.7812912823796622	2	P55072	1
+Serine-threonine/tyrosine-protein kinase, catalytic domain [IPR001245]	0.4521889285739091	0.3670952555433093	0.7135479661554498	1.0	0.7870609418746786	5	Q9UHY1	1
+TRASH domain [IPR011017]	0.4642599277978272	0.3618421382733822	0.7174700009558956	1.0	0.7887776647343667	2	P83731	1
+ATPase, AAA-type, core [IPR003959]	0.3216947014674663	0.3598896607535936	0.7189296492315287	1.0	0.7900102642685443	26	Q9NVI7,Q9Y276,Q8NBU5,Q96TA2	4
+SNF2, N-terminal [IPR000330]	0.3651032325444613	0.3493232443786945	0.7268466497937562	1.0	0.7977342059988164	12	Q14527,Q86WJ1,Q2NKX8,P46100,P28370	5
+LSM domain, eukaryotic/archaea-type [IPR001163]	0.4299130410749622	0.3295923191618337	0.7417080270253371	1.0	0.8104618609911689	6	P62314	1
+Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase [IPR006186]	0.4370195977813554	0.3225381620712972	0.7470450319768485	1.0	0.8151487165189174	5	Q08209	1
+Disulphide isomerase [IPR005788]	0.4141669678351927	0.2605088747854369	0.794471270496045	1.0	0.858470345063782	5	P13667,P07237,P30101,Q8NBS9	4
+TIP49, P-loop domain [IPR010339]	0.4296028880866373	0.2569972183136745	0.7971809204379441	1.0	0.8602746273331929	2	Q9Y265	1
+RuvB-like, AAA-lid domain [IPR041048]	0.4296028880866373	0.2569972183136745	0.7971809204379441	1.0	0.8602746273331929	2	Q9Y265	1
+Nucleoside phosphorylase domain [IPR000845]	0.4281588447653369	0.2530490461269676	0.8002303128919976	1.0	0.863094986270759	2	P00491	1
+2Fe-2S ferredoxin-type iron-sulfur binding domain [IPR001041]	0.4238267148014367	0.2414171643883381	0.8092318108575236	1.0	0.8715953145092109	2	P28331	1
+Nucleotidyl transferase domain [IPR005835]	0.5077645359335556	0.2280757568336885	0.8195873466723311	1.0	0.880716789656179	3	Q96IJ6,Q9Y5P6	2
+Ribosomal protein L7, eukaryotic/archaeal [IPR035808]	0.4162454873646136	0.221839297069003	0.8244389869061615	1.0	0.8843017442274729	2	P18124	1
+Ribosomal protein L30, N-terminal [IPR012988]	0.4162454873646136	0.221839297069003	0.8244389869061615	1.0	0.8843017442274729	2	P18124	1
+Ribosomal protein L30, ferredoxin-like fold domain [IPR016082]	0.4162454873646136	0.221839297069003	0.8244389869061615	1.0	0.8843017442274729	2	P18124	1
+Immunoglobulin-like domain [IPR007110]	0.3331158404412411	0.202842290869171	0.8392583016535995	1.0	0.8989577219180822	11	Q9Y639	1
+Zinc finger, FYVE-related [IPR017455]	0.4712451337892456	0.1859369686777431	0.8524941908719534	1.0	0.9101450168789976	4	Q9P2R3,Q96T51	2
+FYVE zinc finger [IPR000306]	0.4712451337892456	0.1859369686777431	0.8524941908719534	1.0	0.9101450168789976	4	Q9P2R3,Q96T51	2
+Septin-type guanine nucleotide-binding (G) domain [IPR030379]	0.3787793426569537	0.1779813235389526	0.858737643212528	1.0	0.9156206757688626	5	Q9UHD8,Q14141	2
+PIK-related kinase, FAT [IPR003151]	0.3935018050541447	0.169206119582552	0.8656345164674062	1.0	0.9204514630683036	2	P42345	1
+PIK-related kinase [IPR014009]	0.3935018050541447	0.169206119582552	0.8656345164674062	1.0	0.9204514630683036	2	P42345	1
+FATC domain [IPR003152]	0.3935018050541447	0.169206119582552	0.8656345164674062	1.0	0.9204514630683036	2	P42345	1
+Domain of unknown function DUF1605 [IPR011709]	0.3283249919803479	0.1654026018427692	0.8686271059084398	1.0	0.9223729140993168	10	Q9H2U1,Q9H6S0,Q7L2E3,Q7Z478	4
+Helicase-associated domain [IPR007502]	0.3283249919803479	0.1654026018427692	0.8686271059084398	1.0	0.9223729140993168	10	Q9H2U1,Q9H6S0,Q7L2E3,Q7Z478	4
+Phox homology [IPR001683]	0.3417984009240637	0.1597214038641189	0.8731005395127913	1.0	0.9267005582795548	8	Q13596	1
+GHMP kinase N-terminal domain [IPR006204]	0.4694835680751152	0.1567333830756483	0.8754549763294543	1.0	0.9283561629954324	3	Q03426,P53602	2
+SMARCC, SWIRM-associated domain [IPR032448]	0.3844765342960232	0.1509014258282845	0.8800534757196665	1.0	0.9315395974284362	2	Q8TAQ2	1
+SMARCC, C-terminal [IPR032451]	0.3844765342960232	0.1509014258282845	0.8800534757196665	1.0	0.9315395974284362	2	Q8TAQ2	1
+SMARCC, N-terminal [IPR032450]	0.3844765342960232	0.1509014258282845	0.8800534757196665	1.0	0.9315395974284362	2	Q8TAQ2	1
+EF-hand domain [IPR002048]	0.2598633232266062	0.1475408906910869	0.8827051067626028	1.0	0.9327312062372994	38	O95202,Q9H4M9,P80303,O95302,P35609	5
+Tubulin/FtsZ, GTPase domain [IPR003008]	0.3559066808906926	0.145837185258275	0.884049920122407	1.0	0.9327312062372994	6	P68371,P04350,Q13885	3
+Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]	0.3559066808906926	0.145837185258275	0.884049920122407	1.0	0.9327312062372994	6	P68371,P04350,Q13885	3
+Serine-tRNA ligase catalytic core domain [IPR033729]	0.3815884476534232	0.1453551383833572	0.8844304827957647	1.0	0.9327312062372994	2	P49591	1
+WHEP-TRS domain [IPR000738]	0.4476156069364276	0.1449176709747124	0.8847758742970784	1.0	0.9327312062372994	4	P41250,P23381,P56192	3
+Formin, FH2 domain [IPR015425]	0.4420504115439202	0.1362107167654714	0.8916547033759532	1.0	0.9372896857311614	4	Q9NSV4	1
+Rho GTPase-binding/formin homology 3 (GBD/FH3) domain [IPR014768]	0.4420504115439202	0.1362107167654714	0.8916547033759532	1.0	0.9372896857311614	4	Q9NSV4	1
+RecF/RecN/SMC, N-terminal [IPR003395]	0.3464888800622324	0.1282645905654665	0.8979395862334303	1.0	0.9423520657683572	6	O95347,Q9NTJ3,Q8IY18	3
+Reticulon [IPR003388]	0.4361362725230915	0.1273565404024553	0.8986582118097493	1.0	0.9423575862743682	4	O95197	1
+Bromo adjacent homology (BAH) domain [IPR001025]	0.4360549132948095	0.1272375946881081	0.8987523509197701	1.0	0.9423575862743682	4	O94776,Q13330,P26358	3
+Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) [IPR002314]	0.3452639190166223	0.1260804545525003	0.8996682390034854	1.0	0.9428943286188302	6	Q9BW92,P49591,Q9NP81,P41250,P07814	5
+SANT domain [IPR017884]	0.3333047799772846	0.1218578210191884	0.9030116205560328	1.0	0.9433038344070211	7	P28370,Q8TAQ2,O60264	3
+RBM3/CIRBP, RNA recognition motif [IPR034278]	0.368231046931402	0.1216539988618411	0.9031730461359128	1.0	0.9433038344070211	2	Q14011	1
+Sterile alpha motif domain [IPR001660]	0.4289210316079428	0.1171085409601204	0.9067740416032668	1.0	0.9460932557452056	4	Q9Y3Z3,Q9UQR0	2
+Ubiquitin-conjugating enzyme E2 [IPR000608]	0.3197100929051	0.114634834458469	0.9087345678013352	1.0	0.9477151390743148	8	Q16763	1
+HD/PDEase domain [IPR003607]	0.3602888086642539	0.1090625809067171	0.9131528539096376	1.0	0.949455900409392	2	Q9Y3Z3	1
+HD domain [IPR006674]	0.3602888086642539	0.1090625809067171	0.9131528539096376	1.0	0.949455900409392	2	Q9Y3Z3	1
+Sec63 domain [IPR004179]	0.4364106066454005	0.1087369548299611	0.913411129910138	1.0	0.949455900409392	3	Q9UGP8	1
+SWIRM domain [IPR007526]	0.4217826749323751	0.1075646304031796	0.9143410550054978	1.0	0.9497427780964984	4	Q8TAQ2,O60341	2
+BAT2, N-terminal [IPR009738]	0.3588447653429541	0.1068914561663696	0.9148750913480724	1.0	0.9498747612128116	2	P48634	1
+Ribosomal L28e/Mak16 [IPR029004]	0.3584837545126292	0.1063543055681439	0.9153012462564768	1.0	0.9498946681914704	2	P46779	1
+Major sperm protein (MSP) domain [IPR000535]	0.431202600216686	0.1023193048001355	0.9185032327100662	1.0	0.9520524497137332	3	Q8NHP6,O95292	2
+B3/B4 tRNA-binding domain [IPR005146]	0.3530685920577556	0.0985651700117353	0.9214835256191208	1.0	0.95376609702662	2	Q8N1G4	1
+Threonine-tRNA ligase catalytic core domain [IPR033728]	0.3447653429602824	0.0875812337741125	0.9302095181342068	1.0	0.9610929682714648	2	Q9BW92	1
+Lactate/malate dehydrogenase, C-terminal [IPR022383]	0.4039017341040576	0.08620682132637	0.9313020082627534	1.0	0.961370582611794	4	P07195,P40925,P40926	3
+Lactate/malate dehydrogenase, N-terminal [IPR001236]	0.4039017341040576	0.08620682132637	0.9313020082627534	1.0	0.961370582611794	4	P07195,P40925,P40926	3
+SANT/Myb domain [IPR001005]	0.2932747332117765	0.0795944986439878	0.9365597707820206	1.0	0.96326173422632	9	P28370,Q8TAQ2,O60264,Q8IXM2	4
+Histidine kinase/HSP90-like ATPase [IPR003594]	0.3048236177166306	0.0767071304440803	0.9388565319827976	1.0	0.9636284721406552	7	Q12931,Q15120,P08238	3
+Domain of unknown function DUF4749 [IPR031847]	0.3328519855595603	0.073773766568374	0.941190401374373	1.0	0.965599295300126	2	O00151	1
+SAP domain [IPR003034]	0.25471251031152	0.0560426844044192	0.9553078033360662	1.0	0.976413883334539	13	Q00839,P35659,P82979,Q9NWH9	4
+NOPS [IPR012975]	0.362224629830263	0.0437363230081479	0.965114585333557	1.0	0.981087736136116	3	P23246,Q15233	2
+Anticodon-binding [IPR004154]	0.3450144508670562	0.0392844916072827	0.9686635709766168	1.0	0.9827437552114252	4	Q9BW92,P07814,P41250	3
+Cation-transporting P-type ATPase, N-terminal [IPR004014]	0.3446531791907554	0.0390935838891376	0.9688157763752908	1.0	0.9827437552114252	4	P98194,P05023,P20020	3
+Cation-transporting P-type ATPase, C-terminal [IPR006068]	0.3446531791907554	0.0390935838891376	0.9688157763752908	1.0	0.9827437552114252	4	P98194,P05023,P20020	3
+Brix domain [IPR007109]	0.3528349584687604	0.039052012009489	0.9688489206261736	1.0	0.9827437552114252	3	Q9H7B2,Q8TDN6	2
+Serine-threonine protein phosphatase, N-terminal [IPR031675]	0.2642599277978265	0.0305562729629888	0.9756234149714548	1.0	0.9874696663241004	2	P62136	1
+Cullin homology domain [IPR016158]	0.2580411998554394	0.028944899682249	0.9769085358404488	1.0	0.987913571339518	5	Q13616,Q93034,Q13617,Q13618	4
+Cullin protein, neddylation domain [IPR019559]	0.2580411998554394	0.028944899682249	0.9769085358404488	1.0	0.987913571339518	5	Q13616,Q93034,Q13617,Q13618	4
+Cullin, N-terminal [IPR001373]	0.2581344902386031	0.0271651566212745	0.9783280064320709	1.0	0.9889205573895424	6	Q13618,Q13616,Q93034,Q86Y37,Q13617	5
+Glutamine amidotransferase type 2 domain [IPR017932]	0.2723004694835619	0.0193299342053909	0.9845779043438052	1.0	0.9935170033456296	3	Q06203,Q06210	2
+Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant [IPR000866]	0.2337427745664787	0.0140379478237313	0.9887997060297128	1.0	0.9962745728205552	4	P30041,P30048,P32119	3
+Peroxiredoxin, C-terminal [IPR019479]	0.2337427745664787	0.0140379478237313	0.9887997060297128	1.0	0.9962745728205552	4	P30041,P30048,P32119	3