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Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
Mitochondrial fatty acid beta oxidation of saturated fatty acids 0.9157348417900576 2.520024100208067 0.0117346799492668 0.999999892065098 1.0 6 P11310 1
Pkmts methylate histone lysines 0.8152812886135515 2.2135683117720246 0.0268584891859973 1.0 1.0 10 Q9H7B4 1
Striated muscle contraction 0.8344179320318204 1.991968466573618 0.0463745178414769 1.0 1.0 5 P35609,P67936,P08670,Q9NYL9 4
Heme degradation 0.8306392478757011 1.9768058207806511 0.0480635834990836 1.0 1.0 5 P30519 1
Metabolism of porphyrins 0.7616397589786231 1.9477399601213352 0.0514460860841765 1.0 1.0 9 P30519,P33527 2
Transcriptional activation of mitochondrial biogenesis 0.7484602181951974 1.9153350872614592 0.0554497836497058 1.0 1.0 10 Q04837,P48735,P06576,P04179,Q96RR1 5
Polo like kinase mediated events 0.929770091873517 1.9093612144167476 0.056215510556081 1.0 1.0 3 P14635 1
Alpha linolenic omega3 and linoleic omega6 acid metabolism 0.7660404942657877 1.8987195752066792 0.0576013563790045 1.0 1.0 6 Q15067 1
Respiratory electron transport 0.4969617875607212 1.8616849902531547 0.062647505509886 1.0 1.0 48 P21912,P22695,Q16718,O95168,Q16795,Q9BSH4,O75306,O95182,P14927,Q7L592,Q9NX14,P09669,O43676,P15954,O14949,Q12931,O75489,O00483,P47985,P20674 20
Signaling by hippo 0.7564866998408635 1.8576788726629376 0.0632146304982905 1.0 1.0 6 Q07157 1
Binding and uptake of ligands by scavenger receptors 0.7542525746251338 1.8480595246926952 0.0645937322439538 1.0 1.0 6 P27797,Q9Y4L1,Q8WTV0 3
Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins 0.5211520364722086 1.844916285227281 0.0650497173157362 1.0 1.0 58 P21912,P22695,Q16718,O75947,P00846,O95168,P56385,Q16795,P36542,Q9BSH4,O75306,O95182,P14927,Q7L592,P24539,Q9NX14,P09669,O43676,P15954,O14949,Q12931,O75489,O00483,P47985,P06576,P20674 26
G2 m dna replication checkpoint 0.9102348112512898 1.8356180615592668 0.0664141640019906 1.0 1.0 3 P14635 1
Rhog gtpase cycle 0.5002822669885006 1.8060353713215984 0.0709128146951902 1.0 1.0 33 P61604,Q86XL3,Q6IAA8,P42167,Q13017,O75489,O15173,Q96JJ3,O95292,O95202,Q13190,Q16718,P51149,P42166,Q86UP2 15
Platelet aggregation plug formation 0.7349332736354413 1.7645387441512794 0.077641318286544 1.0 1.0 6 P31749 1
Integrin signaling 0.7349332736354413 1.7645387441512794 0.077641318286544 1.0 1.0 6 P31749 1
Mitochondrial fatty acid beta oxidation 0.6708186433237827 1.7408383097018736 0.0817119246848256 1.0 1.0 16 P11310 1
Mastl facilitates mitotic progression 0.7699983111754471 1.7305318210459546 0.083535300990388 1.0 1.0 5 P30154,P14635 2
Signaling by retinoic acid 0.7027958216265043 1.7067025420431197 0.0878773544974538 1.0 1.0 10 O94788 1
Chk1 chk2 cds1 mediated inactivation of cyclin b cdk1 complex 0.7015840634737022 1.7011186569405248 0.0889207082048875 1.0 1.0 10 P14635 1
Signaling by alk 0.7616034337205249 1.696032131432057 0.0898797951757608 1.0 1.0 5 Q96ST3,P19174 2
Mitochondrial biogenesis 0.5070810309074909 1.662668585762553 0.0963787937890723 1.0 1.0 31 P00846,Q16891,P48735,Q04837,Q6UXV4,P56385,Q13505,Q00059,P06576,P36542,P04179,Q96RR1,O75947 13
Calnexin calreticulin cycle 0.7029227835526652 1.6618934804997094 0.0965341341238461 1.0 1.0 8 P27797,Q9NYU2,P14314,P27824,Q9GZP9 5
Foxo mediated transcription of oxidative stress metabolic and neuronal genes 0.8227209709988652 1.6464320642182255 0.0996748361523329 1.0 1.0 4 Q96ST3 1
Gaba receptor activation 0.7003021004502246 1.613410999732947 0.1066552449528754 1.0 1.0 6 P04899,Q9Y639 2
Phosphorylation of the apc c 0.6859994154782785 1.606313815797412 0.1082049762797978 1.0 1.0 9 Q9UJX4 1
Mitochondrial protein import 0.4475667070992433 1.604064262016679 0.1086998883992449 1.0 1.0 35 Q5JRX3,Q9Y584,Q99595,Q10713,O75439,O14925,O60830,O75746,Q9Y276,Q13505,O96008,P06576,P51553,P12235,Q8N4H5 15
Apc c cdc20 mediated degradation of cyclin b 0.689080581772094 1.599585638928782 0.1096905364262772 1.0 1.0 8 Q9UJX4 1
Suppression of phagosomal maturation 0.6948584665042632 1.5895069525524517 0.1119459856512685 1.0 1.0 6 P52294,P20339,P51149,O14964 4
Long term potentiation 0.8035749274397315 1.5736785641966478 0.1155617799452999 1.0 1.0 4 P07196,P35609 2
Unblocking of nmda receptors glutamate binding and activation 0.8035749274397315 1.5736785641966478 0.1155617799452999 1.0 1.0 4 P07196,P35609 2
Ras activation upon ca2 influx through nmda receptor 0.8035749274397315 1.5736785641966478 0.1155617799452999 1.0 1.0 4 P07196,P35609 2
Beta catenin phosphorylation cascade 0.7259202623860099 1.5484468767747317 0.1215147424480207 1.0 1.0 5 P30154 1
Signaling by ctnnb1 phospho site mutants 0.7259202623860099 1.5484468767747317 0.1215147424480207 1.0 1.0 5 P30154 1
Disassembly of the destruction complex and recruitment of axin to the membrane 0.7259202623860099 1.5484468767747317 0.1215147424480207 1.0 1.0 5 P30154 1
Smooth muscle contraction 0.6549765565430617 1.507882908463363 0.1315844977371238 1.0 1.0 11 P07355,P08133,P06753,P04083,P67936 5
Transcriptional regulation by e2f6 0.6743023974135387 1.49892916932319 0.1338920082057479 1.0 1.0 6 P45973,Q13185,Q96KQ7 3
Pp2a mediated dephosphorylation of key metabolic factors 0.8166116121080049 1.477191201740199 0.139624391560091 1.0 1.0 3 P30154 1
Signaling by ptk6 0.6299904848069967 1.4675233294657215 0.1422337476661783 1.0 1.0 14 P31749,Q96JJ3,P46108,P23246 4
Muscle contraction 0.5689800587739233 1.453462545420076 0.1460953716640092 1.0 1.0 22 P07355,P08670,Q12797,P08133,P06753,P04083,P35609,P67936,Q9NYL9 9
Nr1h2 and nr1h3 mediated signaling 0.699479556853783 1.438268749883925 0.1503578150358038 1.0 1.0 5 O00767 1
Rhof gtpase cycle 0.6160243282915228 1.4279980107188608 0.1532924310979573 1.0 1.0 15 Q13017,P42166,P80723,Q5JTV8 4
Dap12 interactions 0.6903278660634358 1.4000116175250394 0.1615098395706713 1.0 1.0 5 P01889 1
Dna replication initiation 0.6519463391883527 1.3999529747905524 0.1615274008619542 1.0 1.0 6 Q9NR33 1
Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps 0.6124576638185982 1.3801863935799048 0.167529262266159 1.0 1.0 14 Q13217,Q07065,Q15293,P14314,O43852,Q86UP2,Q15084 7
Generation of second messenger molecules 0.7911844407828549 1.378878713386286 0.1679321523099286 1.0 1.0 3 P19174 1
Regulation of lipid metabolism by pparalpha 0.5970720021545083 1.3630109336103002 0.1728790648044322 1.0 1.0 16 P11310,Q96ST3,Q15067 3
Mecp2 regulates neuronal receptors and channels 0.6397428210369593 1.3598170631347593 0.1738878213901347 1.0 1.0 7 Q9NWH9,Q92769,Q96ST3,P51608 4
Stat3 nuclear events downstream of alk signaling 0.745990321241381 1.353274573803609 0.1759679289249354 1.0 1.0 4 Q96ST3 1
Er quality control compartment erqc 0.7829858481609056 1.3471451468247608 0.1779334902571148 1.0 1.0 3 Q9GZP9 1
Negative regulation of nmda receptor mediated neuronal transmission 0.6773581409619942 1.3457161710370602 0.1783940691638381 1.0 1.0 5 P07196,P35609 2
Runx1 regulates genes involved in megakaryocyte differentiation and platelet function 0.6245405163750694 1.3422934812850988 0.1795008562196551 1.0 1.0 10 Q96ST3,Q03164 2
Rna polymerase ii transcription termination 0.410284106380899 1.3328298349220409 0.1825876525189667 1.0 1.0 39 P82979,O43809,Q13242,Q13247,Q16629,Q07955,Q8N684,Q96FV9,Q9Y5S9,O00148,Q92989 11
Signaling by nuclear receptors 0.4461527629957447 1.332527919466551 0.1826867733067354 1.0 1.0 53 O00767,P63218,O94788,P31749,Q01469,Q13951,P04899,Q8NB78 8
G alpha 12 13 signalling events 0.6273356688429974 1.3191484621014509 0.1871194842323542 1.0 1.0 8 O75116,P63218 2
Rhobtb1 gtpase cycle 0.5746200432283123 1.313729407680358 0.1889372809059391 1.0 1.0 18 P08670,P61201,O75116,P62995,Q8N684,P07910,P38159,Q9BT78,Q7Z6E9 9
Runx2 regulates genes involved in cell migration 0.7734826589595192 1.3103558571989924 0.1900754794634762 1.0 1.0 3 P31749,Q13951 2
Ire1alpha activates chaperones 0.5316907174097153 1.2842084675245942 0.1990690232323904 1.0 1.0 23 Q969H8,P43307,Q13217,O14773,P49748,Q9Y4L1,Q9NWM8,P08240,Q15084 9
Activation of bad and translocation to mitochondria 0.6158725019935998 1.2832205141811297 0.199414830883944 1.0 1.0 9 P31749 1
Response to elevated platelet cytosolic ca2 0.464063379511314 1.272083507280856 0.2033434504286519 1.0 1.0 30 P55145,Q9NUQ9,O94919,Q9Y6I9,O15439,Q9BWS9,P35609,O43852 8
Listeria monocytogenes entry into host cells 0.6180280570341696 1.2620342768068993 0.2069364526944779 1.0 1.0 7 Q92783 1
Prevention of phagosomal lysosomal fusion 0.7593930635837952 1.25582351515112 0.209179963904678 1.0 1.0 3 P20339,O14964 2
Protein folding 0.3957097056032515 1.252565623907454 0.2103638318764886 1.0 1.0 37 P63218,O95302,P61962,Q9BUR4,P61758,P19784,Q13885,O15212,Q99426,Q9Y2T2 10
Formation of atp by chemiosmotic coupling 0.6045747685488618 1.2485670497070942 0.2118234703575099 1.0 1.0 10 P00846,P56385,P06576,P36542 4
Chromatin modifying enzymes 0.432962188010372 1.2435117991382816 0.2136792957116111 1.0 1.0 52 Q9H7B4,Q03164,Q8NB78 3
E2f mediated regulation of dna replication 0.6034899842046945 1.2434734558116145 0.2136934165582635 1.0 1.0 10 P30154,P14635,Q14181,Q9Y619 4
E2f enabled inhibition of pre replication complex formation 0.7159135266360291 1.2376693695502177 0.2158386811257853 1.0 1.0 4 P14635 1
Ptk6 regulates rho gtpases ras gtpase and map kinases 0.6152023099642957 1.2366607965287757 0.216213038807745 1.0 1.0 6 P46108,Q96JJ3,P20936 3
Transcriptional regulation of granulopoiesis 0.607508172382135 1.2286314551317024 0.2192100164062571 1.0 1.0 8 Q13951,Q03164,P35659 3
Signaling by fgfr1 in disease 0.6039358327324349 1.2123231921089304 0.2253886894892689 1.0 1.0 8 O95684,O95429 2
Early phase of hiv life cycle 0.6022594169791373 1.204671063294933 0.2283303111142811 1.0 1.0 8 P17096 1
Notch3 activation and transmission of signal to the nucleus 0.7437668917558469 1.195406997267705 0.2319280531345695 1.0 1.0 3 Q92542 1
Nuclear signaling by erbb4 0.7434971098265807 1.1943648554481718 0.2323352781085947 1.0 1.0 3 P16949,Q92542 2
Endosomal sorting complex required for transport escrt 0.6024145549333291 1.191698650667686 0.2333794273403411 1.0 1.0 7 Q92783 1
G protein beta gamma signalling 0.6029047412132429 1.1819779041607403 0.237214468334729 1.0 1.0 6 P63218 1
Egfr downregulation 0.6022647519155548 1.179133253676941 0.2383451189693559 1.0 1.0 6 Q92783 1
Depolymerisation of the nuclear lamina 0.5959933499064667 1.1760771534638188 0.2395640465661297 1.0 1.0 8 P42167,P02545,P20700,P14635,P42166 5
Inlb mediated entry of listeria monocytogenes into host cell 0.636101011979843 1.1727758330734963 0.2408857118659977 1.0 1.0 5 Q92783 1
Cell cell junction organization 0.598108114974321 1.1606619428208236 0.2457794043281636 1.0 1.0 6 P14923,Q9Y624 2
Fgfr1 mutant receptor activation 0.5944232859000378 1.155725577422697 0.2477934226913862 1.0 1.0 7 O95684 1
Negative regulation of met activity 0.5928763465630191 1.1374257806073778 0.2553603350103688 1.0 1.0 6 Q92783 1
G beta gamma signalling through pi3kgamma 0.6226672779262019 1.1165514766926952 0.2641861486101726 1.0 1.0 5 P63218 1
Inhibition of replication initiation of damaged dna by rb1 e2f1 0.5861607680000895 1.1076266990817163 0.2680230678878468 1.0 1.0 6 P30154,Q14181 2
Rhobtb gtpase cycle 0.4662440608782366 1.0902425876412 0.2756062979639684 1.0 1.0 27 P08670,O75116,P62995,Q8N684,P07910,P38159 6
Rhoj gtpase cycle 0.5311812137830366 1.0811612456935271 0.2796253935910568 1.0 1.0 18 P42167,Q6IAA8,Q15758,Q13017,Q14155,P14923,Q14160,P42166 8
N glycan trimming in the er and calnexin calreticulin cycle 0.5467815274160819 1.07670827264355 0.281610615398896 1.0 1.0 15 Q14165,P27797,Q9NYU2,P14314,P27824,Q9GZP9 6
Formation of senescence associated heterochromatin foci sahf 0.5724571829298907 1.057078604393659 0.2904757149609696 1.0 1.0 7 P07305,P20700,P04637,P17096 4
Transcriptional regulation by the ap 2 tfap2 family of transcription factors 0.6678516899747272 1.0534197976867226 0.2921486345057162 1.0 1.0 4 P06748 1
Tp53 regulates metabolic genes 0.3802831905099669 1.0450359263225188 0.2960063654564799 1.0 1.0 35 Q6IAA8,P13073,P31749,Q04917,O00483,Q9Y2Q5,P54619,P09669,P15954,P31751,P20674,Q9BSH4 12
Cilium assembly 0.4086970618720695 1.0420663828452392 0.2973809030838801 1.0 1.0 52 Q9H6D7,O43924,O95684,O75695,Q96KP1,Q92973,P30153,Q13885,O94927,Q9NQ48,Q96A65,Q92538 12
Unfolded protein response upr 0.3759495119751273 1.038942795878521 0.2988313413902235 1.0 1.0 39 Q969H8,Q06265,P43307,P02545,P27797,Q13217,O14773,Q96B26,P49748,Q9Y4L1,Q9NWM8,P08240,Q15084 13
Insulin processing 0.5643970176619055 1.032327258845896 0.3019188355272875 1.0 1.0 8 Q96KP1,Q96A65 2
Met activates ras signaling 0.6573906758221816 1.0135646723177445 0.3107905220184923 1.0 1.0 4 Q9NWH9,Q96P70,Q96S59 3
Vxpx cargo targeting to cilium 0.5601881937004384 1.0132693399351762 0.3109315281077875 1.0 1.0 8 Q96KP1,Q96A65 2
Translocation of slc2a4 glut4 to the plasma membrane 0.3861829272819402 1.004649273592836 0.3150657620220605 1.0 1.0 34 Q9UIQ6,Q96KP1,P31749,Q04917,P54619,Q13885,Q96A65 7
Metabolism of cofactors 0.5943295444112316 0.9984851910486088 0.3180441419388478 1.0 1.0 5 O75874,P31749 2
Signaling by flt3 fusion proteins 0.6924354378857475 0.9982561375906892 0.3181551710103747 1.0 1.0 3 Q14789 1
Recruitment of numa to mitotic centrosomes 0.4248729797723461 0.9949784376494216 0.31974675155281 1.0 1.0 30 Q9H6D7,O95684,P68371,Q15154,P43034,P30153,Q13885,P07437,O94927,Q96CW5 10
Collagen biosynthesis and modifying enzymes 0.5500740944867186 0.9935714983218304 0.3204315258047892 1.0 1.0 10 P50454,O75718,Q32P28,P07237 4
Slc mediated transmembrane transport 0.5199986512631478 0.992457046045445 0.3209746230026571 1.0 1.0 17 Q99808,Q70HW3,Q8TAD4,Q9UBX3 4
Receptor mediated mitophagy 0.687937799771296 0.9811425763563926 0.326522437044197 1.0 1.0 3 Q96HS1 1
Maturation of sars cov 1 spike protein 0.6488063648617289 0.9809672863670608 0.3266088740543642 1.0 1.0 4 P14314,P27824 2
Regulation of beta cell development 0.6860549132947761 0.9739887224713072 0.3300621387853799 1.0 1.0 3 P31749,P31751 2
Aurka activation by tpx2 0.4635121974717669 0.968543232898188 0.3327731384381298 1.0 1.0 25 Q9H6D7,O95684,Q9ULW0,P68371,Q15154,P30153,P07437,O94927 8
Endosomal vacuolar pathway 0.6455266028145613 0.9685423715495504 0.33277356838877 1.0 1.0 4 P01889,Q9UIQ6 2
Rhoa gtpase cycle 0.3721552449854126 0.9641758741641075 0.3349577578237168 1.0 1.0 41 Q86UP2,P30519,Q13017,O75116,Q96HY6,Q92974,P42166 7
Immunoregulatory interactions between a lymphoid and a non lymphoid cell 0.5533944950400891 0.962986609604174 0.3355542431350491 1.0 1.0 6 P78310 1
Transport of inorganic cations anions and amino acids oligopeptides 0.5510884269170027 0.9617123083823612 0.3361941378454189 1.0 1.0 7 Q70HW3,P08195,Q9UBX3 3
Complex i biogenesis 0.4696068762901479 0.9597613922100742 0.3371753172876959 1.0 1.0 24 O75306,O95182,Q7L592,Q16795,O43676,Q16718 6
Recruitment of mitotic centrosome proteins and complexes 0.4536065132281138 0.9557359100343372 0.3392056751229668 1.0 1.0 26 Q9H6D7,O95684,P68371,Q15154,P30153,P07437,O94927,Q96CW5 8
Condensation of prophase chromosomes 0.5397569968533191 0.9457693385938836 0.3442662475796019 1.0 1.0 10 P14635,Q01105 2
Interleukin 4 and interleukin 13 signaling 0.5327774380219329 0.9443771224353068 0.3449769679404173 1.0 1.0 12 P04083,P31749 2
Signaling by erbb4 0.5470711267149527 0.9438804013638628 0.3452307682387665 1.0 1.0 7 P16949,Q92542,P46934 3
Cargo trafficking to the periciliary membrane 0.4936286871791042 0.9432072790870912 0.3455748908969553 1.0 1.0 20 O43924,Q96A65,Q96KP1 3
Foxo mediated transcription 0.5313685955597633 0.937673077254741 0.348412443688376 1.0 1.0 12 P04179,Q96ST3 2
Regulation of tp53 activity through association with co factors 0.6752167630057574 0.9329423019705574 0.3508497595824829 1.0 1.0 3 P31749,P31751 2
Activation of bh3 only proteins 0.5336521068058381 0.9321147075869136 0.3512772479583499 1.0 1.0 11 P31749 1
Antigen presentation folding assembly and peptide loading of class i mhc 0.5230442255807626 0.9157231802732686 0.3598121038804573 1.0 1.0 13 P01889,P27797,Q9NZ08,P27824,P30101 5
Notch hlh transcription pathway 0.6702987631153385 0.9143976622744704 0.3605079297577054 1.0 1.0 3 Q92769 1
Cell death signalling via nrage nrif and nade 0.5307113272817867 0.9040746867365922 0.3659557997937344 1.0 1.0 10 Q92974 1
Cristae formation 0.4832373154943121 0.8864371618143854 0.3753820014264226 1.0 1.0 20 P00846,Q16891,Q6UXV4,P56385,Q13505,P06576,P36542,O75947 8
Runx1 regulates transcription of genes involved in differentiation of myeloid cells 0.8757674250632015 0.8808456210769667 0.3784013834441206 1.0 1.0 2 Q13951 1
Nephrin family interactions 0.5282647412902918 0.8805361994953464 0.3785689038375335 1.0 1.0 9 Q01082,P16333,O43707,Q13813,Q9Y5K6,P35609 6
Synthesis of ketone bodies 0.6591648771449101 0.8726254127511135 0.3828672843528464 1.0 1.0 3 P35610 1
Ketone body metabolism 0.6591648771449101 0.8726254127511135 0.3828672843528464 1.0 1.0 3 P35610 1
Citric acid cycle tca cycle 0.4843936070989763 0.8621088426453302 0.3886276258316892 1.0 1.0 19 Q13423 1
Class b 2 secretin family receptors 0.6558740341675418 0.8603397718668844 0.3896017752158942 1.0 1.0 3 P63218 1
Lysosome vesicle biogenesis 0.5098256250700274 0.8523226934354059 0.3940350139726682 1.0 1.0 13 Q8NBS9,P51809,O14964,Q10567 4
Signaling by vegf 0.4286607823502072 0.8481016812097231 0.3963813454221589 1.0 1.0 27 P04792,O75116,P31749,Q9UQB8,P46108,P19174,Q96JJ3 7
Scavenging by class f receptors 0.6130695212367976 0.8467057962748353 0.3971591271515318 1.0 1.0 4 P27797 1
Dissolution of fibrin clot 0.6505765261542168 0.8406261504928692 0.4005574040237709 1.0 1.0 3 P60903 1
Organelle biogenesis and maintenance 0.4544239839050016 0.8377571830515871 0.4021670904723797 1.0 1.0 83 P54619,O94927,O75947,P00846,O43924,Q9H6D7,P48735,Q6UXV4,P56385,Q96KP1,Q13505,Q00059,P36542,Q96A65,Q9NQ48,Q92538,O95684,P24539,P30153,Q13885,Q16891,Q04837,O75695,P06576,Q92973,P04179,Q96RR1 27
Cyclin a b1 b2 associated events during g2 m transition 0.5147377107537123 0.8310660684411161 0.4059363070247468 1.0 1.0 10 P30154,P14635,Q99640 3
Runx1 regulates expression of components of tight junctions 0.8605994944023104 0.8290056929638733 0.4071011858249085 1.0 1.0 2 Q13951 1
Hur elavl1 binds and stabilizes mrna 0.551656733146868 0.8234248267514694 0.410266449643798 1.0 1.0 5 Q15717,Q01105,P35658 3
Maturation of sars cov 2 spike protein 0.5148169044050801 0.8201129658116009 0.4121517114272164 1.0 1.0 9 Q14697,P04843,P39656,P14314,P27824,P04844,P46977 7
Regulation of plk1 activity at g2 m transition 0.4000406327933745 0.7660817365227457 0.4436276692839902 1.0 1.0 29 O94927,O95684 2
Adp signalling through p2y purinoceptor 12 0.5311486816451683 0.7412430157849141 0.4585461059647531 1.0 1.0 5 P04899 1
G alpha z signalling events 0.5311486816451683 0.7412430157849141 0.4585461059647531 1.0 1.0 5 P04899 1
Gaba b receptor activation 0.5311486816451683 0.7412430157849141 0.4585461059647531 1.0 1.0 5 P04899 1
Nrage signals death through jnk 0.4980625763554102 0.7247570801324131 0.4686010705888734 1.0 1.0 6 Q14155,Q92974 2
Rna polymerase iii transcription termination 0.5269765549813332 0.724733821866608 0.468615341756476 1.0 1.0 5 P62875,O15160,P05455 3
Post translational modification synthesis of gpi anchored proteins 0.5268790755904377 0.724349033239453 0.4688514812412119 1.0 1.0 5 O60762 1
Rhobtb3 atpase cycle 0.6181358381502684 0.7219174960285955 0.4703452037390296 1.0 1.0 3 Q13618,O14964 2
Activated pkn1 stimulates transcription of ar androgen receptor regulated genes klk2 and klk3 0.6156069364161916 0.7128321293259218 0.4759496414461934 1.0 1.0 3 O60341,P62805 2
Vegfr2 mediated cell proliferation 0.6151451341227385 0.7111760208994297 0.476975165976186 1.0 1.0 3 P19174 1
Amino acid transport across the plasma membrane 0.8248465149873627 0.7098750658436915 0.4777816138561628 1.0 1.0 2 P08195 1
Neurotransmitter receptors and postsynaptic signal transmission 0.3388822107760411 0.709170589215971 0.4782186222797198 1.0 1.0 35 P04899,P63218,Q9Y639,P35609 4
Diseases of mitotic cell cycle 0.4838016028433367 0.7033347236260682 0.4818471759391745 1.0 1.0 11 Q9UJX4 1
Sensing of dna double strand breaks 0.5736138310581411 0.7025326862849822 0.482347024864669 1.0 1.0 4 Q92878,O60934 2
Mitophagy 0.4845903659387733 0.6962130958496745 0.4862953875319586 1.0 1.0 10 P19784,O96008,Q96HS1,Q8N4H5 4
Gap filling dna repair synthesis and ligation in gg ner 0.4597042695106755 0.685920500498764 0.4927632418650591 1.0 1.0 17 Q07864,Q9NR33,P18858,P18887,P35251 5
G alpha s signalling events 0.4878996316876528 0.6823855023769576 0.4949952205031747 1.0 1.0 6 P04899 1
G2 m dna damage checkpoint 0.3622257628363108 0.6792085890327005 0.4970057059162609 1.0 1.0 32 Q9UQ84,P14635 2
Ctla4 inhibitory signaling 0.4866521523641061 0.6772239578101444 0.4982638692888315 1.0 1.0 6 P30154,P31749,P30153 3
Transcription coupled nucleotide excision repair tc ner 0.3323153979200873 0.6759757267405532 0.4990560564056969 1.0 1.0 39 Q9NR33,P05114,P18858 3
Regulation of tp53 activity 0.343951192313494 0.6728128392814321 0.5010663684559282 1.0 1.0 44 Q9ULW0,P30154,Q9UQ84,P31749,Q92804,P35244,P54619,P19784,P30153,Q92769,Q96KQ7 11
Formation of the cornified envelope 0.5619922910299551 0.6612092739165338 0.5084781146726276 1.0 1.0 4 P14923,P07384 2
Keratinization 0.5619922910299551 0.6612092739165338 0.5084781146726276 1.0 1.0 4 P14923,P07384 2
Noncanonical activation of notch3 0.8096785843264667 0.6608886041368364 0.5086837547955609 1.0 1.0 2 Q92542 1
Deposition of new cenpa containing nucleosomes at the centromere 0.4809630927268062 0.6538023938879006 0.5132391240067193 1.0 1.0 6 P06748,O60264,P62805 3
Dna damage telomere stress induced senescence 0.4630838401501223 0.6487418672926877 0.5165052379672903 1.0 1.0 14 P04637,P17096,P20700,P16403,Q92878,O60934,P07305,P62805 8
Anchoring of the basal body to the plasma membrane 0.4020106120693651 0.6402334327467352 0.5220208503684742 1.0 1.0 26 O94927 1
Regulation of tp53 expression and degradation 0.4658971061593216 0.6350926460957171 0.5253679929821526 1.0 1.0 12 P30154,P31749,P30153 3
Metabolism of steroids 0.326598274757951 0.6303760604521653 0.5284485698304251 1.0 1.0 39 Q15392,O00767 2
Atf6 atf6 alpha activates chaperones 0.7999277717587547 0.62996531179729 0.5287172797893789 1.0 1.0 2 P27797 1
Scavenging by class a receptors 0.7999277717587547 0.62996531179729 0.5287172797893789 1.0 1.0 2 P27797 1
Atf6 atf6 alpha activates chaperone genes 0.7999277717587547 0.62996531179729 0.5287172797893789 1.0 1.0 2 P27797 1
Mismatch repair 0.4667011711161941 0.6278638389522946 0.5300931414790395 1.0 1.0 11 Q9UQ84 1
Glycerophospholipid catabolism 0.7973997833152788 0.6220255601531444 0.53392506104687 1.0 1.0 2 Q8IY17 1
Hdr through mmej alt nhej 0.4707916397325011 0.6215968250574929 0.5342070092278266 1.0 1.0 8 P18887 1
Mtorc1 mediated signalling 0.466356959018633 0.6171872087123542 0.537111251736013 1.0 1.0 10 P23588,Q6IAA8 2
Assembly and cell surface presentation of nmda receptors 0.4660503669536687 0.6158784039424223 0.5379747758843316 1.0 1.0 10 P07196,P35609 2
Synthesis of pg 0.7912603828096777 0.6028816917659073 0.5465873962972827 1.0 1.0 2 O95674 1
Met receptor recycling 0.5447372723545597 0.6010679048194171 0.5477947592776538 1.0 1.0 4 P46108 1
Adherens junctions interactions 0.4934186629275943 0.5952157638835445 0.5516992543424686 1.0 1.0 5 P14923 1
Darpp 32 events 0.4628428707605005 0.588784358542338 0.5560059397708064 1.0 1.0 8 P30154,P30153,P62136 3
Cholesterol biosynthesis 0.4395298481122279 0.5884433209644564 0.5562347672121581 1.0 1.0 17 Q15392 1
Apoptotic cleavage of cell adhesion proteins 0.4883865329096973 0.5763815590851066 0.564357306211642 1.0 1.0 5 Q07157 1
Role of second messengers in netrin 1 signaling 0.7811484290357481 0.5717962756017799 0.5674600007806665 1.0 1.0 2 P19174 1
Signaling by fgfr in disease 0.4435267322949228 0.5602891038991219 0.5752822583281783 1.0 1.0 14 O95684,O95429 2
Adrenaline noradrenaline inhibits insulin secretion 0.5321248640413383 0.5581550952239818 0.5767384812689278 1.0 1.0 4 P04899 1
Autophagy 0.3264420461286086 0.5551454325805276 0.5787951892202505 1.0 1.0 43 P08670,Q6IAA8,P50542,Q9Y2Q5,P54619,P19784,O96008,Q9Y4P1,Q13885,Q96HS1,Q8N4H5 11
Runx1 interacts with co factors whose precise effect on runx1 targets is not known 0.4486423735749462 0.5505606600155037 0.5819348830670654 1.0 1.0 11 Q969G3,Q13951,Q8TAQ2 3
Regulation of gene expression in beta cells 0.773203322499078 0.547781979559923 0.5838416135994753 1.0 1.0 2 P31749 1
Downregulation of erbb2 erbb3 signaling 0.773203322499078 0.547781979559923 0.5838416135994753 1.0 1.0 2 P31749 1
Akt phosphorylates targets in the nucleus 0.773203322499078 0.547781979559923 0.5838416135994753 1.0 1.0 2 P31749 1
Energy dependent regulation of mtor by lkb1 ampk 0.4523464159102939 0.5421848575772192 0.5876911656862629 1.0 1.0 7 Q9Y2Q5,Q6IAA8 2
Processing of smdt1 0.4449117733191566 0.5275021614041098 0.5978449158737917 1.0 1.0 10 Q96TA2,P35232,Q8NE86,O75439,Q9UJZ1 5
Mitotic telophase cytokinesis 0.4421325307112259 0.523402380978022 0.6006942676269929 1.0 1.0 11 Q7Z5K2,O95235,Q02241,Q9UQE7,Q9NTI5,Q29RF7,Q9Y6X3 7
Regulation of glycolysis by fructose 2 6 bisphosphate metabolism 0.5193797225620823 0.5158102297663553 0.6059869570601926 1.0 1.0 4 P30154 1
Sumoylation of transcription cofactors 0.4425540799277742 0.5119944466059569 0.6086548962156177 1.0 1.0 9 Q96ST3 1
Base excision repair ap site formation 0.4682461880461843 0.5028684986773675 0.6150567301251981 1.0 1.0 5 P13051,P29372,P62805 3
Rna polymerase iii transcription initiation from type 3 promoter 0.5153252400510646 0.5025728006443365 0.6152646563636051 1.0 1.0 4 P62875,O15160 2
Rna polymerase iii chain elongation 0.5153252400510646 0.5025728006443365 0.6152646563636051 1.0 1.0 4 P62875,O15160 2
Downregulation of erbb2 signaling 0.4426622392961055 0.5021057865894497 0.6155931099738159 1.0 1.0 6 P31749,Q9UNE7 2
Resolution of abasic sites ap sites 0.3882065573649105 0.495687555902299 0.6201148681700968 1.0 1.0 24 Q07864,Q9NR33,P18858,P18887,P35251,Q9UGN5,P13051 7
Transcriptional regulation by mecp2 0.4348197474062834 0.4933954568587519 0.6217331918400382 1.0 1.0 11 Q9NWH9,Q8WYQ5,Q96ST3,Q92769,P51608 5
Mtor signalling 0.4212490227743136 0.4885658059929377 0.6251491263359394 1.0 1.0 16 P31749,P23588,Q6IAA8 3
Tp53 regulates transcription of cell cycle genes 0.4248890371775501 0.4794409095924671 0.6316249960128966 1.0 1.0 14 P14635 1
Miscellaneous transport and binding events 0.5075218280033484 0.4774340523018728 0.6330530708476336 1.0 1.0 4 P35611,Q8N4V1 2
Insulin receptor recycling 0.431782753104686 0.4747073286754034 0.6349955935846823 1.0 1.0 10 Q15904,P21281,Q9Y5K8,P36543 4
Vegfr2 mediated vascular permeability 0.430932420605998 0.4713501949302404 0.6373906762258419 1.0 1.0 10 P14923,P31749,P31751 3
Dual incision in tc ner 0.3530224901942896 0.4701264198791382 0.6382646994837287 1.0 1.0 29 P05114 1
Cohesin loading onto chromatin 0.4306573714583822 0.4614338982017749 0.6444873359273566 1.0 1.0 8 Q7Z5K2,Q9Y6X3 2
Tetrahydrobiopterin bh4 synthesis recycling salvage and regulation 0.5022964924414 0.4608608769383012 0.6448984221603429 1.0 1.0 4 P31749 1
Adora2b mediated anti inflammatory cytokines production 0.4278352774327238 0.4543773946862501 0.6495572197018264 1.0 1.0 9 P04899 1
Cdc42 gtpase cycle 0.3746609172768471 0.4534982334519731 0.6501900151114408 1.0 1.0 25 Q86UP2,Q6IAA8,Q13017,Q9UQB8,P42166 5
Signaling by notch3 0.4540867459219103 0.4532072674867313 0.6503994997869529 1.0 1.0 5 Q92542 1
Transcriptional regulation of white adipocyte differentiation 0.4283786529394163 0.4528036347131658 0.6506901461151127 1.0 1.0 8 Q9Y2W1,Q71SY5,O75448 3
Rhobtb2 gtpase cycle 0.4016261101843844 0.4477402795519006 0.6543406482046925 1.0 1.0 19 P07910,P38159,P62995 3
Signaling by egfr 0.4216402747789739 0.4407816686878869 0.6593710657282044 1.0 1.0 11 P49023,P19174,O14964,Q92783 4
Triglyceride metabolism 0.4243569731018373 0.4341812814614272 0.6641568048386859 1.0 1.0 6 Q01469 1
Triglyceride catabolism 0.4243569731018373 0.4341812814614272 0.6641568048386859 1.0 1.0 6 Q01469 1
The citric acid tca cycle and respiratory electron transport 0.4078613615380468 0.429898381823839 0.667269562631235 1.0 1.0 88 P21912,P22695,Q16718,Q13423,P07954,O75947,P00846,O43837,O95168,P48735,P56385,Q16795,P36542,Q9BSH4,O75306,O95182,Q7L592,P14927,P24539,Q9NX14,P09669,O43676,P15954,O14949,Q12931,O00483,O75489,P47985,P06576,P20674 30
Transmission across chemical synapses 0.3030291175647924 0.4169215863596951 0.6767357637682232 1.0 1.0 41 P07196,P63218,P35609,Q9Y639,P04899,O75915 6
Nade modulates death signalling 0.5267341040462523 0.4167579533303178 0.6768554600135155 1.0 1.0 3 P42574,P42575 2
Base excision repair 0.3562560915483728 0.4167350184783658 0.676872237325616 1.0 1.0 27 Q07864,Q9NR33,P18858,P18887,P35251,Q9UGN5,P13051 7
Activation of the pre replicative complex 0.3937735006440103 0.4124290907146429 0.6800249444574016 1.0 1.0 19 Q14181,Q9NR33 2
Butyrate response factor 1 brf1 binds and destabilizes mrna 0.4115793576968682 0.402015141451814 0.6876728829600265 1.0 1.0 11 P31749,Q06265 2
Regulation of tp53 activity through phosphorylation 0.3589854493394316 0.4007621061364661 0.6885952805147457 1.0 1.0 26 Q9UQ84 1
Cd28 dependent pi3k akt signaling 0.5202069393163792 0.3973231538721113 0.6911291753345239 1.0 1.0 3 P31749 1
Mitochondrial translation 0.3150986696658749 0.3891798143192913 0.697143134574727 1.0 1.0 48 Q92552,Q9Y3D9,P82664,P82914,Q9H9J2,P46199,Q96E11,Q8N5N7,Q9NQ50,P49411,P82650,Q9NRX2,Q9Y2Q9,Q13084,Q9BYD2,Q9BRJ2,Q9NYK5,Q6P1L8,Q8TAE8,P52815 20
E3 ubiquitin ligases ubiquitinate target proteins 0.3941894591876176 0.3740122669855831 0.7083951897029486 1.0 1.0 16 P50542,Q14527 2
Extra nuclear estrogen signaling 0.3938492899459415 0.3627352243748975 0.7168026840404502 1.0 1.0 15 P04899,P63218,P31749 3
Leishmania infection 0.2836398153395095 0.3622057991776347 0.7171982462569386 1.0 1.0 36 P63218,Q9UQB8,P46108,P04899,Q96JJ3 5
Fatty acid metabolism 0.3220925674252886 0.3605480006579953 0.7184373674896789 1.0 1.0 53 P11310,O00767,P33527,O43772,P49748 5
Nuclear envelope breakdown 0.286472409486371 0.349903576236854 0.7264110630424159 1.0 1.0 38 P42167,P02545,P20700,P78406,P35658,P12270,Q9BTX1,Q8TEM1,Q8WUM0,P14635,P42166 11
Regulation of cytoskeletal remodeling and cell spreading by ipp complex components 0.5028283209718163 0.3475506537650447 0.728177671009056 1.0 1.0 3 P49023 1
Global genome nucleotide excision repair gg ner 0.2963315692690438 0.3423044839003731 0.7321217615137916 1.0 1.0 34 Q07864,Q9NR33,P18858,P18887,P35251,Q9UGN5,Q9BT78 7
Downstream signal transduction 0.3966509867697213 0.3407191383883911 0.7333150295219473 1.0 1.0 9 P19174,P46108,P20936 3
Signaling by pdgf 0.3966509867697213 0.3407191383883911 0.7333150295219473 1.0 1.0 9 P19174,P46108,P20936 3
Nucleotide excision repair 0.3033053096926474 0.3403261058214151 0.7336109596254552 1.0 1.0 46 Q07864,Q9NR33,P18858,P18887,P35251,P35244,Q9UGN5,P05114,Q9BT78 9
Ros and rns production in phagocytes 0.3964907098790467 0.3401684486948408 0.7337296771741721 1.0 1.0 9 P36543,Q9Y5K8,P21281 3
Establishment of sister chromatid cohesion 0.3941274824916268 0.3300816280770224 0.7413382846640302 1.0 1.0 7 Q9NTI5,Q29RF7,Q7Z5K2,Q9UQE7 4
Traf6 mediated nf kb activation 0.4575481650455235 0.3287536503595858 0.7423418990434123 1.0 1.0 4 Q7Z434 1
Signaling by met 0.3864442631946987 0.3265772753814044 0.7439876335318316 1.0 1.0 14 Q92783,P46108 2
Platelet activation signaling and aggregation 0.3162705202772407 0.3227080030611442 0.7469163906055853 1.0 1.0 53 Q9NUQ9,Q9BWS9,P63218,P31749,Q9Y6I9,P46108,P04899,O43852,P35609,O15439 10
Transcriptional regulation by ventx 0.3883618415777231 0.3219401074091519 0.747498068053656 1.0 1.0 12 Q9UJX4 1
Regulation of tp53 activity through methylation 0.4109233328341221 0.3145650340745106 0.7530919310709403 1.0 1.0 5 Q96KQ7,P04637 2
Sphingolipid de novo biosynthesis 0.3879935296640395 0.3135406823094278 0.7538699176521879 1.0 1.0 10 Q06136,O95470,P51648,O95292 4
Formation of the beta catenin tcf transactivating complex 0.3873528204865469 0.3083375890194827 0.7578254665110691 1.0 1.0 8 P51532,P16104,Q15291,P62805 4
Degradation of cysteine and homocysteine 0.4497555756297866 0.3077783178900544 0.7582510210711477 1.0 1.0 4 Q96SZ5 1
Gpcr ligand binding 0.386331716049611 0.3060358959679123 0.759577315090616 1.0 1.0 9 P63218 1
Rac1 gtpase cycle 0.2975439859998758 0.305453828877398 0.760020529829726 1.0 1.0 33 Q86UP2,Q6IAA8,Q13017,Q9UQB8,P42166 5
Hdr through homologous recombination hrr 0.3628501894412145 0.2962046426539139 0.7670738035232052 1.0 1.0 20 Q9NR33 1
Class i peroxisomal membrane protein import 0.3816691308102565 0.291179363915079 0.7709141443218714 1.0 1.0 6 P51648 1
Transcription of the hiv genome 0.3580400900371991 0.2907698763191646 0.7712273255849582 1.0 1.0 21 Q92804 1
Peroxisomal lipid metabolism 0.3806447778992158 0.289167721498425 0.772453031681599 1.0 1.0 10 Q15067 1
Role of phospholipids in phagocytosis 0.4803249829373461 0.2877397948893125 0.773545925713153 1.0 1.0 3 P19174 1
Processive synthesis on the lagging strand 0.3779858467764027 0.2861530562850372 0.7747608966338033 1.0 1.0 12 P18858 1
Signaling by braf and raf1 fusions 0.359163219433169 0.2815175619802176 0.7783134600155108 1.0 1.0 20 Q9NRY5,Q96PU8 2
Ercc6 csb and ehmt2 g9a positively regulate rrna expression 0.3765410665810833 0.2781378325172018 0.7809065549153844 1.0 1.0 11 Q13185,Q86YP4,P62805,Q92769,Q13330,Q96KQ7 6
Copi dependent golgi to er retrograde traffic 0.2912544984670647 0.2774522211225481 0.7814328881710042 1.0 1.0 45 Q9P2W9,Q14807,P61923,P49755,Q9Y678,O15260,P24390 7
Initiation of nuclear envelope ne reformation 0.3684047117778113 0.2756317839715332 0.7828308948835825 1.0 1.0 16 Q86XL3,P42167,P02545,P20700,P30153,P14635,P42166 7
Pink1 prkn mediated mitophagy 0.3749883193678005 0.2698962256363792 0.787240090968027 1.0 1.0 7 O96008,Q8N4H5 2
Signaling by erbb2 0.373820126589621 0.267317525933101 0.7892246938691727 1.0 1.0 10 P31749,P19174 2
Rhod gtpase cycle 0.3357559520142765 0.2653312258650921 0.7907543115217242 1.0 1.0 25 Q9BX68,P42167,Q5JTV8,Q13017,O15173,P20700,O95292,Q8NHP6,P51149,P42166 10
Assembly of the orc complex at the origin of replication 0.3706636122412712 0.257078887935305 0.7971178749516101 1.0 1.0 7 P52294,Q9Y619,P62805 3
Pyruvate metabolism and citric acid tca cycle 0.295351224646906 0.2554724846271912 0.7983581927589896 1.0 1.0 32 Q13423 1
Amino acids regulate mtorc1 0.3667439162149875 0.2494573036622744 0.8030070638269526 1.0 1.0 12 Q9Y2Q5,Q6IAA8 2
Met activates pi3k akt signaling 0.6569158540989548 0.2494220350001448 0.8030343421779618 1.0 1.0 2 Q9NWH9 1
Inflammasomes 0.4624277456647512 0.2442602242769553 0.8070292869963898 1.0 1.0 3 P09601,P08238 2
The nlrp3 inflammasome 0.4624277456647512 0.2442602242769553 0.8070292869963898 1.0 1.0 3 P09601,P08238 2
Purinergic signaling in leishmaniasis infection 0.4624277456647512 0.2442602242769553 0.8070292869963898 1.0 1.0 3 P09601,P08238 2
Termination of translesion dna synthesis 0.3563552704919769 0.2408585915309509 0.8096647165737776 1.0 1.0 17 Q15004,Q07864,P35251,Q9NR33 4
Esr mediated signaling 0.2726226441704014 0.2322732524070307 0.8163257858644941 1.0 1.0 40 P04899,P31749,Q13951,P63218 4
Cell extracellular matrix interactions 0.3614327062228533 0.2307421551886098 0.8175151219749386 1.0 1.0 7 P21333,Q14315,P49023,P12814,P05556,Q96AC1 6
Polb dependent long patch base excision repair 0.3593880045346617 0.2269244088017174 0.8204825216345828 1.0 1.0 6 P18858 1
Interaction between l1 and ankyrins 0.4144565571765163 0.2215321117076533 0.8246781361279703 1.0 1.0 4 Q01082 1
Acyl chain remodelling of pg 0.6424702058504841 0.2207628057169686 0.825277125779833 1.0 1.0 2 Q8NF37 1
Selective autophagy 0.3001044376010939 0.2187835702137318 0.8268186459077422 1.0 1.0 30 P08670,P50542,P54619,P19784,O96008,Q13885,Q96HS1,Q8N4H5 8
Caspase mediated cleavage of cytoskeletal proteins 0.3563215192033283 0.2167749409314279 0.8283837418475064 1.0 1.0 7 P08670,Q13813 2
P75 ntr receptor mediated signalling 0.3482427928728852 0.2026719624594332 0.8393914390719448 1.0 1.0 15 Q92769,Q92542,Q92974 3
Tbc rabgaps 0.3487764733186846 0.1956371880634628 0.8448941508207246 1.0 1.0 12 P20339,Q9Y3P9 2
Factors involved in megakaryocyte development and platelet production 0.2635979689180353 0.1929821114875987 0.8469729777142931 1.0 1.0 39 Q14807,P04637,P68371,Q92667,P20339,O95140,Q9H4M9,P10644,Q96ST3,Q9NSK0,Q13885,Q92769,P45973 13
Gap junction assembly 0.3603541674669559 0.1829060860050881 0.8548717075157193 1.0 1.0 5 Q13885 1
Transport of connexons to the plasma membrane 0.3603541674669559 0.1829060860050881 0.8548717075157193 1.0 1.0 5 Q13885 1
Rna polymerase i promoter escape 0.3439025245271846 0.1821166997954535 0.8554911433453896 1.0 1.0 12 O95602,O15160,Q9H9Y6,P62875,Q13185,P62805 6
Cd28 dependent vav1 pathway 0.3950126490784172 0.1806603678499544 0.8566341687034849 1.0 1.0 4 Q13177,P60953,P62993 3
Rna polymerase iii transcription initiation from type 1 promoter 0.3394860658704305 0.1720406614122853 0.8634055623636905 1.0 1.0 8 Q8WUA4,O15160,Q12789,O14802,P62875,Q9Y5Q9,P19388 7
Rna polymerase iii transcription 0.3396089790007318 0.170956934628438 0.8642576281917345 1.0 1.0 9 Q8WUA4,P05455,O15160,Q12789,O14802,P62875,Q9Y5Q9,P19388 8
Interleukin 7 signaling 0.6124954857349252 0.1680713954062234 0.8665271123719016 1.0 1.0 2 P51532 1
Interleukin 15 signaling 0.6124954857349219 0.1680713954062181 0.8665271123719058 1.0 1.0 2 P62993 1
Rac3 gtpase cycle 0.2939489280638523 0.1678414490703428 0.8667080133727099 1.0 1.0 29 Q13017,Q9UQB8,Q6IAA8,P42166 4
Signaling by notch1 pest domain mutants in cancer 0.3357042057555499 0.1676997657017022 0.8668194805226126 1.0 1.0 6 Q92542 1
Bile acid and bile salt metabolism 0.387061799783149 0.1653833805663157 0.8686422339342985 1.0 1.0 4 Q96SU4,P51659,P22059 3
Synthesis of bile acids and bile salts 0.387061799783149 0.1653833805663157 0.8686422339342985 1.0 1.0 4 Q96SU4,P51659,P22059 3
Resolution of ap sites via the multiple nucleotide patch replacement pathway 0.3260349801710203 0.163553408666827 0.8700827251773886 1.0 1.0 20 Q07864,Q9NR33,P18858,P35251,Q9UGN5 5
Apoptosis induced dna fragmentation 0.3356701225828472 0.1604054932411205 0.872561662670523 1.0 1.0 10 P26583,P09429,Q14974,P07305,P52294 5
Egr2 and sox10 mediated initiation of schwann cell myelination 0.3841259016932294 0.1599565091981604 0.8729153336380486 1.0 1.0 4 Q92769,P46939 2
Intrinsic pathway for apoptosis 0.3210609366544315 0.1558684119857387 0.8761367445284929 1.0 1.0 21 Q9NR28,P31749 2
Meiotic synapsis 0.3328955511954852 0.1557638749954367 0.8762191465767897 1.0 1.0 14 Q9UH99,O94901,P02545,P16104,P20700,Q9UQE7,P62805 7
Costimulation by the cd28 family 0.33304133815827 0.1537114123522243 0.877837285973111 1.0 1.0 12 P30154,P31749,P30153 3
Detoxification of reactive oxygen species 0.3318461829251821 0.1523510927519847 0.8789100290188767 1.0 1.0 9 P32119,P07237,P04179 3
Sealing of the nuclear envelope ne by escrt iii 0.3310734364074962 0.1505622547112145 0.8803210382638345 1.0 1.0 9 Q13885,P53990 2
Opioid signalling 0.3281169327079946 0.1482230609460875 0.8821667328323093 1.0 1.0 16 P30154,P63218,P04899,P62136 4
Met activates ptk2 signaling 0.5976886962802431 0.1454642276658277 0.8843443574872853 1.0 1.0 2 Q9NWH9 1
Met interacts with tns proteins 0.5976886962802431 0.1454642276658277 0.8843443574872853 1.0 1.0 2 Q9NWH9 1
Runx2 regulates bone development 0.3752891616835761 0.1443239839325011 0.8852446401314309 1.0 1.0 4 Q13951 1
Processing of intronless pre mrnas 0.3274485523893918 0.1436203058799964 0.8858003051219816 1.0 1.0 15 O43809,Q8N684,Q92989 3
Response of mtb to phagocytosis 0.3286243389903209 0.1428525345037256 0.8864066459733466 1.0 1.0 12 P20339,O14964 2
Infection with mycobacterium tuberculosis 0.3286243389903209 0.1428525345037256 0.8864066459733466 1.0 1.0 12 P20339,O14964 2
Wnt mediated activation of dvl 0.5951607078367597 0.1418302917693862 0.8872140565576485 1.0 1.0 2 P19784 1
Activation of smo 0.5947995666305557 0.1413165126303841 0.8876199053286224 1.0 1.0 2 Q9Y496 1
Interleukin 12 family signaling 0.285081533924215 0.1323784875425394 0.8946849293717278 1.0 1.0 29 P51809,P07355,O14979,P20700,P07237,P27824,P04179,Q53EL6 8
Telomere extension by telomerase 0.3225923244026126 0.131689040574542 0.8952302543738169 1.0 1.0 9 Q9NX24,Q9Y265,P24941,Q9Y230,Q9BUR4,Q9NY12,O60832,O15084 8
Activation of ampk downstream of nmdars 0.318571259284492 0.1280274414080714 0.8981272566354783 1.0 1.0 7 Q13885,P54619 2
Insertion of tail anchored proteins into the endoplasmic reticulum membrane 0.3209713461506407 0.1266317584890191 0.8992318596385613 1.0 1.0 10 Q13190,Q9P0L0,P51648 3
Signaling by notch1 0.3162081194712355 0.1233440795086715 0.9018346369009892 1.0 1.0 7 Q92542 1
Meiotic recombination 0.3172763491488595 0.1188178705354255 0.9054196503405694 1.0 1.0 10 P49959,P15927,P24941,P16104,P35244,Q92878,O60934,P62805,P11802 9
Mitotic prophase 0.2795308599487772 0.1178533853081977 0.9061838288893392 1.0 1.0 53 P42695,P42167,P02545,P20700,P78406,P35658,P12270,O60763,Q9BTX1,Q8TEM1,P30153,Q8WUM0,P30154,P14635,Q01105,P42166 16
Parasite infection 0.308158043718926 0.1171589051608154 0.9067341315157572 1.0 1.0 21 Q9UQB8,P46108 2
Dual incision in gg ner 0.3099649326757573 0.1162611397399234 0.907445582703022 1.0 1.0 20 Q07864,P35251,Q9UGN5,Q9NR33 4
Transport of mature transcript to cytoplasm 0.2873043481450721 0.1144016590527114 0.9089193988977052 1.0 1.0 57 Q13247,P78406,Q9BTX1,Q8WUM0,O00148,O75152,Q8TEM1,P26368,Q9UBU9,Q96FV9,P84103,Q13243,Q9Y5S9,Q16629,Q9C0J8,Q86V81,P82979,Q13242,P35658,P12270,Q07955,Q8N1F7 22
Cytochrome p450 arranged by substrate type 0.3922075876832063 0.1126600591647289 0.910300067755397 1.0 1.0 3 P22570 1
Flt3 signaling in disease 0.3502214002674175 0.1057209670465109 0.9158037442812764 1.0 1.0 4 Q14789 1
Pcna dependent long patch base excision repair 0.3096297904003854 0.1039605181384407 0.9172006807005656 1.0 1.0 17 Q9NR33,Q07864,P35251,P18858 4
G alpha i signalling events 0.3044260885945177 0.1015583568084044 0.9191072349306452 1.0 1.0 20 P04899,P63218 2
Epigenetic regulation of gene expression 0.2410737980114149 0.1000568579295353 0.9202991857743472 1.0 1.0 37 O95602,O15160,Q9H9Y6,Q96T88,P35659,O60264,Q15022,O00422,P62875,Q96ST3,Q13185,P62805,Q92769,Q13330,Q96KQ7 15
Protein ubiquitination 0.2924958990345871 0.0945541036934589 0.9246690063777644 1.0 1.0 24 P50542,Q14527 2
Translesion synthesis by y family dna polymerases bypasses lesions on dna template 0.3009579449461688 0.0927743860141241 0.9260828002291768 1.0 1.0 20 Q15004,Q07864,P35251,Q9NR33 4
Interleukin 12 signaling 0.2855595958579667 0.0925722807645021 0.9262433659078444 1.0 1.0 26 P51809,P07355,O14979,P20700,P07237,P04179,Q53EL6 7
Processing of capped intronless pre mrna 0.3046444515932736 0.0924222789980486 0.9263625391014424 1.0 1.0 17 O43809,Q8N684,Q92989 3
Prc2 methylates histones and dna 0.3388469914878226 0.0909716536599778 0.9275151147411228 1.0 1.0 4 Q15022,P62805 2
Meiosis 0.2947356985427024 0.0868856973951939 0.9307623683485676 1.0 1.0 22 Q9UH99,O94901,P02545,P16104,P20700,P35244,Q92878,O60934,Q9UQE7,P62805 10
Reproduction 0.2947356985427024 0.0868856973951939 0.9307623683485676 1.0 1.0 22 Q9UH99,O94901,P02545,P16104,P20700,P35244,Q92878,O60934,Q9UQE7,P62805 10
Chromosome maintenance 0.2424276047662859 0.0864625294088288 0.9310987416872268 1.0 1.0 39 P46100,Q14181,P18858 3
Rhob gtpase cycle 0.3002691623641424 0.084697639969605 0.9325017722585228 1.0 1.0 18 Q13017,O75116 2
Sumoylation of transcription factors 0.3324900614383765 0.0834608641947655 0.933485094631453 1.0 1.0 4 Q13330,Q12888,P04637 3
Diseases associated with n glycosylation of proteins 0.3688583815028963 0.083084822516548 0.9337840939941242 1.0 1.0 3 Q13724,O75340 2
Tristetraprolin ttp zfp36 binds and destabilizes mrna 0.2985860964130148 0.0814542936592615 0.9350806724162796 1.0 1.0 11 Q96B26,Q92973,Q15024,Q06265 4
Fcgamma receptor fcgr dependent phagocytosis 0.2772021953171765 0.0778219055350668 0.9379697211933028 1.0 1.0 27 Q8IV08,O15511,Q9UQB8,P16333,P46108,P19174,Q96JJ3 7
Cytoprotection by hmox1 0.2890650590094831 0.0762843501622867 0.9391928763227644 1.0 1.0 62 P30519,O00231,P49721,O00483,P33527,Q96ST3,P15954,P20674,P28074 9
Regulation of tp53 activity through acetylation 0.293653833268226 0.0752935496049995 0.9399811535855528 1.0 1.0 10 Q92769,P31749 2
Dna methylation 0.323060659408816 0.0732607023208975 0.941598662637652 1.0 1.0 4 Q96T88,P62805 2
Rho gtpases activate iqgaps 0.2919232162260058 0.0725373460598645 0.94217428587592 1.0 1.0 10 P60953,P04350,P68371,P35222,P63000,Q9BVA1,P46940,P35221,Q13885 9
Recognition and association of dna glycosylase with site containing an affected purine 0.3220093964582519 0.0721917084514701 0.9424493436550698 1.0 1.0 4 P16104,P29372,P62805 3
Trans golgi network vesicle budding 0.237835736051411 0.069470283934269 0.9446152854760042 1.0 1.0 35 Q8NBS9,P51809,Q8NC96,P55327,O14964,P09496,Q10567,Q14789,Q92538,Q9H3P7 10
Hdacs deacetylate histones 0.2875834174337378 0.0658798756485944 0.947473462676362 1.0 1.0 10 O00422,Q86YP4,P62805,Q92769,Q13330 5
Inla mediated entry of listeria monocytogenes into host cells 0.5225713253882329 0.0641921782687663 0.9488172053887292 1.0 1.0 2 O60716 1
Fgfr2 alternative splicing 0.2894908790494551 0.0628902973985048 0.9498538611052983 1.0 1.0 13 P09651,P52272,P62875,P31943,Q01085,P26599 6
Rhoq gtpase cycle 0.2889365552934483 0.0609094970076946 0.9514312859727136 1.0 1.0 18 Q6IAA8,Q15758,Q13017,Q14155,P14923,Q14160 6
Transferrin endocytosis and recycling 0.2831282105734282 0.0569176714160223 0.9546107773779692 1.0 1.0 11 Q15904,P21281,Q9Y5K8,P36543 4
Death receptor signalling 0.2783994652789942 0.0523604963228752 0.9582414502827346 1.0 1.0 23 O95429,Q92974 2
Mrna splicing minor pathway 0.2600192560425493 0.0488549850888912 0.961034862689301 1.0 1.0 29 Q13435,Q13247,Q9Y333,Q07955,Q86XP3,Q16629 6
Hsf1 activation 0.2807160813512875 0.0465065267204357 0.9629065321462004 1.0 1.0 15 P04792,P50454,O75190 3
Attenuation phase 0.2765013299462193 0.0454274389402018 0.9637666104469232 1.0 1.0 12 P04792,P50454 2
Neuronal system 0.2554089697993188 0.0433498111748225 0.9654226849393056 1.0 1.0 50 P04899,P63218,Q9Y639,P35609 4
Rab regulation of trafficking 0.2537442734119358 0.0418047662769308 0.9666543353968926 1.0 1.0 30 P31749,P20339,Q9Y3P9,Q7Z392 4
Propionyl coa catabolism 0.3175578034682126 0.0404473142308505 0.967736509787926 1.0 1.0 3 P22033,P05165 2
Apoptotic execution phase 0.2586227517247639 0.0359061853737235 0.9713571638344074 1.0 1.0 28 P26583,Q07157,P35611,P08670,Q14974,P02545,P09429,P15924,P20700,Q13813,P07305,P52294 12
Wax and plasmalogen biosynthesis 0.3081647398843994 0.0354804267083282 0.9716966537715556 1.0 1.0 3 O00116,Q8WVX9 2
Synthesis of ip2 ip and ins in the cytosol 0.4665944384254321 0.0341661164051695 0.972744685949 1.0 1.0 2 Q01968 1
Recognition of dna damage by pcna containing replication complex 0.2736519510598659 0.0341335164036187 0.9727706818241736 1.0 1.0 17 Q07864,P35251,Q9NR33 3
Oncogenic mapk signaling 0.26630264526178 0.030491268549371 0.9756752568332828 1.0 1.0 24 Q96PU8 1
Carboxyterminal post translational modifications of tubulin 0.2372513562386893 0.0272785901605962 0.978237533090376 1.0 1.0 6 P04350,P68371,Q9BUF5,Q9BVA1,Q13885 5
Translation of sars cov 2 structural proteins 0.2603647023440534 0.0236573746714722 0.9811259065652316 1.0 1.0 13 P04844,P04843,P14314 3
Mitochondrial calcium ion transport 0.263721798373637 0.0231380968785557 0.9815401168982358 1.0 1.0 15 Q96TA2,P35232,Q92667,Q8NE86,O75439,Q9UJZ1,O95202 7
Chl1 interactions 0.4131455399061071 0.0213546031922106 0.9829627867030856 1.0 1.0 2 P05556 1
Gaba synthesis release reuptake and degradation 0.413145539906101 0.0213546031922098 0.9829627867030865 1.0 1.0 2 P51649 1
Ion channel transport 0.2639295830170639 0.0208429453652804 0.9833709397226976 1.0 1.0 22 P35670 1
Sumoylation of chromatin organization proteins 0.2422505047822149 0.0208125266767031 0.9833952050610156 1.0 1.0 31 Q15022,P78406,P35658,P12270,Q9BTX1,Q8TEM1,P62805,Q8WUM0,Q92769,P45973 10
Interactions of vpr with host cellular proteins 0.233647509438121 0.0199090674670191 0.984115911786916 1.0 1.0 33 O75475,P05141,P17096,P78406,P52948,P35658,P12270,P49792,Q9BTX1,Q8TEM1,Q8WUM0,P12235,P52294,Q8N1F7 14
Apoptotic cleavage of cellular proteins 0.2634188025604566 0.0197640296810004 0.9842316124313268 1.0 1.0 17 Q07157,P08670,P20700,P02545 4
Diseases of programmed cell death 0.2637044282353865 0.0191962910010377 0.9846845164111636 1.0 1.0 18 P32119,Q14181,P04637,P02545,P20700,Q15022,P07384,P62805,P04179 9
Translation of replicase and assembly of the replication transcription complex 0.3950884795955228 0.0191911883973781 0.9846885869499816 1.0 1.0 2 Q8WUX9 1
Synthesis of bile acids and bile salts via 7alpha hydroxycholesterol 0.3867822318526567 0.0184422577107597 0.9852860413885548 1.0 1.0 2 P51659 1
Shc related events triggered by igf1r 0.375947995666306 0.0176545179238336 0.9859144644252802 1.0 1.0 2 P62993 1
Grb2 sos provides linkage to mapk signaling for integrins 0.3600577825929942 0.0168129518412782 0.9865858372828218 1.0 1.0 2 P62993 1
Positive epigenetic regulation of rrna expression 0.2546384990987305 0.0149873186906817 0.9880422974665176 1.0 1.0 26 O95602,O15160,Q9H9Y6,P35659,O60264,P62875,Q13185,Q9NR30,Q86YP4,Q92769,Q13330,P62805,Q96KQ7 13
Formation of incision complex in gg ner 0.2434782608695675 0.0140966292352794 0.9887528896698804 1.0 1.0 11 Q13620,P54727,P27694,P15927,P61088,Q86WJ1,P35244,Q9UGN5,P18074,P09874 10
Rhoh gtpase cycle 0.2477659218706951 0.0063667483849987 0.994920104080457 1.0 1.0 15 O75116 1
Ephb mediated forward signaling 0.2409435576400988 0.0032542917678921 0.9974034554251324 1.0 1.0 14 O75116,P20936,O15511 3