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Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
Familial partial lipodystrophy fpld 0.9096060389006924 2.492470309985552 0.0126857935947031 0.9994365488722056 0.9943134379330631 7 O75844,O60725 2
Acquired partial lipodystrophy barraquersimons syndrome 0.9130494609231012 2.367107437393802 0.0179277276787366 0.9999751079104232 0.9943134379330631 5 O60725 1
Cholesterol biosynthesis with skeletal dysplasias 0.9044333038574311 2.333127818913192 0.0196414377944875 0.9999910550384375 0.9943134379330631 5 Q15392,Q16850,Q14739 3
Cholesterol biosynthesis pathway 0.8044008929022778 2.019499098679613 0.0434353708956853 0.9999999999950044 0.9943134379330631 9 Q16850,P48449,P37268 3
Progeriaassociated lipodystrophy 0.7970519386457238 1.9693104314838832 0.0489174540348757 0.999999999999828 0.9943134379330631 10 P49354,P46063,O75844,O60725 4
Sphingolipid metabolism overview 0.772650674703524 1.924218594053854 0.0543271893934718 0.999999999999994 0.9943134379330631 7 Q96G23,P27544,Q06136 3
Sphingolipid metabolism integrated pathway 0.772650674703524 1.924218594053854 0.0543271893934718 0.999999999999994 0.9943134379330631 7 Q96G23,P27544,Q06136 3
Ketogenesis and ketolysis 0.7864248256844164 1.854984916533555 0.0635983805400868 1.0 0.9943134379330631 5 O43772,P23786 2
Methionine metabolism leading to sulfur amino acids and related disorders 0.8212017397247742 1.851723656908469 0.0640655151491094 1.0 0.9943134379330631 4 P55263 1
Cellular proteostasis 0.811783960720129 1.8139275879965469 0.0696888747497013 1.0 0.9943134379330631 4 Q9UHV9,P61758,Q99471 3
Constitutive androstane receptor pathway 0.7683781373969086 1.7798942358901657 0.0750932712101648 1.0 0.9943134379330631 5 P08183 1
Statin inhibition of cholesterol production 0.9083844580777044 1.7764783996237512 0.0756540990796719 1.0 0.9943134379330631 3 Q8WTV0,P37268 2
Transcriptional activation by nrf2 in response to phytochemicals 0.9071345548695906 1.7717973332643009 0.0764282054094107 1.0 0.9943134379330631 3 P09601 1
Oxidation by cytochrome p450 0.7935883953884508 1.7405888182310996 0.0817556790562492 1.0 0.9943134379330631 4 Q16850,O43169 2
Influence of laminopathies on wnt signaling 0.741074532809358 1.726849500840231 0.0841946957565271 1.0 0.9943134379330631 10 O75844,O60725 2
Vitamin d metabolism 0.8879345603272015 1.6997033456331234 0.0891867397279937 1.0 0.9943134379330631 3 Q9UBM7,P38435 2
Vitamin dsensitive calcium signaling in depression 0.7064808170866819 1.659996642184759 0.0969151280362101 1.0 0.9943134379330631 6 Q8NB78,P48506 2
Cholesterol metabolism with bloch and kandutschrussell pathways 0.7531131808210788 1.646934833016799 0.0995714412257591 1.0 0.9943134379330631 18 Q15392,Q16850,P48449,Q14739,Q9BWD1,P37268 6
Eicosanoid metabolism via lipooxygenases lox 0.7241403225311972 1.5939640351055848 0.1109440904661234 1.0 0.9943134379330631 5 P09960,Q8N8N7 2
1q211 copy number variation syndrome 0.6720149242859792 1.485875615980034 0.1373120244242485 1.0 0.9943134379330631 7 Q9NPH0 1
Gammaglutamyl cycle for the biosynthesis and degradation of glutathione including diseases 0.8209566432274258 1.445947070849965 0.1481920480036791 1.0 0.9943134379330631 3 O75223 1
Neural crest cell migration in cancer 0.6882338881083538 1.441476543375489 0.1494500994643739 1.0 0.9943134379330631 5 P61586 1
Pentose phosphate metabolism 0.6776530031039958 1.3963508448562627 0.1626088696444867 1.0 0.9943134379330631 5 P11413 1
Nrf2are regulation 0.6450361038016403 1.38928994768325 0.1647445993987917 1.0 0.9943134379330631 6 P09601 1
Overlap between signal transduction pathways contributing to lmna laminopathies 0.6847749915018204 1.3686467303213432 0.1711097291895278 1.0 0.9943134379330631 16 Q9Y2U8,P55209,O75844,O60725,P49354,Q9UPY3 6
15q112 copy number variation syndrome 0.6967804982570441 1.3450861658335078 0.1785974102075547 1.0 0.9943134379330631 4 Q9BSJ2,Q7L576 2
Eicosanoid synthesis 0.9509403107113664 1.333301539370611 0.1824328687331919 1.0 0.9943134379330631 2 Q9H7Z7 1
Cysteine and methionine catabolism 0.6264750484825367 1.3068546987289018 0.1912620639841726 1.0 0.9943134379330631 6 P48637,P48506,Q99707,P25325 4
Sphingolipid pathway 0.6364726571203253 1.305723502247914 0.1916466026181034 1.0 0.9943134379330631 8 O95470,Q96G23,Q06136 3
Glycosylation and related congenital defects 0.6558364117430713 1.3031451838748505 0.1925252002498185 1.0 0.9943134379330631 5 O75352 1
Photodynamic therapyinduced nfe2l2 nrf2 survival signaling 0.6864210983108385 1.3024715446547777 0.1927552391738094 1.0 0.9943134379330631 4 P09601,P07099 2
Myometrial relaxation and contraction pathways 0.6611951429603615 1.2964018365693686 0.1948370796783045 1.0 0.9943134379330631 14 Q99439,P61981,Q05682,Q04917,P10644,P78417,P63104,P27348,P17612,P0DP25 10
Metabolism of spingolipids in er and golgi apparatus 0.9403107113654956 1.2940039575143427 0.1956640538274743 1.0 0.9943134379330631 2 Q06136 1
Wnt signaling pathway 0.6249910210516653 1.27706154405382 0.2015805202099601 1.0 0.9943134379330631 7 P61586 1
Ciliopathies 0.6404064992477566 1.2600234191237414 0.2076609140980645 1.0 0.9943134379330631 11 O43924,Q15555,Q10713 3
Antiviral and antiinflammatory effects of nrf2 on sarscov2 pathway 0.923957481602617 1.233657770509723 0.2173304561413256 1.0 1.0 2 P09601 1
Nucleotidebinding oligomerization domain nod pathway 0.6646255571565707 1.2128468825345289 0.2251883670759307 1.0 1.0 4 Q13685 1
Aryl hydrocarbon receptor pathway wp2873 0.6339708884958992 1.2096631626153194 0.2264081705742593 1.0 1.0 5 O00170,P07900 2
Nanomaterial induced apoptosis 0.6567028812702169 1.1803103813903058 0.2378767906928733 1.0 1.0 4 Q9NR28 1
Eicosanoid metabolism via cyclooxygenases cox 0.6251740322188584 1.1720828278512854 0.2411638035678862 1.0 1.0 5 Q8N8N7 1
Spinal cord injury 0.6302053936525418 1.1388111581578224 0.2547819268224667 1.0 1.0 15 P08670,P06493,Q9NQC3,P61586,P11802,P14174 6
Sphingolipid metabolism in senescence 0.6064822375955343 1.128799576749438 0.2589823912527351 1.0 1.0 10 Q96G23,Q06136 2
Nephrotic syndrome 0.6034336822859994 1.0945514968031878 0.2737131748142958 1.0 1.0 11 Q9Y5K6,O75844,Q9NQW6,Q14108,P54577 5
Apoptosis 0.5820068326844883 1.085804019655276 0.2775657076402655 1.0 1.0 7 Q9NR28 1
Aryl hydrocarbon receptor pathway wp2586 0.5795890766750484 1.0750758108968566 0.2823407882223683 1.0 1.0 7 P48506 1
Glutathione metabolism 0.5705896435341301 1.0585108588881085 0.2898226028100708 1.0 1.0 6 P48506,P11413 2
Striated muscle contraction pathway 0.6264202432112513 1.056417247677111 0.2907776294764939 1.0 1.0 4 P08670 1
Complement system in neuronal development and plasticity 0.5625447679764828 1.0229270873130605 0.3063423211487612 1.0 1.0 6 Q5KU26,Q9NR28 2
Mirna biogenesis 0.7084691917654 1.0181835077430064 0.3085907555737099 1.0 1.0 3 Q9UPY3 1
Oxysterols derived from cholesterol 0.5548054685125356 0.9655351334209704 0.3342768474166075 1.0 1.0 7 Q9UBM7,P34913 2
Exrna mechanism of action and biogenesis 0.6920905326745588 0.956752333223708 0.3386922766469689 1.0 1.0 3 Q9UPY3 1
Mevalonate arm of cholesterol biosynthesis pathway 0.5578536719446956 0.9563669214711672 0.3388868905743383 1.0 1.0 8 Q9BWD1 1
Intracellular trafficking proteins involved in cmt neuropathy 0.5689720048169226 0.933772203954678 0.3504214105476335 1.0 1.0 5 Q9NR77 1
Wnt signaling pathway and pluripotency 0.5675537218115616 0.9151834978031254 0.3600953063794101 1.0 1.0 12 Q15257,P61586 2
Metapathway biotransformation phase i and ii 0.5929901266720585 0.9052701496703922 0.3653222862833774 1.0 1.0 19 P78417,Q16850,P07099,Q86UY6 4
Joubert syndrome 0.5574377414041451 0.851389654655796 0.3945529366353051 1.0 1.0 13 O43924,P61586 2
Mammary gland development pathway pregnancy and lactation stage 3 of 4 0.5751580480763737 0.8501948431613295 0.3952167683079155 1.0 1.0 4 P06753,P61201 2
Pentose phosphate pathway in senescent cells 0.5447231965396997 0.8328838067911801 0.4049102631383428 1.0 1.0 5 P11413 1
Extracellular vesicles in the crosstalk of cardiac cells 0.6511247443762797 0.8055804765477773 0.4204847865255914 1.0 1.0 3 P04792,P40763 2
Mitochondrial complex iii assembly 0.5314378956502018 0.7784286835334419 0.4363163344877869 1.0 1.0 5 O14949 1
Netrinunc5b signaling pathway 0.528881860836464 0.766853059286516 0.443168885327091 1.0 1.0 11 Q92859,P61586 2
G protein signaling pathways 0.5140115908875683 0.7660561121525409 0.4436429153531331 1.0 1.0 8 P10644,P61586 2
Cell migration and invasion through p75ntr 0.7886345053148051 0.7491426785210443 0.4537712139054828 1.0 1.0 2 P61586 1
Ferroptosis 0.559323339267385 0.7410972540986734 0.4586344744199722 1.0 1.0 20 P09601,P45880,P48506,P16435,P37268 5
Vasopressinregulated water reabsorption 0.5274733737655398 0.7219959246606273 0.4702969831076402 1.0 1.0 13 Q13409,Q14203,P20339,Q9UJW0,P17612 5
Nitric oxide metabolism in cystic fibrosis 0.512576149483229 0.7024063575709403 0.4824257816379429 1.0 1.0 5 O14744,O60678 2
Inclusion body myositis 0.7665576451349181 0.6749508304386365 0.4997070045742158 1.0 1.0 2 P05067 1
Histone modifications 0.4907535430238659 0.6681516871177476 0.5040367712942637 1.0 1.0 8 Q9H7B4,O15047 2
Sterol regulatory elementbinding proteins srebp signaling 0.5466005871227654 0.6439993700089844 0.5195758425156198 1.0 1.0 23 Q8WTV0,Q16850,P48449 3
Hif1a and pparg regulation of glycolysis 0.6023082822115561 0.6326310802485953 0.5269745858993793 1.0 1.0 3 P00338 1
Mitochondrial long chain fatty acid betaoxidation 0.5007177392715061 0.6288192900850977 0.5294673697322958 1.0 1.0 12 O43772,P49748 2
Estrogen receptor pathway 0.7485690923957515 0.6161375865214402 0.5378037168935808 1.0 1.0 2 P40763 1
Male infertility 0.5142958370992955 0.5807485454089711 0.561409938409178 1.0 1.0 18 Q15165,P41440,P34896,P08183 4
Folate metabolism 0.4888368438424911 0.5803634670172508 0.5616695360594641 1.0 1.0 12 P41440,Q8WTV0,P34896,P00374 4
Vitamin b12 disorders 0.5858676633500486 0.5768990620199056 0.5640076442680539 1.0 1.0 3 Q99707 1
Envelope proteins and their potential roles in edmd physiopathology 0.5011351376446795 0.5763247654194514 0.5643956864216664 1.0 1.0 15 Q9Y2U8,Q14739,P61586 3
Wnt signaling 0.4670743820816925 0.5717201788526214 0.567511561516941 1.0 1.0 8 P61586 1
Adipogenesis 0.4900369261119417 0.5489652145433352 0.5830293220853084 1.0 1.0 14 O75844 1
Praderwilli and angelman syndrome 0.4897795402389727 0.5297601944680602 0.5962782070291779 1.0 1.0 4 P11802 1
Proteasome degradation 0.5538647842639849 0.5271349326801799 0.5980998897511474 1.0 1.0 41 Q9UL46,P01889,O43242,P10321,P60900,P62191,P25786,P49721,P28072,P25789,Q99460,O00231,P28074,Q99436,P51665,P25787,P28070,O14818,P20618,Q15008 20
Melanoma 0.4551368597396829 0.4855807304323798 0.6272644614362255 1.0 1.0 10 P62993,P11802,P0DP25 3
Hijack of ubiquitination by sarscov2 0.4541551985233034 0.4808063517190243 0.6306541355099955 1.0 1.0 5 Q13951,Q8TBC4 2
Calcium regulation in cardiac cells 0.4801117697386681 0.4604501971532792 0.6451931111945042 1.0 1.0 17 P61981,Q04917,P10644,P63104,P27348,P17612,P0DP25 7
Amyotrophic lateral sclerosis als 0.4225971431864897 0.4221386167751668 0.6729238425685482 1.0 1.0 7 Q9BUN8,P20339 2
Glucuronidation 0.4329233631813882 0.4074717835523151 0.6836615139767006 1.0 1.0 5 P36871,Q16851 2
Il10 antiinflammatory signaling pathway 0.4483139324710466 0.3933089988637425 0.6940912725829709 1.0 1.0 4 P09601,P40763 2
Genes related to primary cilium development based on crispr 0.4231741604275255 0.3754416935306389 0.707332001890032 1.0 1.0 5 Q10713 1
Type i collagen synthesis in the context of osteogenesis imperfecta 0.4343585918028739 0.373663505570534 0.7086546800034621 1.0 1.0 12 Q96AY3,O15460,P07237,O75718 4
Splicing factor nova regulated synaptic proteins 0.4383685368403117 0.3711521633741724 0.7105242004891812 1.0 1.0 13 Q92859 1
16p112 distal deletion syndrome 0.4162437690459457 0.3533615558322509 0.7238174031437592 1.0 1.0 5 Q99873,P20339 2
Camkk2 pathway 0.402115383292139 0.3505334358531177 0.7259384017278805 1.0 1.0 7 P09601 1
Apoptosis modulation and signaling 0.4121112507458743 0.3485200730163938 0.727449641568207 1.0 1.0 9 O95831,Q9H0E2,P49327,O00273,Q9NR28 5
Apoptosis modulation by hsp70 0.6565821749795647 0.34700185773103 0.7285899231221364 1.0 1.0 2 O95831 1
Liver x receptor pathway 0.6565821749795647 0.34700185773103 0.7285899231221364 1.0 1.0 2 O00767 1
Nicotine effect on dopaminergic neurons 0.5071013887123828 0.3362145480510757 0.7367090830856671 1.0 1.0 3 Q00535 1
Nonsmall cell lung cancer 0.4127474002810992 0.3334484378371706 0.7387958050119936 1.0 1.0 10 P62993,P11802,P40763 3
Purine metabolism 0.3926871075052145 0.3193661918001 0.7494488445591136 1.0 1.0 7 P00491,P00492,P07741 3
Dopamine metabolism 0.6430907604251905 0.3131605577974146 0.7541586826493252 1.0 1.0 2 P17612 1
Hippo signaling regulation pathways 0.4113418883502843 0.3122491554343634 0.7548511775843911 1.0 1.0 11 P61586 1
Glycogen synthesis and degradation 0.4271384141672888 0.3018785636333782 0.762744637603451 1.0 1.0 15 P13807,P06737,P52789,Q16851,Q15257,P36871,P0DP25 7
Transcription factors regulate mirnas related to cardiac hypertrophy 0.6316434995911763 0.2857926926447405 0.775036905236242 1.0 1.0 2 P40763 1
Nsp1 from sarscov2 inhibits translation initiation in the host cell 0.4119415140180994 0.2828647306597558 0.7772805317220599 1.0 1.0 13 P55010,O75822,O15372,P20042,P05198,P60228,O75821,P55884 8
7oxoc and 7betahc pathways 0.3804827294387514 0.2643882656614355 0.7914807525812277 1.0 1.0 8 Q9UBM7,P34913 2
Microtubule cytoskeleton regulation 0.4039963268383484 0.2582336099005497 0.796226620385101 1.0 1.0 13 Q9Y281,P06493,P40763,P16949,Q15691,P17612 6
Apoptosisrelated network due to altered notch3 in ovarian cancer 0.4129509535660735 0.2568525281206535 0.797292618382907 1.0 1.0 15 P16989,P48506,P05067 3
Familial hyperlipidemia type 4 0.6165167620605143 0.2516119688006722 0.8013410064429218 1.0 1.0 2 P49327 1
Alzheimers disease 0.4519780041263743 0.2382947014484277 0.8116525306344597 1.0 1.0 74 Q00535,P25787,P28070,P49721,P51665,P45880,Q9NQC3,P20618,P28072,O43242,O95197,P28074,P60900,Q99436,P05067,P21796,P0DP25 17
Regulation of actin cytoskeleton 0.4432237924709259 0.2375877288502327 0.8122008689848097 1.0 1.0 24 Q9UQB8 1
Alzheimers disease and mirna effects 0.4465073481245353 0.2263964922291587 0.8208930559095771 1.0 1.0 75 Q00535,P25787,P28070,P49721,P51665,P45880,Q9NQC3,P20618,P28072,O43242,O95197,P28074,P60900,Q99436,P05067,P21796,P0DP25 17
Fluoropyrimidine activity 0.3747775245960909 0.1893462169056412 0.8498214745550849 1.0 1.0 12 Q99808,Q9BZX2,P00374 3
Disruption of postsynaptic signaling by cnv 0.3366093366093415 0.1757296733406313 0.86050632210227 1.0 1.0 6 P27361,Q06787,P61981,Q07157,Q7L576 5
4hydroxytamoxifen dexamethasone and retinoic acids regulation of p27 expression 0.3366093366093351 0.1757296733406161 0.860506322102282 1.0 1.0 6 P27361,Q02750,P42345,Q96KB5,P06730 5
Pdgf pathway 0.3564227321476781 0.1693629575421824 0.8655111581602462 1.0 1.0 10 P62993,P40763,P61586 3
Ras signaling 0.3832092363723914 0.1604362068084942 0.8725374700968338 1.0 1.0 16 P17612,P0DP25,P20339,P61586 4
Small cell lung cancer 0.3353625356402119 0.1590876148609643 0.8735998458595264 1.0 1.0 7 P63208,P11802 2
Pancreatic adenocarcinoma pathway 0.3761983310184049 0.1549077462028397 0.8768940467807722 1.0 1.0 15 P11802,P30086,P61586 3
Glucocorticoid receptor pathway 0.350486734783034 0.1547795144265662 0.8769951416879229 1.0 1.0 4 P07900 1
Mfap5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement 0.3364715513712661 0.1485476331948058 0.8819105970521566 1.0 1.0 5 P12814,P27361,P18206,Q07157 4
Transsulfuration pathway 0.323644351294021 0.1459043447863396 0.8839969016540574 1.0 1.0 6 Q99707,P25325 2
Peroxiredoxin 2 induced ovarian failure 0.5588716271463705 0.1434728100702 0.8859167834938451 1.0 1.0 2 P32119 1
G13 signaling pathway 0.3549588759589328 0.140624173433877 0.8881668503635938 1.0 1.0 12 Q9Y281,Q13576,P61586 3
Genes controlling nephrogenesis 0.3210483210483166 0.1402987727112372 0.8884239339692623 1.0 1.0 6 Q9Y5K6,P11047,P35222,Q12948,O94813 5
Nocgmppkg mediated neuroprotection 0.5547833197056511 0.1371778134378967 0.8908902474216351 1.0 1.0 2 Q08752 1
3q29 copy number variation syndrome 0.3186904842880276 0.1230705599751673 0.9020512237597682 1.0 1.0 7 O95684,P61088 2
Bladder cancer 0.322144903806796 0.122569151663947 0.902448283615791 1.0 1.0 5 P28482,Q02750,P06400,P11802 4
Mechanoregulation and pathology of yaptaz via hippo and nonhippo mechanisms 0.3209169054441274 0.1205026354747094 0.9040849920527996 1.0 1.0 5 Q13177,P27348,P35222,P35221 4
Cancer immunotherapy by pd1 blockade 0.4000787564118007 0.1119500657814599 0.9108629993188 1.0 1.0 3 P40763 1
Nrf2 pathway 0.3615353369851624 0.0993907082739288 0.920828059958276 1.0 1.0 17 P09601,P11413,P28161,Q14914,O14880,P25685,P07900,P08238,P48506,P30041 10
Nucleotide metabolism 0.3314820554670997 0.0919867705015861 0.926708550634868 1.0 1.0 12 P00374,P11908,P31350,P22392,P28340 5
Exerciseinduced circadian regulation 0.3410089519804605 0.0892665696848234 0.9288700615008822 1.0 1.0 14 Q00577,Q16851,Q96PU8,P31689,P78344,P25789 6
Integrinmediated cell adhesion 0.3218905587660047 0.0654581589214286 0.9478092191969104 1.0 1.0 13 P07384,Q13464,P41240,Q15942,P62993,P18206 6
Tca cycle nutrient use and invasiveness of ovarian cancer 0.3361963190184007 0.0450752594040536 0.9640473215089592 1.0 1.0 3 P27361,P40763 2
Purine metabolism and related disorders 0.3018352189505078 0.0447441495566306 0.96431124265985 1.0 1.0 12 P00492,Q06203,P00491,O15067,P07741 5
Tcell antigen receptor tcr pathway during staphylococcus aureus infection 0.2651534234421154 0.0413837600651227 0.9669899592966544 1.0 1.0 7 P11802 1
Kallmann syndrome 0.3157464212678869 0.0327897202293419 0.9738422758747912 1.0 1.0 3 P28482,P62993 2
Translation factors 0.4032006289308218 0.030362039192871 0.9757783192239068 1.0 1.0 36 O75153,O75822,O75821,Q13144,P55010,P20042,P05198,P29692,O15371,O60841,P60842,P24534,P23588,P63241,Q9NR50,Q14232,P60228,P06730,Q04637,O15372,P55884 21
Dual hijack model of vif in hiv infection 0.3010559900026157 0.0261324102267167 0.9791517262615136 1.0 1.0 3 Q13951 1
Phosphoinositides metabolism 0.3834832379395008 0.0120507050633606 0.9903851611940542 1.0 1.0 2 Q9NTJ5 1
Fas ligand pathway and stress induction of heat shock proteins 0.2713464696223315 0.0115873403922443 0.9907548468863832 1.0 1.0 12 P04792,Q13177,P20700,Q13813,P06400,Q03252,P49327,O00273,P78527,P02545,Q9UNN5 11
Cohesin complex cornelia de lange syndrome 0.2709032474969101 0.0112095722641094 0.9910562426615634 1.0 1.0 12 Q15257 1
Hypertrophy model 0.3401471790678733 0.0071085010526398 0.9943282845257292 1.0 1.0 2 P06730 1
Ebsteinbarr virus lmp1 signaling 0.3360588716271546 0.0068498664916596 0.9945346400225036 1.0 1.0 2 P07900 1
Tolllike receptor signaling related to myd88 0.3360588716271538 0.0068498664916593 0.9945346400225036 1.0 1.0 2 Q9H0E2 1