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interpro_active_site/advanced/idx2term.json

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+{}

interpro_active_site/basic/idx2term.json

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+{}

interpro_active_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:b8d7a1d91807100691223e251550244a96d5903a69799691d962914d59e39e78
+size 64098

interpro_active_site/df_merge.tsv

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+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_50	pval_100	pval_250	pval_500

interpro_active_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2453,
+    "annotations_size": 50,
+    "title": "Average number of proteins per term",
+    "value": 2.3
+}

interpro_active_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C334/C334_val_log2fc"}

interpro_active_site/result.tsv

@@ -0,0 +1,5 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Serine carboxypeptidase, serine active site [IPR018202]	0.9832653061224488	2.1844510853271144	0.0289291178825092	0.7695659819330224	0.0628893867011071	3	Q9HB40,Q9H3G5	2
+Ubiquitin-conjugating enzyme, active site [IPR023313]	0.7787886166376339	1.415293996909455	0.1569823143742201	0.9998041902611844	0.2180309921864169	6	P49427	1
+Ubiquitin-activating enzyme E1, Cys active site [IPR033127]	0.7253849628519947	1.1881481513131145	0.2347750466586888	0.9999984531215892	0.2863110325105962	3	Q8TBC4	1
+Cysteine peptidase, cysteine active site [IPR000169]	0.6530172549227458	0.9074182683618912	0.3641856524321878	0.9999999998532708	0.423471688874637	3	P17655	1

interpro_active_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenylosuccinate synthase,  active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Cysteine peptidase, cysteine active site [IPR000169]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycoside hydrolase, family 2, active site [IPR023232]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]", "Uracil-DNA glycosylase, active site [IPR018085]"], "available_proteins": ["ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADSS", "AKT2", "APEH", "ATP5A1", "ATP5B", "ATP6V1A", "ATP6V1B2", "BLMH", "CAMK2D", "CAMK2G", "CAPN1", "CAPN2", "CDC34", "CDK1", "CDK12", "CDK2", "CDK4", "CDK5", "CDK6", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CTSA", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "EPHA7", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLUD1", "GSK3A", "GSK3B", "GSR", "GUSB", "HADHB", "HMGCL", "HMGCS1", "LDHA", "LDHB", "LONP1", "MAP2K1", "MARK2", "MDH1", "MDH2", "MTMR6", "NEK9", "NME1", "PAK2", "PBK", "PGAM1", "PKM", "PKN2", "PLK1", "PREP", "PRKACA", "PRPF4B", "PTK7", "PTPN1", "RIPK1", "RNASET2", "ROCK2", "RPS6KA1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SRPK2", "SUCLG1", "TALDO1", "TIGAR", "TOP1", "TPI1", "TPP2", "TTK", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "UMPS", "UNG", "VRK1"], "leading_proteins": ["CAPN2", "CDC34", "CPVL", "SCPEP1", "UBA3"]}

interpro_binding_site/advanced/idx2term.json

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+{}

interpro_binding_site/basic/idx2term.json

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+{"0": "EF-Hand 1, calcium-binding site [IPR018247]"}

interpro_binding_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:2084170ae3a8fcc7537bc373b637d0ad12d8657fbf83a5774cbd9752b7001f17
+size 56711

interpro_binding_site/df_merge.tsv

@@ -0,0 +1 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_50	pval_100	pval_250	pval_500

interpro_binding_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2453,
+    "annotations_size": 27,
+    "title": "Average number of proteins per term",
+    "value": 4.111111111111111
+}

interpro_binding_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C334/C334_val_log2fc"}

interpro_binding_site/result.tsv

@@ -0,0 +1,5 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+EF-Hand 1, calcium-binding site [IPR018247]	0.4669995366274244	1.1483763289934366	0.2508132412143116	0.9995889141662648	0.3721566610900477	32	Q02818,Q9Y680,P80303,Q9BRK5,Q9NWM8,Q14257,O43852	7
+Beta tubulin, autoregulation binding site [IPR013838]	0.647284226753204	0.8953518470013279	0.3705990328579616	0.9999962757402812	0.5003086943582482	4	Q9BUF5,P68371	2
+PPM-type phosphatase, divalent cation binding [IPR000222]	0.431660546715627	0.3263530009694156	0.7441572923142696	1.0	0.8735759518471861	2	Q9H0C8	1
+Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]	0.348429212566299	0.1297100739228039	0.8967958120689681	1.0	0.9505837334249464	2	P50579	1

interpro_binding_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Protein kinase, ATP binding site [IPR017441]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]", "Ureohydrolase, manganese-binding site [IPR020855]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "AKT2", "APEX1", "ARG2", "CALU", "CAMK2D", "CAMK2G", "CAPN1", "CAPN2", "CDK1", "CDK12", "CDK2", "CDK4", "CDK5", "CDK6", "COX2", "COX5B", "CSK", "CSNK1A1", "CYB5B", "DLAT", "DLST", "DST", "EHD1", "EIF2AK2", "EPHA7", "FKBP10", "FKBP14", "FKBP7", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3A", "GSK3B", "HK1", "HK2", "IDE", "ILKAP", "IQGAP1", "LETM1", "MACF1", "MAP2K1", "MARK2", "MCCC1", "METAP2", "MICU1", "MYH10", "MYH14", "MYH9", "MYO1B", "MYO1C", "NRDC", "NUCB1", "NUCB2", "PA2G4", "PAK2", "PAK4", "PC", "PCCA", "PDCD6", "PDHX", "PEF1", "PGD", "PKN2", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "PPM1G", "PRKACA", "PRKCSH", "PSAT1", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK2", "RPS6KA1", "RPS6KA3", "S100A11", "SDF4", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SRI", "SRPK1", "SRPK2", "TKT", "TTK", "TUBB", "TUBB2B", "TUBB4B", "TUBB6", "UBE3C", "UQCRC2", "VRK1"], "leading_proteins": ["CALU", "FKBP14", "FKBP7", "ILKAP", "METAP2", "NUCB1", "NUCB2", "RCN2", "SDF4", "TUBB4B", "TUBB6"]}

interpro_conserved_site/advanced/idx2term.json

@@ -0,0 +1 @@
+{}

interpro_conserved_site/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "DnaJ domain, conserved site [IPR018253]"}

interpro_conserved_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:5309d8ab2074e7846de67cc76b1f7f40d3229d4a209f590f3916782c72ecbd23
+size 106617

interpro_conserved_site/df_merge.tsv

@@ -0,0 +1 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_50	pval_100	pval_250	pval_500

interpro_conserved_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2453,
+    "annotations_size": 252,
+    "title": "Average number of proteins per term",
+    "value": 2.488095238095238
+}

interpro_conserved_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C334/C334_val_log2fc"}

interpro_conserved_site/result.tsv

@@ -0,0 +1,26 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]	0.9885760913912692	2.6753035812734915	0.0074661608491912	0.848706160965601	0.024121442743541	2	P05067	1
+Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]	0.9885760913912692	2.6753035812734915	0.0074661608491912	0.848706160965601	0.024121442743541	2	P05067	1
+Amyloidogenic glycoprotein,  copper-binding domain conserved site [IPR019744]	0.9885760913912692	2.6753035812734915	0.0074661608491912	0.848706160965601	0.024121442743541	2	P05067	1
+Sterol reductase, conserved site [IPR018083]	0.9616483068135456	2.5648678457427954	0.0103215108791778	0.9267983311529204	0.0295570538812821	2	Q9UBM7	1
+Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]	0.8282333741330108	1.9986844474918877	0.0456425068041348	0.9999922875189244	0.0891621063150541	2	P01889	1
+Phosphorylase pyridoxal-phosphate attachment site [IPR035090]	0.7719298245614039	1.7510283358843262	0.0799410292003692	0.9999999992387149	0.1316675775064905	2	P06737	1
+Clathrin adaptor complex, small chain [IPR000804]	0.7535699714402292	1.66937289247492	0.0950435024040485	0.9999999999882462	0.1469384208946026	2	Q92572	1
+Ubiquitin conserved site [IPR019954]	0.7405140758873907	1.6110886264619335	0.1071604069581178	0.9999999999996064	0.161703129062549	2	P54578	1
+Guanylate kinase, conserved site [IPR020590]	0.7372501019991827	1.5964925149998066	0.1103788755717178	0.9999999999998416	0.1655683133575768	2	Q9NZW5	1
+Chromo domain, conserved site [IPR023779]	0.7681632653061208	1.3561700717575036	0.1750450620131087	1.0	0.2433570165916223	3	Q13185,P83916	2
+Proteasome beta-type subunit, conserved site [IPR016050]	0.6356447469755057	1.1863670819913763	0.235477365564606	1.0	0.3074626742087084	8	P49721	1
+HMG box A DNA-binding domain, conserved site [IPR017967]	0.7081632653061198	1.1207378616779338	0.2623994608856168	1.0	0.3373707354243644	3	P09429,P26583	2
+Thioredoxin, conserved site [IPR017937]	0.5638601665157765	1.0771752219801525	0.2814019926378215	1.0	0.3563482519835729	10	Q8IXB1,O95881	2
+Fumarate lyase, conserved site [IPR020557]	0.6128110975112225	1.0386982243072451	0.298945107265685	1.0	0.3766708351547631	2	P07954	1
+Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]	0.6119951040391707	1.035083071896298	0.3006301174293593	1.0	0.3769094009562116	2	P29692	1
+DnaJ domain, conserved site [IPR018253]	0.5810631112701902	0.961265162551797	0.3364188596328481	1.0	0.4155762383699888	8	Q96KC8,Q99543,O60884,P25685,Q8WXX5	5
+Tubulin, conserved site [IPR017975]	0.6472842267532041	0.8953518470013279	0.3705990328579616	1.0	0.4489949821163765	4	Q9BUF5,P68371	2
+Cyclic nucleotide-binding, conserved site [IPR018488]	0.5675234598123262	0.8408496680166104	0.4004321582060826	1.0	0.4782412505589232	2	P10644	1
+Adenylate kinase, conserved site [IPR033690]	0.6237074509132184	0.7967947918201885	0.4255702203707314	1.0	0.5058664883652091	3	P00568	1
+14-3-3 protein, conserved site [IPR023409]	0.599906925792536	0.7512313710685726	0.4525134234476908	1.0	0.5303878265526423	6	P27348	1
+Vinculin, conserved site [IPR000633]	0.5442676458588388	0.7423626724236888	0.4578676291964723	1.0	0.5317172468088065	2	P35221	1
+Ribosomal protein L3, conserved site [IPR019926]	0.4887800897592868	0.5215199899447817	0.6020045838370467	1.0	0.6683046481362809	2	P09001	1
+Zinc finger, RING-type, conserved site [IPR017907]	0.3592205580043279	0.2484838372633038	0.8037600740064978	1.0	0.8439480777068228	10	Q14527	1
+Tr-type G domain, conserved site [IPR031157]	0.3427287581699368	0.0741617223843575	0.9408817030559172	1.0	0.952217627189121	5	Q05639,P15170,P49411,Q96RP9	4
+Clathrin adaptor, mu subunit, conserved site [IPR018240]	0.2975510204081585	0.0406692397107033	0.9675595844528986	1.0	0.971414403514464	3	Q96CW1,Q9Y2T2	2

interpro_conserved_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Aminotransferase, class IV, conserved site [IPR018300]", "Amyloidogenic glycoprotein,  copper-binding domain conserved site [IPR019744]", "Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Bromodomain, conserved site [IPR018359]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific,  conserved site [IPR031303]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "Fibrillarin, conserved site [IPR020813]", "Fork head domain conserved site 2 [IPR030456]", "Fork head domain conserved site1 [IPR018122]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 2, conserved site [IPR023230]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "Homeobox, conserved site [IPR017970]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RIO kinase, conserved site [IPR018935]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P,  conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "Tyrosine-protein kinase, receptor class V, conserved site [IPR001426]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]"], "available_proteins": ["AAAS", "ABCB1", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ACAA2", "ACAD9", "ACADM", "ACADS", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR1B", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA6", "ANXA7", "AP1M1", "AP2M1", "AP3M1", "AP3S1", "APEX1", "APLP2", "APP", "ARIH2", "ATAD1", "ATP5C1", "ATP5O", "BAG6", "BAZ1A", "BAZ1B", "BAZ2A", "BCAT2", "BLM", "BOP1", "BPTF", "BRCA1", "BRD2", "CAD", "CALR", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CBR1", "CBX1", "CBX3", "CBX5", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDKAL1", "CECR2", "CHAF1B", "CHD4", "CLGN", "CMPK1", "CNDP2", "COPA", "COPZ1", "CORO1B", "CORO1C", "CPOX", "CRYZ", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CYP51A1", "DCAF13", "DCAF7", "DCPS", "DCXR", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX6", "DHCR7", "DHFR", "DHRS7", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX38", "DHX40", "DHX8", "DHX9", "DIDO1", "DIMT1", "DIS3", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC2", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DRG1", "DRG2", "DSG2", "DST", "DTYMK", "DYNLL1", "ECH1", "ECHS1", "ECI2", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4E", "ENO1", "EPB41", "EPB41L2", "EPHA7", "EPRS", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FBL", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FOXC1", "FOXK1", "FUCA2", "GAA", "GALK1", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GLA", "GLB1", "GLO1", "GMPPA", "GNPDA1", "GNS", "GPI", "GRHPR", "GRWD1", "GSPT1", "GTF3C2", "GUSB", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HIBADH", "HINT2", "HLA-A", "HLA-B", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMOX1", "HMOX2", "HOXA10", "HSD17B10", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "ILVBL", "IMPDH2", "INA", "IQGAP1", "IVD", "KDM2A", "KDSR", "KIF11", "KIF14", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFC1", "LAMP1", "LARS", "LARS2", "LBR", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRWD1", "LSS", "MACF1", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME1", "ME2", "MGST2", "MID1", "MIF", "MPI", "MPP2", "MPP6", "MPST", "MRPL24", "MRPL3", "MRPS11", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFV1", "NEFL", "NEFM", "NES", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NSD2", "NSF", "NUBP2", "NUDT1", "NUDT12", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL11", "OSBPL6", "OSBPL9", "P4HB", "PAFAH1B1", "PAICS", "PBRM1", "PCNA", "PDIA3", "PDIA4", "PDIA6", "PEBP1", "PEPD", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHGDH", "PHIP", "PI4KB", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PNP", "PNPLA6", "POLD1", "POLR1B", "POLR1C", "POLR2B", "POLR2E", "PPIB", "PPIC", "PPID", "PPIF", "PPIG", "PPIH", "PPIL1", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PUS7", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "RACK1", "RAE1", "RANBP2", "RARS", "RARS2", "RCL1", "RDH13", "RDX", "RECQL5", "RIOK2", "RNF114", "RNF20", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS24", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "RSF1", "RTN4IP1", "S100A10", "S100A11", "SART1", "SBDS", "SCD", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB6", "SERPINH1", "SLC1A5", "SLC27A4", "SLIT2", "SMARCA4", "SMU1", "SNRNP40", "SNU13", "SPATA5", "SPTBN1", "SRCAP", "SRM", "STMN1", "STRN4", "STX12", "STX18", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SYNE2", "TAP1", "TAP2", "TBL3", "TCP1", "THOC6", "TK1", "TLN1", "TMX1", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRIM25", "TRIM28", "TRIM33", "TRIP13", "TSFM", "TSPAN6", "TUBB", "TUBB2B", "TUBB4B", "TUBB6", "TUFM", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UHRF1", "USP10", "USP14", "USP36", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VARS2", "VAT1", "VCL", "VCP", "VIM", "VPS4B", "WARS", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR3", "WDR36", "WDR5", "WDR61", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2"], "leading_proteins": ["AK1", "AP2M1", "AP3M1", "AP3S1", "APP", "CBX1", "CBX3", "CTNNA1", "DHCR7", "DNAJA2", "DNAJB1", "DNAJC1", "DNAJC10", "DNAJC2", "DNAJC9", "EEF1A2", "EEF1D", "FH", "GFM1", "GSPT1", "HLA-B", "HLTF", "HMGB1", "HMGB2", "MPP6", "MRPL3", "PRKAR1A", "PSMB2", "PYGL", "TUBB4B", "TUBB6", "TUFM", "TXNDC12", "USP14", "YWHAQ"]}

interpro_domain/advanced/idx2term.json

@@ -0,0 +1 @@
+{}

interpro_domain/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "K Homology domain [IPR004087]", "1": "Importin-beta, N-terminal domain [IPR001494]", "2": "K Homology domain, type 1 [IPR004088]", "3": "DnaJ domain [IPR001623]", "4": "EF-hand domain [IPR002048]", "5": "PDZ domain [IPR001478]", "6": "Translational (tr)-type GTP-binding domain [IPR000795]", "7": "Translation elongation factor EFTu-like, domain 2 [IPR004161]", "8": "Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) [IPR002314]"}

interpro_domain/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:476eebb9bc2fe951212863b434a1b3ca39be787a91496867159f3fbc7e42dfd2
+size 535145

interpro_domain/df_merge.tsv

@@ -0,0 +1 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_50	pval_100	pval_250	pval_500

interpro_domain/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2453,
+    "annotations_size": 2199,
+    "title": "Average number of proteins per term",
+    "value": 2.049567985447931
+}

interpro_domain/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C334/C334_val_log2fc"}

interpro_domain/result.tsv

@@ -0,0 +1,173 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+MD-2-related lipid-recognition domain [IPR003172]	0.9930640554875564	2.693582346947124	0.007068868125083	0.9999998320571514	0.0204801594295883	2	P61916	1
+Amyloidogenic glycoprotein, heparin-binding [IPR015849]	0.9885760913912692	2.6753035812734915	0.0074661608491912	0.999999930343132	0.0212088416332463	2	P05067	1
+Pancreatic trypsin inhibitor Kunitz domain [IPR002223]	0.9885760913912692	2.6753035812734915	0.0074661608491912	0.999999930343132	0.0212088416332463	2	P05067	1
+Amyloidogenic glycoprotein, E2 domain [IPR024329]	0.9885760913912692	2.6753035812734915	0.0074661608491912	0.999999930343132	0.0212088416332463	2	P05067	1
+Amyloidogenic glycoprotein, copper-binding [IPR011178]	0.9885760913912692	2.6753035812734915	0.0074661608491912	0.999999930343132	0.0212088416332463	2	P05067	1
+Beta-amyloid precursor protein C-terminal [IPR019543]	0.9885760913912692	2.6753035812734915	0.0074661608491912	0.999999930343132	0.0212088416332463	2	P05067	1
+Amyloidogenic glycoprotein, extracellular [IPR008154]	0.9885760913912692	2.6753035812734915	0.0074661608491912	0.999999930343132	0.0212088416332463	2	P05067	1
+Beta-hexosaminidase, eukaryotic type, N-terminal [IPR029019]	0.9832721338229296	2.653654598125777	0.0079625286113813	0.999999976813208	0.0221360308677972	2	P06865	1
+Glycoside hydrolase family 20, catalytic domain [IPR015883]	0.9832721338229296	2.653654598125777	0.0079625286113813	0.999999976813208	0.0221360308677972	2	P06865	1
+Immunoglobulin V-set domain [IPR013106]	0.9441044471644237	2.4922127837904045	0.012694995834515	0.9999999999993712	0.0318427643870297	2	Q9Y624	1
+N-acetylgalactosaminyltransferase [IPR045885]	0.9273765809873532	2.422420260872322	0.0154175089334804	0.9999999999999986	0.0369168569978109	2	Q10472	1
+NECAP, PHear domain [IPR012466]	0.8788249694002475	2.2170255462201496	0.0266213458841453	1.0	0.0562347162336556	2	Q8NC96	1
+CRIB domain [IPR000095]	0.840065279477764	2.0501260398653645	0.0403521329213796	1.0	0.0783872264082277	2	Q13177	1
+p21 activated kinase binding domain [IPR033923]	0.840065279477764	2.0501260398653645	0.0403521329213796	1.0	0.0783872264082277	2	Q13177	1
+Prolyl 4-hydroxylase alpha-subunit, N-terminal [IPR013547]	0.8392492860057148	2.0465855495462457	0.040698794868879	1.0	0.0787969352406523	2	O15460	1
+Extended PHD (ePHD) domain [IPR034732]	0.8359853121175067	2.0324128454753283	0.0421118787536332	1.0	0.0807167410388493	2	Q03164	1
+Immunoglobulin-like domain [IPR007110]	0.7712142573189515	1.9322097077245015	0.0533336274731239	1.0	0.0970061443226639	9	P10321,Q92692,Q9Y624,P35613	4
+EB1, C-terminal [IPR004953]	0.7992656058751539	1.8718288634275304	0.061230283699428	1.0	0.1081489107269416	2	Q15555	1
+Marvel domain [IPR008253]	0.7988576091391328	1.8700333290717568	0.0614791897075144	1.0	0.1084143850575976	2	O43760	1
+Translation initiation factor IF2/IF5 domain [IPR002735]	0.7968176254590006	1.8610521262452229	0.062736815896746	1.0	0.1101538190597238	2	P55010	1
+Nucleotidyl transferase domain [IPR005835]	0.7894736842105292	1.8286717930781693	0.0674487904836589	1.0	0.116751198599032	2	Q9NR50	1
+Ricin B, lectin domain [IPR000772]	0.8781373915728726	1.7853706244291705	0.0742012202018349	1.0	0.1254177426778132	3	Q10472	1
+Histone deacetylase domain [IPR023801]	0.7768257853937219	1.7727359328011207	0.0762724739474052	1.0	0.128130764102631	2	Q13547	1
+CTP synthase GATase domain [IPR033828]	0.7690738474092269	1.738351998523162	0.0821488092275206	1.0	0.135416215510733	2	Q9NRF8	1
+CTP synthase, N-terminal [IPR017456]	0.7690738474092269	1.738351998523162	0.0821488092275206	1.0	0.135416215510733	2	Q9NRF8	1
+HR1 rho-binding domain [IPR011072]	0.7613219094247227	1.703896231921929	0.0884004751073499	1.0	0.1414793629993176	2	O75116	1
+Sterile alpha motif domain [IPR001660]	0.8525146093821727	1.6827709157853008	0.0924194473622765	1.0	0.1467367254510081	4	Q15375	1
+Plasma membrane calcium transporting P-type ATPase, C-terminal [IPR022141]	0.7552019583843375	1.6766463556083295	0.0936116563632827	1.0	0.1481769388628863	2	P20020	1
+K Homology domain [IPR004087]	0.5732013673042776	1.6269354376676126	0.1037508105646387	1.0	0.1604416543119835	22	O75179,Q06787,Q8IWZ3,Q9NRX1,Q96PU8	5
+L27 domain [IPR004172]	0.7372501019991827	1.5964925149998066	0.1103788755717178	1.0	0.1689573337469563	2	Q9NZW5	1
+L27 domain, C-terminal [IPR014775]	0.7372501019991827	1.5964925149998066	0.1103788755717178	1.0	0.1689573337469563	2	Q9NZW5	1
+MHC class I, alpha chain, C-terminal [IPR010579]	0.8285714285714267	1.592957716481764	0.1111696770287329	1.0	0.1691004127632818	3	P10321,P01889	2
+MHC class I-like antigen recognition-like [IPR011161]	0.8285714285714267	1.592957716481764	0.1111696770287329	1.0	0.1691004127632818	3	P10321,P01889	2
+MHC class I alpha chain, alpha1 alpha2 domains [IPR001039]	0.8285714285714267	1.592957716481764	0.1111696770287329	1.0	0.1691004127632818	3	P10321,P01889	2
+Immunoglobulin C1-set [IPR003597]	0.8285714285714267	1.592957716481764	0.1111696770287329	1.0	0.1691004127632818	3	P10321,P01889	2
+CAP Gly-rich domain [IPR000938]	0.7364341085271374	1.5928420332034747	0.1111956329493886	1.0	0.1691004127632818	2	Q14203	1
+Importin-beta, N-terminal domain [IPR001494]	0.6520066411756222	1.5519005344201349	0.1206860250339256	1.0	0.180139624240487	12	Q8TEX9,P55060,O00410,Q9UI26,O95373	5
+ERAP1-like C-terminal domain [IPR024571]	0.8145608058963384	1.5375923161687246	0.1241483273877324	1.0	0.183469201562919	4	Q9UIQ6	1
+CARG-binding factor, N-terminal [IPR012956]	0.7176662586699292	1.508738437532887	0.1313656386214399	1.0	0.1925820262190309	2	Q99729	1
+Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862]	0.8036734693877534	1.4955716688579106	0.1347653106068309	1.0	0.1959910418996831	3	P13674,O15460	2
+PTB/PI domain [IPR006020]	0.71154630762954	1.481263334518242	0.1385364148966537	1.0	0.1996340605227663	2	O60343	1
+Translation initiation factor IF- 2, domain 3 [IPR023115]	0.7070583435332558	1.4611027774659884	0.1439872381238318	1.0	0.2053358862738691	2	P46199	1
+K Homology domain, type 1 [IPR004088]	0.5491983544206951	1.4523186505679708	0.1464130239735108	1.0	0.2078516718642675	21	O75179,Q06787,Q8IWZ3,P51114,Q92667,Q96PU8	6
+Fragile X-related 1 protein, C-terminal region 1 [IPR032172]	0.7029783761729971	1.442767468539699	0.1490859861202378	1.0	0.2101538996656429	2	P51114	1
+Immunoglobulin subtype [IPR003599]	0.7831682737407094	1.4316693704502494	0.152238466211483	1.0	0.2135976299706964	6	Q9Y624,P35613	2
+Zinc finger, CXXC-type [IPR002857]	0.7848960384343056	1.4219074240013807	0.1550531277133973	1.0	0.2158408392276924	3	Q9Y2K7	1
+Peptidase M20, dimerisation domain [IPR011650]	0.6972664218686242	1.4170882628559722	0.1564571236935608	1.0	0.2176056776119685	2	Q96KP4	1
+Ubiquitin-associated domain [IPR015940]	0.6414702265839048	1.3823076273044914	0.1668772650386731	1.0	0.2266053220170286	9	Q13501,Q9Y5A7,Q7Z6Z7	3
+Ancestral coatomer element 1, Sec16/Sec31 [IPR024298]	0.6895144838841326	1.3822251798684702	0.1669025709848157	1.0	0.2266053220170286	2	O94979	1
+Chromo shadow domain [IPR008251]	0.7681632653061208	1.3561700717575036	0.1750450620131087	1.0	0.2340061177226351	3	Q13185,P83916	2
+Chromo domain subgroup [IPR017984]	0.7681632653061208	1.3561700717575036	0.1750450620131087	1.0	0.2340061177226351	3	Q13185,P83916	2
+Aminopeptidase N-like , N-terminal domain [IPR045357]	0.7622076817904524	1.353212158742935	0.1759878620205497	1.0	0.2348284639461097	6	Q9UIQ6	1
+Peptidase M1, membrane alanine aminopeptidase [IPR014782]	0.7622076817904524	1.353212158742935	0.1759878620205497	1.0	0.2348284639461097	6	Q9UIQ6	1
+DnaJ domain [IPR001623]	0.5892283177580224	1.346776535229231	0.1780522141300569	1.0	0.2371513136717111	14	Q99615,Q96KC8,Q8IXB1,Q99543,O60884,Q13217,P25685,Q8WXX5	8
+Exportin-2, central domain [IPR013713]	0.7575510204081612	1.3144598117164443	0.1886915138409608	1.0	0.2458131747252801	3	O95373,P55060	2
+Serine-threonine/tyrosine-protein kinase, catalytic domain [IPR001245]	0.7453494564234897	1.2899885949931245	0.197054617998267	1.0	0.2536260203546486	6	Q15375	1
+Immunoglobulin subtype 2 [IPR003598]	0.7410996202094624	1.2815908824686282	0.1999862002385013	1.0	0.2562760223336039	5	Q9Y624	1
+Peptidase C2, calpain, catalytic domain [IPR001300]	0.6658506731946174	1.2758021665712502	0.202025461510567	1.0	0.2576879291541397	2	P17655	1
+Peptidase C2, calpain, large subunit, domain III [IPR022682]	0.6658506731946174	1.2758021665712502	0.202025461510567	1.0	0.2576879291541397	2	P17655	1
+Peptidase C2, calpain, domain III [IPR022683]	0.6658506731946174	1.2758021665712502	0.202025461510567	1.0	0.2576879291541397	2	P17655	1
+Calpain subdomain III [IPR033883]	0.6658506731946174	1.2758021665712502	0.202025461510567	1.0	0.2576879291541397	2	P17655	1
+Ubiquitin-conjugating enzyme E2 [IPR000608]	0.656155554685532	1.2711692742368992	0.2036684348804187	1.0	0.259182227026644	8	P49427	1
+BTB/POZ domain [IPR000210]	0.7365344281790506	1.2641301018523523	0.2061833338682568	1.0	0.2619278747407838	5	Q08380	1
+ZU5 domain [IPR000906]	0.6621787025703805	1.259301323136777	0.2079215155122877	1.0	0.2639834945794	2	Q07157	1
+Dynamin-type guanine nucleotide-binding (G) domain [IPR030381]	0.7365791464088192	1.2570739704243368	0.2087268516280778	1.0	0.2647003152999672	6	Q8IWA4,Q9H4M9	2
+Dynamin, N-terminal [IPR045063]	0.7365791464088192	1.2570739704243368	0.2087268516280778	1.0	0.2647003152999672	6	Q8IWA4,Q9H4M9	2
+SET domain [IPR001214]	0.7414884660915582	1.2513445578518736	0.2108087954760298	1.0	0.2670325698455009	3	Q9H7B4	1
+Guanylate kinase/L-type calcium channel beta subunit [IPR008145]	0.7378521845651296	1.2417744989291148	0.2143197740501579	1.0	0.2711675392038534	4	Q07157,Q9NZW5,Q9UDY2	3
+Guanylate kinase-like domain [IPR008144]	0.7378521845651296	1.2417744989291148	0.2143197740501579	1.0	0.2711675392038534	4	Q07157,Q9NZW5,Q9UDY2	3
+Fragile X-related 1 protein, C-terminal core [IPR022034]	0.7262478546829623	1.1915312471215571	0.2334450973860358	1.0	0.2928384307768926	3	Q06787	1
+Agenet-like domain [IPR008395]	0.7262478546829623	1.1915312471215571	0.2334450973860358	1.0	0.2928384307768926	3	Q06787	1
+Synaptic functional regulator FMRP, KH0 domain [IPR040472]	0.7262478546829623	1.1915312471215571	0.2334450973860358	1.0	0.2928384307768926	3	Q06787	1
+Fxr1, tudor domain [IPR041560]	0.7262478546829623	1.1915312471215571	0.2334450973860358	1.0	0.2928384307768926	3	Q06787	1
+AP complex, mu/sigma subunit [IPR022775]	0.7068361949470747	1.1506131637681705	0.2498914149918216	1.0	0.3125774866706574	5	Q92572,Q96CW1,P48444	3
+26S proteasome regulatory subunit Rpn7, N-terminal [IPR045135]	0.6372909016727886	1.1477116868403554	0.2510876050001416	1.0	0.3138951923793697	2	Q13098	1
+FAD/NAD(P)-binding domain [IPR023753]	0.7033027255521554	1.1086125606403148	0.2675973571752468	1.0	0.3330201405933037	4	O95831	1
+BRO1 domain [IPR004328]	0.6283149734802145	1.1076283156787967	0.2680223694348038	1.0	0.3333604018026774	2	Q5VW32	1
+Glycosyltransferase 2-like [IPR001173]	0.6947557782980485	1.068448204448836	0.2853183826620724	1.0	0.3538720380563436	3	Q10472	1
+Myosin tail [IPR002928]	0.692610147517002	1.0600998173807	0.289099190884388	1.0	0.3579555860105683	3	P35579	1
+Cytochrome b5-like heme/steroid binding domain [IPR001199]	0.6400098054735706	1.0444816946986426	0.2962625840229429	1.0	0.3647712330719213	7	Q8WUJ1	1
+Fumarate lyase, N-terminal [IPR022761]	0.6128110975112225	1.0386982243072451	0.298945107265685	1.0	0.3676623550767569	2	P07954	1
+Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain [IPR014038]	0.6119951040391707	1.035083071896298	0.3006301174293593	1.0	0.3693215800151738	2	P29692	1
+Elongation factor 1 beta central acidic region, eukaryote [IPR018940]	0.6119951040391707	1.035083071896298	0.3006301174293593	1.0	0.3693215800151738	2	P29692	1
+FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]	0.5485843872358458	0.9788585767252046	0.3276498619683439	1.0	0.3987827145693531	9	O00170,Q9NWM8	2
+SNF2, N-terminal [IPR000330]	0.541449038276413	0.948014674591644	0.3431219836609385	1.0	0.4166345897683068	9	Q2NKX8,Q9H4L7,Q14527	3
+Zinc finger, LIM-type [IPR001781]	0.5713146092126131	0.9213706401207872	0.3568569518853417	1.0	0.4302239239012426	8	Q16527,Q9UHB6	2
+EF-hand domain [IPR002048]	0.4193606024648769	0.9124786421232484	0.361516807645311	1.0	0.4351261412216962	37	Q02818,Q9Y680,P80303,Q9BRK5,Q9NWM8,Q14257,O43852	7
+Plectin/S10, N-terminal [IPR005326]	0.5826193390452918	0.9060636969847676	0.3649021389177556	1.0	0.4382412908138419	2	P46783	1
+Septin-type guanine nucleotide-binding (G) domain [IPR030379]	0.651020408163262	0.8998042487799076	0.3682244328944235	1.0	0.4415079214475667	3	Q16181,Q15019	2
+Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]	0.6472842267532041	0.8953518470013279	0.3705990328579616	1.0	0.4438710638641925	4	Q9BUF5,P68371	2
+Tubulin/FtsZ, GTPase domain [IPR003008]	0.6472842267532041	0.8953518470013279	0.3705990328579616	1.0	0.4438710638641925	4	Q9BUF5,P68371	2
+RING-type zinc-finger, LisH dimerisation motif [IPR027370]	0.6472977915594131	0.8856370580197453	0.3758131355460381	1.0	0.4496262704383775	3	Q9Y508	1
+P-type ATPase, haloacid dehalogenase domain [IPR044492]	0.6338890394308648	0.8748449833693627	0.3816582575236689	1.0	0.4553806339091415	5	P20020,Q9HD20	2
+EF-hand, Ca insensitive [IPR014837]	0.6412971774683411	0.8628790116039672	0.3882039914942501	1.0	0.4621876433653795	3	O43707	1
+cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain [IPR003117]	0.5675234598123262	0.8408496680166104	0.4004321582060826	1.0	0.4752025450054914	2	P10644	1
+PWI domain [IPR002483]	0.621291969745555	0.8281602742007513	0.4075797382852819	1.0	0.4818644325211478	5	Q9P2N5,Q5T8P6,O43395	3
+Thioredoxin domain [IPR013766]	0.4404424201400136	0.8226096817750546	0.4107299911454074	1.0	0.4853279153835308	21	Q8IXB1,O95881,Q6ZRP7,O14530	4
+CS domain [IPR007052]	0.5465573143147497	0.8208819243956244	0.4117135279494284	1.0	0.4862288120090188	8	Q15185,Q8WVJ2,Q96RS6	3
+PurM-like, C-terminal domain [IPR010918]	0.6233222713705466	0.7953591885191128	0.4264045927390221	1.0	0.5011564401032119	3	P49903	1
+Tudor domain [IPR002999]	0.5686032901984962	0.7685397297738854	0.4421665965303258	1.0	0.5174690504365016	7	Q92667,Q14739	2
+Threonyl/alanyl tRNA synthetase, SAD [IPR012947]	0.601263191364671	0.7548541821349408	0.4503364796596882	1.0	0.5261901800061927	5	Q9BW92	1
+14-3-3 domain [IPR023410]	0.599906925792536	0.7512313710685726	0.4525134234476908	1.0	0.5284530101760341	6	P27348	1
+Chromo domain [IPR023780]	0.6063308504794236	0.7438477424853642	0.456968593121787	1.0	0.5330896213659468	4	Q13185,P83916	2
+Endonuclease/exonuclease/phosphatase [IPR005135]	0.6046428436030928	0.7377228130516789	0.4606829062272013	1.0	0.536853052884799	4	Q9ULM6	1
+tRNA-binding domain [IPR002547]	0.5373317013463953	0.7135491400957221	0.4755060166918408	1.0	0.5526626483643541	2	Q12904	1
+Ran binding domain [IPR000156]	0.5928084681487696	0.6951062619995125	0.486988710724535	1.0	0.5651124933420857	4	P43487	1
+Target SNARE coiled-coil homology domain [IPR000727]	0.5874558533233909	0.6760302239601628	0.4990214558992214	1.0	0.5775516744854673	4	Q86Y82	1
+Glutaredoxin, PICOT-like [IPR033658]	0.522235822113424	0.6518932728205554	0.5144700249499663	1.0	0.5929347929061719	2	Q86SX6	1
+TOG domain [IPR034085]	0.5325322677602449	0.6345247207660423	0.525738438934056	1.0	0.6040223757659297	7	Q8TEX9,O75122,Q7Z460,O00410	4
+PDZ domain [IPR001478]	0.442637615710224	0.6130989630753804	0.5398109058120797	1.0	0.6185743522046708	13	Q6ZWJ1,Q07157,Q9NZW5,Q9UDY2,Q96HC4,O43464	6
+GOLD domain [IPR009038]	0.5682442685134996	0.6087158408059344	0.542712805351276	1.0	0.6215757598788832	4	Q9BVK6,Q9H3P7	2
+Ribosomal protein S7 domain [IPR023798]	0.4985720114239117	0.5586668312686626	0.5763891201219409	1.0	0.6550282558905157	2	P46782	1
+Helicase/UvrB, N-terminal [IPR006935]	0.496940024479811	0.5524130162884487	0.5806654147418342	1.0	0.6595471317238086	2	P19447	1
+Translational (tr)-type GTP-binding domain [IPR000795]	0.4357781007219316	0.5449431371272776	0.5857926266761453	1.0	0.6639989618870328	11	Q05639,O00178,P46199,O60841,Q7Z2Z2,P49411	6
+OBG-type guanine nucleotide-binding (G) domain [IPR031167]	0.5322211742547527	0.5150536356561868	0.6065155404183322	1.0	0.6818648636911618	5	P55039,A4D1E9	2
+TGS [IPR004095]	0.5280237776655407	0.5051640478422367	0.6134436194938293	1.0	0.6885975085589233	6	Q9BW92,P55039	2
+Cation-transporting P-type ATPase, C-terminal [IPR006068]	0.5308697480809376	0.484023299488093	0.6283693336739853	1.0	0.7039145006363188	4	P20020	1
+Cation-transporting P-type ATPase, N-terminal [IPR004014]	0.5308697480809376	0.484023299488093	0.6283693336739853	1.0	0.7039145006363188	4	P20020	1
+Ribosomal L28e/Mak16 [IPR029004]	0.4769481844145331	0.4779099800759948	0.6327142777904389	1.0	0.7069810451530362	2	P46779	1
+Translation elongation factor EFTu/EF1A, C-terminal [IPR004160]	0.523009702228974	0.4590569424039475	0.6461932756754143	1.0	0.7202123736493846	4	Q05639,P49411	2
+THIF-type NAD/FAD binding fold [IPR000594]	0.5071268664843234	0.4350045223410287	0.6635591448736249	1.0	0.7338764383653403	5	Q8TBC4	1
+B-box, C-terminal [IPR003649]	0.5175510204081585	0.430377536132148	0.6669210334362379	1.0	0.7369644987569283	3	Q13263,Q9UPN9	2
+Serine-tRNA ligase catalytic core domain [IPR033729]	0.461036311709507	0.4216990392003851	0.6732447058444033	1.0	0.7434334551080896	2	Q9NP81	1
+Alanyl-tRNA synthetase, class IIc, N-terminal [IPR018164]	0.4606283149734817	0.420297181290826	0.6742683687827462	1.0	0.7434334551080896	2	Q5JTZ9	1
+Death domain [IPR000488]	0.5121798214467764	0.4139818246669011	0.6788874176866697	1.0	0.7464367157464933	3	Q13546	1
+Chaperone DnaJ, C-terminal [IPR002939]	0.5057341256468096	0.4059744990255836	0.684761337644068	1.0	0.750643161255885	4	O60884,P25685	2
+Arf GTPase activating protein [IPR001164]	0.455732354141166	0.40363663408966	0.6864799424045962	1.0	0.7521521640995052	2	Q8N6T3	1
+Zinc finger, RanBP2-type [IPR001876]	0.3969663249212936	0.3664837289251629	0.7140041518043803	1.0	0.7765059989207875	9	P35637,Q92804	2
+Survival motor neuron [IPR010304]	0.4345165238678111	0.3350981721278865	0.7375510316628928	1.0	0.7965985847871814	2	Q16637	1
+SAB domain [IPR007477]	0.4320685434516521	0.3275950077039094	0.7432178971039007	1.0	0.7999687497461957	2	P11171	1
+Band 4.1, C-terminal [IPR008379]	0.4320685434516521	0.3275950077039094	0.7432178971039007	1.0	0.7999687497461957	2	P11171	1
+FERM adjacent (FA) [IPR014847]	0.4320685434516521	0.3275950077039094	0.7432178971039007	1.0	0.7999687497461957	2	P11171	1
+PPM-type phosphatase domain [IPR001932]	0.431660546715627	0.3263530009694156	0.7441572923142696	1.0	0.8005880067510172	2	Q9H0C8	1
+DALR anticodon binding [IPR008909]	0.4275805793553642	0.3140684388343496	0.7534690597378884	1.0	0.808517918856774	2	Q5T160	1
+Arginyl-tRNA synthetase, catalytic core domain [IPR035684]	0.4275805793553642	0.3140684388343496	0.7534690597378884	1.0	0.808517918856774	2	Q5T160	1
+WHEP-TRS domain [IPR000738]	0.4630461412821558	0.2870286914442487	0.7740903515276956	1.0	0.8259217287770028	4	P07814,P41250,P23381	3
+Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal [IPR015211]	0.4145246838025315	0.2764610776086914	0.7821939506516264	1.0	0.8320516634552689	2	P09960	1
+Oxoglutarate/iron-dependent dioxygenase [IPR005123]	0.4156751780861533	0.2583165921038716	0.796162582055751	1.0	0.8443036949027674	7	O60568,P13674,O15460	3
+Prolyl 4-hydroxylase, alpha subunit [IPR006620]	0.4156751780861533	0.2583165921038716	0.796162582055751	1.0	0.8443036949027674	7	O60568,P13674,O15460	3
+Mu homology domain [IPR028565]	0.4495343346819461	0.253517007836491	0.7998687200010806	1.0	0.846128736337411	4	P48444	1
+UBX domain [IPR001012]	0.4374685123427118	0.2178699587861861	0.827530434305634	1.0	0.8706887201139182	3	Q96CS3	1
+Glutamine amidotransferase type 2 domain [IPR017932]	0.4310204081632593	0.204115705475103	0.838263081503783	1.0	0.8802963305763223	3	P08243,Q06210	2
+Hotdog acyl-CoA thioesterase (ACOT)-type domain [IPR033120]	0.3827009383924898	0.1963932395276021	0.8443023873037219	1.0	0.8849480217735388	2	O00154	1
+Aminotransferase, class I/classII [IPR004839]	0.4126226213339603	0.1871368820652458	0.8515533112240916	1.0	0.8897731757265737	5	O15269	1
+CLASP N-terminal domain [IPR024395]	0.4187755102040755	0.1795187538377101	0.857530393087448	1.0	0.8937011063503784	3	O75122,Q7Z460	2
+Valyl tRNA synthetase, anticodon-binding domain [IPR033705]	0.3663810689514462	0.1620710881954683	0.8712498734387328	1.0	0.9061232054856384	2	Q5ST30	1
+OCRE domain [IPR041591]	0.3639330885352908	0.157325819449579	0.874988072657388	1.0	0.9080220725689458	2	P98175	1
+Importin-alpha, importin-beta-binding domain [IPR002652]	0.401388321763988	0.1525888666672217	0.8787225052914058	1.0	0.9101387150089044	4	P52294,O00629,P52292	3
+Translation elongation factor EFTu-like, domain 2 [IPR004161]	0.3431492842535705	0.1412854632894057	0.8876444330324293	1.0	0.917266831613327	8	Q05639,Q9Y450,Q15029,O60841,P15170,P49411,Q96RP9	7
+DNA mismatch repair protein MutS-like, N-terminal [IPR007695]	0.3963265306122401	0.1396936362429354	0.8889020546466575	1.0	0.917266831613327	3	P52701,P20585	2
+DNA mismatch repair protein MutS, C-terminal [IPR000432]	0.3963265306122401	0.1396936362429354	0.8889020546466575	1.0	0.917266831613327	3	P52701,P20585	2
+DNA mismatch repair protein MutS, core [IPR007696]	0.3963265306122401	0.1396936362429354	0.8889020546466575	1.0	0.917266831613327	3	P52701,P20585	2
+DNA mismatch repair protein MutS, connector domain [IPR007860]	0.3963265306122401	0.1396936362429354	0.8889020546466575	1.0	0.917266831613327	3	P52701,P20585	2
+RuvB-like, AAA-lid domain [IPR041048]	0.348837209302327	0.1303831672776691	0.8962632834708288	1.0	0.9226980151462324	2	Q9Y230	1
+TIP49, P-loop domain [IPR010339]	0.348837209302327	0.1303831672776691	0.8962632834708288	1.0	0.9226980151462324	2	Q9Y230	1
+Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) [IPR002314]	0.3759705762157833	0.120369817184963	0.9041901999279008	1.0	0.92955317888801	6	P41250,P49591,Q9BW92,P07814,Q9NP81	5
+Glutamine amidotransferase [IPR017926]	0.3791762561826611	0.1163061733204406	0.9074098932165768	1.0	0.9315566550808836	4	Q9NRF8	1
+AARP2CN [IPR012948]	0.3243574051407527	0.0949920141759833	0.9243211700019444	1.0	0.9449475838374132	2	Q2NL82	1
+Ribosome biogenesis protein BMS1/TSR1, C-terminal [IPR007034]	0.3243574051407527	0.0949920141759833	0.9243211700019444	1.0	0.9449475838374132	2	Q2NL82	1
+Bms1/Tsr1-type G domain [IPR030387]	0.3243574051407527	0.0949920141759833	0.9243211700019444	1.0	0.9449475838374132	2	Q2NL82	1
+G-patch domain [IPR000467]	0.3148798147279145	0.0862583792212994	0.931261023679974	1.0	0.9498344114435358	8	Q8N1G2,Q5T3I0	2
+LEM domain [IPR003887]	0.3521255113482222	0.0856176263036397	0.9317703861469366	1.0	0.9499133422054304	5	Q9Y2U8	1
+WW domain [IPR001202]	0.296891560350471	0.0842457272603345	0.9328610622888835	1.0	0.9505845579116102	10	Q6ZWJ1,O60828,Q8N1G2	3
+Peptidase M24 [IPR000994]	0.3488562091503286	0.0815041853445041	0.935040996531197	1.0	0.9523645907235304	5	P12955,P50579,Q9NQW7,Q9Y5B9	4
+Zinc finger, RING-type [IPR001841]	0.2953572357001605	0.0773908942551041	0.938312584390075	1.0	0.955254339386007	18	Q12899,Q14527	2
+Histidine kinase/HSP90-like ATPase [IPR003594]	0.3258313273861565	0.0740534485585268	0.9409678561711144	1.0	0.9570713763738578	7	Q02880	1
+Zinc finger, UBR-type [IPR003126]	0.3408163265306079	0.0700319066952302	0.9441682641032244	1.0	0.9598825764045265	3	Q8N806,Q5T4S7	2
+Thioesterase domain [IPR006683]	0.2962056303549502	0.0660271981885322	0.9473561716742565	1.0	0.9611663712097004	2	O00154	1
+NAD-dependent epimerase/dehydratase [IPR001509]	0.326530612244893	0.0582206368115545	0.9535728828037175	1.0	0.9658713815225126	3	Q13630,Q9NRG7	2
+GTP binding domain [IPR006073]	0.2726855466941734	0.0330703866300398	0.9736184578734012	1.0	0.9848146222923684	11	P55039,P36915,A4D1E9	3
+Phosphoribosyltransferase domain [IPR000836]	0.2691993464052309	0.0191046556726116	0.9847576174191291	1.0	0.9947092332129835	5	Q06203,P07741,P00492,O60256	4
+BRCT domain [IPR001357]	0.2507685372183964	0.0180967822711993	0.985561644907876	1.0	0.9950643053959686	9	P38398	1

interpro_family/advanced/idx2term.json

@@ -0,0 +1 @@
+{}

interpro_family/basic/idx2term.json

@@ -0,0 +1 @@
+{}

interpro_family/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:da07f342ef21767832a6f7140a8bc67b5c94b62f93e16f95afc7b12e73acd729
+size 575200

interpro_family/df_merge.tsv

@@ -0,0 +1 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_50	pval_100	pval_250	pval_500

interpro_family/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2453,
+    "annotations_size": 1958,
+    "title": "Average number of proteins per term",
+    "value": 1.2579162410623084
+}

interpro_family/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_family/fragment/C334/C334_val_log2fc"}

interpro_family/result.tsv

@@ -0,0 +1,80 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Amyloidogenic glycoprotein [IPR008155]	0.9885760913912692	2.6753035812734915	0.0074661608491912	0.9999995760240264	0.0168031528077201	2	P05067	1
+CD36 family [IPR002159]	0.9857201142390862	2.6636527400298737	0.0077297311521298	0.999999747943055	0.0171986518134888	2	Q14108	1
+Beta-hexosaminidase [IPR025705]	0.9832721338229296	2.653654598125777	0.0079625286113813	0.9999998407885932	0.0175966490079962	2	P06865	1
+Mitochondrial inner membrane translocase complex, subunit Tim17 [IPR005678]	0.9714402284781728	2.605177786860294	0.0091826597919495	0.9999999856957228	0.0195218760832108	2	O60830	1
+Ergosterol biosynthesis ERG4/ERG24 [IPR001171]	0.9616483068135456	2.5648678457427954	0.0103215108791778	0.9999999984950978	0.0212508078879393	2	Q9UBM7	1
+V-type  ATPase, V0 complex, 116kDa subunit family [IPR002490]	0.9298245614035092	2.4326652332576995	0.0149881511710612	0.999999999999856	0.028492038828095	2	Q93050	1
+ATPase, V0 complex, subunit 116kDa, eukaryotic [IPR026028]	0.9298245614035092	2.4326652332576995	0.0149881511710612	0.999999999999856	0.028492038828095	2	Q93050	1
+Nucleobindin [IPR040250]	0.9171766625867016	2.379617250469402	0.017330628570765	0.9999999999999988	0.0318324303391725	2	Q02818	1
+Sodium/potassium-transporting ATPase subunit beta [IPR000402]	0.8755609955120367	2.203069076606237	0.0275898803448271	1.0	0.0461651361147496	2	P05026	1
+Peptidase S10, serine carboxypeptidase [IPR001563]	0.9832653061224488	2.1844510853271144	0.0289291178825092	1.0	0.0479620768958113	3	Q9HB40,Q9H3G5	2
+Prolyl 4-hydroxylase [IPR045054]	0.8392492860057148	2.0465855495462457	0.040698794868879	1.0	0.0628952173269654	2	O15460	1
+Nucleosome assembly protein (NAP) [IPR002164]	0.9306122448979588	1.9862834701665395	0.0470018570168875	1.0	0.0707920277223582	3	P55209,Q01105	2
+Flotillin family [IPR027705]	0.8159934720522235	1.945237622652008	0.0517463856800453	1.0	0.0764055096929318	2	O75955	1
+RNA-binding protein 26/27 [IPR045137]	0.810281517747862	1.9202175950962943	0.0548304200323581	1.0	0.0800581375267392	2	Q9P2N5	1
+Transmembrane protein GPR107/GPR108-like [IPR009637]	0.8017135862913158	1.882597090600185	0.0597549909701529	1.0	0.0856517366907462	2	Q5VW38	1
+Microtubule-associated protein RP/EB [IPR027328]	0.7992656058751539	1.8718288634275304	0.061230283699428	1.0	0.0872553824479477	2	Q15555	1
+Translation initiation factor IF2/IF5 [IPR045196]	0.7968176254590006	1.8610521262452229	0.062736815896746	1.0	0.0889262635765339	2	P55010	1
+Peptidyl-tRNA hydrolase, PTH2 [IPR002833]	0.7927376580987358	1.843072238905229	0.0653184639598656	1.0	0.0914832277778375	2	Q9Y3E5	1
+TAF15/EWS/TLS family [IPR034870]	0.892244897959183	1.839694122537653	0.0658131569362514	1.0	0.0920440896010813	3	P35637,Q92804	2
+Histone deacetylase family [IPR000286]	0.7768257853937219	1.7727359328011207	0.0762724739474052	1.0	0.1031363977824719	2	Q13547	1
+Histone deacetylase [IPR003084]	0.7768257853937219	1.7727359328011207	0.0762724739474052	1.0	0.1031363977824719	2	Q13547	1
+Glycosyl transferase, family 35 [IPR000811]	0.7719298245614039	1.7510283358843262	0.0799410292003692	1.0	0.1067698057123622	2	P06737	1
+Glycogen/starch/alpha-glucan phosphorylase [IPR011833]	0.7719298245614039	1.7510283358843262	0.0799410292003692	1.0	0.1067698057123622	2	P06737	1
+CTP synthase [IPR004468]	0.7690738474092269	1.738351998523162	0.0821488092275206	1.0	0.1091971272691686	2	Q9NRF8	1
+P-type ATPase, subfamily IIB [IPR006408]	0.7552019583843375	1.6766463556083295	0.0936116563632827	1.0	0.1209845697421172	2	P20020	1
+Tight junction protein ZO [IPR005417]	0.7384740922072672	1.601967157585206	0.1091628722075119	1.0	0.1358810577128471	2	Q9UDY2	1
+Snf7 family [IPR005024]	0.731538147694826	1.570927448188845	0.1161995020840787	1.0	0.1426449060066621	2	Q9Y3E7	1
+Aminopeptidase N-type [IPR034016]	0.8145608058963384	1.5375923161687246	0.1241483273877324	1.0	0.1492218692603929	4	Q9UIQ6	1
+SCAMP [IPR007273]	0.7996931752909955	1.479969748419069	0.1388813201051872	1.0	0.1628321106382974	3	O15127	1
+Translation initiation factor IF- 2 [IPR015760]	0.7070583435332558	1.4611027774659884	0.1439872381238318	1.0	0.1681139011606814	2	P46199	1
+Peptidase M20 [IPR002933]	0.6972664218686242	1.4170882628559722	0.1564571236935608	1.0	0.1803078564991124	2	Q96KP4	1
+Small GTPase superfamily, ARF type [IPR024156]	0.686658506731952	1.3693787524771852	0.170880912430376	1.0	0.1934016338373851	2	P40616	1
+Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase [IPR001930]	0.7622076817904524	1.353212158742935	0.1759878620205497	1.0	0.198036915997837	6	Q9UIQ6	1
+Peptidase C2, calpain family [IPR022684]	0.6658506731946174	1.2758021665712502	0.202025461510567	1.0	0.2203709491017772	2	P17655	1
+Proteasome B-type subunit [IPR023333]	0.6854238085256057	1.2230245958434698	0.2213204065925895	1.0	0.2400805296998838	7	P49721	1
+Fragile X mental retardation syndrome-related protein [IPR040148]	0.7262478546829623	1.1915312471215571	0.2334450973860358	1.0	0.2525334257910818	3	Q06787	1
+26S proteasome regulatory subunit Rpn7/COP9 signalosome complex subunit 1 [IPR019585]	0.6372909016727886	1.1477116868403554	0.2510876050001416	1.0	0.2713609013181706	2	Q13098	1
+Proteasome, subunit alpha/beta [IPR001353]	0.5483793494132454	1.1476171761387024	0.2511266359491957	1.0	0.2713609013181706	14	P28072,P49721	2
+Sister chromatid cohesion protein Pds5 [IPR039776]	0.630762953896371	1.1185489872140526	0.2633325966894	1.0	0.2839235816728223	2	Q9NTI5	1
+Fumarate lyase family [IPR000362]	0.6128110975112225	1.0386982243072451	0.298945107265685	1.0	0.3202048796642293	2	P07954	1
+Importin beta family [IPR040122]	0.6798693344222025	1.0188325885602914	0.3082824514961508	1.0	0.3293055319309674	4	Q8TEX9,Q14974,O00410	3
+Septin [IPR016491]	0.651020408163262	0.8998042487799076	0.3682244328944235	1.0	0.3905652435575737	3	Q16181,Q15019	2
+Beta tubulin [IPR002453]	0.647284226753204	0.8953518470013279	0.3705990328579616	1.0	0.3926584990995069	4	Q9BUF5,P68371	2
+Tubulin [IPR000217]	0.6472842267532041	0.8953518470013279	0.3705990328579616	1.0	0.3926584990995069	4	Q9BUF5,P68371	2
+P-type ATPase [IPR001757]	0.6338890394308648	0.8748449833693627	0.3816582575236689	1.0	0.4041573111040257	5	P20020,Q9HD20	2
+cAMP-dependent protein kinase regulatory subunit [IPR012198]	0.5675234598123262	0.8408496680166104	0.4004321582060826	1.0	0.4231225935064812	2	P10644	1
+Adenylate kinase/UMP-CMP kinase [IPR000850]	0.6237074509132184	0.7967947918201885	0.4255702203707314	1.0	0.4482337232307112	3	P00568	1
+14-3-3 protein [IPR000308]	0.599906925792536	0.7512313710685726	0.4525134234476908	1.0	0.4753333063897954	6	P27348	1
+Vinculin/alpha-catenin [IPR006077]	0.5442676458588388	0.7423626724236888	0.4578676291964723	1.0	0.4799276327444822	2	P35221	1
+Ran binding protein RanBP1-like [IPR045255]	0.5928084681487696	0.6951062619995125	0.486988710724535	1.0	0.5096332953493531	4	P43487	1
+Ras GTPase-activating protein-binding protein [IPR039539]	0.5259077927376575	0.6667483985455978	0.5049328583450836	1.0	0.5270034843495063	2	Q13283	1
+Monothiol glutaredoxin-related [IPR004480]	0.522235822113424	0.6518932728205554	0.5144700249499663	1.0	0.5366714485093416	2	Q86SX6	1
+Ribosomal protein S5/S7 [IPR000235]	0.4985720114239117	0.5586668312686626	0.5763891201219409	1.0	0.5999839963842425	2	P46782	1
+GDP dissociation inhibitor [IPR018203]	0.4957160342717251	0.5477387716837628	0.5838712858039077	1.0	0.6064827467395497	2	P50395	1
+Rab GDI protein [IPR000806]	0.4957160342717251	0.5477387716837628	0.5838712858039077	1.0	0.6064827467395497	2	P50395	1
+Ribosomal protein L3 [IPR000597]	0.4887800897592868	0.5215199899447817	0.6020045838370467	1.0	0.6236640080174272	2	P09001	1
+Calponin/LIMCH1 [IPR001997]	0.4777641778865791	0.4808700992874017	0.6306088250918183	1.0	0.6512299997519938	2	Q15417	1
+Eukaryotic translation initiation factor 3 subunit M eIF3m/COP9 signalosome complex subunit 7 COPS7 [IPR045237]	0.4753161974704221	0.4720116068706815	0.6369185038836456	1.0	0.6570529139115796	2	Q7L2H7	1
+ThiF/MoeB/HesA family [IPR045886]	0.5071268664843234	0.4350045223410287	0.6635591448736249	1.0	0.6823785744026037	5	Q8TBC4	1
+Serine-tRNA ligase, type1 [IPR002317]	0.461036311709507	0.4216990392003851	0.6732447058444033	1.0	0.691575414393199	2	Q9NP81	1
+Alanine-tRNA ligase, eukaryota/bacteria [IPR023033]	0.4606283149734817	0.420297181290826	0.6742683687827462	1.0	0.691575414393199	2	Q5JTZ9	1
+Alanine-tRNA ligase, class IIc [IPR002318]	0.4606283149734817	0.420297181290826	0.6742683687827462	1.0	0.691575414393199	2	Q5JTZ9	1
+Porin, eukaryotic type [IPR001925]	0.4991836734693838	0.3754487550359286	0.7073267510538759	1.0	0.7232092838451639	3	P45880,P21796	2
+Protein phosphatase 2C family [IPR015655]	0.431660546715627	0.3263530009694156	0.7441572923142696	1.0	0.7588854053913229	2	Q9H0C8	1
+Arginine-tRNA ligase [IPR001278]	0.4275805793553642	0.3140684388343496	0.7534690597378884	1.0	0.7675819037288166	2	Q5T160	1
+Aminopeptidase, leukotriene A4 hydrolase-like [IPR034015]	0.4145246838025315	0.2764610776086914	0.7821939506516264	1.0	0.7951899041411654	2	P09960	1
+Transmembrane emp24 domain-containing protein [IPR015720]	0.4594631540919746	0.268819642151539	0.7880684772918114	1.0	0.8007462784314305	3	Q9BVK6	1
+Pre-mRNA-splicing factor Syf1-like [IPR045075]	0.4351020408163207	0.2127585372266961	0.8315153057575184	1.0	0.8434385842794382	3	Q9HCS7,Q9BZJ0	2
+Fimbrin/Plastin [IPR039959]	0.3729090167278656	0.175239908932909	0.8608911266959756	1.0	0.8715743671513547	2	Q14651	1
+Nucleolar, Nop52 [IPR010301]	0.3676050591595245	0.1644832137240363	0.8693507602807724	1.0	0.8796841284908281	2	Q14684	1
+Valine-tRNA ligase [IPR002303]	0.3663810689514462	0.1620710881954683	0.8712498734387328	1.0	0.8809877062373388	2	Q5ST30	1
+Importin subunit alpha [IPR024931]	0.401388321763988	0.1525888666672217	0.8787225052914058	1.0	0.8877908489992635	4	P52294,O00629,P52292	3
+DNA mismatch repair MutS family [IPR045076]	0.3963265306122401	0.1396936362429354	0.8889020546466575	1.0	0.8971495994835852	3	P52701,P20585	2
+RuvB-like [IPR027238]	0.348837209302327	0.1303831672776691	0.8962632834708288	1.0	0.9031824544703464	2	Q9Y230	1
+HAD-superfamily hydrolase, subfamily IIA [IPR006357]	0.3370053039575644	0.1120224859347764	0.9108055775886612	1.0	0.9164220559705027	2	Q9BXW7	1
+Filamin family [IPR044801]	0.3746938775510156	0.107783347468211	0.9141675527228998	1.0	0.9188604046362618	3	Q14315,O75369	2
+Ribosome biogenesis protein Bms1/Tsr1 [IPR039761]	0.3243574051407527	0.0949920141759833	0.9243211700019444	1.0	0.9285894565745548	2	Q2NL82	1
+Clathrin adaptor, mu subunit [IPR001392]	0.2975510204081585	0.0406692397107033	0.9675595844528986	1.0	0.9700366955242066	3	Q96CW1,Q9Y2T2	2
+Small GTPase [IPR001806]	0.2802370788220601	0.0287618638927673	0.977054516492364	1.0	0.9780535497403112	24	Q3YEC7,P84095,P11233,Q969Q5	4