| Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size |
| Ferroptosis 0.7470948799774436 2.972056185522856 0.0029581254464823 0.8174042096889745 0.498600633099489 18 P16435,Q658P3,P37268,P09601,P45880 5 |
| Sphingolipid metabolism in senescence 0.8102980126771968 2.555730842332755 0.0105965049018204 0.997790191352486 0.498600633099489 9 Q06136,Q96G23,Q13510,P04062 4 |
| Cholesterol metabolism with bloch and kandutschrussell pathways 0.6720329876752693 2.529114263459937 0.0114350792704571 0.9986417422803708 0.498600633099489 18 P48449,P37268,Q9UBM7,P14324,O00767,O95864,Q14739,Q16850,Q14534 9 |
| Oxidation by cytochrome p450 0.9266991549211936 2.5185904412144016 0.011782561953304 0.998889949960774 0.498600633099489 5 O43169,Q16850 2 |
| Sphingolipid pathway 0.864936987336451 2.4870153700035473 0.0128819833409954 0.9994140627184692 0.498600633099489 7 Q06136,Q96G23,Q13510,P04062 4 |
| Electron transport chain oxphos system in mitochondria 0.6221259194421286 2.475438596334367 0.0133072642321585 0.9995424608006344 0.498600633099489 40 O00483,O75880,O95168,P00403,P21912,Q9UDW1,P06576,P14406,O43676,Q9Y6M9,P05141,O75964,P22695,P12235,P12236,O14949,P20674,P24539,P56385,O75306,P56134,P13073 22 |
| Sphingolipid metabolism integrated pathway 0.8783055862742736 2.316703689805434 0.0205198784441584 0.9999932159414392 0.498600633099489 5 Q06136,Q96G23,Q13510 3 |
| Sphingolipid metabolism overview 0.8783055862742736 2.316703689805434 0.0205198784441584 0.9999932159414392 0.498600633099489 5 Q06136,Q96G23,Q13510 3 |
| Overlap between signal transduction pathways contributing to lmna laminopathies 0.7078397897243079 2.27873786998812 0.0226826521483833 0.9999980926128068 0.498600633099489 13 P42167,P55209,P02545,P50402,O60725,O75844,Q9Y2U8 7 |
| Influence of laminopathies on wnt signaling 0.7317026944275059 2.175917450843366 0.0295614336784184 0.999999966912855 0.498600633099489 9 O60725,P02545 2 |
| Photodynamic therapyinduced nfe2l2 nrf2 survival signaling 0.9153583596030036 2.1739122376024 0.0297117268210505 0.9999999697274368 0.498600633099489 4 P09601 1 |
| Mitochondrial complex iv assembly 0.7171533124963854 2.090831470636147 0.0365431739433945 0.9999999994755356 0.498600633099489 10 P14406,Q9Y2R0,P13073 3 |
| Cholesterol biosynthesis with skeletal dysplasias 0.8225037530570914 2.078074518496034 0.0377024962015262 0.9999999997372322 0.498600633099489 5 Q9UBM7,Q14739,Q16850 3 |
| Cholesterol biosynthesis pathway 0.7112233901821338 2.073995354518454 0.038079742298771 0.9999999997901896 0.498600633099489 9 Q9UBM7,P37268,P14324,Q16850,Q14534 5 |
| Nonalcoholic fatty liver disease 0.5695506782054666 2.037511325896042 0.0415988281299439 0.999999999974404 0.498600633099489 37 O00483,O75306,P20674,P00403,P22695,Q86Y39,P21912,P31751,Q9UDW1,P13073,O14949,P14406,O43676,Q9NX14,Q9Y6M9 15 |
| 7oxoc and 7betahc pathways 0.7646724781027832 2.0341518428111955 0.0419362882712566 0.9999999999790888 0.498600633099489 7 Q9UBM7,O15118 2 |
| Familial partial lipodystrophy fpld 0.7576168834638394 2.0013804992012543 0.0453514005716493 0.9999999999973072 0.498600633099489 7 P02545,O60725,O75844,P31751,P20700 5 |
| Ketogenesis and ketolysis 0.8673304380000111 1.9770149833434063 0.048039936575023 0.9999999999994664 0.498600633099489 4 O43772,P23786 2 |
| Alzheimers disease and mirna effects 0.4390656161414056 1.960070374416126 0.049987565369038 0.9999999999998354 0.498600633099489 70 P05141,Q96IX5,P20618,P05067,Q9Y277,P12235,P28072,P68371,P21796,P12236,P16615,Q92542,P07437,P45880,Q9NQC3,O95197,P49721,Q9NSK0 18 |
| Mitochondrial complex iii assembly 0.8047093530078772 1.9267331627077635 0.0540128927576608 0.9999999999999856 0.498600633099489 6 Q6DKK2,Q9UDW1,O14949 3 |
| Metabolism of spingolipids in er and golgi apparatus 0.9396164830681376 1.8987394898960688 0.057598736627813 0.9999999999999984 0.498600633099489 3 Q06136,O95470 2 |
| Degradation pathway of sphingolipids including diseases 0.7246468810161966 1.8466999357223428 0.064790641029655 1.0 0.498600633099489 7 P17900,P16278 2 |
| Statin inhibition of cholesterol production 0.923296613627094 1.833727195123556 0.0666944996443081 1.0 0.498600633099489 3 P37268,Q8WTV0 2 |
| Alzheimers disease 0.4315602932721035 1.8248714281811451 0.0680204337643661 1.0 0.498600633099489 69 P05141,P20618,P05067,Q9Y277,P12235,P28072,P68371,P21796,P12236,P16615,Q92542,P07437,P45880,Q9NQC3,O95197,P49721,Q9NSK0 17 |
| Vitamin d metabolism 0.910648714810284 1.7831453782664193 0.074562641248741 1.0 0.5113115938444643 3 Q9UBM7,P04062 2 |
| Nephrotic syndrome 0.6389498983412486 1.7542168119344632 0.0793933635706194 1.0 0.5113115938444643 11 O75844,Q14108,P02545 3 |
| Glycerophospholipid biosynthetic pathway 0.80412255754018 1.7125001393927397 0.0868045389452429 1.0 0.5244821616270471 4 P48651,O00116 2 |
| Mitochondrial immune response to sarscov2 0.6910395756315583 1.6864988099727989 0.091699764106091 1.0 0.5411049572941292 7 P35232,Q99623,Q9Y6M9,Q9Y375 4 |
| Acquired partial lipodystrophy barraquersimons syndrome 0.7971428571428549 1.682955154471584 0.0923837731965586 1.0 0.5411049572941292 4 O60725,P02545,P20700 3 |
| Progeriaassociated lipodystrophy 0.6308575990583019 1.6622698695443898 0.0964586762745942 1.0 0.5411220640908193 9 O60725,P02545 2 |
| Kennedy pathway from sphingolipids 0.792244897959182 1.6621864614035518 0.0964753937286619 1.0 0.5411220640908193 4 Q9UG56,P48651,O95470 3 |
| Copper homeostasis 0.7252485521155515 1.577093216506397 0.1147740778476826 1.0 0.5589540703504077 6 Q658P3,P05067 2 |
| Eicosanoid metabolism via lipooxygenases lox 0.766938775510202 1.5544486734566103 0.1200774306945231 1.0 0.567802102311194 4 Q14914,Q8N8N7,P09960 3 |
| Vasopressinregulated water reabsorption 0.5749939902330611 1.537883650709818 0.1240770654870777 1.0 0.5681436084231606 13 P61020,Q13561,Q9UJW0 3 |
| Mitochondrial complex i assembly model oxphos system 0.5171505050303248 1.53375785554908 0.1250892346213539 1.0 0.5681436084231606 19 O75306,O95168,Q8IUX1,Q9P032,Q9Y375,O43676,Q9NPL8,Q9NX14,Q9Y6M9 9 |
| Oxidative phosphorylation 0.5164562891642385 1.531263640403333 0.1257042478566923 1.0 0.5681436084231606 22 O00483,Q15904,O75306,O95168,O75964,Q86Y39,P24539,P56134,P06576,P56385,Q9Y6M9 11 |
| Genes related to primary cilium development based on crispr 0.6020241413373788 1.5224403285750925 0.1278987863366187 1.0 0.5691000260249548 8 O95684,Q7Z4L5,Q10713 3 |
| S1p receptor signal transduction 0.7547825633362377 1.5024651334749992 0.1329770260024132 1.0 0.5871447148106553 4 Q13510 1 |
| Amyotrophic lateral sclerosis als 0.6461277329429644 1.4687845081595614 0.1418912472772575 1.0 0.6123727514071114 7 O96008,Q9BUN8 2 |
| Camkk2 pathway 0.642366420634506 1.4503843745084717 0.1469513619754947 1.0 0.6156940275469633 7 O76024,P09601,Q13501 3 |
| Nanomaterial induced apoptosis 0.7353884307040881 1.4192805664327928 0.1558172354994125 1.0 0.6254482040326068 4 O43464,O95831 2 |
| Endothelin pathways 0.6804341393452902 1.3755045222362794 0.1689750846808237 1.0 0.6394793933033307 6 P16615,P42892 2 |
| Glycerolipids and glycerophospholipids 0.8089067588410996 1.37164004067127 0.1701755224886767 1.0 0.6394793933033307 3 P48651 1 |
| Glycosaminoglycan degradation 0.6781374383029879 1.3651075006428763 0.1722192649285148 1.0 0.6394793933033307 6 P54802,P15586,P07686,P16278 4 |
| Metapathway biotransformation phase i and ii 0.4922068321151781 1.3639460987827048 0.1725845306368669 1.0 0.6394793933033307 18 Q16850,P07099,Q8NCH0 3 |
| Allograft rejection 0.6196981399640531 1.339033312710158 0.1805598283323017 1.0 0.6601359328837021 7 P08183,P08670 2 |
| Intracellular trafficking proteins involved in cmt neuropathy 0.664534618675704 1.303424845598372 0.1924297587514432 1.0 0.6682716571692096 6 Q9NR77 1 |
| Proteoglycan biosynthesis 0.95921696574225 1.2484384728831766 0.2118705271702041 1.0 0.6909868329300977 2 Q8TB61 1 |
| Adipogenesis 0.5409891999046782 1.2193470775505353 0.2227124874509032 1.0 0.7033712094590429 11 O75844,O00767,P02545 3 |
| Eicosanoid synthesis 0.9400489396411098 1.1771224545182986 0.2391466339044607 1.0 0.7340650687762593 2 P09960 1 |
| Caloric restriction and aging 0.7581124759633349 1.1652684908152993 0.2439103292841558 1.0 0.7375846969377181 3 P43490 1 |
| Triacylglyceride synthesis 0.7475530381500024 1.1225467689156376 0.2616300338358424 1.0 0.768084794625686 3 O00116 1 |
| Ccl18 signaling pathway 0.6245091260713073 1.1212377008740444 0.2621866958822547 1.0 0.768084794625686 6 Q86UE4,P08670 2 |
| Inclusion body myositis 0.9192495921696588 1.1002019530352032 0.2712441398495029 1.0 0.7707630508594786 2 Q92542 1 |
| Aryl hydrocarbon receptor pathway wp2873 0.6554727296724563 1.0754270322566934 0.2821835845064537 1.0 0.773738916155236 4 Q15185 1 |
| Vitamin d receptor pathway 0.5042902699264182 0.9947941469551742 0.3198363935250987 1.0 0.8052021486114328 8 P08183 1 |
| Nuclear receptors in lipid metabolism and toxicity 0.8874388254486073 0.9838684613417086 0.3251801925210271 1.0 0.8090070525229831 2 P08183 1 |
| Vitamin dsensitive calcium signaling in depression 0.5926024363042748 0.9759716390038372 0.3290785189276497 1.0 0.8090070525229831 6 P20020,Q8NB78 2 |
| Mevalonate arm of cholesterol biosynthesis pathway 0.5359473070518415 0.92412955310564 0.3554188681530057 1.0 0.8361083209828905 7 P37268 1 |
| Envelope proteins and their potential roles in edmd physiopathology 0.4588901463683347 0.9062429379161558 0.3648072807679319 1.0 0.8394805490226873 14 P42167,P50402,Q9BTV4,Q14739,P62993 5 |
| Apoptosisrelated network due to altered notch3 in ovarian cancer 0.4755830148256341 0.8972840771122074 0.3695673508312567 1.0 0.8394805490226873 12 P08670,Q13616,P05067 3 |
| Urea cycle and related diseases 0.8601141924959237 0.8856742427823201 0.3757930918488232 1.0 0.8492332075638762 2 Q9UJS0 1 |
| Omega9 fatty acid synthesis 0.569893069164487 0.8731167342785981 0.3825994535509096 1.0 0.8545217367245997 6 O00767 1 |
| Ciliopathies 0.4820879744205347 0.8505975038258834 0.3949929765419329 1.0 0.8599470078954249 10 Q7Z4L5,Q10713 2 |
| Relationship between inflammation cox2 and egfr 0.8364600326264194 0.8023852204988948 0.4223301596854023 1.0 0.8805440735651794 2 Q9H7Z7 1 |
| Histone modifications 0.589099321038155 0.7945736241312309 0.4268615661781818 1.0 0.8805440735651794 4 Q03164,Q01105 2 |
| Eicosanoid metabolism via cyclooxygenases cox 0.5844961787920774 0.7755225107300311 0.4380309690872073 1.0 0.8831319769369472 4 Q14914,Q8N8N7 2 |
| Sterol regulatory elementbinding proteins srebp signaling 0.4082633456723845 0.7565821953128974 0.44930021155352 1.0 0.8884758255998515 24 Q9NR31,P37268,P14324,Q8WTV0,O00767,Q16850,Q14534 7 |
| Glucocorticoid receptor pathway 0.5197062816405664 0.7116803603948657 0.4766627319751282 1.0 0.9059748614361708 5 Q13616 1 |
| Spinal cord injury 0.4199901898950879 0.6660493234758454 0.5053795743457588 1.0 0.9159472663247744 14 Q9NQC3 1 |
| Nad biosynthetic pathways 0.5555452857842844 0.6577146993413329 0.5107214751355571 1.0 0.9159472663247744 4 Q8IXJ6 1 |
| Congenital generalized lipodystrophy cgl 0.7920065252854829 0.6516072706736755 0.5146545561867846 1.0 0.9159472663247744 2 P31751 1 |
| Nad metabolism 0.6213433785972575 0.6308175360687515 0.528159835997204 1.0 0.9228311150392204 3 Q8IXJ6 1 |
| Gastric cancer network 2 0.4207031384231985 0.6225573141861495 0.5335754691860157 1.0 0.9280979373114332 13 Q14739 1 |
| Inhibition of exosome biogenesis and secretion by manumycin a in crpc cells 0.4972552615700782 0.6139456843651637 0.5392512201028663 1.0 0.9292049775629428 5 P61020 1 |
| Male infertility 0.3849618518704547 0.6104100829181017 0.5415901905824723 1.0 0.9292049775629428 19 Q15165 1 |
| Type ii diabetes mellitus 0.7789559543230034 0.6091106022249412 0.5424511305366035 1.0 0.9292049775629428 2 O00330 1 |
| Neuroinflammation 0.7789559543229937 0.609110602224911 0.5424511305366235 1.0 0.9292049775629428 2 P00403 1 |
| Proximal tubule transport 0.4303804608943392 0.5852127624126106 0.5584046645041372 1.0 0.9399538927430344 9 P08183 1 |
| Hedgehog signaling pathway wp4249 0.6020674677640594 0.5615117752739295 0.5744487052772789 1.0 0.941542168601036 3 P48729 1 |
| G1 to s cell cycle control 0.3769630799749904 0.5612760561668718 0.5746093616821555 1.0 0.941542168601036 18 Q14566 1 |
| Preimplantation embryo 0.4541424296600941 0.5291281851061743 0.5967165305490092 1.0 0.9431021289729868 7 P05023 1 |
| Tnfalpha signaling pathway 0.4029484029484193 0.4832952331880462 0.6288861241910777 1.0 0.9483545132608616 12 P63000,Q16543,P63208,Q13616,Q13200,P53350,P07900,P06737,Q9NR28,Q13546,P62993 11 |
| Omega3 omega6 fatty acid synthesis 0.4626157370592685 0.469423768588188 0.6387667622029356 1.0 0.9483545132608616 5 O95864 1 |
| Fluoroacetic acid toxicity 0.4459364856350472 0.4034322690888001 0.6866302518643743 1.0 0.9754193781147952 5 P51648 1 |
| Interactome of polycomb repressive complex 2 prc2 0.5377396980824195 0.3507823890363492 0.7257516102283663 1.0 0.9895045707151598 3 Q9NYF8,Q15022 2 |
| P38 mapk signaling pathway 0.4275214373213595 0.3339927171534211 0.7383850543007286 1.0 0.9958626406359316 5 P60953,P04792,P63000,P62993 4 |
| Hair follicle development cytodifferentiation part 3 of 3 0.52672378620971 0.3186474125920384 0.7499938960051933 1.0 1.0 3 P78536,P35222 2 |
| Hair follicle development organogenesis part 2 of 3 0.526723786209707 0.3186474125920286 0.7499938960052006 1.0 1.0 3 P05556,P35222 2 |
| Interactions between loxl4 and oxidative stress pathway 0.6712887438825462 0.302988752997225 0.7618984327958478 1.0 1.0 2 Q9BQ95 1 |
| Arrhythmogenic right ventricular cardiomyopathy 0.373073557943423 0.3003856109136336 0.7638830380340178 1.0 1.0 11 P02545 1 |
| Hippo signaling regulation pathways 0.3756137479541735 0.2955289311900962 0.7675898548383273 1.0 1.0 10 P13861,P08754,P42345,P60953,P10644,P04899,P17612,P63000,P35222 9 |
| Riboflavin and coq disorders 0.5150674871837051 0.2861289157364283 0.774779385398926 1.0 1.0 3 Q16134 1 |
| Ranklrank signaling pathway 0.4286142866701645 0.2812502095629718 0.7785184964929186 1.0 1.0 6 P31751,Q13501 2 |
| Alpha 6 beta 4 signaling pathway 0.4459462498414336 0.2662454707828228 0.7900501657548098 1.0 1.0 4 P62993 1 |
| Apoptosis modulation and signaling 0.3691693623607855 0.2649840455258967 0.7910217524495105 1.0 1.0 10 O43464,O95831 2 |
| Notch signaling pathway 0.352368338446689 0.2175891534783905 0.827749236289776 1.0 1.0 12 Q92542 1 |
| Circadian rhythm genes 0.3317143051514335 0.1843349635586841 0.8537506869104265 1.0 1.0 36 Q8WXF1,Q14103,P43490,Q03164,Q13616,Q9UNS1,P23246,P54802,Q9NRV9,Q15233 10 |
| Fatty acid transporters 0.4102040816326495 0.1682612949452515 0.8663777218430024 1.0 1.0 4 O95573,Q6P1M0,P33121 3 |
| Dna replication 0.3207072687448802 0.1623372247016638 0.8710403023707194 1.0 1.0 22 P33993,Q14566,P41440,P40938,P33991,Q9Y619 6 |
| Tnfrelated weak inducer of apoptosis tweak signaling pathway 0.3901143790849695 0.1520374512188655 0.8791573971940718 1.0 1.0 6 Q13546,P31751,Q13547,P63000,P35222 5 |
| Mitochondrial long chain fatty acid betaoxidation 0.3378301804240341 0.1481030864760188 0.8822614136545743 1.0 1.0 12 O43772 1 |
| Mirna biogenesis 0.4553243574051416 0.1462703711784371 0.8837079546413791 1.0 1.0 3 Q8WYQ5,P62826 2 |
| Microrna network associated with chronic lymphocytic leukemia 0.5860522022838576 0.1372989742634821 0.8907944811781403 1.0 1.0 2 Q07820 1 |
| Folate metabolism 0.326392680273835 0.1114841539918938 0.9112324305483716 1.0 1.0 13 P41440,P00374,Q8WTV0 3 |
| Cannabinoid receptor signaling 0.5477161500815708 0.0883312576488102 0.9296133960338392 1.0 1.0 2 P17612 1 |
| Tcell antigen receptor tcr pathway during staphylococcus aureus infection 0.3674409019129638 0.0866853981352773 0.9309215833227362 1.0 1.0 6 O95433,P62993 2 |
| Nrf2 pathway 0.3040707819868195 0.0864261719079805 0.931127642591022 1.0 1.0 19 P09601,Q99735,O14880,Q9H2J7 4 |
| H19 action rbe2f1 signaling and cdkbetacatenin activity 0.3688977819865574 0.0796229816368286 0.9365371165418526 1.0 1.0 4 Q16527 1 |
| Ciliary landscape 0.2699872777737916 0.0772020699529677 0.9384627949792248 1.0 1.0 83 O75663,O95721,P16278,Q92600,Q13409,O43464,Q15024,Q7L5N1,O60645,A0AVF1,O15173,Q96PK6,P07197,Q14566,Q9HDC9,P10619,P08670,P33991,Q92905,P33993,Q9BT78 21 |
| Microglia pathogen phagocytosis pathway 0.5314029363784755 0.0720610173246286 0.94255334920572 1.0 1.0 2 O15143 1 |
| Tryptophan metabolism 0.3133230248603686 0.0686492439554604 0.9452688202851944 1.0 1.0 14 P05091,P51648,Q15392 3 |
| Photodynamic therapyinduced ap1 survival signaling 0.3616326530612183 0.0669064173370262 0.946656204192504 1.0 1.0 4 P04637,Q07820,P07900 3 |
| Robo4 and vegf signaling pathways crosstalk 0.523654159869505 0.0652231870540676 0.947996299833742 1.0 1.0 2 P63000 1 |
| Insulin signaling in adipocytes diabetic condition 0.3513060856694954 0.050307583043795 0.9598772810281382 1.0 1.0 4 P31751 1 |
| Insulin signaling in adipocytes normal condition 0.3513060856694954 0.050307583043795 0.9598772810281382 1.0 1.0 4 P31751 1 |
| Regulation of wnt bcatenin signaling by small molecule compounds 0.3896368829049366 0.0486093907487894 0.9612305860784524 1.0 1.0 3 P48729,P35222 2 |
| T cell receptor and costimulatory signaling 0.3896368829049357 0.0486093907487889 0.9612305860784528 1.0 1.0 3 P49840,P48729 2 |
| Cellular proteostasis 0.3497959183673416 0.0480240426796212 0.961697081423083 1.0 1.0 4 Q9UHV9,P61758,Q99471 3 |
| Nad metabolism sirtuins and aging 0.3816072915342499 0.0405616617993999 0.9676453484394164 1.0 1.0 3 P43490 1 |
| Exrna mechanism of action and biogenesis 0.4551386623164773 0.025865980191598 0.97936423483685 1.0 1.0 2 Q8WYQ5 1 |
| Purinergic signaling 0.4371941272430782 0.0204997074445034 0.9836447454536684 1.0 1.0 2 P04899 1 |
| Apoptosis 0.3208009807928082 0.0202247095835814 0.9838641165179822 1.0 1.0 7 Q07820,P04637,Q9NRZ9,Q9NR28,Q13546,P49327 6 |
| Synaptic signaling pathways associated with autism spectrum disorder 0.3117073172180729 0.015735638170697 0.9874452953637404 1.0 1.0 5 P31751 1 |
| Hepatitis b infection 0.3039410856860298 0.0124325762451365 0.9900804949049108 1.0 1.0 13 Q9Y277,Q15904,P31751 3 |
| Regucalcin in proximal tubule epithelial kidney cells 0.3772430668841781 0.0113356243283941 0.9909556740555834 1.0 1.0 2 P42345 1 |
| Complement system in neuronal development and plasticity 0.3356859206735734 0.010568465747548 0.991567741318914 1.0 1.0 6 O43464 1 |
| Ovarian infertility 0.3115823817291976 0.0089517674431451 0.9928576183567795 1.0 1.0 2 P11802 1 |
| Mechanoregulation and pathology of yaptaz via hippo and nonhippo mechanisms 0.332516339869283 0.004006897414144 0.9968029669713844 1.0 1.0 6 O96013,P35221,Q13177,P05556,P35222 5 |
|
|
