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  1. interpro_active_site/advanced/idx2term.json +1 -0
  2. interpro_active_site/basic/idx2term.json +1 -0
  3. interpro_active_site/consensus.joblib +3 -0
  4. interpro_active_site/df_merge.tsv +1 -0
  5. interpro_active_site/metrics.json +7 -0
  6. interpro_active_site/paths.json +1 -0
  7. interpro_active_site/result.tsv +7 -0
  8. interpro_active_site/selections.json +1 -0
  9. interpro_binding_site/advanced/idx2term.json +1 -0
  10. interpro_binding_site/advanced/plot_0.png +3 -0
  11. interpro_binding_site/basic/idx2term.json +1 -0
  12. interpro_binding_site/basic/plot_0.png +3 -0
  13. interpro_binding_site/consensus.joblib +3 -0
  14. interpro_binding_site/df_merge.tsv +2 -0
  15. interpro_binding_site/metrics.json +7 -0
  16. interpro_binding_site/paths.json +1 -0
  17. interpro_binding_site/result.tsv +5 -0
  18. interpro_binding_site/selections.json +1 -0
  19. interpro_conserved_site/advanced/idx2term.json +1 -0
  20. interpro_conserved_site/advanced/plot_0.png +3 -0
  21. interpro_conserved_site/basic/idx2term.json +1 -0
  22. interpro_conserved_site/basic/plot_0.png +3 -0
  23. interpro_conserved_site/consensus.joblib +3 -0
  24. interpro_conserved_site/df_merge.tsv +3 -0
  25. interpro_conserved_site/metrics.json +7 -0
  26. interpro_conserved_site/paths.json +1 -0
  27. interpro_conserved_site/result.tsv +28 -0
  28. interpro_conserved_site/selections.json +1 -0
  29. interpro_domain/advanced/idx2term.json +1 -0
  30. interpro_domain/advanced/plot_0.png +3 -0
  31. interpro_domain/basic/idx2term.json +1 -0
  32. interpro_domain/basic/plot_0.png +3 -0
  33. interpro_domain/basic/plot_1.png +3 -0
  34. interpro_domain/basic/plot_2.png +3 -0
  35. interpro_domain/basic/plot_3.png +3 -0
  36. interpro_domain/basic/plot_4.png +3 -0
  37. interpro_domain/consensus.joblib +3 -0
  38. interpro_domain/df_merge.tsv +5 -0
  39. interpro_domain/metrics.json +7 -0
  40. interpro_domain/paths.json +1 -0
  41. interpro_domain/result.tsv +145 -0
  42. interpro_domain/selections.json +0 -0
  43. interpro_family/advanced/idx2term.json +1 -0
  44. interpro_family/advanced/plot_0.png +3 -0
  45. interpro_family/advanced/plot_1.png +3 -0
  46. interpro_family/basic/idx2term.json +1 -0
  47. interpro_family/basic/plot_0.png +3 -0
  48. interpro_family/basic/plot_1.png +3 -0
  49. interpro_family/basic/plot_2.png +3 -0
  50. interpro_family/basic/plot_3.png +3 -0
interpro_active_site/advanced/idx2term.json ADDED
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+ {}
interpro_active_site/basic/idx2term.json ADDED
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+ {}
interpro_active_site/consensus.joblib ADDED
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+ size 62629
interpro_active_site/df_merge.tsv ADDED
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+ term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500
interpro_active_site/metrics.json ADDED
@@ -0,0 +1,7 @@
 
 
 
 
 
 
 
 
1
+ {
2
+ "type_of_task": "ranksum",
3
+ "signature_size": 2454,
4
+ "annotations_size": 50,
5
+ "title": "Average number of proteins per term",
6
+ "value": 2.3
7
+ }
interpro_active_site/paths.json ADDED
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+ {"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C340/C340_val_log2fc"}
interpro_active_site/result.tsv ADDED
@@ -0,0 +1,7 @@
 
 
 
 
 
 
 
 
1
+ Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
2
+ Serine carboxypeptidase, serine active site [IPR018202] 0.9673602611179124 1.831329934829985 0.0670513121898026 0.96889086682721 0.1457637221517448 3 Q9HB40,Q9H3G5 2
3
+ Histidine acid phosphatase active site [IPR033379] 0.8054649265905265 1.4542303762481574 0.1458824459505403 0.9996233982058736 0.2515214585354144 2 P11117 1
4
+ Ubiquitin-conjugating enzyme, active site [IPR023313] 0.6481375317504068 1.200462870417974 0.2299596244047284 0.999997883224216 0.3616772089779527 6 Q16763 1
5
+ Cysteine peptidase, cysteine active site [IPR000169] 0.6193390452876388 0.5235844503798823 0.6005675990669668 1.0 0.6970860879653368 3 Q13867,P17655 2
6
+ Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345] 0.4804241435562917 0.2323689299772647 0.8162514788022606 1.0 0.8355808896618625 2 Q9NQ88 1
7
+ Tyrosine-protein kinase, active site [IPR008266] 0.457772337821298 0.1200696217327232 0.9044279966079762 1.0 0.9044279966079762 3 Q15375,P41240 2
interpro_active_site/selections.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {"all_annotations": ["ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenylosuccinate synthase, active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Cysteine peptidase, cysteine active site [IPR000169]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycoside hydrolase, family 2, active site [IPR023232]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]", "Uracil-DNA glycosylase, active site [IPR018085]"], "available_proteins": ["ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADSS", "AKT2", "APEH", "ATP5A1", "ATP5B", "ATP6V1A", "ATP6V1B2", "BLMH", "CAMK2D", "CAMK2G", "CAPN1", "CAPN2", "CDC34", "CDK1", "CDK12", "CDK2", "CDK4", "CDK5", "CDK6", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CTSA", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "EPHA7", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLUD1", "GSK3A", "GSK3B", "GSR", "GUSB", "HADHB", "HMGCL", "HMGCS1", "LDHA", "LDHB", "LONP1", "MAP2K1", "MARK2", "MDH1", "MDH2", "MTMR6", "NEK9", "NME1", "PAK2", "PBK", "PGAM1", "PKM", "PKN2", "PLK1", "PREP", "PRKACA", "PRPF4B", "PTK7", "PTPN1", "RIPK1", "RNASET2", "ROCK2", "RPS6KA1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SRPK2", "SUCLG1", "TALDO1", "TIGAR", "TOP1", "TPI1", "TPP2", "TTK", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "UMPS", "UNG", "VRK1"], "leading_proteins": ["ACP2", "BLMH", "CAPN2", "CPVL", "CSK", "EPHA7", "SCPEP1", "TIGAR", "UBE2S"]}
interpro_binding_site/advanced/idx2term.json ADDED
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+ {"0": "EF-Hand 1, calcium-binding site [IPR018247]"}
interpro_binding_site/advanced/plot_0.png ADDED

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interpro_binding_site/basic/idx2term.json ADDED
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interpro_binding_site/basic/plot_0.png ADDED

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interpro_binding_site/df_merge.tsv ADDED
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+ term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500
2
+ EF-Hand 1, calcium-binding site [IPR018247] 9 32 2.362191464775633 0.0181672567178221 10.019417475728156 36.70631067961165 0.9532938980945532 0.3894555773109194 3.76037227687173 3.057484685571999 1.1082350706804749 0.3408841825650379 1.0 0.0551599902794207 0.1786715045389017 0.0028924350901622 0.001316772075281
interpro_binding_site/metrics.json ADDED
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+ {
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+ "type_of_task": "ranksum",
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+ "signature_size": 2454,
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+ "annotations_size": 27,
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+ "title": "Average number of proteins per term",
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+ "value": 4.111111111111111
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+ }
interpro_binding_site/paths.json ADDED
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+ {"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C340/C340_val_log2fc"}
interpro_binding_site/result.tsv ADDED
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+ Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
2
+ EF-Hand 1, calcium-binding site [IPR018247] 0.5710253232717362 2.362191464775633 0.0181672567178221 0.3904451283227663 0.0922401639565371 32 Q02818,Q9Y680,Q9BRK5,P80303,P30626,Q6NUK1,Q14257,Q9NWM8,O43852 9
3
+ Beta tubulin, autoregulation binding site [IPR013838] 0.9726530612244896 2.317108644920705 0.0204978142125638 0.4283291394202846 0.0922401639565371 4 Q9BUF5,P07437,P68371 3
4
+ Peptidase M16, zinc-binding site [IPR001431] 0.6775130296815998 1.238363984782448 0.2155811284974353 0.998578336214912 0.3499096454543592 5 O43847 1
5
+ Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798] 0.5469004893964198 0.4199294669115569 0.6745369806684534 0.9999999999999312 0.7284999391219297 2 P34897 1
interpro_binding_site/selections.json ADDED
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+ {"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Protein kinase, ATP binding site [IPR017441]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]", "Ureohydrolase, manganese-binding site [IPR020855]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "AKT2", "APEX1", "ARG2", "CALU", "CAMK2D", "CAMK2G", "CAPN1", "CAPN2", "CDK1", "CDK12", "CDK2", "CDK4", "CDK5", "CDK6", "COX2", "COX5B", "CSK", "CSNK1A1", "CYB5B", "DLAT", "DLST", "DST", "EHD1", "EIF2AK2", "EPHA7", "FKBP10", "FKBP14", "FKBP7", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3A", "GSK3B", "HK1", "HK2", "IDE", "ILKAP", "IQGAP1", "LETM1", "MACF1", "MAP2K1", "MARK2", "MCCC1", "METAP2", "MICU1", "MYH10", "MYH14", "MYH9", "MYO1B", "MYO1C", "NRDC", "NUCB1", "NUCB2", "PA2G4", "PAK2", "PAK4", "PC", "PCCA", "PDCD6", "PDHX", "PEF1", "PGD", "PKN2", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "PPM1G", "PRKACA", "PRKCSH", "PSAT1", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK2", "RPS6KA1", "RPS6KA3", "S100A11", "SDF4", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SRI", "SRPK1", "SRPK2", "TKT", "TTK", "TUBB", "TUBB2B", "TUBB4B", "TUBB6", "UBE3C", "UQCRC2", "VRK1"], "leading_proteins": ["CALU", "FKBP14", "FKBP7", "NRDC", "NUCB1", "NUCB2", "RCN2", "SDF4", "SHMT2", "SLC25A24", "SRI", "TUBB", "TUBB4B", "TUBB6"]}
interpro_conserved_site/advanced/idx2term.json ADDED
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interpro_conserved_site/basic/idx2term.json ADDED
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interpro_conserved_site/consensus.joblib ADDED
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interpro_conserved_site/df_merge.tsv ADDED
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+ term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500
2
+ Proteasome beta-type subunit, conserved site [IPR016050] 5 8 2.4991354583278875 0.0124496713168613 3.7135922330097086 7.970873786407767 1.4913184573846054 0.1902243906475925 1.515457478026574 0.1681602725795027 1.0170822776023185 0.2455850375425174 1.0 0.0470522829573702 0.0039921150854813 6.194004931981708e-05 2.1281179634986496e-06
3
+ Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818] 1 5 2.10981464482015 0.0348743245356633 1.8349514563106797 4.495145631067961 -0.0268416016144192 0.3268992301433215 1.18113888908689 0.4999764345469411 1.4254920509394828 0.309635855483207 1.0 0.0002241871259369 0.0009157120850054 0.0055254488719224 0.0209220238917207
interpro_conserved_site/metrics.json ADDED
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+ {
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+ "type_of_task": "ranksum",
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+ "signature_size": 2454,
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+ "annotations_size": 252,
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+ "title": "Average number of proteins per term",
6
+ "value": 2.488095238095238
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+ }
interpro_conserved_site/paths.json ADDED
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+ {"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C340/C340_val_log2fc"}
interpro_conserved_site/result.tsv ADDED
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+ Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
2
+ Proteasome beta-type subunit, conserved site [IPR016050] 0.8481977032997318 2.4991354583278875 0.0124496713168613 0.9574472192309592 0.0825609782065543 8 P28070,P28072,P20618,P49721,Q99436 5
3
+ Tubulin, conserved site [IPR017975] 0.9726530612244896 2.317108644920705 0.0204978142125638 0.9945879327175782 0.1033089836313215 4 Q9BUF5,P07437,P68371 3
4
+ Haem oxygenase conserved site [IPR018207] 0.991435562805872 2.2395010215982603 0.0251233349237796 0.9983582080193628 0.1090679488452607 2 P30519 1
5
+ Sterol reductase, conserved site [IPR018083] 0.963295269168024 2.1231837101527073 0.0337384604655155 0.999824667364121 0.1371305167308051 2 Q14739 1
6
+ Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818] 0.8873152080167173 2.10981464482015 0.0348743245356633 0.9998696427794048 0.1394972981426532 5 P48735 1
7
+ 3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180] 0.9396411092985296 2.0245803127813957 0.04291047749655 0.999984149403687 0.1501866712379252 2 Q16836 1
8
+ Guanylate kinase, conserved site [IPR020590] 0.9102773246329496 1.901198589597285 0.0572760057708205 0.9999996493213344 0.178192017953664 2 Q14168 1
9
+ Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364] 0.8036526172755745 1.6442491194120992 0.1001247545498675 0.999999999997156 0.2498162192729369 4 Q8N4Q0 1
10
+ Profilin conserved site [IPR027310] 0.7993474714518656 1.4279710796467522 0.1533001828542315 1.0 0.3192698023079863 2 P07737 1
11
+ Clathrin adaptor complex, small chain [IPR000804] 0.7944535073409462 1.4069631466221186 0.159438317092758 1.0 0.3274420832091019 2 P61923 1
12
+ Chromo domain, conserved site [IPR023779] 0.8494492044063684 1.37645728993164 0.1686801015807824 1.0 0.3320889499871653 3 Q13185,P83916 2
13
+ 14-3-3 protein, conserved site [IPR023409] 0.6347601898743878 1.1426666095990483 0.2531770382339848 1.0 0.4245067897375093 6 P61981,P27348,Q04917 3
14
+ Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326] 0.7096247960848292 1.0451239726075388 0.2959656757463005 1.0 0.4439485136194507 2 P24534 1
15
+ Actin, conserved site [IPR004001] 0.745716029689144 0.9765435175338548 0.3287951935941045 1.0 0.4704558601695137 3 P61163 1
16
+ Annexin repeat, conserved site [IPR018252] 0.5712647991307751 0.791453646671129 0.4286793152489159 1.0 0.553762970714589 5 P20073,P04083,P50995 3
17
+ Thioredoxin, conserved site [IPR017937] 0.4461416946817904 0.6812651528898246 0.4957037287425352 1.0 0.6063948526364994 10 Q8IXB1,Q9H1E5,P07237 3
18
+ Short-chain dehydrogenase/reductase, conserved site [IPR020904] 0.4479156976000573 0.6519683230489928 0.5144216075444854 1.0 0.6086114793484053 9 Q8NBN7,Q06136 2
19
+ Aldehyde dehydrogenase, glutamic acid active site [IPR029510] 0.4745324682478 0.5984465917620672 0.5495419853778523 1.0 0.6294753650691762 7 O94788,P51648,P30837 3
20
+ HMG box A DNA-binding domain, conserved site [IPR017967] 0.6028333047387474 0.4706184247695404 0.6379132478198473 1.0 0.7019831373388712 3 P26583 1
21
+ Aldehyde dehydrogenase, cysteine active site [IPR016160] 0.4348979185660808 0.4337198266231595 0.6644919072830191 1.0 0.7280520027622644 7 O94788,P51648,P30837 3
22
+ Dynamin, GTPase region, conserved site [IPR019762] 0.5097879282218654 0.3080940396808397 0.7580107764364625 1.0 0.809401337550799 2 O00429 1
23
+ ABC transporter-like, conserved site [IPR017871] 0.3360751075974014 0.1711004517138927 0.8641447806939491 1.0 0.8998464371225551 9 P08183 1
24
+ Syntaxin/epimorphin, conserved site [IPR006012] 0.4818441452468384 0.1612766362946302 0.8718755239001781 1.0 0.8998464371225551 3 Q86Y82,Q9P2W9 2
25
+ Calreticulin/calnexin, conserved site [IPR018124] 0.4802121583027315 0.1582512317858274 0.8742588351992797 1.0 0.8998464371225551 3 O14967,P27797 2
26
+ Adenylate kinase, conserved site [IPR033690] 0.4798041615667128 0.1575001334127116 0.8748507027580397 1.0 0.8998464371225551 3 P00568,P54819 2
27
+ AT hook, DNA-binding motif [IPR017956] 0.4403586849274479 0.0948118560984412 0.9244642694932056 1.0 0.9393749835172897 3 P17096 1
28
+ Ribosomal protein S2, conserved site [IPR018130] 0.3911092985318211 0.0800987456663184 0.9361587203572472 1.0 0.9474377410844428 2 P08865 1
interpro_conserved_site/selections.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Aminotransferase, class IV, conserved site [IPR018300]", "Amyloidogenic glycoprotein, copper-binding domain conserved site [IPR019744]", "Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Bromodomain, conserved site [IPR018359]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific, conserved site [IPR031303]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "Fibrillarin, conserved site [IPR020813]", "Fork head domain conserved site 2 [IPR030456]", "Fork head domain conserved site1 [IPR018122]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 2, conserved site [IPR023230]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "Homeobox, conserved site [IPR017970]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RIO kinase, conserved site [IPR018935]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P, conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "Tyrosine-protein kinase, receptor class V, conserved site [IPR001426]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]"], "available_proteins": ["AAAS", "ABCB1", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ACAA2", "ACAD9", "ACADM", "ACADS", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR1B", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA6", "ANXA7", "AP1M1", "AP2M1", "AP3M1", "AP3S1", "APEX1", "APLP2", "APP", "ARIH2", "ATAD1", "ATP5C1", "ATP5O", "BAG6", "BAZ1A", "BAZ1B", "BAZ2A", "BCAT2", "BLM", "BOP1", "BPTF", "BRCA1", "BRD2", "CAD", "CALR", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CBR1", "CBX1", "CBX3", "CBX5", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDKAL1", "CECR2", "CHAF1B", "CHD4", "CLGN", "CMPK1", "CNDP2", "COPA", "COPZ1", "CORO1B", "CORO1C", "CPOX", "CRYZ", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CYP51A1", "DCAF13", "DCAF7", "DCPS", "DCXR", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX6", "DHCR7", "DHFR", "DHRS7", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX38", "DHX40", "DHX8", "DHX9", "DIDO1", "DIMT1", "DIS3", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC2", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DRG1", "DRG2", "DSG2", "DST", "DTYMK", "DYNLL1", "ECH1", "ECHS1", "ECI2", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4E", "ENO1", "EPB41", "EPB41L2", "EPHA7", "EPRS", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FBL", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FOXC1", "FOXK1", "FUCA2", "GAA", "GALK1", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GLA", "GLB1", "GLO1", "GMPPA", "GNPDA1", "GNS", "GPI", "GRHPR", "GRWD1", "GSPT1", "GTF3C2", "GUSB", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HIBADH", "HINT2", "HLA-A", "HLA-B", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMOX1", "HMOX2", "HOXA10", "HSD17B10", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "ILVBL", "IMPDH2", "INA", "IQGAP1", "IVD", "KDM2A", "KDSR", "KIF11", "KIF14", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFC1", "LAMP1", "LARS", "LARS2", "LBR", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRWD1", "LSS", "MACF1", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME1", "ME2", "MGST2", "MID1", "MIF", "MPI", "MPP2", "MPP6", "MPST", "MRPL24", "MRPL3", "MRPS11", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFV1", "NEFL", "NEFM", "NES", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NSD2", "NSF", "NUBP2", "NUDT1", "NUDT12", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL11", "OSBPL6", "OSBPL9", "P4HB", "PAFAH1B1", "PAICS", "PBRM1", "PCNA", "PDIA3", "PDIA4", "PDIA6", "PEBP1", "PEPD", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHGDH", "PHIP", "PI4KB", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PNP", "PNPLA6", "POLD1", "POLR1B", "POLR1C", "POLR2B", "POLR2E", "PPIB", "PPIC", "PPID", "PPIF", "PPIG", "PPIH", "PPIL1", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PUS7", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "RACK1", "RAE1", "RANBP2", "RARS", "RARS2", "RCL1", "RDH13", "RDX", "RECQL5", "RIOK2", "RNF114", "RNF20", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS24", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "RSF1", "RTN4IP1", "S100A10", "S100A11", "SART1", "SBDS", "SCD", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB6", "SERPINH1", "SLC1A5", "SLC27A4", "SLIT2", "SMARCA4", "SMU1", "SNRNP40", "SNU13", "SPATA5", "SPTBN1", "SRCAP", "SRM", "STMN1", "STRN4", "STX12", "STX18", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SYNE2", "TAP1", "TAP2", "TBL3", "TCP1", "THOC6", "TK1", "TLN1", "TMX1", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRIM25", "TRIM28", "TRIM33", "TRIP13", "TSFM", "TSPAN6", "TUBB", "TUBB2B", "TUBB4B", "TUBB6", "TUFM", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UHRF1", "USP10", "USP14", "USP36", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VARS2", "VAT1", "VCL", "VCP", "VIM", "VPS4B", "WARS", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR3", "WDR36", "WDR5", "WDR61", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2"], "leading_proteins": ["ABCB1", "ACTR1A", "AK1", "AK2", "ALDH1A2", "ALDH1B1", "ALDH3A2", "ANXA1", "ANXA11", "ANXA7", "CALR", "CBX1", "CBX3", "CLGN", "COPZ1", "DNAJC10", "DNM1L", "EEF1B2", "HADH", "HMGA1", "HMGB2", "HMOX2", "IDH2", "KDSR", "LBR", "MPP2", "P4HB", "PFN1", "PSMB1", "PSMB2", "PSMB4", "PSMB6", "PSMB7", "RDH13", "RPSA", "STX12", "STX18", "TMX4", "TUBB", "TUBB4B", "TUBB6", "YWHAG", "YWHAH", "YWHAQ", "ZADH2"]}
interpro_domain/advanced/idx2term.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {"0": "EF-hand domain [IPR002048]"}
interpro_domain/advanced/plot_0.png ADDED

Git LFS Details

  • SHA256: fdef971a1402486b177984e55da616570fc6feab2914b44a9c76066b21d0e4d9
  • Pointer size: 131 Bytes
  • Size of remote file: 197 kB
interpro_domain/basic/idx2term.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {"0": "EF-hand domain [IPR002048]", "1": "RNA recognition motif domain [IPR000504]", "2": "FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]", "3": "DnaJ domain [IPR001623]", "4": "Proteasome component (PCI) domain [IPR000717]"}
interpro_domain/basic/plot_0.png ADDED

Git LFS Details

  • SHA256: fa17298b4a35a77d2b6a4b5d0da6db893d81856d44d08a5da247f1ec22171a7b
  • Pointer size: 131 Bytes
  • Size of remote file: 131 kB
interpro_domain/basic/plot_1.png ADDED

Git LFS Details

  • SHA256: b8858aa1f14684c705e70589a08fb41c478561b0f284d26685d07c1b7f50ad87
  • Pointer size: 131 Bytes
  • Size of remote file: 143 kB
interpro_domain/basic/plot_2.png ADDED

Git LFS Details

  • SHA256: d14f2b8cc36b295c65855e92f7cfb85eccf38d1123f11ab7bfd15b592648ab7c
  • Pointer size: 131 Bytes
  • Size of remote file: 144 kB
interpro_domain/basic/plot_3.png ADDED

Git LFS Details

  • SHA256: c3542690accf3329ac80e317ded11735118ecf75b06b0b9f209353a22d08aae7
  • Pointer size: 131 Bytes
  • Size of remote file: 142 kB
interpro_domain/basic/plot_4.png ADDED

Git LFS Details

  • SHA256: 36b93d3a5b3fd1087c368b6e8cd3c78f93bb1d59cc1dfbf9655f9cbc0c5a8481
  • Pointer size: 131 Bytes
  • Size of remote file: 152 kB
interpro_domain/consensus.joblib ADDED
@@ -0,0 +1,3 @@
 
 
 
 
1
+ version https://git-lfs.github.com/spec/v1
2
+ oid sha256:d73fc3bbe8cd7df3b9aca6ff1224b5c0ad7869ee056ebbe1ddf08b2bbfb7b3af
3
+ size 350648
interpro_domain/df_merge.tsv ADDED
@@ -0,0 +1,5 @@
 
 
 
 
 
 
1
+ term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500
2
+ EF-hand domain [IPR002048] 10 37 2.218680806632741 0.0265084477027324 12.385922330097088 43.512135922330096 1.0171858714399242 0.3947118087831401 4.608360476919044 4.087317384177653 1.201458704248258 0.3652478399429377 1.0 0.0832266786690803 0.2534337902702077 0.0104482115740687 0.0029592657664503
3
+ Isopropylmalate dehydrogenase-like domain [IPR024084] 1 5 2.10981464482015 0.0348743245356633 1.8349514563106797 4.495145631067961 -0.0268416016144192 0.3268992301433215 1.18113888908689 0.4999764345469411 1.4254920509394828 0.309635855483207 1.0 0.0002241871259369 0.0009157120850054 0.0055254488719224 0.0209220238917207
4
+ Aminopeptidase N-like , N-terminal domain [IPR045357] 2 6 2.0476699020294555 0.0405923549015689 2.121359223300971 5.466019417475728 1.4317001483019938 0.1783942022754649 1.021530403905949 0.5881604361499402 0.986353205880356 0.2226891741813114 1.0 0.0378187125466048 4.800413077288208e-05 0.0007102815399137 0.0003159986655096
5
+ Peptidase M1, membrane alanine aminopeptidase [IPR014782] 2 6 2.0476699020294555 0.0405923549015689 2.121359223300971 5.466019417475728 1.4317001483019938 0.1783942022754649 1.021530403905949 0.5881604361499402 0.986353205880356 0.2226891741813114 1.0 0.0378187125466048 4.800413077288208e-05 0.0007102815399137 0.0003159986655096
interpro_domain/metrics.json ADDED
@@ -0,0 +1,7 @@
 
 
 
 
 
 
 
 
1
+ {
2
+ "type_of_task": "ranksum",
3
+ "signature_size": 2454,
4
+ "annotations_size": 2199,
5
+ "title": "Average number of proteins per term",
6
+ "value": 2.050022737608004
7
+ }
interpro_domain/paths.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C340/C340_val_log2fc"}
interpro_domain/result.tsv ADDED
@@ -0,0 +1,145 @@
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
1
+ Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
2
+ Tubulin/FtsZ, 2-layer sandwich domain [IPR018316] 0.9726530612244896 2.317108644920705 0.0204978142125638 1.0 0.0856933335616498 4 Q9BUF5,P07437,P68371 3
3
+ Tubulin/FtsZ, GTPase domain [IPR003008] 0.9726530612244896 2.317108644920705 0.0204978142125638 1.0 0.0856933335616498 4 Q9BUF5,P07437,P68371 3
4
+ EF-hand domain [IPR002048] 0.530961463799274 2.218680806632741 0.0265084477027324 1.0 0.0995758100683796 37 Q02818,Q9Y680,Q9BRK5,P80303,P30626,P60660,Q6NUK1,Q14257,Q9NWM8,O43852 10
5
+ ERAP1-like C-terminal domain [IPR024571] 0.944639847254494 2.208493834385211 0.0272098671403557 1.0 0.100560601985746 4 Q9UIQ6,P55786 2
6
+ TRAM/LAG1/CLN8 homology domain [IPR006634] 0.9677814029363774 2.141800408539122 0.0322095465498275 1.0 0.1130707386926124 2 Q96G23 1
7
+ Isopropylmalate dehydrogenase-like domain [IPR024084] 0.8873152080167173 2.10981464482015 0.0348743245356633 1.0 0.1189978458648424 5 P48735 1
8
+ Aminopeptidase N-like , N-terminal domain [IPR045357] 0.8487956553260017 2.0476699020294555 0.0405923549015689 1.0 0.1306919303492682 6 Q9UIQ6,P55786 2
9
+ Peptidase M1, membrane alanine aminopeptidase [IPR014782] 0.8487956553260017 2.0476699020294555 0.0405923549015689 1.0 0.1306919303492682 6 Q9UIQ6,P55786 2
10
+ 3-hydroxyacyl-CoA dehydrogenase, NAD binding [IPR006176] 0.9396411092985296 2.0245803127813957 0.04291047749655 1.0 0.1363585838365804 2 Q16836 1
11
+ 3-hydroxyacyl-CoA dehydrogenase, C-terminal [IPR006108] 0.9396411092985296 2.0245803127813957 0.04291047749655 1.0 0.1363585838365804 2 Q16836 1
12
+ Prolyl 4-hydroxylase alpha-subunit, N-terminal [IPR013547] 0.9282218597063596 1.9767220324643264 0.0480730589506812 1.0 0.1458105608724801 2 O15460 1
13
+ MD-2-related lipid-recognition domain [IPR003172] 0.921288743882542 1.9475874080892863 0.0514643516468977 1.0 0.1519061869416486 2 P17900 1
14
+ L27 domain, C-terminal [IPR014775] 0.9102773246329496 1.901198589597285 0.0572760057708205 1.0 0.1601909766371808 2 Q14168 1
15
+ L27 domain [IPR004172] 0.9102773246329496 1.901198589597285 0.0572760057708205 1.0 0.1601909766371808 2 Q14168 1
16
+ Post-SET domain [IPR003616] 0.9041598694942864 1.8753676346288648 0.0607421645252332 1.0 0.1659149542919129 2 Q03164 1
17
+ RNA recognition motif domain [IPR000504] 0.378074170879189 1.8015209851561067 0.0716208027380918 1.0 0.1818639090312515 103 Q13242,Q14011,Q9UHX1,Q8WXF1,Q99729,Q92804,Q76FK4,Q16630,Q01844,P09651,Q8IY67,Q9BWF3,P31483,P33240,P98175,Q86V81,Q9NW64,Q9P2N5,P51991,P62995,P84103,P52597,P38159,Q96I25,P31943,Q01085,O60506,P23246,P52756,Q9Y5S9,P55795,Q07955,P31942,Q15233,Q13151,Q14103,O43390,Q15056,P26368,P22626,P35637,Q12849,O75494,Q96EP5,O14979,Q96PK6 46
18
+ Peptidase M16, C-terminal [IPR007863] 0.7370053953010196 1.7846845193587506 0.0743125033406748 1.0 0.1865447429750502 7 O43847,P22695,P31930 3
19
+ Peptidase M16, N-terminal [IPR011765] 0.7370053953010196 1.7846845193587506 0.0743125033406748 1.0 0.1865447429750502 7 O43847,P22695,P31930 3
20
+ Cytochrome b5-like heme/steroid binding domain [IPR001199] 0.7235262421569126 1.7248398151995277 0.0845563442326717 1.0 0.2016696322859492 7 Q8WUJ1,O43169 2
21
+ CARG-binding factor, N-terminal [IPR012956] 0.8584828711256134 1.6813127852766698 0.0927021757953812 1.0 0.2138827848523954 2 Q99729 1
22
+ Fzo/mitofusin HR2 domain [IPR006884] 0.8552202283849897 1.6673827907161785 0.0954383136064214 1.0 0.2183859017903441 2 Q8IWA4 1
23
+ Polyketide synthase, enoylreductase domain [IPR020843] 0.7454167904723265 1.6177321585524065 0.1057203323735573 1.0 0.2327117226120647 6 Q8N4Q0,Q8WWV3 2
24
+ EB1, C-terminal [IPR004953] 0.8417618270799367 1.6098450380566791 0.1074316901858076 1.0 0.2346000861157806 2 Q15555 1
25
+ Chromo domain [IPR023780] 0.7820704257969376 1.555665654831928 0.119787617623607 1.0 0.2544447821921686 4 Q13185,P83916 2
26
+ FAD linked oxidase, N-terminal [IPR006094] 0.8201468189233188 1.5172299880830096 0.1292086275019155 1.0 0.2662884459950443 2 Q15392 1
27
+ FAD-binding domain, PCMH-type [IPR016166] 0.8201468189233188 1.5172299880830096 0.1292086275019155 1.0 0.2662884459950443 2 Q15392 1
28
+ NECAP, PHear domain [IPR012466] 0.816884176182707 1.5032344200080852 0.1327786045219285 1.0 0.2708535726750658 2 Q9NVZ3 1
29
+ Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337] 0.8058727569331184 1.455980892087177 0.1453979018861548 1.0 0.2848490006824648 2 O60506 1
30
+ RNA recognition motif domain, eukaryote [IPR003954] 0.5554846707895763 1.4066507766796772 0.1595309684809702 1.0 0.3002327704783304 12 P31483,Q14011,Q9UHX1,Q01085 4
31
+ Alcohol dehydrogenase, N-terminal [IPR013154] 0.7164092991088973 1.4034084501435753 0.1604950746135216 1.0 0.3008769557332771 5 Q8N4Q0 1
32
+ Reticulon [IPR003388] 0.7915986949428915 1.3947091429242993 0.1631035666761513 1.0 0.3025521889093968 2 O95197 1
33
+ Chromo domain subgroup [IPR017984] 0.8494492044063684 1.37645728993164 0.1686801015807824 1.0 0.3091062861467837 3 Q13185,P83916 2
34
+ Chromo shadow domain [IPR008251] 0.8494492044063684 1.37645728993164 0.1686801015807824 1.0 0.3091062861467837 3 Q13185,P83916 2
35
+ Guanylate kinase/L-type calcium channel beta subunit [IPR008145] 0.7374326042682576 1.3712656051135812 0.1702921735319846 1.0 0.3115411727095127 4 Q14168 1
36
+ Guanylate kinase-like domain [IPR008144] 0.7374326042682576 1.3712656051135812 0.1702921735319846 1.0 0.3115411727095127 4 Q14168 1
37
+ OCRE domain [IPR041591] 0.7577487765089719 1.2496015075705116 0.2114451521464175 1.0 0.3571181947542029 2 P98175 1
38
+ Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862] 0.8097955485409687 1.22265608465917 0.2214596203344563 1.0 0.3680950152044365 3 O15460 1
39
+ Marvel domain [IPR008253] 0.744698205546495 1.1938524607785177 0.2325356862663188 1.0 0.3786605213089629 2 O43760 1
40
+ GOLD domain [IPR009038] 0.6922448979591808 1.1838762639886198 0.2364620473344807 1.0 0.3806588887910125 4 Q9Y3B3,Q9H3P7,P49755 3
41
+ Far upstream element-binding protein, C-terminal [IPR015096] 0.7373572593800987 1.1625723546090996 0.245003052663109 1.0 0.3884367071421606 2 Q96AE4 1
42
+ 14-3-3 domain [IPR023410] 0.6347601898743878 1.1426666095990483 0.2531770382339848 1.0 0.3982377017714826 6 P61981,P27348,Q04917 3
43
+ Dynamin-type guanine nucleotide-binding (G) domain [IPR030381] 0.6328978718167115 1.1346218405662776 0.2565337980958255 1.0 0.4003675103000144 6 Q8IWA4 1
44
+ Dynamin, N-terminal [IPR045063] 0.6328978718167115 1.1346218405662776 0.2565337980958255 1.0 0.4003675103000144 6 Q8IWA4 1
45
+ Target SNARE coiled-coil homology domain [IPR000727] 0.667224418404735 1.0803661544198857 0.2799791612906099 1.0 0.423051500752052 4 Q9UNK0,O95721 2
46
+ SET domain [IPR001214] 0.7674006701798807 1.0592500979631432 0.2894858948065049 1.0 0.4292511683610952 3 Q03164 1
47
+ Zinc finger C2H2 AKAP95-type [IPR034736] 0.7120717781402975 1.055431335949665 0.29122809764737 1.0 0.4306728895269446 2 Q9ULX6 1
48
+ Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain [IPR014038] 0.7096247960848292 1.0451239726075388 0.2959656757463005 1.0 0.4332585524983041 2 P24534 1
49
+ Elongation factor 1 beta central acidic region, eukaryote [IPR018940] 0.7096247960848292 1.0451239726075388 0.2959656757463005 1.0 0.4332585524983041 2 P24534 1
50
+ Fragile X-related 1 protein, C-terminal region 1 [IPR032172] 0.7092169657422516 1.0434072988357477 0.2967596945501372 1.0 0.4336194606475783 2 P51114 1
51
+ Zinc finger, CHHC-type [IPR012996] 0.7572419420644685 1.020407065811077 0.3075354442037334 1.0 0.4434560274124655 3 P52597,P31943 2
52
+ LEM domain [IPR003887] 0.6238487538961888 1.0108099325686115 0.3121074082845871 1.0 0.446534932217181 5 Q9Y2U8,Q86XL3 2
53
+ NOPS [IPR012975] 0.754385964912281 1.0095163671466845 0.3127270561959967 1.0 0.4471305569408302 3 Q8WXF1,P23246 2
54
+ Zinc finger, RanBP2-type [IPR001876] 0.5094374431513398 0.9557446505302828 0.3392012581445858 1.0 0.4729889452504401 9 P35637,Q92804 2
55
+ Ancestral coatomer element 1, Sec16/Sec31 [IPR024298] 0.6859706362153364 0.9462158300471588 0.3440385136618098 1.0 0.4779804953973415 2 O15027 1
56
+ CSN8/PSMD8/EIF3K [IPR033464] 0.7265086603774438 0.9040418891982872 0.3659731898995677 1.0 0.496774718882191 3 Q99627 1
57
+ U2A'/phosphoprotein 32 family A, C-terminal [IPR003603] 0.6725122349102785 0.8906525976750244 0.3731155723858286 1.0 0.5046009493705025 2 Q92688 1
58
+ Fragile X-related 1 protein, C-terminal core [IPR022034] 0.7095063239494073 0.8406258604223189 0.4005575665772056 1.0 0.5264949724466678 3 P51114,Q06787 2
59
+ Synaptic functional regulator FMRP, KH0 domain [IPR040472] 0.7095063239494073 0.8406258604223189 0.4005575665772056 1.0 0.5264949724466678 3 P51114,Q06787 2
60
+ Fxr1, tudor domain [IPR041560] 0.7095063239494073 0.8406258604223189 0.4005575665772056 1.0 0.5264949724466678 3 P51114,Q06787 2
61
+ Agenet-like domain [IPR008395] 0.7095063239494073 0.8406258604223189 0.4005575665772056 1.0 0.5264949724466678 3 P51114,Q06787 2
62
+ ABC transporter type 1, transmembrane domain [IPR011527] 0.5640427011505411 0.8392374562165842 0.4013360722994201 1.0 0.5270467462015089 6 P08183 1
63
+ FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179] 0.4692481916726755 0.7559471567258431 0.4496808790472157 1.0 0.5670001450830433 9 Q9Y680,Q00688,P26885,Q9NWM8,Q96AY3 5
64
+ Metaxin, glutathione S-transferase domain [IPR033468] 0.6743892552988815 0.7126305448747322 0.4760744054612253 1.0 0.5845193356496229 3 Q13505 1
65
+ Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain [IPR019564] 0.6743892552988815 0.7126305448747322 0.4760744054612253 1.0 0.5845193356496229 3 Q13505 1
66
+ SH3 domain [IPR001452] 0.3786273874628865 0.6901578266901605 0.4900949413376743 1.0 0.5927362915591093 22 Q9UQB8,Q14168,Q9NZW5 3
67
+ EF hand associated, type-1 [IPR013566] 0.6211256117455195 0.6853804047367859 0.4931039059249764 1.0 0.5935060148489454 2 Q8IXI1 1
68
+ EF hand associated, type-2 [IPR013567] 0.6211256117455195 0.6853804047367859 0.4931039059249764 1.0 0.5935060148489454 2 Q8IXI1 1
69
+ MIRO domain [IPR020860] 0.6211256117455195 0.6853804047367859 0.4931039059249764 1.0 0.5935060148489454 2 Q8IXI1 1
70
+ Peptidase C2, calpain, catalytic domain [IPR001300] 0.619086460032632 0.6775200537153125 0.4980760508708892 1.0 0.5958825431747543 2 P17655 1
71
+ Peptidase C2, calpain, domain III [IPR022683] 0.619086460032632 0.6775200537153125 0.4980760508708892 1.0 0.5958825431747543 2 P17655 1
72
+ Peptidase C2, calpain, large subunit, domain III [IPR022682] 0.619086460032632 0.6775200537153125 0.4980760508708892 1.0 0.5958825431747543 2 P17655 1
73
+ Calpain subdomain III [IPR033883] 0.619086460032632 0.6775200537153125 0.4980760508708892 1.0 0.5958825431747543 2 P17655 1
74
+ Tyrosine-protein kinase, catalytic domain [IPR020635] 0.6141924959217027 0.6587622194579056 0.5100484716271583 1.0 0.6039830851416914 2 Q15375 1
75
+ UBX domain [IPR001012] 0.6541436803673615 0.6411781449286058 0.5214069473390364 1.0 0.6123192273976081 3 Q9UNZ2 1
76
+ Death domain [IPR000488] 0.6483068135454905 0.6209607671148147 0.534625437143172 1.0 0.6213749134660863 3 Q96FV9,Q12955 2
77
+ Ricin B, lectin domain [IPR000772] 0.6393308853529265 0.5902397891383343 0.5550298999112839 1.0 0.6367370341206156 3 Q9UMS4,Q10472 2
78
+ Prolyl 4-hydroxylase, alpha subunit [IPR006620] 0.4679617290939928 0.5703474394750994 0.5684420710832585 1.0 0.646590998859427 7 O15460 1
79
+ Oxoglutarate/iron-dependent dioxygenase [IPR005123] 0.4679617290939928 0.5703474394750994 0.5684420710832585 1.0 0.646590998859427 7 O15460 1
80
+ Legume-like lectin [IPR005052] 0.5840130505709693 0.5468256479520451 0.5844985207016271 1.0 0.6593845243675468 2 Q12907 1
81
+ B-box-type zinc finger [IPR000315] 0.5318367346938727 0.5449339288798186 0.5857989600253113 1.0 0.6593845243675468 4 Q13263,Q12899,Q9UPN9 3
82
+ Serine hydroxymethyltransferase-like domain [IPR039429] 0.5469004893964198 0.4199294669115569 0.6745369806684534 1.0 0.737596628786638 2 P34897 1
83
+ DnaJ domain [IPR001623] 0.3604006109650538 0.4078942192512672 0.6833513369557811 1.0 0.7453817410544458 14 Q99543,Q8WXX5,O75937,Q13217,Q8IXB1 5
84
+ Acyl-CoA oxidase/dehydrogenase, central domain [IPR006091] 0.4180154910765672 0.3677531167506733 0.7130573302364904 1.0 0.7747100144219577 7 P16219 1
85
+ Zinc finger, CCCH-type [IPR000571] 0.3724302655116486 0.3655178865047098 0.7147248576069178 1.0 0.7761382527790678 11 Q9NW64,Q9P2N5,Q8IWR0,Q96GM8 4
86
+ Glucosamine/galactosamine-6-phosphate isomerase [IPR006148] 0.5289559543230089 0.3637673959912566 0.7160317112522443 1.0 0.7771736095970806 2 O95336 1
87
+ Aldehyde dehydrogenase domain [IPR015590] 0.3824266676754498 0.3521192955933475 0.7247487981414227 1.0 0.7846984771605064 9 O94788,P51648,P30837 3
88
+ Ribosomal protein S10 domain [IPR027486] 0.5224306688417732 0.3442930217434618 0.7306259317158899 1.0 0.7895068421834113 2 P60866 1
89
+ PITH domain [IPR010400] 0.5154975530179531 0.3241863244071596 0.7457969750202127 1.0 0.8027447616590542 2 Q9GZP4 1
90
+ Alcohol dehydrogenase-like, C-terminal [IPR013149] 0.4310577740559467 0.3202428681169919 0.7487842288489137 1.0 0.805171892048294 6 Q8N4Q0 1
91
+ GTPase effector domain [IPR020850] 0.5097879282218654 0.3080940396808397 0.7580107764364625 1.0 0.8123127180232852 2 O00429 1
92
+ Dynamin GTPase effector [IPR003130] 0.5097879282218654 0.3080940396808397 0.7580107764364625 1.0 0.8123127180232852 2 O00429 1
93
+ Dynamin stalk domain [IPR000375] 0.5097879282218654 0.3080940396808397 0.7580107764364625 1.0 0.8123127180232852 2 O00429 1
94
+ Chromo/chromo shadow domain [IPR000953] 0.4266589186549413 0.305547316920649 0.7599493380829627 1.0 0.8139934702603191 6 Q13185,P83916 2
95
+ FCP1 homology domain [IPR004274] 0.5081566068515619 0.3035752121107942 0.7614515387167815 1.0 0.8148087268312421 2 Q05D32 1
96
+ Proteasome component (PCI) domain [IPR000717] 0.3297196784467691 0.2992611587260076 0.7647407881526767 1.0 0.8179304441380039 17 P60228,Q99627,P48556,Q9BT78,Q7L2H7 5
97
+ AP complex, mu/sigma subunit [IPR022775] 0.437174282004364 0.2939874609439734 0.7687674849348043 1.0 0.8206798604572533 5 P61923 1
98
+ PDZ domain [IPR001478] 0.3404866415315078 0.2887064698968115 0.7728060111825465 1.0 0.8241515124104849 13 Q14168,Q9NZW5 2
99
+ Peroxiredoxin, C-terminal [IPR019479] 0.4497959183673415 0.2755580446681805 0.7828875378779225 1.0 0.8332863968023 4 P32119,P30041,P30048 3
100
+ Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant [IPR000866] 0.4497959183673415 0.2755580446681805 0.7828875378779225 1.0 0.8332863968023 4 P32119,P30041,P30048 3
101
+ B-box, C-terminal [IPR003649] 0.5316197470420256 0.2692939052029608 0.78770352195051 1.0 0.8375178319333667 3 Q13263,Q9UPN9 2
102
+ Ubiquitin system component CUE [IPR003892] 0.5314604047303941 0.2689013002981928 0.7880056363211168 1.0 0.8375178319333667 3 Q9Y679 1
103
+ PTBP1, RNA recognition motif 2-like [IPR021790] 0.5303957568339488 0.2662854603523814 0.7900193699443316 1.0 0.8388472209114367 3 Q8WVV9,P26599 2
104
+ CRIB domain [IPR000095] 0.4926590538336183 0.262450587753067 0.792974075683069 1.0 0.840097429815647 2 O96013 1
105
+ p21 activated kinase binding domain [IPR033923] 0.4926590538336183 0.262450587753067 0.792974075683069 1.0 0.840097429815647 2 O96013 1
106
+ ENTH domain [IPR013809] 0.492251223491031 0.2614133905523975 0.7937737317963602 1.0 0.840097429815647 2 Q13492 1
107
+ Proteasome activator PA28, C-terminal domain [IPR003186] 0.5273289556283682 0.2588222087647908 0.7957724214885944 1.0 0.8408955093000572 3 Q9UL46 1
108
+ Proteasome activator PA28, N-terminal domain [IPR003185] 0.5273289556283682 0.2588222087647908 0.7957724214885944 1.0 0.8408955093000572 3 Q9UL46 1
109
+ Syntaxin, N-terminal domain [IPR006011] 0.4816476345840199 0.235279865916175 0.8139915212136193 1.0 0.8568536884388458 2 Q86Y82 1
110
+ SH2 domain [IPR000980] 0.4127032459666241 0.2218356947274076 0.8244417912982387 1.0 0.8666097031858637 5 Q7KZ85 1
111
+ Dynamin, GTPase domain [IPR001401] 0.5099959200326435 0.2186946807741671 0.8268878928223689 1.0 0.8683507527776452 3 O00429,O60313 2
112
+ Glutathione S-transferase, N-terminal [IPR004045] 0.3948965323409548 0.2067602914739015 0.8361970688127103 1.0 0.8764525044419209 6 Q9H7Z7 1
113
+ 60S ribosomal protein L10P, insertion domain [IPR040637] 0.4624796084828763 0.1922142527944003 0.8475743819519233 1.0 0.8866869961523688 2 Q9UKD2 1
114
+ C-CAP/cofactor C-like domain [IPR017901] 0.4592169657422552 0.1854305609697427 0.8528913398614397 1.0 0.8914011674692519 2 O75695 1
115
+ CARP motif [IPR006599] 0.4592169657422552 0.1854305609697427 0.8528913398614397 1.0 0.8914011674692519 2 O75695 1
116
+ ABC transporter-like, ATP-binding domain [IPR003439] 0.3360751075974014 0.1711004517138927 0.8641447806939491 1.0 0.90187677871191 9 P08183 1
117
+ Staufen, C-terminal [IPR032478] 0.4506525285481258 0.1683888267852185 0.8662773975326201 1.0 0.9036736229479276 2 O95793 1
118
+ Dual specificity protein phosphatase domain [IPR020422] 0.4420880913539993 0.1524586526690709 0.8788251995421921 1.0 0.9156025498162766 2 Q99956 1
119
+ Dual specificity phosphatase, catalytic domain [IPR000340] 0.4420880913539993 0.1524586526690709 0.8788251995421921 1.0 0.9156025498162766 2 Q99956 1
120
+ Domain of unknown function DUF4749 [IPR031847] 0.4416802610114196 0.1517277973296535 0.8794016318981703 1.0 0.9156025498162766 2 Q96HC4 1
121
+ Immunoglobulin V-set domain [IPR013106] 0.4404567699836864 0.1495503341162671 0.8811193950062448 1.0 0.9164622617688024 2 Q9Y624 1
122
+ RING-type zinc-finger, LisH dimerisation motif [IPR027370] 0.4704202366381086 0.1408059974326015 0.8880232050074126 1.0 0.9228558732567582 3 Q9UPN9,O15344 2
123
+ HDGF-related, PWWP domain [IPR035496] 0.4638922888617001 0.1298505413594051 0.8966846751576705 1.0 0.9296603492087304 3 P51858,Q7Z4V5 2
124
+ Nucleotidyl transferase domain [IPR005835] 0.4143556280587285 0.1084386695874087 0.9136477280774726 1.0 0.9450194515721364 2 Q96IJ6 1
125
+ SCP2 sterol-binding domain [IPR003033] 0.4475724194206439 0.1048161421424636 0.9165217010295909 1.0 0.9471011374831156 3 P22307,Q6YN16 2
126
+ Exportin-2, central domain [IPR013713] 0.4447164422684638 0.1007782577984135 0.9197264867191666 1.0 0.9499664369635732 3 O15397,P55060 2
127
+ Lamin tail domain [IPR001322] 0.4283965728274241 0.0796273941586637 0.9365336070019998 1.0 0.965512143364931 3 P20700,Q03252 2
128
+ Tyrosine-specific protein phosphatases domain [IPR000387] 0.4263565891472868 0.0772098447773083 0.938456610027922 1.0 0.9670412771562326 3 P51452,Q99956 2
129
+ Heat shock chaperonin-binding [IPR006636] 0.4247246022031825 0.075311342209227 0.9399669973345108 1.0 0.96814399397592 3 Q9NRR5,P54727 2
130
+ PWI domain [IPR002483] 0.3470804409963287 0.07215289031026 0.9424802354904316 1.0 0.9702781076046156 5 P49756,Q9P2N5,Q5T8P6,O43395 4
131
+ DDE superfamily endonuclease domain [IPR004875] 0.362561174551386 0.0548991693614683 0.9562187936362204 1.0 0.9804588643794442 2 P07199 1
132
+ HTH CenpB-type DNA-binding domain [IPR006600] 0.362561174551386 0.0548991693614683 0.9562187936362204 1.0 0.9804588643794442 2 P07199 1
133
+ ERM family, FERM domain C-lobe [IPR041789] 0.4010607915136749 0.0512165369805654 0.9591529745335116 1.0 0.9821003237237764 3 P26038,P35241 2
134
+ Intermediate filament head, DNA-binding domain [IPR006821] 0.3352851606690825 0.0438251327678045 0.965043793275437 1.0 0.985662471626886 4 P08670 1
135
+ PWWP domain [IPR000313] 0.3240517958286456 0.041931532276672 0.9665532793744284 1.0 0.98638039762219 6 O96028 1
136
+ Thioesterase domain [IPR006683] 0.3409461663947814 0.0418179587821896 0.9666438184974168 1.0 0.98638039762219 2 O00154 1
137
+ Ubiquitin-associated domain [IPR015940] 0.2936125829290161 0.0408246072998019 0.9674357219203352 1.0 0.9867305902146648 9 Q13501 1
138
+ Endonuclease/exonuclease/phosphatase [IPR005135] 0.3269387755101985 0.0345088477381227 0.972471387077021 1.0 0.9900298982325784 4 Q6L8Q7,O95551,Q9ULM6 3
139
+ Brix domain [IPR007109] 0.343533251733981 0.0157720472556526 0.987416248721656 1.0 1.0 3 Q9NQ55,Q9H7B2 2
140
+ Sterile alpha motif domain [IPR001660] 0.2991836734693837 0.0100717080758427 0.9919640754853656 1.0 1.0 4 Q15375,Q8IXK0,Q9Y3Z3 3
141
+ Zinc finger, C3HC4 RING-type [IPR018957] 0.313749490004077 0.0070003422550446 0.9944145806131202 1.0 1.0 3 P38398,Q5VTR2 2
142
+ Flavoprotein pyridine nucleotide cytochrome reductase [IPR001709] 0.3133414932680503 0.0069124818985344 0.9944846813388976 1.0 1.0 3 P16435,Q9UHQ9 2
143
+ Oxidoreductase FAD/NAD(P)-binding [IPR001433] 0.3133414932680503 0.0069124818985344 0.9944846813388976 1.0 1.0 3 P16435,Q9UHQ9 2
144
+ FAD-binding domain, ferredoxin reductase-type [IPR017927] 0.3133414932680503 0.0069124818985344 0.9944846813388976 1.0 1.0 3 P16435,Q9UHQ9 2
145
+ F-box domain [IPR001810] 0.2986536107711117 0.0042174984773395 0.9966349330556296 1.0 1.0 3 Q14241,Q9Y2K7 2
interpro_domain/selections.json ADDED
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interpro_family/advanced/idx2term.json ADDED
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1
+ {"0": "Proteasome, subunit alpha/beta [IPR001353]", "1": "Proteasome B-type subunit [IPR023333]"}
interpro_family/advanced/plot_0.png ADDED

Git LFS Details

  • SHA256: af0f6d9b5dd6d6ec5f3204e3c77ae82da66d7e897b96df35c2147b4bd56c36d6
  • Pointer size: 131 Bytes
  • Size of remote file: 189 kB
interpro_family/advanced/plot_1.png ADDED

Git LFS Details

  • SHA256: 8b5ea8654bc9b04a4f05c34fb0d80de7217ce7ea8a41afbc74c2f7d754d0c4fe
  • Pointer size: 131 Bytes
  • Size of remote file: 180 kB
interpro_family/basic/idx2term.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {"0": "Proteasome, subunit alpha/beta [IPR001353]", "1": "Proteasome B-type subunit [IPR023333]", "2": "Mitochondrial carrier protein [IPR002067]", "3": "Small GTPase [IPR001806]"}
interpro_family/basic/plot_0.png ADDED

Git LFS Details

  • SHA256: f407e436ea853ebf121cf397c5d8efc0cca4e801b9cb835194d10903e34630a3
  • Pointer size: 131 Bytes
  • Size of remote file: 145 kB
interpro_family/basic/plot_1.png ADDED

Git LFS Details

  • SHA256: 87c003336ffb7f1f530ae012e76cb17f38697ef7fe5003be9e1eb0fbcbf32797
  • Pointer size: 131 Bytes
  • Size of remote file: 135 kB
interpro_family/basic/plot_2.png ADDED

Git LFS Details

  • SHA256: d148c7110c8b5faf56e5f2172f491bb1010282beeffe7de7205dfeddb836679d
  • Pointer size: 131 Bytes
  • Size of remote file: 132 kB
interpro_family/basic/plot_3.png ADDED

Git LFS Details

  • SHA256: 975a7410997720c83e532e37fca31b371a3c8a65054a4ce8d03dda7654e33680
  • Pointer size: 131 Bytes
  • Size of remote file: 143 kB