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interpro_active_site/advanced/idx2term.json

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+{}

interpro_active_site/basic/idx2term.json

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+{}

interpro_active_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:16e7d2b8662dbd1ade8648bfd26d03cf712e1ad9e7c691ed44f5894ad133618a
+size 75042

interpro_active_site/df_merge.tsv

@@ -0,0 +1 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_active_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3120,
+    "annotations_size": 54,
+    "title": "Average number of proteins per term",
+    "value": 2.574074074074074
+}

interpro_active_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C390/C390_val_log2fc"}

interpro_active_site/result.tsv

@@ -0,0 +1,4 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Histidine acid phosphatase active site [IPR033379]	0.9900577293136624	1.7568362546023455	0.0789457235473234	0.988213033222178	0.2131534535777732	2	Q9NPH0	1
+Serine carboxypeptidase, serine active site [IPR018202]	0.9711260827718956	1.7225723835136637	0.0849658826709092	0.991727943210552	0.2184836982966236	3	Q9HB40,Q9H3G5	2
+Tyrosine-protein kinase, active site [IPR008266]	0.4287006022453715	0.0332753281212976	0.973455028168854	1.0	0.99182210417204	3	Q15375	1

interpro_active_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["ATP synthase, F0 complex, subunit A, active site [IPR023011]", "ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenosine/AMP deaminase active site [IPR006650]", "Adenylosuccinate synthase,  active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Coenzyme A transferase active site [IPR004164]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycoside hydrolase, family 2, active site [IPR023232]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]", "Uracil-DNA glycosylase, active site [IPR018085]"], "available_proteins": ["ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADA", "ADSS", "AKT2", "APEH", "ATP5A1", "ATP5B", "ATP6", "ATP6V1A", "ATP6V1B2", "AURKA", "BLMH", "CAMK2D", "CAMK2G", "CAPN1", "CAPN2", "CDK1", "CDK12", "CDK16", "CDK2", "CDK4", "CDK5", "CDK7", "CDK9", "CHEK2", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK1E", "CSNK2A2", "CTSA", "CTSC", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "EPHA7", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLUD1", "GSK3A", "GSK3B", "GSR", "GUSB", "HADHB", "HMGCL", "HMGCS1", "LDHA", "LDHB", "LONP1", "MAP2K1", "MAP2K2", "MAP3K7", "MAPK1", "MAPK3", "MARK2", "MDH1", "MDH2", "NEK9", "NME1", "NME2", "OXCT1", "PAK2", "PBK", "PGAM1", "PKM", "PKMYT1", "PKN2", "PLK1", "PREP", "PRKAA2", "PRKACA", "PRKCD", "PRPF4B", "PTK7", "PTPN1", "PTPN11", "PTPRF", "RIPK1", "RNASET2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SLK", "SND1", "SRPK1", "STK38", "SUCLG1", "TALDO1", "TIGAR", "TOP1", "TPI1", "TPP2", "TRIO", "TTK", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "UMPS", "UNG", "VRK1"], "leading_proteins": ["ACP6", "CPVL", "EPHA7", "SCPEP1"]}

interpro_binding_site/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "Beta tubulin, autoregulation binding site [IPR013838]", "1": "EF-Hand 1, calcium-binding site [IPR018247]"}

interpro_binding_site/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Beta tubulin, autoregulation binding site [IPR013838]", "1": "EF-Hand 1, calcium-binding site [IPR018247]"}

interpro_binding_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:211f67e9849b4767c14e62d2f5eba1e824f24dc2be33c2994ff4b4b6d4f4239b
+size 73158

interpro_binding_site/df_merge.tsv

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+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+Beta tubulin, autoregulation binding site [IPR013838]	5	6	2.217143950031643	0.0266132563012388	3.5533980582524274	5.54126213592233	0.5823511994709325	0.3808337519133083	1.5578062452886454	0.9632803779920796	1.1906256051626651	0.3058955364405814	1.0025096548661049e-05	1.0	1.0	0.1973959389561772	2.8311070051942505e-05
+EF-Hand 1, calcium-binding site [IPR018247]	16	35	2.0624093515123887	0.039168779739376	10.019417475728156	36.70631067961165	0.9532938980945532	0.3894555773109194	3.76037227687173	3.057484685571999	1.1082350706804749	0.3408841825650379	0.0036456478209502	0.0531691841805127	0.0402942577421927	0.2974580094294764	0.0047064147832106

interpro_binding_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3120,
+    "annotations_size": 31,
+    "title": "Average number of proteins per term",
+    "value": 4.645161290322581
+}

interpro_binding_site/paths.json

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+{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C390/C390_val_log2fc"}

interpro_binding_site/result.tsv

@@ -0,0 +1,5 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Beta tubulin, autoregulation binding site [IPR013838]	0.8188824662813031	2.217143950031643	0.0266132563012388	0.5666405718212666	0.1031263681673007	6	Q13885,Q9BVA1,P07437,Q9BUF5,P68371	5
+EF-Hand 1, calcium-binding site [IPR018247]	0.482097893902239	2.0624093515123887	0.039168779739376	0.7102254164194555	0.1317848851353061	35	Q6NUK1,P80303,Q9UBV8,Q15293,Q9NWM8,Q02818,O75746,Q9BRK5,Q9H4M9,Q9H223,P41208,Q96D71,O43852,Q14257,O95202,Q9BPX6	16
+Peptidase M16, zinc-binding site [IPR001431]	0.7181612291797281	1.6287438640597718	0.1033672527912181	0.9660333680332208	0.2670320697106469	5	Q10713	1
+Hexokinase, binding site [IPR019807]	0.7174470814625031	0.6573595275132368	0.5109497688022031	0.9999999997656	0.6570080745391734	2	P52789	1

interpro_binding_site/selections.json

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+{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Coenzyme A transferase binding site [IPR004163]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]", "Ureohydrolase, manganese-binding site [IPR020855]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "AKT2", "APEX1", "ARG2", "AURKA", "BPNT1", "CALU", "CAMK2D", "CAMK2G", "CAPN1", "CAPN2", "CDK1", "CDK12", "CDK16", "CDK2", "CDK4", "CDK5", "CDK7", "CDK9", "CETN2", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK1E", "CSNK2A2", "CYB5B", "DBT", "DLAT", "DLST", "DST", "EHD1", "EHD4", "EIF2AK2", "EPHA7", "EPS15", "EPS15L1", "FKBP10", "FKBP14", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3A", "GSK3B", "HK1", "HK2", "HMBS", "IDE", "ILKAP", "IQGAP1", "IQGAP2", "IQGAP3", "LETM1", "MACF1", "MAP2K1", "MAP2K2", "MAP3K7", "MAPK1", "MAPK14", "MAPK3", "MARK2", "MCCC1", "METAP2", "MICU1", "MYH10", "MYH14", "MYH9", "MYO1B", "MYO1C", "MYO1D", "NFS1", "NRDC", "NUCB1", "NUCB2", "OXCT1", "OXSR1", "PA2G4", "PAK2", "PAK4", "PC", "PCCA", "PDCD6", "PDHX", "PEF1", "PGD", "PKMYT1", "PKN2", "PLCG1", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1F", "PPM1G", "PRKAA2", "PRKACA", "PRKCD", "PRKCSH", "PSAT1", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "S100A11", "SDF4", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "STK26", "STK38", "STK4", "TKT", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "UBE3C", "UQCRC2", "VRK1"], "leading_proteins": ["CALU", "CETN2", "EHD1", "EHD4", "FKBP14", "HK2", "LETM1", "MICU1", "NUCB1", "NUCB2", "PEF1", "PMPCA", "RCN1", "RCN2", "REPS1", "SDF4", "SLC25A12", "SLC25A24", "TUBB", "TUBB2A", "TUBB2B", "TUBB4B", "TUBB6"]}

interpro_conserved_site/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "Intermediate filament protein, conserved site [IPR018039]", "1": "Syntaxin/epimorphin, conserved site [IPR006012]", "2": "Tubulin, conserved site [IPR017975]"}

interpro_conserved_site/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Intermediate filament protein, conserved site [IPR018039]", "1": "Syntaxin/epimorphin, conserved site [IPR006012]", "2": "Tubulin, conserved site [IPR017975]", "3": "14-3-3 protein, conserved site [IPR023409]"}

interpro_conserved_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:5357168823c234223683a7c8cb7cd876c5afa6b1f4a3757e220e96d57426d31a
+size 91068

interpro_conserved_site/df_merge.tsv

@@ -0,0 +1,4 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+Intermediate filament protein, conserved site [IPR018039]	7	8	2.539423265749998	0.0111035399638976	4.060679611650485	7.546116504854369	0.7869831563787604	0.2926647109331939	1.9153715257926656	0.8924219614624045	1.3691577499316503	0.3120813432784052	0.1557086547662877	1.0	1.0	0.3559534457378639	0.0097510399506001
+Syntaxin/epimorphin, conserved site [IPR006012]	5	7	2.1265644208842	0.033456291328977	2.592233009708738	5.847087378640777	0.9961908981999794	0.2839139128702306	1.4759357288864456	1.4239341993278547	1.138258151200134	0.2914162845337057	0.0127797815125809	0.0595353304203936	0.0066572828402184	0.0033170374819039	0.0027630263410089
+Tubulin, conserved site [IPR017975]	5	7	2.0895229346523223	0.0366606756361753	3.6140776699029127	5.883495145631068	0.537603280896448	0.3771225437200781	1.6631634011190108	1.117390952728082	1.2199662970774952	0.3090115161057067	0.000508394757649	1.0	1.0	0.3559534457378639	0.0013369974246366

interpro_conserved_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3120,
+    "annotations_size": 274,
+    "title": "Average number of proteins per term",
+    "value": 2.6605839416058394
+}

interpro_conserved_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C390/C390_val_log2fc"}

interpro_conserved_site/result.tsv

@@ -0,0 +1,32 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Intermediate filament protein, conserved site [IPR018039]	0.8206940874036005	2.539423265749998	0.0111035399638976	0.9530835335744045	0.1847406372560039	8	P20700,P48681,Q03252,Q16352,P07197,P08670,P07196	7
+Syntaxin/epimorphin, conserved site [IPR006012]	0.772314206387499	2.1265644208842	0.033456291328977	0.999910733082885	0.200900502486241	7	O15400,Q9P2W9,O60499,O43752,Q13190	5
+Tubulin, conserved site [IPR017975]	0.7644139892546106	2.0895229346523223	0.0366606756361753	0.9999640643778894	0.200900502486241	7	Q13885,Q9BVA1,P07437,Q9BUF5,P68371	5
+Tetraspanin, conserved site [IPR018503]	0.985246953175112	1.7369545789164331	0.0823951884768312	0.9999999999414324	0.3178829091749875	2	O60637	1
+Haem oxygenase conserved site [IPR018207]	0.9637588197562574	1.6480032080369134	0.0993520128786429	0.9999999999996468	0.3501861484121711	2	P30519	1
+Lysosome-associated membrane glycoprotein, conserved site [IPR018134]	0.9111610006414366	1.4297608656439509	0.1527856645457981	1.0	0.4228613341974614	2	P13473	1
+Glycoside hydrolase, family 29, conserved site [IPR018526]	0.9047466324567028	1.4031554358688756	0.1605704932530476	1.0	0.4328190112903487	2	P04066	1
+Guanylate kinase, conserved site [IPR020590]	0.6470316262682072	1.3003329514863775	0.1934868790114459	1.0	0.4776162599021277	5	Q14168,Q00013,Q9NZW5	3
+Heavy-metal-associated, conserved site [IPR017969]	0.8726747915330345	1.2704320630502226	0.2039307681959257	1.0	0.4857485196951406	2	P35670	1
+ABC transporter-like, conserved site [IPR017871]	0.5569203774798983	1.0666529256909665	0.2861285915877549	1.0	0.5850689111570512	7	O75027	1
+Short-chain dehydrogenase/reductase, conserved site [IPR020904]	0.4897841585870228	1.059660799449052	0.2892989427197867	1.0	0.5853595965441283	11	Q9Y394,Q8NBN7,Q53GQ0	3
+Proteasome beta-type subunit, conserved site [IPR016050]	0.5194304377633512	1.0073281489658956	0.3137771069729922	1.0	0.6097512575219849	8	P28074	1
+Polyprenyl synthetase, conserved site [IPR033749]	0.7896087235407556	0.9329898898351252	0.3508251884184408	1.0	0.6359649547981845	2	O95749	1
+DnaJ domain, conserved site [IPR018253]	0.4681837359336919	0.9301290194261876	0.3523042872590358	1.0	0.6359649547981845	11	Q9Y2G8,Q96KC8	2
+Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]	0.7639512508017945	0.8323456310676945	0.4052138810796455	1.0	0.6918050525257065	2	P04439	1
+Mini-chromosome maintenance, conserved site [IPR018525]	0.5255185569075023	0.8265316911399233	0.4085025484606701	1.0	0.6918050525257065	6	Q14566	1
+Aldehyde dehydrogenase, cysteine active site [IPR016160]	0.5024325576522944	0.7904179727767047	0.4292837093694726	1.0	0.6918050525257065	7	P51648	1
+Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]	0.7148813341885802	0.648053493256476	0.5169503523137564	1.0	0.7578416431898952	2	Q8N4Q0	1
+Thioredoxin, conserved site [IPR017937]	0.4266551344638164	0.6203691127130389	0.5350148027782946	1.0	0.7578416431898952	10	Q9H3N1,Q9H1E5,O43396,P07237	4
+Ubiquitin interacting motif [IPR003903]	0.4962402201446313	0.6082227466882916	0.5430397501234105	1.0	0.7578416431898952	5	Q8IZ07	1
+14-3-3 protein, conserved site [IPR023409]	0.4457289659601848	0.4561499034339971	0.6482821868260846	1.0	0.8252432377230629	6	P62258,Q04917,P31946,P61981,P63104	5
+Aldehyde dehydrogenase, glutamic acid active site [IPR029510]	0.4305827642097777	0.4399371006240634	0.6599826640677797	1.0	0.8252432377230629	7	P51648	1
+Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]	0.6289288005131448	0.3661449829219831	0.7142568930227418	1.0	0.8435620202078933	2	Q9H3P7	1
+HMG box A DNA-binding domain, conserved site [IPR017967]	0.5723452037215345	0.2804682819180716	0.7791182566736246	1.0	0.8969680770108114	3	O15347,P09429	2
+Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]	0.5540583894770699	0.2351465793245906	0.8140949669977326	1.0	0.9179507035283077	3	Q16539,P27361	2
+Cyclic nucleotide-binding, conserved site [IPR018488]	0.5311096856959532	0.1436931392035492	0.8857427890965717	1.0	0.9517393106371004	2	P13861	1
+Dynamin, GTPase region, conserved site [IPR019762]	0.4906991661321282	0.0882429420638139	0.9296835875838516	1.0	0.9654606633747382	2	P50570	1
+AMP-binding, conserved site [IPR020845]	0.3428571428571468	0.0650037313980638	0.9481710293144564	1.0	0.9766874512487258	5	O95573,Q6P1M0,P33121,O60488	4
+Histidine triad, conserved site [IPR019808]	0.4544579858883832	0.0551313724907688	0.9560338025112088	1.0	0.9774375443584744	2	Q9BX68	1
+Actin, conserved site [IPR004001]	0.438241899262121	0.042053832785386	0.9664557836859506	1.0	0.9807736471479648	3	P61163,P42025	2
+Heat shock protein Hsp90, conserved site [IPR019805]	0.408084696823869	0.0174706566868775	0.986061141844707	1.0	0.9969769478429878	3	P07900,P14625	2

interpro_conserved_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Bax inhibitor 1, conserved site [IPR006213]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAMSAP, spectrin and Ca2+/calmodulin-binding region [IPR031372]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific,  conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family A, conserved site [IPR019760]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "Dihydroorotate dehydrogenase, conserved site [IPR001295]", "DnaJ domain, conserved site [IPR018253]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Ependymin, conserved site [IPR018224]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "Ferritin, conserved site [IPR014034]", "Fibrillarin, conserved site [IPR020813]", "Fork head domain conserved site 2 [IPR030456]", "Fork head domain conserved site1 [IPR018122]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glutathione peroxidase conserved site [IPR029760]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 2, conserved site [IPR023230]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Golgin subfamily A member 2, C-terminal binding motif [IPR043937]", "Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Heavy-metal-associated, conserved site [IPR017969]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site [IPR023076]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Integrin alpha chain, C-terminal cytoplasmic region, conserved site [IPR018184]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M22, conserved site [IPR017860]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosyl pyrophosphate synthetase, conserved site [IPR000842]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RIO kinase, conserved site [IPR018935]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P,  conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "Ribosome-binding factor A, conserved site [IPR020053]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Transcription factor TFIIB, conserved site [IPR023486]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "Tyrosine-protein kinase, receptor class V, conserved site [IPR001426]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPA, conserved site [IPR022658]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]", "Zinc finger, XPA-type, conserved site [IPR022652]", "tRNA-dihydrouridine synthase, conserved site [IPR018517]"], "available_proteins": ["AAAS", "AAMP", "ABCB1", "ABCB7", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR1B", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK4", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANKRD13A", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1M1", "AP2M1", "AP2S1", "AP3M1", "APEX1", "ARHGEF7", "ARIH2", "ATAD1", "ATAD2", "ATP5C1", "ATP5O", "ATP7A", "ATP7B", "BAG6", "BAZ1A", "BAZ1B", "BCS1L", "BOP1", "BPNT1", "BRCA1", "BRD1", "BRD2", "BRD3", "BRD4", "BUD31", "CAD", "CALR", "CAMSAP3", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CBR1", "CBX1", "CBX3", "CBX5", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDH2", "CDK5RAP1", "CDKAL1", "CETN2", "CHAF1B", "CHD1", "CHD1L", "CHD4", "CLGN", "CMPK1", "CNDP2", "COLEC12", "COPA", "COPZ1", "CORO1C", "CPOX", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CYP51A1", "DCAF13", "DCAF7", "DCPS", "DCXR", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX55", "DDX6", "DHCR7", "DHFR", "DHODH", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX38", "DHX40", "DHX8", "DHX9", "DIDO1", "DIS3", "DLG1", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC16", "DNAJC2", "DNAJC21", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DRG1", "DRG2", "DSG2", "DST", "DTYMK", "DUS2", "DYNLL1", "DYNLL2", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EHHADH", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4E", "EIF4E2", "ENO1", "ENO2", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPRS", "EPS15", "ETFA", "ETFB", "EXO1", "EZR", "FARP2", "FBL", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FOXK1", "FOXK2", "FTL", "FUCA1", "FUCA2", "GAA", "GALK1", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GGPS1", "GLA", "GLB1", "GLO1", "GMPPA", "GNPDA1", "GNS", "GOLGA2", "GPI", "GPX8", "GRHPR", "GRWD1", "GSPT1", "GTF2B", "GTF3C2", "GUF1", "GUSB", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HGS", "HIBADH", "HINT2", "HLA-A", "HLA-B", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCR", "HMOX1", "HMOX2", "HSD17B10", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "ILVBL", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INTS12", "IQGAP1", "IQGAP2", "IQGAP3", "ITGAV", "IVD", "KDM2A", "KDM5A", "KDSR", "KIF11", "KIF14", "KIF1A", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "LAMP1", "LAMP2", "LARS", "LARS2", "LBR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK14", "MAPK3", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME1", "ME2", "MGST2", "MID1", "MIF", "MPI", "MPP1", "MPP2", "MPP6", "MPST", "MRC2", "MRPL13", "MRPL3", "MRPS11", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS8", "NDUFV1", "NEFL", "NEFM", "NES", "NF1", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NSD1", "NSD2", "NSF", "NUBP2", "NUDT1", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL11", "OSBPL8", "OSBPL9", "OSGEP", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PBRM1", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA6", "PEBP1", "PEPD", "PEX1", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHF3", "PHGDH", "PHIP", "PI4KA", "PIK3C2A", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PNP", "PNPLA6", "POLA1", "POLD1", "POLG", "POLR1B", "POLR1C", "POLR2B", "POLR2C", "POLR2E", "PPIB", "PPIC", "PPID", "PPIF", "PPIG", "PPIH", "PPIL1", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PRPS1", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PUS7", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "QDPR", "RACK1", "RAE1", "RANBP2", "RARS", "RASA1", "RBFA", "RCL1", "RDH13", "RDX", "RIDA", "RIOK2", "RNF2", "RNF20", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS24", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "RSF1", "RTCA", "S100A10", "S100A11", "SART1", "SBDS", "SCAF11", "SCAP", "SCD", "SCP2", "SDHB", "SEC61A1", "SERPINB1", "SERPINB6", "SERPINH1", "SLC1A5", "SLC27A4", "SLC2A1", "SLC2A8", "SLIT2", "SMARCA4", "SMS", "SMU1", "SNRNP40", "SNU13", "SORD", "SPATA5", "SPATA5L1", "SPTBN1", "SPTBN2", "SRCAP", "SRM", "STAM", "STMN1", "STRN", "STX10", "STX12", "STX18", "STX4", "STX5", "STX6", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SYNE1", "SYNE2", "TBL3", "TCP1", "TFB1M", "THOC6", "TK1", "TLN1", "TLN2", "TMBIM6", "TMX1", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRIM13", "TRIM21", "TRIM25", "TRIM28", "TRIM33", "TRIP13", "TRMT11", "TSFM", "TSPAN3", "TSPAN6", "TTF2", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUFM", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UBA5", "UHRF1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP24", "USP28", "USP33", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VARS2", "VAT1", "VCL", "VCP", "VIM", "VPS4A", "VPS4B", "WARS", "WARS2", "WDR1", "WDR12", "WDR18", "WDR3", "WDR36", "WDR41", "WDR5", "WDR61", "WDR7", "WDR77", "XPA", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2"], "leading_proteins": ["ABCB7", "ACBD3", "ACSL1", "ACSL3", "ACSL4", "ACTR1A", "ACTR1B", "ALDH3A2", "ANKRD13A", "ATP7B", "DHRS7", "DNAJC1", "DNAJC16", "DNM2", "FUCA1", "GGPS1", "HINT2", "HLA-A", "HMGB1", "HMGB3", "HMOX2", "HSD17B12", "HSP90AA1", "HSP90B1", "INA", "LAMP2", "LMNB1", "LMNB2", "MAPK14", "MAPK3", "MCM6", "MPP1", "MPP2", "MPP6", "NEFL", "NEFM", "NES", "P4HB", "PRKAR2A", "PSMB5", "RDH13", "SLC27A4", "STX10", "STX18", "STX5", "STX6", "STX7", "TMX1", "TMX4", "TSPAN3", "TUBB", "TUBB2A", "TUBB2B", "TUBB4B", "TUBB6", "TXNL1", "VIM", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAZ", "ZADH2"]}

interpro_domain/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "P-type ATPase, haloacid dehalogenase domain [IPR044492]", "1": "Intermediate filament, rod domain [IPR039008]", "2": "EF-hand domain [IPR002048]", "3": "Immunoglobulin-like domain [IPR007110]", "4": "GOLD domain [IPR009038]", "5": "Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]", "6": "Tubulin/FtsZ, GTPase domain [IPR003008]", "7": "Band 7 domain [IPR001107]"}

interpro_domain/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "P-type ATPase, haloacid dehalogenase domain [IPR044492]", "1": "Intermediate filament, rod domain [IPR039008]", "2": "EF-hand domain [IPR002048]", "3": "Immunoglobulin-like domain [IPR007110]", "4": "GOLD domain [IPR009038]", "5": "Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]", "6": "Tubulin/FtsZ, GTPase domain [IPR003008]", "7": "Band 7 domain [IPR001107]", "8": "Target SNARE coiled-coil homology domain [IPR000727]", "9": "SH3 domain [IPR001452]", "10": "PDZ domain [IPR001478]", "11": "Sterile alpha motif domain [IPR001660]", "12": "14-3-3 domain [IPR023410]", "13": "Protein kinase, C-terminal [IPR017892]", "14": "B-box-type zinc finger [IPR000315]"}