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019998f verified
Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
Protein localization 0.5684306694839097 4.106036836023768 4.025053220479968e-05 0.0546032728334663 0.0140373731064242 76 O43681,O60830,Q9NS69,Q99595,P21796,Q7L5D6,O75431,P46379,P09601,P05067,O00116,Q9NR77,Q5JRX3,Q9Y512,P12235,O43615,P50402,O43933,Q13011,O96008,Q8N4H5,O14734,O14925,P49069,Q13505,Q15388,P40855,Q13190,Q10713,P12236,Q96DA6,Q15067,Q9UJS0,P51648,P50542 35
Sphingolipid metabolism 0.7920358147880748 3.972116642553429 7.123682102849749e-05 0.0946004174935538 0.0141964807621079 28 Q16739,P17900,Q06136,P10619,Q9NRA0,P06865,Q96G23,O95470,O15269,O15121,Q13510,Q9NZD2,P51648,P07602,P06280,Q9NZJ7,P04062,P16278 18
Glycosphingolipid metabolism 0.8251094241511184 3.356549818413239 0.0007892150115078 0.6675911576606745 0.0846888416194973 16 Q16739,P17900,P10619,P06865,Q13510,Q9NZD2,P07602,P06280,Q9NZJ7,P04062,P16278 11
Transport of small molecules 0.5360510407817598 3.2565824064285382 0.0011276219329552 0.7927687908825166 0.097366076379044 155 P35613,Q8WTV0,Q9HD20,P21796,P25787,P28070,P45880,P09601,Q8N4V1,Q13555,P55011,P35670,P08195,P12235,O15118,P02786,P11166,P30519,O75027,P27105,Q15904,Q9UBV2,Q9Y487,Q9BUN8,P16615,P28072,Q8WWI5,P30825,P51798,Q93050,Q9C0H2,P61289,P10644,P63218,P53985,P61421,Q9UBX3,Q14997,P08183,P49721,Q9Y277,Q9NW15,Q8TB61,Q70HW3,P20618,O95202,P49720,Q9UL46,P12236,Q92530 50
Mitochondrial protein import 0.6234927055464833 3.2249879513630844 0.0012597797055136 0.8276969757865669 0.0976329271773047 36 O60830,Q10713,Q9NS69,Q99595,P21796,Q96DA6,Q13505,O75431,Q15388,O96008,Q9UJS0,Q8N4H5,P12236,Q5JRX3,Q9Y512,P12235,O43615,O14925 18
Slc mediated transmembrane transport 0.7265817596506239 3.105224648893469 0.0019013455683769 0.9296942584484164 0.1395987930466239 21 P35613,P11166,P12236,P53985,Q8TB61,Q70HW3,Q9UBX3,P55011,Q8WWI5,P30825,P12235 11
Glycosaminoglycan metabolism 0.7814752869068897 3.0613517433804835 0.0022034008047415 0.9539089020334006 0.1536872061307247 15 P15586,P06865,Q8NCH0,Q8TB61,P54802,P16278,Q7LGA3 7
Rac2 gtpase cycle 0.5948580949078578 2.9973571733586657 0.0027233143590137 0.9777231199960688 0.1703734879537538 36 P50402,Q7L576,O15173,Q8IZP0,P49257,Q14739,Q8TAA9,Q13505,P42167,P42166,Q15836,Q68EM7,Q9Y512,Q86XL3,P02786 15
Ion channel transport 0.6294366399037967 2.9124808412617655 0.0035857019594249 0.9933360552609828 0.1703734879537538 29 P27105,Q9NW15,Q9Y487,Q15904,Q9HD20,P61421,Q13555,P16615,P51798,Q93050,Q9C0H2 11
Cytoprotection by hmox1 0.4845853074503434 2.900449725304034 0.0037262760818848 0.994526648482261 0.1703734879537538 68 P13073,P30519,O75880,Q96I36,P61289,P49721,P25787,P28070,P00403,P09601,Q9UL46,Q14997,P20618,P28072,Q9P0S2,P49720,Q8TCT9,Q92530 18
Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins 0.4732295295192289 2.802139926256915 0.0050764850107276 0.9991746745125928 0.1703734879537538 69 P13073,P00846,Q9UDW1,P00403,Q86Y39,O96000,O95168,P24539,Q9P0J0,Q9P0S2,P03886,O14949,O43676,O75964 14
Abc family proteins mediated transport 0.5028036265118769 2.7704342229751044 0.0055981606066635 0.9996029209601934 0.1703734879537538 53 O75027,P61289,P49721,P25786,P25787,Q9UBV2,P28070,Q9BUN8,Q9UL46,Q14997,P20618,P28072,P49720,P08183,Q92530 15
G alpha i signalling events 0.6423947749816389 2.749801815082487 0.0059631318663506 0.99976205484649 0.1703734879537538 24 Q9NRV9,O43865,P10644,P30154,P63218,P04083,P30153,P05067,P07602,Q9NZJ7 10
Intra golgi and retrograde golgi to er traffic 0.4653924194484511 2.734813262899541 0.0062415673460127 0.9998390268001304 0.1703734879537538 99 Q13561,Q15363,Q86Y91,Q10472,Q9P2W9,P40616,P11717,O15260,O60499,Q15836,Q9Y3B3,O43752,O95249,Q9BVK6,Q9H0U4,O00461,Q5VZE5,O75935,Q13190,Q6NUQ1,P49755,Q9H2M9,Q9UJW0,Q02224,P20645,Q9H9E3 26
Abc transporter disorders 0.5184549254874674 2.6848086451026107 0.007257134251247 0.9999613365369732 0.1776088119384153 44 P61289,P49721,P25787,Q9UBV2,Q9BUN8,P28070,Q9UL46,Q14997,P20618,P28072,P49720,Q92530 12
Defective cftr causes cystic fibrosis 0.5204532919699189 2.6545055933489383 0.0079424722823211 0.9999852458109236 0.1910301523075517 43 P61289,P49721,P25787,Q9UBV2,Q9BUN8,P28070,Q9UL46,Q14997,P20618,P28072,P49720,Q92530 12
Gpcr ligand binding 0.8023964198202452 2.614192456823604 0.0089438640311843 0.9999963936708663 0.1986856812939868 10 Q9NRV9,P04083,P05067,P07602,P42892,Q9NZJ7 6
Metabolism of porphyrins 0.836049544795024 2.580422488194149 0.0098679506219698 0.999999018477938 0.1986856812939868 8 P30519,P09601 2
Regulation of pten stability and activity 0.5039139103377163 2.548945278731811 0.0108049252767827 0.9999997379925096 0.1986856812939868 44 P46934,P61289,P49721,P25787,P28070,P31751,Q9UL46,Q14997,P20618,P28072,P49720,Q92530 12
Phase i functionalization of compounds 0.7198968487927525 2.548521149975906 0.0108180726931887 0.9999997428056592 0.1986856812939868 13 P07099,P16435,Q16850,P30837,O43169 5
Sphingolipid de novo biosynthesis 0.7392341870254386 2.5410184963993268 0.0110530072070884 0.999999815347668 0.1986856812939868 12 Q06136,Q9NRA0,Q96G23,O95470,P51648,O15121 6
Biological oxidations 0.5164741871862906 2.528454989874569 0.011456577519709 0.99999989551058 0.1986856812939868 41 P07099,Q9NUJ1,P16435,Q16850,Q8TB61,P30837,O43169,Q99735,P78417,P21964 10
Rhog gtpase cycle 0.5422043434613155 2.510481415487384 0.0120566668235444 0.9999999552092173 0.1999991318833572 35 P50402,Q7L576,Q96JJ3,O15173,P42167,Q14739,Q8TAA9,P42166,O95202,Q15836,Q86XL3,Q13190,P02786 13
Regulation of hmox1 expression and activity 0.4834683193115734 2.506702387470859 0.0121863270323192 0.99999996270322 0.1999991318833572 47 P61289,P49721,P25786,P25787,P28070,P09601,Q9UL46,Q14997,P20618,P28072,P49720,P28074,Q8TCT9,Q92530,Q14145 15
Hedgehog ligand biogenesis 0.509614841848157 2.4662981269075286 0.0136517656519576 0.9999999952985836 0.2131640873312446 41 P61289,P49721,P25787,Q9UBV2,P28070,Q9UL46,Q14997,P20618,P28072,P49720,Q92530 11
Antigen processing cross presentation 0.4750682701475061 2.4636633395736607 0.0137525217633061 0.9999999959230204 0.2131640873312446 51 P10321,P61289,P49721,P25787,P28070,Q9UIQ6,P04439,Q03518,Q14997,Q15836,P28072,Q9UL46,P20618,P49720,Q92530 15
Degradation of beta catenin by the destruction complex 0.4748167309109879 2.449822261498411 0.0142926747293881 0.9999999981013816 0.2191019917307299 50 P61289,P49721,P30154,P25787,P28070,P49841,P30153,Q9UL46,Q14997,P20618,P28072,P49720,Q92530 13
Cholesterol biosynthesis 0.6456785182008767 2.4377067608788248 0.014780758727092 0.999999999048575 0.2241212872205806 18 Q14534,Q16850,Q9BWD1,Q15800,Q9H2C2,Q15392 6
Class a 1 rhodopsin like receptors 0.8463821643143031 2.416594003807167 0.0156664803735553 0.9999999997286856 0.2324972353309542 7 Q9NRV9,P04083,P05067,P07602,P42892 5
Peptide ligand binding receptors 0.8463821643143031 2.416594003807167 0.0156664803735553 0.9999999997286856 0.2324972353309542 7 Q9NRV9,P04083,P05067,P07602,P42892 5
Rhoa gtpase cycle 0.4675125622252684 2.398055892652602 0.0164823499914075 0.9999999999146684 0.2380516864672509 52 Q13464,P30519,P27105,O75955,Q15904,O15173,Q14739,Q8NBN3,Q8TAA9,Q15836,Q13190,P02786 12
Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1 0.4694499269661339 2.3952598242565117 0.0166085913113209 0.9999999999286586 0.2380516864672509 50 P61289,P49721,P25786,P25787,Q12834,P28070,Q9UJX3,Q9UL46,Q9UJX6,Q14997,P28072,P20618,P49720,P28074,Q92530 15
Rac3 gtpase cycle 0.5281679406021411 2.392734353240849 0.0167233442822871 0.9999999999393764 0.2380516864672509 35 P50402,Q7L576,P02786,O15173,P49257,Q14739,Q8IZP0,Q8TAA9,P42167,P42166,Q15836,Q68EM7,Q9UQB8 13
Stabilization of p53 0.508367556957823 2.376154260450858 0.0174941474253258 0.9999999999796984 0.2464508505680184 39 P61289,P49721,P25787,P28070,P20618,Q14997,Q9UL46,P28072,P49720,Q92530 10
Glycerophospholipid biosynthesis 0.5565111719779021 2.3662102430388305 0.0179712356548182 0.9999999999896896 0.2464508505680184 29 Q96N66,P48651,P35790,Q8IV08,Q8NCC3,Q9HCL2,Q8WWI5,Q9NPH0,Q9C0D9 9
Ire1alpha activates chaperones 0.5776546483475096 2.360587713167818 0.0182460028893325 0.999999999993022 0.2464508505680184 25 P43307,Q9HCU5,Q9NWM8,P61421,O95070,P49840,Q9Y5M8,O14773,Q14999 9
Insertion of tail anchored proteins into the endoplasmic reticulum membrane 0.7047625328732292 2.355826738537699 0.0184815356407426 0.9999999999950068 0.2464508505680184 12 O43681,P50402,Q7L5D6,P46379,P09601,P05067,P51648,Q13190 8
Cross presentation of soluble exogenous antigens endosomes 0.508526149232346 2.341421200498642 0.0192104807387041 0.9999999999982288 0.2464508505680184 38 P61289,P49721,P25787,P28070,Q9UL46,Q14997,P20618,P28072,P49720,Q92530 10
Degradation of axin 0.508526149232346 2.341421200498642 0.0192104807387041 0.9999999999982288 0.2464508505680184 38 P61289,P49721,P25787,P28070,Q9UL46,Q14997,P20618,P28072,P49720,Q92530 10
Mitochondrial calcium ion transport 0.6447127445854236 2.325833336283949 0.0200274434872864 0.999999999999446 0.2495752204588884 16 Q10713,Q9Y277,Q9BPX6,P21796,P45880,Q8NE86,O95202,Q8WWC4 8
G1 s dna damage checkpoints 0.4932703541390852 2.3165867911116984 0.0205262515935602 0.9999999999997278 0.2511764997633031 41 P61289,P49721,P24941,P25786,P25787,P28070,O00231,P20618,Q14997,Q9UL46,P28072,P49720,P28074,Q92530 14
Cellular response to chemical stress 0.4153151983522363 2.30881712559526 0.0209537312951835 0.999999999999852 0.2541778709285305 78 P13073,P30519,P49721,O75880,Q96I36,P61289,P25787,P28070,P00403,P09601,P20618,Q14997,P49720,P28072,Q9P0S2,Q9UL46,Q8TCT9,Q92530 18
Disorders of transmembrane transporters 0.4121391217901309 2.2896027492877513 0.0220443554800362 0.9999999999999688 0.2594678067378611 76 P35613,P11166,P61289,P49721,P25787,Q9UBV2,P53985,P28070,Q9BUN8,Q9BTX1,Q8N1F7,Q9UL46,Q14997,P20618,P28072,P49720,P08195,Q92530 18
Auf1 hnrnp d0 binds and destabilizes mrna 0.4851866463492749 2.282456694535595 0.022462391413816 0.9999999999999828 0.2594678067378611 42 P61289,P49721,P25786,P25787,P28070,Q14103,P20618,Q14997,Q9UL46,P28072,P49720,P28074,Q92530 13
Regulation of runx2 expression and activity 0.471094883092798 2.2819936991634644 0.0224897122548564 0.9999999999999836 0.2594678067378611 45 P61289,P49721,P25787,P28070,P49841,P20618,Q14997,Q9UL46,P28072,P49720,Q92530 11
Transcriptional regulation by runx2 0.45369443536098 2.2786699591092625 0.0226866918027019 0.9999999999999876 0.2594678067378611 54 P17931,P61289,P49721,P25786,P25787,P28070,P49841,P31751,Q9UL46,Q14997,P20618,P28072,P49720,P28074,Q92530 15
Asymmetric localization of pcp proteins 0.4971515349979412 2.2754690610116106 0.0228778066155963 0.9999999999999905 0.2594678067378611 39 P61289,P49721,P25787,P28070,Q9UL46,Q14997,P20618,P28072,P49720,Q92530 10
Stimuli sensing channels 0.7308916817219244 2.2576144447510686 0.0239697073051918 0.999999999999998 0.2612323569589271 10 P51798,P27105,Q9C0H2 3
Degradation of dvl 0.4940785098755242 2.247704731556396 0.0245950241011581 0.9999999999999992 0.26385550965033 39 P61289,P49721,P25787,P28070,Q9UL46,Q14997,P20618,P28072,P49720,Q92530 10
Regulation of tp53 expression and degradation 0.7643757735202938 2.243724234698732 0.0248501498294697 0.9999999999999994 0.26385550965033 8 P31751,P30154 2
Regulation of ras by gaps 0.4893438416391056 2.2414324515971473 0.0249980764224106 0.9999999999999996 0.26385550965033 40 P61289,P49721,P25787,P28070,Q9UL46,Q14997,P20618,P28072,P49720,Q92530 10
Heparan sulfate heparin hs gag metabolism 0.8486429487114863 2.235142809429759 0.0254079746721218 0.9999999999999998 0.2645083930418656 6 P54802,P16278,Q7LGA3 3
Cellular response to hypoxia 0.4737163837660246 2.174184097636028 0.0296913121605879 1.0 0.2903127678027422 42 P61289,P49721,P25787,P28070,Q9UL46,Q14997,P20618,P28072,P49720,Q92530 10
Switching of origins to a post replicative state 0.4357502924682769 2.173913048544468 0.0297116659074072 1.0 0.2903127678027422 60 P25787,P28070,Q9UJX6,Q96DE5,Q9Y619,P33991,Q14566,P24941,P25786,P28072,P28074,P61289,O00231,Q9UJX3,P33993,Q14997,P49721,Q9UL46,P20618,P49720,P49736,Q92530 22
Orc1 removal from chromatin 0.4454380335675109 2.167625045659536 0.030187226559438 1.0 0.2903127678027422 52 P61289,P49721,Q14566,P25786,P25787,P28070,O00231,Q9UL46,Q14997,P20618,P28072,P49720,P49736,P28074,Q9Y619,P33991,Q92530 17
Hedgehog off state 0.441922731638142 2.166027234250829 0.0303091058803481 1.0 0.2903127678027422 55 P61289,P49721,P10644,P25787,P28070,P49841,Q9UL46,Q14997,P20618,P28072,P49720,Q92530 12
Dectin 1 mediated noncanonical nf kb signaling 0.4727540402032246 2.165048273784467 0.0303839886015773 1.0 0.2903127678027422 42 P61289,P49721,P25787,P28070,P20618,Q14997,Q9UL46,P28072,P49720,Q92530 10
Degradation of gli1 by the proteasome 0.4669495545439596 2.1511423900276623 0.0314649625369942 1.0 0.2985960730551497 43 P61289,P49721,P25787,P28070,P20618,Q14997,Q9UL46,P28072,P49720,Q92530 10
Diseases of carbohydrate metabolism 0.707902140745222 2.139768724686474 0.0323734619095799 1.0 0.3030938212339863 10 P54802,P16278,P15586,P10253 4
Hedgehog on state 0.4639123921306498 2.121806268931532 0.0338540099994886 1.0 0.3037464526802906 43 P61289,P49721,P25787,P28070,Q9UL46,Q14997,P20618,P28072,P49720,Q92530 10
Respiratory electron transport 0.4321372957779989 2.1170618326562076 0.0342546004058319 1.0 0.3037464526802906 59 P13073,O75880,Q9UDW1,P00403,Q86Y39,O96000,O95168,O75306,Q9P0J0,O14949,P03886,Q9P0S2,O43676 13
Apc c mediated degradation of cell cycle proteins 0.4348402485717765 2.1165369322973113 0.034299167568575 1.0 0.3037464526802906 57 P61289,P49721,P24941,P25786,P25787,Q12834,P28070,O00231,Q9UJX3,Q9UL46,Q9UJX6,Q14997,P28072,P20618,P49720,Q96DE5,P28074,Q92530 18
Retrograde transport at the trans golgi network 0.5739539365975777 2.115363101453849 0.0343990121223594 1.0 0.3037464526802906 21 P53365,P11717,O43752,O60499,Q9UID3,Q96MW5,Q15836,Q5VZE5,P20645,Q9H9E3,P40616 11
Phospholipid metabolism 0.4631540455547857 2.114468646512156 0.0344752599339919 1.0 0.3037464526802906 43 Q10713,Q96N66,Q9UBF8,P48651,P35790,Q8IV08,Q8NCC3,Q8NF37,Q8WWI5,Q9NTJ5,Q9NPH0,Q9HCL2,Q9C0D9 13
Ion transport by p type atpases 0.7028289845010406 2.1135532511594626 0.034553442264855 1.0 0.3037464526802906 10 P05023,Q9HD20,Q13555,P16615,P35670 5
Signaling by the b cell receptor bcr 0.4432688765375907 2.100929524152392 0.0356471532611795 1.0 0.3055914578540505 47 P61289,O43865,P49721,P25787,P28070,Q9UL46,Q14997,P20618,P28072,P49720,Q92530 11
Cargo concentration in the er 0.640086610978137 2.098246491894989 0.0358833765841055 1.0 0.3055914578540505 13 Q15436,Q15363,Q9HCU5,Q96PC5,Q13190 5
Metabolism of polyamines 0.473131843212605 2.0916317248100897 0.0364714723239072 1.0 0.3071867820549691 40 P61289,P49721,P25787,P28070,Q9UL46,Q14997,P20618,P28072,P49720,Q92530 10
The role of gtse1 in g2 m progression after g2 checkpoint 0.4361596534438333 2.059376122369097 0.0394582213280749 1.0 0.3187908661213637 51 P61289,P49721,P25787,P28070,Q9UL46,Q14997,P20618,P28072,P49720,Q92530 10
Mapk6 mapk4 signaling 0.4365105257776218 2.0539642186443183 0.0399791549840045 1.0 0.3187908661213637 50 P61289,Q9HCE1,P49721,P25786,P25787,P28070,O00231,Q9UL46,Q14997,P20618,P28072,P49720,P28074,Q92530 14
Signaling by hedgehog 0.4250445158339161 2.053834777413331 0.0399916857141495 1.0 0.3187908661213637 60 P61289,P49721,P10644,P25787,Q9UBV2,P28070,P49841,Q9UL46,Q14997,P20618,P28072,P49720,Q92530 13
Ub specific processing proteases 0.393801065333464 2.043860842935489 0.0409672964241163 1.0 0.3247123779070584 77 P61289,P49721,Q9Y277,P25786,P25787,P21796,Q12834,P28070,P45880,Q92890,Q15388,P20618,Q14997,P49720,P28072,Q9UL46,Q92530 17
Copi dependent golgi to er retrograde traffic 0.4351421251005256 2.0395486847899265 0.0413952975039262 1.0 0.3262510735478932 50 Q15363,Q86Y91,P49755,O15260,Q6NUQ1,Q9BVK6,Q9H0U4,Q02224,Q9Y3B3,Q9P2W9 10
Regulation of runx3 expression and activity 0.4734395993608632 2.0261071531611825 0.0427538052380143 1.0 0.3307379650829191 38 P61289,P49721,P25787,P28070,Q9UL46,P20618,P49720,P28072,Q92530 9
Purinergic signaling in leishmaniasis infection 0.8676667557754221 2.0233059976163297 0.0430416089257998 1.0 0.3307379650829191 5 P09601 1
The nlrp3 inflammasome 0.8676667557754221 2.0233059976163297 0.0430416089257998 1.0 0.3307379650829191 5 P09601 1
Inflammasomes 0.8676667557754221 2.0233059976163297 0.0430416089257998 1.0 0.3307379650829191 5 P09601 1
Cyclin a cdk2 associated events at s phase entry 0.4488982472352062 2.017535020974293 0.043639710152074 1.0 0.3309019088000562 44 P61289,P49721,P25787,P28070,P31751,Q9UL46,P20618,P49720,P28072,Q92530 10
Uch proteinases 0.4396763582686881 2.015206193681255 0.0438830488372834 1.0 0.3309019088000562 46 P61289,P49721,P25786,P25787,Q16186,P28070,O00231,Q9UL46,Q14997,P20618,P28072,P49720,P28074,Q92530 14
Transport to the golgi and subsequent modification 0.3924223602693018 2.005863139547438 0.044870851913711 1.0 0.3329512681895052 75 O15027,Q13561,Q15363,O14579,P04066,P49257,Q8IUR0,Q96PC5,Q9Y3B3,Q9HCU5,O95249,Q9BVK6,Q9H0U4,P84085,O75935,Q13190,Q15436,P49755,Q9UJW0,Q9H9E3 20
Formation of atp by chemiosmotic coupling 0.6802254324040262 1.995833278015869 0.0459520732351621 1.0 0.337384958752901 10 O75964,P00846 2
Transport of inorganic cations anions and amino acids oligopeptides 0.6796188621940984 1.9926537659214816 0.0462993733614713 1.0 0.3375973297701952 10 P30825,Q70HW3,Q9UBX3,P55011 4
Signaling by ctnnb1 phospho site mutants 0.747430900354954 1.967372110232361 0.0491403272262596 1.0 0.3408078293374598 7 P30154,P30153 2
Beta catenin phosphorylation cascade 0.747430900354954 1.967372110232361 0.0491403272262596 1.0 0.3408078293374598 7 P30154,P30153 2
Disassembly of the destruction complex and recruitment of axin to the membrane 0.747430900354954 1.967372110232361 0.0491403272262596 1.0 0.3408078293374598 7 P30154,P30153 2
Pink1 prkn mediated mitophagy 0.6745079351357511 1.965821263337337 0.0493192607059744 1.0 0.3408078293374598 10 P21796,Q9NS69,Q8N4H5 3
Tnfr2 non canonical nf kb pathway 0.4470109418946323 1.957076460029795 0.050338479573099 1.0 0.3459220640614439 43 P61289,P49721,P25787,P28070,P20618,Q14997,Q9UL46,P28072,P49720,Q92530 10
Cristae formation 0.555886218939157 1.9483476533834865 0.0513733787977499 1.0 0.3492560709367543 20 Q9BUR5,P00846,Q13505,O75431,P24539,Q9NX63,Q9NVH1,Q9Y512,O75964 9
Iron uptake and transport 0.5691361059265951 1.9466664894750456 0.0515747316222017 1.0 0.3492560709367543 18 P30519,Q15904,Q9Y487,P09601,Q93050,P02786 6
Golgi to er retrograde transport 0.3874809903597832 1.9421027160999769 0.052124666778456 1.0 0.3509475296263346 75 Q13561,Q15363,Q86Y91,P49755,O15260,Q6NUQ1,Q9BVK6,Q9H2M9,Q9H0U4,Q9P2W9,Q9UJW0,Q02224,Q9Y3B3,Q10472,O75935 15
Er to golgi anterograde transport 0.3917261181839703 1.938996854764978 0.0525017211439462 1.0 0.3509475296263346 73 O15027,Q13561,Q15363,O14579,P49257,Q8IUR0,Q96PC5,Q9Y3B3,Q9HCU5,O95249,Q9BVK6,Q9H0U4,P84085,O75935,Q13190,Q15436,P49755,Q9UJW0,Q9H9E3 19
Mitophagy 0.6106941262222444 1.9265760099986529 0.0540324907612763 1.0 0.3542053878385811 13 P21796,Q9NS69,Q8N4H5 3
Downstream signaling events of b cell receptor bcr 0.437915154494313 1.9081736320360696 0.0563687784255513 1.0 0.3657416088541586 44 P61289,P49721,P25787,P28070,Q9UL46,Q14997,P20618,P28072,P49720,Q92530 10
Cdt1 association with the cdc6 orc origin complex 0.4453577913557374 1.9016435195181844 0.0572177743873547 1.0 0.3695314595849994 42 P61289,P49721,P25786,P25787,P28070,P20618,Q14997,Q9UL46,P28072,P49720,P28074,Q9Y619,Q92530 13
Platelet homeostasis 0.638696729677759 1.8975245134787504 0.0577587466105684 1.0 0.3713062282107972 11 P16615,P30154,P30153 3
The citric acid tca cycle and respiratory electron transport 0.3999462042052161 1.885193983165065 0.0594036528698533 1.0 0.3790496267514149 101 P35613,P00846,P21796,P00403,O96000,Q9P0J0,P03886,O95168,O43676,O75964,P13073,O75880,Q86Y39,Q13423,P53985,Q9UDW1,Q9P0S2,O14949,P24539 19
Costimulation by the cd28 family 0.584658538315456 1.873847283893308 0.0609514770901373 1.0 0.3847389617228128 14 P31751,P30154 2
Intra golgi traffic 0.5755452892154174 1.854936750896281 0.0636052591366791 1.0 0.3908781343421471 15 O43752,O95249,Q9H9E3,O00461 4
Transport of vitamins nucleosides and related molecules 0.722611036322516 1.8512163501510357 0.0641384344929394 1.0 0.392425947884432 7 P12235,Q8TB61 2
Diseases associated with glycosaminoglycan metabolism 0.8238490942903731 1.8432186468998013 0.0652970934207772 1.0 0.3977705035894511 5 Q8NCH0 1
Ctla4 inhibitory signaling 0.7575313962949388 1.8374787507623471 0.0661392505844067 1.0 0.4011489328923799 6 P31751,P30154 2
Interleukin 1 signaling 0.4170747304306842 1.8337827595401848 0.066686247913305 1.0 0.4027156529829459 48 P61289,P49721,P25787,P28070,P05067,Q9UL46,Q14997,P20618,P28072,P49720,Q92530 11
Transferrin endocytosis and recycling 0.6258578532788672 1.826362292377561 0.067795707820726 1.0 0.4076509155599693 11 P02786,Q93050,Q15904,Q9Y487 4
Metabolism of steroids 0.4295467400762904 1.824143192402408 0.0681304271357483 1.0 0.407905347014459 44 Q14534,Q16850,Q9BWD1,P38435,Q9H2C2,Q15800,Q9HCL2,Q99538,Q14849,P04062,Q15392 11
Signaling by notch4 0.4275419574502632 1.8039240689300229 0.0712432111973617 1.0 0.419168154407161 44 P61289,P49721,P25787,P28070,Q92542,Q9UL46,P20618,P49720,P28072,Q92530 10
Rnd1 gtpase cycle 0.5725657561019617 1.799294367720889 0.0719721285659544 1.0 0.419168154407161 14 Q9BXS4,Q8TAA9,O75976,P51648 4
Keratan sulfate keratin metabolism 0.8130537546722029 1.79839173688486 0.0721149512958556 1.0 0.419168154407161 5 P16278,P15586,P06865 3
Scf skp2 mediated degradation of p27 p21 0.4337233383198987 1.787889910721354 0.0737937709891203 1.0 0.4236309075301351 42 P61289,P49721,P24941,P25786,P25787,P28070,O00231,P20618,Q9UL46,P49720,P28072,P28074,Q92530 13
Copi mediated anterograde transport 0.4068619239223884 1.761885306358434 0.0780886776879705 1.0 0.4388408157886711 53 O14579,Q13561,Q15363,P49755,O95249,Q9BVK6,Q9H0U4,Q9UJW0,P84085,Q9Y3B3,Q9H9E3,O75935,Q13190 13
Constitutive signaling by akt1 e17k in cancer 0.8042692242191072 1.761787639509472 0.0781051839026356 1.0 0.4388408157886711 5 P31751,P49841 2
Negative regulation of notch4 signaling 0.434573788673236 1.7604547917032831 0.0783307262590531 1.0 0.4388408157886711 41 P61289,P49721,P25787,P28070,Q9UL46,P20618,P49720,P28072,Q92530 9
Glycogen breakdown glycogenolysis 0.699624818263888 1.742471519077149 0.0814259708866877 1.0 0.4498733529556564 7 P10253 1
Diseases of glycosylation 0.527692195730898 1.717688741278923 0.0858534040393244 1.0 0.4598986344483381 19 P10619,P06865,Q8NCH0,Q2TAA5,Q9BT22,P16278 6
Mitotic g1 phase and g1 s transition 0.3713295938561255 1.7164190593145665 0.0860853706533584 1.0 0.4598986344483381 80 P25787,P28070,Q9NR33,P30153,Q9Y619,P33991,Q14566,P25786,P28072,P31350,P28074,P49643,P61289,P30154,O00231,P33993,P49721,P31751,P00374,P20618,Q9UL46,P49720,P49736,Q92530 24
Opioid signalling 0.5270461454061582 1.7132490926964543 0.086666723476936 1.0 0.4598986344483381 19 O43865,P10644,P30154,P63218,P30153,Q13555 6
Gamma carboxylation hypusine formation and arylsulfatase activation 0.6406751779712855 1.705321910234754 0.0881344034251072 1.0 0.4598986344483381 9 O43681,P38435,P49366,O60725 4
Pten regulation 0.3898355367174341 1.6960527447932214 0.0898758916970323 1.0 0.4626452727577865 63 P46934,P61289,P49721,P25786,P25787,P28070,P31751,Q9UL46,Q14997,P20618,P28072,P49720,Q92530 13
Purine salvage 0.7857035296059496 1.6840677733031773 0.0921685716229228 1.0 0.4726178754799147 5 P00813 1
Transcriptional regulation by runx3 0.4193636653861007 1.6824025356427854 0.0924908100401553 1.0 0.4726178754799147 43 P61289,P49721,P25787,P28070,Q9UL46,P20618,P49720,P28072,Q92530 9
Cyclin a b1 b2 associated events during g2 m transition 0.5846585648737334 1.6792106163709024 0.093111003658322 1.0 0.4740505478224789 12 Q99640,P30154 2
Intracellular signaling by second messengers 0.3714110023339452 1.6746596065360235 0.0940010370281569 1.0 0.474991156861051 84 O43865,P25787,P28070,P30153,Q13555,P25786,P28072,P46934,P61289,P10644,P30154,P49841,Q14997,P49721,P31751,P49840,P20618,Q9UL46,P49720,Q92530 20
Signaling by insulin receptor 0.5406742855297562 1.671547331555051 0.0946136179232719 1.0 0.474991156861051 16 P31751,Q93050,Q15904,Q9Y487 4
Peptide hormone metabolism 0.566899367579744 1.6652055995843629 0.0958717442012422 1.0 0.4755277071642899 13 Q15005,O60645,P67812 3
Synthesis of pa 0.6396987048783394 1.626493387481003 0.1038447389083585 1.0 0.4995290026798626 8 Q9HCL2,Q9NPH0 2
Mucopolysaccharidoses 0.8873072360616913 1.6214880075952365 0.1049130198659917 1.0 0.5029335488421256 4 P54802,P16278,P15586 3
Signaling by notch 0.3866516965153055 1.6129937981282187 0.1067458551935658 1.0 0.5064981904592665 60 Q9H488,P61289,Q9HCE1,P49721,Q15363,P25786,P25787,Q9UBV2,P28070,Q92542,Q9UL46,P16615,P20618,P28072,P49720,P28074,Q92530 17
Class i peroxisomal membrane protein import 0.6342528240729525 1.5986907706622584 0.1098893293541474 1.0 0.516146849996753 8 Q8TB36,Q9NR77,P40855,P51648 4
Nucleotide salvage 0.6332486884255046 1.5935577268991852 0.1110351290837221 1.0 0.5174180000711506 8 P00813 1
Sialic acid metabolism 0.7625625287296014 1.5865609487485397 0.1126121178661732 1.0 0.5174180000711506 5 P10619 1
Initiation of nuclear envelope ne reformation 0.5147024536053575 1.5820490101233555 0.1136383825662992 1.0 0.5174217455222243 18 P50402,P42167,Q14739,P30153,Q8IXJ6,Q86XL3 6
Keratan sulfate degradation 0.8750235025953386 1.5737965815692614 0.1155344846183585 1.0 0.5182334599440843 4 P16278,P06865 2
Proton coupled monocarboxylate transport 0.9244220509780676 1.5481079445379973 0.1215963096610104 1.0 0.5300839124284673 2 P53985 1
Unfolded protein response upr 0.408033015394557 1.5330290026171696 0.1252687090870199 1.0 0.5394690810199324 42 P43307,O76024,Q9HCU5,Q9NWM8,P61421,O95070,P49840,Q9Y5M8,O14773,Q14999 10
Tcr signaling 0.3851712051893689 1.5211733965413916 0.1282163296430665 1.0 0.5394690810199324 53 P61289,P49721,P25786,P25787,P28070,O00231,Q13153,P49427,Q9UL46,Q14997,P20618,P28072,P49720,P28074,Q92530 15
Synthesis secretion and deacylation of ghrelin 0.9170124481327806 1.5177816084050508 0.1290694629962638 1.0 0.5394690810199324 2 P67812 1
Synthesis secretion and inactivation of glucose dependent insulinotropic polypeptide gip 0.9170124481327806 1.5177816084050508 0.1290694629962638 1.0 0.5394690810199324 2 P67812 1
Runx1 regulates transcription of genes involved in differentiation of hscs 0.4028205994112061 1.5152161573949965 0.1297176726264444 1.0 0.5394690810199324 43 P61289,P49721,P25787,P28070,P20618,Q14997,Q9UL46,P28072,P49720,Q92530 10
Insulin receptor recycling 0.5906060721251193 1.5152104128214552 0.1297191269322466 1.0 0.5394690810199324 10 Q93050,Q15904,Q9Y487 3
Mitotic g2 g2 m phases 0.369381139218993 1.5152046942015125 0.1297205746801657 1.0 0.5394690810199324 97 Q13561,P25787,P28070,P30153,P25786,P41208,O43805,Q15154,P28072,Q99640,P61289,P30154,Q14997,O75935,P49721,O95684,Q9H6D7,P20618,Q96CW5,P49720,Q9UL46,Q92530 22
Maturation of sars cov 2 nucleoprotein 0.6853181230683978 1.511412837086758 0.130683300726683 1.0 0.5394690810199324 6 P49841 1
Vitamin d calciferol metabolism 0.946042099021644 1.5084438954634496 0.1314409556943832 1.0 0.5408853486538777 3 P04062,P38435 2
Clec7a dectin 1 signaling 0.3855371264377994 1.505028626813362 0.1323167170432031 1.0 0.5428877066919658 50 P61289,O43865,P49721,P25787,P28070,Q9UL46,Q14997,P20618,P28072,P49720,Q92530 11
G protein mediated events 0.5637601292938356 1.4756397727640462 0.1400406220318419 1.0 0.5599234275646776 11 O43865,Q13555,P10644 3
Heme degradation 0.935965239996012 1.4706180020562578 0.1413944527180213 1.0 0.5599234275646776 3 P09601 1
Mastl facilitates mitotic progression 0.6742489061964275 1.4607401367499953 0.1440867697537897 1.0 0.5648320485501651 6 P30154 1
Fceri mediated nf kb activation 0.3865808026757477 1.460533457686249 0.1441435191998987 1.0 0.5648320485501651 46 P61289,P49721,P25787,P28070,Q9UL46,Q14997,P20618,P28072,P49720,Q92530 10
Synthesis of substrates in n glycan biosythesis 0.5019058668275883 1.4541271714085968 0.1459110516632118 1.0 0.5701566304486849 17 P10619,P16278,Q86YN1 3
Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein 0.4797786293802518 1.4490304358561457 0.1473290830764584 1.0 0.5740895834962556 21 P16278,Q9Y5P6,P10619,Q86YN1 4
Metalloprotease dubs 0.6380559064531468 1.4462791888963518 0.1480989104448702 1.0 0.575481838636752 7 O95630,Q9NXR7,Q9NWV8 3
Cytosolic iron sulfur cluster assembly 0.6682016126585768 1.4329948098558 0.1518593205636387 1.0 0.5884548671841 6 O75027 1
Interleukin 1 family signaling 0.3780895307231902 1.4285086210660305 0.1531455150001226 1.0 0.5917949956375931 51 P61289,P49721,P25787,P28070,P05067,Q9UL46,Q14997,P20618,P28072,P49720,Q92530 11
Pre notch processing in golgi 0.8367456571180981 1.4245591112164149 0.1542846866403804 1.0 0.5929122255188174 4 Q9UBV2,Q15363 2
Platelet sensitization by ldl 0.6659714418545504 1.4227523832411608 0.1548079493671306 1.0 0.5932887070526023 6 P30154 1
Akt phosphorylates targets in the cytosol 0.8349761101093504 1.4176424994650527 0.1562951655326028 1.0 0.5947224714600715 4 P31751,P49841 2
Maturation of sars cov 1 nucleoprotein 0.8924125666864258 1.417074875517777 0.1564610372945134 1.0 0.5947224714600715 2 P49841 1
Synthesis of pe 0.9190342273747 1.4070194613166598 0.1594216180418135 1.0 0.5986700862271099 3 P35790 1
Chondroitin sulfate dermatan sulfate metabolism 0.832065986386223 1.4062653124896214 0.1596453563272293 1.0 0.5986700862271099 4 Q8NCH0 1
G alpha s signalling events 0.6614669418570984 1.402048747459676 0.1609006903708691 1.0 0.5995611468635881 6 P63218 1
Metabolism of fat soluble vitamins 0.8297746144721285 1.3973051844101958 0.1623218174771707 1.0 0.6009574945909874 4 P09455,Q8N0U8,Q6NUM9 3
Downregulation of erbb2 signaling 0.7113790159500573 1.3688671159554244 0.1710408165377877 1.0 0.616082690620084 5 P31751 1
Tcf dependent signaling in response to wnt 0.3636652176056731 1.3678632054453663 0.1713548988964821 1.0 0.616082690620084 62 P61289,P49721,P30154,P25787,P28070,P49841,P31751,P30153,Q9UL46,Q14997,P20618,P28072,P49720,Q92530 14
Selective autophagy 0.4221070620959488 1.3547344725045187 0.1755021705800772 1.0 0.624554918263285 32 Q9NS69,P54619,P21796,P08670,Q15388,Q8N4H5,P50542 7
Ion homeostasis 0.5388116794150372 1.332187269970896 0.182798658618851 1.0 0.6333038595526047 11 Q13555,O43865,P16615,P05023 4
Deubiquitination 0.3551590160883093 1.3321286646727224 0.1828179124743729 1.0 0.6333038595526047 96 P25787,P21796,P28070,P45880,Q9NWV8,Q14145,Q7Z434,P25786,P28072,P28074,P61289,Q16186,O00231,Q9NXR7,Q15388,Q14997,O95630,P49721,Q9Y277,Q92890,Q12834,P20618,Q9UL46,P49720,Q96K76,Q92530 26
Rhoc gtpase cycle 0.4034350797838718 1.322702382256666 0.1859343710089898 1.0 0.6333038595526047 36 Q13464,P27105,O75955,P42167,Q14739,Q8TAA9,P42166,Q15836,Q13190,P02786 10
Immunoregulatory interactions between a lymphoid and a non lymphoid cell 0.6985449782724418 1.3139702834765152 0.1888562047124613 1.0 0.6333038595526047 5 P10321,P04439 2
Hs gag degradation 0.8870441743255316 1.2868615742363714 0.1981425406277606 1.0 0.6534488041979339 3 P54802,P16278 2
Metabolism of folate and pterines 0.5598136668019649 1.2762917658052144 0.2018523998604191 1.0 0.660856434680628 9 Q9H2D1 1
C type lectin receptors clrs 0.3620662093727612 1.274760767579184 0.2023939308625026 1.0 0.660856434680628 55 P61289,O43865,P49721,P25787,P28070,Q9UL46,Q14997,P20618,P28072,P49720,Q92530 11
Formyl peptide receptors bind formyl peptides and many other ligands 0.8831900385413625 1.2723997619447849 0.2032311186222146 1.0 0.660856434680628 3 Q9NRV9,P05067 2
Neddylation 0.3377599616987372 1.2636640366913316 0.2063506384855964 1.0 0.6641082627251872 80 P61289,P49721,Q8N668,P25787,P28070,Q99627,P20618,Q14997,P49720,P28072,Q9UL46,Q9BTE7,Q9BT78,Q92530,Q14999 15
Hyaluronan metabolism 0.6865985752202728 1.2628092712700412 0.2066577320016458 1.0 0.6641082627251872 5 P06865 1
Hyaluronan uptake and degradation 0.6865985752202728 1.2628092712700412 0.2066577320016458 1.0 0.6641082627251872 5 P06865 1
Complex i biogenesis 0.4144357229554109 1.2591022147577793 0.2079934145869901 1.0 0.6641082627251872 31 Q86Y39,O96000,O95168,Q9P0J0,P03886,O43676 6
Negative regulation of mapk pathway 0.5130998574681708 1.2558048410895224 0.2091867359929771 1.0 0.6641082627251872 12 P30154,P30153 2
Nicotinate metabolism 0.7934986200973602 1.2553360410387129 0.2093567968631906 1.0 0.6641082627251872 4 P43490 1
Negative regulators of ddx58 ifih1 signaling 0.567754447601295 1.255030084028149 0.2094678391391271 1.0 0.6641082627251872 8 Q86UT6,Q7Z434,Q9UII4,Q96J02 4
Copii mediated vesicle transport 0.4193530857652046 1.2515625457153712 0.2107293095447036 1.0 0.6665927138658991 29 Q15436,O15027,Q15363,P49755,Q9HCU5,Q8IUR0,Q9H0U4,Q13190 8
Antigen presentation folding assembly and peptide loading of class i mhc 0.4856673271999979 1.249693629154852 0.2114114854740179 1.0 0.6672376068693551 14 P04439,Q15436,Q03518,Q9NZ08 4
Metabolism of lipids 0.3929883560550115 1.24585775489218 0.2128166217311493 1.0 0.6686468182769219 183 P04035,P06865,O95470,Q16850,P38435,Q15165,P50897,Q9NPH0,Q96G23,Q14739,Q96N66,Q14914,P35790,O43772,Q9H2C2,P06280,Q99538,Q8WWI5,Q14849,Q9NZJ7,O14734,Q15392,Q16739,Q9UMR5,P10619,Q9H7Z7,Q9BWD1,Q9UBF8,Q8IV08,Q9NZD2,Q8NCC3,P07602,Q8NF37,Q9P035,P04062,Q9C0D9,P16278,P17900,Q06136,Q15436,Q9NRA0,P50416,Q14534,O15269,P48651,Q13510,Q15800,Q9HCL2,P51648,P23786,O15121,Q53GQ0 52
Fc epsilon receptor fceri signaling 0.3582891222679469 1.2391889481770064 0.2152755324538944 1.0 0.6689382845259801 56 P61289,O43865,P49721,P25787,P28070,Q9UL46,Q14997,P20618,P28072,P49720,Q92530 11
Leishmania infection 0.3656814758639329 1.2365468732907272 0.2162553536961775 1.0 0.6689382845259801 46 Q7L576,O43865,P10644,P63218,P46108,P09601,P05067,Q9UQB8 8
Nicotinamide salvaging 0.8733984987707379 1.2356865633608765 0.216575093995234 1.0 0.6689382845259801 3 P43490 1
Endosomal sorting complex required for transport escrt 0.480969567742857 1.2194640814147668 0.2226681007175752 1.0 0.6745690201146587 14 A5D8V6,Q9BRG1,Q9UQN3,O75351,Q9H9H4 5
Methylation 0.5905694393821532 1.21425969715537 0.2246485706542123 1.0 0.6766348614216535 7 Q99707,P21964,P78417 3
Synthesis secretion and inactivation of glucagon like peptide 1 glp 1 0.867390300720777 1.2131828726470608 0.2250599108958044 1.0 0.6766348614216535 3 P67812 1
Incretin synthesis secretion and inactivation 0.867390300720777 1.2131828726470608 0.2250599108958044 1.0 0.6766348614216535 3 P67812 1
Vitamin c ascorbate metabolism 0.8667506026271373 1.210788130140925 0.2259766155321254 1.0 0.6779298465963763 3 P78417 1
Wnt ligand biogenesis and trafficking 0.6700545394823321 1.1919169410694148 0.2332938147777712 1.0 0.6844492022722964 5 Q9UBQ0 1
Darpp 32 events 0.5288349372566855 1.1739280945264166 0.2404238282139892 1.0 0.6944082694068049 10 P30154,P30153 2
Pyruvate metabolism 0.4646845468298706 1.1695092760223285 0.2421985061565212 1.0 0.6944082694068049 16 P35613,P21796,P53985 3
Regulation of glycolysis by fructose 2 6 bisphosphate metabolism 0.6647294515142943 1.1691007734863796 0.2423630323275063 1.0 0.6944082694068049 5 P30154 1
Rhob gtpase cycle 0.4142763983483427 1.168111946833559 0.2427616119528002 1.0 0.6944082694068049 27 Q13464,P27105,P02786,Q8TAA9,O75955 5
Rac1 gtpase cycle 0.3558122937024309 1.167551102488855 0.2429878837284083 1.0 0.6944082694068049 47 P50402,Q7L576,P02786,Q14739,Q8TAA9,Q15836,Q68EM7,Q96F07,Q9UQB8 9
Surfactant metabolism 0.8310610551274457 1.1669471935513456 0.2432316955700362 1.0 0.6944082694068049 2 Q07065 1
Synthesis of pc 0.6635798958055428 1.164176054996653 0.2443526719556557 1.0 0.6944082694068049 5 P35790,Q8WWI5 2
Synaptic adhesion like molecules 0.6097358587251626 1.1632306068671143 0.2447359516386851 1.0 0.6944082694068049 6 O95197 1
Synthesis of dna 0.3359679454603848 1.1628026464482744 0.2449095831886365 1.0 0.6944082694068049 87 P25787,P28070,Q9NR33,Q9UJX6,Q96DE5,Q9Y619,P33991,Q14566,P24941,P25786,P28072,P28074,P35250,P49643,P61289,O00231,Q9UJX3,P33993,Q14997,P40937,P49005,P49721,P56282,P20618,Q9UL46,P49720,P49736,Q92530 28
The canonical retinoid cycle in rods twilight vision 0.8292827504445768 1.1597477144789314 0.2461515373606162 1.0 0.6961971955385393 2 P09455 1
Endosomal vacuolar pathway 0.8485028164838466 1.1426000957804543 0.253204665767941 1.0 0.7092781300126058 3 P04439,Q9UIQ6 2
Diseases associated with glycosylation precursor biosynthesis 0.5457638422441236 1.1402890489067057 0.25416589868767 1.0 0.7103611771837864 8 P10619 1
Tp53 regulates metabolic genes 0.3789808068544975 1.1341737814881532 0.2567216595128383 1.0 0.7119815407960427 38 P13073,O75880,Q9HCE1,Q96I36,P54619,Q04917,P31751,P00403,P62258,Q9P0S2 10
Interconversion of nucleotide di and triphosphates 0.4476377657489746 1.1193830145198251 0.2629767740717421 1.0 0.7206642256273729 18 Q9H773,Q9Y3D8,P17812,P31350 4
Budding and maturation of hiv virion 0.4898547351752952 1.1164098890735703 0.2642467224329157 1.0 0.7206642256273729 12 A5D8V6,Q9H9H4,O75351 3
Pcp ce pathway 0.3490616948645238 1.1038276600963983 0.269667903783146 1.0 0.7206642256273729 51 P61289,P49721,P25787,P28070,Q9UL46,Q14997,P20618,P28072,P49720,Q92530 10
Ros and rns production in phagocytes 0.5265900169898944 1.0975129102649888 0.2724172402572424 1.0 0.7226174877081921 9 Q93050,Q9Y487 2
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane 0.749204007939237 1.082388504887151 0.2790799339148297 1.0 0.7226174877081921 4 P12235 1
Rhod gtpase cycle 0.3992613686719778 1.0812257476508995 0.2795967074381575 1.0 0.7226174877081921 29 P50402,O15173,P49257,Q14739,Q8TAA9,Q9Y6M7,P42167,P12814,Q15836,Q68EM7,Q86Y07,P42166 12
Creb1 phosphorylation through the activation of camkii camkk camkiv cascasde 0.8067575577949027 1.0689682570068422 0.2850839730914192 1.0 0.7226174877081921 2 Q13555 1
Camk iv mediated phosphorylation of creb 0.8067575577949027 1.0689682570068422 0.2850839730914192 1.0 0.7226174877081921 2 Q13555 1
Mapk family signaling cascades 0.3329107294906336 1.0682630725240014 0.2854018608554476 1.0 0.7226174877081921 92 P25787,P28070,P30153,Q13555,P25786,P28072,P49356,P61289,P30154,Q99956,Q14997,Q14168,P49721,Q9Y4G8,P20618,Q9UL46,P49720,Q92530,O60725 19
Unwinding of dna 0.5209908029314444 1.0673634113022996 0.2858077639161749 1.0 0.7226174877081921 9 P33993,P33991,Q14566,P49736 4
Sulfur amino acid metabolism 0.4929418913783923 1.0664017822131402 0.2862420563983427 1.0 0.7226174877081921 11 Q13126 1
Neutrophil degranulation 0.3797745074164703 1.063815359234365 0.2874123520176512 1.0 0.7226174877081921 181 O43681,P10321,O15126,P25787,P08236,P07384,Q92542,P04439,O00264,Q99536,P30519,Q7L576,P27105,P04066,O15260,P10253,P06280,Q9NZJ7,Q93050,O00560,Q13464,Q07065,P10619,Q969Q5,P15586,Q8WVQ1,Q9H7Z7,Q9BRF8,P07602,Q8NF37,P16278,P17900,P42785,Q9NQX7,P11279,Q13510,P20618,O15121,O00584 39
S phase 0.3376488592559722 1.062495744708977 0.2880106887779021 1.0 0.7226174877081921 99 P25787,P28070,Q9NR33,Q9UJX6,Q96DE5,Q9Y619,P33991,Q8WVM7,Q14566,P24941,P25786,P28072,P28074,P35250,P49643,P61289,P49841,O00231,Q9UJX3,P33993,Q14997,Q7Z5K2,P40937,P49005,P49721,P31751,P56282,P20618,Q9UL46,P49720,P49736,Q92530 32
Egr2 and sox10 mediated initiation of schwann cell myelination 0.519627112702672 1.0600222113334692 0.2891344946390517 1.0 0.7226174877081921 9 Q9NR77,Q16850,P04035 3
O linked glycosylation 0.7429161197326761 1.0579518864410924 0.2900773781181756 1.0 0.7226174877081921 4 Q10472 1
O linked glycosylation of mucins 0.7429161197326761 1.0579518864410924 0.2900773781181756 1.0 0.7226174877081921 4 Q10472 1
Phase ii conjugation of compounds 0.398560926028377 1.0557524829819018 0.2910813124066909 1.0 0.7226174877081921 28 Q9UI30,Q9NUJ1,Q8TB61,Q99707,Q99735,P78417,P48507,P21964 8
Signaling by interleukins 0.3447578037788499 1.0556699808168466 0.2911190165534079 1.0 0.7226174877081921 110 P25787,P28070,P04083,P09601,P05067,P30153,Q13126,P25786,Q07820,P28072,O14979,P61289,P30154,Q14997,P78417,P49721,P46108,O00170,P20618,Q9UL46,P49720,Q92530 22
Autophagy 0.3442691152595749 1.0538601720010594 0.2919469398155772 1.0 0.722762157736871 52 A5D8V6,Q9NS69,P54619,P21796,P08670,Q15388,Q9H9H4,Q8N4H5,P50542 9
Integrin signaling 0.5852149609728141 1.0498918376570403 0.2937678447575669 1.0 0.722762157736871 6 Q05397,P18031,P46108 3
Platelet aggregation plug formation 0.5852149609728141 1.0498918376570403 0.2937678447575669 1.0 0.722762157736871 6 Q05397,P18031,P46108 3
Interleukin 4 and interleukin 13 signaling 0.4762369381900176 1.0346740535312184 0.3008211572488826 1.0 0.7353831343112752 12 Q07820,P04083,P09601 3
Glycogen metabolism 0.4862884300357686 1.0278077174689395 0.3040402852949757 1.0 0.7389850210933321 11 Q04446,P46020,P10253 3
Vitamin b5 pantothenate metabolism 0.628747215472449 1.0152800460350009 0.3099723533297354 1.0 0.7510262107592843 5 Q9NRN7,Q9NVE7 2
Pp2a mediated dephosphorylation of key metabolic factors 0.8141092215221293 1.0150098229679212 0.3101011450877045 1.0 0.7510262107592843 3 P30154 1
G1 s specific transcription 0.4997648955598854 1.012293330146376 0.3113978229990932 1.0 0.7528595547378424 10 P04183,Q13547,P00374,P31350,Q9Y619,P04818 6
Signaling by wnt in cancer 0.5091545291342106 1.0036842087885562 0.3155308508798726 1.0 0.7602168168867398 9 P30154,P30153 2
Response to elevated platelet cytosolic ca2 0.3729219147266477 1.0024320033144496 0.3161349918231988 1.0 0.7603533837459604 35 Q08380,O94919,Q9Y6I9,Q8NBX0,P05067,P07602,Q9NZJ7,Q92520 8
Rhoq gtpase cycle 0.4002551984292449 0.9943955359590538 0.3200303405767561 1.0 0.7650037967784453 25 P27105,Q8TAA9,Q15836,Q68EM7,P02786 5
Rnd2 gtpase cycle 0.4437262855760858 0.979329296919726 0.3274172992304416 1.0 0.7754599236671922 14 Q07065,Q8TAA9,P51648 3
Beta catenin independent wnt signaling 0.3347057944914241 0.9721108188410192 0.3309954204576564 1.0 0.7754599236671922 57 P61289,P49721,P25786,P25787,P63218,P28070,Q9UL46,Q14997,P20618,P28072,P49720,Q92530 12
Vasopressin regulates renal water homeostasis via aquaporins 0.5681968073851398 0.9714834131508018 0.3313076089646212 1.0 0.7754599236671922 6 P10644 1
Glucagon signaling in metabolic regulation 0.5681968073851398 0.9714834131508018 0.3313076089646212 1.0 0.7754599236671922 6 P10644 1
Cdc42 gtpase cycle 0.3693104738592333 0.968912723894449 0.3325887364538735 1.0 0.7771545851811618 35 P27105,P02786,Q14739,Q8TAA9,Q15836,Q68EM7,Q9UQB8 7
Recruitment of mitotic centrosome proteins and complexes 0.3626126518586459 0.9560574006866172 0.339043235252233 1.0 0.7895915078077881 37 Q13561,P41208,O95684,Q9H6D7,O43805,P30153,Q15154,Q96CW5,O75935 9
Conversion from apc c cdc20 to apc c cdh1 in late anaphase 0.5000599829697682 0.9548476590041473 0.3396547420085869 1.0 0.7896972751699646 9 Q12834,Q9UJX6,Q9UJX3 3
Cargo recognition for clathrin mediated endocytosis 0.3699660561311899 0.9453917567667394 0.3444589090610026 1.0 0.7929375876899318 34 Q9NVZ3,Q14108,P11717,O14657,Q99627,Q9UHD9,P61201,Q15836,P20645,Q9BT78,P42566,P02786 12
Antigen processing ubiquitination proteasome degradation 0.3259097855871463 0.9412320536361084 0.3465859538675035 1.0 0.7939037859526559 95 P25787,P28070,P55786,Q9UJX6,Q14145,P25786,Q9UIQ6,P28072,P28074,P60604,P52888,P46934,P61289,Q6UWE0,Q9UJX3,Q9BSL1,Q14997,P49721,Q12834,O94822,P20618,Q9UL46,P49720,Q92530,Q14999 25
Vitamin b2 riboflavin metabolism 0.7726733847065805 0.93356029204121 0.3505307560922022 1.0 0.7951063491847513 2 Q969G6 1
Regulation of insulin secretion 0.433512637666173 0.9136128187832476 0.3609203282832944 1.0 0.8120707386374125 14 P11166,O43865,P10644 3
Adora2b mediated anti inflammatory cytokines production 0.4759677409628233 0.8805139998528284 0.378580924446706 1.0 0.8319172076059889 10 P10644,P63218 2
Glucagon like peptide 1 glp1 regulates insulin secretion 0.5219051828993592 0.8784059775529586 0.3797234416243982 1.0 0.8328839639403073 7 P10644 1
Regulation of mrna stability by proteins that bind au rich elements 0.3191369009765104 0.8735037192465114 0.3823885799050184 1.0 0.8333505091555966 66 P61289,P49721,Q01105,P25786,P25787,P28070,Q14103,Q9UL46,Q14997,P20618,P28072,P49720,P28074,Q92530 14
Rhoh gtpase cycle 0.3849449881405104 0.8724504111500262 0.3829627095405929 1.0 0.8333505091555966 25 Q13464,P11182,P27105,Q9BXS4,Q8TAA9,Q99707,Q15836,P02786 8
Regulation of cytoskeletal remodeling and cell spreading by ipp complex components 0.7560758743331366 0.8687836091078756 0.3849654999775751 1.0 0.8333505091555966 2 Q15404 1
Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways 0.458662647038371 0.8681493077043632 0.3853126010074263 1.0 0.8333505091555966 11 P09601 1
Signaling by gpcr 0.3332081418745959 0.85481903795927 0.3926513369886941 1.0 0.8430048763157453 45 Q9NRV9,Q13464,O43865,P10644,P30154,P31751,P04083,P30153,P05067,P07602,P42892,Q9NZJ7 12
Cyclin d associated events in g1 0.4706387965992218 0.8511617329940043 0.39467951675622 1.0 0.8431514944485865 10 P30154 1
Apc c cdc20 mediated degradation of cyclin b 0.4545365373093917 0.8444444648064047 0.3984210841899296 1.0 0.8451525950768195 11 Q9UJX2,Q12834,Q9UJX3,Q9UJX4,P06493,Q9UJX6,Q96DE5 7
Mtor signalling 0.4337401186102744 0.8440428641482937 0.3986454534484209 1.0 0.8451525950768195 13 P31751,P23588,P06730 3
Trans golgi network vesicle budding 0.3434276871621197 0.8307417767135064 0.4061195204050678 1.0 0.8532343856768922 40 Q9BXS5,P15586,P11717,Q9Y5X3,O14976,P55327,P05067,Q9H3P7,O60749,P20645,Q99523,O75976,P02786 13
Activation of ampk downstream of nmdars 0.5360626420323302 0.824721659155428 0.4095296321499022 1.0 0.8532343856768922 6 Q13885,Q13131,P54619,P68371 4
Ca dependent events 0.5106563811600421 0.8240364060093076 0.40991887232616 1.0 0.8532343856768922 7 Q13555,P10644 2
Dna replication pre initiation 0.3141185478380397 0.8236445069174844 0.4101415792099272 1.0 0.8532343856768922 67 P25787,P28070,Q9NR33,Q9Y619,P33991,Q14566,P25786,P28072,P28074,P49643,P61289,O00231,P33993,Q14997,P49721,Q9UL46,P20618,P49720,P49736,Q92530 20
Signaling by vegf 0.3619882867441853 0.8233721074656873 0.4102964196615071 1.0 0.8532343856768922 32 Q13464,Q7L576,O43865,Q96JJ3,P46108,Q8IZP0,P31751,Q13685,Q96F07,Q9UQB8 10
Recruitment of numa to mitotic centrosomes 0.3426225614492389 0.8228013080784011 0.4106209926999917 1.0 0.8532343856768922 40 Q13561,P41208,O95684,Q9H6D7,O43805,P30153,Q15154,Q96CW5,O75935 9
Circadian clock 0.4627136013932346 0.8076629245968199 0.4192846522478866 1.0 0.8665216146456323 10 P43490 1
Glycogen storage diseases 0.6755793216481938 0.8002853242246373 0.4235455039992606 1.0 0.8702757216297753 4 Q04446,P10253 2
Pexophagy 0.7359217545939547 0.7914534054716812 0.4286794559494107 1.0 0.875764712504598 2 P50542 1
Nrif signals cell death from the nucleus 0.7359217545939545 0.7914534054716812 0.4286794559494107 1.0 0.875764712504598 2 Q92542 1
Interferon gamma signaling 0.4597190736870543 0.7912820416473165 0.4287794255488462 1.0 0.875764712504598 10 P10321,P04439 2
Asparagine n linked glycosylation 0.3293145831694793 0.7797876431977571 0.435515880873127 1.0 0.8811283339184687 117 Q13561,Q15363,Q86YN1,P04066,Q9UBV2,Q9BUN8,Q8IUR0,Q96PC5,Q9Y3B3,P10619,Q9HCU5,O95249,Q9BVK6,Q2TAA5,P46977,P16278,O75935,Q13190,Q15436,Q9Y5P6,P49755,Q9BT22,Q9H9E3 23
Aquaporin mediated transport 0.500594619692183 0.775723511317398 0.4379122546467431 1.0 0.8811283339184687 7 P10644 1
Class i mhc mediated antigen processing presentation 0.328181970409403 0.7729814826509535 0.4395333396218532 1.0 0.8811283339184687 116 P10321,P25787,P28070,P55786,P04439,Q9UJX6,Q14145,P25786,Q9UIQ6,Q15836,P28072,P28074,P60604,P52888,P46934,P61289,Q6UWE0,O00231,Q9UJX3,Q9BSL1,Q03518,Q14997,Q15436,P49721,Q12834,O94822,P20618,Q9UL46,P49720,Q92530,Q14999,Q9NZ08 32
Erks are inactivated 0.4997080235601495 0.7714831173884735 0.4404206254881131 1.0 0.8811283339184687 7 P30154 1
Ptk6 regulates proteins involved in rna processing 0.7302904564315362 0.7701465973847089 0.4412129375626485 1.0 0.8811283339184687 2 P23246 1
Purine ribonucleoside monophosphate biosynthesis 0.4557209542137178 0.7694643343604528 0.4416177094475912 1.0 0.8811283339184687 10 O15067,P49915,P31939,P30520 4
Coenzyme a biosynthesis 0.7299940723177247 0.7690291336457481 0.4418760156502053 1.0 0.8811283339184687 2 Q9NVE7 1
Post translational modification synthesis of gpi anchored proteins 0.5235169869227363 0.7681471168834695 0.4423997873183904 1.0 0.8811283339184687 6 Q92643,Q96S52,Q9H490,Q9ULX3 4
Signaling by erbb4 0.4722623756182147 0.7592591719439813 0.4476975356468597 1.0 0.8811283339184687 8 Q92542,P46934,P61201 3
Reduction of cytosolic ca levels 0.7427946329173138 0.7577329975676778 0.4486108406815758 1.0 0.8811283339184687 3 P16615 1
Platelet calcium homeostasis 0.7427946329173138 0.7577329975676778 0.4486108406815758 1.0 0.8811283339184687 3 P16615 1
Metabolism of nucleotides 0.318341579301544 0.756930977526506 0.4490912153519937 1.0 0.8811283339184687 48 Q9H773,P49915,P00813 3
Oncogene induced senescence 0.4941214483949218 0.7448327285446646 0.4563728468104673 1.0 0.8820241961535535 7 P11802,Q9HCE1,P06400,Q00534 4
Cd28 co stimulation 0.4677941556575074 0.7365308266744293 0.4614077144250184 1.0 0.8820241961535535 8 P31751 1
Metabolism of carbohydrates 0.3141799171630896 0.7301973639558315 0.4652695536234741 1.0 0.8820241961535535 100 P11166,P15586,P30154,P06865,P08236,Q9BTX1,Q8NCH0,Q8TB61,P30153,Q9UBX3,P52789,P10253,P54802,Q9BRR6,P16278,Q7LGA3 16
Cytochrome p450 arranged by substrate type 0.7336065035035869 0.7256816334869557 0.4680339636823194 1.0 0.8820241961535535 3 Q16850 1
Dopamine neurotransmitter release cycle 0.7181387077652648 0.7246727758320388 0.4686528004738379 1.0 0.8820241961535535 2 O14936 1
Assembly of the hiv virion 0.6551467705234799 0.7243848643618218 0.4688294893948503 1.0 0.8820241961535535 4 A5D8V6 1
Traf6 mediated nf kb activation 0.5136475100110456 0.7240347364347677 0.4690444097075894 1.0 0.8820241961535535 6 P05067 1
Ptk6 regulates cell cycle 0.7178423236514532 0.723572753021946 0.4693280740652836 1.0 0.8820241961535535 2 P24941 1
Processing of smdt1 0.4330134380376472 0.7218073911703138 0.4704129046152285 1.0 0.8820241961535535 11 Q10713,Q8WWC4,Q8NE86,Q9BPX6 4
Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects 0.6524317912218304 0.7144124857672488 0.4749721535652924 1.0 0.885927484345376 4 P11802,P24941,P06400 3
Erk mapk targets 0.4451768743583885 0.7122578834231421 0.4763050991104172 1.0 0.885927484345376 10 P30154 1
Mapk targets nuclear events mediated by map kinases 0.4451768743583885 0.7122578834231421 0.4763050991104172 1.0 0.885927484345376 10 P30154 1
Activated notch1 transmits signal to the nucleus 0.7136929460580923 0.708220214388988 0.4788085148899963 1.0 0.8870356949157302 2 Q92542 1
Dag and ip3 signaling 0.4614648640579477 0.7044889193235992 0.4811283482268569 1.0 0.8887914933193855 8 O43865,Q13555,P10644 3
Translation of sars cov 1 structural proteins 0.4852631028263204 0.7028418611041648 0.4821543063178657 1.0 0.8887914933193855 7 P49841,Q10472 2
Negative regulation of nmda receptor mediated neuronal transmission 0.5056499999572812 0.6885882228109138 0.491082434497661 1.0 0.8978505846975585 6 Q14012,Q14168 2
Transport of bile salts and organic acids metal ions and amine compounds 0.6432454672837509 0.680890367818994 0.4959408633404458 1.0 0.9015148234874678 4 P35613,P53985 2
Post chaperonin tubulin folding pathway 0.4440154440154357 0.6586445444744995 0.510124051500386 1.0 0.9146300251971324 9 Q13885,Q15813,O75347,Q9BVA1,P68371,Q99426,Q9BUF5,P36404 8
Golgi cisternae pericentriolar stack reorganization 0.4126040428061742 0.6576697148831963 0.5107503868305134 1.0 0.9146300251971324 12 P62820,O95067,P53350,P61019,Q08379,Q9H8Y8,Q9H0U4,P06493,O60763,P27361,P14635 11
Class b 2 secretin family receptors 0.7123041312565812 0.652693736677223 0.5139537411551123 1.0 0.919010423573824 3 P63218 1
Mitochondrial biogenesis 0.3347567606057176 0.6273803397497402 0.5304099519030601 1.0 0.9242125384324064 34 P54619,P00846,Q13505,O75431,P24539,Q9NX63,Q9BUR5,Q9Y512,O75964 9
Suppression of apoptosis 0.6268406024381786 0.6219573612142772 0.5339699055475093 1.0 0.9253925235550764 4 P49840 1
Cilium assembly 0.2970554454236974 0.6217371814828511 0.5341146986444167 1.0 0.9253925235550764 68 O60645,Q13561,O94927,P41208,A0AVF1,O95684,Q9H6D7,P30153,O43805,Q15154,A6NIH7,O75935,Q9NV70 13
Visual phototransduction 0.4440432097034378 0.6173939045390354 0.5369749415447314 1.0 0.9253925235550764 8 P49356,P09455,Q6NUM9 3
Rnd3 gtpase cycle 0.3813198652200429 0.6173139109518627 0.5370276930440263 1.0 0.9253925235550764 16 Q13464,Q07065,Q8TAA9 3
Metabolism of steroid hormones 0.4891734612875253 0.6165604480741931 0.537524689373793 1.0 0.9253925235550764 6 Q14849 1
Innate immune system 0.3542828345023799 0.6058620378618553 0.5446063697465817 1.0 0.93103662475059 302 O43681,P10321,O15126,O43865,P25787,P08236,P28070,P07384,P09601,P05067,P30153,P04439,Q92542,O00264,Q99536,Q9UQB8,P30519,Q7L576,P27105,P04066,Q7Z434,P25786,Q9Y487,O15260,P28072,P10253,P06280,Q99538,Q9NZJ7,Q93050,O00560,Q13464,Q07065,P61289,P10619,Q969Q5,P30154,P15586,Q8WVQ1,Q9H7Z7,P61421,Q8IV08,Q9BRF8,Q14997,Q13685,P07602,Q8NF37,P16278,Q96F07,Q86UT6,P17900,P49721,P42785,P46108,Q9NQX7,P11279,Q13510,Q9BUI4,P20618,Q9UL46,P49720,O15121,Q92530,O00584 64
Nuclear signaling by erbb4 0.620494492382677 0.599514136802343 0.5488300858313984 1.0 0.9371088980842116 4 Q92542,P61201 2
Activation of nmda receptors and postsynaptic events 0.3535496919043237 0.5969471059658543 0.5505426957023936 1.0 0.9377375586139672 24 Q14012,P10644,P54619,O14936,P52292,P68371,Q13555,P51812,Q14168 9
Pre notch expression and processing 0.4097715048832308 0.5921893890204845 0.5537237740966825 1.0 0.9394910913241518 11 Q9UBV2,Q15363 2
Rhoj gtpase cycle 0.3525634074145552 0.5895381930734188 0.5555002992333424 1.0 0.9394910913241518 24 P27105,P42167,Q8TAA9,Q13153,P42166,Q15836,P02786 7
Protein protein interactions at synapses 0.3797059658332126 0.5892836683778078 0.5556709985949677 1.0 0.9394910913241518 15 Q14168,O95197 2
Organelle biogenesis and maintenance 0.3047849409905364 0.5828576198595355 0.5599891523041851 1.0 0.9394910913241518 102 O60645,Q13561,P00846,O75431,P30153,Q9NX63,Q9Y512,O75964,Q9NV70,P54619,P41208,O43805,Q15154,A6NIH7,O94927,Q13505,Q9BUR5,O75935,Q10713,A0AVF1,O95684,Q9H6D7,P24539 23
Ras processing 0.5216929775557306 0.5737765900706383 0.5661189921456795 1.0 0.9394910913241518 5 O60725 1
Synthesis of pips at the golgi membrane 0.4567550032442533 0.5705276002511787 0.5683199077658165 1.0 0.9394910913241518 7 Q9NTJ5,Q10713,Q9UBF8 3
Diseases of immune system 0.6733847065797285 0.5643648377202937 0.5725058637481681 1.0 0.9394910913241518 2 P09429 1
P75ntr signals via nf kb 0.6733847065797285 0.5643648377202937 0.5725058637481681 1.0 0.9394910913241518 2 Q13501 1
Nf kb is activated and signals survival 0.6733847065797285 0.5643648377202937 0.5725058637481681 1.0 0.9394910913241518 2 Q13501 1
Ddx58 ifih1 mediated induction of interferon alpha beta 0.3696556921097516 0.5618172679814026 0.5742405257051479 1.0 0.9394910913241518 17 Q86UT6,P05067 2
Anchoring of the basal body to the plasma membrane 0.3207429634752805 0.5617657606423727 0.5742756231417827 1.0 0.9394910913241518 37 Q13561,P41208,O95684,Q9H6D7,O43805,P30153,Q15154,O75935 8
Ephrin signaling 0.4754674542469404 0.5578637249453064 0.5769374437535906 1.0 0.9394910913241518 6 O00560 1
Basigin interactions 0.4539349955111219 0.5577239208676762 0.5770329205901863 1.0 0.9394910913241518 7 P35613,P53985 2
Arachidonic acid metabolism 0.4527179767164085 0.5522166016694683 0.5807999613475618 1.0 0.9394910913241518 7 Q15165,Q14914 2
Attachment of gpi anchor to upar 0.6067615658362956 0.5517041219921899 0.5811510853959936 1.0 0.9394910913241518 4 Q92643,Q9H490,Q96S52 3
Extra nuclear estrogen signaling 0.3849110806211463 0.5495758322209087 0.5826103389733119 1.0 0.9394910913241518 13 P31751 1
Transcriptional regulation by ventx 0.3931859549341425 0.5468261574362968 0.5844981706438193 1.0 0.9394910913241518 12 Q9HCE1,Q9UJX2,Q9UJX3,P19838,Q9UJX4,Q9UJX6,Q96DE5 7
Anti inflammatory response favouring leishmania parasite infection 0.3732332883872955 0.5347539685441691 0.5928199972371933 1.0 0.9394910913241518 14 O43865,P10644 2
Gene and protein expression by jak stat signaling after interleukin 12 stimulation 0.3447405599819656 0.5312052002412837 0.5952765897672108 1.0 0.9394910913241518 24 Q13126,O00170,Q9UL46,O14979,P78417,P52597 6
Transcription of e2f targets under negative control by p107 rbl1 and p130 rbl2 in complex with hdac1 0.6633076467101374 0.5301308226134744 0.5960212299798382 1.0 0.9394910913241518 2 Q13547 1
Late endosomal microautophagy 0.3961960671106703 0.5184392203635416 0.6041518562546202 1.0 0.9416668597488216 11 A5D8V6,P08670,Q9UQN3,Q9H9H4 4
Amino acid transport across the plasma membrane 0.5862504289883703 0.482463993662827 0.629476370696473 1.0 0.9467118622136224 4 P30825 1
Role of phospholipids in phagocytosis 0.6583643051288698 0.4783749135410518 0.6323833855217573 1.0 0.9467118622136224 3 Q8IV08 1
Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components 0.3875066733750739 0.4722059261026496 0.6367798102210653 1.0 0.9467118622136224 11 Q12834,Q9UJX6,Q9UJX3 3
Apc cdc20 mediated degradation of nek2a 0.3875066733750739 0.4722059261026496 0.6367798102210653 1.0 0.9467118622136224 11 Q12834,Q9UJX6,Q9UJX3 3
Cargo trafficking to the periciliary membrane 0.3425760362023133 0.4719001588894104 0.6369980546521683 1.0 0.9467118622136224 22 O60645,A6NIH7,Q9NV70 3
Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps 0.354863285854466 0.4673971586473738 0.6402157550831586 1.0 0.9467118622136224 17 O43852,Q07065,Q02818,P05067 4
Depolymerisation of the nuclear lamina 0.4058774306135088 0.4671130849196945 0.6404189729784662 1.0 0.9467118622136224 9 P50402,P42167 2
Ripk1 mediated regulated necrosis 0.3782069571683034 0.4638017987705677 0.6427897544911991 1.0 0.9467118622136224 12 Q16543,O75955 2
Interleukin 12 signaling 0.3284735927749985 0.4631859720020576 0.643231070436455 1.0 0.9467118622136224 26 Q13126,O00170,Q9UL46,O14979,P78417,P52597 6
Aurka activation by tpx2 0.3109460183821799 0.4612170277296969 0.6446429063218484 1.0 0.9467118622136224 36 Q13561,P41208,O95684,Q9H6D7,O43805,P30153,Q15154,O75935 8
Ra biosynthesis pathway 0.5795742854231338 0.4605522930353283 0.645119845657075 1.0 0.9467118622136224 4 Q8TC12,O94788 2
Diseases associated with n glycosylation of proteins 0.4914848330359734 0.4592265809407045 0.6460714643923788 1.0 0.9467118622136224 5 Q9BT22 1
Glutathione conjugation 0.3575669557172838 0.4533124678542944 0.6503237562448936 1.0 0.9483761462561192 15 P78417 1
Activation of nima kinases nek9 nek6 nek7 0.4897656481756236 0.4529198851270201 0.6506064315176388 1.0 0.9483761462561192 5 O95067,P06493,P53350,Q8TD19 4
Separation of sister chromatids 0.3003413630367248 0.439383522758585 0.6603836636810296 1.0 0.9517733627698344 111 P25787,P28070,P30153,Q15005,Q8WVM7,P28072,Q9BS16,P61289,P30154,Q92674,Q14997,Q8NBT2,Q7Z5K2,P49721,Q12834,P20618,Q9UL46,P49720,Q02224,Q9HBM1,Q92530 21
Dna damage recognition in gg ner 0.3499908681314593 0.4213857431744546 0.673473428043676 1.0 0.9567163259887252 16 P41208,Q9BT78 2
G beta gamma signalling through cdc42 0.475580891775251 0.4018883493569907 0.687766197388356 1.0 0.9675872311026832 5 P63218 1
Signaling by wnt 0.280731693547028 0.4014864245870567 0.6880620310063525 1.0 0.9675872311026832 88 P61289,P49721,Q9HCE1,P25786,P30154,P25787,P63218,P28070,P31751,P49841,P30153,P20618,Q14997,P49720,P28072,Q9UL46,Q9UBQ0,Q92530 18
Bile acid and bile salt metabolism 0.4725600711954998 0.3912647365800553 0.6956015615322684 1.0 0.974261223230436 5 Q96SU4,P22307,P22059,O14734 4
Synthesis of bile acids and bile salts 0.4725600711954998 0.3912647365800553 0.6956015615322684 1.0 0.974261223230436 5 Q96SU4,P22307,P22059,O14734 4
G protein beta gamma signalling 0.4146523544787361 0.3866273881261872 0.6990320790038347 1.0 0.9780840022170004 7 P31751,P63218 2
Ncam signaling for neurite out growth 0.4119916889284624 0.3756204295529355 0.707199100577907 1.0 0.9805353693621514 7 Q01082,P62993,Q13813,O15020,Q05397,P27361 6
G2 m checkpoints 0.2816236656098206 0.3727820682532 0.7093106498914108 1.0 0.9805353693621514 92 P25787,Q04917,P28070,P62258,Q9NWV8,Q9Y619,P33991,Q14566,P24941,P25786,O96028,P28072,P60900,P28074,P35250,Q99640,P61289,O00231,Q9NXR7,P33993,Q14997,Q14191,O60921,P40937,P49721,P20618,Q9UL46,P49720,P49736,Q92530 30
G beta gamma signalling through pi3kgamma 0.5496673454422656 0.3667349809153741 0.7138167108630726 1.0 0.9813934837694036 4 P31751 1
Fcgr3a mediated il10 synthesis 0.4256513759273149 0.3574431935954624 0.7207600457766408 1.0 0.983816305145219 6 P10644 1
Dna replication 0.2808617616797765 0.3529564762289453 0.7241210701100362 1.0 0.9844622653486236 93 P25787,P28070,Q9NR33,Q9UJX6,Q96DE5,Q9Y619,P33991,Q14566,P24941,P25786,P28072,P28074,P35250,P49643,P61289,O00231,Q9UJX3,P33993,Q14997,P40937,P49005,P49721,P56282,P20618,Q9UL46,P49720,P49736,Q92530 28
Nuclear events kinase and transcription factor activation 0.3499826145117346 0.3529356306932532 0.7241366980916211 1.0 0.9844622653486236 13 P30154 1
Diseases of mitotic cell cycle 0.3493838504148423 0.3497230368789979 0.7265465631960986 1.0 0.9844622653486236 13 P24941,Q9UJX2,Q9UJX3,Q9UJX4,Q9UJX6,Q00534,Q96DE5,P11802,P06400 9
Copi independent golgi to er retrograde traffic 0.3093689917991782 0.3418222304766285 0.7324846787177268 1.0 0.9851077726263996 29 P47756,Q13561,Q8TD16,P52907,P68402,Q9H2M9,P68371,O75935,Q9UJW0,P61163,Q10472,Q9Y6G9 12
Raf activation 0.360869746198282 0.336508380030039 0.7364875333220344 1.0 0.9851077726263996 11 P30154,P30153 2
Signal amplification 0.3831522794996036 0.333001318350635 0.7391332879978751 1.0 0.9851077726263996 8 P63218 1
Phosphorylation of the apc c 0.3598632824270373 0.3315902431148667 0.7401986880058007 1.0 0.9851077726263996 11 Q9UJX2,Q9UJX3,Q9UJX4,P06493,Q9UJX6,Q96DE5 6
Plasma lipoprotein clearance 0.3420298457509158 0.3107952376400534 0.7559562903369252 1.0 0.9856042026196724 13 Q8WTV0 1
Nr1h2 nr1h3 regulate gene expression linked to lipogenesis 0.5892116182572629 0.3065875494143052 0.7591573316704305 1.0 0.9856042026196724 2 P49327 1
Toll like receptor tlr1 tlr2 cascade 0.3214888128060569 0.3045820304676725 0.7606845077295983 1.0 0.9856042026196724 20 P30154,P05067 2
Inhibition of replication initiation of damaged dna by rb1 e2f1 0.393349464609392 0.3010427952001002 0.7633818614053998 1.0 0.9857148173093284 7 P30154,P30153 2
Miro gtpase cycle 0.4452684663304751 0.2996622078656815 0.7644348282813187 1.0 0.9857148173093284 5 P52306,Q8IWA4,Q8IXI1,O95140 4
Cardiac conduction 0.3463186481860107 0.2972363444679862 0.7662860761588284 1.0 0.9857148173093284 12 Q13555,O43865,P16615,P05023 4
Carboxyterminal post translational modifications of tubulin 0.439335508751121 0.2808869832862278 0.778797084734846 1.0 0.994464368167106 5 Q9BVA1,Q13885,Q9BUF5,P68371 4
Interferon alpha beta signaling 0.3666689849142277 0.2639685112649333 0.7918041827729705 1.0 1.0 8 P04439 1
Toll like receptor cascades 0.2981936637529639 0.2590682505164311 0.7955825811164043 1.0 1.0 29 Q99538,P30154,P05067 3
Signaling by retinoic acid 0.3365659576798315 0.2498472134832881 0.8027055062396693 1.0 1.0 12 P50416,Q8TC12,P11177,O94788 4
Gap junction assembly 0.5047449584816001 0.2416890523503758 0.8090211130806644 1.0 1.0 4 Q13885,Q9BUF5,P68371 3
Transport of connexons to the plasma membrane 0.5047449584816001 0.2416890523503758 0.8090211130806644 1.0 1.0 4 Q13885,Q9BUF5,P68371 3
Serine biosynthesis 0.5706296300897156 0.2416602236195735 0.8090434530588948 1.0 1.0 3 P78330 1
Activation of atr in response to replication stress 0.3044302496893634 0.233230157789385 0.8155826889665254 1.0 1.0 23 O60921,P40937,Q14566,P24941,P33993,P33991,P49736,Q9UBD5,Q9Y619,P35250 10
Muscle contraction 0.2959180834588112 0.231641195167304 0.816816708482222 1.0 1.0 27 O43865,P05023,P20020,P08670,P04083,Q13153,Q13555,P60660,P16615 9
Adenylate cyclase inhibitory pathway 0.5591461606878239 0.21621748511501 0.8288182247425833 1.0 1.0 3 P04899,P08754 2
Neuronal system 0.2671998941586709 0.2130262963488832 0.8313064518850823 1.0 1.0 53 Q14012,P10644,P63218,O75915,Q13555,Q14168,O95197,P21964,O75955 9
Cohesin loading onto chromatin 0.3430104347647049 0.210540757783099 0.8332456443535692 1.0 1.0 10 Q9Y6X3,Q7Z5K2 2
Golgi associated vesicle biogenesis 0.2875614337777883 0.1981288764681849 0.8429442324912624 1.0 1.0 31 Q9BXS5,P11717,Q9Y5X3,O14976,P55327,Q9H3P7,O60749,Q99523,O75976,P02786 10
Plasma lipoprotein assembly remodeling and clearance 0.310119292276763 0.1960638933485379 0.8445601566636762 1.0 1.0 16 Q8WTV0 1
Peroxisomal lipid metabolism 0.3173112425314544 0.1881696948979792 0.8507436280801812 1.0 1.0 13 O14734,P51648 2
Insulin processing 0.3423225653470936 0.1870992326343961 0.8515828298042472 1.0 1.0 9 O60645 1
E3 ubiquitin ligases ubiquitinate target proteins 0.30557724624893 0.1807535958732606 0.8565609881665968 1.0 1.0 17 P04439,P50542 2
Nuclear receptor transcription pathway 0.529934795494963 0.1727079548410954 0.8628809907000856 1.0 1.0 2 O75376 1
Cooperation of prefoldin and tric cct in actin and tubulin folding 0.3021579830431737 0.1723842886157707 0.8631354231497672 1.0 1.0 18 Q99471,P68371,P78371,O15212,P61758,Q99832,Q9UHV9,O60925 8
Grb2 sos provides linkage to mapk signaling for integrins 0.5348354580492216 0.167195550671351 0.8672161851937938 1.0 1.0 3 Q05397,Q9Y490 2
Long term potentiation 0.3971037675210092 0.1609459719146909 0.872135953902464 1.0 1.0 5 Q14168 1
Unblocking of nmda receptors glutamate binding and activation 0.3971037675210092 0.1609459719146909 0.872135953902464 1.0 1.0 5 Q14168 1
Ras activation upon ca2 influx through nmda receptor 0.3971037675210092 0.1609459719146909 0.872135953902464 1.0 1.0 5 Q14168 1
Assembly and cell surface presentation of nmda receptors 0.3301475046962207 0.1588963126138824 0.8737505658950253 1.0 1.0 10 Q14168,Q13555,P68371,O14936 4
Creb phosphorylation 0.5198577356253721 0.1544946058860544 0.8772197640389459 1.0 1.0 2 P51812 1
Regulation of plk1 activity at g2 m transition 0.2689560449798369 0.1539565099763697 0.877644026675491 1.0 1.0 41 Q13561,P41208,O95684,Q9H6D7,O43805,P30153,Q15154,O75935 8
Ptk6 regulates rho gtpases ras gtpase and map kinases 0.3927897477427544 0.1501659819337372 0.8806336640059618 1.0 1.0 5 P46108 1
Dscam interactions 0.4644128113878924 0.149013111795991 0.8815432867631259 1.0 1.0 4 Q16539,Q13153,Q16512 3
Trna modification in the nucleus and cytosol 0.3013983933353212 0.1464980289856418 0.8835282457746905 1.0 1.0 15 Q9NPF4,Q9BXR0,Q9UET6,Q9UI30,Q7Z4G4,Q9UBP6,P07814,O75648,Q6YHU6,Q5VV42,Q9H974,Q08J23,Q96FX7,Q9Y606 14
Interleukin 12 family signaling 0.2816172392959805 0.1440406261095448 0.8854683891266677 1.0 1.0 29 Q13126,O00170,P14174,Q9UL46,O14979,P78417,P52597 7
Nr1h2 and nr1h3 mediated signaling 0.3598843579316042 0.139914934716057 0.8887272011653291 1.0 1.0 6 Q9HCE1 1
Binding and uptake of ligands by scavenger receptors 0.3471818128935667 0.1396481391531961 0.8889380037100574 1.0 1.0 7 Q8WTV0 1
Activation of bad and translocation to mitochondria 0.3323757822027132 0.1359119553069043 0.8918908842100235 1.0 1.0 8 Q04917,P31751,P62258,P31946,P27348 5
Transcriptional regulation by runx1 0.2547847056647827 0.1337774117845996 0.8935785894052775 1.0 1.0 70 P17931,P61289,Q9HCE1,P49721,P25786,P25787,P28070,O00231,Q9UL46,Q14997,P20618,P28072,Q9HCL2,P49720,P28074,Q92530 16
Alpha linolenic omega3 and linoleic omega6 acid metabolism 0.3439242796680765 0.1297282175588027 0.8967814568296548 1.0 1.0 7 O14734,Q15067 2
Sars cov 1 infection 0.2976994559964089 0.1290335265652556 0.8973311202102909 1.0 1.0 15 P49841,Q10472 2
Signaling by erbb2 0.3212339416995838 0.1253078502859137 0.900279837542642 1.0 1.0 10 P31751 1
Lipophagy 0.50860795840878 0.1219206267703747 0.902961879692238 1.0 1.0 3 P54619 1
Egfr downregulation 0.3377856930840063 0.1116157731988732 0.9111280649704814 1.0 1.0 7 P62993,O14964,Q14155,Q99961,Q92783,P42566 6
Activation of smo 0.4922940130409025 0.1115233044708955 0.911201386572869 1.0 1.0 2 P48729 1
Fcgamma receptor fcgr dependent phagocytosis 0.2682437600209952 0.1114229885641183 0.911280931325554 1.0 1.0 36 Q7L576,O43865,Q96JJ3,P46108,Q8IZP0,Q8IV08,Q96F07,Q9UQB8 8
Toll like receptor 9 tlr9 cascade 0.2845959394228187 0.1062588259249275 0.9153769987353876 1.0 1.0 22 P30154,P05067 2
Lysosome vesicle biogenesis 0.2874584491224135 0.0911772395168129 0.9273517598451796 1.0 1.0 17 P15586,P05067 2
Energy dependent regulation of mtor by lkb1 ampk 0.3388724035608372 0.0856842574047354 0.931717416870414 1.0 1.0 6 Q6IAA8,Q9Y2Q5,P54619,P42345,Q13131 5
Cd28 dependent vav1 pathway 0.3376854599406611 0.0828699678395352 0.9339549340717088 1.0 1.0 6 P62993,Q13153,P63000,Q13177,Q16512 5
Myd88 independent tlr4 cascade 0.2788100470628757 0.0827614376076728 0.9340412322246768 1.0 1.0 23 P30154,P05067 2
Activated ntrk2 signals through cdk5 0.4641375222288103 0.0776099549488255 0.9381383233650122 1.0 1.0 2 Q00535 1
Syndecan interactions 0.3589254439139575 0.0758991667925613 0.9394993197523398 1.0 1.0 5 P12814,O14936 2
Thromboxane signalling through tp receptor 0.4211267770275319 0.0727842337990829 0.941977817283042 1.0 1.0 4 P63218 1
Mitotic metaphase and anaphase 0.2922198366276189 0.0688767768033647 0.945087704036376 1.0 1.0 145 P25787,P28070,Q8N1F7,P30153,Q15005,P50402,Q8WVM7,Q9BTX1,Q14739,P28072,Q9BS16,P61289,P30154,Q92674,Q14997,Q8NBT2,Q86XL3,Q7Z5K2,P49721,Q12834,P42167,P20618,Q9UL46,P49720,Q02224,Q9HBM1,Q92530 27
Regulation of innate immune responses to cytosolic dna 0.4653981152329874 0.0645771639618932 0.9485106672682472 1.0 1.0 3 Q9UJV9 1
Myoclonic epilepsy of lafora 0.4478363959691779 0.0622414108245823 0.9503705853300184 1.0 1.0 2 P13807 1
Sema3a plexin repulsion signaling by inhibiting integrin adhesion 0.4630892380670094 0.0620962752003198 0.9504861632355052 1.0 1.0 3 P63000,Q9Y490 2
Rhot1 gtpase cycle 0.4448725548310628 0.0597585491191915 0.9523479395549008 1.0 1.0 2 P52306 1
Mitotic telophase cytokinesis 0.2870272843707078 0.0594064773782929 0.9526283539715632 1.0 1.0 13 Q9Y6X3,Q7Z5K2 2
Rsk activation 0.4116251482799505 0.0593397736135097 0.9526814821501676 1.0 1.0 4 P27361,P51812,Q15418 3
Negative feedback regulation of mapk pathway 0.4116251482799337 0.0593397736134866 0.952681482150186 1.0 1.0 4 P36507,P27361,Q02750 3
Irf3 mediated activation of type 1 ifn 0.4410195613515132 0.0566676855210176 0.9548099158529462 1.0 1.0 2 Q9UHD2 1
Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux 0.4074270827222443 0.0537694575929621 0.9571188436139346 1.0 1.0 4 Q9HCE1 1
Free fatty acids regulate insulin secretion 0.4368701837581521 0.053508014604177 0.9573271450684696 1.0 1.0 2 O60488 1
Zbp1 dai mediated induction of type i ifns 0.3429249480866288 0.0473645360465229 0.9622226934170752 1.0 1.0 5 Q9UHD2,Q13546,Q9NZI8,P19838 4
Runx2 regulates bone development 0.3423316523286931 0.0463876664479409 0.9630012666803702 1.0 1.0 5 P27361,P28482,Q96PK6,P06400 4
Aspartate and asparagine metabolism 0.3409606411959398 0.044152356411029 0.9647829590642174 1.0 1.0 5 P08243,Q9UJS0 2
Signaling by nodal 0.4113811499703635 0.0376437338593048 0.9699717380383864 1.0 1.0 2 P27361 1
Signaling by activin 0.4113811499703635 0.0376437338593048 0.9699717380383864 1.0 1.0 2 P27361 1
Deactivation of the beta catenin transactivating complex 0.2972007800151931 0.0364406228231948 0.970931023346698 1.0 1.0 9 P31751,Q9UBL3 2
Uptake and function of diphtheria toxin 0.3881969157769812 0.0310716856011209 0.975212370379615 1.0 1.0 4 Q16881,P07900,P08238 3
Creb1 phosphorylation through nmda receptor mediated activation of ras signaling 0.2952179664221439 0.0309731157220694 0.97529097992864 1.0 1.0 9 Q14168 1
Ticam1 rip1 mediated ikk complex recruitment 0.3953764078245425 0.0304229803184409 0.9757297176926184 1.0 1.0 2 Q13546 1
Phenylalanine and tyrosine metabolism 0.3310590329279226 0.0289176998050064 0.9769302291217994 1.0 1.0 5 P09417,O43708,P16930,P61457 4
Uptake and function of anthrax toxins 0.4201008004743568 0.025664426721867 0.9795249978684716 1.0 1.0 3 P36507,Q8WUM4 2
Wax and plasmalogen biosynthesis 0.3825622775800591 0.0252697356963829 0.9798398136350136 1.0 1.0 4 O00116,O15228,Q6IAN0 3
Vxpx cargo targeting to cilium 0.2896291997573533 0.0223961164956586 0.982131978163692 1.0 1.0 10 O60645 1
Signal attenuation 0.4115031129558295 0.0203992531664072 0.9837248796141412 1.0 1.0 3 P27361,P62993 2
Activation of the ap 1 family of transcription factors 0.4115031129558285 0.0203992531664069 0.9837248796141412 1.0 1.0 3 Q16539,P27361 2
Glycolysis 0.2438943635390913 0.017384790139896 0.9861296430332416 1.0 1.0 48 Q9BRR6,Q9BTX1,P30154,P30153 4
Neurotransmitter release cycle 0.3044712819559148 0.0152314763722643 0.987847510058122 1.0 1.0 6 O75915,O14936 2
Glutamate neurotransmitter release cycle 0.3931905213291767 0.0110971282850446 0.9911459543962484 1.0 1.0 3 O75915 1
Sema3a pak dependent axon repulsion 0.293855743544082 0.0054014617764274 0.995690277999422 1.0 1.0 7 Q13153,P08238,P63000,P07900,Q13177,Q16512 6
Mtorc1 mediated signalling 0.2852881652690745 0.0051426544657001 0.9958967734865488 1.0 1.0 9 P06730 1
Slc transporter disorders 0.2572068797604689 0.0051411524710255 0.9958979718890676 1.0 1.0 32 P35613,P11166,P53985,Q9BTX1,Q8N1F7 5
Activation of irf3 irf7 mediated by tbk1 ikk epsilon 0.3723144214081071 0.0032542491182982 0.9974034894544048 1.0 1.0 3 Q6SZW1 1