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Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
Acquired partial lipodystrophy barraquersimons syndrome 0.9266287017280248 2.4970978016598857 0.0125214417028736 0.9995171962535888 1.0 5 O60725 1
Sphingolipid metabolism integrated pathway 0.8913245465973061 2.454053937495664 0.0141255792176551 0.999819744386057 1.0 9 Q96G23,O15121,Q06136,Q13510,Q16739,O95470 6
Sphingolipid metabolism overview 0.8913245465973061 2.454053937495664 0.0141255792176551 0.999819744386057 1.0 9 Q96G23,O15121,Q06136,Q13510,Q16739,O95470 6
Sphingolipid pathway 0.8867571403438197 2.434843296177316 0.0148982401162518 0.9998879160230462 1.0 9 Q96G23,Q06136,P04062,Q13510,Q16739 5
Cholesterol biosynthesis with skeletal dysplasias 0.8420101845148427 2.3047702699180403 0.0211794429896454 0.9999976769019524 1.0 6 Q14739,Q9UBM7,Q15392 3
Glycosaminoglycan degradation 0.8667723383925157 2.2517281096618165 0.0243394591591599 0.9999996726314078 1.0 5 P06865,P54802,P16278 3
Familial partial lipodystrophy fpld 0.8346857387007289 2.2327996744429455 0.0255621577717855 0.9999998468878354 1.0 8 O75844,O60725 2
Metabolism of spingolipids in er and golgi apparatus 0.8951981152394051 2.2295930772871917 0.0257744698577213 0.999999865828328 1.0 4 Q06136,Q16739 2
Sphingolipid metabolism in senescence 0.8460146043924957 2.2019968515515886 0.0276655308684259 0.9999999586664112 1.0 12 Q96G23,O15121,P04062,Q13510,Q16739,P16278 6
Progeriaassociated lipodystrophy 0.8365469742565398 2.2008125010663524 0.0277493002350532 0.9999999607691042 1.0 10 O75844,O60725 2
Vitamin d metabolism 0.9473027751792928 1.9380972957780171 0.0526113533286611 0.999999999999994 1.0 3 P04062,P38435 2
Degradation pathway of sphingolipids including diseases 0.758650937989485 1.9186262723379044 0.0550316482195152 0.9999999999999988 1.0 7 P06865,P16278,P06280,P17900 4
Photodynamic therapyinduced nfe2l2 nrf2 survival signaling 0.7742429053872246 1.8593583441156327 0.0629763621295125 1.0 1.0 5 P07099 1
Neuroinflammation 0.7588535064761982 1.792656464387632 0.0730278718317642 1.0 1.0 5 P42345,O15111,P00403 3
Kennedy pathway from sphingolipids 0.7531029191119089 1.767635329464866 0.0771218877679928 1.0 1.0 5 O95470,P48651,Q9UG56 3
Oxidation by cytochrome p450 0.7509285999075391 1.7581614456710994 0.078720043195207 1.0 1.0 5 Q16850,O43169,Q6UW02 3
Influence of laminopathies on wnt signaling 0.7398639088021413 1.7539997655423385 0.0794305473201926 1.0 1.0 11 O75844,P49354,P50402,O60725 4
15q112 copy number variation syndrome 0.7698066126013879 1.7107345004913188 0.0871301357630358 1.0 1.0 4 Q9BSJ2,Q7L576,Q96CW5 3
Nocgmppkg mediated neuroprotection 0.7117906169173331 1.7067277642999437 0.087872664194611 1.0 1.0 7 P07196,P30536 2
Triacylglyceride synthesis 0.7350686015048475 1.688843331630784 0.0912494573974653 1.0 1.0 5 O00116,Q9NUQ2 2
Eicosanoid metabolism via lipooxygenases lox 0.7068071805920437 1.6839513999488012 0.0921910615629486 1.0 1.0 7 Q08426,Q15067,P09960 3
Constitutive androstane receptor pathway 0.6979146890295127 1.6634503288859197 0.0962223257895997 1.0 1.0 6 P08183 1
Statin inhibition of cholesterol production 0.698978818272264 1.6480848299520492 0.0993352648275756 1.0 1.0 7 P35610,Q8WTV0,P37268 3
Proteoglycan biosynthesis 0.7407906001918366 1.58757928327473 0.1123815058555448 1.0 1.0 4 Q8NCH0 1
Overlap between signal transduction pathways contributing to lmna laminopathies 0.7058792780886247 1.5025301436144889 0.1329602491128096 1.0 1.0 16 P49354,P55209,O60725,P50402,P48729,P42166,O75844 7
Methionine de novo and salvage pathway 0.6746914348118087 1.4764097979451656 0.1398339140027631 1.0 1.0 10 Q99707,Q13126 2
Omega3 omega6 fatty acid synthesis 0.6552448008667049 1.4659968492028963 0.1426491452362066 1.0 1.0 6 Q15067 1
Insulin signaling in adipocytes normal condition 0.7064878353088033 1.4409698366621695 0.1495932045004502 1.0 1.0 4 P62753,P42345,P31751 3
Insulin signaling in adipocytes diabetic condition 0.7064878353088033 1.4409698366621695 0.1495932045004502 1.0 1.0 4 P62753,P42345,P31751 3
T cell receptor and costimulatory signaling 0.6847897766645048 1.3478699828776797 0.1777002041000499 1.0 1.0 4 P49840 1
Ovarian infertility 0.7901416155008647 1.3417113945132 0.1796895910311948 1.0 1.0 3 O75376 1
Eicosanoid metabolism via cyclooxygenases cox 0.6285800302465329 1.3214569721763445 0.1863490403755818 1.0 1.0 7 Q08426,Q15067 2
Ketogenesis and ketolysis 0.6218388498381444 1.3097240972885915 0.1902891885585957 1.0 1.0 6 P53985,O43772,P35610 3
Praderwilli and angelman syndrome 0.6295972404558599 1.3064544481046267 0.1913980601205782 1.0 1.0 8 Q15154,Q7L576 2
Eicosanoid synthesis 0.7633302151543716 1.2389555293425678 0.2153619674857307 1.0 1.0 3 Q9H7Z7,P09960 2
Sarscov2 and covid19 pathway 0.7520809915922667 1.1959117795335206 0.2317309878347693 1.0 1.0 3 Q8WTV0 1
Allograft rejection 0.603276705591183 1.1639440213583934 0.2444466981226269 1.0 1.0 9 P04439,P42574,P08183 3
Erk pathway in huntingtons disease 0.7424384159650896 1.1590749203137598 0.2464256477177491 1.0 1.0 3 P42858,P42574 2
Cholesterol metabolism with bloch and kandutschrussell pathways 0.6507112941160388 1.086153531170618 0.2774110722218375 1.0 1.0 25 Q15800,Q15392,P35610,O00767,Q9UBM7,Q14739,Q9BWD1,P48449 8
7oxoc and 7betahc pathways 0.5660443843705741 0.990253689244834 0.3220501361858012 1.0 1.0 9 O15118,P61916 2
Il10 antiinflammatory signaling pathway 0.5719896180551123 0.9647985234342712 0.3346457356487406 1.0 1.0 5 P09601 1
Sting pathway in kawasakilike disease and covid19 0.6889045795418686 0.9564077149717836 0.3388662884732283 1.0 1.0 3 Q86UT6 1
Vitamin d receptor pathway 0.5606032549710539 0.9463756003361335 0.343957045853946 1.0 1.0 10 P33897,P04080,Q96KA5,P09493,Q92604,P08183 6
Supression of hmgb1 mediated inflammation by thbd 0.6803879605301102 0.924603162849307 0.3551723672341478 1.0 1.0 3 P09429 1
Angiotensin ii receptor type 1 pathway 0.672092007391097 0.8937826676828926 0.3714381844504304 1.0 1.0 3 P63244 1
Histone modifications 0.545093613807206 0.8931421635257306 0.371781045997106 1.0 1.0 9 Q03164 1
Pregnane x receptor pathway 0.5530558937902204 0.8817221731082328 0.3779270673087183 1.0 1.0 5 P08183 1
Mitochondrial complex iv assembly 0.5541167121920254 0.8442082409734843 0.3985530502741317 1.0 1.0 14 Q9Y241,P14406,P20674,Q9Y2R0,P14854 5
Vitamin dsensitive calcium signaling in depression 0.5266932806922273 0.8266639140733264 0.4084275801071877 1.0 1.0 8 Q8NB78 1
Nuclear receptors in lipid metabolism and toxicity 0.8279301745635934 0.8237169088985361 0.4101004294803854 1.0 1.0 2 P08183 1
Exrna mechanism of action and biogenesis 0.6507639538509642 0.8153985730517974 0.4148442008728628 1.0 1.0 3 Q9HAV4,Q8WYQ5 2
Hostpathogen interaction of human coronaviruses autophagy 0.5374326638356552 0.8139194054365669 0.4156911230151716 1.0 1.0 5 P42345 1
Metastatic brain tumor 0.6485812285625165 0.8074551323079178 0.4194043143343275 1.0 1.0 3 P04637,P60953 2
Drug induction of bile acid pathway 0.8188902743142171 0.7931689012977818 0.4276794236788066 1.0 1.0 2 P08183 1
Methionine metabolism leading to sulfur amino acids and related disorders 0.5272527657673565 0.7702030350834357 0.4411794638184632 1.0 1.0 5 Q99707 1
Vitamin b12 metabolism 0.5121652301417399 0.7602661171049426 0.4470955308431332 1.0 1.0 8 Q8WTV0 1
Copper homeostasis 0.5154540031486065 0.7574611634357654 0.448773624662099 1.0 1.0 9 P78536,P05067,P42574 3
Disorders of folate metabolism and transport 0.5103531985716182 0.7520355960011607 0.4520296526743166 1.0 1.0 8 Q99707,P04818 2
Metapathway biotransformation phase i and ii 0.5507167251239332 0.7095295637865634 0.4779959120671577 1.0 1.0 21 Q86UY6,Q6UW02,Q8NCH0,P07099,Q16850 5
Mir517 relationship with arcn1 and usp1 0.7914588528678328 0.7022740696351735 0.4825082610439206 1.0 1.0 2 O94782 1
Mammary gland development pathway pregnancy and lactation stage 3 of 4 0.4882017609558071 0.6697245275672911 0.5030334129848064 1.0 1.0 7 P25490,O15111 2
Fibrin complement receptor 3 signaling pathway 0.605238525329565 0.6535706731474232 0.513388443542599 1.0 1.0 3 O15111 1
Hematopoietic stem cell gene regulation by gabp alphabeta complex 0.5190138062660554 0.6535311001128873 0.5134139464435088 1.0 1.0 4 Q15554 1
Adipogenesis 0.5119732004132804 0.6233408139746884 0.5330605825998433 1.0 1.0 16 O75844,O75376,O00767,P43490 4
Intracellular trafficking proteins involved in cmt neuropathy 0.4646860008896255 0.5827361043610568 0.5600709643399968 1.0 1.0 6 Q9NR77,P07196 2
Pyrimidine metabolism and related diseases 0.4745634926003388 0.5760752567425992 0.5645643150971007 1.0 1.0 9 Q9H0P0,P31350,Q02127,P23921,P04818 5
Regucalcin in proximal tubule epithelial kidney cells 0.4601752139276389 0.5631065915138783 0.5733623033133517 1.0 1.0 6 P42574,P42345 2
Bladder cancer 0.4951106757449405 0.5620445430264789 0.5740856711363049 1.0 1.0 4 P28482,P11802 2
Mapk and nfkb signaling pathways inhibited by yersinia yopj 0.5772462925059705 0.5591358225929359 0.5760690284068606 1.0 1.0 3 O15111 1
Mitochondrial complex iii assembly 0.4624922189665925 0.5244364765372663 0.599974991520229 1.0 1.0 9 P22695,Q6DKK2,O14949,Q9UDW1 4
Map3k1 role in promoting and blocking gonadal determination 0.4489889213608434 0.5150681216573612 0.6065054180512306 1.0 1.0 6 P61586,P28482,Q9Y6R4 3
Cholesterol biosynthesis pathway 0.4755403781084734 0.500931262882134 0.61641949944565 1.0 1.0 14 Q15800,Q9UBM7,P48449,P37268,Q16850 5
Ethanol effects on histone modifications 0.4559597455111486 0.4969543993937778 0.6192212085304805 1.0 1.0 9 Q99707,P04818 2
Type ii diabetes mellitus 0.5564524438019051 0.4922437504007083 0.6225470393568815 1.0 1.0 3 P42345 1
Cardiac progenitor differentiation 0.7216334164588565 0.4871166510018958 0.6261756671019898 1.0 1.0 2 Q16539 1
Mirna regulation of p53 pathway in prostate cancer 0.4733583405415767 0.4826908017610378 0.6293152953169947 1.0 1.0 4 P42574 1
Biomarkers for pyrimidine metabolism disorders 0.4512945373784169 0.4775453470459773 0.6329738378796446 1.0 1.0 9 Q9H0P0,P31350,Q02127,P23921,P04818 5
Endothelin pathways 0.4461844104159863 0.4718270145158928 0.6370502668546929 1.0 1.0 8 P00403,P16615,P42892 3
Striated muscle contraction pathway 0.4322439390507081 0.445102551684621 0.6562456448837799 1.0 1.0 6 P06753,P09493 2
Nephrotic syndrome 0.4585002540449333 0.4172421159662234 0.676501322604206 1.0 1.0 15 O75844,Q14108 2
Robo4 and vegf signaling pathways crosstalk 0.6963840399002535 0.4168263809238406 0.6768054047858454 1.0 1.0 2 P63000 1
Valproic acid pathway 0.4248004630254914 0.4000733208713602 0.6891025137961471 1.0 1.0 7 Q08426 1
Spinal cord injury 0.4523399439713861 0.3654485439449772 0.7147766104056323 1.0 1.0 17 P63000,P60953,P06493,Q9NQC3,P08670,P27695,P04637,P11802,P61586,P28482,P42574,P04083 12
H19 action rbe2f1 signaling and cdkbetacatenin activity 0.4242175549600259 0.3649547310296842 0.7151451983182491 1.0 1.0 5 P11802 1
Wnt signaling pathway 0.441281537233462 0.3646542692549132 0.7153694991215516 1.0 1.0 14 P63000,P49840,P42345,P48729,Q9BTU6,P61586,P28482,Q13363 8
Immune response to tuberculosis 0.4369870782233782 0.3605255514033893 0.7184541522722256 1.0 1.0 4 P15260 1
Proximal tubule transport 0.4256188442920865 0.3603601485511486 0.7185778243030896 1.0 1.0 10 P08183,P05023 2
Mitochondrial long chain fatty acid betaoxidation 0.4340388890320819 0.3509460715438069 0.7256288068638497 1.0 1.0 13 O43772,Q08426,P23786,P49748 4
Glycerophospholipid biosynthetic pathway 0.4097609636622131 0.3278704933381383 0.7430095845219389 1.0 1.0 8 P48651,O00116,Q9HCL2 3
Tolllike receptor signaling related to myd88 0.4162461999935729 0.2979841220764881 0.7657152821898843 1.0 1.0 4 O15111 1
Monoamine transport 0.4877213534431717 0.2972692389819961 0.766260964432218 1.0 1.0 3 O15127 1
Sterol regulatory elementbinding proteins srebp signaling 0.4779371118174552 0.2912337905797416 0.7708725209345326 1.0 1.0 30 O95486,Q14534,Q9HCL2,P49840,O00767,P42345,Q16850,P37268,P25490,O94979,Q8WTV0,P48449 12
Mitochondrial complex ii assembly 0.6449501246882843 0.2896122924394205 0.7721128618521598 1.0 1.0 2 P21912 1
S1p receptor signal transduction 0.3973624834672227 0.2824937777795681 0.7775649169935726 1.0 1.0 8 Q9H0H5,Q13510 2
Estrogen receptor pathway 0.4815232780624651 0.2820472788674115 0.7779072579804707 1.0 1.0 3 Q15067 1
Hostpathogen interaction of human coronaviruses apoptosis 0.4086722572817949 0.2766114085420718 0.7820785036474787 1.0 1.0 4 P42574 1
Mirna biogenesis 0.4055549883677689 0.2680547849248163 0.7886571489316188 1.0 1.0 4 Q9HAV4,Q8WYQ5 2
Apoptosis modulation by hsp70 0.384282850364802 0.2616602558046774 0.7935833844502658 1.0 1.0 6 O95831,P42574,P49327 3
Pentose phosphate pathway in senescent cells 0.3875195007800258 0.2474661023532861 0.8045475221936891 1.0 1.0 5 P29401,O95336,P04637,P37837 4
Phase i biotransformations non p450 0.4605088169064266 0.2337712155868265 0.8151625970828198 1.0 1.0 3 Q15165 1
Angiogenesis 0.4565679904937924 0.2253102424298605 0.8217379322050462 1.0 1.0 3 Q16539 1
Reninangiotensinaldosterone system raas 0.4558777673838364 0.2238480222737886 0.8228755615838204 1.0 1.0 3 Q14571,Q13555 2
Burn wound healing 0.3766811631922387 0.2003171649932518 0.8412325388862754 1.0 1.0 9 P09429,P42574,P31949 3
Microglia pathogen phagocytosis pathway 0.3749220212102363 0.191832692636955 0.8478732615049032 1.0 1.0 4 P63000,O00443,P07948 3
Nitric oxide metabolism in cystic fibrosis 0.3739862757329991 0.1897374328221662 0.8495148864365767 1.0 1.0 4 Q86X55,Q99873,O14744 3
Head and neck squamous cell carcinoma 0.3789092153503777 0.1743048355796459 0.8616258991756904 1.0 1.0 12 P62753,P11802,P31751 3
3q29 copy number variation syndrome 0.3788010853562617 0.1739767741884912 0.861883715366442 1.0 1.0 12 O95684,Q09161,P63167,P02786,O75592 5
Envelope proteins and their potential roles in edmd physiopathology 0.3911972281630645 0.1587734504044781 0.8738473669473774 1.0 1.0 17 Q14739,P42166 2
Amyotrophic lateral sclerosis als 0.3689063736334234 0.1549450743453466 0.8768646185311659 1.0 1.0 11 P63000,Q16539,P04637,P07196,P42574,Q9BUN8 6
Mecp2 and associated rett syndrome 0.4052296204483466 0.149120520905511 0.8814585335900387 1.0 1.0 22 P35637,Q96ST3,P62753,P67809,P21359,O75376,P42345,Q99640,P31943,P52597,Q03518 11
Ras and bradykinin pathways in covid19 0.3501111573833849 0.1411325359605592 0.8877652409093062 1.0 1.0 4 P61586 1
Mitochondrial immune response to sarscov2 0.3537658287568989 0.1316832740560458 0.895234815668676 1.0 1.0 9 Q9Y6M9 1
Translation factors 0.4463900467301177 0.1300307642200449 0.8965420869856866 1.0 1.0 36 O15372,P20042,O75822,P49770,Q13144,P55010,O75153,Q9H074 8
Ppar signaling pathway 0.3789249686512255 0.1241865651264633 0.9011675593670548 1.0 1.0 17 O00767,Q08426,Q15067,O15254 4
Aryl hydrocarbon receptor pathway wp2586 0.3457350873691672 0.1192196710663936 0.905101322537 1.0 1.0 8 Q16543,P21359,O00170 3
Phosphoinositides metabolism 0.3415547923821321 0.1173700335521644 0.9065668296758032 1.0 1.0 7 Q9NTJ5,Q01968,O00443,P48426,Q99570,O95248 6
Nsp1 from sarscov2 inhibits translation initiation in the host cell 0.3649669015198684 0.1146953040310656 0.9086866362051812 1.0 1.0 14 O15372,P20042,P55010,O75822 4
G1 to s cell cycle control 0.4056469352650254 0.103690978748662 0.9174145859783256 1.0 1.0 27 P33993,P06493,P33991,Q07864,Q9Y619,Q9UBD5,P24941,Q14566,Q99640,P04637,P33992,P11802,O43913,P15927,P14635 15
Selenium micronutrient network 0.3589524638565071 0.0990439627497109 0.9211033644571875 1.0 1.0 14 Q8WTV0 1
Notch signaling 0.3345863503196117 0.099030649203716 0.9211139351618732 1.0 1.0 7 Q13363 1
Tryptophan metabolism 0.3582592231489862 0.0972828694289615 0.9225017596837272 1.0 1.0 14 P35610,P51648,Q15392 3
Mirna regulation of prostate cancer signaling pathways 0.335823831491102 0.0933180528201622 0.925650890586464 1.0 1.0 8 P49841,P28482,P42345 3
Nrf2 pathway 0.3734659247145028 0.0835174902176931 0.9334400707938308 1.0 1.0 20 P30043,Q8N1S5,P09601 3
Wnt signaling 0.3540718857395611 0.0784410739634184 0.937477201867621 1.0 1.0 15 P63000,P67870,P48729,P61586,Q8TAA9,P49841,Q13363 7
Mitochondrial complex i assembly model oxphos system 0.3911105979156756 0.0763417386665845 0.9391472200587204 1.0 1.0 26 Q9Y6M9,O43676,Q9P0J0,P03886 4
Circadian rhythm genes 0.4468223982906987 0.0715090727089474 0.9429926040676508 1.0 1.0 43 P54802,Q9BWF3,O75376,Q9Y2W1,P43490,Q03164,P11802,P04818,P78527,Q15233 10
Sulfation biotransformation reaction 0.3454942313688851 0.0670147995848533 0.9465699213215784 1.0 1.0 3 P00390,P11413 2
Folate metabolism 0.3468479767302134 0.0616728191892567 0.9508233858974252 1.0 1.0 15 Q99707,Q8WTV0 2
Netrinunc5b signaling pathway 0.3385491170184989 0.0586031439804297 0.953268206454812 1.0 1.0 13 P63000,Q16539,P62136,Q8TCG1,P61586,P28482,P30154,P42574 8
Ferroptosis 0.3714402876185864 0.0549494376853167 0.9561787457680913 1.0 1.0 23 Q9NZ45,P37268,P09601,P45880 4
Sarscov2 replication organelle formation 0.4769326683291849 0.054916228095384 0.956205203237794 1.0 1.0 2 Q14457 1
Interactions between loxl4 and oxidative stress pathway 0.3242906142812654 0.0529586775030818 0.9577648320587404 1.0 1.0 3 Q16543,Q9BQ95 2
Pi3kaktmtor signaling pathway and therapeutic opportunities 0.258889582033693 0.0374570669013539 0.9701205717547404 1.0 1.0 4 P49815,P49841,P42345 3
Proteasome degradation 0.4269475637583592 0.0351089348938391 0.9719928767909723 1.0 1.0 42 O00231,P10321,P28074,P60900,P28072,P46934,P28070,P04439,P49721 9
Nonalcoholic fatty liver disease 0.4442816531859923 0.0292028171271642 0.9767028344507198 1.0 1.0 48 O00217,O95298,P49840,P14406,P20674,P42574,Q96J02,Q9UDW1,P31751,Q9P0J0,P14854,P22695,O43676,O75306,Q86Y39,O14949,P00403,Q9Y6M9,O75251 19
Small cell lung cancer 0.3244526735002262 0.0291432131109446 0.976750371342224 1.0 1.0 13 P42574,P11802,P31751 3
Tp53 network 0.3572319201995088 0.0209778117785392 0.9832633554167328 1.0 1.0 2 P04637 1
Microrna network associated with chronic lymphocytic leukemia 0.3167082294264419 0.0190490476412752 0.984801978136034 1.0 1.0 2 P04637 1
Glycogen synthesis and degradation 0.324840189475067 0.0043777832688883 0.9965070454762874 1.0 1.0 17 P49840,P52789,Q16537 3