msigdb_reactome/result.tsv

Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
Slc mediated transmembrane transport	0.652048078089647	2.8225435231422793	0.0047644354621674	0.9987459467444204	0.2848703708057432	20	Q8TB61,O00400,P53985,Q9UBX3,Q70HW3,Q99808	6
Circadian clock	0.7347791060179708	2.7298324422873605	0.0063366523417296	0.999862678131502	0.2848703708057432	13	P43490,Q9BWF3,P62136,O75376,Q86X55	5
Protein localization	0.4209946136381969	2.507791720884931	0.0121488253327117	0.9999999625512492	0.3219907154880079	73	Q99595,Q5JRX3,P51648,Q9NS69,Q9NR77,P09601,O43681,Q10713,Q9Y584,P40855,Q08426,P21796,P46379,O15254,Q15067	15
Biological oxidations	0.4628999773232393	2.297344565219781	0.0215991214147506	0.999999999999946	0.4120054580205153	43	Q96DG6,Q8TB61,Q9NUJ1,O00170,O43169,P21266,P10768,Q16850,P21964,P16435,Q15185,P07099	12
Sphingolipid de novo biosynthesis	0.7063744734770482	2.2931226528091933	0.0218409445564335	0.9999999999999616	0.4120054580205153	11	O95470,P51648,O15121,Q96G23,Q06136	5
Mitophagy	0.7027337069871971	2.273916662621281	0.0229709976594711	0.9999999999999925	0.4120054580205153	11	Q9NS69,Q8N4H5,P21796,P67870,O94826,Q13501	6
Mitochondrial protein import	0.4833878329297953	2.14085311947315	0.0322858847077254	1.0	0.4911143897591645	33	Q99595,Q9Y584,Q9NS69	3
Metabolism of porphyrins	0.6773448244094097	2.138872458233408	0.0324459991593586	1.0	0.4911143897591645	11	P22830,P09601,P30519,P33527	4
Initiation of nuclear envelope ne reformation	0.5677984718936562	2.1090861392997735	0.0349371470456605	1.0	0.5091361324674905	18	Q86Y07,P50402,Q8IXJ6,P42166,Q14739,O95067,Q86XL3	7
Selective autophagy	0.5051437723233397	2.1043117119932173	0.035351265080372	1.0	0.5098599984272211	27	Q9NS69,Q8N4H5,P21796,P67870,O94826,Q13501,Q8IWA4,P63167	8
Proton coupled monocarboxylate transport	0.9407730673316708	2.05686349414881	0.0396993583939766	1.0	0.549895073199736	2	P53985	1
Pink1 prkn mediated mitophagy	0.6980568292195982	1.9964298466088637	0.0458871547562647	1.0	0.5843575675112274	9	Q9NS69,Q8N4H5,P21796,O94826,Q13501	5
Pyruvate metabolism	0.6061432494595305	1.995910065516227	0.0459437128988571	1.0	0.5843575675112274	13	Q8NCN5,P53985,P21796	3
Sphingolipid metabolism	0.4866909556028573	1.9933560441514315	0.0462224734983045	1.0	0.5843575675112274	28	O95470,P51648,P27544,O43681,Q96G23,Q16739,P04062,O15121,Q13510,Q06136	10
Tnfr1 induced nfkappab signaling pathway	0.7250806222392197	1.8797516644627608	0.0601419307620822	1.0	0.6481780067393449	7	P63244	1
Vitamin d calciferol metabolism	0.896820448877806	1.861899516368115	0.062617255245216	1.0	0.6537423302029021	2	P38435	1
Cholesterol biosynthesis	0.5293200134268284	1.845795706662892	0.0649218742349238	1.0	0.6547544173519264	18	Q15392,Q14534,O75845,Q16850,Q15800,Q14739	6
Transport of inorganic cations anions and amino acids oligopeptides	0.6679839403230745	1.84473567898765	0.0650759980567037	1.0	0.6547544173519264	9	Q9UBX3	1
Srp dependent cotranslational protein targeting to membrane	0.3404247381739372	1.8398151632347663	0.0657953784888303	1.0	0.6547544173519264	93	P18077,P61927,Q15629,P67812,P27635,P46778,P62910,P61254,P62753,P25398,P09132,P46782,P39023,P46776,P62266,P62273,P62263,P43307,P15880,Q9Y3U8,P84098,P62917,P83881,P61513,Q9Y5M8	25
Respiratory electron transport	0.3793083278499508	1.829361652105762	0.0673454483802424	1.0	0.6547544173519264	53	Q9P0J0,P31930,Q9Y6M9,P14854,O43676,Q9UDW1,O14949,Q86Y39,P20674,P13073,P00403,P03886,O95298,O75306,P31040,P51970	16
Heme signaling	0.7074302361233578	1.796999491481556	0.0723357004897489	1.0	0.6597615598193363	7	P09601,Q86X55	2
Nr1h2 and nr1h3 mediated signaling	0.7055817103799977	1.7882987607938987	0.0737278196948549	1.0	0.6597615598193363	7	Q9HCE1,O00767	2
Activation of the pre replicative complex	0.4712364691401446	1.7631938751284706	0.0778677964504777	1.0	0.6831143980465095	25	Q9UBD5,Q14181,P27694,P56282,P49642,Q7L590,Q14566,Q9Y619,P15927,O00311	10
Heme degradation	0.8237606808224105	1.7616643696274032	0.0781260212204728	1.0	0.6831143980465095	5	P09601,P30519	2
Abc family proteins mediated transport	0.3720820202681322	1.745736047125614	0.0808568282777797	1.0	0.692869520175954	56	Q14997,P28072,P60900,P20042,P33527,P40855,O75832,P08183,Q9GZP9,P20618,O75027,P49721,Q92530	13
Biosynthesis of specialized proresolving mediators spms	0.8597256857855382	1.695800227962741	0.089923719313862	1.0	0.7141037272009417	2	Q14914	1
O linked glycosylation of mucins	0.8063785088456041	1.688999521379351	0.0912195216760984	1.0	0.7141037272009417	5	Q8N4A0	1
O linked glycosylation	0.7089199334227154	1.6827046774216416	0.0924322758103197	1.0	0.7141037272009417	6	Q8N4A0	1
Class i peroxisomal membrane protein import	0.6138558855323563	1.6780007914577566	0.0933469445068657	1.0	0.7141037272009417	10	Q9NR77,P51648	2
Tp53 regulates transcription of several additional cell death genes whose specific roles in p53 dependent apoptosis remain uncertain	0.8528678304239414	1.6649743654775095	0.095917870210048	1.0	0.7141037272009417	2	P53611	1
Phase i functionalization of compounds	0.5216373365545042	1.6604050592404591	0.0968329930493618	1.0	0.7141037272009417	16	O00170,O43169,Q16850,Q15185,P07099	5
Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways	0.5588676477029723	1.6354423152901196	0.1019563579092817	1.0	0.7143659173718138	12	P42575,P09601,O15111	3
Pi3k akt signaling in cancer	0.5795025201582322	1.6013580700424073	0.1092976340530069	1.0	0.7158867090845438	11	P49840,P63000,O15111,P49841	4
Metabolism of steroids	0.3845766825725134	1.5984635434079115	0.1099398526646742	1.0	0.7158867090845438	46	Q15392,Q14534,O75845,Q86X55,P04062,Q16850,P38435,Q15800,Q14739,P15121,P30536,O00767	12
Aryl hydrocarbon receptor signalling	0.9254943144261022	1.5925578028809613	0.111259426177503	1.0	0.7158867090845438	3	O00170	1
E2f mediated regulation of dna replication	0.5505227820984643	1.5860007828808018	0.1127391319665414	1.0	0.7158867090845438	12	P49643,P30154,P06493,Q9UBD5,O43913,Q14181,P49642,Q9Y619	8
Phase ii conjugation of compounds	0.4455299130889242	1.5845458598896138	0.1130695541829223	1.0	0.7158867090845438	26	Q99735,Q8TB61,Q9NUJ1,P21266,P10768,P21964	6
Bmal1 clock npas2 activates circadian gene expression	0.9183349082306914	1.5800948725565025	0.1140851413775982	1.0	0.7158867090845438	4	P43490	1
Activation of atr in response to replication stress	0.4482425228329204	1.5777469849399877	0.1146237475589262	1.0	0.7158867090845438	25	Q9UBD5,O14757,Q13535,P27694,Q7L590,Q14566,Q9Y619,P15927,O00311	9
Uptake and actions of bacterial toxins	0.6604143920421944	1.573874883119022	0.1155163776548786	1.0	0.71825516595189	7	P13639,Q7L0J3	2
P75ntr regulates axonogenesis	0.9189368736790378	1.566838538079799	0.1171524368774763	1.0	0.7226010207715656	3	Q9NQC3	1
Tp53 regulates transcription of dna repair genes	0.433920118296399	1.5516336389601897	0.1207499094308393	1.0	0.7226010207715656	28	O14757,Q13535,P18615,Q14241,Q14004,Q8IXH7,P04637	7
Autophagy	0.3898726149596608	1.551157557340426	0.1208639305650796	1.0	0.7226010207715656	43	Q14457,Q9NS69,Q8N4H5,O95352,P21796,P67870,Q9NT62,P63167	8
Cytochrome p450 arranged by substrate type	0.9134941326333692	1.5454784665845205	0.1222305735184887	1.0	0.7233525321000513	3	Q16850	1
The citric acid tca cycle and respiratory electron transport	0.3243619042947833	1.5383119857174563	0.1239723505444567	1.0	0.7233525321000513	91	Q9Y6M9,P53985,P21796,P03886,O95298,Q8NCN5,Q9P0J0,O43676,Q86Y39,P31040,P35613,P51970,P48735,O75964,Q9H9P8,Q9UDW1,O14949,P00403,O75306,P31930,P14854,O75947,P20674,P13073	24
Platelet homeostasis	0.5301700206766288	1.5367458656799071	0.1243555546324248	1.0	0.7233525321000513	13	P23634,Q16537,P30626,P63218,Q06124,Q16539,P16615,P62873	8
Gpvi mediated activation cascade	0.7686929012372059	1.530372021275849	0.1259246703503735	1.0	0.7233525321000513	5	P60953,P61586,P63000	3
Cytoprotection by hmox1	0.349471827126494	1.50572552943808	0.1321376474903099	1.0	0.7366004186220036	66	P14854,Q14997,Q86X55,P09601,P28072,P60900,O75376,P33527,O75832,P67870,P20674,P20618,P00403,P30519,P49721,Q92530,P13073	17
Diseases of immune system	0.9031282810850316	1.5047711335381873	0.1323829276338766	1.0	0.7366004186220036	3	P09429	1
Ras processing	0.667366675958565	1.492073651049438	0.1356798384851549	1.0	0.7366004186220036	6	O60725,P49354	2
Oncogene induced senescence	0.6668353025958813	1.4896224487084864	0.1363235360101562	1.0	0.7366004186220036	6	P11802,P04637,Q9HCE1	3
Transport of vitamins nucleosides and related molecules	0.6182000606407618	1.487379957072509	0.1369144874516377	1.0	0.7366004186220036	8	O00400,Q99808	2
Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins	0.349571210243717	1.4851552503096006	0.1375027030801008	1.0	0.7366004186220036	62	Q9P0J0,O75964,Q9Y6M9,P31930,P14854,O43676,Q9UDW1,O75947,O14949,Q86Y39,P20674,P13073,P00403,P03886,O95298,O75306,P31040,P51970	18
Maturation of sars cov 1 nucleoprotein	0.8126558603491292	1.4837851764828025	0.1378659209111461	1.0	0.7366004186220036	2	P49840	1
Akt phosphorylates targets in the cytosol	0.6654637259773623	1.4832940986120742	0.1379962895919475	1.0	0.7366004186220036	6	P49840,O15111	2
Constitutive signaling by akt1 e17k in cancer	0.6390535058684977	1.471414366729488	0.1411790904486718	1.0	0.7414743480951164	7	P49840,O15111	2
Recycling of eif2 gdp	0.6370279975188269	1.4616706719457726	0.1438314777580425	1.0	0.7414743480951164	7	Q13144,P49770,P20042	3
Sulfur amino acid metabolism	0.5534778666589283	1.4545669269549673	0.1457891926212859	1.0	0.7416693835533785	11	Q13126	1
Tnf signaling	0.5904674438797881	1.4449174519205104	0.1484810736788846	1.0	0.7497803058469595	9	P63244,P78536	2
Nod1 2 signaling pathway	0.6053333998055785	1.4227657111256091	0.1548040844300224	1.0	0.765268247765376	8	P42575,O15111	2
Dscam interactions	0.7976932668329201	1.4162987600436598	0.1566880507336008	1.0	0.7661668302805833	2	Q16539	1
Mapk1 erk2 activation	0.7951995012468851	1.405054486632179	0.1600050766192837	1.0	0.7745574470255294	2	P28482	1
Dna damage recognition in gg ner	0.4888184831904156	1.390302173998873	0.164437137984116	1.0	0.7810833107051108	15	Q9H981,P25490	2
Traf6 mediated nf kb activation	0.6443555192069658	1.3856894165900215	0.1658417612371385	1.0	0.7838264323336379	6	P09429	1
Beta oxidation of very long chain fatty acids	0.6204659596733999	1.3818509923340536	0.1670174582238979	1.0	0.7867253335193036	7	Q15067	1
Response of eif2ak4 gcn2 to amino acid deficiency	0.3290048112974606	1.3691352472857947	0.1709570022550375	1.0	0.7939270606531256	79	P18077,P20042,P61927,P27635,P46778,P62910,P61254,P62753,P25398,P46782,P39023,P46776,P62266,P62273,P62263,P15880,Q9Y3U8,P84098,P08243,P62917,P83881,P61513	22
Rho gtpases activate wasps and waves	0.4695402577094119	1.3677708148041474	0.1713838258164717	1.0	0.7939270606531256	17	P60953,Q92747,P28482,P63000,O15143,Q9UQB8	6
Eukaryotic translation initiation	0.3076574120613252	1.3653866580969884	0.1721315550238884	1.0	0.794538567905414	102	P18077,O75822,P20042,P61927,P27635,P46778,P62910,Q13347,P61254,P62753,P25398,P46782,P39023,P46776,P62266,P49770,P62273,P62263,P15880,Q13144,Q9Y3U8,P84098,P62917,P83881,P11940,P61513	26
Cyclin a b1 b2 associated events during g2 m transition	0.5535073045827889	1.351126536486432	0.1766549022507559	1.0	0.794538567905414	10	P30154,P06493,Q99640,P24941,O95067,Q9Y570,P53350	7
Interconversion of nucleotide di and triphosphates	0.4585197541056632	1.348088555582239	0.1776299018856919	1.0	0.794538567905414	18	Q9H773,Q9NRF8,P35754,P17812,P23921,P00390,P04818,Q16881	8
Synthesis of leukotrienes lt and eoxins ex	0.8599937636420346	1.33524870217509	0.1817949618371912	1.0	0.794538567905414	3	Q14914,P33527	2
Abacavir transport and metabolism	0.7793017456359136	1.333427441192035	0.1823915721145279	1.0	0.794538567905414	2	P08183	1
Condensation of prometaphase chromosomes	0.5501928472299235	1.3330309063011432	0.1825216616141221	1.0	0.794538567905414	10	O95067,P67870,Q15003	3
E2f enabled inhibition of pre replication complex formation	0.6315980053077657	1.3265478554234411	0.1846582947908057	1.0	0.794538567905414	6	Q9Y619,Q9UBD5,P06493	3
Peroxisomal lipid metabolism	0.4827612823383815	1.305893806855049	0.1915886729782934	1.0	0.794538567905414	14	Q08426,Q15067,P51648	3
Methylation	0.6159897781152186	1.2541081875525282	0.2098026848108607	1.0	0.8117603168935206	6	P78417,P21964,P23526	3
Ptk6 regulates rho gtpases ras gtpase and map kinases	0.7008906943106913	1.242753272730528	0.2139587662904261	1.0	0.814838938637744	5	P61586,P46108	2
Raf independent mapk1 3 activation	0.6133037797174321	1.2416386852925094	0.2143699017950084	1.0	0.814838938637744	6	P28482,P06493	2
Polb dependent long patch base excision repair	0.6993415480619067	1.236175179839712	0.2163934544908237	1.0	0.8159958027834565	5	P27695,P18858,P39748	3
Transcriptional regulation by e2f6	0.5263074055111752	1.2024514930598615	0.2291886489179613	1.0	0.8460024270085169	10	O14757,O00311	2
Cyclin d associated events in g1	0.542103003270944	1.1913731558211098	0.2335071263967694	1.0	0.8467873671364665	9	P63208,P30154,Q13309,P11802,Q00534	5
Ion transport by p type atpases	0.5070360963663478	1.1905284704526906	0.2338387468006886	1.0	0.8467873671364665	11	P23634,Q9HD20	2
Synthesis of pips at the golgi membrane	0.558452742590365	1.1862821222815485	0.2355109043572669	1.0	0.8467873671364665	8	Q9UBF8,Q9NTJ5,Q10713,Q9BTU6,Q01968	5
Cd163 mediating an anti inflammatory response	0.8201340576250221	1.1790829839186865	0.2383651336160102	1.0	0.8477118472394338	3	P78536	1
Basigin interactions	0.5990705108738952	1.1755781058566577	0.2397635087852041	1.0	0.8477118472394338	6	P53985	1
Acyl chain remodelling of pc	0.7422069825436441	1.1670856279793245	0.2431757912440302	1.0	0.8497229714842567	2	Q8NF37	1
G protein beta gamma signalling	0.682172167241552	1.163335609188028	0.2446933634349775	1.0	0.8515572523520735	5	P60953,P61586,P63218	3
Nonsense mediated decay nmd	0.3044315168134788	1.152121654686589	0.2492710858190192	1.0	0.8586227271761058	87	P18077,P61927,P27635,P46778,P62910,P61254,P62753,P25398,Q09161,P46782,P39023,P46776,P62266,P62273,P62263,P15880,Q9Y3U8,P84098,P62917,P83881,P11940,P61513	22
Tp53 regulates transcription of cell death genes	0.593150963793417	1.148124460996507	0.2509171875010398	1.0	0.8586227271761058	6	P42575,P53611	2
Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux	0.6783166681169128	1.1470025840522324	0.2513805529501094	1.0	0.8586227271761058	5	Q9HCE1	1
Mitotic g1 phase and g1 s transition	0.3108978550398352	1.1315772620436644	0.2578122040273078	1.0	0.8586227271761058	80	P06493,P11802,O75832,Q7L590,Q9UBD5,P60900,P27694,P49642,Q14566,P49721,Q9Y619,P15927,P04818,P62191,O00311,P28066,O43913,P28072,Q13309,P20618,Q92530,P00374,Q14181,P56282	24
Hedgehog ligand biogenesis	0.3514140597120966	1.1257819781243914	0.2602578142159579	1.0	0.8586227271761058	42	Q14997,P07237,P28072,P60900,O75832,Q9GZP9,P78536,P20618,P49721,Q92530	10
Gpcr ligand binding	0.5083322782625519	1.104200711862661	0.2695060809392342	1.0	0.869140448349332	10	P04083,P63218,Q9NZJ7,Q9NRV9,Q9Y3E5,P07602,P62873	7
Deubiquitination	0.288850007886944	1.0972493172318256	0.2725324198246459	1.0	0.8696526710393461	100	P06493,Q9UPU5,O75832,P21796,Q9H981,P25490,Q14457,O94966,P60900,P51784,Q96RL1,P45880,P49721,P62191,Q9Y4E8,P61586,P28072,Q9NWV8,O94826,P20618,P04637,Q92530,Q14997,Q9Y277	24
Hiv transcription elongation	0.4145194869166592	1.0901178569030965	0.2756612312521951	1.0	0.8696526710393461	19	Q14241,P18615,Q09161,Q8IXH7	4
Sialic acid metabolism	0.787736365196564	1.0846102045541115	0.2780943334592898	1.0	0.8723183240124359	4	Q8NFW8,Q9NR45	2
Gamma carboxylation hypusine formation and arylsulfatase activation	0.4658648434447409	1.0790345676768816	0.2805723180861501	1.0	0.8729489295658882	12	O60725,O43681	2
Synthesis of pc	0.576716394865534	1.0720368363122244	0.283703487188254	1.0	0.8729489295658882	6	Q9NQZ5,Q8NF37	2
Dna replication initiation	0.5353253671211696	1.0696491452867871	0.2847772650344335	1.0	0.8729489295658882	8	P56282,P49642,Q14181	3
Mrna decay by 3 to 5 exoribonuclease	0.4457066185042647	1.0694114549599911	0.2848843079457901	1.0	0.8729489295658882	14	Q6PGP7	1
Regulation of tnfr1 signaling	0.5760037928144875	1.068743674593654	0.2851851858524723	1.0	0.8729489295658882	6	P63244	1
Insertion of tail anchored proteins into the endoplasmic reticulum membrane	0.4852347849790831	1.0665215894400617	0.2861879245670014	1.0	0.8729489295658882	11	O43681,P09601,P51648,P46379	4
Rho gtpases activate nadph oxidases	0.5711312033436036	1.046242838255761	0.2954489292610001	1.0	0.8863638705076758	6	P28482,P63000,Q16539	3
Transport of bile salts and organic acids metal ions and amine compounds	0.7765196387882795	1.0424820952462222	0.2971882223615392	1.0	0.8863638705076758	4	P53985	1
Pcna dependent long patch base excision repair	0.4074896770372094	1.0388313317579465	0.2988831868948978	1.0	0.8863638705076758	19	P18858,P39748,P27694,P56282,P27695,P15927	6
Sema4d induced cell migration and growth cone collapse	0.5680695665953052	1.0321211682687883	0.3020153584962919	1.0	0.8863638705076758	6	P61586	1
Potassium channels	0.7113466334164626	1.0303488635689282	0.3028462688367899	1.0	0.8863638705076758	2	P63218	1
Prostacyclin signalling through prostacyclin receptor	0.7113466334164626	1.0303488635689282	0.3028462688367899	1.0	0.8863638705076758	2	P63218	1
G protein activation	0.7113466334164626	1.0303488635689282	0.3028462688367899	1.0	0.8863638705076758	2	P63218	1
Presynaptic function of kainate receptors	0.7113466334164626	1.0303488635689282	0.3028462688367899	1.0	0.8863638705076758	2	P63218	1
Glucagon type ligand receptors	0.7113466334164626	1.0303488635689282	0.3028462688367899	1.0	0.8863638705076758	2	P63218	1
Inwardly rectifying k channels	0.7113466334164626	1.0303488635689282	0.3028462688367899	1.0	0.8863638705076758	2	P63218	1
Dap12 interactions	0.6487011512996774	1.0220426437459935	0.3067607177159959	1.0	0.8909679454688305	5	P10321,P63000	2
Neddylation	0.3103805470196399	1.005661789465029	0.3145782898033209	1.0	0.8963282150069063	66	Q9NV06,Q8NEZ5,Q14997,P28072,P61962,P60900,Q9Y5A7,O75832,Q15345,P20618,Q9BT78,P49721,Q92530,P62191,Q13098	15
Fructose metabolism	0.7753719683354734	1.0056491496730728	0.3145843721288734	1.0	0.8963282150069063	3	P15121	1
Processive synthesis on the lagging strand	0.4355896202090459	1.0051665261872076	0.3148166705874955	1.0	0.8963282150069063	14	P18858,Q14181,P51530,P27694,P39748,P15927	6
Metabolism of steroid hormones	0.5620347373083191	1.004328083263216	0.3152205016321643	1.0	0.8963282150069063	6	P15121,P30536	2
Fgfr2 alternative splicing	0.4437648455240998	1.0026765722409634	0.3160169370997958	1.0	0.8967701724190961	13	Q09161,P31943,P52597	3
Pregnenolone biosynthesis	0.7636503548628035	0.994372617026442	0.3200414942861336	1.0	0.9026976824723808	4	P15121,P30536	2
Cd28 dependent vav1 pathway	0.7608365856813312	0.9838905197592271	0.325169345467299	1.0	0.9080078129915196	4	P60953	1
Metalloprotease dubs	0.5369195600628818	0.9786144987143204	0.3277704926828946	1.0	0.9096035282474884	7	Q9NWV8	1
Complex i biogenesis	0.3654182217330002	0.9690905279651346	0.3325000232454607	1.0	0.9120932010203912	28	Q9P0J0,Q9Y6M9,O43676,P51970,Q86Y39,P03886,O95298,O75306,O95299	9
Synthesis of very long chain fatty acyl coas	0.51234821386111	0.9544256977528324	0.3398682035198144	1.0	0.921464373496551	8	Q4G176,O60488,Q9P035,P33121	4
Epha mediated growth cone collapse	0.495781520100764	0.9491427898059028	0.3425479939886697	1.0	0.9262910460260484	9	P61586	1
Activation of nima kinases nek9 nek6 nek7	0.630889235569427	0.9475243797695974	0.3433716391679984	1.0	0.9262910460260484	5	O95067,P14635,P06493,P53350	4
Cooperation of pdcl phlp1 and tric cct in g protein beta folding	0.4339837227715549	0.9426719347488836	0.3458487328859556	1.0	0.927537866281896	13	P67870,Q13371,P63218,P49368	4
Glycogen breakdown glycogenolysis	0.5292158152678073	0.9417937747142476	0.3462982330039006	1.0	0.927537866281896	7	P35573,P46976,P46020	3
Slc transporter disorders	0.3529903224848917	0.9404171105087192	0.3470036488776973	1.0	0.927537866281896	32	P53985,O00400,Q9BTX1	3
Endosomal vacuolar pathway	0.7489082969432398	0.9396203687286466	0.3474123244687015	1.0	0.927537866281896	4	P10321,Q9UIQ6,P04439	3
The phototransduction cascade	0.5469143936505378	0.9349935684254184	0.3497916139654233	1.0	0.9317171576948408	6	P53582,P49354	2
Platelet sensitization by ldl	0.5438682450594774	0.9210876682839928	0.3570046579789934	1.0	0.933123396043972	6	Q06124,Q16539,Q16537	3
Parasite infection	0.3650712465423389	0.9205884324954764	0.3572653437643325	1.0	0.933123396043972	26	P60953,Q92747,P28482,P63000,P46108,O15143,Q9UQB8	7
Suppression of apoptosis	0.5434472962246408	0.919167862935961	0.3580077777061916	1.0	0.933123396043972	6	P28482,P49840,Q63HN8	3
Cytosolic trna aminoacylation	0.3713133026305551	0.9166298881867492	0.3593366170034451	1.0	0.933123396043972	23	P49591,Q9Y285,P26639,P49589,P26640,Q9P2J5,P54136,P07814,O43776	9
Caspase activation via dependence receptors in the absence of ligand	0.6851620947630965	0.9163092872342954	0.3595046982722105	1.0	0.933123396043972	2	P42574	1
Regulation of tp53 expression and degradation	0.4736824215272505	0.9159988446622748	0.3596675008750611	1.0	0.933123396043972	10	O96017,P30154,P06493,P24941,P04637	5
Eukaryotic translation elongation	0.2959314129125048	0.9147733510353886	0.3603106275980552	1.0	0.933123396043972	79	P18077,P61927,P27635,P46778,P62910,P61254,P62753,P25398,P46782,P39023,P46776,P62266,P62273,P62263,P15880,Q9Y3U8,P84098,P62917,P83881,P61513	20
Resolution of ap sites via the multiple nucleotide patch replacement pathway	0.3808164082521162	0.9116786750511856	0.3619378929638646	1.0	0.933123396043972	21	P18858,P39748,P27694,P56282,P27695,P15927	6
Activation of bh3 only proteins	0.4575290782483162	0.91006259302318	0.3627895006602544	1.0	0.933123396043972	11	Q04917,P63167	2
Cellular response to chemical stress	0.2978591331030958	0.9100167334392144	0.3628136850351355	1.0	0.933123396043972	76	P14854,Q14997,Q86X55,P09601,P07237,P28072,P60900,O75376,P33527,O75832,P67870,P20674,P20618,P00403,P30519,P49721,Q92530,P13073	18
Creatine metabolism	0.7496102276270737	0.9075191406048868	0.3641323323136851	1.0	0.933123396043972	3	P12532,P12277	2
Regulation of expression of slits and robos	0.3004534384661642	0.9064606620759552	0.3646920771914193	1.0	0.933123396043972	126	P18077,O75832,P61927,P27635,P46778,P62910,P61254,P62753,P60900,P25398,P35268,Q09161,P46782,P49721,P39023,P46776,P62266,P28072,P62273,P62263,P20618,Q92530,O43347,P15880,Q9Y3U8,Q14997,P84098,P62917,P83881,P11940,P61513	31
Ub specific processing proteases	0.2967721525250814	0.9051384618212392	0.3653920382469993	1.0	0.933123396043972	77	Q14457,O94966,Q14997,P28072,P60900,Q9Y277,O75832,P21796,P51784,P45880,P20618,P04637,P49721,Q92530,P62191,Q9Y4E8	16
Tak1 activates nfkb by phosphorylation and activation of ikks complex	0.5213660492608745	0.9044253670254532	0.3657698922373829	1.0	0.933123396043972	7	P09429	1
Abortive elongation of hiv 1 transcript in the absence of tat	0.434813742970217	0.8941778902935041	0.3712267198831713	1.0	0.936282336413966	12	P18615,Q09161,Q8IXH7	3
Transcription of the hiv genome	0.3732709712226228	0.8917754663475563	0.3725132942154689	1.0	0.936282336413966	22	Q14241,P18615,Q09161,Q8IXH7	4
Signaling by braf and raf1 fusions	0.3654419713153299	0.8864499242383646	0.3753751268997281	1.0	0.936282336413966	24	P30086,O95352,Q9NRY5,Q96PU8	4
Nucleotide biosynthesis	0.4157512504965599	0.8801996085689717	0.3787511855111205	1.0	0.936282336413966	14	Q06203,P30520	2
Formation of fibrin clot clotting cascade	0.7421655343760494	0.8794791942821626	0.3791415092135928	1.0	0.936282336413966	3	P42785	1
Cobalamin cbl vitamin b12 transport and metabolism	0.6086043350437562	0.8553204889810583	0.3923737477580036	1.0	0.954662388023386	5	Q96EY8	1
Mitochondrial calcium ion transport	0.3946349884286599	0.8531240604560626	0.3935905099492593	1.0	0.9559602837135658	17	P21796,P45880	2
Hsf1 activation	0.4099235385618406	0.8438463699713626	0.3987552599988908	1.0	0.9651533023156544	14	Q15185,P15927,P27694	3
Formation of the early elongation complex	0.4042914053570223	0.8409145247796709	0.4003958207706009	1.0	0.9674503510502084	15	P18615,Q09161,Q8IXH7	3
Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand	0.3449948570237581	0.8359274877049336	0.4031956975489736	1.0	0.9691937815653164	30	Q9UJW0,P31689,P31948,O60884,Q15185,P63167	6
Rho gtpases activate ktn1	0.5055533381120619	0.8297207897574744	0.406696664337159	1.0	0.975932475827934	7	P60953,P61586,Q07866	3
Response of eif2ak1 hri to heme deficiency	0.7180880279999969	0.8267529673204624	0.4083770929143193	1.0	0.9776577895790356	4	P08243,P20042	2
Synthesis of pa	0.4424545264711405	0.8259837672300323	0.4088133001456295	1.0	0.9776577895790356	11	Q8N2A8	1
Tp53 regulates transcription of genes involved in g1 cell cycle arrest	0.6636533665835458	0.824565176272439	0.4096184987965641	1.0	0.9779117403010122	2	P04637	1
Regulation of tp53 activity through phosphorylation	0.3392243029502358	0.8193855885780229	0.4125664545864	1.0	0.9785934052663908	32	Q9Y5B9,O96017,Q13526,O14757,Q13535,P51530,P27694,Q16539,P67870,P40938,P04637,P15927	12
Heme biosynthesis	0.521199798963468	0.8184598215225755	0.4130946752290256	1.0	0.9785934052663908	6	P22830	1
Transport of small molecules	0.3174049335395856	0.8172732187669294	0.4137723079838711	1.0	0.9785934052663908	153	P20042,P33527,P53985,P21796,P16615,P30519,Q99808,Q9HD20,Q8TB61,Q8N4V1,P09601,O00400,Q10713,Q9UBX3,P45880,Q8WTV0,Q70HW3,P49721,P35613,Q93050,P07237,P28072,P35610,P20618,P12235,O75027,Q92530,P23634,Q14997,P40855,Q9Y277,P08183,Q9GZP9,O15118	34
G2 m dna replication checkpoint	0.7149218589855295	0.8153062997579997	0.4148970036405575	1.0	0.9785934052663908	4	Q99640,O95067	2
G2 m checkpoints	0.2723336722430331	0.7973946569585866	0.4252218613897338	1.0	0.9896286998486586	93	P06493,O14757,O75832,Q7L590,O95067,Q9UBD5,Q99640,P60900,P27694,Q96RL1,Q14566,P49721,Q9Y619,P15927,P62191,O00311,O96017,P28066,P28072,Q9NWV8,P20618,P04637,Q92530,Q04917,Q14997,Q13535,P51530	27
Orc1 removal from chromatin	0.2961170454309284	0.796945938297577	0.4254824295565398	1.0	0.9896286998486586	51	P20618,Q9UBD5,Q14997,P28072,P60900,P49721,O75832,Q14566,Q9Y619,Q92530	10
Regulation of tp53 activity through methylation	0.709632527952761	0.79625467275416	0.4258840255754423	1.0	0.9896286998486586	4	O96017,P04637	2
Pyruvate metabolism and citric acid tca cycle	0.3385345253222162	0.7962250659605333	0.4259012308075862	1.0	0.9896286998486586	31	Q8NCN5,P53985,P21796,P35613	4
Aflatoxin activation and detoxification	0.7194760866589558	0.7951059076000616	0.4265518985051759	1.0	0.9896286998486586	3	Q99735	1
Ire1alpha activates chaperones	0.3491907297987467	0.7924430382612694	0.4281023928641172	1.0	0.9902645465001948	26	P49840,Q9Y5M8,Q06210,O94979,Q9HCU5,P43307,Q9NWM8	7
Cellular response to starvation	0.2732853450857024	0.7920312846574801	0.428342434863658	1.0	0.9902645465001948	92	P18077,P20042,P61927,P27635,P46778,P62910,P61254,P62753,P25398,P46782,P39023,P46776,P62266,P62273,P62263,P15880,Q9Y3U8,P84098,P08243,P62917,P83881,P61513	22
Cd28 co stimulation	0.4790197381265375	0.7897782006542096	0.4296573121698486	1.0	0.9902645465001948	8	P60953	1
Signaling by fgfr2	0.3680874220143116	0.7848657757539733	0.4325322699764635	1.0	0.9910246758077116	20	P52597,P28482,Q01085,P31943,Q09161,Q06124	6
Signaling by fgfr	0.3680874220143116	0.7848657757539733	0.4325322699764635	1.0	0.9910246758077116	20	P52597,P28482,Q01085,P31943,Q09161,Q06124	6
Cdt1 association with the cdc6 orc origin complex	0.3192928482437391	0.7846567620277234	0.4326548401177099	1.0	0.9910246758077116	41	Q9UBD5,Q14997,Q9Y619,P28072,P60900,O75832,P20618,P49721,Q92530	9
Signaling by type 1 insulin like growth factor 1 receptor igf1r	0.5906424242537208	0.7821163603000486	0.4341461927579657	1.0	0.9910246758077116	5	O14654	1
Maturation of sars cov 2 nucleoprotein	0.5130388782007113	0.7819611553150346	0.4342374026233933	1.0	0.9910246758077116	6	P49840,P49841,Q99873,P78362	4
Death receptor signalling	0.33953351346933	0.7766240940816186	0.4373805820833563	1.0	0.994951925747342	29	P42575,P61586,P63244,Q9NQC3,P78536	5
Pexophagy	0.6511845386533716	0.7723889250847394	0.4398841112767029	1.0	0.9990225189547196	2	Q13501	1
G beta gamma signalling through cdc42	0.7115684440286911	0.7661388356307383	0.443593697351905	1.0	0.999335881796026	3	P60953,P63218	2
Class b 2 secretin family receptors	0.7115684440286891	0.7661388356307308	0.4435936973519094	1.0	0.999335881796026	3	P63218,Q9Y3E5	2
Adp signalling through p2y purinoceptor 1	0.7115684440286856	0.7661388356307177	0.4435936973519172	1.0	0.999335881796026	3	Q16539,P63218	2
Purine ribonucleoside monophosphate biosynthesis	0.4445644308224102	0.7607476774447098	0.4468077915573338	1.0	1.0	10	P30520	1
Signal transduction by l1	0.4905095919508647	0.7595455909311617	0.4475262524366878	1.0	1.0	7	P28482,P67870	2
Ephb mediated forward signaling	0.3910291762336895	0.7571682844390278	0.4489490485731422	1.0	1.0	15	P60953,P61586,P63000,Q92747	4
Rho gtpases activate cit	0.4297944285847356	0.7562421928483997	0.4495039998734522	1.0	1.0	11	P60660,Q15334,P61586	3
Interferon alpha beta signaling	0.4414831124126699	0.7445662167803964	0.4565339972571292	1.0	1.0	10	P10321,Q06124,Q9Y3Z3,P04439	4
Interleukin 12 signaling	0.3406298442898009	0.7428429498556794	0.4575767688928183	1.0	1.0	27	P52597,Q99439,Q13126,O00170,P07237,O14979,P22626,Q9H3K6	8
Hiv elongation arrest and recovery	0.3885043248451408	0.7413866627961488	0.4584590288780137	1.0	1.0	15	Q14241,P18615,Q8IXH7	3
Transcriptional regulation of white adipocyte differentiation	0.3875096480869927	0.7351853179249279	0.4622266394494629	1.0	1.0	15	P11802,Q86X55	2
Displacement of dna glycosylase by apex1	0.6923964168323551	0.7348450234220847	0.4624338833622226	1.0	1.0	4	P27695	1
Resolution of abasic sites ap sites	0.3388441851204647	0.7285570931871473	0.4662726327093254	1.0	1.0	27	P29372,P18858,P39748,P27694,P56282,P27695,P15927	7
Glutathione conjugation	0.3911419501843983	0.7282533880271278	0.4664584899602111	1.0	1.0	14	P21266,Q99735,P10768	3
Signaling by erbb4	0.4509577540578001	0.7202168428596143	0.4713914952859965	1.0	1.0	9	O75376,P78536	2
Chk1 chk2 cds1 mediated inactivation of cyclin b cdk1 complex	0.4228325177334113	0.7183147664696607	0.4725632273515332	1.0	1.0	11	P06493,Q04917,O14757	3
Reduction of cytosolic ca levels	0.6870906281028575	0.7161686225141177	0.4738872352893633	1.0	1.0	4	P16615,P23634	2
Synthesis of ip3 and ip4 in the cytosol	0.6352867830423992	0.707147481015085	0.4794748319574085	1.0	1.0	2	Q01968	1
Downregulation of tgf beta receptor signaling	0.47903870715843	0.7067744826625857	0.4797066344611798	1.0	1.0	7	P62136,Q9Y3F4,Q9Y4E8	3
Diseases of mismatch repair mmr	0.6949822192436154	0.7062389478904274	0.4800395532536508	1.0	1.0	3	P20585	1
G1 s specific transcription	0.4197443383532647	0.7016011322668745	0.4829279453186836	1.0	1.0	11	Q9Y619	1
Mapk6 mapk4 signaling	0.2960970297526035	0.7010336570766869	0.4832820110675579	1.0	1.0	48	P60953,P06493,P28066,Q14997,P63000,Q9HCE1,P28072,P60900,O75832,Q16181,P20618,P49721,Q92530,P62191	14
Association of tric cct with target proteins during biosynthesis	0.3711441129194515	0.69715146820496	0.4857080072998947	1.0	1.0	17	P51784,P04062,P61962	3
Regulation of runx1 expression and activity	0.6919239164328056	0.695332309618595	0.4868470706151444	1.0	1.0	3	Q06124,Q9HCE1	2
Pyrimidine catabolism	0.6306109725685838	0.6882645059263125	0.4912862290798174	1.0	1.0	2	Q9H0P0	1
Gene and protein expression by jak stat signaling after interleukin 12 stimulation	0.3364114530283949	0.6757024084808213	0.4992296065069546	1.0	1.0	25	P52597,Q99439,Q13126,O00170,O14979,P22626,Q9H3K6	7
Signaling by erbb2	0.4145763230064649	0.6737964763424451	0.5004407153755515	1.0	1.0	11	P61586,Q9UNE7,Q16543	3
Peptide ligand binding receptors	0.4713204101552447	0.6716915908000298	0.5017800559315648	1.0	1.0	7	P04083,P07602	2
Class a 1 rhodopsin like receptors	0.4713204101552447	0.6716915908000298	0.5017800559315648	1.0	1.0	7	P04083,P07602	2
G beta gamma signalling through pi3kgamma	0.6736107416957023	0.6692584273524657	0.5033306410937066	1.0	1.0	4	P61586,P63218	2
Signaling by ptk6	0.3796390466125668	0.6589696634660606	0.5099152494892283	1.0	1.0	14	P61586,P63000,P11802,P46108,P04150	5
Signaling by robo receptors	0.2946900492295966	0.6584682346308717	0.5102373021284183	1.0	1.0	139	O75122,P18077,O75832,P61927,P27635,P46778,P62910,P61254,P62753,P60900,P25398,P35268,Q09161,P46782,P49721,P39023,P62191,P61586,P46776,P62266,P28072,P62273,P62263,P20618,Q92530,O43347,P15880,Q9Y3U8,Q14997,P84098,P62917,P83881,P11940,P61513	34
Cdc6 association with the orc origin complex	0.6704269025859982	0.658299307179332	0.5103458230948932	1.0	1.0	4	Q9UBD5,Q9Y619	2
Smooth muscle contraction	0.4115637739539636	0.6576901244306614	0.5107372694250014	1.0	1.0	11	P09493,P60660,P06753	3
Perk regulates gene expression	0.3793068019513861	0.6569890529294387	0.511187955417161	1.0	1.0	14	P41091,P20042,Q9NQT5,Q9NPD3,P08243,Q9Y2L1,Q92945	7
Costimulation by the cd28 family	0.3771673089938759	0.6442648407395216	0.5194037107689091	1.0	1.0	14	P60953,P63000,Q16537,Q06124	4
Lagging strand synthesis	0.3515000342982727	0.6411922289296368	0.5213977979335787	1.0	1.0	19	P18858,Q14181,P51530,P27694,P39748,P40938,P15927	7
Transcription of e2f targets under negative control by p107 rbl1 and p130 rbl2 in complex with hdac1	0.6742764123036961	0.6333352681057521	0.5265147268865336	1.0	1.0	3	P06493	1
Selenoamino acid metabolism	0.2607904945427089	0.6324329643103337	0.5271039993953135	1.0	1.0	93	P18077,P49207,P61927,P00390,P27635,P46778,P62910,P61254,P61313,P62753,P25398,P35268,P54136,P07814,P46782,P39023,P49591,P46776,P62266,P62273,P62263,P83881,P15880,Q9Y3U8,P84098,P62917,P42677,P61513,Q16881	29
Inhibition of replication initiation of damaged dna by rb1 e2f1	0.4773483432798471	0.6262498686030478	0.5311510624470936	1.0	1.0	6	P49642,P30154,Q14181	3
Interleukin 1 signaling	0.2861193591998838	0.624441264361669	0.5323378325716841	1.0	1.0	49	O15111,Q14997,P28072,P09429,P60900,O75832,P20618,Q13501,P49721,Q92530	10
G1 s dna damage checkpoints	0.3019503849727497	0.619691502165498	0.5354609114379014	1.0	1.0	41	O96017,O14757,Q14997,P28072,P60900,O75832,P20618,P04637,P49721,Q92530,P62191	11
Fcgamma receptor fcgr dependent phagocytosis	0.3116095298611394	0.6179799954664318	0.5365885253558518	1.0	1.0	34	P60953,Q92747,P28482,P63000,Q8IV08,P46108,O15143,Q9UQB8	8
Protein folding	0.3136548099432124	0.6177429879363642	0.53674477017764	1.0	1.0	33	P61962,P51784,P67870,P61758,Q99471	5
Regulation of hmox1 expression and activity	0.2959012869491641	0.6090400336463657	0.5424979035901663	1.0	1.0	44	Q14997,P09601,P28072,P60900,O75832,P67870,P20618,P49721,Q92530	9
Depolymerisation of the nuclear lamina	0.4275407704761054	0.6051376055600342	0.5450875692406065	1.0	1.0	9	P42166,P06493,P50402	3
Repression of wnt target genes	0.6546396208703996	0.6047064258477047	0.545374077764941	1.0	1.0	4	Q13363	1
Ra biosynthesis pathway	0.6656519988493902	0.6036687961113084	0.5460638638829611	1.0	1.0	3	Q8TC12	1
Platelet calcium homeostasis	0.5444163469082623	0.6003687143372007	0.5482605333077046	1.0	1.0	5	P16615,P23634	2
Fceri mediated mapk activation	0.4551109878479866	0.5993200734372015	0.5489594644254274	1.0	1.0	7	P28482	1
Alpha oxidation of phytanate	0.6623179413765709	0.5923205534721026	0.5536359551243428	1.0	1.0	3	P51648	1
Disorders of transmembrane transporters	0.2719852635355667	0.5883103427846961	0.556324004595856	1.0	1.0	77	P20618,Q14997,O00400,P28072,P60900,P53985,O75832,P78406,Q9GZP9,Q9BTX1,P49721,Q92530,P35613	13
Rac3 gtpase cycle	0.3096665847694232	0.584484699249487	0.558894256518637	1.0	1.0	33	O15498,P50402,P42166,O15173,Q9UQB8	5
Interferon gamma signaling	0.3802967971228523	0.5822431301979852	0.5604029256176875	1.0	1.0	12	P10321,Q06124,P29372,P04439	4
Sema4d in semaphorin signaling	0.4341743215638823	0.577158912366489	0.5638321101735555	1.0	1.0	8	P61586	1
Ovarian tumor domain proteases	0.4210792197056709	0.5741733786276817	0.5658504820432906	1.0	1.0	9	P61586,P04637	2
Tp53 regulates transcription of caspase activators and caspases	0.6512900453159929	0.5552917881170132	0.5786950948306337	1.0	1.0	3	P42575	1
Unfolded protein response upr	0.2931826512777558	0.5522091634191914	0.5808050569339802	1.0	1.0	42	P49840,Q9Y5M8,P20042,Q06210,O94979,Q9HCU5,P08243,P43307,Q92945,Q9NWM8	10
Activation of the ap 1 family of transcription factors	0.6493127478268368	0.5487383396153055	0.5831850310100095	1.0	1.0	3	Q16539	1
Abc transporters in lipid homeostasis	0.6367706514000455	0.545711749095962	0.5852640944024592	1.0	1.0	4	P40855	1
Downregulation of erbb2 signaling	0.4568186185429252	0.5405031991156626	0.5888500553630069	1.0	1.0	6	Q9UNE7,Q16543	2
Synthesis of bile acids and bile salts via 7alpha hydroxycholesterol	0.6457840578658676	0.5371105220803233	0.5911912730806672	1.0	1.0	3	P22307	1
Signaling by ntrk2 trkb	0.6334559567520636	0.5349822332140081	0.592662142931544	1.0	1.0	4	P63000	1
Phosphorylation of emi1	0.6429685063922657	0.5278959414673288	0.5975715617704584	1.0	1.0	3	P06493,P53350	2
Global genome nucleotide excision repair gg ner	0.2911032358848123	0.5209710222842115	0.6023869580457706	1.0	1.0	41	P27694,P56282,Q9H981,P25490,P23025,Q9BT78,P15927,P18858,Q13098	9
Tp53 regulates transcription of genes involved in g2 cell cycle arrest	0.4096700416079531	0.5205021279210389	0.602713645153262	1.0	1.0	9	Q99873,Q86X55,P04637	3
Pentose phosphate pathway	0.421431629724418	0.5196363712776227	0.6033170428256551	1.0	1.0	8	P60891,Q96G03,P29401,P37837	4
Transcriptional regulation by runx2	0.2669957412810247	0.5085591239191537	0.6110612868119316	1.0	1.0	53	P06493,Q14997,P28482,P28072,P60900,P11802,O75832,P49841,P20618,P04150,P49721,Q92530,P62191	13
Atf4 activates genes in response to endoplasmic reticulum stress	0.3820944597602963	0.5049429489669155	0.6135989071322341	1.0	1.0	11	P08243	1
Oncogenic mapk signaling	0.3046001479898275	0.4977908861245772	0.6186314403707478	1.0	1.0	29	P30086,O95352,Q9NRY5,Q96PU8	4
Defective cftr causes cystic fibrosis	0.2852394093175176	0.4938283844453803	0.6214273852770589	1.0	1.0	43	Q14997,P28072,P60900,O75832,Q9GZP9,P20618,P49721,Q92530	8
Cytosolic iron sulfur cluster assembly	0.4448907165885968	0.4923406966696456	0.6224785149677969	1.0	1.0	6	O75027	1
Cytochrome c mediated apoptotic response	0.5151446089652388	0.4922304690012784	0.6225564272836603	1.0	1.0	5	P28482	1
Rho gtpases activate rocks	0.4021573840461205	0.485937675319589	0.6270113552690004	1.0	1.0	9	P61586	1
Leishmania infection	0.2820642018509152	0.4797325210652626	0.6314176001642307	1.0	1.0	44	P60953,Q92747,P28482,P09601,P63000,P63218,P46108,O15143,Q16539,P78536,Q9UQB8	11
Nuclear envelope ne reassembly	0.2829143802031664	0.4730041486791368	0.6362102193446066	1.0	1.0	43	P50402,Q8IXJ6,P42166,Q9BTX1,Q86XL3	5
Ddx58 ifih1 mediated induction of interferon alpha beta	0.3396724500781529	0.4727373409986249	0.6364005824587866	1.0	1.0	16	P09429,O15111,O94826,Q15366	4
Synthesis of pips at the er membrane	0.6243464278560854	0.4684495150582115	0.639463165816617	1.0	1.0	3	Q9NTJ5	1
Methionine salvage pathway	0.6110269477296864	0.4643387942802519	0.6424050337396405	1.0	1.0	4	Q13126	1
Egr2 and sox10 mediated initiation of schwann cell myelination	0.3972729989436621	0.4638287333066139	0.6427704554449438	1.0	1.0	9	Q9NR77,Q16850	2
Bbsome mediated cargo targeting to cilium	0.4205432407118241	0.4525357755003187	0.6508830544700603	1.0	1.0	7	P50990,P78371,P48643,P49368,Q9H0F7,P17987	6
Dap12 signaling	0.6184459710609445	0.4501908626439316	0.6525728242280415	1.0	1.0	3	P63000	1
Downstream signaling of activated fgfr3	0.6180551503656958	0.4489918221434518	0.6534375559795622	1.0	1.0	3	Q06124	1
Downstream signaling of activated fgfr2	0.6180551503656958	0.4489918221434518	0.6534375559795622	1.0	1.0	3	Q06124	1
Downstream signaling of activated fgfr1	0.6180551503656958	0.4489918221434518	0.6534375559795622	1.0	1.0	3	Q06124	1
Downstream signaling of activated fgfr4	0.6180551503656958	0.4489918221434518	0.6534375559795622	1.0	1.0	3	Q06124	1
Regulation of tp53 activity	0.2655024041066886	0.4428612856401061	0.6578660714254374	1.0	1.0	50	Q9Y5B9,O96017,Q8WXI9,P06493,Q13526,O14757,O14744,Q13535,P51530,P27694,Q9NPI1,Q16539,P67870,P40938,P04637,P15927	16
Translation of sars cov 1 structural proteins	0.4032140643771822	0.440416705151672	0.659635328054218	1.0	1.0	8	Q10472,P49840,P49841	3
Ca2 pathway	0.4305893122136399	0.4364767355049419	0.6624908749472995	1.0	1.0	6	Q9HCE1,P63218,O43318	3
Downregulation of erbb4 signaling	0.562967581047388	0.4354739861591323	0.6632184172955826	1.0	1.0	2	Q96J02	1
Signaling by alk in cancer	0.2910335164786336	0.4353276637416723	0.6633246077512143	1.0	1.0	33	Q9HC35,Q63HN8,P28482,Q07866,P62753,O94979,Q13501,P06753,Q86WB0	9
Abc transporter disorders	0.2751973998194227	0.4334348875699104	0.6646988597815977	1.0	1.0	45	Q14997,P28072,P60900,O75832,Q9GZP9,P20618,P49721,Q92530	8
Glycosphingolipid metabolism	0.3265700602826621	0.4214642538403773	0.6734161083866386	1.0	1.0	17	O43681,Q13510,P04062,Q16739	4
Negative regulation of mapk pathway	0.3433769000024785	0.4211640978892482	0.6736352587321717	1.0	1.0	13	P28482,P30086,Q16537	3
Nade modulates death signalling	0.6075648291711038	0.4173036557678823	0.6764563148647222	1.0	1.0	3	P42575	1
Uptake and function of diphtheria toxin	0.5943037099503277	0.4141126223311405	0.6787916291827931	1.0	1.0	4	P13639	1
Sema4d mediated inhibition of cell attachment and migration	0.604136002299998	0.4071595076167579	0.6838908395777139	1.0	1.0	3	P61586	1
Formation of xylulose 5 phosphate	0.6040620771100434	0.4069419890662268	0.6840505955737679	1.0	1.0	3	P14550	1
Stabilization of p53	0.2789212455740821	0.3994502713275568	0.689561458589609	1.0	1.0	39	O96017,Q14997,P28072,P60900,O75832,P20618,P04637,P49721,Q92530,P62191	10
Transcriptional regulation by tp53	0.2587801377880711	0.3959975914968074	0.692106805009221	1.0	1.0	120	O14757,P53611,Q8IXH7,P42575,Q9HCE1,P67870,P15927,Q9NZN8,Q99873,Q8WXI9,Q16539,Q14004,P00403,P04637,Q04917,P14854,Q13535,P18615,Q14241,Q9NQ88,Q8WX92,P13073,Q86X55	23
Insulin receptor signalling cascade	0.4180399146353211	0.3893646457995225	0.6970064211829197	1.0	1.0	6	P28482	1
Tgf beta receptor signaling activates smads	0.3687214275125957	0.3874144481018987	0.698449409298048	1.0	1.0	10	P62136,Q9Y3F4,Q9Y4E8	3
Activation of gene expression by srebf srebp	0.3058315442553013	0.3859995204114667	0.6994970239902649	1.0	1.0	21	Q14534,O75845,Q16850,Q86X55,O00767	5
Recognition of dna damage by pcna containing replication complex	0.3112863515127607	0.3826264387385826	0.7019967641232796	1.0	1.0	19	P56282,O94782,P15927,P27694	4
Translesion synthesis by polk	0.3783429202970088	0.3811802347451158	0.7030695143773382	1.0	1.0	9	P15927,P27694	2
Auf1 hnrnp d0 binds and destabilizes mrna	0.2731320993933397	0.377260446311185	0.705980063447526	1.0	1.0	42	Q14103,Q14997,P28072,P60900,O75832,P20618,P11940,P49721,Q92530	9
Mapk3 erk1 activation	0.5809518665510672	0.3756851131425134	0.7071510065179649	1.0	1.0	4	P06493	1
P75 ntr receptor mediated signalling	0.3022185341483343	0.3636774578881291	0.7160988783382414	1.0	1.0	21	P42575,Q9NQC3,P61586,P78536	4
Metabolism of nucleotides	0.2585996185342631	0.356339878405917	0.721586048073243	1.0	1.0	49	Q9H773,Q9NRF8,P35754,P49902,Q06203,Q02127,P17812,Q9Y3Z3,P30520,P23921,Q16881,P55263,P00390,P04818,Q9H0P0	15
Rhog gtpase cycle	0.2738223747337771	0.353472572772188	0.7237341871436827	1.0	1.0	38	O15498,P50402,P42166,O15173,Q86XL3	5
Er quality control compartment erqc	0.5714443738820867	0.3492975534881635	0.7268659349606357	1.0	1.0	4	Q9GZP9	1
Tnfr2 non canonical nf kb pathway	0.2691798615432195	0.3450946398103935	0.7300232230288415	1.0	1.0	42	O15111,Q14997,P28072,P60900,O75832,P20618,P49721,Q92530	8
Dectin 1 mediated noncanonical nf kb signaling	0.2691798615432195	0.3450946398103935	0.7300232230288415	1.0	1.0	42	O15111,Q14997,P28072,P60900,O75832,P20618,P49721,Q92530	8
Mismatch repair	0.3336712947999441	0.3436178848745316	0.731133672674122	1.0	1.0	12	P20585,P15927,P18858,P27694	4
Negative regulation of fgfr1 signaling	0.4052284736050843	0.3433286621410382	0.7313512205172787	1.0	1.0	6	P28482	1
Negative regulation of fgfr2 signaling	0.4052284736050843	0.3433286621410382	0.7313512205172787	1.0	1.0	6	P28482	1
Spry regulation of fgf signaling	0.4052284736050843	0.3433286621410382	0.7313512205172787	1.0	1.0	6	P28482	1
Negative regulation of fgfr3 signaling	0.4052284736050843	0.3433286621410382	0.7313512205172787	1.0	1.0	6	P28482	1
Negative regulation of fgfr4 signaling	0.4052284736050843	0.3433286621410382	0.7313512205172787	1.0	1.0	6	P28482	1
Signaling by vegf	0.2875334549460145	0.3374374560046812	0.7357871528223745	1.0	1.0	26	P61586,P46108,Q9UQB8	3
Response to elevated platelet cytosolic ca2	0.2806857987381397	0.3321642218431107	0.7397652582587422	1.0	1.0	30	P37802,Q6UXV4,O75083,Q9NTK5,Q9NUQ9,Q9UNF1,Q01518,P04075,Q8NBX0,Q92520,P07602,O43707,O43852,O94919,Q9NZJ7	15
Regulation of lipid metabolism by pparalpha	0.2896919960657166	0.3274081722714891	0.7433591862100204	1.0	1.0	23	O75376,Q15067,P23786,Q86X55	4
Interleukin 12 family signaling	0.27976656673326	0.3259106838316364	0.7444919321317918	1.0	1.0	30	P52597,Q99439,Q13126,O00170,P07237,O14979,P22626,Q9H3K6	8
Signaling by interleukins	0.2449473401658145	0.3234290978219671	0.7463702958300924	1.0	1.0	111	Q99439,P28482,P22626,O75832,Q06124,Q13126,O15111,P09601,P60900,P46108,P27824,Q13501,P49721,P62191,P60953,P28066,P04083,O00170,P07237,Q16658,P28072,Q16539,P20618,P04637,P42574,Q92530,P52597,Q14997,O14979,P09429,Q9H3K6	31
Toll like receptor tlr1 tlr2 cascade	0.2948951750037969	0.3197071484129589	0.7491903403348126	1.0	1.0	21	P09429,O15111	2
Prolactin receptor signaling	0.5723378210888663	0.3185210934940989	0.7500896968891904	1.0	1.0	3	Q06124	1
The role of gtse1 in g2 m progression after g2 checkpoint	0.2575421663871092	0.3119857478687585	0.7550513546903923	1.0	1.0	47	P06493,Q14997,P28072,P60900,O75832,Q92530,P20618,P04637,P49721,O95067,P62191	11
Rnd1 gtpase cycle	0.3207389532523276	0.3098285806649385	0.7566913161167594	1.0	1.0	13	P51648	1
Rac2 gtpase cycle	0.267229088939976	0.2980086013534441	0.7656965988043911	1.0	1.0	36	Q13505,Q86Y07,P50402,P42166,Q14739,O15173,Q86XL3	7
Metabolism of cofactors	0.4526347171365575	0.2883808490935035	0.7730552255515799	1.0	1.0	5	P00374	1
Interleukin 1 family signaling	0.2461175452224416	0.287025280909009	0.7740929629255195	1.0	1.0	51	O15111,Q14997,P28072,P09429,P60900,O75832,Q06124,P20618,Q13501,P49721,Q92530,P62191	12
Switching of origins to a post replicative state	0.2457136702509612	0.2810229350919772	0.7786928087321892	1.0	1.0	59	P20618,Q9UBD5,Q14997,P28072,P60900,P49721,O75832,Q14566,Q9Y619,Q92530,P62191	11
Inactivation of cdc42 and rac1	0.5554121258054187	0.2756826429060373	0.7827918281614681	1.0	1.0	3	P60953	1
Dna replication pre initiation	0.245556718153075	0.2710463774131657	0.7863553628148607	1.0	1.0	67	P20618,Q9UBD5,Q14997,P28072,P60900,P49721,P56282,O75832,Q7L590,Q14566,Q9Y619,Q92530,P15927,O00311	14
Regulation of bach1 activity	0.5528485211476153	0.2694759798564085	0.7875634240721889	1.0	1.0	3	Q13309	1
Piwi interacting rna pirna biogenesis	0.3698916156534887	0.2639481664886057	0.7918198597911925	1.0	1.0	7	Q8N2A8	1
Rho gtpases activate paks	0.3148267164700086	0.2593323730704773	0.7953788034642253	1.0	1.0	12	P60953,P60660,P63000	3
Metabolism of polyamines	0.2597348099282621	0.2538246967499638	0.799630992885092	1.0	1.0	39	P19623,Q14997,P28072,P60900,O75832,P20618,P49721,Q92530	8
Ctla4 inhibitory signaling	0.3547782635852551	0.2525181987141802	0.800640549250691	1.0	1.0	8	P30154,Q16537,Q14738,Q06124,P07948,P30153,P31751	7
Small interfering rna sirna biogenesis	0.5441222326161392	0.248922256035143	0.8034209192232835	1.0	1.0	3	Q15631,Q99598	2
Regulation of mecp2 expression and activity	0.3062943607473626	0.245235473272373	0.8062741111179701	1.0	1.0	13	Q14739,Q9HCE1	2
Toll like receptor 9 tlr9 cascade	0.2786709807564138	0.2440035386936657	0.8072280792607083	1.0	1.0	22	P09429,O15111	2
Nuclear receptor transcription pathway	0.5295205036489496	0.2436941978547531	0.807467667364776	1.0	1.0	4	O75376	1
Synthesis of dna	0.2361089157899759	0.241485190551691	0.8091790931345675	1.0	1.0	85	O75832,P18858,Q9UBD5,P60900,P27694,P49642,Q14566,P49721,Q9Y619,P15927,Q9UJX4,P62191,P28066,O43913,P28072,Q9H1A4,P20618,P40938,Q92530,Q14997,Q14181,P51530,P39748,P56282	24
Iron uptake and transport	0.2895065271077389	0.2414814775580682	0.8091819705429006	1.0	1.0	18	P30519	1
Regulation of pten localization	0.5394512570662153	0.2382901349557138	0.8116560721772925	1.0	1.0	3	Q93009	1
Metabolism of lipids	0.3007063699907877	0.2298539302056405	0.8182052762033787	1.0	1.0	191	Q8N2A8,Q14534,Q16850,P33527,Q06136,Q9NQZ5,Q9H7Z7,O95470,Q96N66,Q8NF37,O75845,P27544,P40939,Q10713,Q16739,Q96G23,Q13510,P67870,Q15800,Q14739,Q15067,O00767,P23786,O43772,P62136,P04062,P38435,Q08426,P35610,P07602,P30536,Q14914,Q15392,P51648,O43681,O15254,O15121,O75376,Q9P035,Q15185,Q86X55	41
Caspase activation via extrinsic apoptotic signalling pathway	0.5224359599127878	0.2277214926277815	0.8198627626855588	1.0	1.0	4	P42574,Q9UKG1	2
Activation of the mrna upon binding of the cap binding complex and eifs and subsequent binding to 43s	0.2363774609018164	0.2252353776695002	0.8217961690377149	1.0	1.0	52	Q13347,O75822,P62266,P62753,P25398,P62273,P62263,P11940,P46782,P15880	10
Regulation of pten stability and activity	0.2508088058331218	0.223593834808303	0.82307336133589	1.0	1.0	44	Q14997,P28072,P60900,O75832,P67870,P20618,P49721,Q92530	8
Cooperation of prefoldin and tric cct in actin and tubulin folding	0.2965152288150506	0.223106873244961	0.823452329098443	1.0	1.0	14	P61758	1
Nuclear signaling by erbb4	0.4279761614114526	0.2211121729600006	0.8250050921774958	1.0	1.0	5	P78536	1
Deadenylation dependent mrna decay	0.2544516441644157	0.2175427456820699	0.8277853982826016	1.0	1.0	39	Q9NZN8,Q6PGP7	2
Cellular response to hypoxia	0.253724251008153	0.2167955208557003	0.8283677027909921	1.0	1.0	40	Q9GZT9,Q14997,P28072,P60900,O75832,P20618,P49721,Q92530,P62191	9
Fc epsilon receptor fceri signaling	0.23559795664664	0.2146309718854555	0.8300550445565495	1.0	1.0	53	O15111,Q14997,P28482,P63000,P28072,P60900,O75832,P20618,P49721,Q92530,P62191	11
Signaling by fgfr4	0.3543552919138212	0.2143775980493747	0.8302526097477232	1.0	1.0	7	P28482,P22681,Q06124,P19174,P62993,P30153	6
Signaling by fgfr1	0.3543552919138212	0.2143775980493747	0.8302526097477232	1.0	1.0	7	P28482,P22681,Q06124,P19174,P62993,P30153	6
Signaling by fgfr3	0.3543552919138212	0.2143775980493747	0.8302526097477232	1.0	1.0	7	P28482,P22681,Q06124,P19174,P62993,P30153	6
Gap filling dna repair synthesis and ligation in gg ner	0.2801709262728902	0.2126987881220985	0.8315619120754623	1.0	1.0	19	P56282,P15927,P18858,P27694	4
Downstream signaling events of b cell receptor bcr	0.24967772586801	0.2073328886724296	0.8357498906948719	1.0	1.0	43	O15111,Q14997,P28072,P60900,O75832,P20618,P49721,Q92530	8
Signaling by hedgehog	0.2359613894234695	0.2064260630145457	0.83645811387416	1.0	1.0	56	Q14997,P07237,P28072,P60900,O75832,Q9GZP9,P78536,P20618,P49721,Q92530,P62191	11
Linoleic acid la metabolism	0.5240522423874212	0.2051094436409573	0.8374866183324348	1.0	1.0	3	O95864	1
Pi5p regulates tp53 acetylation	0.5238450702762608	0.2046828933524813	0.8378198865719584	1.0	1.0	3	P04637	1
Regulation of cholesterol biosynthesis by srebp srebf	0.2640471174415318	0.2035269440960728	0.8387231880292967	1.0	1.0	27	Q14534,O75845,Q16850,Q86X55,O00767	5
Synthesis of udp n acetyl glucosamine	0.5229641441818824	0.2028750822471774	0.8392326707591287	1.0	1.0	3	Q06210	1
Fceri mediated nf kb activation	0.2459165630027286	0.1981505069226334	0.8429273093629002	1.0	1.0	45	O15111,Q14997,P28072,P60900,O75832,P20618,P49721,Q92530	8
Copi dependent golgi to er retrograde traffic	0.2428450468461528	0.19753945539708	0.8434054087337115	1.0	1.0	47	Q07866,P62820,P24390,Q9Y3B3,O14579,O00139,O15260,Q9P2W9,Q12981	9
Diseases of signal transduction by growth factor receptors and second messengers	0.2645924791393299	0.1955351375964805	0.8449740327083197	1.0	1.0	148	Q9HC35,Q96PU8,P28482,P63000,Q16630,P49589,O75832,P30086,P06753,Q86WB0,Q63HN8,O15111,P62753,P60900,Q9UBW7,Q09161,Q6WCQ1,Q13501,Q9NRY5,P49721,P62191,P49840,P28072,Q13363,P20618,P49841,Q92530,Q16543,Q14997,Q07866,O95352,O75376,O94979,P78536,Q9GZP9	35
Constitutive signaling by aberrant pi3k in cancer	0.5062365316277354	0.1933749562465294	0.8466653272794629	1.0	1.0	4	P63000	1
Synthesis of substrates in n glycan biosythesis	0.289308655215264	0.193326125429093	0.8467035671250365	1.0	1.0	14	Q06210,Q9UJ70,Q8NFW8,Q9NR45	4
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane	0.4148088976615097	0.1887719494011581	0.850271557680607	1.0	1.0	5	Q99808	1
Regulation of mrna stability by proteins that bind au rich elements	0.2355857894816887	0.1886518311273358	0.8503657067556327	1.0	1.0	62	Q14103,Q14997,P28072,P60900,Q01105,O75832,Q16539,P20618,P11940,Q92945,P49721,Q92530	12
Ksrp khsrp binds and destabilizes mrna	0.2970683092171564	0.1882220455777378	0.8507025914647866	1.0	1.0	12	Q15024,Q9NPD3,Q9NQT5,Q16539,Q9Y2L1,Q92945	6
Golgi to er retrograde transport	0.2357262993511287	0.1868364289893954	0.8517888836076137	1.0	1.0	71	P68402,P63167,Q9UJW0,Q07866,Q8N6T3,P62820,P35606,P24390,Q13409,O14579,O00139,Q9Y3B3,O15260,Q9P2W9,P43034,Q12981,Q10472	17
Glyoxylate metabolism and glycine degradation	0.2902829982717704	0.1804758826134499	0.8567789863967279	1.0	1.0	13	P11182	1
Activated tak1 mediates p38 mapk activation	0.4989564146727163	0.1789480436935634	0.8579784981774967	1.0	1.0	4	Q16539	1
Negative regulation of the pi3k akt network	0.2941473886351784	0.1773754982276972	0.8592134517318448	1.0	1.0	12	P28482,P63000,Q16537,Q06124	4
Uch proteinases	0.2363542105239641	0.1760450276225523	0.8602585678901298	1.0	1.0	49	Q14997,P28072,P60900,O75832,Q9H981,P20618,P49721,Q92530,P25490,Q9Y4E8	10
Erythropoietin activates phospholipase c gamma plcg	0.4650872817955193	0.1691353619928932	0.8656901707528861	1.0	1.0	2	P19174	1
Golgi cisternae pericentriolar stack reorganization	0.2906545958257671	0.1647357780780096	0.8691519548552595	1.0	1.0	12	P62820,O95067,P06493	3
Interleukin 17 signaling	0.2727615090899533	0.1638900071944545	0.8698177338360034	1.0	1.0	18	P63208,O15111,O43318,P28482,Q16539	5
Semaphorin interactions	0.2748958551107632	0.1625199608022955	0.870896410781826	1.0	1.0	17	P60660,P49841,P61586	3
Cross presentation of soluble exogenous antigens endosomes	0.2461962611040337	0.1608082424557283	0.8722444331885877	1.0	1.0	37	Q14997,P28072,P60900,O75832,P20618,P49721,Q92530	7
Degradation of axin	0.2461962611040337	0.1608082424557283	0.8722444331885877	1.0	1.0	37	Q14997,P28072,P60900,O75832,P20618,P49721,Q92530	7
Tp53 regulates metabolic genes	0.2459306077477401	0.1500368918058072	0.8807355092303131	1.0	1.0	35	P14854,Q9HCE1,Q9NQ88,P13073,P00403,P04637,Q04917	7
Antigen processing cross presentation	0.225641335339451	0.139258392178638	0.8892459676752142	1.0	1.0	53	P10321,O15111,Q14997,P28072,P09429,P60900,P04439,O75832,Q92530,P20618,P49721,Q9UIQ6	12
Galactose catabolism	0.448254364089784	0.1382945278816786	0.8900076500748122	1.0	1.0	2	Q96G03	1
Rac1 gtpase cycle	0.2376608113120901	0.135823932550368	0.89196047094613	1.0	1.0	44	O15498,P50402,P42166,Q14739,Q9UQB8,P63167	6
Fbxw7 mutants and notch1 in cancer	0.4466957605985122	0.1356695735769389	0.8920825020475658	1.0	1.0	2	P63208	1
Degradation of dvl	0.2415994442516705	0.1352980087165102	0.8923762594169624	1.0	1.0	38	Q14997,P28072,P60900,O75832,P20618,P49721,Q92530	7
Scf skp2 mediated degradation of p27 p21	0.2401996682652299	0.1352898249377611	0.8923827296389557	1.0	1.0	41	P28072,P60900,P11802,O75832,P20618,P49721,Q92530	7
Polo like kinase mediated events	0.333710302991515	0.1339835438030734	0.8934155872400456	1.0	1.0	6	Q99640,O95067,Q5TKA1	3
Flt3 signaling	0.3868954758190268	0.1289990053513534	0.897358435867984	1.0	1.0	5	Q06124,P62993,P31751,P41240	4
Infection with mycobacterium tuberculosis	0.2695652757659282	0.1276237889263909	0.8984467042375692	1.0	1.0	15	P28482,P49840,Q63HN8,P00558	4
Response of mtb to phagocytosis	0.2695652757659282	0.1276237889263909	0.8984467042375692	1.0	1.0	15	P28482,P49840,Q63HN8,P00558	4
Formation of incision complex in gg ner	0.269501220889927	0.1273995946201434	0.8986241370727535	1.0	1.0	15	Q86WJ1,P54725,P27694,P23025,P15927,P09874	6
Tp53 regulates transcription of cell cycle genes	0.2659785168618754	0.1272002444446086	0.8987819119146412	1.0	1.0	17	Q9NZN8,Q99873,Q86X55	3
Enos activation	0.4767695665731126	0.1217428522909036	0.90310267441145	1.0	1.0	3	P35270,O75608	2
Regulation of runx2 expression and activity	0.2349628628945675	0.1195427358887948	0.9048453844164056	1.0	1.0	44	Q14997,P28072,P60900,O75832,P20618,P04150,P49721,Q92530,P62191	9
Oas antiviral response	0.4742750233863301	0.1181258073018366	0.9059679753361743	1.0	1.0	3	P21333,P61221	2
Clec7a dectin 1 signaling	0.2292528739041383	0.1168162787508536	0.9070056434958532	1.0	1.0	48	O15111,Q14997,P28072,P60900,O75832,P20618,P49721,Q92530	8
Apoptotic factor mediated response	0.317827037152662	0.1163259973123139	0.9073941825976825	1.0	1.0	7	P28482,Q9NR28,Q07021,P27361,P98170,P42574	6
Caspase activation via death receptors in the presence of ligand	0.433603491271829	0.115138317119436	0.9083354891778406	1.0	1.0	2	P49327	1
Regulation by c flip	0.433603491271829	0.115138317119436	0.9083354891778406	1.0	1.0	2	P49327	1
Mastl facilitates mitotic progression	0.4615402150361136	0.1149165315861803	0.908511281593011	1.0	1.0	4	P30154,P06493	2
Signaling by the b cell receptor bcr	0.2299372279237141	0.1117255555885233	0.911041015758932	1.0	1.0	47	O15111,Q14997,P28072,P60900,O75832,P20618,P49721,Q92530	8
Hdr through mmej alt nhej	0.3156415860131066	0.1113326752366488	0.911352545367898	1.0	1.0	7	P49916,Q92878,P39748,P18887,P49959,P09874	6
Signaling by notch1 pest domain mutants in cancer	0.2933057923500033	0.1098302873161281	0.9125439705371572	1.0	1.0	10	P78536	1
Glycerophospholipid biosynthesis	0.2371751468194113	0.1029906641448761	0.9179703804843806	1.0	1.0	35	Q9NQZ5,Q8N2A8,Q96N66,Q8NF37,P40939	5
Eph ephrin signaling	0.2405806361809854	0.1015949055631506	0.9190782232985284	1.0	1.0	31	P61586,Q92747	2
Regulation of ras by gaps	0.2351017273732746	0.1011673605949214	0.9194176062242972	1.0	1.0	39	Q14997,P28072,P60900,O75832,P20618,P49721,Q92530	7
Keratinization	0.3176664687459533	0.0998801679999878	0.9204394612510772	1.0	1.0	6	P14923,Q14574,P15924	3
Formation of the cornified envelope	0.3176664687459533	0.0998801679999878	0.9204394612510772	1.0	1.0	6	P14923,Q14574,P15924	3
Nuclear events stimulated by alk signaling in cancer	0.2690761202207737	0.0949561891314721	0.9243496256260102	1.0	1.0	12	Q9HC35,P62753,Q86WB0	3
Gaba receptor activation	0.3150233116837386	0.0947440036225735	0.924518165322433	1.0	1.0	6	P63218,Q9Y639	2
Myd88 independent tlr4 cascade	0.2448797819252193	0.0921252658642607	0.9265985145524602	1.0	1.0	23	P28482,Q16539,O15111,P09429	4
Nucleotide excision repair	0.219318958782981	0.0879935265410019	0.9298818212575648	1.0	1.0	51	Q9UNP9,P27694,P56282,Q9H981,P25490,P23025,Q9BT78,P15927,P18858,Q13098	10
Cyclin a cdk2 associated events at s phase entry	0.2291906148871245	0.0820196159252833	0.934631114756922	1.0	1.0	43	P28072,P60900,P11802,O75832,P20618,P49721,Q92530	7
Folding of actin by cct tric	0.2945034353529004	0.0816708381205613	0.9349084686764556	1.0	1.0	8	P50990,P50991,P78371,P48643,P49368,Q99832,P17987	7
Glycogen metabolism	0.2804978995003877	0.0764448415432101	0.9390651955596758	1.0	1.0	10	P35573,P46976,P46020	3
Snrnp assembly	0.2298501247907554	0.0743965819379688	0.9406948284864808	1.0	1.0	39	Q9BTX1,Q09161,Q16637,Q9NWZ8	4
Degradation of beta catenin by the destruction complex	0.2164953221106423	0.0712190747269157	0.943223400526784	1.0	1.0	51	Q14997,Q04726,P28072,P60900,O75832,Q13363,P20618,P49841,P49721,Q92530,P62191	11
Netrin 1 signaling	0.2776747926100048	0.0696799719877159	0.9444483830672524	1.0	1.0	10	P60953,P63000,Q16539	3
Pi metabolism	0.2484166768742589	0.0618712201521982	0.9506653865657856	1.0	1.0	15	Q9UBF8,Q9NTJ5,Q10713,Q9BTU6,Q01968	5
Gastrin creb signalling pathway via pkc and mapk	0.3444617784711343	0.0615399164834926	0.950929225874082	1.0	1.0	5	P28482,P51812,P27361,P62993	4
Asymmetric localization of pcp proteins	0.2272469741828665	0.0611430224981548	0.9512453062256732	1.0	1.0	38	Q14997,P28072,P60900,O75832,P20618,P49721,Q92530	7
Dna damage reversal	0.3432137285491364	0.0599733608417366	0.9521768514572916	1.0	1.0	5	Q9H1I8,Q8N9N2,Q8N3C0,Q6P6C2	4
Rhod gtpase cycle	0.2326256160313611	0.0583464394845792	0.9534726771357556	1.0	1.0	28	P42166,O15173,P50402	3
Degradation of the extracellular matrix	0.2651009847090875	0.0567323712261952	0.9547583870239388	1.0	1.0	11	P35613	1
Tcr signaling	0.2199123369090996	0.0555665537847804	0.9556871095335304	1.0	1.0	47	O15111,Q14997,P28072,P60900,O75832,P20618,P49721,Q92530	8
Phase 0 rapid depolarisation	0.3756234413965159	0.0541246267357909	0.9568358717038364	1.0	1.0	2	Q13557	1
Sars cov 1 infection	0.2490562702916128	0.0515296166896229	0.9589035024881152	1.0	1.0	13	Q10472,P49840,P49841,Q14457	4
Telomere c strand lagging strand synthesis	0.2357466716246966	0.0495798292131149	0.9604572208163912	1.0	1.0	22	P18858,Q14181,P51530,P27694,P39748,P40938,P15927	7
G0 and early g1	0.2869546879147454	0.048510211476975	0.9613096264424592	1.0	1.0	6	P06493,Q5TKA1	2
Josephin domain dubs	0.4044278141565313	0.0462410827754691	0.9631180981591734	1.0	1.0	3	P54727,P54725	2
Phospholipid metabolism	0.2152495419351451	0.0459956816110147	0.9633136918437536	1.0	1.0	49	Q9UG56,Q8N2A8,Q96N66,Q9BVG9,Q8NF37,Q9NQZ5,O96017,Q9UBF8,Q9NTJ5,P40939,Q10713,Q8IV08,P67870,Q9BTU6,Q01968,O75131,Q9NP80,Q8NCC3	18
Antigen presentation folding assembly and peptide loading of class i mhc	0.2410104480297318	0.0433024194450328	0.96546046259496	1.0	1.0	16	P10321,O95486,P01889,P04439,O94979,P27824,O95487,P53992	8
Signaling by tgf beta receptor complex	0.2360692338401409	0.041102250685394	0.9672143803340671	1.0	1.0	20	P61586,P62136,O75376	3
Ion channel transport	0.2290247547686394	0.0408833910035582	0.9673888584357428	1.0	1.0	27	P23634,P16615,Q9HD20	3
Thrombin signalling through proteinase activated receptors pars	0.3261638627661318	0.0408155572070457	0.9674429368360826	1.0	1.0	5	P28482,P63218	2
Rho gtpases activate formins	0.2132272654390793	0.0406255611320527	0.9675944061381652	1.0	1.0	60	P60953,P61586,P63167,O43684,Q53HL2,O75122,P63000,P35080,O00139,Q9P258,P43034,Q8NBT2	12
Transcriptional activity of smad2 smad3 smad4 heterotrimer	0.2686249870646482	0.0334758203424712	0.97329514759389	1.0	1.0	8	P28482,O75376	2
Pp2a mediated dephosphorylation of key metabolic factors	0.3638914873713731	0.0260971446837832	0.9791798545006408	1.0	1.0	3	Q14738,P30154	2
Dna replication	0.2055226857721904	0.0260106525701104	0.9792488418042912	1.0	1.0	92	O75832,Q7L590,P18858,Q9UBD5,P60900,P27694,P49642,Q14566,P49721,Q9Y619,P15927,Q9UJX4,P62191,O00311,P28066,O43913,P28072,Q9H1A4,P20618,P40938,Q92530,Q14997,Q14181,P51530,P39748,P56282	26
Signaling by tgfb family members	0.2298745751849093	0.025874409367022	0.979357511578123	1.0	1.0	21	P61586,P62136,O75376	3
Runx2 regulates osteoblast differentiation	0.353913314624259	0.0228930304418586	0.9817355998418632	1.0	1.0	3	P28482,P07947	2
Copi independent golgi to er retrograde traffic	0.2245078320646416	0.0225610461673118	0.9820004165675668	1.0	1.0	26	Q9UJW0,Q13409,Q10472,P43034,P68402,P63167	6
C type lectin receptors clrs	0.2071784480368332	0.0219164580624978	0.9825145962929528	1.0	1.0	51	O15111,Q14997,P28072,P60900,O75832,P20618,P49721,Q92530	8
Sema3a pak dependent axon repulsion	0.302964118564738	0.0209887079847888	0.9832546634157376	1.0	1.0	5	P07900,P63000,Q13177,P08238	4
Pecam1 interactions	0.3543356207111736	0.0184624822625671	0.985269907277904	1.0	1.0	4	Q06124,P19174,P07948	3
Runx2 regulates bone development	0.3540237055520959	0.0183341869362836	0.985372254814178	1.0	1.0	4	P28482,P07947,Q96PK6	3
Nef mediated downregulation of mhc class i complex cell surface expression	0.2942555279733128	0.0152078368871118	0.9878663694539478	1.0	1.0	5	P04439	1
Rsk activation	0.3443543356207167	0.0146749046927307	0.9882915403575736	1.0	1.0	4	P28482,P51812,P27361	3
Formyl peptide receptors bind formyl peptides and many other ligands	0.3068953131586339	0.0140858651617395	0.9887614773053326	1.0	1.0	3	P04083	1
Synthesis of diphthamide eef2	0.2881197380729678	0.0125287943036225	0.9900037299805772	1.0	1.0	3	P13639,Q9H2P9	2
Thromboxane signalling through tp receptor	0.2860261923439107	0.0123994252664193	0.9901069435203044	1.0	1.0	3	P63218	1
Jnk c jun kinases phosphorylation and activation mediated by activated human tak1	0.2609915809167515	0.0113430896512475	0.9909497179726692	1.0	1.0	3	Q15750,O43318	2
Metabolism of ingested semet sec mesec into h2se	0.2516370439663303	0.0111212035039938	0.9911267463360556	1.0	1.0	3	P23526,Q96I15	2
Signaling by notch1	0.2326016140187088	0.010702618465855	0.9914607089899063	1.0	1.0	12	P78536	1
Dna strand elongation	0.217994159448863	0.0067638523373976	0.9946032677982832	1.0	1.0	28	P18858,Q14181,P51530,P27694,P39748,Q14566,P40938,P15927	8
Role of phospholipids in phagocytosis	0.3059921557899634	0.0052058101384964	0.9958463832248514	1.0	1.0	4	Q8IV08,O43865	2
Estrogen dependent nuclear events downstream of esr membrane signaling	0.2947598253275155	0.0036013879554308	0.9971265143644176	1.0	1.0	4	P28482,P27361,P31751	3
Homologous dna pairing and strand exchange	0.2232101088922307	0.0035248913499877	0.9971875494373889	1.0	1.0	19	O14757,Q13535,P51530,P27694,P15927	5
Miro gtpase cycle	0.2645059095732769	0.0011212099482827	0.9991054040802811	1.0	1.0	5	Q8IWA4	1
Metabolic disorders of biological oxidation enzymes	0.262320648783533	0.0008501096140141	0.9993217107456864	1.0	1.0	4	P22570,P48506,P23526	3
Vitamin b5 pantothenate metabolism	0.2633385335413373	0.0007218223575202	0.9994240691353048	1.0	1.0	5	Q9NVE7,Q9NRN7,Q13057,P49327	4