| Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size |
| Sphingolipid metabolism overview 0.8837870784234074 2.537283140003489 0.0111716558908117 0.9985694975750916 0.9159908246364205 7 Q16739,O15121,Q96G23,Q13510,O15269,O95470 6 |
| Sphingolipid metabolism integrated pathway 0.8837870784234074 2.537283140003489 0.0111716558908117 0.9985694975750916 0.9159908246364205 7 Q16739,O15121,Q96G23,Q13510,O15269,O95470 6 |
| Sphingolipid pathway 0.8230956334478918 2.262400043824309 0.0236726982315995 0.999999140713456 0.9159908246364205 8 Q16739,Q96G23,Q13510,O15269,O95470,P04062 6 |
| Degradation pathway of sphingolipids including diseases 0.8443433478111121 2.253796383988235 0.0242089804085212 0.9999993762303386 0.9159908246364205 6 P17900,P06280,P16278,P06865 4 |
| Sphingolipid metabolism in senescence 0.8244936941067941 2.189320674710195 0.0285735406928953 0.9999999542924152 0.9159908246364205 12 Q16739,O15121,Q96G23,Q13510,P24941,O15269,P04062,P16278 8 |
| Glycosaminoglycan degradation 0.8781973203410393 2.1875445056078213 0.0287027979524956 0.9999999577042944 0.9159908246364205 5 P06865,P15586,P16278,P54802 4 |
| Mitochondrial complex iii assembly 0.7946840671077677 2.1400630811753905 0.0323496691764209 0.9999999952809344 0.9159908246364205 8 Q6DKK2,Q9UDW1,O14949 3 |
| Statin inhibition of cholesterol production 0.908346401056326 2.1128329826647803 0.0346150655743195 0.9999999987966236 0.9159908246364205 4 Q14534,Q8WTV0 2 |
| Metabolism of spingolipids in er and golgi apparatus 0.882711038961048 2.0089068930366945 0.0445470087784212 0.9999999999971024 0.9159908246364205 4 Q16739,O95470,Q10472 3 |
| Mitochondrial complex iv assembly 0.7647051397186285 1.948656539197343 0.0513364552269195 0.9999999999999548 0.9159908246364205 11 P00403,Q9Y2R0,P13073,Q9Y241,P14406 5 |
| Familial partial lipodystrophy fpld 0.7669932815666545 1.921127622280126 0.0547156200217069 0.9999999999999944 0.9159908246364205 6 O75844,O60725 2 |
| Oxidation by cytochrome p450 0.7921632415332187 1.826070942793918 0.06783957642734 1.0 0.9159908246364205 5 O43169,Q16850 2 |
| Striated muscle contraction pathway 0.8035714285714404 1.68186502020382 0.0925950170217779 1.0 1.0 4 P06753,P67936,P08670 3 |
| Endothelin pathways 0.6832711430450098 1.6423175848810012 0.1005242046628498 1.0 1.0 8 P00403,P42892 2 |
| Influence of laminopathies on wnt signaling 0.6865302193555679 1.616509598752727 0.1059841797762426 1.0 1.0 10 P02545,O60725,O75844 3 |
| Overlap between signal transduction pathways contributing to lmna laminopathies 0.7038885158195844 1.616126813895007 0.106066897962755 1.0 1.0 14 P42167,P50402,P02545,O60725,O75844,P55209 6 |
| Acquired partial lipodystrophy barraquersimons syndrome 0.7696387216720435 1.5391645250674175 0.1237641357222345 1.0 1.0 4 O60725 1 |
| Vitamin a and carotenoid metabolism 0.7173653825910841 1.5017090319009108 0.1331722703033413 1.0 1.0 5 Q6NUM9,Q8WTV0 2 |
| Ccl18 signaling pathway 0.6488366706491067 1.4624948062237932 0.1436056665727021 1.0 1.0 9 P00403,P08670,P42224,Q96GC9,Q86UE4 5 |
| S1p receptor signal transduction 0.6305321492216248 1.4179587524025654 0.156202807593297 1.0 1.0 7 P27361,Q13510,P04899,P28482,Q9H0H5 5 |
| Proteoglycan biosynthesis 0.959448499594484 1.253261473110847 0.2101105645761949 1.0 1.0 2 Q8NCH0 1 |
| Progeriaassociated lipodystrophy 0.6030414196648741 1.247339122498323 0.212273178167403 1.0 1.0 9 O75844,O60725 2 |
| Cholesterol biosynthesis with skeletal dysplasias 0.6458153289945954 1.1854123604582267 0.2358544469939085 1.0 1.0 5 Q15392,Q16850 2 |
| Ketogenesis and ketolysis 0.6034670834183138 1.1802106304376594 0.2379164520690826 1.0 1.0 6 P53985,O43772 2 |
| Disruption of postsynaptic signaling by cnv 0.6025979468752141 1.1761790110624029 0.2395233499169182 1.0 1.0 6 P28482,Q14168,P27361 3 |
| Tgfbeta signaling in thyroid cells for epithelialmesenchymal transition 0.6720661501322055 1.1245666522066262 0.2607727115909004 1.0 1.0 4 P08670,P27361 2 |
| Tgfbeta receptor signaling 0.6291029111596976 1.1112238853175938 0.2664719925278391 1.0 1.0 5 P42224,P62942,P27361 3 |
| Tgfbeta receptor signaling in skeletal dysplasias 0.6291029111596976 1.1112238853175938 0.2664719925278391 1.0 1.0 5 P42224,P62942,P27361 3 |
| Kennedy pathway from sphingolipids 0.9213300892132994 1.1103675873583585 0.2668406594068382 1.0 1.0 2 O95470 1 |
| Proximal tubule transport 0.5738047935021812 1.1085903178446364 0.2676069568405945 1.0 1.0 9 P08183,P05023,P04920 3 |
| Il17 signaling pathway 0.6595725990981534 1.071526098916202 0.2839329420771908 1.0 1.0 4 P28482,P27361 2 |
| Ferroptosis 0.5938650169055408 0.9908118282362276 0.3217774725059117 1.0 1.0 20 P45880,Q9NZ45,P09601,P37268,Q9Y277 5 |
| Mammary gland development pathway pregnancy and lactation stage 3 of 4 0.7699797160243372 0.9796056599428103 0.3272808100047195 1.0 1.0 3 P06753,P18031 2 |
| Allograft rejection 0.5369022272757853 0.9527436352912738 0.3407199788147335 1.0 1.0 8 P08670,P04439,P08183,P10321 4 |
| Metapathway biotransformation phase i and ii 0.5767870467973847 0.948133098401758 0.3430617002835014 1.0 1.0 18 P07099,P21964,O14880,Q7LGA3,P21266,Q8NCH0,P00390,Q16850 8 |
| Bile acids synthesis and enterohepatic circulation 0.7405638412072062 0.8664890197655084 0.3862220452372318 1.0 1.0 3 P27361 1 |
| Urea cycle and related diseases 0.852392538523923 0.8583843730307753 0.3906802536611398 1.0 1.0 2 Q9UJS0 1 |
| Regulatory circuits of the stat3 signaling pathway 0.5309442626148209 0.8442120028863048 0.3985509484810281 1.0 1.0 6 P40763,P28482,P27361,P16949 4 |
| Vitamin d metabolism 0.733062880324536 0.8380149555934466 0.4020223040526272 1.0 1.0 3 P38435,P04062 2 |
| Copper homeostasis 0.5040568537971729 0.8160699258980196 0.4144601433623827 1.0 1.0 7 Q8N668,P35670,O43819 3 |
| Selenium micronutrient network 0.5069946825769516 0.8104000961356869 0.4177102626358171 1.0 1.0 8 Q8WTV0 1 |
| Histone modifications 0.5535669008997485 0.7791304727193961 0.4359028612142483 1.0 1.0 5 Q03164 1 |
| Omega3 omega6 fatty acid synthesis 0.5420368534269279 0.7295404889934821 0.4656711100241182 1.0 1.0 5 Q15067 1 |
| Adipogenesis 0.5093429395232555 0.7261157807847445 0.467767795586204 1.0 1.0 13 Q9NZ45,O75844,P43490,P02545 4 |
| Nephrotic syndrome 0.5047271442681569 0.7232584597059365 0.4695211088207693 1.0 1.0 12 P02545,Q9BT22,Q14108,O75844 4 |
| Tca cycle nutrient use and invasiveness of ovarian cancer 0.70141987829614 0.7200392709195966 0.4715008166961443 1.0 1.0 3 P28482,P27361 2 |
| Il10 antiinflammatory signaling pathway 0.5706443610472303 0.7020968054302862 0.4826187944458251 1.0 1.0 4 P09601 1 |
| Factors and pathways affecting insulinlike growth factor igf1akt signaling 0.5665584415584386 0.6857258681190078 0.4928859912153494 1.0 1.0 4 P05556,P42345,P49841 3 |
| Inhibition of exosome biogenesis and secretion by manumycin a in crpc cells 0.4733131664954073 0.6520131440701101 0.514392693138737 1.0 1.0 8 Q8WUM4,P28482,P31943,P27361 4 |
| Vitamin d receptor pathway 0.4808679243024077 0.649660705898852 0.5159114110097167 1.0 1.0 10 P24941,Q96KA5 2 |
| Osteoblast differentiation and related diseases 0.4835760503007392 0.6294902696469005 0.5290281369867345 1.0 1.0 6 P42224,P27361 2 |
| Nongenomic actions of 125 dihydroxyvitamin d3 0.549458695041072 0.6181124768950855 0.5365011982813623 1.0 1.0 4 P42224,P27361 2 |
| Mitochondrial complex i assembly model oxphos system 0.5052855879130396 0.6171628366207997 0.5371273256037594 1.0 1.0 18 Q9Y6M9,P56556,O95168,O43676,O96000,O95169 6 |
| Folate metabolism 0.4600994529923921 0.5908844749980222 0.5545978288886091 1.0 1.0 8 Q8WTV0 1 |
| 15q112 copy number variation syndrome 0.6649087221095261 0.5894708248657354 0.5555454778582507 1.0 1.0 3 Q7L576,Q9BSJ2 2 |
| Resistin as a regulator of inflammation 0.7725060827250599 0.5864421507239798 0.5575784258011858 1.0 1.0 2 P27361 1 |
| Neovascularisation processes 0.7725060827250599 0.5864421507239798 0.5575784258011858 1.0 1.0 2 P27361 1 |
| Relationship between inflammation cox2 and egfr 0.7725060827250599 0.5864421507239798 0.5575784258011858 1.0 1.0 2 P27361 1 |
| Mfap5mediated ovarian cancer cell motility and invasiveness 0.7725060827250599 0.5864421507239798 0.5575784258011858 1.0 1.0 2 P27361 1 |
| Mthfr deficiency 0.4569853112196744 0.5765899652157263 0.5642164795961739 1.0 1.0 8 P21964 1 |
| Constitutive androstane receptor pathway 0.5024873880230962 0.5637837091740509 0.572901339995127 1.0 1.0 5 P08183 1 |
| Electron transport chain oxphos system in mitochondria 0.5752516208140473 0.5241763097301685 0.6001559166032155 1.0 1.0 43 Q9Y6M9,P12236,O14949,P22695,P00403,O43676,P24539,P25705,O75964,O96000,P21912,O95169,P13073,Q9UDW1,P12235,P14406 16 |
| Cannabinoid receptor signaling 0.523522677162828 0.5188622756071776 0.6038567864031834 1.0 1.0 4 P27361,P10644 2 |
| Wntbetacatenin signaling pathway in leukemia 0.5206980519480486 0.5083336922904997 0.6112193455438444 1.0 1.0 4 P48729,P49841,P14923 3 |
| Pathogenic escherichia coli infection 0.4903288696021738 0.4992505024930964 0.6176029204699927 1.0 1.0 21 Q9BVA1,Q13885,P68371,P07437,Q9BUF5 5 |
| Arrhythmogenic right ventricular cardiomyopathy 0.4548956675047537 0.4955706108852791 0.6201973921104309 1.0 1.0 12 P02545,P16615,P50402 3 |
| G1 to s cell cycle control 0.4811620035245887 0.4922791385990827 0.6225220255895201 1.0 1.0 19 P24941,Q14566,Q9Y619,P33991 4 |
| Nanomaterial induced apoptosis 0.4816405935157246 0.4801061392900889 0.6311519230147251 1.0 1.0 5 O95831 1 |
| Apoptosis modulation and signaling 0.4427134412854595 0.4763322806783185 0.6338376712613882 1.0 1.0 10 Q9NR28,O95831,Q9Y3E5 3 |
| Cholesterol metabolism with bloch and kandutschrussell pathways 0.4911665907826271 0.470174415153223 0.6382304116534367 1.0 1.0 23 Q9BWD1,Q14534,P14324,Q15800,P48449,Q15392,P37268,Q14739,O76062,Q16850 10 |
| Prostaglandin and leukotriene metabolism in senescence 0.6239350912778818 0.4526766149488841 0.6507816210075579 1.0 1.0 3 P63096,P09960 2 |
| Primary focal segmental glomerulosclerosis fsgs 0.4557825548957402 0.4482518062059288 0.6539714778863059 1.0 1.0 15 Q14108 1 |
| Hostpathogen interaction of human coronaviruses mapk signaling 0.4722613154928017 0.4435351029691941 0.6573787346759437 1.0 1.0 5 P51812,P27361 2 |
| Praderwilli and angelman syndrome 0.4371650205421216 0.429566916604396 0.667510707159026 1.0 1.0 6 Q15154,P11802 2 |
| Nad biosynthetic pathways 0.4950680487311737 0.4157806103775311 0.6775705484152104 1.0 1.0 4 P43490 1 |
| Nad metabolism 0.4950680487311737 0.4157806103775311 0.6775705484152104 1.0 1.0 4 P43490 1 |
| Leptininsulin signaling overlap 0.7003244120032445 0.3734446002054371 0.7088175702832475 1.0 1.0 2 P40763 1 |
| Nonalcoholic fatty liver disease 0.5420619259185349 0.3700075315936178 0.711376878641637 1.0 1.0 44 Q9Y6M9,O14949,P22695,P00403,O43676,O96000,P21912,O95169,Q96GC9,Q9UDW1,P14406 11 |
| Oxidative phosphorylation 0.4733006056010019 0.3630388670771031 0.7165758504133448 1.0 1.0 25 Q9Y6M9,P56556,Q15904,O75787,O95168,P24539,O75964,O96000,O95169,P06576,P25705 11 |
| Serine metabolism 0.4469636808356493 0.348907313152322 0.727158894697397 1.0 1.0 5 P34896,O43175 2 |
| Mrna protein and metabolite inducation pathway by cyclosporin a 0.6893755068937548 0.3448486004439502 0.7302081937382661 1.0 1.0 2 P08195 1 |
| Neural crest differentiation 0.3880536367330452 0.293100160308399 0.769445594240741 1.0 1.0 7 P35222,Q92769,P49841,P56545,P05556,Q13547 6 |
| Type ii diabetes mellitus 0.6682887266828846 0.2929895267656904 0.76953015703023 1.0 1.0 2 P28482 1 |
| Il7 signaling pathway 0.3843036284977206 0.277922878926034 0.7810715606710348 1.0 1.0 7 P42224,P28482,P27361 3 |
| Mevalonate arm of cholesterol biosynthesis pathway 0.3912058494214739 0.2744977863703026 0.7837021045340553 1.0 1.0 9 Q9BWD1 1 |
| Nonhomologous end joining 0.5578093306287949 0.2623489146806423 0.7930524537653592 1.0 1.0 3 P78527,P13010 2 |
| Steroid biosynthesis 0.6520681265206801 0.2561401055306587 0.797842654920466 1.0 1.0 2 P51659 1 |
| Pi3kaktmtor signaling pathway and therapeutic opportunities 0.6354420113544175 0.2212519941707156 0.8248962267586724 1.0 1.0 2 P42345 1 |
| Transcription cofactors ski and skil protein partners 0.4084449857896923 0.2187451939596101 0.8268485417257883 1.0 1.0 5 O14744,Q13547,Q96ST3,P21359 4 |
| Parkinubiquitin proteasomal system pathway 0.4576119251908339 0.2153874055562131 0.8294652884933038 1.0 1.0 31 Q9BVA1,Q13885,P68371,P07437,Q9BUF5,O00231 6 |
| Somatroph axis gh and its relationship to dietary restriction and aging 0.6236820762368177 0.1983893611876812 0.8427404405644641 1.0 1.0 2 P42345 1 |
| Onecarbon metabolism and related pathways 0.3646831111907301 0.1870556140398706 0.8516170286948661 1.0 1.0 8 P35790,P34896,O43865 3 |
| Type i collagen synthesis in the context of osteogenesis imperfecta 0.3743244250437336 0.1802650681320776 0.8569444779908775 1.0 1.0 11 P13674,O75718 2 |
| Regulation of wnt bcatenin signaling by small molecule compounds 0.5204868154158107 0.1761184482639572 0.8602008878394245 1.0 1.0 3 P48729,P49841 2 |
| Regulation of apoptosis by parathyroid hormonerelated protein 0.4086850649350604 0.1571541147781761 0.8751233899608826 1.0 1.0 4 Q9BXK5,P49841,Q16611 3 |
| Notch signaling 0.4074675324675287 0.1542378753418222 0.8774221792818566 1.0 1.0 4 Q92769,Q13547,Q92542 3 |
| Cholesterol biosynthesis pathway 0.3690609648987142 0.1476880768566821 0.8825889417332728 1.0 1.0 12 Q14534,Q15800,P48449,P37268,Q16850 5 |
| Photodynamic therapyinduced nfe2l2 nrf2 survival signaling 0.4954081792134574 0.1279775775730451 0.8981667176147483 1.0 1.0 3 P09601 1 |
| Genes related to primary cilium development based on crispr 0.3439382142834676 0.1267032871674273 0.8991752440262888 1.0 1.0 7 O95684,Q10713 2 |
| Thyroid stimulating hormone tsh signaling pathway 0.3723330883404423 0.1198584414913637 0.904595285959064 1.0 1.0 15 P40763,P27361,P24941,Q14160,P04899,P28482,P11802,P42224 8 |
| Intracellular trafficking proteins involved in cmt neuropathy 0.3644834254039888 0.0964077420132388 0.9231967435302276 1.0 1.0 5 O95140,Q15907 2 |
| Fgfr3 signaling in chondrocyte proliferation and terminal differentiation 0.3390815883518818 0.0820291073780035 0.9346235671063724 1.0 1.0 6 P42224,P27361 2 |
| Integrated cancer pathway 0.3450866768374586 0.0799567149457705 0.9362716821680168 1.0 1.0 11 P42224,P24941,P43246 3 |
| Tryptophan metabolism 0.3586579986578166 0.075051035272296 0.9401741060809377 1.0 1.0 15 P51648,Q15392 2 |
| Osteopontin signaling 0.4486218905831866 0.0597097255050678 0.9523868257247086 1.0 1.0 3 P27361 1 |
| Spinal cord injury 0.3544069769716826 0.0391232449936011 0.9687921283293665 1.0 1.0 17 Q9NQC3,P08670 2 |
| Purinergic signaling 0.4239350912778795 0.0344107396760346 0.9725496195215986 1.0 1.0 3 P04899,P63096 2 |
| Novel intracellular components of rigilike receptor rlr pathway 0.3425324675324638 0.0327065561680747 0.9739085956237404 1.0 1.0 4 O00571,Q14258,Q92841 3 |
| Ebsteinbarr virus lmp1 signaling 0.469586374695861 0.0324021607027541 0.9741513394026158 1.0 1.0 2 P28482 1 |
| Tcell antigen receptor tcr pathway during staphylococcus aureus infection 0.3217699826949581 0.0323832313206116 0.9741664349425196 1.0 1.0 9 O95433,P27361 2 |
| Transcription factors regulate mirnas related to cardiac hypertrophy 0.4643146796431471 0.0303283746698081 0.9758051672629968 1.0 1.0 2 P40763 1 |
| Kisspeptinkisspeptin receptor system in the ovary 0.3406174120413935 0.0301345471843072 0.97595974856564 1.0 1.0 4 P27361 1 |
| Serotonin receptor 2 and elksrfgata4 signaling 0.3406174120413935 0.0301345471843072 0.97595974856564 1.0 1.0 4 P27361 1 |
| Serotonin receptor 467 and nr3c signaling 0.3406174120413935 0.0301345471843072 0.97595974856564 1.0 1.0 4 P27361 1 |
| Nanoparticle triggered autophagic cell death 0.4184179917448554 0.0296791400497815 0.976322948421216 1.0 1.0 3 Q96GC9 1 |
| Mammary gland development pathway involution stage 4 of 4 0.4590429845904301 0.0284157815613656 0.977330537418108 1.0 1.0 2 P40763 1 |
| T cell receptor and costimulatory signaling 0.4085192697768607 0.021974805279804 0.9824680531582914 1.0 1.0 3 P48729,P49841 2 |
| Mfap5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement 0.3267766066068578 0.0177705404625715 0.9858219063533996 1.0 1.0 5 P28482,P27361 2 |
| Ddx1 as a regulatory component of the drosha microprocessor 0.3214285714285676 0.0073779970167038 0.9941132634980308 1.0 1.0 4 O60934,P49959,Q92499 3 |
| Nad metabolism sirtuins and aging 0.3195933756176091 0.0054794634466367 0.9956280425921094 1.0 1.0 4 P43490 1 |
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