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Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
Arrhythmogenic right ventricular cardiomyopathy 0.815401125242214 2.430543809643989 0.015076183309066 0.999863872250374 0.7549007043809937 12 P35222,P50402,P15924,P14923,P02545 5
Nonalcoholic fatty liver disease 0.5557012632173217 2.401687515451409 0.0163196425021601 0.999935070269418 0.7549007043809937 44 P00403,P14406,O96000,O14949,O43676,Q9P0J0,Q16611,O95169,O95168,Q86Y39,P10606,P31930,Q9UDW1,P21912,Q9Y6M9 15
Mitochondrial complex iv assembly 0.820362959647233 2.3590162834535273 0.0183234517233279 0.9999803441508835 0.7549007043809937 10 P00403,P14406,P10606,Q7KZN9,Q9Y2R0 5
Influence of laminopathies on wnt signaling 0.8345096496053187 2.3046373701148504 0.0211868912037516 0.9999964512995854 0.7549007043809937 7 P35222,O60725,P50402,O75844,P02545 5
Sphingolipid metabolism integrated pathway 0.8268821414509612 2.2706296990794983 0.0231694040290919 0.999998918359768 0.7549007043809937 7 Q13510,Q06136,Q96G23 3
Sphingolipid metabolism overview 0.8268821414509612 2.2706296990794983 0.0231694040290919 0.999998918359768 0.7549007043809937 7 Q13510,Q06136,Q96G23 3
Mitochondrial complex iii assembly 0.823257431989811 2.254422071434366 0.0241696280674053 0.9999994065857156 0.7549007043809937 7 P31930,O14949,Q6DKK2 3
Sphingolipid metabolism in senescence 0.7854572179177641 2.154497833466824 0.0312011516922976 0.9999999914316398 0.7549007043809937 9 Q13510,Q06136,Q96G23 3
Cholesterol biosynthesis with skeletal dysplasias 0.8417144710822757 2.1268284690420267 0.0334343379454293 0.999999997783956 0.7549007043809937 5 Q15392,Q9UBM7,Q14739 3
7oxoc and 7betahc pathways 0.7887302777836549 2.0985318657082224 0.0358581880213579 0.9999999994911644 0.7549007043809937 7 P61916,Q9UBM7 2
Sphingolipid pathway 0.7718120003785407 2.090322048885615 0.036588879932847 0.9999999996736904 0.7549007043809937 9 O95470,Q06136,Q96G23,Q13510 4
Kennedy pathway from sphingolipids 0.8657767890248326 2.0624418759275907 0.0391656859397568 0.999999999932076 0.7549007043809937 4 Q9UG56,O95470,P48651 3
Glycerophospholipid biosynthetic pathway 0.7830952448122237 2.0419800889808073 0.0411535064326873 0.999999999979818 0.7549007043809937 6 O15228,O95674,P48651 3
Vitamin d metabolism 0.9351371386212044 2.0173282400041614 0.0436612704503089 0.99999999999565 0.7549007043809937 3 P38435,Q9UBM7 2
Overlap between signal transduction pathways contributing to lmna laminopathies 0.726846287008027 1.9943562084543895 0.0461131406139034 0.9999999999990336 0.7549007043809937 12 P35222,O60725,P50402,O75844,P02545,P42167 6
Cholesterol metabolism with bloch and kandutschrussell pathways 0.6233213987628801 1.9511020110820911 0.0510449120440741 0.9999999999999536 0.7549007043809937 21 Q15392,Q9UBM7,Q14534,P37268,Q9BWD1,O00767,P48449,Q14739,Q16850,Q15800 10
Oxidation by cytochrome p450 0.7945080599772866 1.924186873423859 0.054331163888984 0.999999999999994 0.7549007043809937 5 O43169,Q16850,Q6UW02 3
Electron transport chain oxphos system in mitochondria 0.4999597646412818 1.8931849294336325 0.0583332808543728 0.9999999999999994 0.7549007043809937 47 P00403,P14406,O96000,O14949,O43676,O95169,O95168,P10606,Q16718,P31930,Q9UDW1,P13073,Q7KZN9,O75964,P56385,P21912,Q9Y6M9 17
Histone modifications 0.725560053139812 1.86948037968823 0.0615560108425863 1.0 0.7549007043809937 9 Q03164,Q9H7B4 2
Nephrotic syndrome 0.7245613497150241 1.8646566013442971 0.0622295535952435 1.0 0.7549007043809937 9 Q14108,O75844,P02545 3
Statin inhibition of cholesterol production 0.8802816901408511 1.8009681591538675 0.0717078987399801 1.0 0.7549007043809937 3 Q8WTV0,P37268 2
Wntbetacatenin signaling pathway in leukemia 0.7948703831189884 1.76947913648905 0.0768139494940591 1.0 0.7549007043809937 4 P14923,P35222 2
Metabolism of spingolipids in er and golgi apparatus 0.7920259580938407 1.7575656213899884 0.078821447178186 1.0 0.7549007043809937 4 O95470,Q06136 2
Omega3 omega6 fatty acid synthesis 0.7179039542642167 1.7436562890123282 0.0812190416740252 1.0 0.7549007043809937 6 O15254,Q15067 2
Pregnane x receptor pathway 0.7475209063457896 1.7184385192397753 0.0857166595032719 1.0 0.7549007043809937 5 P08183 1
Familial partial lipodystrophy fpld 0.6925968386005905 1.6255537170178038 0.1040446277967923 1.0 0.77595439417758 6 O60725,O75844 2
Ketogenesis and ketolysis 0.7218771985619568 1.604605505723053 0.1085806490146101 1.0 0.77595439417758 5 P23786,P11166,O43772 3
Neural crest differentiation 0.6855296090095497 1.592365265654614 0.111302656030549 1.0 0.7810278495407651 6 P35222 1
Glycerolipids and glycerophospholipids 0.7467556544308325 1.5664971170017377 0.1172322829878669 1.0 0.7896335382860922 4 Q9UG56,O14735,P48651 3
Proximal tubule transport 0.6383542480404734 1.5381568844682507 0.1240102601371118 1.0 0.8103708861332922 12 P08183,P05023,O15439,Q9Y5K8,P11166 5
Endothelin pathways 0.6632921981151962 1.5103993415455974 0.1309415565516622 1.0 0.8340407841225446 7 P42892,P16615 2
Ccl18 signaling pathway 0.6485261847469435 1.491152252680293 0.1359215262279924 1.0 0.8382069891524141 9 P00403,P11166,Q86UE4 3
H19 action rbe2f1 signaling and cdkbetacatenin activity 0.6953484769105697 1.4858561061276645 0.1373171859362316 1.0 0.8382069891524141 5 P35222,Q15648 2
Intracellular trafficking proteins involved in cmt neuropathy 0.6478022197068865 1.4602412720342692 0.1442237760741145 1.0 0.8536882098932436 8 Q9NR77,P20338,Q15907,Q8TB36 4
Progeriaassociated lipodystrophy 0.6393812500697194 1.4454924231510586 0.1483196197208693 1.0 0.8691529715642945 9 O60725,O75844 2
Vitamin a and carotenoid metabolism 0.6835617350910098 1.432819993392286 0.1519092860993272 1.0 0.8777701024493337 5 Q6NUM9 1
Adipogenesis 0.6055037310816128 1.40062091732452 0.1613274625172769 1.0 0.8854925648405034 13 P35222,O75844,P43490,P02545 4
Degradation pathway of sphingolipids including diseases 0.6426698094649885 1.3894073470133603 0.1647089174467009 1.0 0.8854925648405034 6 P17900,O43681,P16278 3
Tyrobp causal network in microglia 0.6414726700718123 1.3837023644285835 0.1664496092897365 1.0 0.8854925648405034 6 P61916 1
Cholesterol biosynthesis pathway 0.6109599905072162 1.3601142503005064 0.1737937722432558 1.0 0.8854925648405034 11 Q9UBM7,P37268,Q14534,P48449,Q16850 5
Epithelial to mesenchymal transition in colorectal cancer 0.5496477577194891 1.357980786429534 0.1744697809107731 1.0 0.8854925648405034 19 P14923,P35222,P15924 3
Mitochondrial immune response to sarscov2 0.6282682315638022 1.34108949118626 0.1798913988280928 1.0 0.8854925648405034 7 Q99623,Q9Y276,O94826,Q9Y6M9 4
Acquired partial lipodystrophy barraquersimons syndrome 0.6938620796604514 1.3404909719302132 0.1800857774925108 1.0 0.8854925648405034 4 O60725 1
Endometrial cancer 0.6085744755502902 1.3177458293683548 0.187588747309424 1.0 0.8854925648405034 10 Q16611 1
Joubert syndrome 0.5896209426143052 1.3144635662616695 0.1886902511172699 1.0 0.8854925648405034 13 Q10713,Q9UM54,Q13432,P36404 4
Mitochondrial complex i assembly model oxphos system 0.4983150347421255 1.2770759685241777 0.2015754281500916 1.0 0.8854925648405034 23 O96000,O43676,Q9P0J0,O95169,O95168,Q9NPL8,Q9Y6M9 7
Photodynamic therapyinduced nfe2l2 nrf2 survival signaling 0.6451224452347515 1.2590006499723772 0.2080300971040669 1.0 0.8854925648405034 5 P07099 1
Copper homeostasis 0.7430960530274353 1.24785862160921 0.2120828362005613 1.0 0.8854925648405034 3 O75880 1
Ppar signaling pathway 0.557525865118964 1.2123507015691235 0.2253781633863594 1.0 0.8854925648405034 15 O15254,Q15067,O00767,Q01469,P23786 5
Lung fibrosis 0.6024490684539509 1.1970095545339747 0.2313028306901179 1.0 0.8854925648405034 6 P15924,Q8IZ81 2
Pilocytic astrocytoma 0.7300751013527428 1.195091357532829 0.2320513382685216 1.0 0.8854925648405034 3 P62993 1
P53 transcriptional gene network 0.5894236161482165 1.1941639973847276 0.2324138232409915 1.0 0.8854925648405034 9 Q9H2H9 1
Glycosylation and related congenital defects 0.5941347780841182 1.174861338444278 0.2400501953057316 1.0 0.889715050952711 7 O75340,Q9BV10,Q2TAA5,Q9H0U3 4
Gastric cancer network 2 0.5460583329989526 1.1470089752271198 0.2513779115327992 1.0 0.902907645474028 15 P35222,Q14739 2
Wnt signaling pathway 0.5822352138946997 1.1360116440137973 0.2559516911250581 1.0 0.902907645474028 8 P35222,Q9BTU6 2
Drug induction of bile acid pathway 0.908484623934792 1.123617508495699 0.2611753252242539 1.0 0.9093421457300324 2 P08183 1
Angiopoietinlike protein 8 regulatory pathway 0.4831924341365347 1.105846789051675 0.2687928393464576 1.0 0.9093421457300324 22 P41440,Q14254,P54619,P18031,Q01518,O00767,Q99570,P49327,P11166,P51812,O75955,O14654,P31749,Q15418 14
Mthfr deficiency 0.5813112947397916 1.095577656226388 0.2732636442536806 1.0 0.9093421457300324 6 P21964 1
Photodynamic therapyinduced hif1 survival signaling 0.553367579402092 1.0583440426693072 0.2898986205728251 1.0 0.9093421457300324 11 Q16611,P11166 2
Regulation of apoptosis by parathyroid hormonerelated protein 0.6267557621552088 1.052362904833337 0.2926330810849915 1.0 0.9093421457300324 4 Q16611,Q07820 2
Metabolic pathway of ldl hdl and tg including diseases 0.8810670618747691 1.023777822391013 0.3059402277894665 1.0 0.9093421457300324 2 P07355 1
Eicosanoid synthesis 0.8721748795850337 0.991670158638728 0.3213584526099686 1.0 0.9093421457300324 2 P09960 1
Irinotecan pathway 0.8714338643942237 0.9890014921307128 0.3226624116220791 1.0 0.9093421457300324 2 O15118 1
15q112 copy number variation syndrome 0.6782802075611545 0.9865714798007836 0.3238527574800394 1.0 0.9093421457300324 3 Q7L576,Q96CW5 2
Amyotrophic lateral sclerosis als 0.5410513385763411 0.9497948322882231 0.3422165122070293 1.0 0.9093421457300324 9 Q9BUN8 1
Regulation of wnt bcatenin signaling by small molecule compounds 0.8603186365320539 0.9491106725114428 0.3425643269057581 1.0 0.9093421457300324 2 P35222 1
Omega9 fatty acid synthesis 0.5478654959056313 0.9354483937788772 0.3495572669447255 1.0 0.9093421457300324 6 O00767 1
Mammary gland development pathway pregnancy and lactation stage 3 of 4 0.6645663454410692 0.9320213539901888 0.3513254898439235 1.0 0.9093421457300324 3 P06753,P61201 2
Hostpathogen interaction of human coronaviruses autophagy 0.6571534469977882 0.9027055102167106 0.3666822112189445 1.0 0.9093421457300324 3 Q99570,Q9NT62 2
Insulin signaling in adipocytes normal condition 0.6571534469977771 0.9027055102166672 0.3666822112189676 1.0 0.9093421457300324 3 P62753,O60343 2
Insulin signaling in adipocytes diabetic condition 0.6571534469977771 0.9027055102166672 0.3666822112189676 1.0 0.9093421457300324 3 P62753,O60343 2
Genes related to primary cilium development based on crispr 0.5347599008308968 0.9007523646835 0.3677199999674605 1.0 0.9093421457300324 8 A0AVF1,Q10713 2
Vitamin b12 metabolism 0.5371915783923886 0.897544557610905 0.3694284082983041 1.0 0.9093421457300324 7 Q8WTV0,Q96EY8 2
Chromosomal and microsatellite instability in colorectal cancer 0.4998892350290274 0.8839298793945165 0.376734066521132 1.0 0.9093421457300324 15 Q16611 1
1q211 copy number variation syndrome 0.5313090630422181 0.8837538270188358 0.3768291164172672 1.0 0.9093421457300324 8 P35222,Q86WJ1,Q9NPH0 3
Complement system in neuronal development and plasticity 0.5298063608809215 0.8763589817985368 0.3808349098109995 1.0 0.9093421457300324 8 Q9NR28,Q16611,Q01518 3
Nuclear receptors in lipid metabolism and toxicity 0.824008892182295 0.8209641953948054 0.4116666630033145 1.0 0.9098731994248132 2 P08183 1
Head and neck squamous cell carcinoma 0.5105994156433598 0.7972840650131965 0.4252860727970411 1.0 0.9199074583542936 9 P35222,P31749,P11802 3
Notch1 regulation of endothelial cell calcification 0.8028899592441712 0.748334295532335 0.4542585431281378 1.0 0.9346474119099082 2 Q9H2H9 1
Insulin signaling 0.349175426193519 0.7478510491660546 0.4545500063760337 1.0 0.9346474119099082 33 P41440,Q14254,Q12846,Q01518,P51812,O75955,P20338,P62993,P11166 9
Proteoglycan biosynthesis 0.7958503149314631 0.724499966095094 0.4687588479778855 1.0 0.9387845453188356 2 Q8TB61 1
S1p receptor signal transduction 0.499965134754999 0.7191285323015445 0.4720617287202433 1.0 0.9387845453188356 7 Q13510,Q9H0H5 2
Metapathway biotransformation phase i and ii 0.4294391314386154 0.69245047271486 0.4886544785545323 1.0 0.9496768539296192 21 P07099,Q86UY6,Q8NEC7,Q6UW02,Q9H2H9,P21964,Q16850 7
Ferroptosis 0.4142249839555561 0.6911338491927496 0.4894814301916335 1.0 0.9496768539296192 23 Q9H2H9,P45880,P37268 3
Glycosaminoglycan degradation 0.4948750477596279 0.6860760931621434 0.4926651255880618 1.0 0.9496768539296192 6 P54802,P16278,P08236 3
Triacylglyceride synthesis 0.5304670328366883 0.6503587294022567 0.5154605292670189 1.0 0.9505358392194636 4 O15228 1
Vitamin d receptor pathway 0.4766760344239413 0.6444792987797051 0.5192646772473344 1.0 0.9505358392194636 10 P08183,Q96KA5,Q92604 3
Ncrnas involved in wnt signaling in hepatocellular carcinoma 0.4786366469421794 0.6287313868638195 0.529524926163865 1.0 0.9505358392194636 8 P35222,Q86UE4 2
Ovarian infertility 0.7617636161541292 0.6122396959321649 0.540379181485428 1.0 0.9505358392194636 2 P11802 1
Male infertility 0.4160393671835375 0.6059866312721203 0.5445236306522374 1.0 0.9518667185591694 21 P41440,P08183,Q15165 3
Sterol regulatory elementbinding proteins srebp signaling 0.3592312506006201 0.6008365080099592 0.5479488853463474 1.0 0.9518667185591694 28 Q8WTV0,Q14534,P37268,O95487,P48449,Q9NR31,Q16850 7
Preimplantation embryo 0.4672443513704903 0.5669603310418136 0.5707411332614611 1.0 0.9650110747404844 7 P05023 1
Aryl hydrocarbon receptor pathway wp2873 0.5068594734890647 0.5574878611842649 0.577194150466489 1.0 0.9688501425428984 4 P07900,Q15185,Q16543 3
Ectoderm differentiation 0.4237241293229643 0.5414447075867139 0.5882010989478128 1.0 0.9728772930971 18 P14923,P35222 2
Melanoma 0.4466954472352824 0.5262439535037241 0.5987187186350784 1.0 0.9744303440097424 12 P21359,P62993,Q16611,P11802 4
Oxidative phosphorylation 0.3345395418139647 0.4746073463296735 0.6350668690726264 1.0 0.9871331174444538 29 O96000,O95169,O95168,Q86Y39,Q16718,Q15904,O75964,P56385,Q9Y6M9 9
Corticotropinreleasing hormone signaling pathway 0.4245769813570664 0.4681444933623724 0.6396812629457902 1.0 0.9895043571927788 15 P14923,P35222 2
Envelope proteins and their potential roles in edmd physiopathology 0.4176947026058911 0.453531785351675 0.6501658607683933 1.0 1.0 16 Q9BTV4,Q15149,P50402,Q14739,P42167,P62993 6
Mitochondrial long chain fatty acid betaoxidation 0.4243239557298044 0.4473370045222666 0.6546317526172121 1.0 1.0 14 Q9BY49,O43772 2
Autosomal recessive osteopetrosis pathways 0.6976658021489426 0.419425757383166 0.6749050030511803 1.0 1.0 2 P51149 1
Liver x receptor pathway 0.6972952945535469 0.4183962312415956 0.6756574415912799 1.0 1.0 2 O00767 1
Hedgehog signaling pathway wp4249 0.4677013549327999 0.4123487105036377 0.6800838505401958 1.0 1.0 4 P48729 1
Ciliopathies 0.4084765251807953 0.4044655875658175 0.6858703783686746 1.0 1.0 16 Q10713,Q7Z4L5,Q93008,O43924,Q9UBB4,Q13432 6
Dna damage response only atm dependent 0.4119342933516557 0.4024213318520578 0.6873739734449482 1.0 1.0 15 Q16611 1
Primary focal segmental glomerulosclerosis fsgs 0.4037401614747368 0.3796467631639815 0.7042076431893038 1.0 1.0 16 P35222,Q14108 2
Nanomaterial induced apoptosis 0.4247297273898548 0.378517142398136 0.7050464616341057 1.0 1.0 6 O95831,Q16611 2
Allograft rejection 0.4211052714853513 0.3741705034817894 0.7082774675526327 1.0 1.0 9 Q9BY49,P08183 2
Autophagy 0.4312749898955554 0.3400062270320689 0.7338518385149444 1.0 1.0 5 P54619,Q99570,Q9NT62 3
Urea cycle and related diseases 0.6591330122267522 0.318596990018631 0.7500321362141895 1.0 1.0 2 Q9UJS0 1
Somatroph axis gh and its relationship to dietary restriction and aging 0.6569099666543186 0.3131875780348534 0.7541381553480646 1.0 1.0 2 P31749 1
Sarscov2 b117 variant antagonises innate immune activation 0.655057428677289 0.3087156268614599 0.7575378555866987 1.0 1.0 2 O94826 1
Wnt signaling 0.4063485989058849 0.3059605319553803 0.7596346965398704 1.0 1.0 7 P35222 1
Relationship between inflammation cox2 and egfr 0.4340185064751429 0.2994156284889198 0.7646229390191064 1.0 1.0 4 Q9H7Z7 1
Alzheimers disease 0.3580918942972487 0.2947356143385979 0.768195854723486 1.0 1.0 74 P28070,Q9Y277,P28072,P35222,O95197,P60900,P49721,P16615,Q9NQC3,P45880,P21796 11
Breast cancer pathway 0.3748269577498571 0.2930958330813919 0.7694489017067907 1.0 1.0 19 Q16611 1
Nonhomologous end joining 0.4741577854715083 0.2701831000128422 0.7870193936101373 1.0 1.0 3 P78527 1
Pparalpha pathway 0.3963810090001087 0.2672893496651236 0.7892463862947081 1.0 1.0 7 P23786,P06493,P11802 3
Alzheimers disease and mirna effects 0.3552263297457795 0.2604862963754597 0.7944886844753192 1.0 1.0 75 P28070,Q9Y277,P28072,P35222,O95197,P60900,P49721,P16615,Q9NQC3,P45880,P21796 11
Burn wound healing 0.388174076757485 0.2378788988485163 0.8119750220787512 1.0 1.0 9 P31949,P08670,P31749,O60885 4
Mirna biogenesis 0.6146721007780691 0.2197193261084963 0.8260897523863602 1.0 1.0 2 Q9HAV4 1
Spinal cord injury 0.3725495916583669 0.2114867514424543 0.8325074692413712 1.0 1.0 15 Q08722,P11802,P06493,Q9NQC3,P08670 5
Mrna protein and metabolite inducation pathway by cyclosporin a 0.6080029640607667 0.2066507284265091 0.8362826397084069 1.0 1.0 2 Q15758 1
Nad metabolism in oncogeneinduced senescence and mitochondrial dysfunctionassociated senescence 0.3606460246942073 0.140393387140122 0.8883491824059784 1.0 1.0 12 P43490 1
Tgfbeta signaling in thyroid cells for epithelialmesenchymal transition 0.3672472285507312 0.1364091663112572 0.8914978277443426 1.0 1.0 5 P08670 1
Gaba receptor signaling 0.348423005565859 0.1085148903598193 0.913587269463126 1.0 1.0 6 P53680,Q96CW1,O95782,O94973,P63010 5
Circadian rhythm genes 0.2816496185520732 0.1018368644875855 0.9188861641168736 1.0 1.0 38 Q03164,P43490 2
3q29 copy number variation syndrome 0.3474387527839599 0.100769775735788 0.9197332201486844 1.0 1.0 7 Q8NCM8,Q09161,O75592,P02786,Q13177,P31749 6
Purinergic signaling 0.3880652335063094 0.0916477581053446 0.9269779056077248 1.0 1.0 3 P08754,P09471 2
Orexin receptor pathway 0.3375576211781272 0.0913065118843781 0.927249043869486 1.0 1.0 18 Q9H4L5,O60313 2
Iron metabolism in placenta 0.5061133753241982 0.0662969881108998 0.9471413810906116 1.0 1.0 2 P02786 1
Hostpathogen interaction of human coronaviruses apoptosis 0.334016274131366 0.0574937059476625 0.9541519197433006 1.0 1.0 4 Q07820 1
Proteasome degradation 0.278090392047327 0.0534693206554636 0.9573579742394752 1.0 1.0 40 P28070,P28072,P49721,Q9UNM6,P60900 5
Metastatic brain tumor 0.4623934790663309 0.0368784569339825 0.9705819169369964 1.0 1.0 2 P04637 1
Erk pathway in huntingtons disease 0.4279362726935896 0.0232209629253339 0.9814740171186964 1.0 1.0 2 P42858 1
Neovascularisation processes 0.2965159377316496 0.0097805174457462 0.9921964005470388 1.0 1.0 3 P28482,P31749 2
Glial cell differentiation 0.2967765839199657 0.0092579227968577 0.9926133518526364 1.0 1.0 2 P09543 1
Follicle stimulating hormone fsh signaling pathway 0.3099109098865706 0.004669013019348 0.9962746801328112 1.0 1.0 7 P62753,P31749 2