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Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
Transport of small molecules 0.5006563048416983 3.5864196336723517 0.0003352493204897 0.368741091447466 0.076660344618664 137 P12235,Q70HW3,Q8IYU8,Q01650,P60900,P61289,P21796,P36404,O15118,Q9HD20,Q8NEW0,P45880,Q9BUN8,P20020,Q9Y487,P30519,P28074,Q93050,P28072,P30825,Q9BPX6,Q9UBX3,P53985,Q13555,P16615,Q4KMQ2,Q8TB61,P40855,Q99436,P49721,Q9GZP9,P09601,Q96PU5,P35611,Q9Y277 35
Gap junction assembly 0.9740121039515844 2.878324060528089 0.00399794218224 0.9958975490685864 0.1870697887820304 3 Q9BVA1,P68371 2
Transport of connexons to the plasma membrane 0.9740121039515844 2.878324060528089 0.00399794218224 0.9958975490685864 0.1870697887820304 3 Q9BVA1,P68371 2
Release of apoptotic factors from the mitochondria 0.9320284697508944 2.7109130352639528 0.0067098221938892 0.9999026209827828 0.1870697887820304 2 O60443 1
Creb phosphorylation 0.9227758007117488 2.673124551158895 0.007514834341864 0.9999679844295992 0.1870697887820304 2 Q15418 1
Activation of ampk downstream of nmdars 0.91626293790029 2.639105315686044 0.0083125152968723 0.999989376441092 0.1870697887820304 5 Q9BVA1,P68371 2
Downregulation of erbb2 erbb3 signaling 0.9113879003558706 2.626372399061437 0.0086300342617637 0.9999931536468202 0.1870697887820304 2 P40818 1
Deubiquitination 0.489073110756455 2.4996662162183827 0.0124310368596818 0.9999999648020296 0.1870697887820304 82 P49721,Q15388,Q96RU2,P28072,Q8TEY7,P28074,P60900,P21796,Q8NB78,Q96K76,Q96FW1,P40818,P45880,Q9NXR7,Q99436,Q9Y277 16
Assembly and cell surface presentation of nmda receptors 0.8814279767090782 2.491283414838517 0.0127282543337015 0.9999999767103064 0.1870697887820304 7 Q13555,Q9BVA1,Q9BUF5,O14936,P68371 5
Ras activation upon ca2 influx through nmda receptor 0.8790048652240059 2.4882874718615913 0.0128359930633354 0.9999999799489904 0.1870697887820304 3 Q13555 1
Long term potentiation 0.8790048652240059 2.4882874718615913 0.0128359930633354 0.9999999799489904 0.1870697887820304 3 Q13555 1
Unblocking of nmda receptors glutamate binding and activation 0.8790048652240059 2.4882874718615913 0.0128359930633354 0.9999999799489904 0.1870697887820304 3 Q13555 1
Synthesis secretion and inactivation of glucose dependent insulinotropic polypeptide gip 0.8781243273048128 2.484584254378203 0.0129702811333558 0.9999999833630208 0.1870697887820304 3 P67812 1
Synthesis secretion and deacylation of ghrelin 0.8781243273048128 2.484584254378203 0.0129702811333558 0.9999999833630208 0.1870697887820304 3 P67812 1
Alpha oxidation of phytanate 0.8784390888334968 2.482734746694347 0.013037813155839 0.9999999848537466 0.1870697887820304 4 P51648 1
Pre notch processing in golgi 0.8747330960854147 2.474046557508525 0.0133592286069026 0.999999990312145 0.1889573365842312 2 P16615 1
Synthesis secretion and inactivation of glucagon like peptide 1 glp 1 0.871199029610491 2.4520856517261187 0.014203084959649 0.9999999970050616 0.1895022369278749 4 P67812 1
Incretin synthesis secretion and inactivation 0.871199029610491 2.4520856517261187 0.014203084959649 0.9999999970050616 0.1895022369278749 4 P67812 1
Synthesis of pe 0.8690391459074739 2.4501298298645517 0.0142804713276201 0.9999999973108756 0.1895022369278749 2 Q9Y6K0 1
Bmal1 clock npas2 activates circadian gene expression 0.8669039145907573 2.4411433123314072 0.0146408433778095 0.9999999983717098 0.1895022369278749 2 P43490 1
Sphingolipid de novo biosynthesis 0.8608126207586166 2.4047878789211388 0.0161818554383899 0.9999999998098292 0.2000135645177563 9 Q96G23,O95470,O15269,P51648 4
Myoclonic epilepsy of lafora 0.846619217081858 2.3552874087028632 0.0185083841812219 0.999999999992614 0.2016494082549551 2 P46976 1
Protein localization 0.6217545047307295 2.3446375689144463 0.0190455830167539 0.9999999999965152 0.2016494082549551 65 Q99595,P50402,P12235,O60830,Q9NS69,P21796,Q8N4H5,O43765,O15228,Q15388,P51648,Q13505,O75874,Q13190,O14925,O15254,P40855,Q9UJS0,P46379,Q9BY49,Q15067,O00116,Q8TB36,P09601,Q5JRX3,Q3ZCQ8 26
Carboxyterminal post translational modifications of tubulin 0.8429958937932989 2.3282242326888696 0.0199002000785348 0.999999999998946 0.2016494082549551 5 Q9BVA1,P68371 2
Endosomal vacuolar pathway 0.8397435897435739 2.3176205558744094 0.020469952037379 0.9999999999995254 0.2016494082549551 4 P01889,Q9UIQ6,P10321 3
Proton coupled monocarboxylate transport 0.8348754448398554 2.3051801988074776 0.0211564833708965 0.9999999999998186 0.2016494082549551 2 P53985 1
Transport of bile salts and organic acids metal ions and amine compounds 0.8351726593093673 2.3019354909981184 0.0213388103649792 0.9999999999998596 0.2016494082549551 3 Q8NEW0,P53985 2
The citric acid tca cycle and respiratory electron transport 0.4888189753227682 2.299063657984422 0.0215013247891353 0.9999999999998882 0.2016494082549551 80 O75880,P13073,O43676,O43819,P21796,P03886,P56134,O75964,P00403,P24539,Q9P0J0,P06576,Q13423,P53985,P47985,O96000,Q9UDW1,Q9Y6M9,O14949,O75306,P48735,Q15120 22
Pink1 prkn mediated mitophagy 0.8363039250040998 2.2969640692126267 0.0216208195294849 0.9999999999999054 0.2016494082549551 9 Q9NS69,Q8N4H5,P21796 3
Acyl chain remodelling of pg 0.8284697508896904 2.2777248478286887 0.0227429763359152 0.9999999999999803 0.2041037952871139 2 Q8NF37 1
Transport of inorganic cations anions and amino acids oligopeptides 0.8285025206256671 2.263644454742345 0.0235959913364778 0.999999999999994 0.2075237186772281 10 P30825,Q70HW3 2
Amino acid transport across the plasma membrane 0.825316673593832 2.25147757759044 0.0243553054889902 0.999999999999998 0.2089796744764246 5 P30825 1
Wax and plasmalogen biosynthesis 0.8227668101473466 2.244163984478124 0.02482185237144 0.9999999999999988 0.2089796744764246 4 O00116 1
Formation of fibrin clot clotting cascade 0.8167259786476946 2.2271625239981767 0.0259364137633426 0.9999999999999998 0.2089796744764246 2 P42785 1
Intrinsic pathway of fibrin clot formation 0.8167259786476946 2.2271625239981767 0.0259364137633426 0.9999999999999998 0.2089796744764246 2 P42785 1
Tysnd1 cleaves peroxisomal proteins 0.8174029808958286 2.220826409716373 0.0263627210959653 1.0 0.2089796744764246 4 O00116 1
Notch3 activation and transmission of signal to the nucleus 0.8118195664368557 2.200969956688141 0.0277381507735308 1.0 0.2160201320007926 3 P67809 1
Cytochrome p450 arranged by substrate type 0.8068396286752937 2.1792886004171095 0.0293102355370296 1.0 0.2160201320007926 3 Q16850 1
Rho gtpases activate iqgaps 0.8097333243237324 2.178567028716814 0.0293638477699464 1.0 0.2160201320007926 9 Q9BVA1,P68371 2
Platelet calcium homeostasis 0.8055991178700324 2.173879506238528 0.0297141855161813 1.0 0.2160201320007926 3 P16615 1
Reduction of cytosolic ca levels 0.8055991178700324 2.173879506238528 0.0297141855161813 1.0 0.2160201320007926 3 P16615 1
Regulation of ifng signaling 0.8047163303985334 2.16538210141165 0.0303584355937307 1.0 0.2160201320007926 4 P15260 1
Synthesis of pips at the er membrane 0.8021352313167287 2.1639332983563206 0.0304694689325912 1.0 0.2160201320007926 2 Q9NTJ5 1
Mapk3 erk1 activation 0.8032569034729846 2.1636576272397745 0.0304906352645699 1.0 0.2160201320007926 3 Q06124 1
Flt3 signaling 0.8042155771478907 2.163186593591792 0.0305268309743838 1.0 0.2160201320007926 4 Q06124 1
Mitophagy 0.7978523084978081 2.1285853200546434 0.0332885841195425 1.0 0.2222940159140184 12 Q9NS69,Q8N4H5,P21796 3
Organelle biogenesis and maintenance 0.4787782146226064 2.107215342405137 0.0350989176230429 1.0 0.2293129284705473 79 A6NIH7,Q9NX63,O43924,P48643,P36542,P56134,O75964,O95684,O94927,Q13561,Q9BW83,Q9NVH1,P68371,Q7Z4L5,P24539,P06576,P07437,Q9BVA1,Q13505,Q9BUF5,Q6UXV4,O75935,P48735,Q86X55,Q9Y512 25
Gamma carboxylation hypusine formation and arylsulfatase activation 0.7901629332972789 2.0906152919887693 0.0365625638307995 1.0 0.2343085940694646 8 O60725 1
Ras processing 0.7892694729001412 2.088891906045202 0.0367174546100108 1.0 0.2343085940694646 6 O43924,O60725,P49356 3
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane 0.783575335404309 2.0722265177720907 0.0382443215137895 1.0 0.235296901869593 4 P12235,P36404 2
Regulation of ifna signaling 0.780559116662123 2.06399713587392 0.0390179879484637 1.0 0.2389851761843407 3 Q06124 1
Vegfr2 mediated cell proliferation 0.7772072905473613 2.0491880170198 0.0404437333638301 1.0 0.2454877537054899 3 O43865 1
Synthesis of pa 0.7784274229400501 2.0376104295061466 0.0415889081851807 1.0 0.2466317919295756 8 Q9NPH0,Q8NF37,Q8N2A8 3
Gap junction trafficking and regulation 0.7784106881428898 2.0370663346816116 0.041643394980583 1.0 0.2466317919295756 10 Q9BVA1,P68371 2
Tp53 regulates transcription of cell death genes 0.7755527822506081 2.0366283517482047 0.041687299403619 1.0 0.2466317919295756 4 Q92696 1
Rsk activation 0.7727214751375807 2.02933191311133 0.0424244949155825 1.0 0.2480910274194532 3 Q15418 1
Creb1 phosphorylation through nmda receptor mediated activation of ras signaling 0.7722801866478215 2.0128354493029255 0.0441319432339881 1.0 0.2490026743751812 6 Q13555,P51812,Q15418 3
Post chaperonin tubulin folding pathway 0.7722924033059216 2.0097834122499876 0.0444541171620693 1.0 0.2490026743751812 8 Q9BVA1,P68371 2
Cytokine signaling in immune system 0.3753122746587403 2.006779379534418 0.0447731594342928 1.0 0.2490026743751812 165 P04083,P60900,P08670,P01889,P52597,P10321,P30154,P28074,O14979,Q8NFH4,P28072,Q13555,Q06124,P15260,Q9Y3Z3,Q15418,Q8N1F7,P51812,Q99436,P51809,P49721,Q9BTX1,Q07820,P09601,Q13126,P55735,Q15369,P31751,Q53EL6 29
Nicotinamide salvaging 0.7675226403431429 2.0062672619001174 0.0448277409407213 1.0 0.2490026743751812 3 P43490 1
Selective autophagy 0.7511491402568873 2.0002339071657076 0.0454750120557339 1.0 0.2505691427327988 27 Q9NS69,Q9BVA1,Q9BUF5,P21796,P68371,Q8N4H5,P08670 7
Mitotic g2 g2 m phases 0.4844856314345734 1.994157964827118 0.0461347942784557 1.0 0.2531877510001654 77 P49721,P07437,O95684,Q9BVA1,P28074,O94927,Q9BUF5,P60900,P68371,O95067,P28072 11
Mitochondrial calcium ion transport 0.7615919006008598 1.9644031003668485 0.0494833635901794 1.0 0.2659360539527495 14 P45880,Q9BPX6,P21796,Q9Y277 4
Mitotic prometaphase 0.4266129078227991 1.9326369502583405 0.0532809372165423 1.0 0.276554409013397 83 P07437,O95684,Q9BVA1,O94927,Q9BUF5,Q7L7X3,P55735,P68371,Q15005,Q8NFH4,O95067,O75935 12
Insertion of tail anchored proteins into the endoplasmic reticulum membrane 0.7540199949585553 1.9247613658483345 0.0542592193682329 1.0 0.2798633420045701 10 P50402,P51648,Q13190,P09601,P46379 5
Signaling by interleukins 0.3957996182470959 1.9127697204108964 0.0557775391303307 1.0 0.2807076667675931 99 P04083,P60900,P61289,P08670,P52597,P30154,P28074,O14979,P28072,Q06124,Q15418,P51812,Q99436,P51809,P49721,Q02750,Q07820,P09601,Q13126,Q53EL6 20
Ctla4 inhibitory signaling 0.7475843177726342 1.9061019504794192 0.0566369797057744 1.0 0.2807076667675931 5 P31751,Q06124 2
Gastrin creb signalling pathway via pkc and mapk 0.746276778542967 1.905589070637469 0.056703541231091 1.0 0.2807076667675931 4 Q15418 1
Constitutive signaling by akt1 e17k in cancer 0.7434163701067784 1.9049563692518243 0.0567857428657923 1.0 0.2807076667675931 2 P31751 1
Cd28 dependent pi3k akt signaling 0.7434163701067784 1.9049563692518243 0.0567857428657923 1.0 0.2807076667675931 2 P31751 1
Aggrephagy 0.7452664175812429 1.8844027106519512 0.0595105234675574 1.0 0.2874945006953833 12 Q9BVA1,Q9BUF5,P68371 3
Formation of tubulin folding intermediates by cct tric 0.7418599088654704 1.868042726121804 0.0617561157141546 1.0 0.2929584641623646 11 Q9BVA1,P68371 2
Ptk6 regulates proteins involved in rna processing 0.7365610537557932 1.867760273742331 0.0617954930578203 1.0 0.2929584641623646 3 Q07666,O75525 2
Class b 2 secretin family receptors 0.7284697508896805 1.837914203016504 0.0660750488868981 1.0 0.3021832235760811 2 Q9Y3E5 1
Intraflagellar transport 0.7347810804909767 1.8352964596876948 0.066461775359534 1.0 0.3029420458248527 10 Q9BVA1,Q9BUF5,P68371,Q7Z4L5 4
Thromboxane signalling through tp receptor 0.7287290850836636 1.832420289882995 0.0668888274303634 1.0 0.3037370847018595 3 Q13685,Q14344 2
Signaling by receptor tyrosine kinases 0.386842518781664 1.8244320822188196 0.0680867754753289 1.0 0.3062788719742665 105 Q06124,Q9UQB8,Q93050,P51812,P31751,P31943,Q15418,Q7L576,O43865,P40818,Q96J02,Q14155,P04792,Q9Y487,P52597 15
Activation of nmda receptors and postsynaptic events 0.723702943908891 1.79889976502698 0.0720345377818592 1.0 0.3179126954764267 19 Q13555,Q9BVA1,Q9BUF5,Q15418,O14936,P68371,Q14155,P51812 8
Heme degradation 0.7236331727465259 1.797169298561181 0.0723087469278507 1.0 0.3179126954764267 5 P30519 1
Nod1 2 signaling pathway 0.7197427248857189 1.7853342544311486 0.0742071158305797 1.0 0.3211740155191021 4 Q15750,Q96J02 2
Ros and rns production in phagocytes 0.7178447499421916 1.7573792967910584 0.0788531797684366 1.0 0.3349827599279261 9 Q9Y487 1
Synthesis of pc 0.7159804403477128 1.7565515192472645 0.0789942826718761 1.0 0.3349827599279261 6 Q9Y6K0,Q8NF37 2
Mapk family signaling cascades 0.4426403159157932 1.7401920071664942 0.0818253086396554 1.0 0.3365880733441354 79 P49721,Q13555,Q02750,Q06124,O60725,P30154,P28074,P60900,P61289,O43924,Q14168,P28072,P04792,Q99436,P30086,P49356 16
G alpha q signalling events 0.712714282632678 1.73822578618464 0.0821710371713184 1.0 0.3365880733441354 7 P04083,Q15418 2
Apoptotic factor mediated response 0.7085097436777954 1.734019369724483 0.0829146464222509 1.0 0.3385681395575249 4 O60443 1
Ub specific processing proteases 0.516053902025914 1.7290141917263415 0.0838065551527578 1.0 0.3386007791531075 69 P49721,Q15388,P28072,Q8TEY7,P60900,P28074,P21796,Q96K76,P40818,P45880,Q9Y277 11
Caspase mediated cleavage of cytoskeletal proteins 0.7072807647038466 1.722163291464944 0.0850399425072729 1.0 0.3421548419940719 5 P08670 1
Post translational modification synthesis of gpi anchored proteins 0.7040270651910934 1.7013457393451417 0.0888780838362715 1.0 0.3514142104419726 6 Q9ULX3 1
Runx1 regulates transcription of genes involved in differentiation of myeloid cells 0.6972718930892445 1.6893075502980248 0.0911605072165349 1.0 0.3524852957988849 3 P17931 1
Mitotic metaphase and anaphase 0.3628808192768809 1.6839155983139318 0.0921979813582731 1.0 0.3524852957988849 135 P50402,P60900,Q7L7X3,Q86XL3,O95067,Q96DE5,P30154,P28074,P68371,Q8NFH4,P42167,P28072,Q9BVA1,P42166,Q9BUF5,Q15005,Q8N1F7,Q99436,P49721,Q9BTX1,P55735 21
Insulin receptor recycling 0.7006428042158257 1.6747418191509815 0.093984898553264 1.0 0.3524852957988849 10 Q9Y487 1
Mitochondrial protein import 0.6792666545692857 1.6668124091870848 0.0955517119692206 1.0 0.3524852957988849 31 Q99595,Q9NS69,O60830,Q15388,Q13505,O14925,P21796,Q5JRX3,Q8N4H5 9
Interferon gamma signaling 0.6983646190051558 1.661526001546365 0.0966078512443961 1.0 0.3524852957988849 13 Q13555,Q06124,P04439,P15260,P18031,P01889,P10321 7
Shc related events triggered by igf1r 0.687544483985765 1.6521911098015425 0.0984955981929587 1.0 0.3541745198495939 2 P08069 1
Dap12 interactions 0.6919975711370332 1.6516237614728866 0.0986112730193475 1.0 0.3541745198495939 5 P01889 1
Transport of vitamins nucleosides and related molecules 0.6937023644599517 1.6497284418013214 0.0989984902692033 1.0 0.3546046493305255 7 P12235,P36404,Q8TB61 3
Class i mhc mediated antigen processing presentation 0.3728533038057317 1.637066024098854 0.1016166747912041 1.0 0.3593274956215536 104 Q6P179,P52888,P60900,P61289,Q9UIQ6,P01889,O00231,P10321,P53992,P55786,P28074,Q9NZ08,P28072,P04439,Q99436,P27824,P49721,Q9UJX4,O95376,Q9UJX6,P55735,Q15369,Q96PU5,Q96J02 24
Recruitment of numa to mitotic centrosomes 0.6778472230542713 1.6175006622710608 0.1057702528383837 1.0 0.3595172156691956 27 P07437,O95684,Q9BVA1,O94927,Q9BUF5,P68371 6
Phase i functionalization of compounds 0.6880321756348325 1.61171885999109 0.1070231316999481 1.0 0.359891511500806 14 O43169,Q16850,P07099,P16435 4
Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects 0.6768683274021527 1.6032605853937008 0.1088771344851977 1.0 0.3634535973569132 2 P11802 1
Ptk6 regulates cell cycle 0.6768683274021527 1.6032605853937008 0.1088771344851977 1.0 0.3634535973569132 2 P11802 1
Activated tak1 mediates p38 mapk activation 0.6743772241992966 1.591817158373985 0.1114257936378089 1.0 0.3692661566934473 2 Q15750 1
Adp signalling through p2y purinoceptor 1 0.6743772241992873 1.5918171583739416 0.1114257936378186 1.0 0.3692661566934473 2 P63218 1
Peroxisomal lipid metabolism 0.6814898279828815 1.5819041149363988 0.1136714614246878 1.0 0.3728201596964312 11 Q9BY49,O15254,P51648 3
Heme signaling 0.6753537223313677 1.5812559691525858 0.1138195227584173 1.0 0.3728201596964312 4 P09601 1
Irs mediated signalling 0.6736642807589515 1.5734236985826116 0.1156207431424563 1.0 0.3759044066148105 4 Q06124 1
Striated muscle contraction 0.6746927781815446 1.5712782489129498 0.1161180312657208 1.0 0.3760189923092032 5 P08670,P09493,P67936 3
Pregnenolone biosynthesis 0.6734064746187063 1.5652870582383858 0.1175156162821728 1.0 0.3784775247397681 5 O95772 1
Interferon alpha beta signaling 0.6677436814147432 1.5180511965561014 0.1290014928232494 1.0 0.3988652085640712 10 P04439,Q06124,Q9Y3Z3,P01889,P10321 5
Attachment of gpi anchor to upar 0.6611203054521458 1.5151368493364803 0.1297377515055859 1.0 0.3988652085640712 4 Q92643,O43292 2
Glycerophospholipid biosynthesis 0.6582002562067204 1.5129364839594468 0.1302957934340116 1.0 0.3988652085640712 27 Q92604,Q8N2A8,Q8NCC3,Q96N66,Q9NPH0,Q8NF37,P35790,Q99829,Q9Y6K0,Q9BZF1,O15228,Q99943 12
Adaptive immune system 0.3440720206297325 1.51035853752622 0.1309519623893797 1.0 0.3988652085640712 169 P52888,P60900,P61289,Q9UIQ6,O43865,P01889,P10321,P53992,P55786,P30154,P28074,P68371,P28072,Q9NZ08,Q9BVA1,Q06124,Q9BUF5,O75935,Q99436,P49721,Q9UJX4,P55735,Q15369,Q96PU5,Q96J02,P31751 26
M phase 0.3430738670148191 1.5052539658970667 0.1322587954765961 1.0 0.3996895757574667 183 P50402,P60900,Q01105,Q7L7X3,Q86XL3,O95067,Q96DE5,O95684,P30154,P28074,O94927,P68371,Q8NFH4,P42167,P28072,P07437,Q9BVA1,P42166,Q9BUF5,Q9Y6X3,Q15005,Q8N1F7,O75935,Q99436,P49721,Q9BTX1,Q9UJX4,P55735 28
Dag and ip3 signaling 0.66048537209241 1.4936694677265805 0.1352620325984546 1.0 0.4053270801175502 7 O43865 1
Peptide ligand binding receptors 0.6588459776537995 1.4904985794620682 0.1360931897028532 1.0 0.4053270801175502 6 Q9BYT8,P04083,Q9NZJ7 3
Class a 1 rhodopsin like receptors 0.6588459776537995 1.4904985794620682 0.1360931897028532 1.0 0.4053270801175502 6 Q9BYT8,P04083,Q9NZJ7 3
Platelet sensitization by ldl 0.6573279201820244 1.4901944201092818 0.1361731231244562 1.0 0.4053270801175502 5 Q06124 1
Antigen presentation folding assembly and peptide loading of class i mhc 0.6625508241905855 1.487218489549867 0.1369571142524748 1.0 0.4053270801175502 14 P53992,P04439,P55735,Q9NZ08,P01889,P27824,P10321 7
Platelet homeostasis 0.6590734437850809 1.479449007370052 0.1390203503684346 1.0 0.4074857325363311 9 P16615,Q06124,P30154 3
Tp53 regulates transcription of death receptors and ligands 0.6492971117116253 1.467834458160189 0.142149194999078 1.0 0.4137228389893145 3 P49327 1
Flt3 signaling in disease 0.6499715033193398 1.4631493094199182 0.1434265277681219 1.0 0.4151502027381082 4 Q06124 1
Kinesins 0.6571478297439488 1.460869615403223 0.1440512265404714 1.0 0.4155538910424847 16 Q9BVA1,P68371 2
Antigen processing ubiquitination proteasome degradation 0.3762660185073315 1.4521275909834803 0.1464661314645703 1.0 0.4169118928825529 84 P49721,Q9UJX4,P55786,P52888,P28074,P60900,Q9UIQ6,Q15369,Q96PU5,Q96J02,P28072,Q99436 12
Regulation of tp53 expression and degradation 0.6516191312299816 1.4438201534328814 0.1487895714444769 1.0 0.4212158108452745 9 P30154,P24941,P06493,P42345,P31751,O96017 6
Cooperation of prefoldin and tric cct in actin and tubulin folding 0.6522648446660023 1.4365789183653042 0.1508376773630764 1.0 0.4222397924108717 16 Q9BVA1,P68371 2
Nrif signals cell death from the nucleus 0.6405693950177906 1.4356299039538032 0.1511076808117624 1.0 0.4222397924108717 2 Q13501 1
Nr1h2 and nr1h3 mediated signaling 0.6388684743362318 1.40356434512232 0.1604486186807219 1.0 0.438630458105068 5 Q8NB78 1
Negative regulation of met activity 0.641695801102771 1.400235180485321 0.1614429041048179 1.0 0.4403571857491258 8 P18031,P40818 2
Aurka activation by tpx2 0.6372736818775172 1.3774081295568534 0.1683861008515266 1.0 0.4498459205537315 23 P07437,O95684,O94927,P68371 4
Slc mediated transmembrane transport 0.6381750823144272 1.3744393633220164 0.1693053228272476 1.0 0.4501684165096585 21 P12235,Q70HW3,Q01650,P36404,Q8NEW0,Q8TB61,P30825,Q9UBX3,P53985 9
Autophagy 0.6015354049503536 1.3511900392822795 0.1766345645117988 1.0 0.4598531736436205 40 Q9NS69,Q9BVA1,Q9BUF5,P21796,P68371,Q8N4H5,P08670 7
Metabolism of lipids 0.3331927067025068 1.3326948115189243 0.1826319766418154 1.0 0.4736693231617594 156 Q9P035,Q9Y217,Q9NZJ7,Q9NPH0,Q06136,Q8N8N7,P23786,Q709F0,Q9BWD1,Q15392,P30536,Q9BZF3,O15269,Q8N2A8,P53992,Q8NF37,Q9H7Z7,Q9NZ01,Q16850,P51648,Q96N66,O95772,Q9NTJ5,O15254,Q99829,P48449,Q9BY49,Q15067,O00116,P53396,O43772,O95470,Q15800,P35790,Q86X55,Q9Y6K0,Q96G23,Q14534,Q99943 39
Iron uptake and transport 0.6306168798660955 1.3294894236434052 0.1836865528312876 1.0 0.4746100762420464 18 P30519,P09601,Q9Y487 3
Sealing of the nuclear envelope ne by escrt iii 0.62823520465078 1.3246369663111996 0.1852915889744033 1.0 0.4764887092324821 11 Q9BVA1,P68371 2
Heparan sulfate heparin hs gag metabolism 0.620781441779976 1.3183344113113404 0.1873917263854805 1.0 0.4787736473014511 5 P08236,Q7LGA3 2
O linked glycosylation of mucins 0.6155699451972139 1.3018568572249156 0.1929653230265287 1.0 0.4864557576648102 4 Q10472,O43505 2
O linked glycosylation 0.6155699451972139 1.3018568572249156 0.1929653230265287 1.0 0.4864557576648102 4 Q10472,O43505 2
Downregulation of erbb2 signaling 0.6188776708154247 1.3017103932155034 0.1930154053476138 1.0 0.4864557576648102 6 P40818 1
Separation of sister chromatids 0.3481632042320377 1.3000333585210753 0.1935895362135469 1.0 0.4864557576648102 100 P28070,P60900,P61289,Q7L7X3,Q9BZD4,P57740,O00231,O43684,Q96DE5,Q9UJX3,P30154,P28074,P68371,Q8NFH4,P28072,O60216,Q9BVA1,Q9HBM1,Q9BUF5,Q15005,P49454,Q99436,P49721,Q9UJX4,Q9BW27,Q9UJX6,P55735,Q12769 28
Signaling by insulin receptor 0.6237355265749966 1.2947274966886235 0.1954142509705527 1.0 0.4901432400943297 15 Q93050,Q06124,Q9Y487 3
Gpcr ligand binding 0.6175577333172011 1.2848185251365096 0.1988557072408392 1.0 0.4942573013304917 8 P04083,Q9NZJ7,P42892,P07602,Q9Y3E5,Q9BYT8 6
P75 ntr receptor mediated signalling 0.6180470919022568 1.272097296177014 0.2033385517510364 1.0 0.5007012290238381 12 Q9NQC3 1
Notch4 activation and transmission of signal to the nucleus 0.6046263345195677 1.268182482735257 0.2047327911679104 1.0 0.5007012290238381 2 Q92542 1
G alpha 12 13 signalling events 0.6079123430944235 1.257541575552653 0.2085575940929511 1.0 0.5062056867944988 5 Q14155,Q14344 2
Signalling to ras 0.5931601782831271 1.2052605657798094 0.2281027278241185 1.0 0.5313360654918348 3 P62993 1
Raf independent mapk1 3 activation 0.5924904426240313 1.1931768371184626 0.2328001241162876 1.0 0.5345229516520658 4 Q06124 1
Negative regulation of nmda receptor mediated neuronal transmission 0.5920312258889604 1.1910128254439658 0.2336485499914111 1.0 0.5345229516520658 4 Q13555 1
Complex i biogenesis 0.6008507003728686 1.1814651494213562 0.2374179901924855 1.0 0.5384090620563474 21 P03886,Q9Y6M9,O43676 3
Caspase activation via extrinsic apoptotic signalling pathway 0.5822935929438969 1.1542515210550184 0.2483970655422198 1.0 0.5508948620614814 3 P49327 1
Immunoregulatory interactions between a lymphoid and a non lymphoid cell 0.5839844339520434 1.1443508953709545 0.2524781439940056 1.0 0.5569132050800252 5 P01889,P10321 2
Recruitment of mitotic centrosome proteins and complexes 0.5911443685514803 1.1424053415350248 0.2532855720036782 1.0 0.5575598353774053 25 P07437,O95684,O94927,P68371 4
Metabolism of steroid hormones 0.5856272225970953 1.1375056352691442 0.2553269701659424 1.0 0.5595984074563466 7 O95772 1
Cristae formation 0.5908016888283201 1.127426674650757 0.2595621262831999 1.0 0.5661673088403026 18 O75964,Q13505,Q9NX63,P24539,Q9NVH1,P06576,P36542,P56134,Q6UXV4,Q9Y512 10
Anchoring of the basal body to the plasma membrane 0.5886751561184502 1.125581207493744 0.2603428262003171 1.0 0.5664142969287933 24 P07437,O95684,O94927,P68371 4
Pyruvate metabolism 0.5861482164885113 1.1158021064617731 0.2645068519432469 1.0 0.5675118578128606 12 Q15120,P21796,P53985 3
Nicotinate metabolism 0.5759704751510565 1.1153353099310437 0.2647067595605961 1.0 0.5675118578128606 4 P43490 1
The role of gtse1 in g2 m progression after g2 checkpoint 0.5458202385420261 1.1143361787552106 0.265134991672534 1.0 0.5675118578128606 46 P49721,Q9BVA1,P60900,P28074,Q9BUF5,P68371,O95067 7
P38mapk events 0.5704626334519523 1.1084620778716816 0.267662307954253 1.0 0.5685582151300577 2 Q16539 1
Formation of atp by chemiosmotic coupling 0.5818586113413629 1.108152482250912 0.2677959684714488 1.0 0.5685582151300577 9 O75964,P24539,P06576,P36542,P56134 5
Signaling by fgfr4 in disease 0.5697508896797154 1.1051359559738154 0.2691006825875686 1.0 0.5685582151300577 2 P62993 1
Transferrin endocytosis and recycling 0.583040433788956 1.1045005701147703 0.2693760563800937 1.0 0.5685582151300577 11 Q9Y487 1
Regulation of signaling by cbl 0.5693950177935945 1.1034729822513365 0.2698218181720386 1.0 0.5685582151300577 2 P62993 1
Erythropoietin activates ras 0.5693950177935945 1.1034729822513365 0.2698218181720386 1.0 0.5685582151300577 2 P62993 1
Processing of smdt1 0.580712166443158 1.1026263268408212 0.2701894724962081 1.0 0.5685582151300577 9 Q9BPX6 1
Signaling by ntrk3 trkc 0.5699537201851153 1.096348382405696 0.2729263437137168 1.0 0.5701731210426315 3 Q8WX92,P62993 2
Signaling by erythropoietin 0.5695977216091095 1.0946787869459411 0.2736573852650446 1.0 0.5706047607654121 3 P19174,P62993 2
Hedgehog off state 0.541549227715844 1.0868548160606444 0.2771009776873163 1.0 0.5751626949878942 46 P49721,Q9BVA1,P60900,P28074,Q9BUF5,P68371,Q7Z4L5,P28072 8
Signaling by gpcr 0.5674539527371145 1.072461941025055 0.2835125995841894 1.0 0.583177341273625 34 P04083,P30154,Q9NZJ7,P31751,Q15418,O43865,Q9BYT8,Q14155,P51812 9
Glycogen storage diseases 0.5641876375447714 1.069315194745213 0.2849276660997821 1.0 0.5845296447514331 3 P46976 1
Cyclin a b1 b2 associated events during g2 m transition 0.5732921692154754 1.0668760299471618 0.2860278201861796 1.0 0.5853987341701474 9 O95067 1
Phospholipid metabolism 0.5560279102353054 1.0625647081770373 0.2879793987226866 1.0 0.5853987341701474 39 Q9Y217,Q9NPH0,Q10713,O15228,Q8N2A8,Q8NCC3,Q8NF37,P42356,P43304,Q9BZF1,Q96N66,Q9NTJ5,Q99829,O96017,Q92604,P35790,Q53H12,Q9Y6K0,Q99943 19
Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins 0.5127903366231082 1.0536620099357263 0.2920376879246982 1.0 0.5888793004872509 53 O75880,P13073,O43676,O43819,P03886,P36542,P56134,P00403,O75964,P24539,Q9P0J0,P06576,P56385,P47985,O96000,P21912,Q9UDW1,P15954,Q9Y6M9,O95168,O14949,O75306,Q9Y375 23
Signaling by type 1 insulin like growth factor 1 receptor igf1r 0.5660696844642892 1.0509837719210773 0.2932660431596221 1.0 0.5888793004872509 6 Q06124 1
Activation of puma and translocation to mitochondria 0.5580071174377146 1.0502977798696107 0.2935812256073467 1.0 0.5888793004872509 2 Q13625 1
Tp53 regulates transcription of genes involved in g1 cell cycle arrest 0.5580071174377146 1.0502977798696107 0.2935812256073467 1.0 0.5888793004872509 2 P24941 1
Tp53 regulates transcription of genes involved in cytochrome c release 0.5580071174377146 1.0502977798696107 0.2935812256073467 1.0 0.5888793004872509 2 Q13625 1
Interleukin 4 and interleukin 13 signaling 0.5703764862406571 1.0385864490057857 0.298997110728803 1.0 0.5922331311489425 12 P08670,P04083,P09601 3
Peptide hormone metabolism 0.5684786894036977 1.0384186316605113 0.2990751990915901 1.0 0.5922331311489425 10 P67812,Q15005 2
Sulfur amino acid metabolism 0.567026420683558 1.0367160546398169 0.2998682075893777 1.0 0.5922331311489425 9 Q9UBX3 1
Ion homeostasis 0.5675432107083607 1.0338943325071135 0.3011855648219494 1.0 0.5922331311489425 10 Q13555,O43865,P16615,P20020 4
Cardiac conduction 0.5675432107083607 1.0338943325071135 0.3011855648219494 1.0 0.5922331311489425 10 Q13555,O43865,P16615,P20020 4
Regulation of plk1 activity at g2 m transition 0.5673683914139657 1.0336572027723128 0.3012964471880188 1.0 0.5922331311489425 29 O95684,P07437,O94927,P68371,O95067 5
Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways 0.5634601440059036 1.0317992752544014 0.3021661588701696 1.0 0.5930929470241384 7 P09601,Q15750,Q96J02 3
Maturation of sars cov 2 nucleoprotein 0.5553577785688817 1.0279664451220225 0.3039656119962584 1.0 0.5957725995126664 3 Q96SB4,Q99873 2
Metabolism of porphyrins 0.5641101083324279 1.0172979631911003 0.3090117052593006 1.0 0.6022216755905689 10 Q7KZN9,P09601,P30519 3
Signaling by erbb2 0.5611747902356439 1.0085820343954897 0.3131751269453779 1.0 0.6077457909039018 9 P40818 1
Signaling by hedgehog 0.5125580584793225 1.0023881067538531 0.3161561839907616 1.0 0.6100791623562939 51 P49721,Q9BVA1,P60900,P28074,Q9BUF5,Q9GZP9,P68371,Q7Z4L5,Q96J02,P28072,Q99436 11
Ion transport by p type atpases 0.5608028545216023 1.001321971148465 0.3166711740995214 1.0 0.6102146781805384 10 Q13555,Q9HD20,P16615,P20020 4
Neurotransmitter receptors and postsynaptic signal transmission 0.5601172061463271 0.9997481393491688 0.3174324090203524 1.0 0.6104380190612898 30 Q13555,Q9BVA1,Q9BUF5,Q15418,O14936,P68371,Q14155,P51812 8
Cholesterol biosynthesis 0.5618226945826392 0.9893024508222704 0.3225151853228001 1.0 0.617142028260644 14 Q16850,Q15800,P48449,Q9BWD1,Q15392,Q14534 6
Translocation of slc2a4 glut4 to the plasma membrane 0.5567890499924588 0.9813668977307118 0.3264118439167633 1.0 0.6208076113685395 30 P68371,Q9BVA1,Q9UIQ6 3
Cilium assembly 0.5159849354206049 0.9807962695990048 0.3266932182274675 1.0 0.6208076113685395 49 O95684,P07437,Q9BVA1,O94927,A6NIH7,Q9BUF5,O43924,P68371,Q7Z4L5,O75935 10
Nuclear envelope ne reassembly 0.5123630549151373 0.9782615476518594 0.3279449827082281 1.0 0.6223243655265408 50 P50402,Q9BVA1,Q9BTX1,P42166,Q9BUF5,P55735,P68371,Q8NFH4,P42167,O95067,Q86XL3 11
Ion channel transport 0.5568569608101938 0.9666938584085352 0.3336970982347347 1.0 0.6246008441719727 27 Q13555,P16615,Q93050,Q9HD20,Q4KMQ2,Q96PU5,Q9Y487 7
Erk mapk targets 0.5507809170770595 0.9587125355841682 0.3377035816208318 1.0 0.6286693541163925 9 P51812,Q15418 2
Mapk targets nuclear events mediated by map kinases 0.5507809170770595 0.9587125355841682 0.3377035816208318 1.0 0.6286693541163925 9 P51812,Q15418 2
Neuronal system 0.5179594884826494 0.9536253437280332 0.3402733223608116 1.0 0.6308851328095049 47 Q13555,Q9BVA1,Q9BUF5,Q15418,O14936,P68371,P21964,O95197,Q14155,P51812 10
Insulin receptor signalling cascade 0.542484362395619 0.9485671929942175 0.3428407832730951 1.0 0.6339320143540248 5 Q06124 1
Adrenaline noradrenaline inhibits insulin secretion 0.5323843416370012 0.93115410688925 0.3517738535452994 1.0 0.6405463669005022 2 P63218 1
Synthesis of bile acids and bile salts via 7alpha hydroxycholesterol 0.5339978640085428 0.9283312214573975 0.3532357835096316 1.0 0.6405463669005022 3 O14734,P51659 2
Stimuli sensing channels 0.5431009995028495 0.928326877627692 0.3532380360702345 1.0 0.6405463669005022 8 Q9C0H2,Q9H4A3,Q96PU5,Q4KMQ2,Q12797 5
Mrna decay by 3 to 5 exoribonuclease 0.5500521383423549 0.9279741263429354 0.3534209910668222 1.0 0.6405463669005022 15 Q96B26,Q9NQT4,Q6PGP7,Q969T7 4
Transmission across chemical synapses 0.5368030324611952 0.9250058773039044 0.3549628502706108 1.0 0.642492124764219 37 Q13555,Q9BVA1,Q9BUF5,Q15418,O14936,P68371,P21964,Q14155,P51812 9
Cd163 mediating an anti inflammatory response 0.5306049822064066 0.9229187597524442 0.3560495435426141 1.0 0.6433687552301881 2 Q16539 1
Protein protein interactions at synapses 0.5462202948667859 0.9164007400539496 0.3594567473229082 1.0 0.6463625915164222 13 O14936,O95197 2
Transcriptional regulation by mecp2 0.5450814072217314 0.9108410593093014 0.3623791249677612 1.0 0.6483975920157053 13 Q13555,Q92769,P18031,P42858,Q13451 5
Transcription of e2f targets under negative control by p107 rbl1 and p130 rbl2 in complex with hdac1 0.5277580071174375 0.9097555868463562 0.3629514217697243 1.0 0.6483975920157053 2 P06493 1
Sema4d induced cell migration and growth cone collapse 0.5309829059829182 0.9043589907966838 0.3658050760121636 1.0 0.650879925674798 4 P35580,Q13464,P60660 3
Epha mediated growth cone collapse 0.5309829059829182 0.9043589907966838 0.3658050760121636 1.0 0.650879925674798 4 P35580,Q13464,P60660 3
Mitochondrial biogenesis 0.5423958967199345 0.9020636193658008 0.3670230733091248 1.0 0.650879925674798 30 O75964,Q13505,Q9NX63,P24539,Q9NVH1,P48735,P06576,P36542,P56134,Q6UXV4,Q9Y512,Q86X55 12
Ethanol oxidation 0.5280792084080633 0.9008618722707948 0.3676617655961869 1.0 0.650879925674798 3 P30837 1
Hs gag degradation 0.5262396510186842 0.8923396968039493 0.3722108829010875 1.0 0.65546615310992 3 P08236 1
Met activates pi3k akt signaling 0.5238434163701092 0.8916849486256467 0.3725618232815733 1.0 0.65546615310992 2 P62993 1
Death receptor signalling 0.5411403976184272 0.8808851735449067 0.3783799730862833 1.0 0.6621649529009959 16 Q9NQC3,P49327,Q92769,Q14155 4
Met receptor recycling 0.5242165242165332 0.872910436307392 0.3827118973881789 1.0 0.6651699663999855 4 P20338,P46109,P62993 3
Mecp2 regulates neuronal receptors and channels 0.5296533801367292 0.871679294478627 0.3833833589687425 1.0 0.6651699663999855 7 Q92769,Q13451 2
Peroxisomal protein import 0.5397850649622296 0.8715400463725961 0.3834593499158263 1.0 0.6651699663999855 17 Q9BY49,Q15067,O00116,O75874,O15254 5
Interaction between l1 and ankyrins 0.5215379138483449 0.8705943807535694 0.3839756657352509 1.0 0.6651699663999855 3 Q13813,Q12955 2
Signaling by flt3 fusion proteins 0.5215379138483379 0.8705943807535369 0.3839756657352686 1.0 0.6651699663999855 3 Q14789,P62993 2
Inlb mediated entry of listeria monocytogenes into host cell 0.5245901639344205 0.8555268923983909 0.3922595231915498 1.0 0.6738799925263717 6 O14964,Q99961,P62993,Q92783,P42566 5
Respiratory electron transport 0.5097918165538053 0.8505887323437049 0.3949978507620648 1.0 0.6765755945637365 44 O75880,P13073,P00403,P47985,O14949,O43676,O75306,O43819,O96000,P03886,Q9UDW1,Q9Y6M9 12
Transcriptional activation of mitochondrial biogenesis 0.5302250195824485 0.8487106742436091 0.3960423051318265 1.0 0.6766750219686998 11 P48735,Q86X55 2
Diseases of signal transduction by growth factor receptors and second messengers 0.3092398594049712 0.8324819779667952 0.40513694656176 1.0 0.6873519736161892 127 P60900,P61289,P62942,P49589,O95684,P30154,P28074,Q6RW13,Q9NRY5,P28072,P30086,Q13555,Q06124,P51114,Q99436,P49721,Q02750,Q9GZP9,P31751 19
Atf4 activates genes in response to endoplasmic reticulum stress 0.5249655412320864 0.8181206972017027 0.4132882716987689 1.0 0.6975534006928591 12 Q96B26,Q9NQT4,Q92945 3
Recycling pathway of l1 0.5301733470512091 0.8180193335120066 0.4133461477866578 1.0 0.6975534006928591 20 P68371,Q9BUF5,Q9BVA1,Q15418 4
Initiation of nuclear envelope ne reformation 0.5282544067758106 0.8117685197150876 0.4169244688274451 1.0 0.7010053569010475 18 O95067,P50402,P42167,Q86XL3 4
Nuclear events kinase and transcription factor activation 0.5229116453553656 0.80826381178734 0.4189387302002187 1.0 0.7035299116703796 12 P51812,Q15418 2
Ksrp khsrp binds and destabilizes mrna 0.5231810786035187 0.8045473854821859 0.4210809144527165 1.0 0.7062628540698376 13 Q96B26,Q9NQT4,Q92945 3
Raf activation 0.5119696871323186 0.7815101624385099 0.4345025020282755 1.0 0.7199727449067561 8 Q13555,P30154 2
Costimulation by the cd28 family 0.515745288966573 0.7796234250517877 0.4356125635254249 1.0 0.7200728158516662 11 P31751,Q06124 2
Regulation of mecp2 expression and activity 0.5114610025965409 0.7721027428799839 0.4400535778194581 1.0 0.7247941281732252 9 Q13555,P42858 2
Synthesis of very long chain fatty acyl coas 0.5062607114536906 0.7624706630801407 0.4457791459919209 1.0 0.7298436614569398 7 Q9NZ01 1
Signaling by egfr 0.5098968519347498 0.7461487509230125 0.4555775626301122 1.0 0.7405834311949216 12 Q14155,O14964,Q06124 3
Vitamin b5 pantothenate metabolism 0.4963980539172427 0.7450274214505359 0.4562551429616639 1.0 0.7408071670336128 4 P49327,Q9NVE7 2
Cell surface interactions at the vascular wall 0.5089381379032519 0.7313189179401394 0.4645843778689773 1.0 0.750723864045 14 P35613,Q01650,Q06124,P53985 4
Cargo concentration in the er 0.5077293306743742 0.730477103108088 0.4650986038179665 1.0 0.750723864045 13 P49755,Q9HCU5,Q15363,P53992,Q96PC5,Q13190,Q12907 7
Runx1 regulates expression of components of tight junctions 0.4825622775800709 0.7039626427882043 0.4814560383690551 1.0 0.7683623800076462 2 Q13951 1
G alpha i signalling events 0.5021295243022965 0.677756125349864 0.4979263338101525 1.0 0.7834345527379922 20 O43865,P04083,P30154,Q9NZJ7 4
Pi3k akt signaling in cancer 0.486697253797937 0.6727587843798356 0.5011007626749753 1.0 0.7852797117871003 7 Q06124 1
Traf6 mediated irf7 activation 0.4754448398576438 0.6723066391306487 0.5013885040273163 1.0 0.7852797117871003 2 Q14258 1
Traf3 dependent irf activation pathway 0.4754448398576438 0.6723066391306487 0.5013885040273163 1.0 0.7852797117871003 2 Q14258 1
Irf3 mediated activation of type 1 ifn 0.4754448398576383 0.6723066391306235 0.5013885040273323 1.0 0.7852797117871003 2 Q9NZI8 1
Met activates ras signaling 0.4793447293447306 0.6681593292372718 0.5040318936237842 1.0 0.7876215923141594 4 Q9NWH9,Q96P70,P62993 3
Perk regulates gene expression 0.4929453022715109 0.6552700629436532 0.5122938919086133 1.0 0.7969016096356206 14 Q96B26,Q9NQT4,Q92945 3
Regulation of innate immune responses to cytosolic dna 0.4757834757834823 0.6522943493967126 0.5142113045746948 1.0 0.798107619775059 4 Q9NZI8,P19474,Q9UJV9 3
G protein mediated events 0.4854539256676577 0.6516805833687084 0.514607250877789 1.0 0.798107619775059 9 O43865 1
Signaling by moderate kinase activity braf mutants 0.4869366276408465 0.6513597022180729 0.5148143174205009 1.0 0.798107619775059 10 Q13555,P30086 2
Response of eif2ak1 hri to heme deficiency 0.4702741189035174 0.6385234258214825 0.5231330098539888 1.0 0.8081006163183786 3 P08243,P20042 2
Circadian clock 0.4789988679051646 0.6299647151874128 0.5287176701395129 1.0 0.8141421362866572 8 P43490,Q86X55 2
Signaling by notch2 0.4640569395017775 0.6222392206541606 0.533784579997179 1.0 0.8201035204435941 2 Q92542 1
Ire1alpha activates chaperones 0.4904659595878838 0.6165322392205067 0.5375433008769634 1.0 0.8233420055949724 22 Q9HCU5,O95070,Q9Y5M8,Q13217,O76024,P43307,P35611 7
Muscle contraction 0.4901586314352786 0.6129531330001438 0.5399073293416643 1.0 0.8258114335080975 24 Q13555,P04083,P16615,P05023,P60660,P14649,O43865,P08670,P20020 9
Signaling by braf and raf1 fusions 0.4878897515735209 0.6056802370384233 0.5447271099335711 1.0 0.8322556735287968 21 Q13555,Q02750,Q6RW13,Q9NRY5,P51114,Q53H12,P30086 7
Unfolded protein response upr 0.4789612445508939 0.5993542836631418 0.5489366559835775 1.0 0.837754273647907 38 Q9HCU5,O95070,Q9Y5M8,Q9NQT4,Q13217,Q9UBS4,Q96B26,O76024,P43307,P35611,Q5RKV6,Q92945 12
Post translational protein modification 0.2806212083325643 0.5954743207343233 0.5515264592628961 1.0 0.8389072085462234 353 O43852,Q9BU89,O60725,P60900,P61289,P21796,Q8NB78,Q92696,O76024,P46977,P45880,Q9BUN8,Q07065,P53992,Q8TEY7,Q10472,P61978,P28074,Q9BT78,Q9ULX3,Q96K76,P68371,Q8NFH4,P40818,P28072,O43292,Q15388,Q9BVA1,P04843,Q13190,Q9BUF5,Q12907,Q8N1F7,O75935,Q9NXR7,Q99436,Q96RU2,P49721,Q9BTX1,Q15363,Q9BT22,Q13217,O15027,Q9GZP9,P55735,Q15369,Q15293,Q9Y3B3,Q96FW1,Q9Y277 50
Cellular response to chemical stress 0.3761410721739701 0.5915149122240708 0.5541754665001333 1.0 0.8399354476508766 71 O75880,P13073,P00403,P49721,Q8TED1,P60900,P28074,O43819,P09601,Q86X55,Q8TCT9,P28072,Q99436,P30519 14
Pkmts methylate histone lysines 0.4737174384090126 0.5911845236349444 0.5543967912112957 1.0 0.8399354476508766 10 Q9H7B4 1
Copi independent golgi to er retrograde traffic 0.4858158815005078 0.590804752339438 0.5546512504166867 1.0 0.8399354476508766 25 Q9BVA1,Q10472,Q9BUF5,Q15042,P68371,O75935 6
G beta gamma signalling through cdc42 0.4565836298932431 0.5898207014631011 0.5553108623370335 1.0 0.8400071699298898 2 P63218 1
Nrage signals death through jnk 0.4631051396968588 0.5860313649685883 0.557854437617292 1.0 0.8403775913171848 5 Q14155,Q9NY61 2
Interleukin 17 signaling 0.4780673069864235 0.5858082156294598 0.5580044021586454 1.0 0.8403775913171848 14 P51812,Q15418,P30154 3
Extra nuclear estrogen signaling 0.4725236937450786 0.5858061052959996 0.5580058204737284 1.0 0.8403775913171848 10 P04792 1
Basigin interactions 0.4652119720646643 0.576611875939141 0.5642016748101697 1.0 0.8469198006997296 7 P53985,Q01650 2
Negative regulation of mapk pathway 0.4660934033218306 0.5722929393152242 0.5671235323633896 1.0 0.850375394975487 8 P30086,P30154 2
Conversion from apc c cdc20 to apc c cdh1 in late anaphase 0.4658859669725418 0.5635418151616735 0.5730659946789891 1.0 0.8583477562222414 9 Q96DE5,Q9UJX6,Q9UJX4 3
Cytoprotection by hmox1 0.4185171646493371 0.559766287947263 0.5756388611516225 1.0 0.8598360957078377 60 O75880,P13073,P00403,P49721,P60900,P28074,O43819,P09601,Q86X55,Q8TCT9,P28072,Q99436,P30519 13
Hcmv early events 0.4691210948915628 0.5593252359916973 0.5759397754777718 1.0 0.8598360957078377 40 Q9BTX1,Q9BVA1,Q9BUF5,P68371,Q8NFH4 5
Dex h box helicases activate type i ifn and inflammatory cytokines production 0.4459074733095959 0.544192268432831 0.5863091716891926 1.0 0.8677628733091394 2 Q08211 1
Signaling by retinoic acid 0.4564575838723531 0.5383306337060524 0.5903488060545183 1.0 0.8709231848460206 7 Q15120 1
Signaling by fgfr2 0.4729393263498012 0.5333952253930674 0.5937600219382551 1.0 0.8730234571094724 21 Q06124,P52597 2
Signaling by fgfr 0.4729393263498012 0.5333952253930674 0.5937600219382551 1.0 0.8730234571094724 21 Q06124,P52597 2
Myd88 independent tlr4 cascade 0.470311858482805 0.5309072172622994 0.5954830761905388 1.0 0.8730234571094724 18 P51812,Q06124,Q15418,P30154 4
Map2k and mapk activation 0.4565196715623228 0.5302755685525311 0.5959208832995253 1.0 0.8730234571094724 8 P30086 1
Ngf stimulated transcription 0.4421502313990786 0.5173037549817185 0.6049441332268457 1.0 0.8810863596467434 3 P50570,Q00535 2
Signaling by vegf 0.4697788220986684 0.5158556469463691 0.6059552335743459 1.0 0.8816230969925796 22 Q9UQB8,P04792,O43865,Q7L576 4
Fgfr2 alternative splicing 0.4645817745872958 0.5134394618784354 0.6076439475768545 1.0 0.8822089905560256 16 P31483,P31943,P52597 3
Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand 0.4690137069738553 0.5080564305173894 0.6114137692099746 1.0 0.884940024214814 29 P68371,Q9BUF5,Q9BVA1 3
Hur elavl1 binds and stabilizes mrna 0.4449706571418798 0.5079904840611515 0.6114600167315187 1.0 0.884940024214814 5 Q01105,P39687 2
Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps 0.4633759376771944 0.5031469053613202 0.6148609909160991 1.0 0.8867498526084212 17 O43852,Q5JRA6,Q13217,Q02818,O76024,O43493,Q15293,Q07065 8
Adp signalling through p2y purinoceptor 12 0.4382342470630144 0.5009113176672546 0.6164335370090526 1.0 0.8867498526084212 3 P04899,P63218 2
Gaba receptor activation 0.4382342470630144 0.5009113176672546 0.6164335370090526 1.0 0.8867498526084212 3 P04899,P63218 2
Gaba b receptor activation 0.4382342470630144 0.5009113176672546 0.6164335370090526 1.0 0.8867498526084212 3 P04899,P63218 2
Josephin domain dubs 0.4334519572953751 0.4921097260498759 0.6226417769774726 1.0 0.891342644926049 2 P54727 1
G alpha z signalling events 0.4383903133903202 0.4908270309400129 0.6235487899110537 1.0 0.891342644926049 4 P04899,P05771,P63218 3
G alpha s signalling events 0.4383903133903168 0.4908270309399981 0.6235487899110641 1.0 0.891342644926049 4 P04899,P63218,Q9Y3E5 3
Activation of ppargc1a pgc 1alpha by phosphorylation 0.4330960854092542 0.4906415624029644 0.623679984787906 1.0 0.891342644926049 2 Q16539 1
Collagen biosynthesis and modifying enzymes 0.4488460443930566 0.4890752258497614 0.6247884400980348 1.0 0.8919976480900144 9 Q32P28,P13674 2
Trna modification in the nucleus and cytosol 0.4491026251127185 0.4824810631509533 0.6294642476134076 1.0 0.8962116873834525 10 O75648,Q08J23 2
Signal amplification 0.4387027797576559 0.4714747728110918 0.6373017306343522 1.0 0.9042171400520488 6 P04899,Q14344,Q13685,Q16539,P63218 5
Negative regulation of the pi3k akt network 0.4444964232364753 0.4627144259402393 0.6435690765511388 1.0 0.9121660878390108 10 P31751,Q06124 2
Egfr downregulation 0.4382917419456331 0.4524062022584562 0.6509763796492072 1.0 0.9182303918623002 8 Q14155 1
Disorders of transmembrane transporters 0.3462314417820992 0.4521040830288824 0.6511940023921414 1.0 0.9182303918623002 74 P49721,Q9BTX1,Q9BUN8,Q8N1F7,P60900,P28074,Q9GZP9,P55735,Q8NFH4,P28072,Q99436,P53985 12
Cell cycle mitotic 0.2780997545314678 0.4509294958359168 0.652040364198889 1.0 0.9184798559351908 233 P50402,P60900,Q7L7X3,Q9Y619,Q86XL3,O95067,Q96DE5,O95684,P30154,P28074,O94927,P68371,Q8NFH4,P42167,P28072,Q14566,P07437,Q9BVA1,P42166,Q9BUF5,Q9Y6X3,Q15005,Q8N1F7,O75935,Q99436,P49721,Q9BTX1,P55735,P31751 29
Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components 0.4431081518514572 0.4423036460548742 0.658269492903417 1.0 0.9224658007744098 12 Q9UJX4,Q9UJX6,Q96DE5,O43684,Q9UJX3 5
Apc cdc20 mediated degradation of nek2a 0.4431081518514572 0.4423036460548742 0.658269492903417 1.0 0.9224658007744098 12 Q9UJX4,Q9UJX6,Q96DE5,O43684,Q9UJX3 5
Diseases of mitotic cell cycle 0.442903351025716 0.4414266624915896 0.6589041434102927 1.0 0.9224658007744098 12 Q96DE5,P11802,Q9UJX6,Q9UJX4 4
Toll like receptor tlr1 tlr2 cascade 0.4465293292052809 0.4381119485551307 0.6613051332445896 1.0 0.9231732455451448 15 P51812,Q15418,P30154 3
Transcriptional regulation of white adipocyte differentiation 0.4305952597733146 0.437942368332791 0.6614280614948085 1.0 0.9231732455451448 6 Q86X55 1
Class i peroxisomal membrane protein import 0.4363757210558338 0.4362190346458184 0.6626778188073552 1.0 0.9238818807953508 9 P51648,P40855 2
Translation of sars cov 1 structural proteins 0.4286706467162501 0.4300801762089002 0.6671373198411135 1.0 0.9273681892826826 6 Q10472 1
Protein folding 0.4506496393368833 0.4221381463573573 0.6729241859113935 1.0 0.92976030520688 33 Q9BVA1,Q9BUF5,P36404,P48643,P68371,P61758,Q9Y2T2,Q15813 8
Disinhibition of snare formation 0.4175863296546875 0.4168753860093925 0.6767695581258271 1.0 0.9325933004286316 3 P05771,O00186 2
Heme biosynthesis 0.4222777341839973 0.4144224769601818 0.6785647306122977 1.0 0.9325933004286316 5 Q7KZN9 1
Pyruvate metabolism and citric acid tca cycle 0.4500650143247872 0.4137704583944986 0.6790422208556315 1.0 0.9325933004286316 29 Q13423,P48735,Q15120,P21796 4
Nuclear signaling by erbb4 0.416162335350661 0.4112424074283952 0.6808947953393247 1.0 0.9325933004286316 3 P16949,Q92542 2
Toll like receptor cascades 0.4484801217360945 0.4109532961813268 0.6811067811781777 1.0 0.9325933004286316 24 Q06124,P30154,Q15418,P51812,O60443 5
Rhov gtpase cycle 0.4362775614113661 0.406469228871803 0.6843978619654527 1.0 0.9331686370187624 13 Q14155 1
Asparagine n linked glycosylation 0.2811073889018282 0.4026415767275154 0.6872119189191788 1.0 0.9353717785288822 104 P46977,Q9BUN8,Q9Y673,Q9Y678,P53992,Q96PC5,Q5JRA6,Q13561,P68371,P49755,Q9BVA1,P04843,Q13190,Q9BUF5,Q12907,O75935,P27824,Q9HCU5,Q15363,Q9BVK6,Q9BT22,O15027,Q9GZP9,P55735,Q9Y3B3 25
Rnd1 gtpase cycle 0.4291498733062306 0.3908193784972641 0.6959307499660901 1.0 0.9441863254825388 11 P38159,P51648 2
G2 m checkpoints 0.3340854949412996 0.3845483141425121 0.7005720939058033 1.0 0.9469802096933616 75 P49721,P60900,P61289,P28074,Q9UQ84,Q9Y619,O95067,P28072,Q9NXR7,Q14566,Q99436 11
L1cam interactions 0.4418822907744957 0.3762496605098044 0.7067312993755024 1.0 0.9534270823433524 32 P68371,Q9BUF5,Q9BVA1,Q15418 4
Apoptosis 0.2910082362104721 0.3705565862726349 0.7109678225586076 1.0 0.9572599141809712 83 P49721,Q9NR28,P28072,P28074,P60900,P61289,Q99436,P35611,P08670,P31751,O60313,O60443 12
G1 s specific transcription 0.4157410417589158 0.3524111044211406 0.7245299753682661 1.0 0.9653705301466928 9 P00374,Q9Y619 2
Intra golgi and retrograde golgi to er traffic 0.3107822759523575 0.3519573629709322 0.7248702385273365 1.0 0.9653705301466928 79 Q9Y678,Q15363,Q9BVA1,P49755,Q10472,Q13190,Q9BUF5,Q15042,Q8TD16,O75935,P68371,O00461,Q9P2W9,Q9Y3B3,O15260 15
Oncogenic mapk signaling 0.4335997031696794 0.3431453154264272 0.7314891416205951 1.0 0.9684107115901178 24 Q13555,Q02750,Q6RW13,Q9NRY5,P51114,Q53H12,P30086 7
Regulation of runx3 expression and activity 0.4335648958289596 0.3410662995465023 0.7330536708137341 1.0 0.9684107115901178 35 P49721,P60900,P28074,P28072,Q99436 5
Signaling by notch3 0.4083485669735576 0.3406508804988333 0.7333664208033035 1.0 0.9684107115901178 7 P67809 1
Biological oxidations 0.4252429463659157 0.3295897001387632 0.7417100062296562 1.0 0.9719270784546644 42 Q16850,P07099,O43169,Q9NUJ1,Q8TB61 5
Signaling by notch 0.4054685825749903 0.329238677285685 0.7419752908049269 1.0 0.9719270784546644 53 P49721,Q15363,P16615,P60900,P61289,P28074,Q96J02,P28072,Q99436,P67809 10
Aberrant regulation of mitotic exit in cancer due to rb1 defects 0.4114864635416825 0.3277368715134693 0.7431106223139969 1.0 0.9719270784546644 10 Q96DE5,Q9UJX6,Q9UJX4 3
Potential therapeutics for sars 0.4294095642701953 0.3263172015322352 0.7441843749701944 1.0 0.9719270784546644 37 Q99720,P07437,P21964,P15260 4
Opioid signalling 0.421202888608311 0.3249977026546937 0.7451828104161304 1.0 0.9719270784546644 16 O43865,P30154 2
Abc transporter disorders 0.4247501083423451 0.3153206164792027 0.7525182331525835 1.0 0.9766016490202032 40 P49721,Q9BUN8,P60900,P28074,Q9GZP9,P28072,Q99436 7
Defective cftr causes cystic fibrosis 0.4247501083423451 0.3153206164792027 0.7525182331525835 1.0 0.9766016490202032 40 P49721,Q9BUN8,P60900,P28074,Q9GZP9,P28072,Q99436 7
Cell death signalling via nrage nrif and nade 0.4030033358285267 0.3116756126101664 0.7552870636866638 1.0 0.9785211061171886 8 Q14155,Q9NY61,Q14344 3
Abc family proteins mediated transport 0.4125792178076026 0.3095488839826668 0.7569040327303709 1.0 0.979690880100065 48 P49721,Q9BUN8,P60900,P28074,Q9GZP9,P40855,P28072,Q99436 8
Cell cycle checkpoints 0.2738748213157705 0.3059016984524513 0.7596794927344748 1.0 0.9820920486063888 129 P49721,Q9UJX4,P30154,P28074,P60900,P61289,Q9UQ84,Q7L7X3,P55735,Q9NXR7,Q15005,Q8NFH4,Q9Y619,O95067,P28072,Q96DE5,Q14566,Q99436 18
Rhou gtpase cycle 0.4107939911100848 0.2959361894155399 0.7672788130682022 1.0 0.9832629875601504 14 Q14155,O43396 2
Citric acid cycle tca cycle 0.4164066557958106 0.2942765129836162 0.7685466184072902 1.0 0.983624963110823 18 Q13423 1
Negative regulation of notch4 signaling 0.4216246719287412 0.2906705694794202 0.7713032823252286 1.0 0.9862330879312337 38 P49721,P60900,P61289,P28074,P28072,Q99436 6
Cyclin a cdk2 associated events at s phase entry 0.4187519005160734 0.2843624883489214 0.7761326028504665 1.0 0.9891056138902916 40 P49721,P60900,P61289,P28074,P28072,P31751,Q99436 7
E2f mediated regulation of dna replication 0.4018220023202506 0.2830292554233478 0.7771544109138004 1.0 0.9891056138902916 11 Q9Y619 1
Hcmv infection 0.40573527215098 0.2806850330757285 0.7789519893341299 1.0 0.9904746333331104 49 Q9BTX1,Q9BVA1,P61978,Q9BUF5,P55735,P68371,Q8NFH4 7
Resolution of sister chromatid cohesion 0.3811713760945653 0.2739924756264291 0.7840904040600494 1.0 0.9931596588576322 59 Q9BVA1,Q9BUF5,Q7L7X3,P55735,P68371,Q15005,Q8NFH4,O95067 8
Antigen processing cross presentation 0.4078541045853984 0.2732214455270575 0.7846829957738144 1.0 0.9931596588576322 47 P49721,P60900,P28074,Q9UIQ6,P28072,P01889,Q99436,P10321 8
Postmitotic nuclear pore complex npc reformation 0.4161761821936345 0.270970100505118 0.786414028569481 1.0 0.9944332232233436 23 Q9BTX1,Q9BW27,P55735,Q8NFH4,Q92973,Q12769,Q8N1F7 7
Regulation of hmox1 expression and activity 0.4121458324210736 0.2663456757555241 0.7899729989175186 1.0 0.9961791861349591 43 P49721,P60900,P28074,P09601,P28072 5
Collagen formation 0.3962607013354129 0.2623725874200646 0.7930342046571013 1.0 0.9982045218252688 11 Q32P28,P13674 2
Hdl clearance 0.3711743772241987 0.2570273023190665 0.7971576967069272 1.0 1.0 2 Q8WTV0 1
Cdt1 association with the cdc6 orc origin complex 0.4136269262214114 0.2544614117020306 0.7991391121120115 1.0 1.0 39 P49721,P60900,Q9Y619,P28074 4
Foxo mediated transcription 0.3932944247014073 0.2515495848290147 0.8013892311064426 1.0 1.0 11 P31751 1
Apc c cdc20 mediated degradation of cyclin b 0.3930229948307031 0.2505661430431445 0.8021495607109266 1.0 1.0 11 Q96DE5,Q9UJX6,Q9UJX4 3
Host interactions of hiv factors 0.2660543827200732 0.2486143765710537 0.8036590867124285 1.0 1.0 92 P49721,Q9BTX1,P12235,Q8N1F7,P28074,P60900,P55735,Q15369,Q8NFH4,P28072,Q99436 11
Runx1 regulates transcription of genes involved in differentiation of hscs 0.4098702612680345 0.2396521144560692 0.8105999602919121 1.0 1.0 40 P49721,Q03164,P60900,P28074,Q96J02,P28072,Q99436 7
Rho gtpase cycle 0.2675293089637462 0.2295048276523545 0.8184765688356006 1.0 1.0 138 P50402,P51648,Q13505,P42166,Q9UQB8,Q9BT78,Q7L576,P42167,Q96HY6,O15173,Q96CS3,Q86XL3,P08670,Q07065,Q14155,P30519 16
Cellular response to hypoxia 0.408666397647599 0.2271942287477388 0.8202727151618694 1.0 1.0 38 P49721,P60900,P28074,Q15369,P28072,Q99436 6
Depolymerisation of the nuclear lamina 0.3841225947021618 0.2267857007075586 0.8205903832127672 1.0 1.0 10 P50402,P42167 2
Cyclin d associated events in g1 0.3783939116228583 0.2235111846947794 0.8231376791720548 1.0 1.0 8 P30154 1
Signaling by the b cell receptor bcr 0.4039986730435656 0.2191255357657878 0.8265522594503962 1.0 1.0 42 P49721,P60900,P61289,P28074,O43865,P28072,Q99436 7
Regulation of mrna stability by proteins that bind au rich elements 0.3644540611129818 0.2015251923810767 0.8402879328202253 1.0 1.0 61 P49721,Q01105,P61289,P60900,P28074,Q9NQT4,Q14103,Q96B26,P28072,P04792,O00231,Q99436,Q92945 13
Calnexin calreticulin cycle 0.36785929915691 0.1972522622607323 0.843630134539898 1.0 1.0 7 Q9GZP9 1
Intrinsic pathway for apoptosis 0.3911655978043595 0.1969035921105285 0.8439029826138822 1.0 1.0 18 Q9NR28,O60443 2
Hedgehog ligand biogenesis 0.4009910205958408 0.1910625905908146 0.8484765560582663 1.0 1.0 38 P49721,P60900,P28074,Q9GZP9,P28072,Q99436 6
Mitotic g1 phase and g1 s transition 0.3327861533222878 0.1906946304504917 0.8487648457757286 1.0 1.0 70 P49721,P30154,P60900,P28074,Q9Y619,P28072,P31751,Q14566,Q99436 9
Transcriptional regulation by runx3 0.3996841849517549 0.190197966124594 0.8491540048294404 1.0 1.0 40 P49721,P60900,P28074,P28072,Q99436 5
Sphingolipid metabolism 0.3945456757337117 0.1888811043796902 0.8501860035217748 1.0 1.0 22 Q96G23,O95470,O15269,P51648 4
Signaling by notch4 0.3983100479151031 0.187030941689328 0.851636373023039 1.0 1.0 41 P49721,P60900,P61289,P28074,P28072,Q99436 6
Cell cycle 0.2586937881200163 0.184959559473415 0.8532607550944897 1.0 1.0 272 P50402,P60900,Q01105,P61289,Q7L7X3,Q9Y619,Q86XL3,O95067,Q96DE5,O95684,P30154,P28074,O94927,P68371,Q8NFH4,P42167,P28072,Q14566,P07437,Q9BVA1,P42166,Q9BUF5,Q9Y6X3,Q15005,Q8N1F7,O75935,Q9NXR7,Q99436,P49721,Q9BTX1,Q9UJX4,Q9UQ84,P55735,P31751 34
Uch proteinases 0.3960344050822595 0.1843187430649314 0.8537634109863665 1.0 1.0 43 P49721,P60900,Q8NB78,P28074 4
Transcriptional regulation by ventx 0.3760408342293154 0.1766256308213083 0.8598024601195631 1.0 1.0 13 Q96DE5,Q9UJX6,Q9UJX4 3
Auf1 hnrnp d0 binds and destabilizes mrna 0.3968082549668721 0.1766154874791365 0.8598104280818164 1.0 1.0 40 P49721,P60900,P28072,P28074 4
Intra golgi traffic 0.3664730821333773 0.1761157046281881 0.8602030432559731 1.0 1.0 9 O00461 1
Integrin cell surface interactions 0.3514957264957244 0.1745016697400081 0.8614712186373392 1.0 1.0 4 P05556,P35613,Q08722 3
Intracellular signaling by second messengers 0.3147114000719569 0.1740154026136839 0.8618533573766691 1.0 1.0 74 Q13555,P49721,Q06124,P30154,P60900,P28074,O43865,P28072,P31751,Q99436 10
Constitutive signaling by overexpressed erbb2 0.3470986116055561 0.1712631133576767 0.8640168831784214 1.0 1.0 3 Q16543,P62993 2
Regulation of pten stability and activity 0.3960734419564619 0.1705813247905954 0.8645529833425045 1.0 1.0 39 P49721,P60900,P28074,P28072,P31751,Q99436 6
Copi dependent golgi to er retrograde traffic 0.3948502473783431 0.1705379004982097 0.8645871306033552 1.0 1.0 41 Q9Y678,P49755,Q9BVA1,Q9BVK6,Q15363,Q9BUF5,P68371,Q9P2W9,Q9Y3B3,O15260 10
Phosphorylation of the apc c 0.371889400782234 0.1702352426301681 0.8648251366003779 1.0 1.0 12 Q96DE5,Q9UJX6,Q9UJX4 3
Degradation of gli1 by the proteasome 0.3958316764096384 0.1694695947001486 0.8654272863357706 1.0 1.0 39 P49721,P60900,P28074,Q96J02,P28072,Q99436 6
Cross presentation of soluble exogenous antigens endosomes 0.3968803483103079 0.1689588687682741 0.8658289941596795 1.0 1.0 35 P49721,P60900,P28074,P28072,Q99436 5
Degradation of axin 0.3968803483103079 0.1689588687682741 0.8658289941596795 1.0 1.0 35 P49721,P60900,P28074,P28072,Q99436 5
Signaling by erbb2 ecd mutants 0.3472222222222241 0.1619592094673499 0.8713379758315334 1.0 1.0 4 P19174,Q16543,P62993 3
Signaling by egfr in cancer 0.3472222222222241 0.1619592094673499 0.8713379758315334 1.0 1.0 4 P19174,Q16543,P62993 3
Constitutive signaling by ligand responsive egfr cancer variants 0.3472222222222241 0.1619592094673499 0.8713379758315334 1.0 1.0 4 P19174,Q16543,P62993 3
Constitutive signaling by egfrviii 0.3472222222222241 0.1619592094673499 0.8713379758315334 1.0 1.0 4 P19174,Q16543,P62993 3
Signaling by erbb2 in cancer 0.3472222222222241 0.1619592094673499 0.8713379758315334 1.0 1.0 4 P19174,Q16543,P62993 3
Er to golgi anterograde transport 0.3396747460367042 0.1613131350041081 0.8718467785066175 1.0 1.0 67 Q9Y678,P49755,Q9BVA1,Q9HCU5,P53992,Q96PC5,Q15363,Q13190,O15027,Q9BUF5,P55735,P68371,Q12907,Q9Y3B3,O75935 15
Metabolism of polyamines 0.3943603090185318 0.1594061884156795 0.8733488636031856 1.0 1.0 37 P49721,P60900,P28074,P28072,Q99436 5
Scf skp2 mediated degradation of p27 p21 0.3934822017382032 0.1587314861443225 0.8738804303093914 1.0 1.0 39 P49721,P60900,P61289,P28074,P28072,Q99436 6
Hedgehog on state 0.393347050022399 0.1581174369041872 0.8743642607894855 1.0 1.0 39 P49721,P60900,P28074,Q96J02,P28072,Q99436 6
Regulation of pyruvate dehydrogenase pdh complex 0.3498460952030462 0.1507590165848722 0.880165816695915 1.0 1.0 6 Q15120 1
Transcriptional regulation by runx1 0.3472259482666134 0.1463760501422129 0.8836245328751915 1.0 1.0 64 P49721,Q03164,Q06124,P60900,P28074,Q969G3,Q96J02,P28072,Q99436 9
Regulation of glucokinase by glucokinase regulatory protein 0.3875017254821782 0.1430596112276307 0.8862431023445232 1.0 1.0 27 Q9BTX1,Q9BW27,Q9BVL2,P55735,P57740,Q8NFH4,Q12769,Q99567,Q8N1F7,Q9NRG9 10
Sumoylation of ubiquitinylation proteins 0.3875017254821782 0.1430596112276307 0.8862431023445232 1.0 1.0 27 Q9BTX1,Q9BW27,Q9BVL2,P55735,P57740,Q8NFH4,Q12769,Q99567,Q8N1F7,Q9NRG9 10
Sumoylation of sumoylation proteins 0.3875017254821782 0.1430596112276307 0.8862431023445232 1.0 1.0 27 Q9BTX1,Q9BW27,Q9BVL2,P55735,P57740,Q8NFH4,Q12769,Q99567,Q8N1F7,Q9NRG9 10
Hemostasis 0.2606641976629967 0.1352767201394003 0.892393090510049 1.0 1.0 106 O43852,Q07021,Q9NZJ7,P18031,P42785,P33176,P20020,Q9NUQ9,P30154,P68371,P53985,Q9BVA1,P16615,Q06124,Q9BUF5,P35613,Q92896,Q6UXV4,Q92769,Q8NBX0,Q01650 21
Tnf signaling 0.3317906728373124 0.1288116890551748 0.8975066560616409 1.0 1.0 3 P63244,Q15750 2
Tnfr1 induced nfkappab signaling pathway 0.3317906728373124 0.1288116890551748 0.8975066560616409 1.0 1.0 3 P63244,Q15750 2
Nuclear pore complex npc disassembly 0.3862198638891151 0.1280866151337501 0.8980804283708186 1.0 1.0 31 O95067,Q9BTX1,Q8NFH4,P55735 4
Regulation of lipid metabolism by pparalpha 0.3607875412267213 0.1279682760471837 0.8981740786351906 1.0 1.0 13 Q15067,P23786,Q86X55 3
Rhobtb1 gtpase cycle 0.3728655854155491 0.1274749498178293 0.8985644985678312 1.0 1.0 19 P62995,P08670,Q9BT78,P38159 4
Transport to the golgi and subsequent modification 0.3280283930356083 0.1273832493952707 0.8986370732801947 1.0 1.0 69 Q9Y678,P49755,Q9BVA1,Q9HCU5,P53992,Q96PC5,Q15363,Q13190,O15027,Q9BUF5,P55735,P68371,Q12907,Q9Y3B3,O75935 15
Switching of origins to a post replicative state 0.3603242957977433 0.1264123621251549 0.899405517092636 1.0 1.0 58 P49721,Q9UJX4,P60900,P28074,Q9Y619,P28072,Q96DE5,Q14566,Q99436 9
Plasma lipoprotein assembly 0.3266903914590836 0.124994240419468 0.9005281100594866 1.0 1.0 2 P07237 1
Signaling by notch1 0.3445698524967702 0.1191333542153672 0.9051697060642891 1.0 1.0 8 Q96J02 1
Stabilization of p53 0.3845836725538458 0.1172077834610438 0.906695399125054 1.0 1.0 37 P49721,P60900,P28074,P28072,Q99436 5
Clec7a dectin 1 signaling 0.3826427512259598 0.1171414794796238 0.9067479401161128 1.0 1.0 42 P49721,P60900,O43865,P28074 4
Purine ribonucleoside monophosphate biosynthesis 0.3461201475563078 0.1154481287783748 0.908089932707923 1.0 1.0 9 Q06203 1
Mapk6 mapk4 signaling 0.378749469007518 0.1149513454186571 0.9084836870362364 1.0 1.0 46 P49721,P60900,P28072,P28074 4
Unwinding of dna 0.3453442739921556 0.1132947687421135 0.9097968644779496 1.0 1.0 9 Q9Y248,Q9BRT9,P49736,P33991,Q9BRX5,Q14566,P33992,P33993 8
Degradation of dvl 0.3831123497901348 0.1108510638185498 0.9117344517625736 1.0 1.0 36 P49721,P60900,P28074,P28072,Q99436 5
Phosphorylation of emi1 0.3246707013171999 0.1106091784881448 0.9119262687712292 1.0 1.0 3 P53350,P06493 2
Regulation of tp53 activity through acetylation 0.3470894761046959 0.1103552369704068 0.9121276519551692 1.0 1.0 10 P31751 1
Vasopressin regulates renal water homeostasis via aquaporins 0.3269230769230755 0.107128232181121 0.914687250002409 1.0 1.0 4 P63218,P10644,P13861 3
Glucagon signaling in metabolic regulation 0.3269230769230755 0.107128232181121 0.914687250002409 1.0 1.0 4 P63218,P10644,P13861 3
Neurexins and neuroligins 0.3426146067222229 0.1058147403449243 0.9157293413471724 1.0 1.0 9 O14936 1
Insulin processing 0.3334291371011158 0.1057525876911887 0.915778655300568 1.0 1.0 6 P33176,O00471,Q8NEW0 3
Displacement of dna glycosylase by apex1 0.3226056843050702 0.1055176637708332 0.9159650545682962 1.0 1.0 3 P13051 1
Orc1 removal from chromatin 0.37292593912089 0.1041404351240801 0.9170579027045088 1.0 1.0 49 P49721,P60900,P28074,Q9Y619,P28072,Q14566,Q99436 7
G1 s dna damage checkpoints 0.3811516362094734 0.1034304485751393 0.9176213472638124 1.0 1.0 38 P49721,P60900,P28074,P28072,Q99436 5
Ovarian tumor domain proteases 0.3321454027084731 0.102457313232229 0.9183936935896996 1.0 1.0 6 Q14258,P04637,P06493,P55072,Q96FW1 5
Toll like receptor 9 tlr9 cascade 0.3610319720160698 0.1018695801894947 0.9188601958119956 1.0 1.0 17 P51812,Q15418,P30154 3
Asymmetric localization of pcp proteins 0.3805868152612884 0.1005496463293361 0.9199079704387872 1.0 1.0 36 P49721,P60900,P28074,P28072,Q99436 5
Glucagon like peptide 1 glp1 regulates insulin secretion 0.3270395439971473 0.0984544220324895 0.9215714620097688 1.0 1.0 5 P46940,P63218,P10644,P13861 4
Aquaporin mediated transport 0.3270395439971454 0.0984544220324848 0.9215714620097726 1.0 1.0 5 P10644,P63218,Q99797,P13861 4
Smooth muscle contraction 0.3480208556022967 0.0979640978944716 0.9219608019275274 1.0 1.0 12 P04083,P60660,P14649 3
Golgi to er retrograde transport 0.342637045013551 0.0973971332809399 0.922411021217241 1.0 1.0 63 Q9Y678,P49755,Q9BVA1,Q15363,Q10472,Q9Y3B3,Q15042,Q9BUF5,O75935,P68371,Q9P2W9,Q8TD16,O15260 13
Translation of sars cov 2 structural proteins 0.3543458126290212 0.0949507179984882 0.9243539713235748 1.0 1.0 15 P46977,P04843,Q10472 3
Sumoylation of rna binding proteins 0.3774202011208876 0.0907263583736175 0.9277100260461713 1.0 1.0 33 Q9BTX1,P07910,P61978,Q9BW27,P55735,Q8NFH4,Q12769,Q8N1F7,Q9NRG9 9
Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1 0.3736157213022666 0.0906244488229345 0.9277910045143508 1.0 1.0 46 P49721,Q9UJX4,P60900,P61289,P28074,Q9UJX6,O00231,P28072,Q96DE5,Q99436 10
Rho gtpases activate formins 0.3592431994134051 0.083965299850445 0.9330840210169944 1.0 1.0 55 Q9BVA1,Q9BUF5,Q7L7X3,P55735,P68371,Q15005,Q8NFH4 7
Adora2b mediated anti inflammatory cytokines production 0.327272727272725 0.0821798264156519 0.934503715363792 1.0 1.0 7 P04899,P13861,P08754,Q9Y3E5,P10644,P63218 6
Interferon signaling 0.3450346407559533 0.0792261595630409 0.9368527376637816 1.0 1.0 61 Q13555,Q9BTX1,Q06124,P15260,Q9Y3Z3,P55735,Q8NFH4,P01889,P10321 9
Glycogen synthesis 0.3207847217102634 0.0747491376107373 0.940414310840162 1.0 1.0 6 P46976 1
C type lectin receptors clrs 0.3711813854192278 0.0719264385614713 0.9426604496071368 1.0 1.0 44 P49721,P60900,O43865,P28074 4
Apoptotic cleavage of cellular proteins 0.3437329043597913 0.0652896144883114 0.9479434111400746 1.0 1.0 15 P08670 1
Downstream signaling events of b cell receptor bcr 0.3713833844868901 0.064749824693684 0.9483731916549551 1.0 1.0 40 P49721,P60900,P61289,P28074,P28072,Q99436 6
Regulation of ras by gaps 0.3712232535249148 0.0631642559930484 0.949635707504478 1.0 1.0 37 P49721,P60900,P28074,P28072,Q99436 5
Nuclear envelope breakdown 0.3701630100107522 0.0625705973773136 0.9501084434175336 1.0 1.0 42 P50402,Q9BTX1,P42166,P55735,Q8NFH4,P42167,O95067 7
Copii mediated vesicle transport 0.3631710706144779 0.0613821490209383 0.9510548685672447 1.0 1.0 26 P49755,Q15363,P53992,Q13190,O15027,P55735,Q12907 7
Rnd2 gtpase cycle 0.3337313291990979 0.0602263734903914 0.9519753408281976 1.0 1.0 12 P38159,P51648,Q07065 3
Fc epsilon receptor fceri signaling 0.3659837197865968 0.055777628106168 0.9555189573775 1.0 1.0 46 P49721,P60900,O43865,P28074 4
Chk1 chk2 cds1 mediated inactivation of cyclin b cdk1 complex 0.3254817987152096 0.0548603365022055 0.9562497311513722 1.0 1.0 10 P27348,Q04917,O96017,P61981,P06493,Q9Y3B8,P63104,P62258,P31946 9
Regulation of hsf1 mediated heat shock response 0.3626412168026282 0.0544007933913396 0.9566158467577393 1.0 1.0 49 Q9BTX1,P55735,Q99543,Q8NFH4,P04792 5
Programmed cell death 0.2505350229983104 0.0538517419153797 0.9570532852070686 1.0 1.0 95 P49721,Q9NR28,P28072,P28074,P60900,P61289,Q99436,P35611,P08670,P31751,O60313,O60443 12
Interleukin 1 signaling 0.3672551712585986 0.050443466269735 0.95976899938019 1.0 1.0 42 Q02750,P49721,P60900,P28074,P28072,Q99436 6
Synthesis of pi 0.2918149466192245 0.0480395023863201 0.9616847605823988 1.0 1.0 2 O96017 1
Rac2 gtpase cycle 0.3650358778992245 0.0476527596486846 0.961992983637691 1.0 1.0 32 P50402,Q13505,Q7L576,P42167,O15173,Q86XL3 6
Hsf1 dependent transactivation 0.3305462946246925 0.0453723967534492 0.9638104825210958 1.0 1.0 13 P04792 1
Cellular response to heat stress 0.3518961350379077 0.0451968085524091 0.9639504380589125 1.0 1.0 55 Q13555,Q9BTX1,P55735,Q99543,Q8NFH4,P48723,P04792 7
Transport of the slbp dependant mature mrna 0.3623779840911095 0.0441998410276195 0.9647451087727386 1.0 1.0 30 Q9BTX1,Q9UBU9,Q9BW27,P55735,Q8NFH4,Q12769,Q8N1F7,Q9NRG9 8
Fceri mediated nf kb activation 0.3658594362974542 0.0422628231658465 0.96628918160712 1.0 1.0 38 P49721,P60900,P28074,P28072,Q99436 5
Tcr signaling 0.363690303415465 0.0347641139077591 0.9722678362770548 1.0 1.0 41 P49721,P60900,P28074,P28072,Q99436 5
Pre notch expression and processing 0.3069258122356644 0.0294805661217774 0.9764813181929128 1.0 1.0 8 P16615 1
N glycan trimming in the er and calnexin calreticulin cycle 0.3226252289189215 0.026957729379826 0.978493448835593 1.0 1.0 13 Q9BUN8,Q9GZP9 2
Rhoa gtpase cycle 0.3591862773007259 0.01835344444287 0.985356892131948 1.0 1.0 37 P42166,P42167,Q96HY6,O15173,Q96CS3,Q14155,P30519 7
Nef mediated downregulation of mhc class i complex cell surface expression 0.2813390313390284 0.0141686804780055 0.9886954068366004 1.0 1.0 4 O43747,P04439,Q10567 3
Dectin 1 mediated noncanonical nf kb signaling 0.3582034842516484 0.0133862976170854 0.9893195987814264 1.0 1.0 39 P49721,P60900,P28074,P28072,Q99436 5
Tnfr2 non canonical nf kb pathway 0.3582034842516484 0.0133862976170854 0.9893195987814264 1.0 1.0 39 P49721,P60900,P28074,P28072,Q99436 5