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interpro_active_site/advanced/idx2term.json

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+{}

interpro_active_site/basic/idx2term.json

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+{}

interpro_active_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:698b34a41690f06699e7d70e5317a2aefaff5cbb60f3a7057e5556dc142ed6d3
+size 74177

interpro_active_site/df_merge.tsv

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+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_active_site/metrics.json

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+{
+    "type_of_task": "ranksum",
+    "signature_size": 2812,
+    "annotations_size": 55,
+    "title": "Average number of proteins per term",
+    "value": 2.3454545454545452
+}

interpro_active_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C424/C424_val_log2fc"}

interpro_active_site/result.tsv

@@ -0,0 +1,3 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Protein-tyrosine phosphatase, active site [IPR016130]	0.7475423030037595	1.9059118602760496	0.0566616420166723	0.9595692150252766	0.0916585385563817	5	Q06124,Q9Y217	2
+Tyrosine-protein kinase, active site [IPR008266]	0.4866500533997882	0.7114169791273878	0.4768258804312135	0.9999999999999996	0.494819309881448	3	P08069,Q13308	2

interpro_active_site/selections.json

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+{"all_annotations": ["ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenosine/AMP deaminase active site [IPR006650]", "Adenylosuccinate synthase,  active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Coenzyme A transferase active site [IPR004164]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glutaredoxin active site [IPR011767]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycoside hydrolase, family 2, active site [IPR023232]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine proteases, trypsin family, histidine active site [IPR018114]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]", "Uracil-DNA glycosylase, active site [IPR018085]"], "available_proteins": ["ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADSS", "AKT2", "AMPD2", "APEH", "ATP5A1", "ATP5B", "ATP6V1A", "ATP6V1B2", "BLMH", "CAMK2G", "CAPN1", "CAPN2", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CHEK2", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CTSA", "CTSB", "CTSC", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLRX", "GLUD1", "GSR", "GUSB", "HADHB", "HMGCS1", "IGF1R", "LDHA", "LDHB", "LONP1", "MAP2K1", "MAP2K4", "MAPK1", "MDH1", "MDH2", "MTMR6", "NEK9", "NME1", "OXCT1", "PAK2", "PBK", "PGAM1", "PIK3R4", "PKM", "PKN2", "PLK1", "PREP", "PRKAA1", "PRKACA", "PRKCB", "PRPF4B", "PRSS3", "PTK7", "PTPN1", "PTPN11", "PTPRF", "RIPK1", "RNASET2", "ROCK1", "RPS6KA1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SUCLG1", "TALDO1", "TAOK1", "TIGAR", "TOP1", "TPI1", "TPP2", "TXNRD1", "TXNRD2", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2K", "UBE2L3", "UBE2M", "UBE2S", "UMPS", "UNG", "VRK1", "WNK1"], "leading_proteins": ["IGF1R", "MTMR6", "PTK7", "PTPN11"]}

interpro_binding_site/advanced/idx2term.json

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+{}

interpro_binding_site/basic/idx2term.json

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+{"0": "Protein kinase, ATP binding site [IPR017441]"}

interpro_binding_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:2a750efc3cece497fd82e523e0f4b65a7137322718c3347ad21e83515c387c26
+size 67402

interpro_binding_site/df_merge.tsv

@@ -0,0 +1 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_binding_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2812,
+    "annotations_size": 31,
+    "title": "Average number of proteins per term",
+    "value": 3.806451612903226
+}

interpro_binding_site/paths.json

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+{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C424/C424_val_log2fc"}

interpro_binding_site/result.tsv

@@ -0,0 +1,6 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Beta tubulin, autoregulation binding site [IPR013838]	0.9743589743589742	2.8783759263548196	0.0039972848597742	0.1167651593718568	0.0413052768843338	4	P07437,Q9BVA1,P68371	3
+Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]	0.6896797153024917	1.661954654851331	0.096521866778835	0.9570021221938438	0.1662321038968825	2	O15270	1
+EF-Hand 1, calcium-binding site [IPR018247]	0.5384290217989485	0.8920402164261976	0.3723713768252183	0.9999994644685432	0.4275375067252507	32	P80303,Q14257,O43852,Q9BPX6	4
+Protein kinase, ATP binding site [IPR017441]	0.4249879613142504	0.2946602512176263	0.768253430576133	1.0	0.7938618782620042	31	Q13555,Q02750,P31751,Q15418,Q7L7X3,P51812	6
+Peptidase M16, zinc-binding site [IPR001431]	0.2959674514509485	0.0313458679346518	0.9749937110412216	1.0	0.9749937110412216	5	O43847,P22695	2

interpro_binding_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "APOBEC/CMP deaminase, zinc-binding [IPR016192]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Coenzyme A transferase binding site [IPR004163]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]", "Ureohydrolase, manganese-binding site [IPR020855]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "AKT2", "APEX1", "APOBEC3C", "ARG2", "BPNT1", "CALU", "CAMK2G", "CAPN1", "CAPN2", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A2", "CYB5B", "DBT", "DLAT", "DLST", "EHD1", "EHD4", "EIF2AK2", "EPS15", "EPS15L1", "FKBP10", "GCAT", "GOT1", "GOT2", "GPD2", "HK1", "HK2", "HMBS", "IDE", "IGF1R", "ILKAP", "IQGAP1", "IQGAP2", "IQSEC1", "LETM1", "MACF1", "MAP2K1", "MAP2K4", "MAPK1", "MAPK14", "MCCC1", "MICU1", "MYH10", "MYH9", "MYO1B", "MYO1C", "MYO1D", "NRDC", "NUCB1", "NUCB2", "OXCT1", "PA2G4", "PAK2", "PC", "PCCA", "PDCD6", "PEF1", "PGD", "PKN2", "PLCG1", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "PPM1F", "PPM1G", "PRKAA1", "PRKACA", "PRKCB", "PRKCSH", "PSAT1", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK1", "RPS6KA1", "RPS6KA3", "S100A11", "SDHA", "SDHB", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "TAOK1", "TBK1", "TKT", "TUBB", "TUBB2B", "TUBB4B", "TUBB6", "UBE3C", "UQCRC2", "VRK1"], "leading_proteins": ["AKT2", "CALU", "CAMK2G", "MAP2K1", "MICU1", "NRDC", "NUCB2", "RCN2", "RPS6KA1", "RPS6KA3", "SPTLC2", "TAOK1", "TUBB", "TUBB2B", "TUBB4B", "UQCRC2"]}

interpro_conserved_site/advanced/idx2term.json

@@ -0,0 +1 @@
+{}

interpro_conserved_site/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "14-3-3 protein, conserved site [IPR023409]"}

interpro_conserved_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:f11fd59bdfb5a44cbb653d8fe026df514a888eeabb1fb01bec6c423c75ebb3a8
+size 104916

interpro_conserved_site/df_merge.tsv

@@ -0,0 +1,2 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+Proteasome beta-type subunit, conserved site [IPR016050]	3	8	2.103424254989008	0.0354287000581681	3.7135922330097086	7.970873786407767	1.4913184573846054	0.1902243906475925	1.515457478026574	0.1681602725795027	1.0170822776023185	0.2455850375425174	0.0073045224575045	0.0461123069087121	0.0038356556834428	0.0014512760162947	0.0009118158302113

interpro_conserved_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2812,
+    "annotations_size": 259,
+    "title": "Average number of proteins per term",
+    "value": 2.6563706563706564
+}

interpro_conserved_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C424/C424_val_log2fc"}

interpro_conserved_site/result.tsv

@@ -0,0 +1,23 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Tubulin, conserved site [IPR017975]	0.9743589743589742	2.8783759263548196	0.0039972848597742	0.645615039415073	0.0680995721282667	4	P07437,Q9BVA1,P68371	3
+Haem oxygenase conserved site [IPR018207]	0.961209964412814	2.828944238364937	0.00467018352802	0.7025207585554116	0.0680995721282667	2	P30519	1
+Guanylate kinase, conserved site [IPR020590]	0.8283475783475766	2.2683797711751628	0.0233060696342155	0.99777439235867	0.0804836271368243	4	O14936,Q14168,Q9NZW5	3
+Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]	0.7930565378443377	2.1141219392840016	0.0345048537988892	0.999887727199614	0.1015540583399126	4	P48735	1
+Proteasome beta-type subunit, conserved site [IPR016050]	0.7930087995545346	2.103424254989008	0.0354287000581681	0.9999123820791468	0.10231491205195	8	P49721,P28074,P28072	3
+Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]	0.7757208971164249	2.0426132702052024	0.0410907364163739	0.9999809288812848	0.1052150463798231	3	P01889,P04439	2
+Syntaxin/epimorphin, conserved site [IPR006012]	0.7554760599960736	1.9417435569749664	0.0521681528835342	0.9999990593980084	0.1195712530693396	5	Q9P2W9	1
+DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]	0.6889679715302486	1.658700992761141	0.0971760592580728	0.999999999996829	0.1770314262686313	2	O15160	1
+Ubiquitin specific protease, conserved site [IPR018200]	0.6601291415901305	1.4753351469157778	0.1401224616394007	1.0	0.2265066994725471	14	Q96K76,Q8TEY7,P40818	3
+Thioredoxin, conserved site [IPR017937]	0.6536814343773623	1.4505751280931871	0.1468982052115937	1.0	0.2305856675745622	10	Q9H3N1,Q8IXB1,Q9H1E5,O43396	4
+Annexin repeat, conserved site [IPR018252]	0.6161361271243933	1.2831073210839974	0.1994544792212313	1.0	0.2822880334333275	7	P12429,P04083,P50995	3
+Actin, conserved site [IPR004001]	0.5975088967971487	1.2349211167846477	0.2168598635560954	1.0	0.299449663000262	2	O96019	1
+Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]	0.5918149466192159	1.2083001048839015	0.2269318481464353	1.0	0.3077243385860039	2	Q9UNQ2	1
+DnaJ domain, conserved site [IPR018253]	0.5238222983995261	0.8303115792944545	0.406362642941386	1.0	0.4714162691952762	9	Q9NVH1,Q99543,Q9UBS4,Q96KC8	4
+Sterol reductase, conserved site [IPR018083]	0.5099644128113839	0.8279278388180145	0.4077113679526714	1.0	0.4714162691952762	2	Q14739	1
+14-3-3 protein, conserved site [IPR023409]	0.4878831076265084	0.6864183575243016	0.4924493315457794	1.0	0.5474488994473786	6	Q04917,P61981,P31946,P63104,P62258	5
+RNA polymerase, beta subunit, conserved site [IPR007121]	0.4805980776076918	0.684312584379046	0.4937778021043992	1.0	0.5474488994473786	3	P30876,Q9NW08	2
+Aldehyde dehydrogenase, cysteine active site [IPR016160]	0.4737355887024673	0.6144095193546951	0.5389447468634239	1.0	0.5939859125005396	7	P51648	1
+Oxysterol-binding protein, conserved site [IPR018494]	0.4435747931316665	0.5020941899767134	0.6156012669170752	1.0	0.6643363672146769	5	Q9BZF3	1
+Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]	0.4049822064056922	0.3787058514236199	0.7049063076654625	1.0	0.7421574540055073	2	Q00796	1
+Mini-chromosome maintenance, conserved site [IPR018525]	0.3630197521286817	0.1905725871018656	0.8488604688696013	1.0	0.8722717805569966	6	Q14566	1
+Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]	0.275997150997149	0.0060245593198355	0.9951931262109128	1.0	1.0	4	P42345,O00443,P42356	3

interpro_conserved_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Aldose 1-epimerase, conserved site [IPR018052]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Amyloidogenic glycoprotein,  copper-binding domain conserved site [IPR019744]", "Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "CBX family C-terminal motif [IPR033773]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific,  conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "Fibrillarin, conserved site [IPR020813]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glutathione peroxidase conserved site [IPR029760]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 2, conserved site [IPR023230]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site [IPR023076]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "Molybdenum cofactor biosynthesis, conserved site [IPR008284]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NADH:ubiquinone oxidoreductase, subunit 1, conserved site [IPR018086]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M22, conserved site [IPR017860]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P,  conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "Tyrosine-protein kinase, receptor class II, conserved site [IPR002011]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]"], "available_proteins": ["AAAS", "AACS", "AAMP", "ABCB1", "ABCB7", "ABCC1", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ACAA2", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK3", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1M1", "AP2M1", "AP2S1", "AP3M1", "AP3S1", "APEX1", "APLP2", "ARHGEF7", "ARIH2", "ATAD1", "ATAD2", "ATP5C1", "ATP5O", "BAG6", "BAZ1A", "BAZ1B", "BCS1L", "BDH2", "BOP1", "BPNT1", "BPTF", "BRD1", "BRD2", "BUD31", "CAD", "CALR", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CBR1", "CBX1", "CBX3", "CBX5", "CBX8", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDH2", "CDKAL1", "CHAF1B", "CHD1", "CHD1L", "CHD4", "CMPK1", "CNDP2", "COLEC12", "COPA", "COPZ1", "CORO1C", "CPOX", "CRYZ", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CYP51A1", "DCAF13", "DCAF7", "DCPS", "DCXR", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX55", "DDX6", "DHCR7", "DHFR", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX35", "DHX36", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIMT1", "DIS3", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC2", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DRG1", "DRG2", "DSG2", "DTYMK", "DYNLL1", "DYNLL2", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "ENO1", "ENO2", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPRS", "EPS15", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FARP2", "FBL", "FCGRT", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FUCA1", "FUCA2", "GAA", "GALK1", "GALM", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GLA", "GLB1", "GLB1L2", "GLO1", "GMPPA", "GNPDA1", "GNS", "GPHN", "GPI", "GPX8", "GRHPR", "GRWD1", "GSPT1", "GTF3C2", "GUSB", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HGS", "HIBADH", "HINT2", "HLA-A", "HLA-B", "HLTF", "HMGA1", "HMGA2", "HMGB1", "HMGB2", "HMGB3", "HMGCR", "HMOX1", "HMOX2", "HSD17B10", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IGF1R", "ILVBL", "IMPAD1", "IMPDH2", "IQGAP1", "IQGAP2", "IVD", "KDM2A", "KDM5A", "KDSR", "KIF11", "KIF14", "KIF18A", "KIF1A", "KIF1B", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "LAMP1", "LARS", "LARS2", "LBR", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRP1", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK14", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME2", "MFSD14B", "MID1", "MIF", "MKRN2", "MPHOSPH8", "MPI", "MPP2", "MPP6", "MPP7", "MPST", "MRPL13", "MRPL24", "MRPL3", "MRPS11", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "ND1", "NDUFS1", "NDUFS2", "NDUFS3", "NEFM", "NF1", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NSD2", "NSF", "NUDT1", "NUDT12", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL11", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PBRM1", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA6", "PEBP1", "PEPD", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHF3", "PHGDH", "PHIP", "PI4KA", "PIK3C2A", "PLEC", "PLOD1", "PLOD2", "PLRG1", "PLS1", "PLS3", "PNP", "POLA1", "POLD1", "POLR1B", "POLR1C", "POLR2B", "POLR2C", "POLR2E", "POLR3B", "PPIB", "PPIC", "PPID", "PPIF", "PPIH", "PPIL1", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PUS7", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "RACK1", "RAE1", "RANBP2", "RARS", "RCL1", "RDH13", "RDX", "RIDA", "RNF14", "RNF2", "RNF20", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS24", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "RSF1", "RSL24D1", "RTN4IP1", "S100A11", "SART1", "SBDS", "SCAF11", "SCD", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB6", "SERPINH1", "SLC1A5", "SLC27A4", "SLC2A1", "SLIT2", "SMARCA4", "SMU1", "SNRNP40", "SNU13", "SORD", "SPTBN1", "SRCAP", "SRM", "STAM", "STMN1", "STX12", "STX18", "STX4", "STX5", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SV2A", "SYNE2", "TAF5", "TBL3", "TCP1", "TFB1M", "THOC6", "TK1", "TLN1", "TMX1", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRIM21", "TRIM24", "TRIM25", "TRIM28", "TRIM33", "TRIP13", "TRMT11", "TSFM", "TSPAN6", "TST", "TUBB", "TUBB2B", "TUBB4B", "TUBB6", "TUFM", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UBFD1", "UHRF1", "USP10", "USP11", "USP14", "USP19", "USP24", "USP28", "USP33", "USP36", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VAT1", "VCL", "VCP", "VIM", "VPS4A", "VPS4B", "WARS", "WARS2", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR3", "WDR36", "WDR5", "WDR61", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZMYND8"], "leading_proteins": ["ACTL6A", "ALDH3A2", "ANXA1", "ANXA11", "ANXA3", "CASK", "DIMT1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC2", "HLA-A", "HLA-B", "HMOX2", "IDH2", "LBR", "MCM6", "MPP2", "MPP6", "MTOR", "OSBPL6", "PI4KA", "PIK3C2A", "POLR1C", "POLR2B", "POLR3B", "PSMB2", "PSMB5", "PSMB6", "SORD", "STX18", "TMX1", "TMX4", "TUBB", "TUBB2B", "TUBB4B", "TXNL1", "USP33", "USP47", "USP8", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAZ"]}

interpro_domain/advanced/idx2term.json

@@ -0,0 +1 @@
+{}

interpro_domain/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "GOLD domain [IPR009038]", "1": "RNA recognition motif domain, eukaryote [IPR003954]", "2": "DnaJ domain [IPR001623]", "3": "EF-hand domain [IPR002048]", "4": "14-3-3 domain [IPR023410]", "5": "Thioredoxin domain [IPR013766]", "6": "K Homology domain, type 1 [IPR004088]", "7": "K Homology domain [IPR004087]", "8": "RNA recognition motif domain [IPR000504]", "9": "Band 7 domain [IPR001107]"}

interpro_domain/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:d903b6fbd05eeea1f672c8c335dcf109bf28a15575a8446e8c69a3965e73fc65
+size 446927

interpro_domain/df_merge.tsv

@@ -0,0 +1,7 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+Cytochrome b5-like heme/steroid binding domain [IPR001199]	4	5	2.6094504570171084	0.0090687776771443	2.813106796116505	6.104368932038835	1.6405397264547834	0.1100883340733615	1.2852875686886795	0.8042848477475721	1.100790504333474	0.1612592696854457	1.3401087212461636e-05	0.0550816697898294	0.0001725606130307	0.0001383364889708	0.0001575214550341
+Aminopeptidase N-like , N-terminal domain [IPR045357]	4	6	2.0719030355602435	0.0382744848323288	2.121359223300971	5.466019417475728	1.4317001483019938	0.1783942022754649	1.021530403905949	0.5881604361499402	0.986353205880356	0.2226891741813114	0.004624601375411	0.0005968088999726	0.0024164244761899	0.0146338936924203	0.0003286021100258
+Peptidase M1, membrane alanine aminopeptidase [IPR014782]	4	6	2.0719030355602435	0.0382744848323288	2.121359223300971	5.466019417475728	1.4317001483019938	0.1783942022754649	1.021530403905949	0.5881604361499402	0.986353205880356	0.2226891741813114	0.004624601375411	0.0005968088999726	0.0024164244761899	0.0146338936924203	0.0003286021100258
+Guanylate kinase-like domain [IPR008144]	3	5	2.071010991447226	0.0383577688996716	2.9975728155339807	6.963592233009709	0.5006632403339694	0.4738825144563896	2.043814711463587	1.6869386038453082	0.907662015536667	0.3076020117251588	1.0	1.0	1.0	0.3058660732099017	0.0048822579474643
+Guanylate kinase/L-type calcium channel beta subunit [IPR008145]	3	5	2.071010991447226	0.0383577688996716	2.9975728155339807	6.963592233009709	0.5006632403339694	0.4738825144563896	2.043814711463587	1.6869386038453082	0.907662015536667	0.3076020117251588	1.0	1.0	1.0	0.3547863423381785	0.0097510399506001
+Phospholipid/glycerol acyltransferase [IPR002123]	3	5	2.0623568046617664	0.0391737785591121	2.4611650485436893	6.109223300970874	0.4541526786138767	0.3733328307275969	1.647577392422315	1.6678607828333205	1.200305691546449	0.3080828121567173	1.0	1.0	1.0	0.3225700131084155	0.0062633876942655

interpro_domain/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2812,
+    "annotations_size": 2406,
+    "title": "Average number of proteins per term",
+    "value": 2.117206982543641
+}

interpro_domain/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C424/C424_val_log2fc"}

interpro_domain/result.tsv

@@ -0,0 +1,211 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Reticulon [IPR003388]	0.9921708185053386	2.952299165935488	0.0031541717600862	0.9995000142136176	0.0674277867868435	2	Q9NQC3	1
+Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]	0.9743589743589742	2.8783759263548196	0.0039972848597742	0.99993471450197	0.0674277867868435	4	P07437,Q9BVA1,P68371	3
+Tubulin/FtsZ, GTPase domain [IPR003008]	0.9743589743589742	2.8783759263548196	0.0039972848597742	0.99993471450197	0.0674277867868435	4	P07437,Q9BVA1,P68371	3
+FAD linked oxidase, N-terminal [IPR006094]	0.964768683274024	2.843220239207112	0.0044660197779802	0.9999789647193782	0.0674277867868435	2	Q15392	1
+FAD-binding domain, PCMH-type [IPR016166]	0.964768683274024	2.843220239207112	0.0044660197779802	0.9999789647193782	0.0674277867868435	2	Q15392	1
+TRAM/LAG1/CLN8 homology domain [IPR006634]	0.9565836298932396	2.8103473069245903	0.0049488065043599	0.9999934522449588	0.0674277867868435	2	Q15629	1
+Endoplasmic reticulum vesicle transporter, C-terminal [IPR012936]	0.9305785274703232	2.702333858277699	0.0068854586153468	0.9999999396865236	0.0674277867868435	3	Q9Y282	1
+Endoplasmic reticulum vesicle transporter, N-terminal [IPR039542]	0.9305785274703232	2.702333858277699	0.0068854586153468	0.9999999396865236	0.0674277867868435	3	Q9Y282	1
+Ribosomal S6 kinase, N-terminal catalytic domain [IPR041906]	0.9227758007117488	2.673124551158895	0.007514834341864	0.9999999868779316	0.0674277867868435	2	Q15418	1
+Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862]	0.9220640569395052	2.6702104217010953	0.0075803725728831	0.9999999888056268	0.0674277867868435	2	Q32P28	1
+Zinc finger, CHHC-type [IPR012996]	0.9216803132787464	2.665801083791098	0.0076805122596301	0.9999999912187164	0.0674277867868435	3	P31943,P52597	2
+Cytochrome b5-like heme/steroid binding domain [IPR001199]	0.9091556822230116	2.6094504570171084	0.0090687776771443	0.999999999697524	0.0674277867868435	5	O43169,O00264,O15173,Q8WUJ1	4
+GMP phosphodiesterase, delta subunit [IPR008015]	0.9049483802064882	2.596659192991696	0.0094135273372968	0.9999999998690524	0.0674277867868435	3	Q13432,A6NIH7	2
+Peptidase M3A/M3B catalytic domain [IPR001567]	0.9047712671170594	2.595924167163269	0.0094336883196908	0.9999999998753104	0.0674277867868435	3	P52888	1
+Zinc finger C2H2 AKAP95-type [IPR034736]	0.8996084015663983	2.5744691000518314	0.0100394053649566	0.9999999999713788	0.0692221033014298	3	Q9ULX6,O43823	2
+CYRIA/CYRIB, Rac1 binding domain [IPR009828]	0.8971530249110313	2.567552117186184	0.0102419392098433	0.999999999982506	0.0692221033014298	2	Q7L576	1
+Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337]	0.8946619217081851	2.5572149225204557	0.0105514003660358	0.999999999991756	0.0697384572486567	2	O60506	1
+Fragile X-related 1 protein, C-terminal region 1 [IPR032172]	0.8854092526690398	2.5187053105563475	0.0117787191181544	0.999999999999584	0.0719767981810884	2	P51114	1
+LEM-like domain [IPR013146]	0.8846975088967977	2.515735557122162	0.0118784270730039	0.9999999999996736	0.0720348473706707	2	P42167	1
+Acyl-CoA oxidase, C-terminal [IPR002655]	0.8740213523131766	2.471060727624604	0.0134712940253902	0.9999999999999932	0.0744840248494142	2	O15254	1
+ATPase family AAA domain-containing protein 3, N-terminal [IPR021911]	0.8701067615658373	2.454619457232606	0.0141033797213649	0.9999999999999986	0.0754060702435648	2	Q9NVI7	1
+RBM1CTR [IPR012604]	0.8619217081850542	2.420137081810819	0.0155146572238071	1.0	0.0776962901518074	2	P38159	1
+MHC class I alpha chain, alpha1 alpha2 domains [IPR001039]	0.8394446422214354	2.3202786677099696	0.0203258073456831	1.0	0.0827477030012074	3	P01889,P10321	2
+MHC class I, alpha chain, C-terminal [IPR010579]	0.8394446422214354	2.3202786677099696	0.0203258073456831	1.0	0.0827477030012074	3	P01889,P10321	2
+Marvel domain [IPR008253]	0.8370106761565923	2.3143125074613375	0.0206505862100145	1.0	0.0836698993812601	2	O43760	1
+CARG-binding factor, N-terminal [IPR012956]	0.8355871886121009	2.3082253836645292	0.0209866040479418	1.0	0.0844377413701472	2	Q99729	1
+KHDRBS, Qua1 domain [IPR032571]	0.8352313167259774	2.3067029264831937	0.0210713870034977	1.0	0.084496261884026	2	O75525	1
+Sam68, tyrosine-rich domain [IPR032335]	0.8352313167259774	2.3067029264831937	0.0210713870034977	1.0	0.084496261884026	2	O75525	1
+Zinc finger, CW-type [IPR011124]	0.8338078291815059	2.3006103928148507	0.021413663067896	1.0	0.0852914680610176	2	Q8NB78	1
+ERAP1-like C-terminal domain [IPR024571]	0.8305163243109857	2.2777722011716484	0.0227401534015598	1.0	0.0875719461411369	4	Q9UIQ6,P55786	2
+Methyltransferase type 11 [IPR013216]	0.8281138790035566	2.2761969811757385	0.0228342225268298	1.0	0.0875719461411369	2	Q8N6R0	1
+L27 domain, C-terminal [IPR014775]	0.8283475783475766	2.2683797711751628	0.0233060696342155	1.0	0.0879110598629028	4	O14936,Q14168,Q9NZW5	3
+L27 domain [IPR004172]	0.8283475783475766	2.2683797711751628	0.0233060696342155	1.0	0.0879110598629028	4	O14936,Q14168,Q9NZW5	3
+Ion transporter-like, CBS domain [IPR044751]	0.8103202846975106	2.1994591253592857	0.0278452924809453	1.0	0.0966873840358497	2	Q8NE01	1
+CNNM, transmembrane domain [IPR002550]	0.8103202846975106	2.1994591253592857	0.0278452924809453	1.0	0.0966873840358497	2	Q8NE01	1
+Cation-transporting P-type ATPase, C-terminal [IPR006068]	0.8095407618369541	2.1910552028053876	0.0284477979390365	1.0	0.097354979552734	3	P20020,P16615	2
+Cation-transporting P-type ATPase, N-terminal [IPR004014]	0.8095407618369541	2.1910552028053876	0.0284477979390365	1.0	0.097354979552734	3	P20020,P16615	2
+Isopropylmalate dehydrogenase-like domain [IPR024084]	0.7930565378443377	2.1141219392840016	0.0345048537988892	1.0	0.1042640205849911	4	P48735	1
+Nucleotidyl transferase domain [IPR005835]	0.7850533807829199	2.089335333365129	0.0366775478901686	1.0	0.1073554503938512	2	Q96IJ6	1
+Aminopeptidase N-like , N-terminal domain [IPR045357]	0.7854626481670466	2.0719030355602435	0.0382744848323288	1.0	0.1089558407161945	6	P09960,Q9NZ08,Q9UIQ6,P55786	4
+Peptidase M1, membrane alanine aminopeptidase [IPR014782]	0.7854626481670466	2.0719030355602435	0.0382744848323288	1.0	0.1089558407161945	6	P09960,Q9NZ08,Q9UIQ6,P55786	4
+Guanylate kinase-like domain [IPR008144]	0.784341146535358	2.071010991447226	0.0383577688996716	1.0	0.1089558407161945	5	O14936,Q14168,Q9NZW5	3
+Guanylate kinase/L-type calcium channel beta subunit [IPR008145]	0.784341146535358	2.071010991447226	0.0383577688996716	1.0	0.1089558407161945	5	O14936,Q14168,Q9NZW5	3
+FAD dependent oxidoreductase [IPR006076]	0.7814168743325223	2.067783115442334	0.0386604221029063	1.0	0.1089558407161945	3	P43304,Q96CU9	2
+Phospholipid/glycerol acyltransferase [IPR002123]	0.7823964319507879	2.0623568046617664	0.0391737785591121	1.0	0.1095494860548001	5	Q8NF37,O15228,Q99943	3
+MHC class I-like antigen recognition-like [IPR011161]	0.7759971509971415	2.0386036687360183	0.0414895987924042	1.0	0.113699493332728	4	P01889,P04439,P10321	3
+Immunoglobulin C1-set [IPR003597]	0.7759971509971415	2.0386036687360183	0.0414895987924042	1.0	0.113699493332728	4	P01889,P04439,P10321	3
+Tim44-like domain [IPR007379]	0.7729537366548063	2.0361239505475774	0.0417379102926118	1.0	0.1141152410954819	2	O43615	1
+PTB/PI domain [IPR006020]	0.7737090549671737	2.0337069612753953	0.0419811498760587	1.0	0.1145200074850309	3	Q9UKG1	1
+Tyrosine-specific protein phosphatase, PTPase domain [IPR000242]	0.7625502358688186	1.9841547932454071	0.0472385863902424	1.0	0.1230247913028024	3	Q06124	1
+Dynamin, GTPase domain [IPR001401]	0.760876236748181	1.976698989064151	0.0480756651574729	1.0	0.1243763982461074	3	O60313	1
+PITH domain [IPR010400]	0.7551601423487577	1.9573203802565473	0.0503098128476318	1.0	0.126558753878156	2	O43396	1
+Far upstream element-binding protein, C-terminal [IPR015096]	0.7526690391459232	1.9462361348879016	0.051626381188762	1.0	0.1285205453579767	2	Q92945	1
+Protein kinase, C-terminal [IPR017892]	0.7520135775230343	1.9261214904663075	0.0540892058224757	1.0	0.1322547044805657	5	P51812,Q15418	2
+AWS domain [IPR006560]	0.746263345195737	1.9176761597923624	0.0551520864667938	1.0	0.1339010293028314	2	O96028	1
+GRAM domain [IPR004182]	0.7466280541169703	1.9130075983157877	0.0557470797294128	1.0	0.1343293480785064	3	Q66K14	1
+GOLD domain [IPR009038]	0.7409950931769254	1.8665963035256232	0.0619579841930555	1.0	0.140646458194063	8	P49755,Q15363,Q9Y3A6,O76054,Q9Y3B3	5
+Ariadne domain [IPR045840]	0.7213523131672634	1.8058366506872712	0.0709438587153989	1.0	0.1525388061387399	2	O95376	1
+Legume-like lectin [IPR005052]	0.7163701067615826	1.7833250276447823	0.0745334096050942	1.0	0.1572346979590094	2	Q12907	1
+Protein-tyrosine phosphatase, catalytic [IPR003595]	0.7161294244889109	1.762812653829845	0.0779320925164919	1.0	0.162482335004055	5	Q06124,Q9Y217	2
+Ataxin-2, C-terminal [IPR009818]	0.7129015222411115	1.7541098804933972	0.0794116809814151	1.0	0.1647107796907628	4	Q9BPZ3	1
+Acyltransferase, C-terminal domain [IPR032098]	0.7096085409252733	1.7526993542940958	0.0796536266153902	1.0	0.1649521008859293	2	Q92604	1
+Tyrosine-specific protein phosphatases domain [IPR000387]	0.7121669331045811	1.7507519174346036	0.0799886522259927	1.0	0.1649521008859293	4	Q06124	1
+ATP-sulfurylase PUA-like domain [IPR025980]	0.7074733096085392	1.7430105961312403	0.081331763933369	1.0	0.1652738378578428	2	O43252	1
+Sulphate adenylyltransferase [IPR002650]	0.7074733096085392	1.7430105961312403	0.081331763933369	1.0	0.1652738378578428	2	O43252	1
+Sulphate adenylyltransferase catalytic domain [IPR024951]	0.7074733096085392	1.7430105961312403	0.081331763933369	1.0	0.1652738378578428	2	O43252	1
+Prolyl 4-hydroxylase, alpha subunit [IPR006620]	0.706385621140973	1.7242897856868435	0.084655542319985	1.0	0.1693110846399701	4	Q32P28	1
+Oxoglutarate/iron-dependent dioxygenase [IPR005123]	0.7063856211409728	1.7242897856868435	0.084655542319985	1.0	0.1693110846399701	4	Q32P28	1
+Fxr1, tudor domain [IPR041560]	0.7020224742342613	1.7110358662180072	0.0870744920462542	1.0	0.1718631893874387	3	P51114	1
+Fragile X-related 1 protein, C-terminal core [IPR022034]	0.7020224742342613	1.7110358662180072	0.0870744920462542	1.0	0.1718631893874387	3	P51114	1
+Synaptic functional regulator FMRP, KH0 domain [IPR040472]	0.7020224742342613	1.7110358662180072	0.0870744920462542	1.0	0.1718631893874387	3	P51114	1
+Agenet-like domain [IPR008395]	0.7020224742342613	1.7110358662180072	0.0870744920462542	1.0	0.1718631893874387	3	P51114	1
+AGC-kinase, C-terminal [IPR000961]	0.699644351466514	1.677456360386551	0.0934532762039317	1.0	0.180044345362947	7	P51812,Q15418	2
+LEM domain [IPR003887]	0.6981294390557212	1.674013186240746	0.0941280078611652	1.0	0.1810327633205145	6	Q86XL3,P50402,P42167	3
+DNA-directed RNA polymerase, insert domain [IPR011262]	0.6889679715302486	1.658700992761141	0.0971760592580728	1.0	0.1845348055050696	2	O15160	1
+DNA-directed RNA polymerase, RpoA/D/Rpb3-type [IPR011263]	0.6889679715302486	1.658700992761141	0.0971760592580728	1.0	0.1845348055050696	2	O15160	1
+SET domain [IPR001214]	0.6909710062047805	1.6407562039247767	0.1008480328435543	1.0	0.1889722484591836	6	Q03164,Q9H7B4	2
+Cold-shock (CSD) domain [IPR019844]	0.6814712533951122	1.6167597598849277	0.1059301486632366	1.0	0.195196279713092	3	P67809	1
+Post-SET domain [IPR003616]	0.6829997844156975	1.6166473593344612	0.1059544228201572	1.0	0.195196279713092	4	Q03164	1
+Ubiquitin carboxyl-terminal hydrolase, C-terminal [IPR029346]	0.6704626334519559	1.5738151982153292	0.1155301793809298	1.0	0.2047848581065296	2	P51784	1
+Sec7 domain [IPR000904]	0.6701067615658353	1.5721774958542245	0.1159093929667776	1.0	0.2049066858766105	2	Q6DN90	1
+MOSC, N-terminal beta barrel [IPR005303]	0.669395017793593	1.568901517342829	0.1166708882801317	1.0	0.2050475947421453	2	Q5VT66	1
+Molybdenum cofactor sulfurase, C-terminal [IPR005302]	0.669395017793593	1.568901517342829	0.1166708882801317	1.0	0.2050475947421453	2	Q5VT66	1
+P-type ATPase, haloacid dehalogenase domain [IPR044492]	0.6593489306613693	1.499653157996053	0.1337042701961508	1.0	0.2250947057042926	5	Q9HD20,P16615,P20020	3
+CAP Gly-rich domain [IPR000938]	0.6550373798504916	1.4945111552000412	0.1350420684595676	1.0	0.2263370586602594	3	Q99426,Q15813	2
+ABC transporter type 1, transmembrane domain [IPR011527]	0.6565183678245435	1.4936976034233036	0.1352546752286061	1.0	0.2264598111343259	4	O75027,P33527	2
+Alpha/beta hydrolase fold-1 [IPR000073]	0.6558120491629768	1.4904045261330887	0.1361179031541708	1.0	0.2272725017272276	4	P07099	1
+Thiamine pyrophosphate enzyme, C-terminal TPP-binding [IPR011766]	0.6480427046263321	1.4702860428592943	0.1414842995306435	1.0	0.2329987848533391	2	Q9UJ83	1
+Thiamine pyrophosphate enzyme, central domain [IPR012000]	0.6480427046263321	1.4702860428592943	0.1414842995306435	1.0	0.2329987848533391	2	Q9UJ83	1
+Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain [IPR012001]	0.6480427046263321	1.4702860428592943	0.1414842995306435	1.0	0.2329987848533391	2	Q9UJ83	1
+RNA polymerase Rpb2, domain 4 [IPR007646]	0.6441281138790012	1.4521411520205625	0.1464623615124867	1.0	0.2375508760289875	2	Q9NW08	1
+RNA polymerase Rpb2, domain 5 [IPR007647]	0.6441281138790012	1.4521411520205625	0.1464623615124867	1.0	0.2375508760289875	2	Q9NW08	1
+Nucleoporin, Nup133/Nup155-like, C-terminal [IPR007187]	0.6316725978647652	1.3942900281641668	0.1632300409451281	1.0	0.2517646660816643	2	Q8WUM0	1
+Chromo domain subgroup [IPR017984]	0.6333609459539082	1.3935676063280278	0.1634482163007313	1.0	0.2517646660816643	3	P83916	1
+Chromo shadow domain [IPR008251]	0.6333609459539082	1.3935676063280278	0.1634482163007313	1.0	0.2517646660816643	3	P83916	1
+Myb domain [IPR017930]	0.6309534570239613	1.353668798071186	0.1758420669581391	1.0	0.2625351215902535	7	Q99543	1
+Damage-control phosphatase ARMT1-like, metal-binding domain [IPR002791]	0.622775800711755	1.3528708873543316	0.1760968814362002	1.0	0.2626714796872274	2	Q9NVE7	1
+Immunoglobulin-like domain [IPR007110]	0.6311673185329723	1.3420474658581636	0.1795806058498339	1.0	0.2660535330509239	10	P35613,P01889,P04439,P10321	4
+EF-hand, Ca insensitive [IPR014837]	0.6214170548118115	1.3377351699223774	0.1809827819031446	1.0	0.2676364924763159	3	O43707	1
+PB1 domain [IPR000270]	0.6128113879003655	1.3064024791307378	0.1914157232232096	1.0	0.2776047197559026	2	Q13501	1
+Peptidase C19, ubiquitin carboxyl-terminal hydrolase [IPR001394]	0.6198233373617944	1.275251858423034	0.2022201113922632	1.0	0.2886788933027315	15	Q96K76,Q8TEY7,P40818	3
+Ubiquitin specific protease domain [IPR028889]	0.6198233373617944	1.275251858423034	0.2022201113922632	1.0	0.2886788933027315	15	Q96K76,Q8TEY7,P40818	3
+NOPS [IPR012975]	0.6063798774960554	1.2672865053577396	0.2050528639641964	1.0	0.2906485814808111	3	Q15233	1
+Rab-GTPase-TBC domain [IPR000195]	0.6015167576229822	1.2193095360792905	0.2227267305727001	1.0	0.306392517871879	6	Q66K14	1
+Major facilitator superfamily domain [IPR020846]	0.5999365093641392	1.211803298817775	0.2255876852612828	1.0	0.3090910995094797	6	Q8NHS3,Q14728,Q5SR56	3
+Ribosomal RNA adenine methylase transferase, N-terminal [IPR020598]	0.5918149466192159	1.2083001048839015	0.2269318481464353	1.0	0.3102261515001837	2	Q9UNQ2	1
+START domain [IPR002913]	0.5896797153024851	1.1983155164208306	0.2307942082211522	1.0	0.3133695626298489	2	Q9NQZ5	1
+Glycosyltransferase 2-like [IPR001173]	0.5841856179526821	1.1453027020079436	0.2520837870843444	1.0	0.3326780588464016	5	Q86SF2,Q9Y673,Q10472	3
+N-acetylgalactosaminyltransferase [IPR045885]	0.5790064061809759	1.138822531832129	0.2547771819803508	1.0	0.3353650997168132	3	Q10472	1
+Sec63 domain [IPR004179]	0.5789950491769846	1.1387692294523135	0.2547994190699645	1.0	0.3353650997168132	3	Q9UGP8	1
+Acyl-CoA oxidase/dehydrogenase, central domain [IPR006091]	0.5857906066030293	1.1271093170829636	0.2596962645612386	1.0	0.3397657490670691	9	O15254,Q709F0,Q92947	3
+CBS domain [IPR000644]	0.5761025890142477	1.1070699262776584	0.2682636967539946	1.0	0.345341067089412	5	Q8NE01	1
+Exoribonuclease, phosphorolytic domain 1 [IPR001247]	0.5765802134903752	1.100853301914188	0.2709605090097038	1.0	0.3482537311310617	6	Q96B26,Q9NQT4	2
+Cold-shock protein, DNA-binding [IPR002059]	0.5707958715367148	1.0909675309971414	0.2752871699002575	1.0	0.3512900128505768	4	P67809	1
+Cold shock domain [IPR011129]	0.5707958715367148	1.0909675309971414	0.2752871699002575	1.0	0.3512900128505768	4	P67809	1
+PABP, RNA recognition motif 2 [IPR045305]	0.557295373665478	1.0469775189862296	0.2951099468432363	1.0	0.3674870416441775	2	Q13310	1
+Phox homology [IPR001683]	0.5600589610921787	1.0091840432735804	0.3128863777869028	1.0	0.3800124305680405	8	Q96L92	1
+EF hand associated, type-2 [IPR013567]	0.5473309608540867	1.0005475411126368	0.3170456025665835	1.0	0.3814047766026918	2	Q8IXI1	1
+MIRO domain [IPR020860]	0.5473309608540867	1.0005475411126368	0.3170456025665835	1.0	0.3814047766026918	2	Q8IXI1	1
+EF hand associated, type-1 [IPR013566]	0.5473309608540867	1.0005475411126368	0.3170456025665835	1.0	0.3814047766026918	2	Q8IXI1	1
+Exoribonuclease, phosphorolytic domain 2 [IPR015847]	0.5508698606876694	0.987982235754188	0.323161348285957	1.0	0.3875788131734518	5	Q9NQT4	1
+SCP2 sterol-binding domain [IPR003033]	0.5339978640085463	0.928331221457414	0.3532357835096231	1.0	0.4113675194211778	3	P51659,Q6YN16	2
+Myosin tail [IPR002928]	0.5306049822064037	0.9229187597524304	0.3560495435426212	1.0	0.4132453751809019	2	P35580	1
+EB1, C-terminal [IPR004953]	0.5266903914590771	0.9048238348044066	0.3655587224581165	1.0	0.4208298020259465	2	Q15555	1
+RNA recognition motif domain, eukaryote [IPR003954]	0.540356394422123	0.8878045862476287	0.374645875513157	1.0	0.4267982843203862	13	Q96E39,Q14011,P31483,Q9UHX1,P38159	5
+PTBP1, RNA recognition motif 2-like [IPR021790]	0.5185053380782945	0.8671017700696871	0.3858862508486311	1.0	0.4356838665142217	2	P14866	1
+DnaJ domain [IPR001623]	0.5352614609881722	0.849020538049726	0.3958698641396823	1.0	0.4434704077284092	17	Q13217,Q9UBS4,Q9UGP8,Q99543,Q8IXB1,Q96KC8,O14976	7
+MoaB/Mog domain [IPR001453]	0.512455516014225	0.8393317747134904	0.4012831573109654	1.0	0.4473991086608817	2	Q9NQX3	1
+Immunoglobulin I-set [IPR013098]	0.5087219651121389	0.8116267641887207	0.4170058290139971	1.0	0.4602367085356316	3	Q8WX93,P10586	2
+OCRE domain [IPR041591]	0.5017793594305955	0.790598090460686	0.4291785615031731	1.0	0.4697923653214897	2	P98175	1
+Alcohol dehydrogenase-like, C-terminal [IPR013149]	0.5021627945805683	0.7435375084332095	0.4571563215343865	1.0	0.4979258078821793	7	Q8N8N7,Q8N4Q0	2
+AMP-binding enzyme, C-terminal domain [IPR025110]	0.4909220363118624	0.7306550188307073	0.4649898969220771	1.0	0.5062288199070215	3	P33121,Q4G176	2
+SANT domain [IPR017884]	0.5022975539710777	0.7293182924787239	0.4658069852788626	1.0	0.5068890124744204	9	Q99543	1
+Glutaredoxin, PICOT-like [IPR033658]	0.4879003558718858	0.7278683870683094	0.4666941565712506	1.0	0.5076248375725266	2	Q86SX6	1
+EF-hand domain [IPR002048]	0.4973106882736101	0.7237457790116683	0.4692218225474773	1.0	0.5101435630588479	40	Q96AY3,O43852,Q66K14,Q8IYU8,Q14257,Q8NF37,P80303,Q15293,Q9UJS0,Q9BPX6	10
+Tyrosine-protein kinase, catalytic domain [IPR020635]	0.4864768683274062	0.7214805392021257	0.4706139098619286	1.0	0.5114259562456189	2	P08069	1
+ATP-dependent RNA helicase Ski2, C-terminal [IPR012961]	0.4832740213523034	0.7071422786915822	0.4794780645583558	1.0	0.5196505510483802	2	P42285	1
+rRNA-processing arch domain [IPR025696]	0.4832740213523034	0.7071422786915822	0.4794780645583558	1.0	0.5196505510483802	2	P42285	1
+ZU5 domain [IPR000906]	0.482562277580071	0.7039626427882043	0.4814560383690551	1.0	0.5215593103628756	2	Q12955	1
+Kinesin-like KIF1-type [IPR022140]	0.481850533807831	0.7007854792123897	0.4834369013821371	1.0	0.5232340012260107	2	O60333	1
+C2 domain [IPR000008]	0.4946383903441283	0.6938387738783771	0.4877833235127475	1.0	0.5269899759190259	9	Q96PU5,Q99829,Q96J02	3
+Kinesin-like [IPR022164]	0.4820220719117141	0.6906736109259743	0.4897706766110867	1.0	0.5286622915775482	3	O60333,Q9Y3P9	2
+Kinesin-associated [IPR032405]	0.4820220719117024	0.6906736109259214	0.48977067661112	1.0	0.5286622915775482	3	O60333,Q15058	2
+Zinc finger, RanBP2-type [IPR001876]	0.4931291012451886	0.6868805674901803	0.4921579935298303	1.0	0.5307629459582124	9	Q92804	1
+14-3-3 domain [IPR023410]	0.4878831076265084	0.6864183575243016	0.4924493315457794	1.0	0.5308391987899397	6	Q04917,P61981,P31946,P63104,P62258	5
+RNA polymerase, beta subunit, protrusion [IPR007644]	0.4805980776076918	0.684312584379046	0.4937778021043992	1.0	0.5308442322891799	3	P30876,Q9NW08	2
+RNA polymerase Rpb2, domain 7 [IPR007641]	0.4805980776076918	0.684312584379046	0.4937778021043992	1.0	0.5308442322891799	3	P30876,Q9NW08	2
+DNA-directed RNA polymerase, subunit 2, hybrid-binding domain [IPR007120]	0.4805980776076918	0.684312584379046	0.4937778021043992	1.0	0.5308442322891799	3	P30876,Q9NW08	2
+RNA polymerase Rpb2, domain 2 [IPR007642]	0.4805980776076918	0.684312584379046	0.4937778021043992	1.0	0.5308442322891799	3	P30876,Q9NW08	2
+RNA polymerase Rpb2, domain 3 [IPR007645]	0.4805980776076918	0.684312584379046	0.4937778021043992	1.0	0.5308442322891799	3	P30876,Q9NW08	2
+RING-type zinc-finger, LisH dimerisation motif [IPR027370]	0.4768683274021351	0.6786167816550678	0.4973807068922653	1.0	0.5344787765890087	2	O15344	1
+G-protein, beta subunit [IPR001632]	0.4722419928825625	0.6581492493509211	0.5104422321171502	1.0	0.5472923397833617	2	Q9NVX2	1
+Sterile alpha motif domain [IPR001660]	0.4766468301581773	0.635867356900496	0.5248628805608786	1.0	0.5622529343853401	6	Q9Y3Z3	1
+Cyclic nucleotide-binding domain [IPR000595]	0.4693732193732339	0.6239227072532412	0.532678346907868	1.0	0.5691048413234149	4	Q9Y4G8,P13861,Q6P4Q7	3
+FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]	0.471850234392259	0.5978820706914657	0.5499186239617657	1.0	0.5866220153595681	8	Q96AY3,P62942	2
+Thioredoxin domain [IPR013766]	0.4846341261170191	0.586349926513944	0.5576403865541497	1.0	0.5944200872185523	23	Q6ZRP7,Q9Y320,O43819,Q8IXB1,Q9H3N1,Q9H1E5,O43396	7
+PDZ domain [IPR001478]	0.4775914616109403	0.5836103410914214	0.5594825011828817	1.0	0.5956260609938112	14	O14936,Q96L92,Q9NZW5,Q14168	4
+Helicase/UvrB, N-terminal [IPR006935]	0.4516014234875458	0.5684221092381678	0.5697483813031488	1.0	0.6062868666144962	2	P19447	1
+DNA2/NAM7 helicase-like, C-terminal [IPR041679]	0.4519230769230978	0.5480546641696566	0.5836543687243045	1.0	0.6199878194925724	4	P42694,O60306,Q9HCE1	3
+Exosome complex component, N-terminal domain [IPR025721]	0.4437722419928843	0.5351714090951112	0.592531334720293	1.0	0.6285848286318452	2	Q13868	1
+Protein kinase C-like, phorbol ester/diacylglycerol-binding domain [IPR002219]	0.44764957264957	0.5298175865070451	0.5962384106428225	1.0	0.6322387025150422	4	P05771,Q13464,Q9H0H5	3
+Glutathione S-transferase, N-terminal [IPR004045]	0.4543414797640404	0.5291662502143393	0.5966901267388309	1.0	0.632438962525827	7	Q8TB36,Q9H7Z7	2
+ARID DNA-binding domain [IPR001606]	0.4410822356710611	0.5128199137553064	0.6080772985563916	1.0	0.6433746615332798	3	O14497,Q8IVW6	2
+BAT2, N-terminal [IPR009738]	0.4352313167259807	0.4994677981231042	0.6174498669533777	1.0	0.652430557703042	2	Q9Y520	1
+HECT domain [IPR000569]	0.4458855072614579	0.4844801085512557	0.6280451778679694	1.0	0.6630437463581985	8	Q96PU5,Q96J02	2
+Gamma tubulin complex component protein, N-terminal [IPR041470]	0.4295373665480439	0.476024512947478	0.6340569143459334	1.0	0.6685104890080262	2	Q9BSJ2	1
+Gamma tubulin complex component, C-terminal [IPR040457]	0.4295373665480439	0.476024512947478	0.6340569143459334	1.0	0.6685104890080262	2	Q9BSJ2	1
+Peptidase M16, middle/third domain [IPR032632]	0.4209964412811361	0.441444527525516	0.6588912124902542	1.0	0.6925697934694415	2	O43847	1
+K Homology domain, type 1 [IPR004088]	0.4549416945348454	0.4395514473228314	0.6602620125134038	1.0	0.6934048023165645	25	P51116,Q96I24,P61978,Q07666,O75525,P51114,O75179,Q92945	8
+Brix domain [IPR007109]	0.4271464196651117	0.4340614107914093	0.6642438468931955	1.0	0.6969780617640768	5	Q96G21,Q8TDN6,Q9NQ55,Q9H9Y2	4
+K Homology domain [IPR004087]	0.4511600886099293	0.4234451883569107	0.671970481254708	1.0	0.7047781071921655	24	P51116,Q96I24,P61978,Q07666,O75525,P51114,O75179,Q92945	8
+Acyl-CoA dehydrogenase/oxidase C-terminal [IPR009075]	0.428752171074678	0.4215092780764102	0.6733832376097151	1.0	0.7056446296554767	7	Q92947	1
+Acyl-CoA dehydrogenase/oxidase, N-terminal [IPR013786]	0.428752171074678	0.4215092780764102	0.6733832376097151	1.0	0.7056446296554767	7	Q92947	1
+Syntaxin, N-terminal domain [IPR006011]	0.4175863296546827	0.4168753860093724	0.6767695581258417	1.0	0.7082677498263485	3	O15400,Q86Y82	2
+NLE [IPR012972]	0.4106761565836286	0.4006796089235997	0.6886560255013401	1.0	0.7191434016303057	2	Q9NVX2	1
+PurM-like, N-terminal domain [IPR016188]	0.4039145907473349	0.374628949393482	0.7079364399640211	1.0	0.737357175131357	2	P49903	1
+PurM-like, C-terminal domain [IPR010918]	0.4040583837664668	0.3643089545359495	0.7156273139093632	1.0	0.7447228880907992	3	P49903,O15067	2
+Protein of unknown function DUF3715 [IPR022188]	0.3989323843416422	0.3557901648363981	0.7219977151046608	1.0	0.7497309031255132	2	Q9UK61	1
+RNA recognition motif domain [IPR000504]	0.2763092876689826	0.3362250794889633	0.7367011419870217	1.0	0.764009891215851	112	P23588,Q96E39,P62995,Q15233,O60506,P51991,P22626,Q92804,P52597,P31483,Q14011,O43390,P31942,O14979,Q96PK6,Q9BWF3,Q13242,Q99729,Q9UHX1,Q01844,Q01085,P31943,Q14103,P55795,P07910,Q16629,P35637,P38159,Q07955,Q9Y6M1	30
+SANT/Myb domain [IPR001005]	0.4153440116787637	0.3351297543632125	0.7375272086330702	1.0	0.7645370374714204	11	Q99543	1
+Band 7 domain [IPR001107]	0.4035650623885906	0.3224463101450049	0.7471146056202917	1.0	0.7738087564022479	7	Q14254,O75955,O94905,O75477,Q99623,Q9UJZ1	6
+Peptidase M16, C-terminal [IPR007863]	0.4011783024968606	0.3134788205919768	0.7539169091174696	1.0	0.7798469833777436	7	O43847,P22695,Q5JRX3	3
+Peptidase M16, N-terminal [IPR011765]	0.4011783024968606	0.3134788205919768	0.7539169091174696	1.0	0.7798469833777436	7	O43847,P22695,Q5JRX3	3
+Heat shock chaperonin-binding [IPR006636]	0.3812744749021035	0.2810908700199173	0.778640703651559	1.0	0.8037663198671436	3	P54727,Q9NRR5	2
+GYF domain [IPR003169]	0.3779359430605064	0.2800494005262378	0.7794396044451428	1.0	0.8041731081882563	2	O95400	1
+Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding [IPR013155]	0.3854649091556799	0.2752895167009036	0.7830938179017721	1.0	0.8064445249746239	5	Q9P2J5,Q15031,P41252,Q9NSE4	4
+Aminoacyl-tRNA synthetase, class Ia [IPR002300]	0.3854649091556799	0.2752895167009036	0.7830938179017721	1.0	0.8064445249746239	5	Q9P2J5,Q15031,P41252,Q9NSE4	4
+NAD-dependent epimerase/dehydratase [IPR001509]	0.3592025631897499	0.2078933703682952	0.8353122257663497	1.0	0.8544903125824138	3	Q9NRG7,Q13630	2
+MCM N-terminal domain [IPR027925]	0.3630197521286817	0.1905725871018656	0.8488604688696013	1.0	0.8653741877393618	6	Q14566	1
+MCM domain [IPR001208]	0.3630197521286817	0.1905725871018656	0.8488604688696013	1.0	0.8653741877393618	6	Q14566	1
+MCM OB domain [IPR033762]	0.3630197521286817	0.1905725871018656	0.8488604688696013	1.0	0.8653741877393618	6	Q14566	1
+MCM, AAA-lid domain [IPR041562]	0.3630197521286817	0.1905725871018656	0.8488604688696013	1.0	0.8653741877393618	6	Q14566	1
+RasGAP protein, C-terminal [IPR000593]	0.3473309608540923	0.1818297775863136	0.8557163149153915	1.0	0.8705511432077936	2	P46940	1
+Immunoglobulin subtype 2 [IPR003598]	0.3516209476309119	0.1652957292492933	0.8687112201491596	1.0	0.8819068336197797	5	P35613,Q8WX93,Q13308,P10586	4
+Immunoglobulin subtype [IPR003599]	0.3516209476309119	0.1652957292492933	0.8687112201491596	1.0	0.8819068336197797	5	P35613,Q8WX93,Q13308,P10586	4
+Nuclear transport factor 2 domain [IPR002075]	0.3436609686609663	0.1517668751825407	0.8793708092144155	1.0	0.8904739759974257	4	Q9UN86,Q13283,Q9UBU9	3
+Nuclear transport factor 2, eukaryote [IPR018222]	0.3436609686609663	0.1517668751825407	0.8793708092144155	1.0	0.8904739759974257	4	Q9UN86,Q13283,Q9UBU9	3
+TRIAD supradomain [IPR044066]	0.3387076762528525	0.1474420671700871	0.8827831035331037	1.0	0.8928020794874517	3	O95376	1
+IBR domain [IPR002867]	0.3387076762528525	0.1474420671700871	0.8827831035331037	1.0	0.8928020794874517	3	O95376	1
+Dynamin, N-terminal [IPR045063]	0.3467623642240403	0.1334669889627206	0.8938240696579687	1.0	0.902314524786875	7	O00429,O60313	2
+Dynamin-type guanine nucleotide-binding (G) domain [IPR030381]	0.3467623642240403	0.1334669889627206	0.8938240696579687	1.0	0.902314524786875	7	O00429,O60313	2
+Serine-threonine/tyrosine-protein kinase, catalytic domain [IPR001245]	0.3319088319088322	0.1198518275280168	0.904600525370096	1.0	0.9118009484878304	4	P08069,P41240,Q13308	3
+Sirtuin family, catalytic core domain [IPR026590]	0.3227758007117477	0.1151399233203666	0.9083342160816752	1.0	0.9151809564038988	2	Q8IXJ6	1
+La-type HTH domain [IPR006630]	0.3327161050928851	0.1128395820067315	0.9101577368255158	1.0	0.916634372039427	5	Q71RC2	1
+ATP-grasp fold, succinyl-CoA synthetase-type [IPR013650]	0.3156583629893312	0.0980018935642423	0.9219307897609116	1.0	0.9281027113660056	2	Q96I99	1
+Disulphide isomerase [IPR005788]	0.320270751692191	0.0821503003037964	0.93452719440402	1.0	0.9399968351739434	5	P07237,Q8NBS9,P30101,P13667	4
+Glutathione S-transferase, C-terminal-like [IPR010987]	0.3220328981148209	0.0396524458804053	0.9683702145231488	1.0	0.9736308968419122	11	Q8TB36,Q9H7Z7	2
+SPRY-associated [IPR006574]	0.2938034188034187	0.0353827556423033	0.9717745351057748	1.0	0.9762378001939432	4	P19474,O15344,Q14258	3
+Butyrophylin-like, SPRY domain [IPR003879]	0.2938034188034187	0.0353827556423033	0.9717745351057748	1.0	0.9762378001939432	4	P19474,O15344,Q14258	3
+OBG-type guanine nucleotide-binding (G) domain [IPR031167]	0.2853580334877041	0.0129613651092361	0.989658616446766	1.0	0.9933744810892444	5	P55039,A4D1E9,Q9Y295,Q9NTK5	4

interpro_family/advanced/idx2term.json

@@ -0,0 +1 @@
+{}

interpro_family/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Mitochondrial carrier protein [IPR002067]", "1": "14-3-3 protein [IPR000308]"}

interpro_family/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:ad4988b029a59703cce86a8f0eaa6b88ecce46c302b45e542c025e9b41e37397
+size 499928

interpro_family/df_merge.tsv

@@ -0,0 +1,5 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+Major facilitator superfamily [IPR011701]	4	6	2.442214805354076	0.0145974581558763	1.900485436893204	4.145631067961165	1.0239318262629833	0.2378354197978781	1.3191273068698348	1.552684909115802	1.329586452483978	0.2573287434106264	0.0397170539104867	1.0	0.2052107238795277	0.112413166150522	0.0052134507581354
+Proteasome B-type subunit [IPR023333]	3	7	2.1374938772718277	0.032557843183733	3.699029126213592	6.970873786407767	1.6670727234653664	0.1509307531330224	1.4503762582219135	0.1681602725795027	0.9611878160538336	0.233503072382129	0.0058945182768218	0.04159641685533	0.003087611696091	0.0010341818226167	0.0005688349419973
+Transmembrane emp24 domain-containing protein [IPR015720]	4	6	2.078052773310134	0.0377044987623718	2.6432038834951457	5.099514563106796	0.3626508447128717	0.2724944971681708	1.287119696753696	0.8431907483703972	1.4713835809049645	0.2794327521776852	1.0	1.0	1.0	1.0	1.3106068439724131e-05
+Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase [IPR001930]	4	6	2.0719030355602435	0.0382744848323288	2.121359223300971	5.466019417475728	1.4317001483019938	0.1783942022754649	1.021530403905949	0.5881604361499402	0.986353205880356	0.2226891741813114	0.004624601375411	0.0005968088999726	0.0024164244761899	0.0146338936924203	0.0003286021100258