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d3b81dc verified
Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
Deubiquitination 0.5209315055398197 3.381725302908378 0.0007203213628566 0.6279165123731527 0.0961689798948085 82 Q96FW1,P21796,P45880,P49721,Q9UPU5,Q8TEY7,P25788,P28072,P49720,P28074,Q92783,Q99436,Q9NXR7,Q15750,Q96K76,O75832,P20618,Q8NB78,O14964,P28070,P60900 21
Ub specific processing proteases 0.5410380990923922 3.233232801832424 0.0012239777492784 0.8136867762125415 0.0961689798948085 69 Q96FW1,P25788,Q8TEY7,P28074,Q99436,O75832,P20618,O14964,P21796,P28072,P28070,P45880,P49721,Q15750,Q96K76,Q9UPU5,P60900,P49720 18
Regulation of mrna stability by proteins that bind au rich elements 0.5514143605079885 3.1980581462522326 0.0013835637985957 0.8503661424966233 0.0961689798948085 61 Q01105,Q5RKV6,Q96B26,O00231,P49721,P39687,Q16539,P11940,P25788,Q92973,P28072,Q92945,P49720,P61289,P28074,Q99436,Q14103,O75832,P20618,P04792,P28070,Q9UL46,P60900 23
Dna replication pre initiation 0.5452478166365695 3.111865444543616 0.0018590921409067 0.9221559902237964 0.0961689798948085 59 P25788,P28074,Q99436,P20618,P52294,P28072,P28070,Q9Y619,P49721,O60684,P60900,Q9NR33,P49720 13
Mapk family signaling cascades 0.5058079675525607 3.1096458730819467 0.0018731176740571 0.923642371505163 0.0961689798948085 79 P30086,P30154,O75832,P25788,P28074,P20618,P49356,O60725,Q99436,O43924,P28072,P28070,Q14168,P49721,P60900,P49720,Q06124 17
Regulation of pten stability and activity 0.6159918874575143 3.096925986539343 0.0019553868877837 0.9318072606742004 0.0961689798948085 39 P25788,P28074,Q99436,P20618,P31751,P28072,P28070,P49721,P60900,P49720 10
Auf1 hnrnp d0 binds and destabilizes mrna 0.6032926777265492 3.020514737302009 0.0025234542745842 0.9687755848411 0.0961689798948085 40 Q14103,P11940,P25788,P28074,Q99436,O75832,P20618,P28072,P04792,P28070,P49721,Q9UL46,P60900,P49720 14
The role of gtse1 in g2 m progression after g2 checkpoint 0.5785121435547068 2.993129904874263 0.0027613218764901 0.9774895119757284 0.0961689798948085 46 P25788,P28074,Q99436,P68371,P20618,P28072,P28070,P49721,Q9BVA1,P60900,P49720 11
Regulation of hmox1 expression and activity 0.5855138921250501 2.9569190269667223 0.0031072970655019 0.9860161034688728 0.0961689798948085 43 Q8TCT9,P25788,P28074,Q99436,P20618,P28072,P09601,P28070,P49721,P60900,P49720 11
Degradation of axin 0.6089971118100113 2.955306668086396 0.0031235839708279 0.9863260720325434 0.0961689798948085 35 P25788,P28074,Q99436,P20618,P28072,P28070,P49721,P60900,P49720 9
Cross presentation of soluble exogenous antigens endosomes 0.6089971118100113 2.955306668086396 0.0031235839708279 0.9863260720325434 0.0961689798948085 35 P25788,P28074,Q99436,P20618,P28072,P28070,P49721,P60900,P49720 9
Cellular response to hypoxia 0.5996004331247636 2.9427608307431834 0.0032529962538068 0.9885571006223922 0.0961689798948085 38 Q15369,P25788,P28074,Q99436,P20618,P28072,P28070,P49721,P60900,P49720 10
Sphingolipid metabolism 0.691574946146347 2.93124982763698 0.0033760116163761 0.9903396387340996 0.0961689798948085 22 P16278,P10619,P07602,P06280,O15270,Q06136,P06865,P04062,Q96G23 9
Regulation of runx3 expression and activity 0.6055284520122639 2.9283475975263404 0.0034076884554383 0.990751859457934 0.0961689798948085 35 P25788,P28074,Q99436,P20618,P28072,P28070,P49721,P60900,P49720 9
Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1 0.5709486996402422 2.9275590274989263 0.0034163420497053 0.9908613823807494 0.0961689798948085 46 Q9UJX4,O75832,P25788,P28074,Q99436,Q96DE5,P20618,Q9UJX6,P60900,P28072,P28070,O00231,P49721,Q9UL46,P49720,Q13042,Q9UJX3,Q9UJX2 18
Switching of origins to a post replicative state 0.5269473210452563 2.9206106202513338 0.0034934615018769 0.9917819379803644 0.0961689798948085 58 Q9UBD5,O00231,P49721,Q9UJX2,P25788,P28072,Q13042,P49720,P28074,Q99436,Q96DE5,Q9Y619,Q9UJX3,Q9UJX4,O75832,P20618,Q9UJX6,P28070,Q9UL46,P60900 20
Fceri mediated nf kb activation 0.5963909333200724 2.9170820506984243 0.0035332281440842 0.9922197986308848 0.0961689798948085 38 P25788,P28074,Q99436,P20618,P28072,P28070,P49721,Q15750,P60900,P49720 10
Mitotic g1 phase and g1 s transition 0.5075898817709309 2.900635421390038 0.0037240688339983 0.9940177590904724 0.0961689798948085 70 Q9UBD5,P49721,Q9NR33,P25788,P28072,P49720,P31350,P30154,P28074,Q99436,Q9Y619,O75832,P20618,P31751,P30153,P28070,Q9UL46,P00374,P60900 19
Interleukin 1 signaling 0.5811698004282977 2.891976111300989 0.0038282705416468 0.9948174947242424 0.0961689798948085 42 O75832,P25788,P28074,Q99436,P45985,P20618,Q02750,P28072,P28070,P49721,Q15750,Q9UL46,P60900,Q13501,P49720 15
Stabilization of p53 0.5958027047210565 2.8909146979077045 0.0038412236711287 0.9949091313335938 0.0961689798948085 37 P25788,P28074,Q99436,P20618,P28072,P28070,P49721,P60900,P49720 9
Runx1 regulates transcription of genes involved in differentiation of hscs 0.5864662150919633 2.883557120208131 0.0039321132760972 0.995508164666299 0.0961689798948085 40 P25788,P28074,Q99436,P20618,P28072,P28070,P49721,Q03164,P60900,P49720 10
C type lectin receptors clrs 0.5732735323468511 2.8832676684621426 0.0039357285360321 0.995530477176451 0.0961689798948085 44 P25788,P28074,Q99436,O43865,P20618,P28072,P28070,P49721,Q15750,P60900,P49720 11
G1 s dna damage checkpoints 0.5914605501131036 2.8774978538931837 0.0040084263681834 0.995956371365608 0.0961689798948085 38 P25788,P28074,Q99436,P20618,P28072,P28070,P49721,P60900,P49720 9
Signaling by interleukins 0.4503129238327651 2.8761302186284787 0.0040258359051581 0.9960521929749392 0.0961689798948085 99 P52597,P14174,P08670,O14979,O00231,Q13126,P49721,P04083,P62993,P22626,P25788,P11233,P28072,P46109,P49720,Q53EL6,P30154,P28074,Q99436,P45985,P78417,P09601,Q15750,Q13501,Q06124,O75832,Q07820,P20618,P30153,Q02750,P28070,Q9UL46,P60900 33
Degradation of dvl 0.5959435228706187 2.8720293268084576 0.0040784511661695 0.9963282132507504 0.0961689798948085 36 P25788,P28074,Q99436,P20618,P28072,P28070,P49721,P60900,P49720 9
Signaling by the b cell receptor bcr 0.5787496476565552 2.8717235398985466 0.0040823993671923 0.99634813034571 0.0961689798948085 42 P25788,P28074,Q99436,O43865,P20618,P28072,P28070,P49721,P62942,P60900,P49720 11
Cdt1 association with the cdc6 orc origin complex 0.586937244523857 2.8634644274258485 0.004190358630143 0.996852829057275 0.0961689798948085 39 P25788,P28074,Q99436,P20618,P28072,P28070,Q9Y619,P49721,P60900,P49720 10
Clec7a dectin 1 signaling 0.5768557077513065 2.855844649191033 0.0042922509448461 0.9972650525111844 0.0961689798948085 42 P25788,P28074,Q99436,O43865,P20618,P28072,P28070,P49721,Q15750,P60900,P49720 11
Downstream signaling events of b cell receptor bcr 0.582917072861966 2.8544153110353285 0.0043116125587741 0.9973370531955114 0.0961689798948085 40 P25788,P28074,Q99436,P20618,P28072,P28070,P49721,P62942,P60900,P49720 10
Asymmetric localization of pcp proteins 0.5934433742599541 2.8522532149843465 0.0043410505263181 0.9974429124261552 0.0961689798948085 36 P25788,P28074,Q99436,P20618,P28072,P28070,P49721,P60900,P49720 9
Signaling by notch4 0.5789814747112378 2.8470296961259707 0.0044129245628605 0.9976840400916924 0.0961689798948085 41 O75832,P25788,P28074,Q99436,P20618,Q92542,P28072,P28070,O00231,P49721,Q9Y6A5,Q9UL46,P60900,Q06330,P49720 15
Regulation of ras by gaps 0.5880890678396086 2.8293227511934873 0.0046646630718909 0.9983630017446856 0.0961689798948085 37 P25788,P28074,Q99436,P20618,P28072,P28070,P49721,P60900,P49720 9
Mapk6 mapk4 signaling 0.5595064251797558 2.82751452001502 0.0046910887979836 0.9984215588631165 0.0961689798948085 46 O75832,P25788,P61289,P28074,Q99436,P20618,P28072,P04792,P28070,O00231,P49721,Q9UL46,P60900,P49720 14
Metabolism of polyamines 0.5874442220918002 2.8241554811816028 0.0047405382193506 0.9985255697069167 0.0961689798948085 37 P25788,P28074,Q99436,P20618,P28072,P28070,P49721,P60900,P49720 9
Degradation of beta catenin by the destruction complex 0.5608553324223404 2.807065838712381 0.0049995022329814 0.9989682728267544 0.0961689798948085 45 O75832,P25788,P28074,Q99436,P20618,Q13363,P30153,P28072,P28070,P49721,Q9UL46,P60900,P49720,P30154 14
Fc epsilon receptor fceri signaling 0.5566426070651476 2.802314092435147 0.005073744949021 0.999068670714342 0.0961689798948085 46 P25788,P28074,Q99436,O43865,P45985,P20618,P28072,P28070,P49721,Q15750,P60900,P49720 12
Apc c mediated degradation of cell cycle proteins 0.5217623690142827 2.7957119366241345 0.0051785535296671 0.9991940073628888 0.0961689798948085 54 Q9UJX4,O75832,P25788,P28074,Q99436,Q96DE5,P20618,Q9UJX6,P60900,P28072,P28070,O00231,P49721,Q9UL46,P49720,Q13042,Q9UJX3,Q9UJX2 18
Transcriptional regulation by runx3 0.5744665867096019 2.7846686632489175 0.0053582445724988 0.9993709361472772 0.0961689798948085 40 O75832,P25788,P28074,Q99436,P20618,P28072,P28070,O00231,P49721,Q9UL46,P60900,Q06330,P49720 13
Disorders of transmembrane transporters 0.4889746751193191 2.7837608376616783 0.0053732638608705 0.99938383478308 0.0961689798948085 74 P55735,Q99567,O75477,P49721,P53985,P57740,P25788,P28072,P49720,Q9BW27,P28074,Q99436,Q9BTX1,O75832,P20618,Q8NFH4,P28070,P35613,Q9UL46,P60900,Q12769 21
Abc family proteins mediated transport 0.5467592313038362 2.78298211893251 0.00538617745208 0.9993947135244524 0.0961689798948085 48 O75832,P25788,P28074,Q99436,P20618,P28072,O75477,O00231,P28070,P49721,P08183,Q9UL46,P40855,P60900,P49720 15
Hedgehog ligand biogenesis 0.5796632364225652 2.7821032076041843 0.0054007862076073 0.9994067891161642 0.0961689798948085 38 P25788,P28074,Q99436,P20618,P28072,P28070,P49721,P60900,P49720 9
Degradation of gli1 by the proteasome 0.5761221197606666 2.775070187821133 0.0055189795677921 0.999496039231318 0.0961689798948085 39 P25788,P28074,Q99436,P20618,P28072,P28070,P49721,P60900,P49720 9
Transcriptional regulation by runx1 0.5035188662474233 2.754175255943047 0.0058840250696226 0.999695465597099 0.0968611112726662 64 O00231,P49721,Q03164,Q07157,P25788,P28072,P49720,Q99873,P61289,P28074,Q99436,Q8IXK0,Q969G3,Q96ST3,Q9HCE1,P17931,Q06124,O75832,P20618,Q99496,P28070,Q9UL46,P60900 23
Transcriptional regulation by runx2 0.5430678204814232 2.7495762132316135 0.0059672384257458 0.9997285074271056 0.0968611112726662 48 P25788,P28074,Q99436,P20618,P31751,P28072,P28070,P49721,P60900,P49720,Q96PK6 11
Hedgehog on state 0.5728314629288387 2.748011576390281 0.0059957892099589 0.9997389981771556 0.0968611112726662 39 P25788,P28074,Q99436,P20618,P28072,P28070,P49721,P60900,P49720 9
Tcf dependent signaling in response to wnt 0.5103018255927542 2.737545631686082 0.0061899531949316 0.9998003628727138 0.0968611112726662 56 O75832,P25788,P28074,Q99436,P20618,P31751,P40818,Q13363,P30153,P28072,P28070,P49721,Q9UL46,P60900,P49720,P30154 16
Negative regulation of notch4 signaling 0.5740458070891332 2.736340733798666 0.0062126660291506 0.9998065256597086 0.0968611112726662 38 O75832,P25788,P28074,Q99436,P20618,P28072,P28070,O00231,P49721,Q9Y6A5,Q9UL46,P60900,P49720 13
Cyclin a cdk2 associated events at s phase entry 0.5664132556984129 2.717724343464727 0.0065732576347998 0.9998824069357308 0.0977514169325784 40 P25788,P28074,Q99436,P20618,P31751,P28072,P28070,P49721,P60900,P49720 10
Hedgehog off state 0.5454907687960171 2.7035628071569966 0.0068600482109302 0.9999208699528184 0.0977514169325784 46 P25788,P28074,Q99436,P68371,P20618,P28072,P28070,P49721,Q9BVA1,P60900,P49720 11
Defective cftr causes cystic fibrosis 0.5640140041365101 2.697689936450463 0.0069822440666127 0.9999331620177296 0.0977514169325784 40 O75832,P25788,P28074,Q99436,P20618,P28072,O75477,P28070,P49721,Q9UL46,P60900,P49720 12
Abc transporter disorders 0.5640140041365101 2.697689936450463 0.0069822440666127 0.9999331620177296 0.0977514169325784 40 O75832,P25788,P28074,Q99436,P20618,P28072,O75477,P28070,P49721,Q9UL46,P60900,P49720 12
Tnfr2 non canonical nf kb pathway 0.564875582206775 2.682274087800744 0.0073123521658715 0.9999576443075764 0.1003254717157578 39 P25788,P28074,Q99436,P20618,P28072,P28070,P49721,P60900,P49720 9
Dectin 1 mediated noncanonical nf kb signaling 0.564875582206775 2.682274087800744 0.0073123521658715 0.9999576443075764 0.1003254717157578 39 P25788,P28074,Q99436,P20618,P28072,P28070,P49721,P60900,P49720 9
Cytokine signaling in immune system 0.4567495458017842 2.6762379733942008 0.0074453758730546 0.9999647580342008 0.1005405027687984 165 Q15369,P55735,P15260,Q99567,P52597,P14174,P08670,O14979,O00231,Q13126,P49721,P04083,P62993,Q14258,P57740,P22626,P04439,O00505,P25788,P11233,O00629,P52294,P01889,P28072,P46109,P49720,Q53EL6,P30154,P10321,O15344,Q9BW27,P28074,Q99436,P45985,P78417,P09601,Q15750,Q13501,Q06124,O75832,Q07820,P20618,P31751,Q9BTX1,P30153,Q8NFH4,Q02750,P28070,P19474,Q9UL46,P60900,Q12769 52
Separation of sister chromatids 0.4357826662169125 2.6749255147279514 0.0074745854828115 0.9999661526473512 0.1005405027687984 100 P55735,P68371,Q92674,O60216,O00231,P49721,Q8WYP5,Q99661,Q9BUF5,Q9H1A4,Q9HBM1,Q9UJX2,P57740,O60566,P25788,P28072,Q13042,Q9Y266,P49720,P30154,Q8NI77,Q9BW27,P61289,P28074,Q99436,Q96DE5,Q9UJX3,Q7L7X3,Q9UJX4,O75832,P20618,Q9UJX6,P30153,Q8NFH4,P28070,Q8NBT2,Q9UL46,Q15691,Q9BVA1,P60900,Q12769 41
Glycosphingolipid metabolism 0.7708671309117558 2.6575193115681803 0.0078718080350319 0.9999804562157912 0.1018879304156966 13 P16278,P10619,P07602,P06280,P06865,P04062 6
Transport of small molecules 0.4477258180083505 2.6308797810770277 0.008516415588635 0.9999919879317202 0.1070433411252286 137 Q70HW3,P21796,Q9C0H2,P45880,P49721,P36543,P53985,P30519,Q8WTV0,Q9Y487,Q93050,P28072,Q9UBX3,P28074,Q99436,P09601,O15118,P08183,Q9HD20,P20618,P28070,P60900 22
Glycerophospholipid biosynthesis 0.5944934698604409 2.626434619566211 0.0086284566761976 0.9999931386829336 0.1070433411252286 27 Q99829,Q8N2A8,Q8NF37,Q8IV08,Q9BZF1,Q9NPH0,Q8NCC3,Q99943,P35790 9
Uch proteinases 0.5467325974679841 2.6259068794469846 0.0086418455798344 0.9999932646496084 0.1070433411252286 43 P25788,P28074,Q99436,P20618,Q8NB78,P28072,P28070,P49721,P60900,P49720 10
Regulation of runx2 expression and activity 0.5525993965970147 2.6251841319861557 0.0086602120006562 0.9999934336954076 0.1070433411252286 41 P25788,P28074,Q99436,P20618,P28072,P28070,P49721,P60900,P49720 9
Interferon signaling 0.4904106769866896 2.5799065859040056 0.009882704435272 0.999998791964842 0.1137433628890103 61 O15344,P55735,O00505,P10321,Q9BW27,P15260,Q9BTX1,Q99567,O00629,P01889,P52294,Q8NFH4,P19474,P57740,Q12769,Q06124,P04439 17
Pten regulation 0.4922947756390756 2.579692753877915 0.0098888253788971 0.999998802167804 0.1137433628890103 59 O00231,P49721,Q15022,P25788,P28072,P49720,P61289,P28074,Q99436,Q8IXK0,Q9HCE1,O75832,Q92769,P31751,P20618,P28070,O95983,Q9UL46,P60900,P42345 20
Scf skp2 mediated degradation of p27 p21 0.5523208888671488 2.577617713119907 0.0099483990865023 0.9999988970819144 0.1137433628890103 39 P25788,P28074,Q99436,P20618,P28072,P28070,P49721,P60900,P49720 9
Orc1 removal from chromatin 0.5197106376392627 2.570456112748099 0.0101564694701707 0.9999991733814448 0.114310754691944 49 P25788,P28074,Q99436,P20618,P28072,P28070,Q9Y619,P49721,P60900,P49720 10
Iron uptake and transport 0.6901090302257988 2.570176919387007 0.0101646589449104 0.9999991827115812 0.114310754691944 18 Q9Y487,Q93050,P09601,P36543,P30519 5
Tcr signaling 0.5457410843877281 2.566674394834253 0.0102678978344183 0.999999291686856 0.1145329742180653 41 P25788,P28074,Q99436,P20618,P28072,P28070,P49721,P60900,P49720 9
Signaling by hedgehog 0.5099530437165619 2.5530645350141823 0.0106779709441886 0.9999995988596658 0.1162712391700542 51 P25788,P28074,Q99436,P68371,P20618,P28072,P28070,P49721,Q9BVA1,P60900,P49720 11
Intracellular signaling by second messengers 0.4670275046662088 2.5344682560612033 0.011261813015116 0.9999998215345026 0.1178215447486349 74 O00231,P49721,P10644,P62993,Q15022,P25788,P28072,P49720,P30154,P61289,P28074,Q99436,O43865,Q8IXK0,Q9HCE1,Q06124,O75832,Q92769,P31751,P20618,P30153,P28070,O95983,Q9UL46,P60900,P42345 26
Signaling by insulin receptor 0.713376140355682 2.5117920766428417 0.0120119838673327 0.9999999370057964 0.1223021452819988 15 P31751,Q9Y487,Q93050,Q15904,P36543,P62993,P61421,Q06124 8
Cytoprotection by hmox1 0.4820986319800547 2.4829806592422705 0.0130288161354894 0.999999984663124 0.1304783630503031 60 Q8TCT9,P25788,P28074,Q99436,P20618,P28072,P09601,P28070,P49721,Q86X55,P60900,P49720,P30519 13
Interferon gamma signaling 0.7355284989360369 2.474089789207013 0.0133576120864475 0.9999999902903433 0.1328017665406239 13 O15344,P10321,P15260,P01889,P19474,Q14258,Q06124,P04439 8
Ns1 mediated effects on host pathways 0.5508702664298578 2.4613354631318702 0.0138420872338689 0.9999999950506484 0.1338673435138936 34 P55735,O00505,Q9BW27,Q9BTX1,O00629,P52294,Q8NFH4,P57740,Q12769 9
G2 m checkpoints 0.4581645163882647 2.454299556040584 0.0141159336682266 0.999999996618861 0.1344934791167146 75 P25788,P28074,Q99436,P20618,P28072,Q9NXR7,Q9Y619,P28070,P49721,O96028,Q9UQ84,P60900,P49720 13
Mitochondrial protein import 0.556917800030937 2.4277510656700914 0.0151927672454688 0.9999999992451044 0.1427703880875562 31 Q9Y512,Q9NS69,Q99595,O60830,P21796,Q5JRX3 6
Interleukin 1 family signaling 0.5172648298878817 2.4199775544278213 0.0155214651362396 0.999999999522496 0.1448670079382367 45 O75832,P25788,P28074,Q99436,P45985,P20618,P28072,P28070,P49721,Q15750,P60900,P49720,Q06124 13
Mitotic g2 g2 m phases 0.4482779381101531 2.384639334793093 0.0170958726618384 0.9999999999468736 0.1543127453423837 77 O94927,P25788,P20618,P28074,Q99436,P68371,P28072,P28070,P49721,O75935,P07437,Q9BVA1,P60900,P49720,O95684,P30154 16
Antigen processing cross presentation 0.5041537255265276 2.3587355619364248 0.0183373175040815 0.999999999990619 0.1644365987947702 47 P10321,P25788,P28074,Q99436,P20618,P01889,P28072,P28070,P49721,Q9UIQ6,P60900,P49720,P04439 13
Host interactions of hiv factors 0.4056994489681688 2.325364691076751 0.020052467835909 0.9999999999991483 0.1741264928535902 92 Q15369,P55735,Q99567,P49721,P57740,P04439,P25788,P52294,P28072,P49720,Q9BW27,P28074,Q99436,O75832,Q9BTX1,P20618,Q8NFH4,P28070,Q9UL46,P60900,Q12769 21
Signaling by notch 0.4720443035129223 2.2590045313606373 0.0238831030077164 0.999999999999996 0.1927506901563939 53 P67809,O75832,P25788,P61289,P28074,Q99436,Q92542,Q92769,P20618,P28072,P28070,O00231,P49721,Q9Y6A5,Q9UL46,P60900,Q06330,P49720 18
Costimulation by the cd28 family 0.7261125001615742 2.2439851054922717 0.0248333596861112 0.999999999999999 0.1992477747914888 11 P30154,P31751,P30153,P42345,Q06124 5
Transferrin endocytosis and recycling 0.7222023517393802 2.224188112045158 0.0261357905489947 1.0 0.2072734371862472 11 P02786,Q9Y487,Q93050,Q15904,P36543,P21283,P61421 7
Protein localization 0.4480631545679098 2.1689048388507595 0.030089909310963 1.0 0.2318195845832739 65 Q9NS69,Q8TB36,O75874,Q99595,O60830,P21796,Q10713,O14925,O15254,Q9BY49,Q5JRX3,P50402,Q9Y512,P46379,P51648,O43765,Q9NX63,Q13505,Q15067,P09601,O00116,Q8N4H5 22
Dna replication 0.4138708441752179 2.148178386302626 0.0316995870276002 1.0 0.2402863723860083 84 Q9UBD5,O00231,P49721,Q9NR33,Q9UJX2,P25788,P52294,P28072,O60684,Q13042,P49720,P28074,Q99436,Q96DE5,Q9Y619,Q9UJX3,Q9Y2S7,Q9UJX4,O75832,P20618,Q9UJX6,P28070,Q9UL46,P60900 24
Insulin receptor recycling 0.7279777291469963 2.1197948560331703 0.0340233493025687 1.0 0.2496258569151036 10 Q9Y487,Q93050,Q15904,P36543,P61421 5
Cellular response to chemical stress 0.4356665411252066 2.1135320830688684 0.034555251985026 1.0 0.2500177486548909 71 Q8TCT9,P25788,P28074,Q99436,P20618,P28072,P09601,P28070,P49721,Q86X55,P60900,P49720,P30519 13
Mitophagy 0.6846692874091048 2.1130934440265965 0.0345927707086326 1.0 0.2500177486548909 12 P21796,Q9NS69 2
Pyruvate metabolism 0.6685226764053724 2.0272529752161534 0.0426365479707451 1.0 0.2730652089863393 12 P21796 1
Glycosaminoglycan metabolism 0.651844108827758 2.0236730777645664 0.0430038004266746 1.0 0.2730652089863393 13 P16278,Q7LGA3,Q8TB61,O43505,P54802,P08236,P06865 7
Apoptosis 0.4053813212507253 2.009143514344131 0.0445219160393517 1.0 0.2751534630900477 83 P30419,O75832,P25788,P28074,P20618,Q99436,Q9NR28,P31751,P52294,P08670,P28072,P28070,P49721,O60443,P60900,P49720 16
Diseases of signal transduction by growth factor receptors and second messengers 0.400199709635878 2.0048328185290094 0.0449809227608668 1.0 0.2767436144749297 127 P30086,Q92734,Q13363,O00231,P49721,P10644,P62993,O95684,Q6UN15,Q16543,Q14789,P25788,P28072,P62942,Q6RW13,P51114,Q06330,P49720,P30154,P61289,P28074,Q99436,Q96PU8,Q92542,O15514,Q13501,Q9NRY5,Q06124,O43252,O75832,P20618,P31751,Q92769,P30153,Q02750,P28070,Q9UL46,P60900,P42345 39
S phase 0.3898286955691213 1.9915827375325263 0.0464168589648763 1.0 0.2843032611598676 89 Q9UBD5,O60216,O00231,P49721,Q9NR33,Q9UJX2,P25788,P28072,Q13042,P49720,P28074,Q99436,Q96DE5,Q9Y619,Q9UJX3,Q9Y2S7,Q9UJX4,O75832,P20618,P31751,Q9UJX6,P28070,Q9UL46,P60900 24
Selective autophagy 0.5062639775120693 1.9595222161398893 0.0500516607302887 1.0 0.2972765303980788 27 Q9BVA1,P21796,Q8N4H5,Q9NS69 4
Ros and rns production in phagocytes 0.7168371778437785 1.9462469249001848 0.0516250856825466 1.0 0.3026906733181794 9 Q9Y487,Q93050,P61421,P36543 4
Synthesis of pc 0.7934474401079648 1.9317822361759596 0.053386389523182 1.0 0.3091350951682547 6 P35790 1
Conversion from apc c cdc20 to apc c cdh1 in late anaphase 0.7128258367980095 1.9269846379755555 0.0539815444372731 1.0 0.3098856860583209 9 Q9UJX4,Q96DE5,Q9UJX6,Q13042,Q9UJX3,Q9H1A4,Q9UJX2 7
Negative regulation of met activity 0.7307466111707108 1.9156764562243376 0.0554062910250994 1.0 0.3141759720390221 8 O14964,P40818,Q92783 3
Phospholipid metabolism 0.47391630145966 1.8983225280380145 0.0576536080911751 1.0 0.3215477654515947 39 Q99829,Q8N2A8,Q9Y217,Q8NF37,Q8IV08,Q9BZF1,Q9NPH0,Q8NCC3,Q99943,P42356,P35790 11
Interferon alpha beta signaling 0.6821299130794002 1.8920023061156963 0.058490673545126 1.0 0.3226776441311579 10 P01889,Q06124,P04439 3
Pink1 prkn mediated mitophagy 0.7038250950141565 1.8836237054869347 0.0596158929974275 1.0 0.3253923138438225 9 P21796,Q9NS69 2
Synthesis of dna 0.402525817543701 1.870508710094292 0.0614132085992444 1.0 0.3304271458751507 79 Q9UBD5,O00231,P49721,Q9NR33,Q9UJX2,P25788,P28072,Q13042,P49720,P28074,Q99436,Q96DE5,Q9Y619,Q9UJX3,Q9Y2S7,Q9UJX4,O75832,P20618,Q9UJX6,P28070,Q9UL46,P60900 22
Apc cdc20 mediated degradation of nek2a 0.6380764019525633 1.863273594060048 0.0624237832993586 1.0 0.3332507030611673 12 Q9UJX4,O60566,Q96DE5,Q9UJX6,Q13042,Q9UJX3,Q9H1A4,Q9UJX2 8
Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components 0.6380764019525633 1.863273594060048 0.0624237832993586 1.0 0.3332507030611673 12 Q9UJX4,O60566,Q96DE5,Q9UJX6,Q13042,Q9UJX3,Q9H1A4,Q9UJX2 8
Cholesterol biosynthesis 0.6068204900698032 1.861220327616746 0.0627130688892045 1.0 0.3334974051007313 14 Q16850,Q15392,P48449,Q9BWD1,Q15800 5
Pcp ce pathway 0.4500030650514732 1.8425561315844432 0.0653938439112691 1.0 0.338310850228225 47 O75832,P25788,P28074,Q99436,P20618,P28072,P28070,P49721,P60900,P49720 10
Ras processing 0.7705575108245488 1.8340866878521855 0.0666411271633284 1.0 0.342440548569613 6 P49356,O43924 2
Apc c cdc20 mediated degradation of cyclin b 0.6435872414347884 1.8168022421824923 0.0692473993877651 1.0 0.3519836166753276 11 Q9UJX4,Q96DE5,Q9UJX6,Q13042,Q9UJX3,Q9H1A4,Q9UJX2 7
Keratan sulfate keratin metabolism 0.8336429324226065 1.8166683360789555 0.069267912902579 1.0 0.3519836166753276 5 P06865,O43505 2
Beta catenin independent wnt signaling 0.4351825417901733 1.8115426814610016 0.0700568884140573 1.0 0.354679154627626 51 O75832,P25788,P28074,Q99436,P20618,P28072,P28070,P49721,P60900,P49720 10
Signaling by braf and raf1 fusions 0.5334470020016228 1.791270391837799 0.0732499150153576 1.0 0.3654504850948023 21 P30086,Q96PU8,Q02750,Q6RW13,P51114 5
Programmed cell death 0.3681461700422497 1.7705179432638558 0.0766408979782864 1.0 0.3782421295906798 95 Q16543,P30419,O75832,P25788,P28074,P20618,Q99436,Q9NR28,P31751,P52294,P08670,P28072,P28070,P49721,O60443,P60900,P49720 17
Gpcr ligand binding 0.6983704373698761 1.7642300419302397 0.0776932567508363 1.0 0.3815736987308942 8 P04083,P07602,P42892 3
Cell cycle checkpoints 0.3836423093626808 1.7515694800158994 0.0798478643600797 1.0 0.3898621704698555 129 P55735,Q9Y3B8,Q9UBD5,Q92674,O00231,P49721,O96028,Q8WYP5,Q99661,P57740,Q9H1A4,Q9UJX2,Q9HBM1,P25788,P28072,Q12888,Q13042,P49720,P30154,Q8NI77,Q9BW27,P61289,P28074,Q99436,Q96DE5,Q9NXR7,Q9Y619,Q9UJX3,Q7L7X3,Q9UJX4,O75832,P20618,Q9UJX6,P30153,Q8NFH4,P28070,Q8NBT2,Q9UL46,Q15691,Q9UQ84,P60900,Q12769 42
Assembly and cell surface presentation of nmda receptors 0.7047446503546072 1.7091023403859535 0.0874319941509194 1.0 0.4174879366317177 7 P68371,Q9BVA1,O14936 3
Platelet activation signaling and aggregation 0.4431267819585968 1.7056692368708124 0.088069680418148 1.0 0.4174879366317177 44 O43852,Q8NBX0,Q9NTK5,P07602,Q06481,Q13685,Q9NUQ9,Q06124 8
Inlb mediated entry of listeria monocytogenes into host cell 0.7399638839042053 1.7020832823222696 0.0887397573252095 1.0 0.4174879366317177 6 O14964,Q92783 2
Cd28 co stimulation 0.7398246094325819 1.7014787877757584 0.0888531177087912 1.0 0.4174879366317177 6 P42345,P31751 2
Antigen presentation folding assembly and peptide loading of class i mhc 0.5777143608048422 1.6911601439502555 0.0908062208276121 1.0 0.4252086517934603 14 P10321,P55735,P01889,Q6P179,P04439 5
Platelet homeostasis 0.6633664146992297 1.686407047202479 0.0917174250134136 1.0 0.4265637529437406 9 P30153,Q06124,P30154 3
Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways 0.6985399681773153 1.6806745278754118 0.0928261508649899 1.0 0.4284560038233091 7 Q13685,Q15750,P09601 3
Listeria monocytogenes entry into host cells 0.6804826698608528 1.6796135739487374 0.0930325249420702 1.0 0.4284560038233091 8 O14964,Q92783 2
Peptide ligand binding receptors 0.7343896424733571 1.677865139083123 0.0933734294046424 1.0 0.4284560038233091 6 P04083,P07602,P42892 3
Class a 1 rhodopsin like receptors 0.7343896424733571 1.677865139083123 0.0933734294046424 1.0 0.4284560038233091 6 P04083,P07602,P42892 3
Regulation of ifng signaling 0.902819919794566 1.6718535437620805 0.0945532054360076 1.0 0.4290806213663314 4 Q06124 1
Phosphorylation of the apc c 0.6029475610067107 1.670803402664179 0.0947605162346927 1.0 0.4290806213663314 12 Q9UJX4,Q96DE5,Q9UJX6,Q13042,Q9UJX3,Q9H1A4,Q9UJX2 7
Gene and protein expression by jak stat signaling after interleukin 12 stimulation 0.4712620303070703 1.6662754101432893 0.0956585720883296 1.0 0.429891147058328 25 P11233,P52597,P14174,P78417,O14979,Q13126,Q53EL6,P22626 8
Visual phototransduction 0.7314984271455801 1.6652844744359152 0.0958560145024232 1.0 0.429891147058328 6 P49356,P30419,P29375 3
Release of apoptotic factors from the mitochondria 0.9291814946619256 1.6651666506711278 0.09587951239056 1.0 0.429891147058328 2 O60443 1
Mucopolysaccharidoses 0.8979781678102209 1.653508377804568 0.0982274424851983 1.0 0.430830707348381 4 P54802,P08236 2
Diseases of carbohydrate metabolism 0.6552550847512313 1.6464362611436691 0.099673972695919 1.0 0.4338724478810552 9 P16278,P10253,P54802,P08236 4
Bmal1 clock npas2 activates circadian gene expression 0.9238434163701124 1.6432630459826076 0.1003285205975266 1.0 0.434229432996235 2 P43490 1
Response to elevated platelet cytosolic ca2 0.4641847211403558 1.635961652485024 0.1018476133597456 1.0 0.4380405189014767 28 O43852,Q8NBX0,Q9NTK5,P07602,Q06481,Q9NUQ9 6
Innate immune system 0.3812180347978753 1.623905563808245 0.1043959649468244 1.0 0.44158042161198 258 O75874,P68371,P14174,Q9BTY2,P42785,P49721,P08236,Q9UQB8,P36543,O00264,P30519,P07858,P04439,P16278,P09960,O00584,P25788,Q8NF37,Q9Y487,P01889,Q93050,P28072,P06280,O15260,P10253,O95721,Q13685,P49720,P30154,P10321,P10619,P28074,Q99436,P45985,Q8IV08,P11717,O43865,Q92820,P09601,Q15750,O60443,Q06124,O75832,P07602,P20618,Q02750,P28070,P19474,P07437,P60900,Q9H7Z7,P17900 52
Cell surface interactions at the vascular wall 0.5661554693693516 1.6229421302185103 0.1046017762564821 1.0 0.44158042161198 14 Q01650,P14174,P35613,Q9Y624,P53985,Q06124,Q92896 7
Transport of inorganic cations anions and amino acids oligopeptides 0.6284202921501518 1.618409068597253 0.1055744689375914 1.0 0.4438094273518739 10 Q70HW3,Q9UBX3 2
Endosomal vacuolar pathway 0.8871082621082592 1.6122517880371765 0.1069071599367297 1.0 0.4460022116880551 4 Q9UIQ6,P01889,P04439 3
Collagen formation 0.602287167611513 1.596037404877927 0.110480442417955 1.0 0.4551926936859891 11 Q32P28,P13674,P07858 3
Interleukin 3 interleukin 5 and gm csf signaling 0.7756694881318575 1.581543378210779 0.1137538487866263 1.0 0.4631813607077838 5 P46109,Q06124 2
Gamma carboxylation hypusine formation and arylsulfatase activation 0.6598988414773657 1.581473708957083 0.1137697657132092 1.0 0.4631813607077838 8 O60725,Q9HA64,P38435,Q9BU89 4
Ion channel transport 0.4576420224157768 1.5730898632620798 0.1156980117703068 1.0 0.4696380832806537 27 Q9HD20,Q9Y487,Q93050,Q9C0H2,P36543 5
Metalloprotease dubs 0.8744629160844997 1.5641415768994953 0.1177843237989124 1.0 0.4737912825100466 4 Q92783 1
Oncogenic mapk signaling 0.4687460226150669 1.5589686640454128 0.1190037970432997 1.0 0.4737912825100466 24 P30086,Q96PU8,Q02750,Q6RW13,P51114 5
Synthesis of pa 0.652942900884403 1.5481351957023497 0.1215897498309435 1.0 0.4797167989128118 8 Q9NPH0,Q8N2A8,Q8NF37 3
Ctla4 inhibitory signaling 0.7659200613380925 1.5416083771639 0.1231687886316077 1.0 0.4814460911754012 5 P30154,Q06124,P31751 3
Heme degradation 0.765163083364781 1.5385035743289708 0.1239255352560217 1.0 0.4816595874539996 5 P30519 1
Mitotic metaphase and anaphase 0.3712149067353802 1.5326854177838527 0.1253533838067861 1.0 0.4858328886522899 135 P55735,P68371,Q92674,O60216,O00231,P49721,Q8WYP5,Q99661,Q9BUF5,Q9H1A4,Q9UJX2,Q9HBM1,P57740,P50402,O60566,P25788,Q92973,P28072,Q13042,Q9UN37,Q9Y266,P49720,P30154,Q8NI77,Q9BW27,P61289,P28074,Q99436,Q96DE5,Q9UJX3,P42166,O43633,Q7L7X3,Q14739,O75832,Q9UJX4,P20618,Q9BTX1,Q8IXJ6,Q9UJX6,Q86XL3,Q8NFH4,P30153,P28070,Q8NBT2,Q9UL46,Q15691,Q9BVA1,P60900,Q12769 50
Signalling to erks 0.6661075003355246 1.5309818360482117 0.1257738818798275 1.0 0.4860894815186573 7 P62993,P46109,Q02750,P11233 4
Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps 0.5292964458731155 1.5152853670768434 0.1297001523830934 1.0 0.4984554875899276 17 O76024,O43852,Q02818,Q07065,Q15293,Q9BTY2,Q06481,O43493,Q8NBJ4,P14625 10
Tgf beta receptor signaling in emt epithelial to mesenchymal transition 0.8907473309608535 1.5072085573685745 0.1317572074958708 1.0 0.5028046380031189 2 Q9Y624 1
Interleukin 12 signaling 0.4491971038193097 1.5048086572237298 0.1323732773755859 1.0 0.5030917910230024 27 P11233,P52597,P14174,P78417,O14979,Q13126,Q53EL6,P22626 8
Antiviral mechanism by ifn stimulated genes 0.4151139675121569 1.4983499586265732 0.1340423505069423 1.0 0.5066283881419419 47 P55735,O00505,Q9BW27,Q9BTX1,Q99567,O00629,P52294,Q8NFH4,P57740,Q12769 10
Slc mediated transmembrane transport 0.4900592404112118 1.4860858675218462 0.1372564099275526 1.0 0.5159336833441156 21 Q01650,Q8NEW0,Q8TB61,Q70HW3,P35613,P53985,Q9UBX3 7
Hs gag degradation 0.9437522249910996 1.467884901752769 0.1421354900315439 1.0 0.5284820930170142 3 P54802,P08236 2
Diseases of glycosylation 0.5283118327219007 1.465959636449853 0.1426592834727231 1.0 0.5287860851225392 16 P10619,P06865,O43505 3
Jnk c jun kinases phosphorylation and activation mediated by activated human tak1 0.8797153024911039 1.461803733630811 0.1437950006954411 1.0 0.5289188765526682 2 P45985 1
Phase i functionalization of compounds 0.5365570480991623 1.4467210036501128 0.1479750794022367 1.0 0.5413914905063169 14 P07099,Q16850 2
Platelet sensitization by ldl 0.7382452085778568 1.4277534949143105 0.153362822703339 1.0 0.5525500993814724 5 P30154,P30153,Q06124 3
Signaling by gpcr 0.4279491940213777 1.4205244450776868 0.1554550571146125 1.0 0.5525500993814724 34 P07602,P31751,P62136,O43865,P30153,P04083,P10644,P42892,Q9BYT8,P30154 10
Mitochondrial calcium ion transport 0.5318478599196957 1.4185066249127236 0.1560429058863937 1.0 0.5532063743569305 14 P21796 1
Sialic acid metabolism 0.8353142848541184 1.4145674701596858 0.1571953521458171 1.0 0.5534772986633945 4 P10619 1
Metabolism of steroid hormones 0.6410286565451414 1.414110186085124 0.1573295528270581 1.0 0.5534772986633945 7 P30536 1
Metabolism of porphyrins 0.5871467536664944 1.4039214453740447 0.160342242875763 1.0 0.5584013440763866 10 P30519 1
Metabolism of lipids 0.369352617112634 1.4019676713890394 0.1609249007878812 1.0 0.5584013440763866 156 P30536,Q99829,P62136,Q15392,Q14914,P42126,P48449,O15254,Q96N66,P06865,Q15800,Q9BY49,Q96G23,P09960,P16278,Q8N2A8,Q8NF37,Q9BZF1,P06280,Q9NPH0,P51648,O95772,Q709F0,Q9BWD1,P37268,Q9UMR5,P10619,P50897,Q16850,Q8IV08,Q15067,O15270,O43772,O00116,Q8NCC3,P04062,Q86X55,P35790,Q14739,P07602,Q9Y217,Q15165,Q16836,Q06136,Q99943,P42356,P23786,Q9H7Z7,P17900 49
Signaling by type 1 insulin like growth factor 1 receptor igf1r 0.6707909651248145 1.3984258350330745 0.1619852295498556 1.0 0.5584013440763866 6 Q06124,P31751 2
Signaling by receptor tyrosine kinases 0.3478882908559018 1.3924430555222795 0.1637882741411573 1.0 0.5617937803041698 105 P52597,Q9UQB8,P36543,P62993,Q16543,Q16539,P31943,P11233,Q9Y487,Q93050,Q13685,P31483,P46109,P21283,P30154,Q92783,O43865,Q92542,O15514,Q96ST3,Q06124,P35269,Q92769,P31751,O14964,P40818,P30153,Q02750,P04792,Q15904,Q01085,P61421,P42345 33
Heparan sulfate heparin hs gag metabolism 0.7291575401310568 1.3902322533464528 0.1644583623158553 1.0 0.5626854690707069 5 P16278,P54802,P08236 3
Insertion of tail anchored proteins into the endoplasmic reticulum membrane 0.582291717409175 1.378497202136974 0.1680498310944691 1.0 0.5692490416813347 10 O43765,P50402,P46379,P09601 4
Antigen processing ubiquitination proteasome degradation 0.3552607535006801 1.3709053251006442 0.1704044711351777 1.0 0.5738839620482298 84 Q15369,Q9Y3I1,P55786,O00231,P49721,Q9UIQ6,Q9UJX2,Q9UBS8,P25788,P28072,Q92990,Q13042,P49720,P52888,P28074,Q99436,Q9UJX3,Q9UJX4,O75832,P20618,Q9UJX6,P28070,P19474,Q9UL46,P60900 25
Immunoregulatory interactions between a lymphoid and a non lymphoid cell 0.7242840003965455 1.3700882006753303 0.1706593706382491 1.0 0.5738839620482298 5 P10321,P01889,P04439 3
Ksrp khsrp binds and destabilizes mrna 0.5329060295917905 1.347412080257936 0.177847552083016 1.0 0.5951386377021903 13 Q92945,Q16539,Q5RKV6,Q96B26 4
Signaling by egfr 0.5445422033326258 1.3442448006921042 0.1788692388240436 1.0 0.5964014032459863 12 Q06124,Q92783,Q13685 3
Mrna decay by 3 to 5 exoribonuclease 0.5120881089651984 1.3292134067967836 0.1837775731677862 1.0 0.6061125730437563 15 Q96C86,Q6PGP7,Q969T7,Q96B26 4
Sphingolipid de novo biosynthesis 0.5898556346055215 1.3197786005996792 0.1869089483106447 1.0 0.6120900144146021 9 P51648,Q96G23,O15270,Q06136 4
Diseases of mitotic cell cycle 0.5395852258566725 1.3162427983067382 0.1880925631275731 1.0 0.6120900144146021 12 Q9UJX4,P11802,Q96DE5,Q9UJX6,Q13042,Q9UJX3,Q9H1A4,Q9UJX2 8
The phototransduction cascade 0.8961064982969905 1.2930747077551334 0.1959852217852042 1.0 0.6238787106480285 3 P49356 1
Noncanonical activation of notch3 0.8377224199288323 1.2891454129038673 0.1973475381564831 1.0 0.6253136774842836 2 P67809 1
Activation of ampk downstream of nmdars 0.7007320160674546 1.2725761355020615 0.2031684913971585 1.0 0.6383022413556415 5 P68371,Q9BVA1,Q9BUF5 3
Pregnenolone biosynthesis 0.7002889807278989 1.2707399738644392 0.2038211696166691 1.0 0.6384535267444523 5 P30536 1
Nrif signals cell death from the nucleus 0.831316725978649 1.262879984885632 0.2066323139781936 1.0 0.6410463377894949 2 Q92542 1
Circadian clock 0.5923295561459199 1.2546516031199242 0.2096052618299491 1.0 0.6476991424114643 8 P43490,Q9BWF3,Q86X55 3
Regulation of tp53 activity through acetylation 0.5583348345009373 1.2526038146775085 0.2103499259060943 1.0 0.6485395468385651 10 O95983,P31751 2
Apoptotic factor mediated response 0.791791510137575 1.2476907274044915 0.212144338334725 1.0 0.6511454858953976 4 O60443 1
Insulin receptor signalling cascade 0.694227685483063 1.245615047809882 0.2129057551514301 1.0 0.6513386739817592 5 Q06124,P31751 2
Toll like receptor cascades 0.4281028106644706 1.2438713741752965 0.2135469063684729 1.0 0.6513386739817592 24 P45985,Q15750,O60443,P07858,Q06124,P30154 6
Flt3 signaling 0.790735547778683 1.2436416248744495 0.2136314892797315 1.0 0.6513386739817592 4 Q06124,P31751 2
Downregulation of erbb2 erbb3 signaling 0.8259786476868414 1.2410167457236851 0.2145995628020396 1.0 0.6516668721724113 2 P31751 1
Regulation of tp53 expression and degradation 0.5730787092476082 1.235039223014879 0.2168159068536848 1.0 0.6516668721724113 9 P30154,P30153,P31751 3
Neddylation 0.3640410679277963 1.2350369148701594 0.2168167658361086 1.0 0.6516668721724113 69 Q15369,Q9Y3I1,O00231,P49721,Q96GG9,Q13564,P25788,P28072,Q9BT78,P49720,P61289,P28074,Q99436,O75832,P20618,P28070,Q9UL46,Q9NV06,P60900 19
Hemostasis 0.3372646155510284 1.2275036450028798 0.2196333526699627 1.0 0.6516668721724113 106 Q9NTK5,P68371,P14174,P42785,P10644,P07737,P62993,P53985,Q01650,Q13685,P30154,O43852,Q8NI77,Q96ST3,Q9NUQ9,Q92896,Q06124,P07602,Q9Y624,Q92769,P30153,Q06481,P35613,Q08380,Q9BVA1,Q8NBX0 26
Metabolism of steroids 0.4000901292554843 1.2227090311513726 0.2214396146961086 1.0 0.6516668721724113 39 P30536,Q16850,Q15392,P48449,Q9BWD1,Q86X55,Q15800,P04062 8
Aberrant regulation of mitotic exit in cancer due to rb1 defects 0.5508435722834093 1.2131233253861295 0.2250826732656072 1.0 0.6516668721724113 10 Q9UJX4,Q96DE5,Q9UJX6,Q13042,Q9UJX3,Q9H1A4,Q9UJX2 7
Constitutive signaling by akt1 e17k in cancer 0.8188612099644225 1.2119061452653137 0.225548309525277 1.0 0.6516668721724113 2 P31751 1
Cd28 dependent pi3k akt signaling 0.8188612099644225 1.2119061452653137 0.225548309525277 1.0 0.6516668721724113 2 P31751 1
Rhou gtpase cycle 0.4956271124399901 1.2003897691298433 0.229988000383261 1.0 0.6516668721724113 14 O14964,Q92783 2
Synthesis of substrates in n glycan biosythesis 0.5073341812366855 1.1981528807867097 0.2308575052490638 1.0 0.6516668721724113 13 P16278,P10619 2
Assembly of the orc complex at the origin of replication 0.5655965059275736 1.1971790966071552 0.2312367555651964 1.0 0.6516668721724113 9 O60684,P52294 2
G1 s specific transcription 0.564628023378628 1.1922764156004804 0.2331528789402754 1.0 0.6516668721724113 9 Q9Y619,P00374 2
P75 ntr receptor mediated signalling 0.5176542713586714 1.1920418875092875 0.2332448213407869 1.0 0.6516668721724113 12 Q92542,Q13501,Q9NQC3,Q92769 4
Signaling by notch3 0.5934940443956184 1.1907238791946275 0.2337620003775584 1.0 0.6516668721724113 7 P67809,Q92542,Q9Y6A5 3
Flt3 signaling in disease 0.7749275768425882 1.183061248590796 0.2367848743150991 1.0 0.6516668721724113 4 P62993,Q06124 2
E2f mediated regulation of dna replication 0.5265457683471869 1.1821620193835376 0.2371414196799373 1.0 0.6516668721724113 11 Q9Y619,P30153,P30154 3
Pi 3k cascade fgfr2 0.809608540925282 1.1741429256071363 0.2403377823026238 1.0 0.6516668721724113 2 Q06124 1
Frs mediated fgfr2 signaling 0.809608540925282 1.1741429256071363 0.2403377823026238 1.0 0.6516668721724113 2 Q06124 1
Frs mediated fgfr3 signaling 0.809608540925282 1.1741429256071363 0.2403377823026238 1.0 0.6516668721724113 2 Q06124 1
Pi 3k cascade fgfr3 0.809608540925282 1.1741429256071363 0.2403377823026238 1.0 0.6516668721724113 2 Q06124 1
Frs mediated fgfr4 signaling 0.809608540925282 1.1741429256071363 0.2403377823026238 1.0 0.6516668721724113 2 Q06124 1
Pi 3k cascade fgfr4 0.809608540925282 1.1741429256071363 0.2403377823026238 1.0 0.6516668721724113 2 Q06124 1
Stat5 activation 0.809608540925282 1.1741429256071363 0.2403377823026238 1.0 0.6516668721724113 2 Q06124 1
Frs mediated fgfr1 signaling 0.809608540925282 1.1741429256071363 0.2403377823026238 1.0 0.6516668721724113 2 Q06124 1
Tie2 signaling 0.809608540925282 1.1741429256071363 0.2403377823026238 1.0 0.6516668721724113 2 Q06124 1
Stat5 activation downstream of flt3 itd mutants 0.809608540925282 1.1741429256071363 0.2403377823026238 1.0 0.6516668721724113 2 Q06124 1
Pi 3k cascade fgfr1 0.809608540925282 1.1741429256071363 0.2403377823026238 1.0 0.6516668721724113 2 Q06124 1
Activated ntrk2 signals through frs2 and frs3 0.809608540925282 1.1741429256071363 0.2403377823026238 1.0 0.6516668721724113 2 Q06124 1
Signaling by flt3 itd and tkd mutants 0.809608540925282 1.1741429256071363 0.2403377823026238 1.0 0.6516668721724113 2 Q06124 1
Regulation of signaling by cbl 0.8096085409252667 1.1741429256070743 0.2403377823026486 1.0 0.6516668721724113 2 P46109 1
Erythropoietin activates ras 0.8096085409252667 1.1741429256070743 0.2403377823026486 1.0 0.6516668721724113 2 P46109 1
Antigen activates b cell receptor bcr leading to generation of second messengers 0.8096085409252638 1.1741429256070632 0.2403377823026531 1.0 0.6516668721724113 2 O43865 1
Signaling by vegf 0.4366768740540967 1.1669782249340532 0.2432191633027294 1.0 0.6555927152285752 22 Q16539,P31751,O43865,P04792,Q9UQB8,Q13685,P42345 7
P38mapk events 0.8064056939501769 1.1610951365531614 0.2456032123466047 1.0 0.6581398580850519 2 P11233 1
Activated tak1 mediates p38 mapk activation 0.8064056939501747 1.1610951365531526 0.2456032123466083 1.0 0.6581398580850519 2 Q15750 1
Postmitotic nuclear pore complex npc reformation 0.4257013542967885 1.152564875969961 0.2490890269108812 1.0 0.6623064824064516 23 P55735,Q9BW27,Q9BTX1,Q92973,Q8NFH4,P57740 6
Vitamin d calciferol metabolism 0.8039145907473468 1.1509562368819684 0.2497502400956774 1.0 0.6627801342577746 2 P04062 1
Neutrophil degranulation 0.3547963722702597 1.149041708816695 0.2505387825982039 1.0 0.6635892079628105 163 O75874,P68371,P14174,Q9BTY2,P42785,P08236,O00264,P30519,P04439,P16278,P07858,P09960,O00584,Q8NF37,P01889,Q93050,P06280,O15260,P10253,O95721,P10321,P10619,Q99436,Q92820,P07602,P20618,P07437,Q9H7Z7,P17900 29
Pyruvate metabolism and citric acid tca cycle 0.4038270830585533 1.1463092404825277 0.2516672208524348 1.0 0.6652936936600012 29 P48735,P53985,P21796 3
Unfolded protein response upr 0.3925815949240153 1.143819201616756 0.2526986248842315 1.0 0.6667356025791648 38 O76024,Q5RKV6,O14773,Q96B26,Q9Y5M8,Q92945,Q9Y2L1,Q9UBS4,P43307,P61421 10
Transcriptional regulation by ventx 0.4971517807438598 1.1385974120531492 0.2548711083392674 1.0 0.6698911123399902 13 Q9UJX4,Q96DE5,Q9UJX6,Q9HCE1,Q13042,Q9UJX3,Q9H1A4,Q9UJX2 8
Signaling by wnt 0.3454207116904511 1.1358044053389624 0.2560384329584819 1.0 0.6716725239369736 79 O75832,P25788,P20618,P28074,Q99436,P31751,P40818,Q13363,P30153,P28072,P28070,P49721,Q9UL46,P07737,P60900,P49720,P30154 17
Negative regulation of the pi3k akt network 0.5350179607871401 1.12962708052829 0.2586333950791348 1.0 0.6771851489476585 10 P31751,P30153,Q06124,P30154 4
Signaling by notch2 0.7971530249110315 1.123480854740259 0.2612333272339557 1.0 0.6826897618380711 2 Q92542 1
Synthesis of pg 0.8492046561145523 1.121668534078908 0.2620034001042137 1.0 0.6834005036938807 3 Q8IV08 1
Transcriptional regulation by mecp2 0.493568237386817 1.1176357542406894 0.2637225918782655 1.0 0.6852791591988263 13 Q14739,P42858,Q92769,Q96ST3,Q9HCE1 5
Dna replication initiation 0.6065214749055716 1.1123320965368195 0.2659953885127415 1.0 0.6891823253890348 6 Q07864,Q9NR33 2
Irs mediated signalling 0.7550064073418485 1.1068837004262717 0.2683442138880272 1.0 0.6902503504829989 4 Q06124,P31751 2
Hur elavl1 binds and stabilizes mrna 0.6602305340634138 1.10472402309093 0.2692791906804554 1.0 0.6905627095581026 5 Q01105 1
Keratan sulfate degradation 0.7535424499968439 1.1012962892997331 0.2707677256459433 1.0 0.6918029029971844 4 P06865 1
Cilium assembly 0.3695968391717371 1.0802753766137052 0.2800195712793163 1.0 0.7031768551902957 49 A6NIH7,O94927,Q92973,P68371,O43924,O75935,P07437,Q9BVA1,Q9BW83,O95684 10
Sulfur amino acid metabolism 0.5411949704404111 1.0735980928548727 0.2830028527544295 1.0 0.7059634799619586 9 Q13126 1
Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein 0.4649810263601895 1.0665653930791426 0.2861681347396416 1.0 0.7107961285596417 16 P16278,P10619 2
Mastl facilitates mitotic progression 0.6507763982365418 1.0656223280105082 0.2865944017243624 1.0 0.7107961285596417 5 P30154 1
Carboxyterminal post translational modifications of tubulin 0.6488125572416101 1.057508120251538 0.2902797506249248 1.0 0.7107961285596417 5 Q9BVA1,Q14679 2
Uptake and function of anthrax toxins 0.8289895209449161 1.0483635735754573 0.2944711295844175 1.0 0.7107961285596417 3 P45985 1
Organelle biogenesis and maintenance 0.3386517520161929 1.0477030788894253 0.2947754285937254 1.0 0.7107961285596417 79 A6NIH7,Q9Y512,Q92973,P68371,Q13505,O43924,O75935,P07437,Q86X55,Q9BVA1,P48735,O75964,Q9BW83,O95684 14
Atf4 activates genes in response to endoplasmic reticulum stress 0.4921501481948813 1.0473717593765155 0.2949281513964257 1.0 0.7107961285596417 12 Q92945,Q5RKV6,Q96B26 3
Perk regulates gene expression 0.4701479354882125 1.0465184173767366 0.2953217462327424 1.0 0.7107961285596417 14 Q92945,Q5RKV6,Q96B26 3
Class i mhc mediated antigen processing presentation 0.3232930729576389 1.037314092246676 0.2995895002810951 1.0 0.7155571132255828 104 Q15369,P55735,Q9Y3I1,P55786,O00231,P49721,Q6P179,Q9UIQ6,Q9UJX2,Q9UBS8,P04439,P25788,P01889,Q9NZ08,P28072,Q92990,Q13042,P49720,P10321,P52888,P28074,Q99436,Q9UJX3,Q9UJX4,O75832,P20618,Q9UJX6,P28070,P19474,Q9UL46,P60900 31
Intrinsic pathway for apoptosis 0.4481984748031834 1.027867013429007 0.3040123881319743 1.0 0.722056557237033 18 Q9NR28,P30419,O60443 3
Hyaluronan metabolism 0.7333427835999511 1.0244099987694404 0.3056416612220696 1.0 0.7230006193046198 4 P08236 1
Hyaluronan uptake and degradation 0.7333427835999511 1.0244099987694404 0.3056416612220696 1.0 0.7230006193046198 4 P08236 1
Inhibition of replication initiation of damaged dna by rb1 e2f1 0.6396423440438868 1.0196644605048706 0.3078876222483839 1.0 0.7232081631053274 5 P30154 1
Signaling by fgfr2 0.4247087164385788 1.0176091130657612 0.3088637547968502 1.0 0.7232081631053274 21 P31943,P35269,P30876,P52597,P30153,O15514,P31483,P62993,Q01085,Q06124 10
Signaling by fgfr 0.4247087164385788 1.0176091130657612 0.3088637547968502 1.0 0.7232081631053274 21 P31943,P35269,P30876,P52597,P30153,O15514,P31483,P62993,Q01085,Q06124 10
Negative regulation of fgfr2 signaling 0.730264094137353 1.0127320143970535 0.3111881817778501 1.0 0.7232081631053274 4 P30153,Q06124 2
Negative regulation of fgfr1 signaling 0.730264094137353 1.0127320143970535 0.3111881817778501 1.0 0.7232081631053274 4 P30153,Q06124 2
Negative regulation of fgfr4 signaling 0.730264094137353 1.0127320143970535 0.3111881817778501 1.0 0.7232081631053274 4 P30153,Q06124 2
Spry regulation of fgf signaling 0.730264094137353 1.0127320143970535 0.3111881817778501 1.0 0.7232081631053274 4 P30153,Q06124 2
Negative regulation of fgfr3 signaling 0.730264094137353 1.0127320143970535 0.3111881817778501 1.0 0.7232081631053274 4 P30153,Q06124 2
G alpha i signalling events 0.4318087548391049 1.0113123210032084 0.311866970842146 1.0 0.7232081631053274 20 P07602,P62136,O43865,P30153,P04083,P30154 6
Transport of bile salts and organic acids metal ions and amine compounds 0.8170167319330917 1.0051990652322385 0.3148010052076089 1.0 0.7271161265064636 3 P35613,P53985 2
Regulation of mecp2 expression and activity 0.5262970674763362 0.9982251350155348 0.3181702008379836 1.0 0.7308615795605238 9 Q96ST3,Q14739,P42858,Q92769 4
Golgi associated vesicle biogenesis 0.3829531231100338 0.9963377482078816 0.3190860686273715 1.0 0.7308615795605238 32 Q9H3P7,Q14789,P02786,P11717,O14976,Q9Y5X3,Q99523,O75976,O43493,Q14671,Q92572 11
Extracellular matrix organization 0.4049085166849251 0.9947736930066666 0.3198463436695475 1.0 0.7313819725243654 23 Q32P28,Q9Y624,O14936,P13674,P07858 5
Striated muscle contraction 0.6313101767706919 0.9853576141474976 0.324448441824088 1.0 0.7358672499120184 5 P09493,P08670 2
Ire1alpha activates chaperones 0.4118354315388696 0.9836270811928232 0.3252989046977699 1.0 0.7358672499120184 22 O76024,O14773,Q9Y5M8,Q9UBS4,P43307,P61421 6
Biological oxidations 0.3708396056899543 0.9791213285600784 0.3275200342956228 1.0 0.7380758534058455 42 P07099,Q16850,P78417,P21266,P21964,Q5VT66,Q9NUJ1,O43169 8
Slc transporter disorders 0.3781326679735063 0.9789285137820456 0.3276153022770844 1.0 0.7380758534058455 34 P55735,P53985,Q9BTX1,Q9BW27,Q8NFH4,P35613,P57740,Q12769 8
Post translational modification synthesis of gpi anchored proteins 0.5753295834173243 0.973588615658862 0.330260841140789 1.0 0.7422841917435967 6 O60762,Q96S52,O43292 3
Met activates ptpn11 0.8078134694958339 0.9721738444702316 0.3309640702858476 1.0 0.7422841917435967 3 Q06124 1
Methylation 0.5463456908875017 0.968618385208114 0.3327356268047334 1.0 0.7422841917435967 7 P78417 1
Signalling to ras 0.8066927732289091 0.9681624172451312 0.3329632612911128 1.0 0.7422841917435967 3 P62993,P11233 2
Pi3k akt signaling in cancer 0.546117562921612 0.967547408584237 0.3332704534359005 1.0 0.7422841917435967 7 Q06124,P42345,P31751 3
Urea cycle 0.756583629893255 0.960415219526456 0.3368462812957506 1.0 0.7467748986739844 2 Q9Y619 1
Signaling by notch1 pest domain mutants in cancer 0.5414502789425598 0.9456514295961538 0.3443264033699698 1.0 0.7476932090751651 7 Q92542,Q06330,Q92769 3
Basigin interactions 0.5413640768533559 0.9452473102738044 0.3445326312101271 1.0 0.7476932090751651 7 Q01650,P53985 2
Notch3 activation and transmission of signal to the nucleus 0.7999288002847992 0.9440014524153376 0.3451689060728284 1.0 0.7476932090751651 3 P67809,Q92542 2
Aurka activation by tpx2 0.3974228270667317 0.9381292965686752 0.348177967750189 1.0 0.7476932090751651 23 Q15154,O94927,P68371,P63167,P30153,O75935,Q15691,P07437,Q13561,O95684 10
Raf independent mapk1 3 activation 0.708692006172541 0.9312980508388254 0.3516994099575599 1.0 0.7492726559965406 4 Q06124 1
Synthesis of leukotrienes lt and eoxins ex 0.7956933176682772 0.9289181999405492 0.3529314802154588 1.0 0.7493896014171623 3 Q14914 1
Cooperation of prefoldin and tric cct in actin and tubulin folding 0.4425780306798524 0.925353430178174 0.3547820945047122 1.0 0.7493896014171623 16 Q99471,P68371,O15212,Q9BVA1,P61758,Q9NQP4 6
Regulation of localization of foxo transcription factors 0.5643224997092195 0.9248738764016003 0.3550315167063815 1.0 0.7493896014171623 6 Q9Y3B8,P31751 2
Interactions of vpr with host cellular proteins 0.3713806315142079 0.9191472625672344 0.3580185512373766 1.0 0.7524873301799391 34 P55735,Q9BW27,Q9BTX1,P52294,Q8NFH4,P57740,Q12769 7
Intraflagellar transport 0.4950103276310199 0.918906499529697 0.3581444800346212 1.0 0.7524873301799391 10 P68371,Q9BVA1,Q9BW83 3
Mitotic spindle checkpoint 0.3426817772212631 0.9143476418538076 0.360534204321346 1.0 0.7541902577300094 54 P55735,Q92674,Q8WYP5,Q99661,P57740,Q9H1A4,Q9HBM1,Q9UJX2,O60566,Q13042,Q9Y266,P30154,Q8NI77,Q9BW27,Q96DE5,Q9UJX3,Q7L7X3,Q9UJX4,Q9UJX6,P30153,Q8NFH4,Q8NBT2,Q15691,Q12769 24
Ptk6 regulates proteins involved in rna processing 0.7914564995152219 0.913867771772331 0.3607863299777167 1.0 0.7541902577300094 3 Q07666 1
Heme signaling 0.7030589076376212 0.9101660708541116 0.3627349346047945 1.0 0.7562909745830211 4 P09601 1
Uptake and actions of bacterial toxins 0.5208103549657237 0.9060409697664246 0.3649141677503502 1.0 0.7585791487173947 8 P45985,Q7L0J3 2
Met receptor recycling 0.700968500258165 0.902340237100184 0.3668761573054471 1.0 0.7615039150122139 4 P62993,P46109 2
Sumoylation of ubiquitinylation proteins 0.3743080275364686 0.8923202852989088 0.3722212843818238 1.0 0.7655539904809422 27 P55735,Q9BW27,Q9BTX1,Q8NFH4,P57740,Q12769 6
Regulation of glucokinase by glucokinase regulatory protein 0.3743080275364686 0.8923202852989088 0.3722212843818238 1.0 0.7655539904809422 27 P55735,Q9BW27,Q9BTX1,Q8NFH4,P57740,Q12769 6
Sumoylation of sumoylation proteins 0.3743080275364686 0.8923202852989088 0.3722212843818238 1.0 0.7655539904809422 27 P55735,Q9BW27,Q9BTX1,Q8NFH4,P57740,Q12769 6
Nod1 2 signaling pathway 0.6982192070194989 0.8920616776631122 0.3723598741507019 1.0 0.7655539904809422 4 Q15750,Q13685 2
Activation of bad and translocation to mitochondria 0.517778505792446 0.8913651939719324 0.3727332839950943 1.0 0.7655539904809422 8 Q9Y3B8,P31751 2
Sensory perception 0.3983683949718365 0.884693546193546 0.3763219374389788 1.0 0.7694918240120776 22 P49356,O14936,P30419,P29375 4
Metabolism of folate and pterines 0.5283599652425759 0.8844250501186945 0.3764668053495643 1.0 0.7694918240120776 7 Q9H2D1 1
Mapk3 erk1 activation 0.782612816070603 0.8825818496517823 0.3774622386967277 1.0 0.7695069710132397 3 Q06124 1
Cargo trafficking to the periciliary membrane 0.426025922364506 0.8811180319617773 0.3782539383755812 1.0 0.7699377423376976 18 A6NIH7 1
Gab1 signalosome 0.781913864324298 0.8801170548588708 0.3787959009314474 1.0 0.7699377423376976 3 Q06124 1
Insulin processing 0.5531620823963298 0.8756913976969796 0.3811978231077035 1.0 0.7736736883191854 6 O00471,Q8NEW0 2
Metabolism of cofactors 0.6911969250713297 0.8658838925731389 0.3865538370911836 1.0 0.780919341091408 4 O75874 1
Protein protein interactions at synapses 0.4500152293851442 0.8639529188797029 0.3876137545796274 1.0 0.780919341091408 13 O95197,O14936 2
Binding and uptake of ligands by scavenger receptors 0.5117647694463028 0.8623126343123396 0.3885155020785535 1.0 0.7812222370483938 8 Q07954,Q8WTV0 2
Rho gtpases activate formins 0.335426300671929 0.8616086550150235 0.3889029066356071 1.0 0.7812222370483938 55 P55735,P68371,Q92674,Q8WYP5,P07737,Q99661,Q9BUF5,P57740,Q9HBM1,O60566,Q9Y266,P30154,Q8NI77,Q9BW27,Q7L7X3,P30153,Q8NFH4,P35080,Q8NBT2,Q15691,Q9BVA1,Q12769 22
Synaptic adhesion like molecules 0.6003763219819744 0.8589398717080263 0.3903736902715209 1.0 0.7830302676206531 5 O95197,Q14254,P10586 3
Cell death signalling via nrage nrif and nade 0.5088377243348067 0.8482023200808282 0.3963253053889048 1.0 0.7903463938860137 8 Q9NY61,Q92542,Q13501 3
Suppression of phagosomal maturation 0.5154308036335986 0.8243018986379289 0.4097680400709373 1.0 0.8047514132869144 7 P52294 1
Interleukin 12 family signaling 0.3641731314539822 0.8200268171131724 0.4122008196351476 1.0 0.8047514132869144 30 P11233,P52597,P14174,P78417,O14979,Q13126,Q53EL6,P22626 8
Gap junction assembly 0.7636169455322331 0.8160473225409592 0.4144730705317108 1.0 0.8047514132869144 3 Q9BVA1,P68371 2
Transport of connexons to the plasma membrane 0.7636169455322331 0.8160473225409592 0.4144730705317108 1.0 0.8047514132869144 3 Q9BVA1,P68371 2
Degradation of the extracellular matrix 0.5392198391629818 0.8146374208562744 0.4152798838244427 1.0 0.8047514132869144 6 Q92542,P07858 2
Tp53 regulates transcription of genes involved in g2 cell cycle arrest 0.5115346464525344 0.8062689095762391 0.420087813085559 1.0 0.8106335858697425 7 Q99873,Q86X55 2
Signaling by hippo 0.6747856142668346 0.805182166528768 0.4207145659335334 1.0 0.810702787164056 4 Q4VCS5,Q07157 2
Collagen biosynthesis and modifying enzymes 0.4858888196360482 0.7954082777619675 0.4263760463362644 1.0 0.814746428375146 9 Q32P28,P13674 2
Amino acids regulate mtorc1 0.4557150469791127 0.7936731297625971 0.4273857469330964 1.0 0.8155399788486901 11 P55735,P61421,P42345,P36543 4
Recruitment of numa to mitotic centrosomes 0.3612444309808732 0.7863047699940328 0.4316889586412507 1.0 0.8176073325540147 27 Q9BVA1,Q15154,O94927,P68371,P30153,O75935,Q15691,Q9BSJ2,P07437,Q13561,Q9BUF5,O95684 12
Pkmts methylate histone lysines 0.4689857982432057 0.7833011832562079 0.4334502685538228 1.0 0.8176073325540147 10 Q9BYW2,Q03164,O96028 3
Downregulation of erbb2 signaling 0.5316329134514447 0.7816362344262084 0.434428385883292 1.0 0.8176073325540147 6 Q16543,P31751 2
Beta oxidation of very long chain fatty acids 0.6675509809774562 0.7786632788023015 0.4361780928028831 1.0 0.8186986847065751 4 Q15067,O75521 2
Fgfr2 alternative splicing 0.4180524928865222 0.7724461298271982 0.4398502412303966 1.0 0.8210537836300738 16 P31943,P35269,P30876,P52597,O15514,P31483,Q01085 7
Signaling by wnt in cancer 0.5029039267374995 0.7664882854005866 0.4433858195866214 1.0 0.8228421353966636 7 P30153,P30154 2
Met activates rap1 and rac1 0.5763705009865215 0.7623539461541117 0.445848784936095 1.0 0.8228421353966636 5 P46109 1
Beta catenin phosphorylation cascade 0.5759385292976998 0.7606319627522286 0.4468769231452569 1.0 0.8228421353966636 5 P30154 1
Signaling by ctnnb1 phospho site mutants 0.5759385292976998 0.7606319627522286 0.4468769231452569 1.0 0.8228421353966636 5 P30154 1
Disassembly of the destruction complex and recruitment of axin to the membrane 0.5759385292976998 0.7606319627522286 0.4468769231452569 1.0 0.8228421353966636 5 P30154 1
Diseases associated with glycosylation precursor biosynthesis 0.5008931217882451 0.757256026785525 0.448896490003392 1.0 0.8233769843377726 7 P10619 1
Death receptor signalling 0.4150217424247546 0.7537490912482931 0.4509998981557246 1.0 0.8261306545656264 16 Q9NQC3,Q92769,Q9NY61,Q92542,Q15750,Q13501 6
Vitamin b5 pantothenate metabolism 0.6578003038267405 0.7431863042772043 0.4573688939859024 1.0 0.8344549501976837 4 Q9NVE7,Q9NRN7 2
Regulation of glycolysis by fructose 2 6 bisphosphate metabolism 0.6571662827258369 0.740890697141134 0.4587597165380424 1.0 0.8352267716164717 4 P30154 1
Rho gtpases activate iqgaps 0.4738273104287293 0.7357332173014264 0.4618930703212036 1.0 0.8380086851693413 9 Q9BVA1 1
Transcriptional activation of mitochondrial biogenesis 0.4447783570117298 0.7347686968315337 0.4624803743956271 1.0 0.8380086851693413 11 P48735 1
Negative regulation of mapk pathway 0.4849003369270803 0.7337632270674161 0.4630930560731308 1.0 0.8380086851693413 8 P30086,Q02750,P30154 3
Dna damage reversal 0.6549685723932543 0.7329445198487695 0.4635922682533018 1.0 0.8380086851693413 4 Q8N3C0,Q9C0B1 2
Cyclin a b1 b2 associated events during g2 m transition 0.471287704251461 0.7232420561674974 0.4695311848599761 1.0 0.8398915066856418 9 P30154 1
Sumoylation of rna binding proteins 0.3493452826431253 0.7160929707807705 0.47393394384448 1.0 0.8466632434305035 33 P55735,Q9BW27,Q9BTX1,Q8IXK0,Q8NFH4,P61978,P57740,Q12769 8
Notch hlh transcription pathway 0.6497197400552057 0.7140382331664532 0.4752035380320043 1.0 0.847827378647477 4 Q92769 1
Nephrin family interactions 0.4905476129958225 0.7099993038347232 0.4777045678864882 1.0 0.8511826845977426 7 O14936,O43707 2
O linked glycosylation of mucins 0.642307755144548 0.6875215906157996 0.4917540999162857 1.0 0.863740685738323 4 Q86SF2,O43505 2
O linked glycosylation 0.6423077551445477 0.6875215906157982 0.4917540999162866 1.0 0.863740685738323 4 Q86SF2,O43505 2
Signal amplification 0.5090784271698007 0.6847179162508052 0.4935219411249996 1.0 0.864136585402988 6 Q13685 1
Recruitment of mitotic centrosome proteins and complexes 0.3478311988172821 0.6817479278709433 0.4953983558197552 1.0 0.8658427314454831 25 Q15154,O94927,P68371,P30153,P21127,O75935,Q15691,Q9BSJ2,P07437,Q13561,O95684 11
Interleukin 17 signaling 0.40838785744858 0.679370102539772 0.496903388448022 1.0 0.8673682556624507 14 P45985,P30153,Q02750,Q15750,P30154 5
Nr1h2 and nr1h3 mediated signaling 0.5547832733276944 0.6771519921120767 0.4983095239843238 1.0 0.8687174928926203 5 Q8NB78,P49327 2
Autophagy 0.3394746494392944 0.6678718730718687 0.50421538296948 1.0 0.8708901775615971 40 Q9BVA1,P21796,Q8N4H5,Q9NS69 4
Signaling by flt3 fusion proteins 0.7196445985561777 0.6664929116719177 0.5050960928961732 1.0 0.8708901775615971 3 P62993 1
M phase 0.3282380236963566 0.664892317613654 0.5061193697769752 1.0 0.8708901775615971 183 P55735,Q01105,Q99567,P68371,Q92674,O60216,O00231,P49721,Q8WYP5,Q99661,Q9Y6X3,Q9BUF5,Q9UJX2,Q9H1A4,Q9HBM1,O95684,P57740,Q15154,P50402,P25788,Q92973,P28072,O75935,Q13042,P49720,P30154,Q8NI77,Q9BW27,P61289,P28074,Q99436,Q96DE5,Q9UJX3,P42166,O43633,Q7L7X3,O94927,Q14739,O75832,Q9UJX4,P20618,Q9BTX1,Q8IXJ6,Q9UJX6,Q86XL3,Q8NFH4,P30153,P28070,Q8NBT2,Q9UL46,Q15691,P07437,Q9BVA1,P60900,Q12769 55
Plasma lipoprotein assembly remodeling and clearance 0.410123174955378 0.6372270693920277 0.5239769478706271 1.0 0.8769167290213484 13 Q8WTV0 1
Transport of the slbp dependant mature mrna 0.3418509340079068 0.6353866239058682 0.5251762898023924 1.0 0.8769167290213484 30 P55735,Q9BW27,Q9BTX1,Q8NFH4,P57740,Q12769 6
Regulation of beta cell development 0.7079767766368776 0.6281197138861159 0.5299255196213384 1.0 0.8769167290213484 3 P31751 1
Plasma lipoprotein clearance 0.4237889909951834 0.6234841213183401 0.5329664335959885 1.0 0.8769167290213484 11 Q8WTV0 1
Anchoring of the basal body to the plasma membrane 0.3477484323759786 0.6228174629686991 0.5334044813257122 1.0 0.8769167290213484 24 P68371,O75935,O95684,P07437 4
Constitutive signaling by overexpressed erbb2 0.7059451762193025 0.6215038953525265 0.5342681323098137 1.0 0.8769167290213484 3 P62993,Q16543 2
Adaptive immune system 0.3219795590271262 0.6165198980196025 0.5375514433975175 1.0 0.8797345780354144 169 Q15369,P55735,P68371,Q9Y3I1,P55786,O00231,P49721,Q6P179,P62993,Q9UIQ6,Q9UJX2,P04439,P07858,P25788,P01889,Q9NZ08,P28072,Q92990,O75935,P62942,P49720,P30154,P10321,Q8NI77,P10619,P28074,Q99436,O43865,Q9UJX3,Q06124,Q9UJX4,O75832,P20618,P31751,Q5KU26,Q9UJX6,P30153,P28070,P19474,Q9UL46,Q9BVA1,P60900,P42345 43
Darpp 32 events 0.4487799754300361 0.6139411555057669 0.5392542129211251 1.0 0.8797345780354144 9 P62136,P30153,P30154 3
Activation of ppargc1a pgc 1alpha by phosphorylation 0.6640569395017816 0.609674050861676 0.5420777473082323 1.0 0.8808277781344791 2 Q16539 1
Mhc class ii antigen presentation 0.3229605007277132 0.6045365427535888 0.545486981504772 1.0 0.8835987469002919 49 P55735,P10619,O75935,Q9BVA1,P07858 5
Signaling by met 0.3860081729961733 0.5976844322015077 0.5500505149575652 1.0 0.8878462429667993 17 Q92783,O14964,P40818,P46109,Q06124 5
Tp53 regulates transcription of cell death genes 0.6159966535928926 0.5953464257133771 0.5516119289408477 1.0 0.8893202896672656 4 Q92696,P49327 2
Signaling by notch1 0.4546266821412459 0.5925488068307321 0.5534831481598421 1.0 0.8912897644076331 8 Q92542,Q06330,Q92769 3
Mtor signalling 0.4173696636218805 0.5900343190189206 0.5551676413636009 1.0 0.8913802758427238 11 P62942,P23588,P42345,P31751 4
Alpha oxidation of phytanate 0.6139462647480337 0.5883065453286974 0.5563265530490975 1.0 0.8913802758427238 4 Q9BY49 1
Interleukin 4 and interleukin 13 signaling 0.4092630675033192 0.5873226384889247 0.5569870396525138 1.0 0.8913802758427238 12 P04083,Q07820,P09601 3
Nuclear pore complex npc disassembly 0.3349262293822163 0.582664970928798 0.5601188586222956 1.0 0.8913802758427238 31 P55735,Q9BW27,Q9BTX1,Q8NFH4,P57740,Q12769 6
Ptk6 regulates cell cycle 0.6562277580071155 0.5821204019415133 0.560485583770074 1.0 0.8913802758427238 2 P11802 1
Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects 0.6562277580071155 0.5821204019415133 0.560485583770074 1.0 0.8913802758427238 2 P11802 1
Attachment of gpi anchor to upar 0.6085648404127406 0.5699385685010682 0.5687193646518838 1.0 0.8978948882207283 4 Q96S52,O43292 2
Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand 0.3337741305858863 0.568134885943783 0.5699433810698351 1.0 0.8978948882207283 29 P68371,Q9BVA1,O75935 3
Extra nuclear estrogen signaling 0.4261736882470415 0.5665546113965838 0.5710168196701073 1.0 0.8978948882207283 10 Q99873,P31751 2
Export of viral ribonucleoproteins from nucleus 0.3331242188301008 0.5629811495882409 0.5734477200750521 1.0 0.8978948882207283 29 P55735,Q9BW27,Q9BTX1,Q8NFH4,P57740,Q12769 6
Dap12 interactions 0.5203621979680473 0.5458270005383645 0.5851848614135329 1.0 0.9079189563490596 5 P10321,P01889 2
Deadenylation of mrna 0.4083450360337459 0.5435749565924294 0.5867339970863794 1.0 0.9079189563490596 11 Q9H074,P23588 2
Nuclear envelope ne reassembly 0.3152497164041173 0.5432307622100054 0.586970928776688 1.0 0.9079189563490596 50 Q9BVA1,P55735,P50402,Q9BW27,Q14739,Q9BTX1,Q92973,P68371,P30153,Q8NFH4,Q86XL3,Q8WYP5,Q9BUF5,Q8IXJ6,P57740,Q12769,P42166,O43633 18
Notch1 intracellular domain regulates transcription 0.4738582094230042 0.5382912778872848 0.5903759719716455 1.0 0.908511016175328 6 Q06330,Q92769 2
Map3k8 tpl2 dependent mapk1 3 activation 0.5990055349099168 0.5377185252794896 0.590771387773837 1.0 0.908511016175328 4 Q02750,P45985 2
Glycogen storage diseases 0.6792475303534556 0.5365753992640337 0.5915609408717422 1.0 0.908511016175328 3 P10253 1
Abc transporters in lipid homeostasis 0.6427046263345311 0.5355835136775844 0.5922464253053847 1.0 0.908511016175328 2 P40855 1
Pp2a mediated dephosphorylation of key metabolic factors 0.6784308480413228 0.5340407851663639 0.5933133166859286 1.0 0.908511016175328 3 P30154 1
Mitotic prometaphase 0.2940666119078125 0.5311522647471131 0.5953132688743619 1.0 0.9105571960932268 83 P55735,P68371,Q92674,O60216,Q8WYP5,Q99661,Q9BUF5,P57740,Q9HBM1,O95684,Q15154,O60566,O75935,Q9Y266,P30154,Q8NI77,Q9BW27,P49454,Q9BSJ2,Q7L7X3,O94927,P30153,Q8NFH4,Q8NBT2,Q15691,P07437,Q9BVA1,Q12769 28
Cd163 mediating an anti inflammatory response 0.6391459074733195 0.5235731805723758 0.6005754392996043 1.0 0.913462675349029 2 Q16539 1
Signal regulatory protein family interactions 0.6712584331267798 0.5119559956124531 0.608681807181799 1.0 0.9192017934793892 3 Q06124 1
Hcmv early events 0.3217558301463124 0.5086365329715864 0.6110070165452592 1.0 0.9192017934793892 40 P55735,Q9BW27,Q9BTX1,Q99567,P68371,Q8NFH4,P83916,Q9BVA1,P57740,Q12769 10
Post translational protein modification 0.2808208163498218 0.5053827100024 0.6132900603271865 1.0 0.9192017934793892 353 Q92734,Q86SF2,Q5VTR2,Q99567,Q9Y3I1,Q13363,P21796,Q10472,O00231,P45880,P49721,O00743,Q14258,Q15022,Q14789,Q13564,Q02818,P46977,P38435,P28072,Q12888,O43505,Q5H9R7,O75935,P10619,P28074,O60725,P20618,Q8NB78,Q06481,P28070,P60900,P55735,Q96FW1,Q9BTY2,P04439,P16278,Q96IJ6,Q92696,Q14679,O43852,Q92783,Q99436,Q9NXR7,P61978,Q96K76,O14964,Q8NFH4,Q96PC5,Q9BVA1,Q15369,P68371,O43493,Q9UPU5,P57740,Q8TEY7,P25788,Q9BU89,Q8NBJ4,P49720,Q9HA64,Q15750,O75832,Q96RU2,P04066,O60216,Q96GG9,Q8N6H7,P04844,Q12907,Q9BW27,Q8IXK0,Q12955,O15027,Q96ST3,Q9BTX1,Q92769,P40818,Q9UL46,Q9NV06,Q12769 81
Signaling by fgfr1 0.509018475262821 0.5041049934637927 0.6141875981198472 1.0 0.9192017934793892 5 P30153,Q06124 2
Signaling by fgfr3 0.509018475262821 0.5041049934637927 0.6141875981198472 1.0 0.9192017934793892 5 P30153,Q06124 2
Signaling by fgfr4 0.509018475262821 0.5041049934637927 0.6141875981198472 1.0 0.9192017934793892 5 P30153,Q06124 2
Egfr downregulation 0.4348752959021802 0.5035274269847863 0.6145935021696252 1.0 0.9192017934793892 8 O14964,Q92783 2
Met activates ras signaling 0.5872348494772675 0.4988171312263915 0.6179082177699475 1.0 0.920486573305379 4 P62993 1
Syndecan interactions 0.5836745582813578 0.4872298985789756 0.6260954195612296 1.0 0.9236590490731258 4 P12814,O14936 2
Non integrin membrane ecm interactions 0.5836745582813578 0.4872298985789756 0.6260954195612296 1.0 0.9236590490731258 4 P12814,O14936 2
Cell cell communication 0.3350817221115374 0.4810106135092403 0.6305089554713272 1.0 0.9249260215466776 23 O14936,Q06124 2
Activation of nmda receptors and postsynaptic events 0.358887322312455 0.4782394040290398 0.632479819789687 1.0 0.9249260215466776 19 P68371,Q14168,P10644,Q9BVA1,Q9BUF5,O14936 6
Runx1 regulates genes involved in megakaryocyte differentiation and platelet function 0.4079269420346967 0.4781394474681848 0.632550957087644 1.0 0.9249260215466776 10 Q03164,Q99873,Q96ST3 3
Complex i biogenesis 0.346485555981144 0.4730331835828265 0.6361895048433284 1.0 0.9273951443457368 21 P03886,O75306,Q9Y6M9,O43676 4
Prolonged erk activation events 0.5758345506647583 0.4620254690385906 0.6440630562222076 1.0 0.9351188940950288 4 Q02750 1
Toll like receptor tlr1 tlr2 cascade 0.3680728446954213 0.4619920892877451 0.6440869933817801 1.0 0.9351188940950288 15 P45985,P30153,Q02750,Q15750,P30154 5
E2f enabled inhibition of pre replication complex formation 0.4541986412905385 0.4601582095261532 0.6454026649075311 1.0 0.9358575402968424 6 Q9UBD5,Q9Y619 2
Neurexins and neuroligins 0.4154340942385943 0.4583682540179085 0.6466878952380197 1.0 0.9358575402968424 9 O14936 1
Maturation of sars cov 2 nucleoprotein 0.647561409754364 0.4413893402653631 0.6589311580022272 1.0 0.9406022392478224 3 Q99873,P48729 2
Hiv infection 0.2958065643868002 0.4399301798196404 0.65998767674352 1.0 0.9406022392478224 130 P04439,P55735,P30419,Q15369,P25788,P28074,P20618,Q99436,P52294,Q8NFH4,P28072,P57740,P28070,P49721,P60900,Q92804 16
Tysnd1 cleaves peroxisomal proteins 0.5629472252274301 0.4215825347821977 0.6733297565288938 1.0 0.9436245413254774 4 Q15067 1
Formation of tc ner pre incision complex 0.3192184699265604 0.4160668584438156 0.6773610803765528 1.0 0.946374136737913 24 Q16531,P30876,P19387,P18074,O15514,Q99627,Q92905,Q9BT78,Q9UNS2,Q93009,Q7L5N1 11
Glycogen breakdown glycogenolysis 0.4220107326005975 0.4127566069906644 0.6797849466072019 1.0 0.9478302304319928 7 P10253 1
Sumoylation of chromatin organization proteins 0.3108465014653176 0.4087480671451536 0.68272455506923 1.0 0.9480749894281212 35 P55735,Q15022,Q9BW27,Q9BTX1,Q92769,Q99567,Q8IXK0,Q8NFH4,P57740,Q12769 10
Copi independent golgi to er retrograde traffic 0.3105694884467475 0.401688731670911 0.687913118472179 1.0 0.9529563857558244 25 P68371,Q9BVA1,O75935 3
Processing of dna double strand break ends 0.3495713981011902 0.4000785231873374 0.6890986821972513 1.0 0.9529563857558244 18 O96028,Q9UQ84 2
Formation of tubulin folding intermediates by cct tric 0.378814707230415 0.3973603469867853 0.6911017520605287 1.0 0.9529563857558244 11 Q9BVA1 1
Resolution of sister chromatid cohesion 0.2928433664222834 0.3899792151765529 0.6965519164396028 1.0 0.9553931646384024 59 P55735,P68371,Q92674,O60216,Q8WYP5,Q99661,Q9BUF5,P57740,Q9HBM1,O60566,Q9Y266,P30154,Q8NI77,Q9BW27,Q7L7X3,P30153,Q8NFH4,Q8NBT2,Q15691,Q9BVA1,Q12769 21
Role of phospholipids in phagocytosis 0.6292966884625777 0.3897825086582184 0.6966973788879072 1.0 0.9553931646384024 3 Q8IV08 1
Opioid signalling 0.3523968816094096 0.3866171475483385 0.6990396613927241 1.0 0.9571680792722728 16 P62136,P30154,O43865,P30153 4
Cdc6 association with the orc origin complex 0.5493534760196361 0.3803640632494683 0.7036751868755653 1.0 0.9615959725032625 4 Q9Y619,Q9UBD5 2
Response of mtb to phagocytosis 0.3739275134631497 0.3742049473824803 0.7082518434772545 1.0 0.9648206569989832 11 P52294 1
Infection with mycobacterium tuberculosis 0.3739275134631497 0.3742049473824803 0.7082518434772545 1.0 0.9648206569989832 11 P52294 1
Rhobtb2 gtpase cycle 0.3359288263585108 0.3706847052268482 0.7108723834939532 1.0 0.9656495388937932 20 Q16543,P12814,P38159,Q99832,P62995,Q96DH6,P07900 7
Fcgamma receptor fcgr dependent phagocytosis 0.3240022564524699 0.3657215143545991 0.7145728905409987 1.0 0.9668579939075448 22 Q9UQB8 1
Signaling by erbb2 0.3941292850987568 0.3645983590542318 0.7154112399319625 1.0 0.9670386415632044 9 Q16543,P40818,P31751 3
Glutathione conjugation 0.3714644823278548 0.3626654259567649 0.7168548298711956 1.0 0.9670843919206296 11 P78417 1
Regulation of plk1 activity at g2 m transition 0.3055465851211585 0.3521115017417 0.7247546429345015 1.0 0.9729582877750842 29 P68371,O75935,O95684,P07437 4
Foxo mediated transcription 0.3644585116384107 0.330346177208237 0.7411384050971968 1.0 0.9793077029209551 11 P31751,Q92769,Q96ST3 3
Activation of the pre replicative complex 0.3337939605644162 0.3280092125724111 0.7429046970199529 1.0 0.9793077029209551 19 P24941,Q9UBD5,Q07864,Q13416,P15927,Q9Y619,P49643,Q9NR33 8
Mitochondrial biogenesis 0.3023469992235147 0.3277955175812106 0.7430662766988423 1.0 0.9793077029209551 30 Q9NX63,Q9Y512,Q13505,Q86X55,P48735,O75964,Q00059 7
Mtorc1 mediated signalling 0.3966465217271036 0.3135061318428299 0.7538961628029486 1.0 0.9869709306924096 7 P62942,P23588 2
Foxo mediated transcription of oxidative stress metabolic and neuronal genes 0.5224570962070623 0.3036908797898855 0.7613634069206181 1.0 0.9878118452387878 4 Q96ST3 1
Metabolism of fat soluble vitamins 0.5955399005158168 0.3017237020262475 0.7628626982617093 1.0 0.9878118452387878 3 P29375 1
Nuclear import of rev protein 0.2984052903250817 0.2989191163549201 0.765001760853991 1.0 0.9878118452387878 31 P55735,Q9BW27,Q9BTX1,Q8NFH4,P57740,Q12769 6
Erks are inactivated 0.4101313354452611 0.2983036566318958 0.7654714136822951 1.0 0.9878118452387878 6 P30154 1
Peroxisomal lipid metabolism 0.3568721901745501 0.2962458564383854 0.7670423312569081 1.0 0.9881521863704018 11 Q9BY49,P51648,O15254 3
Nuclear signaling by erbb4 0.5906506799354053 0.2898303996880154 0.7719459899735195 1.0 0.9898833940274052 3 Q92542 1
Chk1 chk2 cds1 mediated inactivation of cyclin b cdk1 complex 0.3636688079942979 0.2796360241402836 0.7797567659721574 1.0 0.99208816726646 10 P31946,Q9Y3B8,P63104,P14635,P27348,P62258,P61981,Q04917,O96017 9
Reduction of cytosolic ca levels 0.5855137497616033 0.2775835159000258 0.7813320874439909 1.0 0.99208816726646 3 P30626 1
Platelet calcium homeostasis 0.5855137497616033 0.2775835159000258 0.7813320874439909 1.0 0.99208816726646 3 P30626 1
Aggrephagy 0.3466597247572166 0.2773284128029125 0.78152794458178 1.0 0.99208816726646 12 P68371,P63167,P08670,O43237,Q9BVA1,Q9BUF5 6
Raf activation 0.3787575871538711 0.2717514739560798 0.7858131195800553 1.0 0.99208816726646 8 Q02750,P30154 2
Deactivation of the beta catenin transactivating complex 0.3848092969279575 0.2699940532854029 0.7871648285657196 1.0 0.99208816726646 7 P31751 1
Tryptophan catabolism 0.5822240828011362 0.2698768488613637 0.7872549984683039 1.0 0.99208816726646 3 Q01650 1
Myd88 independent tlr4 cascade 0.3259093999426793 0.2684332178119356 0.7883658733123764 1.0 0.99208816726646 18 P45985,P30153,Q02750,Q15750,Q06124,P30154 6
G beta gamma signalling through cdc42 0.5519572953736572 0.2677417665882621 0.7888980980231106 1.0 0.99208816726646 2 P63218 1
G2 m dna damage checkpoint 0.2925488497875316 0.2626298971330619 0.7928358541582501 1.0 0.9923472849628864 28 O96028,Q9UQ84 2
Deadenylation dependent mrna decay 0.2929005155282699 0.2610359139758496 0.794064811754664 1.0 0.9923472849628864 33 Q9H074,Q5RKV6,Q969T7,Q96B26,P23588,Q6PGP7,Q96C86 7
Wnt mediated activation of dvl 0.5462633451957223 0.2540469110061427 0.7994593168843875 1.0 0.9923472849628864 2 P19784 1
Cargo recognition for clathrin mediated endocytosis 0.29152276723842 0.2496381059470603 0.8028672270725101 1.0 0.9932676605441696 31 P02786,Q92783,P11717,O14964,Q96D71,Q99627,Q92905,O43493,Q14108,Q9BT78,P62993,Q9UNS2,Q7L5N1 13
Cyclin d associated events in g1 0.3717616220804477 0.2457701482156272 0.805860166661934 1.0 0.995175651359292 8 P30153,P63208,P30154 3
Gap junction trafficking and regulation 0.3551333995843427 0.2447362465496341 0.8066606606242686 1.0 0.9952683690436118 10 Q9BVA1,P68371,Q07157 3
Post chaperonin tubulin folding pathway 0.3701558221484545 0.2399162170729377 0.8103952085665402 1.0 0.9977038857719892 8 P68371,Q9BVA1,P36404 3
Translocation of slc2a4 glut4 to the plasma membrane 0.2891298463418527 0.2341039127609851 0.8149043083857148 1.0 0.9982577777725006 30 Q9BVA1,P31751,P68371,O00471,Q9UIQ6 5
Met promotes cell motility 0.3892425333193796 0.2297776043355671 0.8182645882802124 1.0 0.9990530794716772 6 P46109 1
Rnd1 gtpase cycle 0.3392605717701351 0.221093308173223 0.8250197806424273 1.0 0.9990530794716772 11 O75976,P38159 2
Signaling by erbb4 0.3849953142520654 0.2166049337844899 0.8285162404182742 1.0 1.0 6 P62993,Q92542 2
Hdms demethylate histones 0.3674949743659085 0.2100848431581731 0.8336014549184139 1.0 1.0 7 Q8NB78 1
Toll like receptor 9 tlr9 cascade 0.3160136168339969 0.2083675126947687 0.8349420207162859 1.0 1.0 17 P45985,P30153,Q02750,Q15750,P30154 5
The citric acid tca cycle and respiratory electron transport 0.2699791626404177 0.2045046617772042 0.8379591494044119 1.0 1.0 80 P21912,O43676,O75964,P21796,O75306,P47985,P48735,P53985 8
Trans golgi network vesicle budding 0.2849691424204796 0.2035711716913043 0.8386886230345101 1.0 1.0 40 Q9H3P7,Q14789,P11717,O14976,O14964,Q9Y5X3,Q99523,O75976,O43493,Q14671,Q92572,O43633 12
Receptor mediated mitophagy 0.5464578141687446 0.1932701924903238 0.8467473691482872 1.0 1.0 3 Q96HS1,P19784 2
Leishmania infection 0.2823057909797348 0.1910165935952976 0.8485125927150325 1.0 1.0 29 Q9UQB8 1
Integrin cell surface interactions 0.474778222810581 0.1863611735795238 0.852161538006825 1.0 1.0 4 Q9Y624 1
Glycogen metabolism 0.339796335150497 0.1854163360611409 0.8529024962497285 1.0 1.0 10 P10253,P35573 2
Activation of bh3 only proteins 0.3249135363522115 0.1851177153575474 0.8531367069003191 1.0 1.0 12 P63167,Q13625,Q9Y3B8,P31751 4
Mecp2 regulates neuronal receptors and channels 0.3559245024356461 0.1727726971321698 0.8628300988052529 1.0 1.0 7 Q96ST3 1
Transport of mature mrnas derived from intronless transcripts 0.2798880741418313 0.169813355615491 0.86515692321972 1.0 1.0 36 P55735,Q9BW27,Q9BTX1,Q99567,Q8NFH4,Q92797,P57740,Q12769 8
Interactions of rev with host cellular proteins 0.2792014893810879 0.1656498102490652 0.8684325458472091 1.0 1.0 34 P55735,Q9BW27,Q9BTX1,Q8NFH4,P57740,Q12769 6
Phase ii conjugation of compounds 0.2765231780747272 0.1631310841457967 0.8704152259956648 1.0 1.0 27 P78417,Q9NUJ1,P21266 3
Cd209 dc sign signaling 0.5014234875444739 0.1611295283612976 0.8719913838331701 1.0 1.0 2 P17612 1
Sema4d mediated inhibition of cell attachment and migration 0.5007117437722308 0.1598730347828042 0.8729810903968944 1.0 1.0 2 Q9NWH9 1
Nef and signal transduction 0.5007117437722307 0.1598730347828036 0.8729810903968949 1.0 1.0 2 Q13177 1
Transport and synthesis of paps 0.5260853267924365 0.1557912140622196 0.8761975962275468 1.0 1.0 3 Q8TB61 1
Rap1 signalling 0.5129939480242047 0.1341418816610133 0.8932903821225648 1.0 1.0 3 P17612,P31946 2
Smooth muscle contraction 0.309894575564288 0.1277774326995761 0.8983251097440224 1.0 1.0 12 P60660,P04083 2
Telomere c strand synthesis initiation 0.4412393162393149 0.120075429528942 0.9044233959417156 1.0 1.0 4 P49642,P49643,Q9NYB0 3
Ephrin signaling 0.5008899964400155 0.1158277731046939 0.9077890389000838 1.0 1.0 3 Q13177,Q14155 2
Initiation of nuclear envelope ne reformation 0.2942995615954627 0.1152232535186334 0.9082681677841162 1.0 1.0 18 Q14739,P50402,Q86XL3,P30153,Q8IXJ6 5
Kinesins 0.295702327593332 0.1147222577287213 0.908665271290251 1.0 1.0 16 P68371,Q8NI77,Q99661,Q9BVA1 4
Sumoylation of dna replication proteins 0.2705748198666042 0.1082859021095763 0.9137689053416284 1.0 1.0 33 P55735,Q9BW27,Q9BTX1,Q8NFH4,P57740,Q12769 6
Tristetraprolin ttp zfp36 binds and destabilizes mrna 0.3032098263190976 0.1041014397392129 0.9170888483212392 1.0 1.0 12 Q96B26,Q92973 2
Sumoylation of dna damage response and repair proteins 0.2712325905051225 0.1033824725132119 0.9176594225104288 1.0 1.0 41 P55735,Q9BW27,Q9BTX1,Q8IXK0,Q8NFH4,O60216,P57740,Q12769 8
G alpha q signalling events 0.3298735776122001 0.0976349762826142 0.9222221501206558 1.0 1.0 7 P04083 1
Biosynthesis of specialized proresolving mediators spms 0.4810498289083572 0.0893104068912939 0.9288352236191662 1.0 1.0 3 Q14914 1
Rhobtb gtpase cycle 0.2654181422778954 0.0874680213640306 0.930299503239156 1.0 1.0 29 Q16543,Q5VTR2,P12814,P08670,P38159,Q8N684,Q99832,P62995,Q96DH6,Q9BT78,P07900 11
G0 and early g1 0.3630210188813559 0.0861162935425403 0.9313739713670436 1.0 1.0 5 P12004,P11388,Q13547,P24941 4
Rho gtpases activate nadph oxidases 0.3612397577484838 0.082815037077596 0.9339986123417549 1.0 1.0 5 Q16539,P05771,P63000,Q99570 4
Tp53 regulates transcription of cell cycle genes 0.2956730256340084 0.0788469995121384 0.9371543201801298 1.0 1.0 12 Q99873,Q9Y3B8,Q86X55 3
Tp53 regulates transcription of death receptors and ligands 0.4705275875702158 0.0769741955881413 0.9386440729857786 1.0 1.0 3 P49327 1
Muscle contraction 0.2627211545390508 0.0709078210276806 0.943471118766308 1.0 1.0 24 O43865,P60660,P08670,P04083 4
Amyloid fiber formation 0.3285931524112971 0.0697429109930811 0.9443982868804603 1.0 1.0 6 Q9Y287 1
Dna damage recognition in gg ner 0.2781407119853652 0.0564174856343192 0.9550092276181186 1.0 1.0 14 Q99627,Q92905,Q9BT78,Q9UNS2,Q16531,Q7L5N1 6
Polo like kinase mediated events 0.396011396011392 0.0532911988926042 0.9574998925050596 1.0 1.0 4 P14635,O95067,P49454 3
Nonhomologous end joining nhej 0.2859404687364714 0.0485714150361266 0.9612608505645348 1.0 1.0 12 O96028 1
Protein folding 0.2607171547121439 0.0484473097037512 0.9613597558547018 1.0 1.0 33 Q99471,P36404,P68371,O15212,P04062,Q9BVA1,P61758,Q9Y2T2,Q9NQP4 9
Transcriptional regulation by e2f6 0.317599284859919 0.0476896522513762 0.961963581027946 1.0 1.0 6 Q15022,P31350 2
Regulation of cytoskeletal remodeling and cell spreading by ipp complex components 0.3857651245551604 0.0393572045780779 0.9686055992530735 1.0 1.0 2 P12814 1
Vegfr2 mediated vascular permeability 0.3002859303396475 0.038587925622877 0.969218929081032 1.0 1.0 9 P31751 1
Activation of puma and translocation to mitochondria 0.3829181494661975 0.0380928155131892 0.969613679544334 1.0 1.0 2 Q13625 1
Tp53 regulates transcription of genes involved in cytochrome c release 0.3829181494661975 0.0380928155131892 0.969613679544334 1.0 1.0 2 Q13625 1
Tp53 regulates transcription of genes involved in g1 cell cycle arrest 0.3829181494661934 0.0380928155131873 0.9696136795443356 1.0 1.0 2 P24941 1
Rhot1 gtpase cycle 0.3772241992882605 0.0357417971142833 0.97148824255097 1.0 1.0 2 Q8IXI2 1
Nrage signals death through jnk 0.3286464197280836 0.0311099327982888 0.9751818682773176 1.0 1.0 5 Q9NY61 1
Erk mapk targets 0.297146775618719 0.030856683866053 0.9753838347261794 1.0 1.0 9 P30153,P30154 2
Mapk targets nuclear events mediated by map kinases 0.297146775618719 0.030856683866053 0.9753838347261794 1.0 1.0 9 P30153,P30154 2
Hcmv infection 0.2577480276950589 0.0276111145718902 0.977972316899606 1.0 1.0 49 P55735,Q9BW27,Q9BTX1,Q99567,P68371,Q8NFH4,P61978,P83916,Q9BVA1,P57740,Q12769 11
Regulation of tp53 activity through phosphorylation 0.2518859523896798 0.0261039098529651 0.9791744585148864 1.0 1.0 27 Q92804 1
Fbxw7 mutants and notch1 in cancer 0.2943060498220737 0.0200659810401658 0.9839907378757068 1.0 1.0 2 P63208 1
Synthesis of diphthamide eef2 0.2896797153025007 0.0198137017708684 0.9841919875970088 1.0 1.0 2 Q9H2P9 1
Rho gtpases activate paks 0.2865810135617511 0.0197914672976401 0.9842097246618468 1.0 1.0 10 O14974,P60660,P60953,Q14247,P21333,P35580,P35579,Q13177,P63000 9
Oncogene induced senescence 0.3611111111111129 0.0186819778477831 0.9850948053410082 1.0 1.0 4 Q9HCE1,P11802,P04637 3
Viral messenger rna synthesis 0.2551713645553244 0.0146027547954062 0.9883491014788296 1.0 1.0 35 P55735,P35269,Q9BW27,Q9BTX1,Q99567,Q8NFH4,O15514,P57740,Q12769 9
Displacement of dna glycosylase by apex1 0.3724120957863676 0.0109068070979149 0.9912977995426272 1.0 1.0 3 P13051 1
Scavenging by class a receptors 0.366965287243743 0.009266777629128 0.9926062870217358 1.0 1.0 3 Q5KU26 1
Diseases of mismatch repair mmr 0.3616945532217912 0.0078224083248476 0.9937586848204608 1.0 1.0 3 P43246,P52701 2
Signaling by erbb2 in cancer 0.344500136831644 0.0067819152170005 0.9945888560360764 1.0 1.0 4 Q16543 1
Signaling by erbb2 ecd mutants 0.344500136831644 0.0067819152170005 0.9945888560360764 1.0 1.0 4 Q16543 1
Signaling by egfr in cancer 0.344500136831644 0.0067819152170005 0.9945888560360764 1.0 1.0 4 Q16543 1
Constitutive signaling by egfrviii 0.344500136831644 0.0067819152170005 0.9945888560360764 1.0 1.0 4 Q16543 1
Constitutive signaling by ligand responsive egfr cancer variants 0.344500136831644 0.0067819152170005 0.9945888560360764 1.0 1.0 4 Q16543 1
Aquaporin mediated transport 0.3078987253801305 0.0065123855220706 0.9948039048667112 1.0 1.0 5 P10644 1
Processing of intronless pre mrnas 0.2630856642164647 0.0059300216669605 0.9952685549970564 1.0 1.0 15 Q5KU26,Q92797,P51003,O94992 4
Sumoylation of transcription factors 0.3481666073335753 0.0046974671931028 0.9962519772358523 1.0 1.0 3 Q12888,P04637 2
Metabolism of carbohydrates 0.2419499140123223 0.0044410866574158 0.996456537170965 1.0 1.0 95 P55735,Q8TB61,P08236,P06865,P13807,P57740,P16278,Q7LGA3,O43505,P10253,Q9UBX3,P30154,Q9BW27,P54802,P46926,O43252,Q9BTX1,P30153,Q8NFH4,P35573,Q12769 21
Oxidative stress induced senescence 0.2692416197244826 0.0029663136020704 0.9976332276452872 1.0 1.0 12 Q16539,Q15022,P45985,Q8IXK0,Q99496,Q9HCE1 6
Sensing of dna double strand breaks 0.3339266642933472 0.0021913856872009 0.998251528592828 1.0 1.0 3 P52292,P49959 2
Bile acid and bile salt metabolism 0.2886671418389111 0.0002129987706271 0.9998300515707316 1.0 1.0 6 Q9BZF3,P22059,P51659,Q96SU4,O14734 5
Synthesis of bile acids and bile salts 0.2886671418389111 0.0002129987706271 0.9998300515707316 1.0 1.0 6 Q9BZF3,P22059,P51659,Q96SU4,O14734 5