| Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size |
| Electron transport chain oxphos system in mitochondria 0.6749016542903782 4.379047509578452 1.191991460669506e-05 0.007055463994005 0.0012827896516614 51 Q9Y6M9,P00403,O43676,P00846,Q9UDW1,P03915,P24539,O14949,P21912,P56385,P13073,P12236,O75964,P20674,O96000,P12235,P14406,Q7KZN9,O75880 19 |
| Nonalcoholic fatty liver disease 0.644198449816478 3.848240968402114 0.000118969001895 0.0682323436010982 0.0032121630511652 47 O14949,Q9Y6M9,P20674,Q9P0J0,P00403,O43676,P21912,O96000,Q9UDW1,P14406,Q96GC9 11 |
| Drug induction of bile acid pathway 0.8637104662536774 3.4908313838910017 0.0004815200450603 0.2488063406068767 0.0083200380965448 2 P08183 1 |
| Aspirin and mirnas 0.8226279752200818 3.289057617686591 0.0010052344297031 0.4497648627859248 0.0121859030866052 2 O15439 1 |
| Vitamin d metabolism 0.8393315884891284 3.0464498789064014 0.0023156108165396 0.7476826901870205 0.0225487348364679 3 P04062 1 |
| Kennedy pathway from sphingolipids 0.8329508424506784 3.015995109940052 0.0025613739070604 0.782032202156296 0.0234070169352909 3 Q9UG56 1 |
| Zinc homeostasis 0.8261578604044242 2.983441468010397 0.0028502654681188 0.8164879809322253 0.0240287575769401 3 Q8TAD4,Q8NEW0 2 |
| Metabolism of spingolipids in er and golgi apparatus 0.8861337683523612 2.9618891055180105 0.0030575788516116 0.8378095635968169 0.0240287575769401 4 Q16880,O95470,Q06136 3 |
| Mrna protein and metabolite inducation pathway by cyclosporin a 0.7502445386371024 2.9202892171661614 0.0034970667509823 0.8751819615476184 0.0240287575769401 2 Q15758 1 |
| Phosphodiesterases in neuronal function 0.8108797286089073 2.9097245340982028 0.0036174743808559 0.8838271091021291 0.0241435930587462 3 O60658 1 |
| Sphingolipid metabolism integrated pathway 0.8951602866150468 2.8072478838349957 0.0049966775435641 0.9489763684622337 0.029680264608771 9 P27544,O95470,O15121,Q13510,Q96G23,Q06136,O15269 7 |
| Sphingolipid metabolism overview 0.8951602866150468 2.8072478838349957 0.0049966775435641 0.9489763684622337 0.029680264608771 9 P27544,O95470,O15121,Q13510,Q96G23,Q06136,O15269 7 |
| Sarscov2 and covid19 pathway 0.7859150137513526 2.7877519348508564 0.0053075167802199 0.9576192530037264 0.0309084800730453 3 Q8WTV0 1 |
| Mitochondrial complex i assembly model oxphos system 0.6099500427119927 2.6927386307506787 0.0070867800789076 0.9853678524377046 0.0386197006134965 27 O95168,Q9Y6M9,Q9P0J0,Q9BUB7,O43676,O96000,P03915,Q9NPL8,Q96CU9 9 |
| Mitochondrial complex iv assembly 0.7822530714627852 2.6757730579786614 0.0074557111338791 0.9882662322428968 0.0402608401229471 12 Q8N8Q8,Q9Y2R0,P20674,P00403,P14406,Q7KZN9,P13073 7 |
| Sphingolipid pathway 0.8559490393944922 2.6297278973153806 0.0085453234554477 0.993889423644183 0.0441384533263998 9 O95470,P04062,Q13510,Q96G23,Q06136,O15269 6 |
| Photodynamic therapyinduced nfe2l2 nrf2 survival signaling 0.8104404567699692 2.6144810684734985 0.0089363112767248 0.9951657480435308 0.0448625626398777 4 P09601,O15439,P07099 3 |
| Pkcgamma calcium signaling pathway in ataxia 0.6918813172481304 2.6096630655692863 0.009063143967652 0.9955196391071396 0.0448625626398777 2 Q15118 1 |
| Oxidative phosphorylation 0.5725885709304674 2.507850214027105 0.0121468145276597 0.9992964607185384 0.0575768434094582 30 O75964,O95168,Q9Y6M9,Q86Y39,O96000,P00846,P56385,P03915,P24539 9 |
| Kynurenine pathway and links to cell senescence 0.6706879686990525 2.4937523278150477 0.0126400707743168 0.9994770673284672 0.058270423176488 2 P04637 1 |
| Sphingolipid metabolism in senescence 0.7209192691618248 2.4788388252498548 0.0131810852917055 0.999622380586564 0.0597676691852909 14 P04062,O15121,Q13510,Q96G23,P16278,O15269 6 |
| Cholesterol biosynthesis with skeletal dysplasias 0.8324584796294239 2.4533270411748265 0.0141541588441653 0.9997898394684313 0.0627430623390614 5 Q15392,Q16850 2 |
| Transcription factor regulation in adipogenesis 0.6625366807955628 2.448716966809058 0.0143366055152156 0.9998117196223544 0.0630810642669488 2 Q16822 1 |
| Sarscov2 b117 variant antagonises innate immune activation 0.6596022171503069 2.4324419207846475 0.0149973965349081 0.9998735837915234 0.0644057765820356 2 O94826 1 |
| Mitochondrial complex iii assembly 0.7616621580890878 2.43065914883403 0.0150713854291295 0.9998791005191257 0.0644057765820356 11 O14949,Q9UDW1 2 |
| Statin inhibition of cholesterol production 0.819829872658709 2.3964061252133733 0.0165567339673557 0.9999506723206996 0.0689457555097704 5 P35610,Q8WTV0,Q14534 3 |
| Oxidation by cytochrome p450 0.8575614967416432 2.317562800987196 0.0204730938535366 0.9999953897579126 0.0783151631098145 6 O43169,Q16850,Q6UW02 3 |
| Degradation pathway of sphingolipids including diseases 0.8275313380519714 2.187466066852491 0.0287085177711041 0.9999999694049876 0.1027280696146739 6 P17900,P16278,P06280,P06865 4 |
| Influence of laminopathies on wnt signaling 0.7073537027209214 2.151208698407522 0.0314597307818194 0.9999999943258184 0.1098757258125823 11 P49354,O60725,O75844,P50402 4 |
| Glycosaminoglycan degradation 0.8184192362632696 2.1475923431037094 0.0317461542277686 0.9999999952400436 0.1098757258125823 6 P54802,P16278,P15586,P06865 4 |
| Acquired partial lipodystrophy barraquersimons syndrome 0.7629533386403884 2.1350729467588003 0.0327550520425492 0.999999997437504 0.112465323198117 5 O60725 1 |
| Cholesterol metabolism with bloch and kandutschrussell pathways 0.579193893129549 2.119590256234854 0.0340406149055441 0.999999998837035 0.1155435728793897 21 Q15800,P35610,Q15392,Q9BWD1,Q14739,Q16850,Q14534 7 |
| Overlap between signal transduction pathways contributing to lmna laminopathies 0.6084580320095007 1.9610868224886593 0.0498688956580062 0.9999999999999364 0.1542818959419567 16 O60725,P49354,O75844,P50402,P55209,P42167 6 |
| Ferroptosis 0.5187530903552273 1.8710989326689644 0.0613313695155266 1.0 0.1812479278220041 24 P16435,P48507,P37268,Q9UKU0,Q9Y277,Q15758,Q15043,Q96QD8,P09601,P45880 10 |
| Aryl hydrocarbon receptor pathway wp2873 0.6557786884997696 1.8547492579351712 0.0636320411005046 1.0 0.1861942483433487 4 Q16543,O00170 2 |
| Cholesterol biosynthesis pathway 0.6454640007595358 1.821621079840411 0.0685125001661879 1.0 0.1919642693335643 11 Q15800,Q14534,Q16850 3 |
| Type i collagen synthesis in the context of osteogenesis imperfecta 0.6211210841362862 1.8080193740196284 0.070603485302823 1.0 0.1959741601396115 12 O75718,P07237,O15460,P13674,Q96AY3,Q32P28 6 |
| Riboflavin and coq disorders 0.6220306558690027 1.6799735860726863 0.0929624550550505 1.0 0.2408219446354486 4 Q8NFF5,Q16134 2 |
| Gpr40 pathway 0.5252689925008084 1.6517810786959986 0.0985791872534092 1.0 0.2534893386516236 2 P29992 1 |
| Intracellular trafficking proteins involved in cmt neuropathy 0.6017295539769644 1.5818968222571 0.113673126507918 1.0 0.2722654723617069 11 Q9NR77,P07196,P50570,Q8TB36,O95140,Q9UI14,P20337 7 |
| Familial hyperlipidemia type 4 0.507336159113136 1.5425349107443809 0.1229436612216043 1.0 0.2909503377116852 2 Q07954 1 |
| Cellular proteostasis 0.6335947328035112 1.5109611291539966 0.1307983547071747 1.0 0.3034930574064913 5 P61758,O15212 2 |
| Metapathway biotransformation phase i and ii 0.4844089879038687 1.461948183068691 0.1437554098654725 1.0 0.3205365151672359 21 Q86UY6,Q16850,Q6UW02,Q7LGA3 4 |
| Allograft rejection 0.6144980824974439 1.4478841874142665 0.1476494426652594 1.0 0.3260363157738443 9 P08183,Q9BY49,P08670,P10321 4 |
| Striated muscle contraction pathway 0.6173232440176828 1.4298399228930383 0.152762967918735 1.0 0.333607363763708 5 O43707,P08670 2 |
| Tyrobp causal network in microglia 0.559851330363645 1.3506874520559031 0.1767955734883588 1.0 0.3697766572256519 4 O15439,Q15418 2 |
| Endothelin pathways 0.6063899650109031 1.3201468008352473 0.1867860097412881 1.0 0.374967712507751 8 P00403,P42892 2 |
| Familial partial lipodystrophy fpld 0.6214425224004769 1.3161755888433215 0.1881151150291411 1.0 0.374967712507751 7 O75844,O60725 2 |
| Alzheimers disease and mirna effects 0.3521322845386165 1.3050172472253143 0.1918869749606615 1.0 0.3782984978456001 82 Q92542,Q9NQC3,P28072,P21796,P12236,P16615,P28070,P49721,O95197,Q9Y277,P12235,P49720,Q96GC9,P45880 14 |
| Vitamin d receptor pathway 0.5511939507804425 1.2989539279885145 0.193959740771703 1.0 0.3782984978456001 11 P08183,Q92783,Q96KA5,Q5VV42,P20020 5 |
| Serotonin and anxiety 0.5084801043704936 1.298125601538205 0.1942441781867139 1.0 0.3782984978456001 3 Q06787,Q08209 2 |
| Genes related to primary cilium development based on crispr 0.5791769131497021 1.2634728977037144 0.2064192806412494 1.0 0.3955259764545232 9 A0AVF1,Q10713 2 |
| Fluoropyrimidine activity 0.5186326464572932 1.255634390189572 0.2092485568036415 1.0 0.3996580152455404 13 P31350,P00374 2 |
| Phase i biotransformations non p450 0.4778013339125811 1.1205404934520535 0.2624835068391853 1.0 0.4728502711697568 3 P38571 1 |
| Alzheimers disease 0.3377218668047448 1.1113133782402234 0.2664334828644532 1.0 0.478131386167629 80 Q92542,Q9NQC3,P28072,P21796,P12236,P16615,P28070,P49721,O95197,Q9Y277,P12235,P49720,P45880 13 |
| Ccl18 signaling pathway 0.5292549020178013 1.0829665833455513 0.2788232557769747 1.0 0.4958712991961767 10 P07196,Q96GC9,P00403,P08670 4 |
| Pregnane x receptor pathway 0.5458872224881678 1.0694154056319964 0.2848825285536756 1.0 0.5013885573934488 5 P08183,O15439 2 |
| Hippoyap signaling pathway 0.4287577437235093 1.05446984744712 0.2916678584212673 1.0 0.5080665920886591 2 P27348 1 |
| Mitochondrial long chain fatty acid betaoxidation 0.4776983494297315 1.0483053380304934 0.2944979510356984 1.0 0.5100051980035127 14 Q16836,Q9BY49,P50416,P23786 4 |
| 1q211 copy number variation syndrome 0.5276593688571024 0.9922147899575634 0.3210927592670574 1.0 0.5496515821459138 9 Q9NPH0 1 |
| Spinal cord injury 0.4169816176391986 0.974557095345949 0.3297800046912735 1.0 0.5580892387083091 21 P04083,P62942,Q9NQC3,P08670 4 |
| Mevalonate arm of cholesterol biosynthesis pathway 0.5086489083569176 0.8922012446792528 0.3722850751695794 1.0 0.6042003678981699 9 P35610,Q9BWD1 2 |
| Nocgmppkg mediated neuroprotection 0.5419094439704747 0.864679046046426 0.3872149734403471 1.0 0.6202537139579295 6 P30536 1 |
| Nephrotic syndrome 0.4485814602096881 0.8002872649995987 0.4235443798045926 1.0 0.6467490015525141 12 O75844 1 |
| 7oxoc and 7betahc pathways 0.4906461241905097 0.7979888872058543 0.4248769390028046 1.0 0.6471202609427332 9 O15118,O14734 2 |
| Apoptosis modulation by hsp70 0.4168297455968631 0.7682199473570769 0.442356524648372 1.0 0.6685999380181501 3 P49327,Q13546 2 |
| Mecp2 and associated rett syndrome 0.4103021310718329 0.7054591043443308 0.4805245734482608 1.0 0.7065138530402647 16 P35637,P52597 2 |
| Development of ureteric collection system 0.4054142204827112 0.703335725160162 0.4818465519352699 1.0 0.7067082761717293 3 P35222,P05556 2 |
| Copper homeostasis 0.4681185224022923 0.6813554652344138 0.4956465952253148 1.0 0.720240783808637 9 P35670,O75880,P25054 3 |
| Amyotrophic lateral sclerosis als 0.4505041968559176 0.6558715994284964 0.5119067430481565 1.0 0.7309295964007914 10 P07196,O96008,P07197,Q08209,Q9BUN8 5 |
| Cohesin complex cornelia de lange syndrome 0.4036415000448028 0.6281573393221234 0.5299008737362194 1.0 0.7458794289083278 15 P30153,P53350,Q9Y6X3,P30154 4 |
| Camkk2 pathway 0.4272063887744358 0.600063426818021 0.5484639655519996 1.0 0.7628996376244822 11 P09601,Q14012 2 |
| Progeriaassociated lipodystrophy 0.4364164869986095 0.5816515644065674 0.5608014027792283 1.0 0.7657839844847393 10 O75844,O60725 2 |
| Regulation of wnt bcatenin signaling by small molecule compounds 0.436518428186606 0.5255247877523087 0.5992184263252271 1.0 0.8029436292444848 5 P25054 1 |
| Tcell receptor tcr signaling pathway 0.3780610368291539 0.504819849083752 0.6136853732052401 1.0 0.8125669483356172 16 P46108 1 |
| Mitochondrial immune response to sarscov2 0.4189832287654274 0.4916642696329865 0.6229567010733237 1.0 0.8136581488972586 10 Q9Y375,Q9Y6M9,P35232,O94826,Q9Y276,Q9BQ95,Q99623 7 |
| Fatty acid betaoxidation 0.3461381625713276 0.4701828271139341 0.6382244022272552 1.0 0.8253081656399128 21 P35610,P23786,Q9UKU0,P50416,Q16836 5 |
| Folate metabolism 0.3754604302357983 0.4592222500749308 0.646074574112053 1.0 0.8253081656399128 15 P00374 1 |
| Physicochemical features and toxicityassociated pathways 0.3693547688012835 0.4523035586920078 0.6510503126024263 1.0 0.8265736653480478 16 P07196,P07197,Q14012 3 |
| Vitamin dsensitive calcium signaling in depression 0.4181023983748101 0.4395242508119366 0.6602817141276949 1.0 0.8338590655748161 5 Q8NB78 1 |
| Ppar signaling pathway 0.3635395941568242 0.4177494255362973 0.676130331275965 1.0 0.8490069909061507 16 O14975,P23786,O95864,Q9UKU0,P50416,Q15067 6 |
| Leptininsulin signaling overlap 0.3221388979458808 0.4097196985525844 0.6820115782193676 1.0 0.8528734262364303 2 O14654 1 |
| Inhibition of exosome biogenesis and secretion by manumycin a in crpc cells 0.4050925811220539 0.3705884781745903 0.7109440650468057 1.0 0.8664078654499645 9 P20339,P61020,O14964,P31943 4 |
| Vitamin a and carotenoid metabolism 0.3998729695838398 0.3575405206882195 0.7206871969934847 1.0 0.8664078654499645 5 Q8WTV0 1 |
| Ketogenesis and ketolysis 0.427950919685099 0.3496826283825031 0.7265768921455509 1.0 0.8672004309947501 6 P53985,P23786 2 |
| Calcium regulation in cardiac cells 0.3057800903259181 0.341730801010207 0.7325534902168869 1.0 0.8672004309947501 29 P62258,Q9UBI6,Q14012,P08133,P63104,P16615,P62942,P09471,P20020 9 |
| Extracellular vesicles in the crosstalk of cardiac cells 0.3222439660795774 0.2655116888690388 0.7906153064856034 1.0 0.8965338113371989 3 P04792,Q96HC4 2 |
| Thiamine metabolic pathways 0.4063153613889527 0.2629874195790356 0.7925602756393559 1.0 0.8965338113371989 6 Q9HC21 1 |
| Mammary gland development pathway pregnancy and lactation stage 3 of 4 0.3772845953002746 0.261457546973222 0.7937396837469937 1.0 0.8965338113371989 5 P06753,P18031,P61201,P04150 4 |
| Envelope proteins and their potential roles in edmd physiopathology 0.3309897205543299 0.2575033915596414 0.7967901974759664 1.0 0.8965338113371989 17 Q14739,Q9BTV4,P42167,P50402 4 |
| Glycosylation and related congenital defects 0.3886612243969626 0.2573365966710219 0.7969189434108435 1.0 0.8965338113371989 8 Q9BT22 1 |
| Adipogenesis 0.340652275220115 0.2446283490893618 0.8067442114608272 1.0 0.900152583485593 14 O75844 1 |
| Proteasome degradation 0.2729045512429499 0.2127765776437949 0.8315012337398116 1.0 0.907925979487956 42 P20618,P28072,P28070,P49721,P04439,P49720,P10321 7 |
| Egfegfr signaling pathway 0.2695171081918167 0.1835486948291419 0.8543675147478822 1.0 0.9260844959128504 42 P46108,Q9P0J0 2 |
| G protein signaling pathways 0.3127062310527626 0.1813482270389791 0.8560942538219694 1.0 0.9262659139713112 18 Q92667,Q9UBI6,P09471,O43823,Q08209,P10644,O60658 7 |
| Ethanol effects on histone modifications 0.3494423380830855 0.1671641963317179 0.8672408551652881 1.0 0.9349202685447934 10 P00374 1 |
| Omega3 omega6 fatty acid synthesis 0.3797396024053636 0.1649088064076716 0.8690157607941611 1.0 0.9351365252024124 6 P33121,O95864,Q15067 3 |
| Omega9 fatty acid synthesis 0.3466057441253299 0.1434140947476508 0.8859631520406814 1.0 0.95164938935292 5 P33121,O95864,P49327,O60488 4 |
| Wnt signaling pathway and pluripotency 0.3132419038176399 0.1274532309807499 0.8985816874888992 1.0 0.9589770349576596 15 P30153,P30154 2 |
| Tryptophan metabolism 0.3069675240745644 0.0987909642322193 0.9213042428956664 1.0 0.98074322630829 15 Q15392,P35610,P51648 3 |
| Prostaglandin synthesis and regulation 0.345998468296743 0.074225954526715 0.940830594085428 1.0 0.9997376974718144 7 P04083,O15439,P09525,P08133 4 |
| Vitamin b12 disorders 0.2992873767319642 0.0684335173350635 0.9454405413844472 1.0 1.0 4 Q9H3L0 1 |
| Interactions between loxl4 and oxidative stress pathway 0.2926590538336086 0.047213981305523 0.9623426844788804 1.0 1.0 4 Q16543,Q9BQ95,Q96EB6 3 |
| Pparalpha pathway 0.3349376169407438 0.0408313610003069 0.967430337736358 1.0 1.0 7 P50416,P11802,P23786 3 |
| Preimplantation embryo 0.3307438529753325 0.0288334020110924 0.9769974609953278 1.0 1.0 7 Q99729,Q92945 2 |
| Ciliopathies 0.2916529928251551 0.0242799934156692 0.9806292713683986 1.0 1.0 14 Q10713,Q9UBB4 2 |
| Ciliary landscape 0.2523774302462688 0.0224404288759054 0.9820966308831592 1.0 1.0 97 Q96PK6,P25054,P11234,Q14566,P60660,P06280,P07196,P07197,A0AVF1,O43805,P16278,P55081,O15173,P10619,Q9UPT5,P08670 16 |
| Bdnftrkb signaling 0.3233180927498364 0.0085098922889725 0.9932101702799156 1.0 1.0 7 Q15334,Q02750,P42345,P19174,P62993,Q15418 6 |
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