term
stringlengths 2
121
| overlap
int64 6
281
| setsize
int64 7
499
| score
float64 1.96
10.6
| pval
float64 0
0.05
| edge
stringlengths 41
1.97k
| type
stringclasses 5
values | subtype
stringclasses 24
values | subtype_key
stringclasses 24
values | edge_idxs
stringlengths 11
1.17k
| ann_idxs
stringlengths 19
2.31k
| ann_vals
stringlengths 124
9.94k
| sig_size
int64 2.2k
3.73k
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Hallucinations
| 15
| 52
| 2.679227
| 0.007379
|
Q6DKK2,P07602,O96008,P19022,O00754,Q9NZJ7,P05067,P35637,P42858,O75503,P04062,Q9BQE5,O76024,P50897,O60313
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
97,34,308,346,208,222,83,421,265,24,210,27,364,29,209
|
2761,1635,208,2814,209,688,24,364,308,210,83,34,3207,2245,633,1003,346,446,1391,736,421,1900,533,265,1484,2170,29,2080,1398,581,2082,1745,2675,1919,1411,1923,945,2931,97,2484,3133,1165,2199,1608,3304,27,1444,222,1285,854,1373,3299
|
-0.7101048204413503,-0.032043988936474706,1.2109881782657737,-0.7580513366787757,1.2109881782657737,0.5019846818620551,3.8514472696790003,0.8099100211162025,0.9217383587835264,1.2109881782657737,2.3477816274627044,3.297852942116772,-1.3109065691871442,-0.33934491131952355,0.5412829355853829,0.30182221516229196,0.8473984012280706,0.6961379107980552,0.09521457913715693,0.46244619964697814,0.7342826270023676,-0.1619123131620609,0.619171741197861,1.031696165695717,0.05307774962454346,-0.29451413807445087,3.679843814797915,-0.25000179333226685,0.09521457913715693,0.580344223839915,-0.25000179333226685,-0.07503752950409251,-0.6153160198205229,-0.1619123131620609,0.09521457913715693,-0.1619123131620609,0.342355682402477,-0.8550813717441338,2.0730777150539357,-0.4758002447614249,-1.1044492003404638,0.2199786322467286,-0.29451413807445087,0.010659648604851009,-1.7421936575233459,3.7292869846617753,0.09521457913715693,1.2109881782657737,0.1786609951774037,0.42266415546022,0.13707430384263497,-1.686951965968084
| 3,367
|
Glycoprotein biosynthetic process
| 21
| 50
| 2.63343
| 0.008453
|
Q86SF2,P35222,P35610,Q6ZXV5,O15118,Q99805,P46977,Q9H0U3,Q8WVQ1,O60502,Q10471,Q16706,O60476,Q92542,Q10472,Q08379,Q2TAA5,Q7LGA3,Q8TCJ2,O75352,O43505
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
256,531,532,297,46,184,422,322,318,64,312,335,81,218,452,212,350,374,661,363,122
|
1548,2235,46,2308,122,81,64,1642,2446,1812,3325,363,2706,1983,919,531,532,2721,422,2544,2180,872,2408,212,312,452,1327,1329,335,350,297,374,1853,256,1776,661,318,218,3071,1606,184,1787,322,674,1106,1112,1187,2144,905,1121
|
0.010659648604851009,-0.33934491131952355,2.8943684331092254,-0.38449929077288447,1.7869199137107399,2.377641277448686,2.640766626646635,-0.032043988936474706,-0.4758002447614249,-0.11832544439901459,-1.9101855426565795,0.8099100211162025,-0.6625285072121776,-0.2058028271615026,0.342355682402477,0.619171741197861,0.619171741197861,-0.6625285072121776,0.7342826270023676,-0.5219578544209845,-0.29451413807445087,0.38263514328382814,-0.42998258634220327,1.2109881782657737,0.9217383587835264,0.6961379107980552,0.13707430384263497,0.13707430384263497,0.884673610049861,0.8473984012280706,0.9585953053509725,0.8099100211162025,-0.11832544439901459,1.0679451413858796,-0.07503752950409251,0.5412829355853829,0.9217383587835264,1.2109881782657737,-1.0035370570387363,0.010659648604851009,1.3510176219205223,-0.07503752950409251,0.9217383587835264,0.5412829355853829,0.26103110464403734,0.26103110464403734,0.2199786322467286,-0.25000179333226685,0.38263514328382814,0.26103110464403734
| 3,367
|
Azurophil granule membrane
| 11
| 22
| 2.624472
| 0.008678
|
P42785,P07602,O00462,Q07065,O15260,Q9NZJ7,P10253,P27105,Q92542,P11279,P13473
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
2,34,66,225,14,222,143,114,218,150,30
|
66,14,2313,688,1382,34,143,150,30,114,2721,2,2598,225,821,883,218,1433,2804,322,222,1708
|
2.5831453876103505,4.34342738654226,-0.38449929077288447,0.5019846818620551,0.09521457913715693,3.297852942116772,1.5892312826899408,1.5557134250916398,3.6549956055948876,1.8515558846925475,-0.6625285072121776,6.292167445838333,-0.5684611504154431,1.1755156156311373,0.42266415546022,0.38263514328382814,1.2109881782657737,0.09521457913715693,-0.7101048204413503,0.9217383587835264,1.2109881782657737,-0.032043988936474706
| 3,367
|
Glycerophospholipid metabolic process
| 16
| 59
| 2.607365
| 0.009124
|
Q92604,Q8NCC3,Q10713,Q9BZF1,Q8N9F7,Q8WTV0,Q96N66,P42356,Q96Q15,Q9H490,Q96S52,P35790,O95674,Q86TV6,Q8IY17,Q9UG56
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
259,0,287,192,403,5,133,198,98,235,380,48,330,182,316,361
|
3200,570,1975,624,2702,1812,1129,330,3230,2956,1730,1390,3189,3247,48,932,198,1485,738,1829,1571,287,1073,1663,426,182,1774,316,659,403,0,883,2202,5,3069,758,259,1601,718,2122,133,98,380,3321,975,2750,2032,1099,1951,1359,192,1868,235,2696,1706,561,361,1964,566
|
-1.3109065691871442,0.580344223839915,-0.2058028271615026,0.5412829355853829,-0.6625285072121776,-0.11832544439901459,0.2199786322467286,0.884673610049861,-1.3634818904670298,-0.9041772408267448,-0.07503752950409251,0.09521457913715693,-1.2587149217723634,-1.416440179685344,2.8943684331092254,0.342355682402477,1.2813706494606423,0.05307774962454346,0.46244619964697814,-0.11832544439901459,0.010659648604851009,0.995247055805408,0.26103110464403734,-0.032043988936474706,0.7342826270023676,1.3510176219205223,-0.07503752950409251,0.9217383587835264,0.5412829355853829,0.7722057037721174,6.753408671655479,0.38263514328382814,-0.29451413807445087,5.895453047698817,-1.0035370570387363,0.46244619964697814,1.0679451413858796,0.010659648604851009,0.5019846818620551,-0.25000179333226685,1.6557714498436458,2.0730777150539357,0.8099100211162025,-1.853811091154964,0.342355682402477,-0.6625285072121776,-0.2058028271615026,0.26103110464403734,-0.1619123131620609,0.13707430384263497,1.3162849902600815,-0.11832544439901459,1.1398524773123389,-0.6153160198205229,-0.032043988936474706,0.619171741197861,0.8473984012280706,-0.1619123131620609,0.619171741197861
| 3,367
|
Glycosphingolipid metabolism
| 9
| 15
| 2.603686
| 0.009223
|
P07602,P06280,P16278,P10619,P17900,Q9NZJ7,P07686,P06865,Q13510
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
34,67,68,106,107,222,119,84,90
|
989,2814,210,67,84,34,119,106,633,68,107,90,2625,561,222
|
0.30182221516229196,-0.7580513366787757,1.2109881782657737,2.554155818031785,2.3177928418789855,3.297852942116772,1.8193146884450921,1.9473741733456051,0.5412829355853829,2.554155818031785,1.9155840365977252,2.227038925427992,-0.5684611504154431,0.619171741197861,1.2109881782657737
| 3,367
|
Exopeptidase activity
| 13
| 31
| 2.586232
| 0.009703
|
Q9H3G5,P42785,P55786,Q9UIQ6,P10619,Q92820,Q9NZ08,Q9HB40,O75976,O75844,O14773,Q96DE0,Q9NQH7
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
1,2,162,103,106,139,148,16,175,113,20,219,61
|
20,113,175,239,3005,106,2657,2456,2326,1900,2,2597,869,162,3264,1241,3194,2117,139,1780,219,2124,2804,1,1954,16,61,3106,2573,148,103
|
3.9953969719732,1.8515558846925475,1.3855706609057188,1.103996441331084,-0.9536627270282968,1.9473741733456051,-0.6153160198205229,-0.4758002447614249,-0.38449929077288447,-0.1619123131620609,6.292167445838333,-0.5684611504154431,0.38263514328382814,1.4541462370669627,-1.4697807385854578,0.1786609951774037,-1.2587149217723634,-0.25000179333226685,1.6225833456176855,-0.07503752950409251,1.2109881782657737,-0.25000179333226685,-0.7101048204413503,6.653184264123767,-0.1619123131620609,4.320727255133443,2.6979179668449453,-1.053799466605388,-0.5219578544209845,1.5892312826899408,2.0105143282367153
| 3,367
|
Abnormal vascular physiology
| 13
| 58
| 2.569695
| 0.010179
|
Q14108,Q71SY5,Q5T2R2,O95235,P06280,Q9Y4P3,Q14739,Q9NZ08,O75844,Q96HP0,P05067,Q8IZA0,P04062
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
32,33,255,284,67,302,76,148,113,272,83,152,210
|
570,3034,1979,1642,1644,3229,113,284,2866,693,294,1816,210,1555,83,67,1386,1003,2249,1559,1989,2774,3151,531,2254,1738,1484,1740,2079,641,2177,644,1405,872,3159,1240,32,1500,76,3284,255,1419,1510,2019,33,152,828,1349,272,2695,148,615,2225,514,1115,1460,302,3299
|
0.580344223839915,-1.0035370570387363,-0.2058028271615026,-0.032043988936474706,-0.032043988936474706,-1.3634818904670298,1.8515558846925475,0.995247055805408,-0.8063746087452964,0.5019846818620551,0.9585953053509725,-0.11832544439901459,1.2109881782657737,0.010659648604851009,2.3477816274627044,2.554155818031785,0.09521457913715693,0.30182221516229196,-0.33934491131952355,0.010659648604851009,-0.2058028271615026,-0.7101048204413503,-1.1554855115344582,0.619171741197861,-0.33934491131952355,-0.07503752950409251,0.05307774962454346,-0.07503752950409251,-0.25000179333226685,0.5412829355853829,-0.29451413807445087,0.5412829355853829,0.09521457913715693,0.38263514328382814,-1.1554855115344582,0.1786609951774037,3.5799366048175845,0.05307774962454346,2.4369781355796594,-1.5776059098511652,1.0679451413858796,0.09521457913715693,0.05307774962454346,-0.2058028271615026,3.4530829773454683,1.5557134250916398,0.42266415546022,0.13707430384263497,1.031696165695717,-0.6153160198205229,1.5892312826899408,0.580344223839915,-0.29451413807445087,0.657768615715268,0.26103110464403734,0.09521457913715693,0.9585953053509725,-1.686951965968084
| 3,367
|
Endocytic vesicle membrane
| 11
| 40
| 2.540473
| 0.01107
|
Q14108,P02786,Q8WTV0,P20645,Q12846,Q9Y487,P13473,Q93050,P11279,Q5KU26,P11717
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
32,239,5,44,144,186,30,62,150,120,156
|
476,1295,2648,631,918,294,239,527,1307,150,156,30,2388,44,2774,2078,1907,1142,2676,2543,1011,2087,1232,1571,1324,144,491,2184,32,1929,2737,120,2108,5,62,761,975,2212,2858,186
|
0.657768615715268,0.13707430384263497,-0.6153160198205229,0.5412829355853829,0.342355682402477,0.9585953053509725,1.103996441331084,0.619171741197861,0.13707430384263497,1.5557134250916398,1.522027904662708,3.6549956055948876,-0.42998258634220327,2.976917059317765,-0.7101048204413503,-0.25000179333226685,-0.1619123131620609,0.2199786322467286,-0.6153160198205229,-0.5219578544209845,0.30182221516229196,-0.25000179333226685,0.1786609951774037,0.010659648604851009,0.13707430384263497,1.5892312826899408,0.657768615715268,-0.29451413807445087,3.5799366048175845,-0.1619123131620609,-0.6625285072121776,1.8193146884450921,-0.25000179333226685,5.895453047698817,2.669400494336479,0.46244619964697814,0.342355682402477,-0.29451413807445087,-0.7580513366787757,1.3510176219205223
| 3,367
|
Hydrolase activity acting on glycosyl bonds
| 15
| 33
| 2.530555
| 0.011388
|
O60502,P54802,O00462,P06280,P16278,P17900,O60476,P10253,P07686,P06865,P13051,O75503,O00754,Q9BTY2,P04066
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
64,65,66,67,68,107,81,143,119,84,189,24,208,153,94
|
66,208,3259,81,64,24,210,94,67,84,119,143,2768,189,68,107,2772,926,2587,1135,65,2344,3015,1327,2096,335,2558,1592,3334,153,1536,3107,1882
|
2.5831453876103505,1.2109881782657737,-1.4697807385854578,2.377641277448686,2.640766626646635,3.8514472696790003,1.2109881782657737,2.1041468018137355,2.554155818031785,2.3177928418789855,1.8193146884450921,1.5892312826899408,-0.7101048204413503,1.3162849902600815,2.554155818031785,1.9155840365977252,-0.7101048204413503,0.342355682402477,-0.5684611504154431,0.2199786322467286,2.640766626646635,-0.38449929077288447,-0.9536627270282968,0.13707430384263497,-0.25000179333226685,0.884673610049861,-0.5219578544209845,0.010659648604851009,-2.024062737158297,1.5557134250916398,0.05307774962454346,-1.053799466605388,-0.11832544439901459
| 3,367
|
Receptor mediated endocytosis
| 9
| 57
| 2.526466
| 0.011522
|
Q14108,P41440,Q5VW38,P20645,P05067,P02786,O00560,P50897,P11717
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
32,102,9,44,83,239,188,29,156
|
2762,476,188,2511,1891,688,238,631,918,239,83,2064,2159,1897,795,156,2323,2388,44,2073,927,2328,102,1902,1009,2078,29,1142,1403,2968,2546,1832,2087,1232,2404,1837,1324,1577,3056,1663,32,1578,3098,3266,2737,9,2198,2616,1167,761,1702,3256,3143,986,2051,1888,2579
|
-0.7101048204413503,0.657768615715268,1.3162849902600815,-0.5219578544209845,-0.1619123131620609,0.5019846818620551,1.103996441331084,0.5412829355853829,0.342355682402477,1.103996441331084,2.3477816274627044,-0.25000179333226685,-0.29451413807445087,-0.1619123131620609,0.42266415546022,1.522027904662708,-0.38449929077288447,-0.42998258634220327,2.976917059317765,-0.25000179333226685,0.342355682402477,-0.38449929077288447,2.0105143282367153,-0.1619123131620609,0.30182221516229196,-0.25000179333226685,3.679843814797915,0.2199786322467286,0.09521457913715693,-0.9041772408267448,-0.5219578544209845,-0.11832544439901459,-0.25000179333226685,0.1786609951774037,-0.42998258634220327,-0.11832544439901459,0.13707430384263497,0.010659648604851009,-1.0035370570387363,-0.032043988936474706,3.5799366048175845,0.010659648604851009,-1.053799466605388,-1.4697807385854578,-0.6625285072121776,4.82614995544459,-0.29451413807445087,-0.5684611504154431,0.2199786322467286,0.46244619964697814,-0.032043988936474706,-1.416440179685344,-1.1044492003404638,0.342355682402477,-0.2058028271615026,-0.11832544439901459,-0.5219578544209845
| 3,367
|
Sterol metabolic process
| 12
| 40
| 2.511854
| 0.01201
|
P61916,Q8WTV0,Q15800,Q14739,Q14849,O15118,P05067,P34913,Q9BQE5,Q15392,Q16850,Q9UBM7
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
99,5,105,76,49,46,83,88,27,28,95,63
|
46,2315,2241,210,83,2818,3043,694,2872,88,532,367,2876,2593,935,130,2336,2727,1401,99,2007,3355,2406,1496,2927,1151,76,49,3266,589,3214,28,2098,105,95,5,27,63,1455,2300
|
2.8943684331092254,-0.38449929077288447,-0.33934491131952355,1.2109881782657737,2.3477816274627044,-0.7580513366787757,-1.0035370570387363,0.5019846818620551,-0.8063746087452964,2.2574227850195774,0.619171741197861,0.8099100211162025,-0.8063746087452964,-0.5684611504154431,0.342355682402477,1.6887973998936312,-0.38449929077288447,-0.6625285072121776,0.09521457913715693,2.041867375489916,-0.2058028271615026,-2.800617632892994,-0.42998258634220327,0.05307774962454346,-0.8550813717441338,0.2199786322467286,2.4369781355796594,2.8943684331092254,-1.4697807385854578,0.580344223839915,-1.3109065691871442,3.7046073923024947,-0.25000179333226685,1.9790170949571289,2.1041468018137355,5.895453047698817,3.7292869846617753,2.669400494336479,0.09521457913715693,-0.33934491131952355
| 3,367
|
Dysmetria
| 11
| 52
| 2.511814
| 0.012011
|
Q6DKK2,Q10713,P42356,P41440,O14773,Q9NPL8,Q8IV08,P07384,O75503,O60313,Q12768
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
97,287,198,102,20,87,151,240,24,209,127
|
2233,20,1202,1293,1979,209,2447,1813,24,240,862,1218,1315,2254,393,102,198,1995,2178,1405,1837,287,2788,127,3265,945,3284,542,2482,97,1772,1338,151,1165,2282,659,2981,1094,1437,2132,1790,87,1366,3107,2143,774,2640,514,3270,1195,302,1289
|
-0.33934491131952355,3.9953969719732,0.1786609951774037,0.13707430384263497,-0.2058028271615026,1.2109881782657737,-0.4758002447614249,-0.11832544439901459,3.8514472696790003,1.103996441331084,0.38263514328382814,0.1786609951774037,0.13707430384263497,-0.33934491131952355,0.7722057037721174,2.0105143282367153,1.2813706494606423,-0.2058028271615026,-0.29451413807445087,0.09521457913715693,-0.11832544439901459,0.995247055805408,-0.7101048204413503,1.7216629695769743,-1.4697807385854578,0.342355682402477,-1.5776059098511652,0.619171741197861,-0.4758002447614249,2.0730777150539357,-0.07503752950409251,0.13707430384263497,1.5557134250916398,0.2199786322467286,-0.33934491131952355,0.5412829355853829,-0.9041772408267448,0.26103110464403734,0.09521457913715693,-0.25000179333226685,-0.07503752950409251,2.3177928418789855,0.13707430384263497,-1.053799466605388,-0.25000179333226685,0.46244619964697814,-0.5684611504154431,0.657768615715268,-1.4697807385854578,0.2199786322467286,0.9585953053509725,0.1786609951774037
| 3,367
|
Sphingolipid biosynthetic process
| 6
| 16
| 2.50467
| 0.012257
|
O95470,Q96G23,Q06136,Q99805,Q13510,P04062
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
160,38,11,184,90,210
|
282,1204,160,210,924,1899,1410,11,1496,90,1335,38,184,561,851,1708
|
0.995247055805408,0.1786609951774037,1.4881728202808266,1.2109881782657737,0.342355682402477,-0.1619123131620609,0.09521457913715693,4.783524978682848,0.05307774962454346,2.227038925427992,0.13707430384263497,3.192469446149936,1.3510176219205223,0.619171741197861,0.42266415546022,-0.032043988936474706
| 3,367
|
Secondary alcohol metabolic process
| 12
| 43
| 2.499879
| 0.012424
|
P61916,Q8WTV0,Q15800,Q14739,Q14849,O15118,P05067,P34913,Q9BQE5,Q15392,Q16850,Q9UBM7
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
99,5,105,76,49,46,83,88,27,28,95,63
|
46,1640,3329,2315,2241,210,83,2818,3043,694,2872,88,532,367,2593,935,3154,130,2880,2336,2727,1401,99,2007,3355,2406,1496,2927,1151,76,49,3266,589,3214,28,2098,105,95,5,1864,27,63,1455
|
2.8943684331092254,-0.032043988936474706,-1.9669363010637892,-0.38449929077288447,-0.33934491131952355,1.2109881782657737,2.3477816274627044,-0.7580513366787757,-1.0035370570387363,0.5019846818620551,-0.8063746087452964,2.2574227850195774,0.619171741197861,0.8099100211162025,-0.5684611504154431,0.342355682402477,-1.1554855115344582,1.6887973998936312,-0.8063746087452964,-0.38449929077288447,-0.6625285072121776,0.09521457913715693,2.041867375489916,-0.2058028271615026,-2.800617632892994,-0.42998258634220327,0.05307774962454346,-0.8550813717441338,0.2199786322467286,2.4369781355796594,2.8943684331092254,-1.4697807385854578,0.580344223839915,-1.3109065691871442,3.7046073923024947,-0.25000179333226685,1.9790170949571289,2.1041468018137355,5.895453047698817,-0.11832544439901459,3.7292869846617753,2.669400494336479,0.09521457913715693
| 3,367
|
Organophosphate ester transmembrane transporter activity
| 6
| 11
| 2.492749
| 0.012676
|
P41440,Q8TB61,Q9BSK2,Q99808,Q9H2D1,Q9HC21
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
102,270,274,158,123,360
|
1639,1001,1310,419,102,2019,270,158,274,123,360
|
-0.032043988936474706,0.30182221516229196,0.13707430384263497,0.7342826270023676,2.0105143282367153,-0.2058028271615026,1.031696165695717,1.522027904662708,1.031696165695717,1.7869199137107399,0.8473984012280706
| 3,367
|
Nucleotide transmembrane transporter activity
| 6
| 11
| 2.492749
| 0.012676
|
P41440,Q8TB61,Q9BSK2,Q99808,Q9H2D1,Q9HC21
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
102,270,274,158,123,360
|
1639,1001,1310,419,102,2019,270,158,274,123,360
|
-0.032043988936474706,0.30182221516229196,0.13707430384263497,0.7342826270023676,2.0105143282367153,-0.2058028271615026,1.031696165695717,1.522027904662708,1.031696165695717,1.7869199137107399,0.8473984012280706
| 3,367
|
Nucleotide transport
| 6
| 11
| 2.492749
| 0.012676
|
P41440,Q8TB61,Q9BSK2,Q99808,Q9H2D1,Q9HC21
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
102,270,274,158,123,360
|
1639,1001,1310,419,102,2019,270,158,274,123,360
|
-0.032043988936474706,0.30182221516229196,0.13707430384263497,0.7342826270023676,2.0105143282367153,-0.2058028271615026,1.031696165695717,1.522027904662708,1.031696165695717,1.7869199137107399,0.8473984012280706
| 3,367
|
Outer membrane
| 30
| 83
| 2.488831
| 0.012816
|
Q96TC7,Q6NUM9,Q8WXH0,Q86UT6,Q8WY22,Q13505,Q9NXE4,Q9NS69,Q9BVC6,Q99720,Q99536,O43169,Q9Y6C9,P09601,P33121,Q9NQZ5,Q9UBM7,O96008,P21796,Q96RL7,Q9BUR5,Q9NZJ7,O75431,P42345,O60313,P50402,Q9NVH0,Q9Y512,Q92667,P45880
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
406,493,404,496,138,18,561,26,432,36,164,283,167,40,530,323,63,308,309,339,203,222,443,448,209,578,510,521,500,115
|
1201,1635,2763,283,209,1296,1892,443,1719,1129,308,2241,3039,1216,40,1311,309,1061,530,2666,448,802,115,578,579,939,2400,2885,2411,18,1245,3131,650,1335,1676,1509,493,2558,1339,3133,1254,496,1085,1856,880,1165,713,2199,1345,1167,404,138,500,1604,339,406,164,2750,36,2132,203,432,1950,1529,1274,2435,2807,323,26,510,726,1111,1186,1045,1877,561,222,63,1284,1372,3145,521,167
|
0.1786609951774037,-0.032043988936474706,-0.7101048204413503,0.995247055805408,1.2109881782657737,0.13707430384263497,-0.1619123131620609,0.6961379107980552,-0.07503752950409251,0.2199786322467286,0.9217383587835264,-0.33934491131952355,-1.0035370570387363,0.1786609951774037,3.1123997852653797,0.13707430384263497,0.9217383587835264,0.26103110464403734,0.619171741197861,-0.6153160198205229,0.6961379107980552,0.42266415546022,1.8515558846925475,0.580344223839915,0.580344223839915,0.342355682402477,-0.42998258634220327,-0.8063746087452964,-0.42998258634220327,4.183049042361933,0.1786609951774037,-1.1044492003404638,0.5412829355853829,0.13707430384263497,-0.032043988936474706,0.05307774962454346,0.657768615715268,-0.5219578544209845,0.13707430384263497,-1.1044492003404638,0.1786609951774037,0.657768615715268,0.26103110464403734,-0.11832544439901459,0.38263514328382814,0.2199786322467286,0.5019846818620551,-0.29451413807445087,0.13707430384263497,0.2199786322467286,0.7722057037721174,1.6225833456176855,0.657768615715268,0.010659648604851009,0.884673610049861,0.7722057037721174,1.4541462370669627,-0.6625285072121776,3.218961116049131,-0.25000179333226685,1.246272443990728,0.7342826270023676,-0.1619123131620609,0.05307774962454346,0.1786609951774037,-0.42998258634220327,-0.7101048204413503,0.9217383587835264,3.802828202328214,0.657768615715268,0.5019846818620551,0.26103110464403734,0.2199786322467286,0.30182221516229196,-0.11832544439901459,0.619171741197861,1.2109881782657737,2.669400494336479,0.1786609951774037,0.13707430384263497,-1.1044492003404638,0.657768615715268,1.4541462370669627
| 3,367
|
Lipid homeostasis
| 8
| 23
| 2.477059
| 0.013247
|
Q5BJF2,P61916,Q8WTV0,Q9Y6C9,O15260,O15118,P34913,O15254
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
3,99,5,167,14,46,88,155
|
2054,46,155,14,1381,2913,2166,88,532,99,3175,1496,1926,3,821,1160,5,2897,1950,221,1455,2811,167
|
-0.25000179333226685,2.8943684331092254,1.522027904662708,4.34342738654226,0.09521457913715693,-0.8550813717441338,-0.29451413807445087,2.2574227850195774,0.619171741197861,2.041867375489916,-1.206907661975204,0.05307774962454346,-0.1619123131620609,6.150206234863874,0.42266415546022,0.2199786322467286,5.895453047698817,-0.8063746087452964,-0.1619123131620609,1.2109881782657737,0.09521457913715693,-0.7101048204413503,1.4541462370669627
| 3,367
|
Membrane lipid biosynthetic process
| 9
| 22
| 2.469524
| 0.013529
|
O95470,Q8NBX0,O15269,Q96G23,Q06136,Q9H490,Q99805,Q13510,P04062
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
160,230,282,38,11,235,184,90,210
|
282,1204,1812,160,210,924,1899,1410,11,1496,90,1335,230,1601,718,38,380,184,235,561,851,1708
|
0.995247055805408,0.1786609951774037,-0.11832544439901459,1.4881728202808266,1.2109881782657737,0.342355682402477,-0.1619123131620609,0.09521457913715693,4.783524978682848,0.05307774962454346,2.227038925427992,0.13707430384263497,1.1755156156311373,0.010659648604851009,0.5019846818620551,3.192469446149936,0.8099100211162025,1.3510176219205223,1.1398524773123389,0.619171741197861,0.42266415546022,-0.032043988936474706
| 3,367
|
Sphingolipid metabolism
| 6
| 11
| 2.46194
| 0.013819
|
O95470,P06280,P16278,Q06136,Q13510,P04062
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
160,67,68,11,90,210
|
282,1204,2814,160,210,67,633,68,11,90,561
|
0.995247055805408,0.1786609951774037,-0.7580513366787757,1.4881728202808266,1.2109881782657737,2.554155818031785,0.5412829355853829,2.554155818031785,4.783524978682848,2.227038925427992,0.619171741197861
| 3,367
|
Nucleobase containing compound transmembrane transporter activity
| 7
| 13
| 2.452709
| 0.014178
|
Q8TB61,P41440,L0R6Q1,Q9BSK2,Q99808,Q9H2D1,Q9HC21
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
270,102,251,274,158,123,360
|
251,1639,1001,1310,419,102,1140,2019,270,158,274,123,360
|
1.0679451413858796,-0.032043988936474706,0.30182221516229196,0.13707430384263497,0.7342826270023676,2.0105143282367153,0.2199786322467286,-0.2058028271615026,1.031696165695717,1.522027904662708,1.031696165695717,1.7869199137107399,0.8473984012280706
| 3,367
|
Abnormality of the vasculature of the eye
| 17
| 75
| 2.451369
| 0.014231
|
P07602,O00462,P06280,P16278,Q9Y4P3,P10619,Q14739,P01889,Q9NZ08,P17900,Q9NZJ7,P07686,P06865,P02786,P04066,Q13510,Q96DF8
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
34,66,67,68,302,106,76,294,148,107,222,119,84,239,94,90,290
|
681,66,1207,1638,1979,1640,479,1716,1300,792,2650,1721,294,239,94,527,2317,67,84,34,119,2318,106,2768,2769,68,107,797,483,1479,2164,1391,2664,1650,3233,576,1315,531,2254,3289,2590,1994,2255,1740,936,2880,2463,1228,2081,1405,1495,2406,1838,2181,1240,90,76,3284,1847,546,828,885,319,1090,969,970,2359,1349,290,2627,1876,148,222,514,302
|
0.5019846818620551,2.5831453876103505,0.1786609951774037,-0.032043988936474706,-0.2058028271615026,-0.032043988936474706,0.657768615715268,-0.07503752950409251,0.13707430384263497,0.42266415546022,-0.6153160198205229,-0.07503752950409251,0.9585953053509725,1.103996441331084,2.1041468018137355,0.619171741197861,-0.38449929077288447,2.554155818031785,2.3177928418789855,3.297852942116772,1.8193146884450921,-0.38449929077288447,1.9473741733456051,-0.7101048204413503,-0.7101048204413503,2.554155818031785,1.9155840365977252,0.42266415546022,0.657768615715268,0.05307774962454346,-0.29451413807445087,0.09521457913715693,-0.6153160198205229,-0.032043988936474706,-1.3634818904670298,0.580344223839915,0.13707430384263497,0.619171741197861,-0.33934491131952355,-1.632089162713181,-0.5684611504154431,-0.2058028271615026,-0.33934491131952355,-0.07503752950409251,0.342355682402477,-0.8063746087452964,-0.4758002447614249,0.1786609951774037,-0.25000179333226685,0.09521457913715693,0.05307774962454346,-0.42998258634220327,-0.11832544439901459,-0.29451413807445087,0.1786609951774037,2.227038925427992,2.4369781355796594,-1.5776059098511652,-0.11832544439901459,0.619171741197861,0.42266415546022,0.38263514328382814,0.9217383587835264,0.26103110464403734,0.342355682402477,0.342355682402477,-0.38449929077288447,0.13707430384263497,0.995247055805408,-0.5684611504154431,-0.11832544439901459,1.5892312826899408,1.2109881782657737,0.657768615715268,0.9585953053509725
| 3,367
|
Regulation of blood pressure
| 6
| 17
| 2.445499
| 0.014465
|
P42785,Q9UIQ6,P09601,P80404,P42892,Q9HB40
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
2,103,40,75,12,16
|
3001,3003,1215,40,3042,864,2,12,2077,1829,75,1664,2937,16,148,103,2646
|
-0.9536627270282968,-0.9536627270282968,0.1786609951774037,3.1123997852653797,-1.0035370570387363,0.38263514328382814,6.292167445838333,4.697545811150349,-0.25000179333226685,-0.11832544439901459,2.4369781355796594,-0.032043988936474706,-0.8550813717441338,4.320727255133443,1.5892312826899408,2.0105143282367153,-0.5684611504154431
| 3,367
|
Organic anion transport
| 12
| 39
| 2.413127
| 0.015816
|
Q9H2D1,P07602,P28288,P41440,P80404,Q9UBX3,P30825,Q9NZJ7,O60831,Q8TB61,Q9HC21,Q99808
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
123,34,197,102,75,142,201,222,362,270,360,158
|
1889,1639,362,630,2450,1304,2316,1001,2064,34,2384,1556,1310,419,1647,197,201,102,1141,807,2781,75,1495,1496,2188,2346,1584,2019,1250,270,158,123,2218,1872,360,222,142,2300,1285
|
-0.1619123131620609,-0.032043988936474706,0.8099100211162025,0.5412829355853829,-0.4758002447614249,0.13707430384263497,-0.38449929077288447,0.30182221516229196,-0.25000179333226685,3.297852942116772,-0.42998258634220327,0.010659648604851009,0.13707430384263497,0.7342826270023676,-0.032043988936474706,1.2813706494606423,1.246272443990728,2.0105143282367153,0.2199786322467286,0.42266415546022,-0.7101048204413503,2.4369781355796594,0.05307774962454346,0.05307774962454346,-0.29451413807445087,-0.38449929077288447,0.010659648604851009,-0.2058028271615026,0.1786609951774037,1.031696165695717,1.522027904662708,1.7869199137107399,-0.29451413807445087,-0.11832544439901459,0.8473984012280706,1.2109881782657737,1.6225833456176855,-0.33934491131952355,0.1786609951774037
| 3,367
|
Molecular transducer activity
| 7
| 30
| 2.402001
| 0.016306
|
Q14108,Q99720,Q8WTV0,P20645,O15118,Q5KU26,Q15629
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
32,36,5,44,46,120,60
|
786,524,46,1808,1209,2064,156,44,1061,867,2169,1740,3193,1324,2183,32,60,1584,2102,120,2796,5,972,841,36,407,511,1282,1454,2376
|
0.42266415546022,0.619171741197861,2.8943684331092254,-0.11832544439901459,0.1786609951774037,-0.25000179333226685,1.522027904662708,2.976917059317765,0.26103110464403734,0.38263514328382814,-0.29451413807445087,-0.07503752950409251,-1.2587149217723634,0.13707430384263497,-0.29451413807445087,3.5799366048175845,2.6979179668449453,0.010659648604851009,-0.25000179333226685,1.8193146884450921,-0.7101048204413503,5.895453047698817,0.342355682402477,0.42266415546022,3.218961116049131,0.7722057037721174,0.657768615715268,0.1786609951774037,0.09521457913715693,-0.38449929077288447
| 3,367
|
Basal part of cell
| 16
| 47
| 2.39377
| 0.016676
|
P42785,P19022,Q9NWH9,P41440,Q14254,O00159,P35222,P30825,Q15043,Q12846,P02786,O75955,Q6P4Q7,O94832,Q99808,Q03001
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
2,346,511,102,369,522,531,201,315,144,239,238,460,365,158,191
|
522,1052,1292,3271,238,365,239,2316,1215,2159,2384,2711,1556,1308,2068,2323,2247,346,864,1393,201,531,635,102,2,807,740,2781,1488,191,538,1324,144,1071,873,747,1578,369,315,1584,460,1590,2119,1354,1949,158,511
|
0.619171741197861,0.26103110464403734,0.13707430384263497,-1.523502876429464,1.103996441331084,0.8099100211162025,1.103996441331084,-0.38449929077288447,0.1786609951774037,-0.29451413807445087,-0.42998258634220327,-0.6625285072121776,0.010659648604851009,0.13707430384263497,-0.25000179333226685,-0.38449929077288447,-0.33934491131952355,0.8473984012280706,0.38263514328382814,0.09521457913715693,1.246272443990728,0.619171741197861,0.5412829355853829,2.0105143282367153,6.292167445838333,0.42266415546022,0.46244619964697814,-0.7101048204413503,0.05307774962454346,1.3162849902600815,0.619171741197861,0.13707430384263497,1.5892312826899408,0.26103110464403734,0.38263514328382814,0.46244619964697814,0.010659648604851009,0.8099100211162025,0.9217383587835264,0.010659648604851009,0.6961379107980552,0.010659648604851009,-0.25000179333226685,0.13707430384263497,-0.1619123131620609,1.522027904662708,0.657768615715268
| 3,367
|
Abnormality of corneal stroma
| 7
| 17
| 2.390775
| 0.016813
|
P16278,P10619,Q16625,O43933,P34913,Q13510,O43505
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
68,106,168,15,88,90,122
|
122,15,210,106,68,797,483,88,1006,1568,2181,90,168,1935,970,615,2858
|
1.7869199137107399,4.320727255133443,1.2109881782657737,1.9473741733456051,2.554155818031785,0.42266415546022,0.657768615715268,2.2574227850195774,0.30182221516229196,0.010659648604851009,-0.29451413807445087,2.227038925427992,1.419946185566603,-0.1619123131620609,0.342355682402477,0.580344223839915,-0.7580513366787757
| 3,367
|
Negative regulation of dna replication
| 7
| 11
| 2.38971
| 0.016862
|
P31949,Q7Z5K2,Q9NZC9,Q9BZE4,P54132,Q9UNS1,Q99741
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
101,427,615,556,536,117,666
|
1555,101,1487,536,708,427,1591,666,556,615,117
|
0.010659648604851009,2.0105143282367153,0.05307774962454346,0.619171741197861,0.5019846818620551,0.7342826270023676,0.010659648604851009,0.5412829355853829,0.619171741197861,0.580344223839915,1.8515558846925475
| 3,367
|
Abnormality of the autonomic nervous system
| 17
| 65
| 2.38557
| 0.017053
|
Q10713,P07602,P06280,Q9UJX6,O15269,P41440,P42892,Q96RL7,Q9NZJ7,Q99996,Q96EK5,P07686,P04062,O15360,O76024,Q9UBM7,Q8N3U4
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
287,34,67,134,282,102,12,339,222,116,321,119,210,121,364,63,289
|
1202,282,1204,121,2814,997,479,688,364,2156,210,67,34,119,633,1218,1391,393,3289,637,3048,102,12,934,3049,1829,2081,3015,1919,1837,287,2839,1153,1926,1415,545,1338,1159,2484,3133,289,2199,969,970,2359,321,2621,837,1608,339,721,3304,116,768,1443,2627,1870,1874,1621,222,63,134,1373,2994,1804
|
0.1786609951774037,0.995247055805408,0.1786609951774037,1.7869199137107399,-0.7580513366787757,0.30182221516229196,0.657768615715268,0.5019846818620551,0.8099100211162025,-0.29451413807445087,1.2109881782657737,2.554155818031785,3.297852942116772,1.8193146884450921,0.5412829355853829,0.1786609951774037,0.09521457913715693,0.7722057037721174,-1.632089162713181,0.5412829355853829,-1.0035370570387363,2.0105143282367153,4.697545811150349,0.342355682402477,-1.0035370570387363,-0.11832544439901459,-0.25000179333226685,-0.9536627270282968,-0.1619123131620609,-0.11832544439901459,0.995247055805408,-0.7580513366787757,0.2199786322467286,-0.1619123131620609,0.09521457913715693,0.619171741197861,0.13707430384263497,0.2199786322467286,-0.4758002447614249,-1.1044492003404638,0.995247055805408,-0.29451413807445087,0.342355682402477,0.342355682402477,-0.38449929077288447,0.9217383587835264,-0.5684611504154431,0.42266415546022,0.010659648604851009,0.884673610049861,0.5019846818620551,-1.7421936575233459,1.8515558846925475,0.46244619964697814,0.09521457913715693,-0.5684611504154431,-0.11832544439901459,-0.11832544439901459,0.010659648604851009,1.2109881782657737,2.669400494336479,1.6557714498436458,0.13707430384263497,-0.9041772408267448,-0.07503752950409251
| 3,367
|
Glycosylation
| 16
| 45
| 2.369802
| 0.017798
|
O60502,Q86SF2,Q9UP83,Q10471,Q2TAA5,Q6ZXV5,Q16706,O60476,O15118,Q9H0U3,P46977,O75503,O75352,Q08379,O43505,P04062
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
64,256,473,312,350,297,335,81,46,322,422,24,363,212,122,210
|
1548,46,2308,122,81,64,1642,1812,3325,363,24,2706,210,1983,919,2721,422,2544,2180,872,2408,212,312,452,1327,1329,335,350,297,1853,256,1776,661,1606,2125,1787,322,674,2808,1187,2144,473,2950,905,1121
|
0.010659648604851009,2.8943684331092254,-0.38449929077288447,1.7869199137107399,2.377641277448686,2.640766626646635,-0.032043988936474706,-0.11832544439901459,-1.9101855426565795,0.8099100211162025,3.8514472696790003,-0.6625285072121776,1.2109881782657737,-0.2058028271615026,0.342355682402477,-0.6625285072121776,0.7342826270023676,-0.5219578544209845,-0.29451413807445087,0.38263514328382814,-0.42998258634220327,1.2109881782657737,0.9217383587835264,0.6961379107980552,0.13707430384263497,0.13707430384263497,0.884673610049861,0.8473984012280706,0.9585953053509725,-0.11832544439901459,1.0679451413858796,-0.07503752950409251,0.5412829355853829,0.010659648604851009,-0.25000179333226685,-0.07503752950409251,0.9217383587835264,0.5412829355853829,-0.7101048204413503,0.2199786322467286,-0.25000179333226685,0.6961379107980552,-0.8550813717441338,0.38263514328382814,0.26103110464403734
| 3,367
|
Ion transmembrane transporter activity
| 26
| 80
| 2.365232
| 0.018019
|
Q70HW3,Q9UBX3,Q8TB61,Q99808,Q9BVC6,O43772,P12236,Q15043,Q9H0U3,Q9Y487,Q9HD20,Q9C0H2,Q6P4Q7,Q93050,P21796,P47985,P30825,O75964,P16615,Q9HC21,P41440,P13073,Q13423,Q9UI12,P45880,Q9H2D1
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
13,142,270,158,432,42,419,315,322,186,185,56,460,62,309,449,201,89,211,360,102,232,233,249,115,123
|
2305,1889,2814,42,1639,630,2865,89,690,1304,693,1215,1001,1896,2159,2710,2384,529,3338,1385,1556,1310,419,232,211,864,2249,1732,2871,309,1562,1989,201,1394,2719,2875,2591,102,115,449,3332,641,1141,807,2781,645,2401,1011,871,1069,1495,233,3276,315,1584,594,2019,1250,460,13,1683,270,972,62,158,432,56,322,123,2218,1872,360,185,142,512,249,1285,1372,186,1376
|
-0.38449929077288447,-0.1619123131620609,-0.7580513366787757,3.0585160335120065,-0.032043988936474706,0.5412829355853829,-0.8063746087452964,2.227038925427992,0.5019846818620551,0.13707430384263497,0.5019846818620551,0.1786609951774037,0.30182221516229196,-0.1619123131620609,-0.29451413807445087,-0.6625285072121776,-0.42998258634220327,0.619171741197861,-2.197689911987167,0.09521457913715693,0.010659648604851009,0.13707430384263497,0.7342826270023676,1.1398524773123389,1.2109881782657737,0.38263514328382814,-0.33934491131952355,-0.07503752950409251,-0.8063746087452964,0.9217383587835264,0.010659648604851009,-0.2058028271615026,1.246272443990728,0.09521457913715693,-0.6625285072121776,-0.8063746087452964,-0.5684611504154431,2.0105143282367153,1.8515558846925475,0.6961379107980552,-2.024062737158297,0.5412829355853829,0.2199786322467286,0.42266415546022,-0.7101048204413503,0.5412829355853829,-0.42998258634220327,0.30182221516229196,0.38263514328382814,0.26103110464403734,0.05307774962454346,1.1398524773123389,-1.523502876429464,0.9217383587835264,0.010659648604851009,0.580344223839915,-0.2058028271615026,0.1786609951774037,0.6961379107980552,4.433541950109594,-0.032043988936474706,1.031696165695717,0.342355682402477,2.669400494336479,1.522027904662708,0.7342826270023676,2.782782542710472,0.9217383587835264,1.7869199137107399,-0.29451413807445087,-0.11832544439901459,0.8473984012280706,1.3510176219205223,1.6225833456176855,0.657768615715268,1.103996441331084,0.1786609951774037,0.13707430384263497,1.3510176219205223,0.13707430384263497
| 3,367
|
Endopeptidase activity
| 15
| 64
| 2.345582
| 0.018997
|
Q8TCT9,Q10713,P67812,Q70CQ2,P42892,Q9NZ08,Q99538,O75844,O14773,Q4J6C6,P49721,Q92542,P07384,P60900,Q2T9J0
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
354,287,285,298,12,148,177,113,20,268,22,218,240,242,157
|
20,1469,1813,113,2158,240,2659,2068,1730,798,1820,2663,1650,485,2455,2326,1652,1062,1137,2780,12,2877,3261,2879,22,2882,580,869,3282,242,285,287,453,1241,2613,371,157,268,542,2479,2106,298,1025,1169,354,218,1601,2120,971,1032,1352,2849,1437,2209,177,2804,1699,148,2372,1188,1117,731,2052,1289
|
3.9953969719732,0.05307774962454346,-0.11832544439901459,1.8515558846925475,-0.29451413807445087,1.103996441331084,-0.6153160198205229,-0.25000179333226685,-0.07503752950409251,0.42266415546022,-0.11832544439901459,-0.6153160198205229,-0.032043988936474706,0.657768615715268,-0.4758002447614249,-0.38449929077288447,-0.032043988936474706,0.26103110464403734,0.2199786322467286,-0.7101048204413503,4.697545811150349,-0.8063746087452964,-1.4697807385854578,-0.8063746087452964,3.8997452806748156,-0.8063746087452964,0.580344223839915,0.38263514328382814,-1.5776059098511652,1.103996441331084,0.995247055805408,0.995247055805408,0.6961379107980552,0.1786609951774037,-0.5684611504154431,0.8099100211162025,1.522027904662708,1.031696165695717,0.619171741197861,-0.4758002447614249,-0.25000179333226685,0.9585953053509725,0.30182221516229196,0.2199786322467286,0.8473984012280706,1.2109881782657737,0.010659648604851009,-0.25000179333226685,0.342355682402477,0.30182221516229196,0.13707430384263497,-0.7580513366787757,0.09521457913715693,-0.29451413807445087,1.3855706609057188,-0.7101048204413503,-0.032043988936474706,1.5892312826899408,-0.38449929077288447,0.2199786322467286,0.26103110464403734,0.5019846818620551,-0.2058028271615026,0.1786609951774037
| 3,367
|
SLC25 family of mitochondrial transporters
| 8
| 19
| 2.34097
| 0.019234
|
Q9Y6C9,O43772,Q70HW3,Q9UBX3,Q9BSK2,Q9NZJ7,Q9H2D1,Q9HC21
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
167,42,13,142,274,222,123,360
|
42,1639,630,1001,1310,419,1141,1069,1495,2019,13,274,123,2218,360,222,142,1285,167
|
3.0585160335120065,-0.032043988936474706,0.5412829355853829,0.30182221516229196,0.13707430384263497,0.7342826270023676,0.2199786322467286,0.26103110464403734,0.05307774962454346,-0.2058028271615026,4.433541950109594,1.031696165695717,1.7869199137107399,-0.29451413807445087,0.8473984012280706,1.2109881782657737,1.6225833456176855,0.1786609951774037,1.4541462370669627
| 3,367
|
Mitochondrial carrier domain superfamily [IPR023395]
| 8
| 19
| 2.34097
| 0.019234
|
Q9Y6C9,O43772,Q70HW3,Q9UBX3,Q9BSK2,Q9NZJ7,Q9H2D1,Q9HC21
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
167,42,13,142,274,222,123,360
|
42,1639,630,1001,1310,419,1141,1069,1495,2019,13,274,123,2218,360,222,142,1285,167
|
3.0585160335120065,-0.032043988936474706,0.5412829355853829,0.30182221516229196,0.13707430384263497,0.7342826270023676,0.2199786322467286,0.26103110464403734,0.05307774962454346,-0.2058028271615026,4.433541950109594,1.031696165695717,1.7869199137107399,-0.29451413807445087,0.8473984012280706,1.2109881782657737,1.6225833456176855,0.1786609951774037,1.4541462370669627
| 3,367
|
Mitochondrial substrate/solute carrier [IPR018108]
| 8
| 19
| 2.34097
| 0.019234
|
Q9Y6C9,O43772,Q70HW3,Q9UBX3,Q9BSK2,Q9NZJ7,Q9H2D1,Q9HC21
|
Sequence
|
InterPro Repeat
|
interpro_repeat
|
167,42,13,142,274,222,123,360
|
42,1639,630,1001,1310,419,1141,1069,1495,2019,13,274,123,2218,360,222,142,1285,167
|
3.0585160335120065,-0.032043988936474706,0.5412829355853829,0.30182221516229196,0.13707430384263497,0.7342826270023676,0.2199786322467286,0.26103110464403734,0.05307774962454346,-0.2058028271615026,4.433541950109594,1.031696165695717,1.7869199137107399,-0.29451413807445087,0.8473984012280706,1.2109881782657737,1.6225833456176855,0.1786609951774037,1.4541462370669627
| 3,367
|
Glycerolipid biosynthetic process
| 12
| 47
| 2.333501
| 0.019622
|
Q92604,Q8NCC3,Q10713,P42356,Q96Q15,Q8WTV0,Q96N66,Q9H490,P35790,O95674,Q86TV6,Q9UG56
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
259,0,287,198,98,5,133,235,48,330,182,361
|
570,1975,624,2702,1812,1129,330,3230,2956,1730,3189,530,48,198,738,1571,287,1073,1663,1156,426,182,1774,0,883,2202,5,3069,758,259,1601,718,2122,133,98,380,3321,975,2032,1099,1951,1359,235,2696,1706,361,566
|
0.580344223839915,-0.2058028271615026,0.5412829355853829,-0.6625285072121776,-0.11832544439901459,0.2199786322467286,0.884673610049861,-1.3634818904670298,-0.9041772408267448,-0.07503752950409251,-1.2587149217723634,0.619171741197861,2.8943684331092254,1.2813706494606423,0.46244619964697814,0.010659648604851009,0.995247055805408,0.26103110464403734,-0.032043988936474706,0.2199786322467286,0.7342826270023676,1.3510176219205223,-0.07503752950409251,6.753408671655479,0.38263514328382814,-0.29451413807445087,5.895453047698817,-1.0035370570387363,0.46244619964697814,1.0679451413858796,0.010659648604851009,0.5019846818620551,-0.25000179333226685,1.6557714498436458,2.0730777150539357,0.8099100211162025,-1.853811091154964,0.342355682402477,-0.2058028271615026,0.26103110464403734,-0.1619123131620609,0.13707430384263497,1.1398524773123389,-0.6153160198205229,-0.032043988936474706,0.8473984012280706,0.619171741197861
| 3,367
|
Myoclonic seizure
| 9
| 56
| 2.317876
| 0.020456
|
P07602,P16278,Q9UJX6,Q96N66,Q9NZJ7,P07686,O75503,Q13510,P04062
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
34,68,134,133,222,119,24,90,210
|
1635,1465,2953,2512,628,2863,1812,24,1720,210,34,119,1556,68,2164,576,867,1484,1485,3309,1829,2080,3124,1404,1232,1494,2785,2610,2788,90,1761,2792,1153,954,1509,1338,1681,1516,718,2747,761,973,837,133,2035,1443,2693,2218,724,222,1961,134,326,2441,1195,1289
|
-0.032043988936474706,0.05307774962454346,-0.9041772408267448,-0.5219578544209845,0.5412829355853829,-0.8063746087452964,-0.11832544439901459,3.8514472696790003,-0.07503752950409251,1.2109881782657737,3.297852942116772,1.8193146884450921,0.010659648604851009,2.554155818031785,-0.29451413807445087,0.580344223839915,0.38263514328382814,0.05307774962454346,0.05307774962454346,-1.7978135821100152,-0.11832544439901459,-0.25000179333226685,-1.1044492003404638,0.09521457913715693,0.1786609951774037,0.05307774962454346,-0.7101048204413503,-0.5684611504154431,-0.7101048204413503,2.227038925427992,-0.07503752950409251,-0.7101048204413503,0.2199786322467286,0.342355682402477,0.05307774962454346,0.13707430384263497,-0.032043988936474706,0.05307774962454346,0.5019846818620551,-0.6625285072121776,0.46244619964697814,0.342355682402477,0.42266415546022,1.6557714498436458,-0.2058028271615026,0.09521457913715693,-0.6153160198205229,-0.29451413807445087,0.5019846818620551,1.2109881782657737,-0.1619123131620609,1.6557714498436458,0.9217383587835264,-0.42998258634220327,0.2199786322467286,0.1786609951774037
| 3,367
|
Receptor
| 9
| 28
| 2.29602
| 0.021675
|
Q14108,Q8WTV0,Q567V2,Q9NR77,P20645,Q9UQB8,Q9HCD5,A6NIH7,P11717
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
32,5,72,278,44,45,383,57,156
|
57,1637,1295,1891,2448,631,918,2064,156,44,2169,454,32,747,1583,72,2106,2796,1160,5,2027,407,1110,383,278,1047,1192,45
|
2.754607952931739,-0.032043988936474706,0.13707430384263497,-0.1619123131620609,-0.4758002447614249,0.5412829355853829,0.342355682402477,-0.25000179333226685,1.522027904662708,2.976917059317765,-0.29451413807445087,0.6961379107980552,3.5799366048175845,0.46244619964697814,0.010659648604851009,2.4958131623722344,-0.25000179333226685,-0.7101048204413503,0.2199786322467286,5.895453047698817,-0.2058028271615026,0.7722057037721174,0.26103110464403734,0.8099100211162025,1.031696165695717,0.30182221516229196,0.2199786322467286,2.9495075939089457
| 3,367
|
Nuclear membrane
| 25
| 64
| 2.287973
| 0.022139
|
Q8WXH0,Q9UH99,Q9BZE4,Q9H1E5,Q8WUM0,O15260,Q9NXE4,P12270,Q149N8,Q9BVC6,P57740,P67812,Q9BTX1,Q96G23,O75694,Q9Y5Q9,O75976,O00560,Q8IY37,Q8WYP5,Q9NXW2,Q14739,A2RRP1,P50402,O75179
|
Localization
|
Protein Atlas Subcellular
|
protein_atlas_subcellular_location_all
|
404,280,556,276,552,14,561,392,649,432,646,285,165,38,526,439,175,188,599,465,204,76,569,578,480
|
569,188,1975,1637,14,1467,480,526,175,1894,1722,3205,2767,392,2528,1218,2395,1903,739,804,578,645,646,285,812,76,1665,649,2932,2552,1506,1158,2112,1855,1593,599,1171,2894,552,404,465,38,2030,764,2804,1439,2898,165,432,2429,556,276,1791,1874,561,204,280,2856,2641,2576,3080,1969,1374,439
|
0.580344223839915,1.3162849902600815,-0.2058028271615026,-0.032043988936474706,4.34342738654226,0.05307774962454346,0.657768615715268,0.619171741197861,1.3855706609057188,-0.1619123131620609,-0.07503752950409251,-1.3109065691871442,-0.7101048204413503,0.7722057037721174,-0.5219578544209845,0.1786609951774037,-0.42998258634220327,-0.1619123131620609,0.46244619964697814,0.42266415546022,0.580344223839915,0.5412829355853829,0.5412829355853829,0.995247055805408,0.42266415546022,2.4369781355796594,-0.032043988936474706,0.5412829355853829,-0.8550813717441338,-0.5219578544209845,0.05307774962454346,0.2199786322467286,-0.25000179333226685,-0.11832544439901459,0.010659648604851009,0.580344223839915,0.2199786322467286,-0.8063746087452964,0.619171741197861,0.7722057037721174,0.6961379107980552,3.192469446149936,-0.2058028271615026,0.46244619964697814,-0.7101048204413503,0.09521457913715693,-0.8063746087452964,1.4541462370669627,0.7342826270023676,-0.42998258634220327,0.619171741197861,1.031696165695717,-0.07503752950409251,-0.11832544439901459,0.619171741197861,1.246272443990728,1.031696165695717,-0.7580513366787757,-0.5684611504154431,-0.5219578544209845,-1.0035370570387363,-0.1619123131620609,0.13707430384263497,0.7342826270023676
| 3,367
|
Translocation
| 25
| 47
| 2.276336
| 0.022826
|
P49790,P61619,P35658,O14925,Q8WUM0,Q9NS69,P12270,P57740,Q9UBU9,Q9BTX1,O75694,O00159,Q99442,Q99595,Q15629,Q8WYP5,P49792,Q92621,Q9Y5L4,P52948,Q99567,O60830,Q12769,Q8N1F7,P60059
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
739,871,636,623,552,26,392,646,852,165,526,522,841,178,60,465,804,338,223,806,765,96,584,882,241
|
522,623,996,96,2448,526,392,636,2395,739,804,806,870,646,241,1747,871,2885,3158,584,60,1077,1770,1771,1589,882,2284,1170,1171,1858,1425,552,465,338,1523,841,765,178,165,2626,1357,1874,26,1282,852,2576,223
|
0.619171741197861,0.5412829355853829,0.30182221516229196,2.0730777150539357,-0.4758002447614249,0.619171741197861,0.7722057037721174,0.5412829355853829,-0.42998258634220327,0.46244619964697814,0.42266415546022,0.42266415546022,0.38263514328382814,0.5412829355853829,1.103996441331084,-0.07503752950409251,0.38263514328382814,-0.8063746087452964,-1.1554855115344582,0.580344223839915,2.6979179668449453,0.26103110464403734,-0.07503752950409251,-0.07503752950409251,0.010659648604851009,0.38263514328382814,-0.33934491131952355,0.2199786322467286,0.2199786322467286,-0.11832544439901459,0.09521457913715693,0.619171741197861,0.6961379107980552,0.884673610049861,0.05307774962454346,0.42266415546022,0.46244619964697814,1.3855706609057188,1.4541462370669627,-0.5684611504154431,0.13707430384263497,-0.11832544439901459,3.802828202328214,0.1786609951774037,0.42266415546022,-0.5219578544209845,1.2109881782657737
| 3,367
|
Retinal degeneration
| 19
| 56
| 2.272692
| 0.023045
|
O14773,O75648,P42858,O75503,P50897,Q6P2Q9,Q10713,P04439,Q8IY17,Q96F07,P51648,Q14191,Q13510,O00754,P04062,O60313,Q9UG56,Q7LGA3,P19447
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
20,389,265,24,29,546,287,527,316,199,333,215,90,208,210,209,361,374,483
|
2761,208,20,1207,209,2383,24,792,389,1726,1816,210,527,1476,797,1311,483,1479,1821,2664,531,2591,265,2723,2880,29,333,3014,2781,3157,1146,1232,2785,2610,287,1411,90,215,1152,546,374,655,316,2976,1424,885,1090,199,2127,2210,2624,2627,361,3270,2507,3299
|
-0.7101048204413503,1.2109881782657737,3.9953969719732,0.1786609951774037,1.2109881782657737,-0.42998258634220327,3.8514472696790003,0.42266415546022,0.7722057037721174,-0.07503752950409251,-0.11832544439901459,1.2109881782657737,0.619171741197861,0.05307774962454346,0.42266415546022,0.13707430384263497,0.657768615715268,0.05307774962454346,-0.11832544439901459,-0.6153160198205229,0.619171741197861,-0.5684611504154431,1.031696165695717,-0.6625285072121776,-0.8063746087452964,3.679843814797915,0.884673610049861,-0.9536627270282968,-0.7101048204413503,-1.1554855115344582,0.2199786322467286,0.1786609951774037,-0.7101048204413503,-0.5684611504154431,0.995247055805408,0.09521457913715693,2.227038925427992,1.2109881782657737,0.2199786322467286,0.619171741197861,0.8099100211162025,0.5412829355853829,0.9217383587835264,-0.9041772408267448,0.09521457913715693,0.38263514328382814,0.26103110464403734,1.2813706494606423,-0.25000179333226685,-0.29451413807445087,-0.5684611504154431,-0.5684611504154431,0.8473984012280706,-1.4697807385854578,-0.4758002447614249,-1.686951965968084
| 3,367
|
Mental deterioration
| 28
| 100
| 2.246323
| 0.024683
|
P42858,O75503,Q9BQE5,P50897,Q14108,O95470,P07602,Q10713,O15118,Q9Y487,Q8IY17,Q9NQZ5,P54802,O96008,P16278,Q96F07,Q96RL7,Q9NZJ7,P05067,Q9NPL8,P06865,Q13510,P04062,O60313,P04350,P61916,P17900,P07686
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
265,24,27,29,32,160,34,287,46,186,316,323,65,308,68,199,339,222,83,87,84,90,210,209,366,99,107,119
|
1635,46,2814,858,209,2060,688,1300,24,364,160,308,693,210,3337,366,83,84,34,119,3207,2524,1305,1476,1058,633,68,923,107,797,1218,2164,1391,2072,865,1899,576,2168,421,2875,2591,802,265,1484,933,2723,29,2832,1829,65,1568,1745,99,3157,1232,1572,3015,1919,2785,1837,2610,287,2411,1923,945,90,32,1330,2551,877,1509,1772,824,2484,3133,316,2199,758,970,1519,199,1608,339,721,3304,2210,27,2131,87,323,900,2991,222,2143,774,3270,1373,2994,186,3299
|
-0.032043988936474706,2.8943684331092254,-0.7580513366787757,0.38263514328382814,1.2109881782657737,-0.25000179333226685,0.5019846818620551,0.13707430384263497,3.8514472696790003,0.8099100211162025,1.4881728202808266,0.9217383587835264,0.5019846818620551,1.2109881782657737,-2.197689911987167,0.8099100211162025,2.3477816274627044,2.3177928418789855,3.297852942116772,1.8193146884450921,-1.3109065691871442,-0.5219578544209845,0.13707430384263497,0.05307774962454346,0.26103110464403734,0.5412829355853829,2.554155818031785,0.342355682402477,1.9155840365977252,0.42266415546022,0.1786609951774037,-0.29451413807445087,0.09521457913715693,-0.25000179333226685,0.38263514328382814,-0.1619123131620609,0.580344223839915,-0.29451413807445087,0.7342826270023676,-0.8063746087452964,-0.5684611504154431,0.42266415546022,1.031696165695717,0.05307774962454346,0.342355682402477,-0.6625285072121776,3.679843814797915,-0.7580513366787757,-0.11832544439901459,2.640766626646635,0.010659648604851009,-0.07503752950409251,2.041867375489916,-1.1554855115344582,0.1786609951774037,0.010659648604851009,-0.9536627270282968,-0.1619123131620609,-0.7101048204413503,-0.11832544439901459,-0.5684611504154431,0.995247055805408,-0.42998258634220327,-0.1619123131620609,0.342355682402477,2.227038925427992,3.5799366048175845,0.13707430384263497,-0.5219578544209845,0.38263514328382814,0.05307774962454346,-0.07503752950409251,0.42266415546022,-0.4758002447614249,-1.1044492003404638,0.9217383587835264,-0.29451413807445087,0.46244619964697814,0.342355682402477,0.05307774962454346,1.2813706494606423,0.010659648604851009,0.884673610049861,0.5019846818620551,-1.7421936575233459,-0.29451413807445087,3.7292869846617753,-0.25000179333226685,2.3177928418789855,0.9217383587835264,0.38263514328382814,-0.9041772408267448,1.2109881782657737,-0.25000179333226685,0.46244619964697814,-1.4697807385854578,0.13707430384263497,-0.9041772408267448,1.3510176219205223,-1.686951965968084
| 3,367
|
Protein processing
| 14
| 42
| 2.245812
| 0.024716
|
Q10713,P67812,Q96F07,Q9NQH7,P42892,O75976,Q99538,O75844,Q92896,Q92542,O75503,Q2T9J0,Q15392,Q9UG56
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
287,285,199,61,12,175,177,113,52,218,24,157,28,361
|
2308,2309,1813,24,113,175,2708,3170,3039,2159,1383,1730,3280,737,1137,2780,12,2597,2542,285,287,1070,2736,28,157,542,2479,1081,1346,354,218,52,199,2983,1437,177,2804,61,361,1964,3240,1289
|
-0.38449929077288447,-0.38449929077288447,-0.11832544439901459,3.8514472696790003,1.8515558846925475,1.3855706609057188,-0.6625285072121776,-1.206907661975204,-1.0035370570387363,-0.29451413807445087,0.09521457913715693,-0.07503752950409251,-1.5776059098511652,0.46244619964697814,0.2199786322467286,-0.7101048204413503,4.697545811150349,-0.5684611504154431,-0.5219578544209845,0.995247055805408,0.995247055805408,0.26103110464403734,-0.6625285072121776,3.7046073923024947,1.522027904662708,0.619171741197861,-0.4758002447614249,0.26103110464403734,0.13707430384263497,0.8473984012280706,1.2109881782657737,2.810844890271643,1.2813706494606423,-0.9041772408267448,0.09521457913715693,1.3855706609057188,-0.7101048204413503,2.6979179668449453,0.8473984012280706,-0.1619123131620609,-1.3634818904670298,0.1786609951774037
| 3,367
|
Glycerolipid metabolic process
| 23
| 65
| 2.244134
| 0.024824
|
Q92604,Q8NCC3,Q8N9F7,Q8WTV0,Q96N66,Q9NXE4,Q9Y217,Q10713,Q6IAN0,P33121,P35790,Q86TV6,Q8IY17,Q9BZF1,P42356,O95674,O00443,Q9UG56,P50416,Q96Q15,Q9H490,Q96S52,Q8N2K0
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
259,0,403,5,133,561,566,287,426,530,48,182,316,192,198,330,570,361,579,98,235,380,659
|
3200,570,1975,624,2702,1812,1129,330,3230,2956,1730,1390,3189,3247,530,48,932,198,1485,738,579,1829,1571,2786,287,1073,1663,1156,1335,426,182,1774,316,659,403,0,883,2202,5,3069,758,259,1601,718,2122,2897,133,98,380,3321,975,2750,2032,1099,1951,1359,192,1868,235,2696,1706,561,361,1964,566
|
-1.3109065691871442,0.580344223839915,-0.2058028271615026,0.5412829355853829,-0.6625285072121776,-0.11832544439901459,0.2199786322467286,0.884673610049861,-1.3634818904670298,-0.9041772408267448,-0.07503752950409251,0.09521457913715693,-1.2587149217723634,-1.416440179685344,0.619171741197861,2.8943684331092254,0.342355682402477,1.2813706494606423,0.05307774962454346,0.46244619964697814,0.580344223839915,-0.11832544439901459,0.010659648604851009,-0.7101048204413503,0.995247055805408,0.26103110464403734,-0.032043988936474706,0.2199786322467286,0.13707430384263497,0.7342826270023676,1.3510176219205223,-0.07503752950409251,0.9217383587835264,0.5412829355853829,0.7722057037721174,6.753408671655479,0.38263514328382814,-0.29451413807445087,5.895453047698817,-1.0035370570387363,0.46244619964697814,1.0679451413858796,0.010659648604851009,0.5019846818620551,-0.25000179333226685,-0.8063746087452964,1.6557714498436458,2.0730777150539357,0.8099100211162025,-1.853811091154964,0.342355682402477,-0.6625285072121776,-0.2058028271615026,0.26103110464403734,-0.1619123131620609,0.13707430384263497,1.3162849902600815,-0.11832544439901459,1.1398524773123389,-0.6153160198205229,-0.032043988936474706,0.619171741197861,0.8473984012280706,-0.1619123131620609,0.619171741197861
| 3,367
|
Abnormal epiphyseal ossification
| 6
| 17
| 2.232855
| 0.025559
|
Q96HA7,Q14739,O43933,Q2M1P5,Q9UG56,Q9UBM7
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
231,76,15,217,361,63
|
1200,15,1471,2448,1058,1994,394,76,1243,589,2098,217,231,1605,1606,63,361
|
0.1786609951774037,4.320727255133443,0.05307774962454346,-0.4758002447614249,0.26103110464403734,-0.2058028271615026,0.7722057037721174,2.4369781355796594,0.1786609951774037,0.580344223839915,-0.25000179333226685,1.2109881782657737,1.1755156156311373,0.010659648604851009,0.010659648604851009,2.669400494336479,0.8473984012280706
| 3,367
|
Cholesterol binding
| 7
| 14
| 2.22134
| 0.026328
|
Q9BZF1,Q14108,P61916,Q14849,Q9H4L5,O15118,P45880
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
192,32,99,49,147,46,115
|
46,2315,2710,309,3121,1061,532,115,99,32,49,192,2215,147
|
2.8943684331092254,-0.38449929077288447,-0.6625285072121776,0.9217383587835264,-1.1044492003404638,0.26103110464403734,0.619171741197861,1.8515558846925475,2.041867375489916,3.5799366048175845,2.8943684331092254,1.3162849902600815,-0.29451413807445087,1.5892312826899408
| 3,367
|
Serine hydrolase activity
| 8
| 19
| 2.213366
| 0.026872
|
Q9H3G5,P42785,P10619,O75976,Q9HB40,Q4J6C6,O14773,Q2T9J0
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
1,2,106,175,16,268,20,157
|
20,175,106,2659,2326,1062,2,3261,806,869,285,371,157,268,542,2106,3194,1,16
|
3.9953969719732,1.3855706609057188,1.9473741733456051,-0.6153160198205229,-0.38449929077288447,0.26103110464403734,6.292167445838333,-1.4697807385854578,0.42266415546022,0.38263514328382814,0.995247055805408,0.8099100211162025,1.522027904662708,1.031696165695717,0.619171741197861,-0.25000179333226685,-1.2587149217723634,6.653184264123767,4.320727255133443
| 3,367
|
Protein maturation
| 17
| 68
| 2.206957
| 0.027317
|
Q8TCT9,Q10713,P67812,Q96F07,Q10471,Q9NQH7,P42892,O75976,Q99538,O75844,Q92896,Q92542,Q9BU23,O75503,Q2T9J0,Q15392,Q9UG56
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
354,287,285,199,312,61,12,175,177,113,52,218,220,24,157,28,361
|
907,2308,2309,1813,24,113,175,3168,364,1553,2708,3170,3039,2159,1383,2161,1730,3280,2774,737,3048,1137,2780,12,1906,2597,2542,940,285,312,287,1070,1756,1579,1666,2736,28,157,542,2479,1081,3020,2280,1083,1346,354,218,52,199,2983,1527,1437,177,2804,220,670,2366,1869,2806,61,1793,676,361,1964,1115,3240,3270,1289
|
0.342355682402477,-0.38449929077288447,-0.38449929077288447,-0.11832544439901459,3.8514472696790003,1.8515558846925475,1.3855706609057188,-1.206907661975204,0.8099100211162025,0.010659648604851009,-0.6625285072121776,-1.206907661975204,-1.0035370570387363,-0.29451413807445087,0.09521457913715693,-0.29451413807445087,-0.07503752950409251,-1.5776059098511652,-0.7101048204413503,0.46244619964697814,-1.0035370570387363,0.2199786322467286,-0.7101048204413503,4.697545811150349,-0.1619123131620609,-0.5684611504154431,-0.5219578544209845,0.342355682402477,0.995247055805408,0.9217383587835264,0.995247055805408,0.26103110464403734,-0.07503752950409251,0.010659648604851009,-0.032043988936474706,-0.6625285072121776,3.7046073923024947,1.522027904662708,0.619171741197861,-0.4758002447614249,0.26103110464403734,-0.9536627270282968,-0.33934491131952355,0.26103110464403734,0.13707430384263497,0.8473984012280706,1.2109881782657737,2.810844890271643,1.2813706494606423,-0.9041772408267448,0.05307774962454346,0.09521457913715693,1.3855706609057188,-0.7101048204413503,1.2109881782657737,0.5412829355853829,-0.38449929077288447,-0.11832544439901459,-0.7101048204413503,2.6979179668449453,-0.07503752950409251,0.5412829355853829,0.8473984012280706,-0.1619123131620609,0.26103110464403734,-1.3634818904670298,-1.4697807385854578,0.1786609951774037
| 3,367
|
Cis golgi network
| 8
| 14
| 2.20236
| 0.02764
|
Q86VS8,Q14789,Q16706,O00461,P24390,Q99996,Q9NPR9,Q08379
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
161,456,335,80,47,116,154,212
|
80,3083,47,2328,1010,212,456,335,161,1685,1686,116,154,516
|
2.377641277448686,-1.053799466605388,2.8943684331092254,-0.38449929077288447,0.30182221516229196,1.2109881782657737,0.6961379107980552,0.884673610049861,1.4881728202808266,-0.032043988936474706,-0.032043988936474706,1.8515558846925475,1.5557134250916398,0.657768615715268
| 3,367
|
Nuclear pore complex assembly
| 8
| 9
| 2.190655
| 0.028477
|
P49790,P57740,Q9BTX1,Q92621,Q9NQC3,P52948,P12270,Q8WYP5
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
739,646,165,338,221,806,392,465
|
392,739,806,646,882,465,338,165,221
|
0.7722057037721174,0.46244619964697814,0.42266415546022,0.5412829355853829,0.38263514328382814,0.6961379107980552,0.884673610049861,1.4541462370669627,1.2109881782657737
| 3,367
|
membrane trafficking regulatory protein
| 8
| 21
| 2.180509
| 0.02922
|
Q15075,Q14108,Q8WTV0,P24390,Q8WU76,P11279,O00560,P13473
|
Functions
|
Panther Protein class
|
panther_protein_class
|
370,32,5,47,356,150,188,30
|
1052,385,188,2311,1723,150,30,47,32,370,2737,876,5,356,1685,1349,1269,3073,2632,1708,2575
|
0.26103110464403734,0.7722057037721174,1.3162849902600815,-0.38449929077288447,-0.07503752950409251,1.5557134250916398,3.6549956055948876,2.8943684331092254,3.5799366048175845,0.8099100211162025,-0.6625285072121776,0.38263514328382814,5.895453047698817,0.8473984012280706,-0.032043988936474706,0.13707430384263497,0.1786609951774037,-1.0035370570387363,-0.5684611504154431,-0.032043988936474706,-0.5219578544209845
| 3,367
|
Intracellular calcium-sensing protein
| 6
| 13
| 2.179015
| 0.029331
|
Q14257,P31949,P80303,Q9BRK5,O43852,Q02818
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
128,101,10,146,237,93
|
237,101,2337,10,93,128,2793,351,1940,2487,2424,668,146
|
1.103996441331084,2.0105143282367153,-0.38449929077288447,4.783524978682848,2.1658669221988482,1.7216629695769743,-0.7101048204413503,0.8473984012280706,-0.1619123131620609,-0.4758002447614249,-0.42998258634220327,0.5412829355853829,1.5892312826899408
| 3,367
|
Calmodulin
| 6
| 13
| 2.179015
| 0.029331
|
Q14257,P31949,P80303,Q9BRK5,O43852,Q02818
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
128,101,10,146,237,93
|
237,101,2337,10,93,128,2793,351,1940,2487,2424,668,146
|
1.103996441331084,2.0105143282367153,-0.38449929077288447,4.783524978682848,2.1658669221988482,1.7216629695769743,-0.7101048204413503,0.8473984012280706,-0.1619123131620609,-0.4758002447614249,-0.42998258634220327,0.5412829355853829,1.5892312826899408
| 3,367
|
Actin filament based transport
| 9
| 10
| 2.160065
| 0.030768
|
Q8WXH0,Q9Y4I1,O00159,Q9UH99,Q9UM54,O43707,O43795,O94832,O00401
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
404,784,522,280,778,627,386,365,476
|
522,476,627,386,365,873,404,280,778,784
|
0.619171741197861,0.657768615715268,0.5412829355853829,0.7722057037721174,0.8099100211162025,0.38263514328382814,0.7722057037721174,1.031696165695717,0.46244619964697814,0.46244619964697814
| 3,367
|
Abnormal tissue metabolite concentration
| 6
| 15
| 2.15764
| 0.030956
|
P07602,P06280,P17900,O43933,P06865,P07686
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
34,67,107,15,84,119
|
2814,15,2448,67,84,34,119,633,107,1996,394,654,3020,222,854
|
-0.7580513366787757,4.320727255133443,-0.4758002447614249,2.554155818031785,2.3177928418789855,3.297852942116772,1.8193146884450921,0.5412829355853829,1.9155840365977252,-0.2058028271615026,0.7722057037721174,0.5412829355853829,-0.9536627270282968,1.2109881782657737,0.42266415546022
| 3,367
|
Transporter activity
| 43
| 144
| 2.157135
| 0.030995
|
Q8WTV0,Q6NT16,Q8IXU6,P08183,L0R6Q1,Q70HW3,Q9UBX3,Q9H4L5,Q9BSK2,Q8TB61,Q9NS69,Q99808,O43772,Q14849,Q15043,O15118,Q99595,Q9H0U3,Q9Y487,Q9HD20,Q9C0H2,O43676,Q93050,Q9BZF1,O96008,P21796,P28288,P30825,O75964,P16615,P04062,Q9HC21,O60830,P61916,P41440,P13073,Q13423,P17900,Q9UI12,P45880,P60059,Q9H2D1,Q9P0J0
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
5,7,8,132,251,13,142,147,274,270,26,158,42,49,315,46,178,322,186,185,56,58,62,192,308,309,197,201,89,211,210,360,96,99,102,232,233,107,249,115,241,123,261
|
251,2232,2305,440,1889,623,2510,46,1808,1295,58,2814,42,1639,96,2447,1980,1300,2582,630,2865,89,1719,1722,1895,690,1724,1304,2866,308,693,210,1215,1001,1896,2159,2710,132,2384,529,3338,1385,1556,1310,419,232,211,107,2529,864,2249,1732,2871,309,924,1562,1989,197,2533,1061,201,1394,2719,2875,1994,2591,102,115,449,3332,2922,1010,2398,641,2177,1140,806,1141,807,2781,645,2401,241,1011,871,99,2089,1069,1495,233,1150,3276,49,315,1584,3291,2275,594,7,2019,1250,460,13,8,1167,353,1683,270,5,972,62,889,839,765,178,158,2804,274,432,2133,192,56,322,2215,123,147,2218,1872,360,185,2631,26,261,142,512,1454,249,1285,1627,3296,1372,186,1376,2147
|
1.0679451413858796,-0.33934491131952355,-0.38449929077288447,0.6961379107980552,-0.1619123131620609,0.5412829355853829,-0.5219578544209845,2.8943684331092254,-0.11832544439901459,0.13707430384263497,2.754607952931739,-0.7580513366787757,3.0585160335120065,-0.032043988936474706,2.0730777150539357,-0.4758002447614249,-0.2058028271615026,0.13707430384263497,-0.5684611504154431,0.5412829355853829,-0.8063746087452964,2.227038925427992,-0.07503752950409251,-0.07503752950409251,-0.1619123131620609,0.5019846818620551,-0.07503752950409251,0.13707430384263497,-0.8063746087452964,0.9217383587835264,0.5019846818620551,1.2109881782657737,0.1786609951774037,0.30182221516229196,-0.1619123131620609,-0.29451413807445087,-0.6625285072121776,1.6557714498436458,-0.42998258634220327,0.619171741197861,-2.197689911987167,0.09521457913715693,0.010659648604851009,0.13707430384263497,0.7342826270023676,1.1398524773123389,1.2109881782657737,1.9155840365977252,-0.5219578544209845,0.38263514328382814,-0.33934491131952355,-0.07503752950409251,-0.8063746087452964,0.9217383587835264,0.342355682402477,0.010659648604851009,-0.2058028271615026,1.2813706494606423,-0.5219578544209845,0.26103110464403734,1.246272443990728,0.09521457913715693,-0.6625285072121776,-0.8063746087452964,-0.2058028271615026,-0.5684611504154431,2.0105143282367153,1.8515558846925475,0.6961379107980552,-2.024062737158297,-0.8550813717441338,0.30182221516229196,-0.42998258634220327,0.5412829355853829,-0.29451413807445087,0.2199786322467286,0.42266415546022,0.2199786322467286,0.42266415546022,-0.7101048204413503,0.5412829355853829,-0.42998258634220327,1.103996441331084,0.30182221516229196,0.38263514328382814,2.041867375489916,-0.25000179333226685,0.26103110464403734,0.05307774962454346,1.1398524773123389,0.2199786322467286,-1.523502876429464,2.8943684331092254,0.9217383587835264,0.010659648604851009,-1.632089162713181,-0.33934491131952355,0.580344223839915,4.910685979818012,-0.2058028271615026,0.1786609951774037,0.6961379107980552,4.433541950109594,4.889640280593516,0.2199786322467286,0.8473984012280706,-0.032043988936474706,1.031696165695717,5.895453047698817,0.342355682402477,2.669400494336479,0.38263514328382814,0.42266415546022,0.46244619964697814,1.3855706609057188,1.522027904662708,-0.7101048204413503,1.031696165695717,0.7342826270023676,-0.25000179333226685,1.3162849902600815,2.782782542710472,0.9217383587835264,-0.29451413807445087,1.7869199137107399,1.5892312826899408,-0.29451413807445087,-0.11832544439901459,0.8473984012280706,1.3510176219205223,-0.5684611504154431,3.802828202328214,1.0679451413858796,1.6225833456176855,0.657768615715268,0.09521457913715693,1.103996441331084,0.1786609951774037,0.010659648604851009,-1.632089162713181,0.13707430384263497,1.3510176219205223,0.13707430384263497,-0.25000179333226685
| 3,367
|
EF-hand domain pair [IPR011992]
| 13
| 47
| 2.153394
| 0.031288
|
Q14257,Q13813,Q9Y680,P31949,O75071,P80303,Q66K14,Q9BRK5,P07384,O43852,Q9UBC2,Q02818,Q03001
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
128,214,100,101,39,10,169,146,240,237,292,93,191
|
627,237,39,3325,630,690,2158,240,1002,1987,1648,1730,1390,2073,3248,101,1902,1063,332,2337,10,93,191,214,128,2735,2793,169,2019,1940,1856,880,2487,2424,883,1169,832,3217,668,146,1361,1791,292,3344,1285,565,100
|
0.5412829355853829,1.103996441331084,3.16587922270476,-1.9101855426565795,0.5412829355853829,0.5019846818620551,-0.29451413807445087,1.103996441331084,0.30182221516229196,-0.2058028271615026,-0.032043988936474706,-0.07503752950409251,0.09521457913715693,-0.25000179333226685,-1.416440179685344,2.0105143282367153,-0.1619123131620609,0.26103110464403734,0.884673610049861,-0.38449929077288447,4.783524978682848,2.1658669221988482,1.3162849902600815,1.2109881782657737,1.7216629695769743,-0.6625285072121776,-0.7101048204413503,1.419946185566603,-0.2058028271615026,-0.1619123131620609,-0.11832544439901459,0.38263514328382814,-0.4758002447614249,-0.42998258634220327,0.38263514328382814,0.2199786322467286,0.42266415546022,-1.3109065691871442,0.5412829355853829,1.5892312826899408,0.13707430384263497,-0.07503752950409251,0.995247055805408,-2.197689911987167,0.1786609951774037,0.619171741197861,2.041867375489916
| 3,367
|
Abnormal retinal vascular morphology
| 16
| 51
| 2.145492
| 0.031914
|
Q6P2Q9,P07602,P16278,Q9Y4P3,P04439,P10619,Q9UIG0,P35222,P17900,Q9NZJ7,P07686,P06865,Q8WYQ5,O60333,Q13510,Q96DF8
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
546,34,68,302,527,106,514,531,107,222,119,84,319,479,90,290
|
681,1207,1638,1979,1640,479,1300,792,2650,1721,527,84,34,119,2318,106,2768,2769,68,107,1479,2164,1391,576,531,2254,3289,2590,1994,2255,936,2880,2081,1405,1495,2406,1240,90,3284,1847,546,885,319,1090,969,2359,290,2627,222,514,302
|
0.5019846818620551,0.1786609951774037,-0.032043988936474706,-0.2058028271615026,-0.032043988936474706,0.657768615715268,0.13707430384263497,0.42266415546022,-0.6153160198205229,-0.07503752950409251,0.619171741197861,2.3177928418789855,3.297852942116772,1.8193146884450921,-0.38449929077288447,1.9473741733456051,-0.7101048204413503,-0.7101048204413503,2.554155818031785,1.9155840365977252,0.05307774962454346,-0.29451413807445087,0.09521457913715693,0.580344223839915,0.619171741197861,-0.33934491131952355,-1.632089162713181,-0.5684611504154431,-0.2058028271615026,-0.33934491131952355,0.342355682402477,-0.8063746087452964,-0.25000179333226685,0.09521457913715693,0.05307774962454346,-0.42998258634220327,0.1786609951774037,2.227038925427992,-1.5776059098511652,-0.11832544439901459,0.619171741197861,0.38263514328382814,0.9217383587835264,0.26103110464403734,0.342355682402477,-0.38449929077288447,0.995247055805408,-0.5684611504154431,1.2109881782657737,0.657768615715268,0.9585953053509725
| 3,367
|
Phospholipid metabolism
| 12
| 52
| 2.140651
| 0.032302
|
Q92604,Q8NCC3,Q10713,Q9BZF1,P42356,Q96N66,P35790,O95674,Q8IV08,Q8IY17,Q9NQZ5,Q9UG56
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
259,0,287,192,198,133,48,330,151,316,323,361
|
570,1975,624,2702,2313,330,2956,2325,2662,2388,48,932,198,1063,738,2922,2400,2001,1404,1571,287,2010,1073,1663,1335,1774,151,316,713,2023,403,1345,0,883,2202,3069,259,133,1176,3321,975,2804,2032,1099,192,1868,3198,2696,323,1706,361,566
|
0.580344223839915,-0.2058028271615026,0.5412829355853829,-0.6625285072121776,-0.38449929077288447,0.884673610049861,-0.9041772408267448,-0.38449929077288447,-0.6153160198205229,-0.42998258634220327,2.8943684331092254,0.342355682402477,1.2813706494606423,0.26103110464403734,0.46244619964697814,-0.8550813717441338,-0.42998258634220327,-0.2058028271615026,0.09521457913715693,0.010659648604851009,0.995247055805408,-0.2058028271615026,0.26103110464403734,-0.032043988936474706,0.13707430384263497,-0.07503752950409251,1.5557134250916398,0.9217383587835264,0.5019846818620551,-0.2058028271615026,0.7722057037721174,0.13707430384263497,6.753408671655479,0.38263514328382814,-0.29451413807445087,-1.0035370570387363,1.0679451413858796,1.6557714498436458,0.2199786322467286,-1.853811091154964,0.342355682402477,-0.7101048204413503,-0.2058028271615026,0.26103110464403734,1.3162849902600815,-0.11832544439901459,-1.2587149217723634,-0.6153160198205229,0.9217383587835264,-0.032043988936474706,0.8473984012280706,0.619171741197861
| 3,367
|
Abnormal retinal artery morphology
| 8
| 20
| 2.131523
| 0.033046
|
P07602,P16278,P10619,P17900,Q9NZJ7,P07686,P06865,Q13510
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
34,68,106,107,222,119,84,90
|
1638,1979,84,34,119,106,2769,68,107,1391,2254,2081,1405,90,3284,969,2359,222,514,302
|
-0.032043988936474706,-0.2058028271615026,2.3177928418789855,3.297852942116772,1.8193146884450921,1.9473741733456051,-0.7101048204413503,2.554155818031785,1.9155840365977252,0.09521457913715693,-0.33934491131952355,-0.25000179333226685,0.09521457913715693,2.227038925427992,-1.5776059098511652,0.342355682402477,-0.38449929077288447,1.2109881782657737,0.657768615715268,0.9585953053509725
| 3,367
|
Protease
| 23
| 87
| 2.130578
| 0.033124
|
Q9H3G5,P42785,P42892,Q9NZ08,Q9HB40,O14773,Q4J6C6,Q2T9J0,P81605,P55786,Q01804,P67812,Q70CQ2,O75976,Q99538,Q9NQH7,Q9H4L4,Q8TCT9,Q9UIQ6,P10619,O75844,P07384,Q16740
|
Functions
|
Protein Atlas Molecular function
|
protein_atlas_molecular_function
|
1,2,12,148,16,20,268,157,286,162,163,285,298,175,177,61,359,354,103,106,113,240,371
|
2813,3166,20,1469,1813,113,175,1128,390,240,3005,106,2657,2068,1730,485,2455,2456,2326,1062,1137,2780,2,12,2877,3261,2597,2882,580,806,869,3282,162,2542,285,286,451,163,1241,2613,2736,371,157,268,542,2479,3292,1249,298,2889,3194,1025,1169,354,1601,2120,971,1032,3316,1782,1352,2124,2849,1437,2209,3304,177,1699,1,1954,359,1791,16,61,3106,509,2573,148,2372,1188,103,619,1117,731,2052,1289,2645
|
-0.7580513366787757,-1.206907661975204,3.9953969719732,0.05307774962454346,-0.11832544439901459,1.8515558846925475,1.3855706609057188,0.2199786322467286,0.7722057037721174,1.103996441331084,-0.9536627270282968,1.9473741733456051,-0.6153160198205229,-0.25000179333226685,-0.07503752950409251,0.657768615715268,-0.4758002447614249,-0.4758002447614249,-0.38449929077288447,0.26103110464403734,0.2199786322467286,-0.7101048204413503,6.292167445838333,4.697545811150349,-0.8063746087452964,-1.4697807385854578,-0.5684611504154431,-0.8063746087452964,0.580344223839915,0.42266415546022,0.38263514328382814,-1.5776059098511652,1.4541462370669627,-0.5219578544209845,0.995247055805408,0.995247055805408,0.6961379107980552,1.4541462370669627,0.1786609951774037,-0.5684611504154431,-0.6625285072121776,0.8099100211162025,1.522027904662708,1.031696165695717,0.619171741197861,-0.4758002447614249,-1.632089162713181,0.1786609951774037,0.9585953053509725,-0.8063746087452964,-1.2587149217723634,0.30182221516229196,0.2199786322467286,0.8473984012280706,0.010659648604851009,-0.25000179333226685,0.342355682402477,0.30182221516229196,-1.7978135821100152,-0.07503752950409251,0.13707430384263497,-0.25000179333226685,-0.7580513366787757,0.09521457913715693,-0.29451413807445087,-1.7421936575233459,1.3855706609057188,-0.032043988936474706,6.653184264123767,-0.1619123131620609,0.8473984012280706,-0.07503752950409251,4.320727255133443,2.6979179668449453,-1.053799466605388,0.657768615715268,-0.5219578544209845,1.5892312826899408,-0.38449929077288447,0.2199786322467286,2.0105143282367153,0.580344223839915,0.26103110464403734,0.5019846818620551,-0.2058028271615026,0.1786609951774037,-0.5684611504154431
| 3,367
|
Cell surface
| 20
| 74
| 2.120901
| 0.03393
|
Q8WTV0,P08183,P42892,Q12846,P11279,Q00839,P11717,O15031,P01889,P09104,P05067,P55899,Q13641,Q8TCT9,P19022,Q9NWH9,P41440,Q08431,P02786,O75955
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
5,132,12,144,150,395,156,524,294,196,83,86,454,354,346,511,102,243,239,238
|
524,1378,1469,1000,1645,238,1130,2709,294,239,2316,527,83,2064,1896,3039,921,2159,132,2384,2711,196,2958,2525,1307,2161,1557,150,156,1986,1647,2068,1730,3120,346,1989,1393,2774,2823,1652,2328,3046,102,12,2535,1740,3282,1997,86,395,1659,243,144,2971,1325,1071,1577,2271,454,3018,747,706,2102,1341,354,5,2203,2750,2034,1364,511,2376,1970,1376
|
0.619171741197861,0.09521457913715693,0.05307774962454346,0.30182221516229196,-0.032043988936474706,1.103996441331084,0.2199786322467286,-0.6625285072121776,0.9585953053509725,1.103996441331084,-0.38449929077288447,0.619171741197861,2.3477816274627044,-0.25000179333226685,-0.1619123131620609,-1.0035370570387363,0.342355682402477,-0.29451413807445087,1.6557714498436458,-0.42998258634220327,-0.6625285072121776,1.2813706494606423,-0.9041772408267448,-0.5219578544209845,0.13707430384263497,-0.29451413807445087,0.010659648604851009,1.5557134250916398,1.522027904662708,-0.2058028271615026,-0.032043988936474706,-0.25000179333226685,-0.07503752950409251,-1.1044492003404638,0.8473984012280706,-0.2058028271615026,0.09521457913715693,-0.7101048204413503,-0.7580513366787757,-0.032043988936474706,-0.38449929077288447,-1.0035370570387363,2.0105143282367153,4.697545811150349,-0.5219578544209845,-0.07503752950409251,-1.5776059098511652,-0.2058028271615026,2.3177928418789855,0.7722057037721174,-0.032043988936474706,1.103996441331084,1.5892312826899408,-0.9041772408267448,0.13707430384263497,0.26103110464403734,0.010659648604851009,-0.33934491131952355,0.6961379107980552,-0.9536627270282968,0.46244619964697814,0.5019846818620551,-0.25000179333226685,0.13707430384263497,0.8473984012280706,5.895453047698817,-0.29451413807445087,-0.6625285072121776,-0.2058028271615026,0.13707430384263497,0.657768615715268,-0.38449929077288447,-0.1619123131620609,0.13707430384263497
| 3,367
|
Progressive neurologic deterioration
| 7
| 21
| 2.115537
| 0.034384
|
P54802,P07602,P16278,Q9NZJ7,Q9NPL8,P07686,P04062
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
65,34,68,222,87,119,210
|
2814,210,34,119,2524,633,68,1218,2164,576,802,65,1568,1745,287,2551,1509,1772,2210,87,222
|
-0.7580513366787757,1.2109881782657737,3.297852942116772,1.8193146884450921,-0.5219578544209845,0.5412829355853829,2.554155818031785,0.1786609951774037,-0.29451413807445087,0.580344223839915,0.42266415546022,2.640766626646635,0.010659648604851009,-0.07503752950409251,0.995247055805408,-0.5219578544209845,0.05307774962454346,-0.07503752950409251,-0.29451413807445087,2.3177928418789855,1.2109881782657737
| 3,367
|
Supranuclear gaze palsy
| 12
| 20
| 2.11531
| 0.034404
|
P07602,Q99720,Q9UEY8,P61916,Q9UDR5,Q96RL7,O15118,Q969N2,P35637,Q9NZJ7,Q96RR1,P04062
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
34,36,437,99,774,339,46,718,421,222,721,210
|
2233,1202,46,210,34,1476,736,421,1745,99,1923,945,1330,718,339,721,36,222,774,437
|
-0.33934491131952355,0.1786609951774037,2.8943684331092254,1.2109881782657737,3.297852942116772,0.05307774962454346,0.46244619964697814,0.7342826270023676,-0.07503752950409251,2.041867375489916,-0.1619123131620609,0.342355682402477,0.13707430384263497,0.5019846818620551,0.884673610049861,0.5019846818620551,3.218961116049131,1.2109881782657737,0.46244619964697814,0.7342826270023676
| 3,367
|
Abnormal circulating cholesterol concentration
| 17
| 33
| 2.112866
| 0.034612
|
P07602,P61916,Q8WXH0,Q10471,Q15800,Q14739,P50402,Q7Z5J4,Q9NZJ7,O75431,P42858,P34913,Q8N511,Q15392,P37268,Q15904,Q9UBM7
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
34,99,404,312,105,76,578,597,222,443,265,88,257,28,367,126,63
|
443,1816,2452,34,88,367,2876,265,3049,578,2832,646,99,1571,312,1072,2093,76,589,28,2098,105,126,597,2845,257,2846,404,1441,1537,222,63,1285
|
0.6961379107980552,-0.11832544439901459,-0.4758002447614249,3.297852942116772,2.2574227850195774,0.8099100211162025,-0.8063746087452964,1.031696165695717,-1.0035370570387363,0.580344223839915,-0.7580513366787757,0.5412829355853829,2.041867375489916,0.010659648604851009,0.9217383587835264,0.26103110464403734,-0.25000179333226685,2.4369781355796594,0.580344223839915,3.7046073923024947,-0.25000179333226685,1.9790170949571289,1.7543699026919297,0.580344223839915,-0.7580513366787757,1.0679451413858796,-0.7580513366787757,0.7722057037721174,0.09521457913715693,0.05307774962454346,1.2109881782657737,2.669400494336479,0.1786609951774037
| 3,367
|
Vacuolar transport
| 8
| 50
| 2.112649
| 0.034631
|
Q86VS8,Q14108,P07602,P20645,O15118,P13473,P11279,P11717
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
161,32,34,44,46,30,150,156
|
1713,1465,787,2511,46,1891,2817,1553,34,2712,150,156,30,44,1009,1907,1745,1011,1324,32,954,3133,547,161,1086,2690,2118,1349,2360,3348,1608,339,975,1696,2984,430,3073,2040,1043,2219,897,2044,222,2575,616,902,2049,3322,1710,412
|
-0.07503752950409251,0.05307774962454346,0.42266415546022,-0.5219578544209845,2.8943684331092254,-0.1619123131620609,-0.7580513366787757,0.010659648604851009,3.297852942116772,-0.6625285072121776,1.5557134250916398,1.522027904662708,3.6549956055948876,2.976917059317765,0.30182221516229196,-0.1619123131620609,-0.07503752950409251,0.30182221516229196,0.13707430384263497,3.5799366048175845,0.342355682402477,-1.1044492003404638,0.619171741197861,1.4881728202808266,0.26103110464403734,-0.6153160198205229,-0.25000179333226685,0.13707430384263497,-0.38449929077288447,-2.3153084893943583,0.010659648604851009,0.884673610049861,0.342355682402477,-0.032043988936474706,-0.9041772408267448,0.7342826270023676,-1.0035370570387363,-0.2058028271615026,0.30182221516229196,-0.29451413807445087,0.38263514328382814,-0.2058028271615026,1.2109881782657737,-0.5219578544209845,0.580344223839915,0.38263514328382814,-0.2058028271615026,-1.853811091154964,-0.032043988936474706,0.7722057037721174
| 3,367
|
Loss of speech
| 6
| 20
| 2.103142
| 0.035453
|
P07602,P61916,P17900,Q9NZJ7,O15118,P50897
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
34,99,107,222,46,29
|
208,46,2814,3229,2315,34,633,107,29,1829,1568,1745,644,99,945,1153,877,1790,222,1460
|
1.2109881782657737,2.8943684331092254,-0.7580513366787757,-1.3634818904670298,-0.38449929077288447,3.297852942116772,0.5412829355853829,1.9155840365977252,3.679843814797915,-0.11832544439901459,0.010659648604851009,-0.07503752950409251,0.5412829355853829,2.041867375489916,0.342355682402477,0.2199786322467286,0.38263514328382814,-0.07503752950409251,1.2109881782657737,0.09521457913715693
| 3,367
|
Arthritis
| 10
| 45
| 2.09182
| 0.036455
|
Q14108,P06280,Q14739,P01889,Q9NZ08,O75844,Q8WVQ1,Q13510,P04062,P60891
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
32,67,76,294,148,113,318,90,210,31
|
907,3034,3229,113,2519,294,1816,210,67,2385,1307,2819,1647,1391,2821,1650,1740,1228,2079,641,1400,2081,644,31,871,1571,2406,1410,90,32,76,1243,711,828,318,969,2359,1605,339,674,509,148,676,3080,1460
|
0.342355682402477,-1.0035370570387363,-1.3634818904670298,1.8515558846925475,-0.5219578544209845,0.9585953053509725,-0.11832544439901459,1.2109881782657737,2.554155818031785,-0.42998258634220327,0.13707430384263497,-0.7580513366787757,-0.032043988936474706,0.09521457913715693,-0.7580513366787757,-0.032043988936474706,-0.07503752950409251,0.1786609951774037,-0.25000179333226685,0.5412829355853829,0.09521457913715693,-0.25000179333226685,0.5412829355853829,3.6549956055948876,0.38263514328382814,0.010659648604851009,-0.42998258634220327,0.09521457913715693,2.227038925427992,3.5799366048175845,2.4369781355796594,0.1786609951774037,0.5019846818620551,0.42266415546022,0.9217383587835264,0.342355682402477,-0.38449929077288447,0.010659648604851009,0.884673610049861,0.5412829355853829,0.657768615715268,1.5892312826899408,0.5412829355853829,-1.0035370570387363,0.09521457913715693
| 3,367
|
External side of plasma membrane
| 7
| 22
| 2.088582
| 0.036745
|
P41440,P08183,P42892,P55899,Q08431,P02786,P11279
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
102,132,12,86,243,239,150
|
238,1130,2709,239,2316,2064,921,132,150,2068,1730,2774,102,12,2535,1740,86,243,747,2102,1341,2376
|
1.103996441331084,0.2199786322467286,-0.6625285072121776,1.103996441331084,-0.38449929077288447,-0.25000179333226685,0.342355682402477,1.6557714498436458,1.5557134250916398,-0.25000179333226685,-0.07503752950409251,-0.7101048204413503,2.0105143282367153,4.697545811150349,-0.5219578544209845,-0.07503752950409251,2.3177928418789855,1.103996441331084,0.46244619964697814,-0.25000179333226685,0.13707430384263497,-0.38449929077288447
| 3,367
|
Organophosphate ester transport
| 11
| 25
| 2.082809
| 0.037269
|
Q14108,Q9BZF1,Q9H2D1,P61916,Q8WTV0,P41440,P08183,Q9BSK2,Q8TB61,Q9HC21,Q99808
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
32,192,123,99,5,102,132,274,270,360,158
|
1639,1001,132,1310,419,924,3121,102,2922,99,2089,1410,32,2019,270,5,889,158,274,192,2215,123,360,1708,3296
|
-0.032043988936474706,0.30182221516229196,1.6557714498436458,0.13707430384263497,0.7342826270023676,0.342355682402477,-1.1044492003404638,2.0105143282367153,-0.8550813717441338,2.041867375489916,-0.25000179333226685,0.09521457913715693,3.5799366048175845,-0.2058028271615026,1.031696165695717,5.895453047698817,0.38263514328382814,1.522027904662708,1.031696165695717,1.3162849902600815,-0.29451413807445087,1.7869199137107399,0.8473984012280706,-0.032043988936474706,-1.632089162713181
| 3,367
|
metalloprotease
| 8
| 24
| 2.075386
| 0.037951
|
Q10713,P55786,Q9UIQ6,P42892,Q9NZ08,O75844,P02786,Q9NQH7
|
Functions
|
Panther Protein class
|
panther_protein_class
|
287,162,103,12,148,113,239,61
|
1469,1813,113,390,239,2657,2068,1820,2456,1394,12,580,162,287,542,2117,2124,1437,1699,61,2573,148,103,1289
|
0.05307774962454346,-0.11832544439901459,1.8515558846925475,0.7722057037721174,1.103996441331084,-0.6153160198205229,-0.25000179333226685,-0.11832544439901459,-0.4758002447614249,0.09521457913715693,4.697545811150349,0.580344223839915,1.4541462370669627,0.995247055805408,0.619171741197861,-0.25000179333226685,-0.25000179333226685,0.09521457913715693,-0.032043988936474706,2.6979179668449453,-0.5219578544209845,1.5892312826899408,2.0105143282367153,0.1786609951774037
| 3,367
|
Arteriosclerosis
| 6
| 17
| 2.073195
| 0.038154
|
P61916,P16278,O75844,O15118,P34913,Q13510
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
99,68,113,46,88,90
|
46,1644,113,1816,68,797,483,3151,88,1994,2876,99,1240,90,215,970,615
|
2.8943684331092254,-0.032043988936474706,1.8515558846925475,-0.11832544439901459,2.554155818031785,0.42266415546022,0.657768615715268,-1.1554855115344582,2.2574227850195774,-0.2058028271615026,-0.8063746087452964,2.041867375489916,0.1786609951774037,2.227038925427992,1.2109881782657737,0.342355682402477,0.580344223839915
| 3,367
|
Alcohol binding
| 7
| 17
| 2.072908
| 0.038181
|
Q9BZF1,Q14108,P61916,Q14849,Q9H4L5,O15118,P45880
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
192,32,99,49,147,46,115
|
1975,46,1812,2315,2710,309,3121,575,1061,532,115,99,32,49,192,2215,147
|
-0.2058028271615026,2.8943684331092254,-0.11832544439901459,-0.38449929077288447,-0.6625285072121776,0.9217383587835264,-1.1044492003404638,0.580344223839915,0.26103110464403734,0.619171741197861,1.8515558846925475,2.041867375489916,3.5799366048175845,2.8943684331092254,1.3162849902600815,-0.29451413807445087,1.5892312826899408
| 3,367
|
Steroid binding
| 8
| 22
| 2.064701
| 0.038951
|
Q14108,Q9BZF1,P61916,Q14849,Q9H4L5,O15118,P45880,P04062
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
32,192,99,49,147,46,115,210
|
1201,46,1808,2315,210,1215,2710,309,924,3121,1061,532,1994,115,99,32,49,839,2133,192,2215,147
|
0.1786609951774037,2.8943684331092254,-0.11832544439901459,-0.38449929077288447,1.2109881782657737,0.1786609951774037,-0.6625285072121776,0.9217383587835264,0.342355682402477,-1.1044492003404638,0.26103110464403734,0.619171741197861,-0.2058028271615026,1.8515558846925475,2.041867375489916,3.5799366048175845,2.8943684331092254,0.42266415546022,-0.25000179333226685,1.3162849902600815,-0.29451413807445087,1.5892312826899408
| 3,367
|
Biliary tract abnormality
| 8
| 29
| 2.061193
| 0.039285
|
Q14108,P07602,P09601,Q14739,O43933,Q9NZJ7,O96028,P04062
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
32,34,40,76,15,222,92,210
|
2814,15,690,92,1816,210,34,40,1647,633,3149,1062,2075,1996,287,453,1924,32,76,1509,970,971,1694,2627,2501,222,2946,854,1804
|
-0.7580513366787757,4.320727255133443,0.5019846818620551,2.1658669221988482,-0.11832544439901459,1.2109881782657737,3.297852942116772,3.1123997852653797,-0.032043988936474706,0.5412829355853829,-1.1554855115344582,0.26103110464403734,-0.25000179333226685,-0.2058028271615026,0.995247055805408,0.6961379107980552,-0.1619123131620609,3.5799366048175845,2.4369781355796594,0.05307774962454346,0.342355682402477,0.342355682402477,-0.032043988936474706,-0.5684611504154431,-0.4758002447614249,1.2109881782657737,-0.8550813717441338,0.42266415546022,-0.07503752950409251
| 3,367
|
Incoordination
| 11
| 70
| 2.055832
| 0.039799
|
Q6DKK2,P07602,Q9UJX6,Q9NR77,Q9NZJ7,O14773,P42858,O75503,Q13510,O00754,P04062
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
97,34,134,278,222,20,265,24,90,208,210
|
2233,208,20,1202,1293,2814,858,688,3325,24,912,2156,210,920,34,1386,1310,1818,633,2164,925,576,2168,2395,932,265,1484,2396,1995,1141,1745,2400,644,3157,1494,1919,2091,2408,287,945,90,2093,1761,1926,1245,2482,97,824,2484,1023,655,1424,970,1431,837,1608,721,1697,2210,1443,2627,2569,278,1185,222,2143,774,2144,134,905
|
-0.33934491131952355,1.2109881782657737,3.9953969719732,0.1786609951774037,0.13707430384263497,-0.7580513366787757,0.38263514328382814,0.5019846818620551,-1.9101855426565795,3.8514472696790003,0.342355682402477,-0.29451413807445087,1.2109881782657737,0.342355682402477,3.297852942116772,0.09521457913715693,0.13707430384263497,-0.11832544439901459,0.5412829355853829,-0.29451413807445087,0.342355682402477,0.580344223839915,-0.29451413807445087,-0.42998258634220327,0.342355682402477,1.031696165695717,0.05307774962454346,-0.42998258634220327,-0.2058028271615026,0.2199786322467286,-0.07503752950409251,-0.42998258634220327,0.5412829355853829,-1.1554855115344582,0.05307774962454346,-0.1619123131620609,-0.25000179333226685,-0.42998258634220327,0.995247055805408,0.342355682402477,2.227038925427992,-0.25000179333226685,-0.07503752950409251,-0.1619123131620609,0.1786609951774037,-0.4758002447614249,2.0730777150539357,0.42266415546022,-0.4758002447614249,0.30182221516229196,0.5412829355853829,0.09521457913715693,0.342355682402477,0.09521457913715693,0.42266415546022,0.010659648604851009,0.5019846818620551,-0.032043988936474706,-0.29451413807445087,0.09521457913715693,-0.5684611504154431,-0.5219578544209845,1.031696165695717,0.2199786322467286,1.2109881782657737,-0.25000179333226685,0.46244619964697814,-0.25000179333226685,1.6557714498436458,0.38263514328382814
| 3,367
|
Abnormality of head blood vessel
| 8
| 22
| 2.053482
| 0.040026
|
P07602,P16278,P10619,P17900,Q9NZJ7,P07686,P06865,Q13510
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
34,68,106,107,222,119,84,90
|
1202,1638,1979,84,34,119,106,2769,68,107,1391,2254,738,2081,1405,90,3284,969,2359,222,514,302
|
0.1786609951774037,-0.032043988936474706,-0.2058028271615026,2.3177928418789855,3.297852942116772,1.8193146884450921,1.9473741733456051,-0.7101048204413503,2.554155818031785,1.9155840365977252,0.09521457913715693,-0.33934491131952355,0.46244619964697814,-0.25000179333226685,0.09521457913715693,2.227038925427992,-1.5776059098511652,0.342355682402477,-0.38449929077288447,1.2109881782657737,0.657768615715268,0.9585953053509725
| 3,367
|
Myosin head, motor domain [IPR001609]
| 8
| 10
| 2.051796
| 0.040189
|
Q9Y4I1,O00159,P35580,Q7Z406,Q9UM54,O43795,O94832,P35579
|
Sequence
|
InterPro Domain
|
interpro_domain
|
784,522,447,711,778,386,365,737
|
522,386,365,737,447,873,1842,711,778,784
|
0.619171741197861,0.7722057037721174,0.8099100211162025,0.46244619964697814,0.6961379107980552,0.38263514328382814,-0.11832544439901459,0.5019846818620551,0.46244619964697814,0.46244619964697814
| 3,367
|
Sterol binding
| 7
| 17
| 2.051704
| 0.040198
|
Q9BZF1,Q14108,P61916,Q14849,Q9H4L5,O15118,P45880
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
192,32,99,49,147,46,115
|
46,2315,2710,309,924,3121,1061,532,115,99,32,49,839,2133,192,2215,147
|
2.8943684331092254,-0.38449929077288447,-0.6625285072121776,0.9217383587835264,0.342355682402477,-1.1044492003404638,0.26103110464403734,0.619171741197861,1.8515558846925475,2.041867375489916,3.5799366048175845,2.8943684331092254,0.42266415546022,-0.25000179333226685,1.3162849902600815,-0.29451413807445087,1.5892312826899408
| 3,367
|
Insertion of tail anchored proteins into the endoplasmic reticulum membrane
| 6
| 12
| 2.049087
| 0.040454
|
P09601,P51648,P05067,P60059,P46379,P50402
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
40,333,83,241,54,578
|
2814,2150,83,40,54,578,333,241,1747,585,2021,1708
|
-0.7580513366787757,-0.29451413807445087,2.3477816274627044,3.1123997852653797,2.782782542710472,0.580344223839915,0.884673610049861,1.103996441331084,-0.07503752950409251,0.580344223839915,-0.2058028271615026,-0.032043988936474706
| 3,367
|
Deafness
| 20
| 53
| 2.04596
| 0.04076
|
Q9NSV4,O43933,Q15031,O75648,Q9NR28,P60891,Q9Y276,Q7Z406,O95831,Q96RR1,Q9Y4A5,O95677,Q9UG56,O60313,P19447,Q9UM54,Q8N2K0,Q16740,O76024,P35579
|
Drugs and Diseases
|
Protein Atlas Disease involvement
|
protein_atlas_disease_involvement
|
675,15,397,389,291,31,854,711,417,721,729,692,361,209,483,778,659,371,364,737
|
2237,15,209,1296,2151,1472,389,364,692,417,2768,797,483,1732,1559,2872,865,3047,1134,737,1062,1319,2333,1139,1996,31,1912,1146,2786,1838,2181,1497,2791,2735,397,2551,1926,371,711,659,2199,1516,1777,1094,721,2215,291,1876,675,361,778,854,729
|
-0.33934491131952355,4.320727255133443,1.2109881782657737,0.13707430384263497,-0.29451413807445087,0.05307774962454346,0.7722057037721174,0.8099100211162025,0.5019846818620551,0.7342826270023676,-0.7101048204413503,0.42266415546022,0.657768615715268,-0.07503752950409251,0.010659648604851009,-0.8063746087452964,0.38263514328382814,-1.0035370570387363,0.2199786322467286,0.46244619964697814,0.26103110464403734,0.13707430384263497,-0.38449929077288447,0.2199786322467286,-0.2058028271615026,3.6549956055948876,-0.1619123131620609,0.2199786322467286,-0.7101048204413503,-0.11832544439901459,-0.29451413807445087,0.05307774962454346,-0.7101048204413503,-0.6625285072121776,0.7722057037721174,-0.5219578544209845,-0.1619123131620609,0.8099100211162025,0.5019846818620551,0.5412829355853829,-0.29451413807445087,0.05307774962454346,-0.07503752950409251,0.26103110464403734,0.5019846818620551,-0.29451413807445087,0.995247055805408,-0.11832544439901459,0.5412829355853829,0.8473984012280706,0.46244619964697814,0.42266415546022,0.5019846818620551
| 3,367
|
Status epilepticus
| 9
| 53
| 2.043797
| 0.040974
|
P07602,Q96F07,P42892,Q9H1C4,Q9NZJ7,Q9Y487,Q8IYB7,Q13510,Q15392
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
34,199,12,275,222,186,317,90,28
|
1635,1126,1720,2157,1215,34,2318,1556,1003,1990,736,2591,12,2175,3309,2723,2396,2830,1829,2080,2177,1066,696,3157,1404,1232,1494,812,2785,1752,2610,2788,90,1761,28,1077,317,199,973,2125,721,380,3294,275,1275,724,2504,2046,615,222,2143,902,186
|
-0.032043988936474706,0.2199786322467286,-0.07503752950409251,-0.29451413807445087,0.1786609951774037,3.297852942116772,-0.38449929077288447,0.010659648604851009,0.30182221516229196,-0.2058028271615026,0.46244619964697814,-0.5684611504154431,4.697545811150349,-0.29451413807445087,-1.7978135821100152,-0.6625285072121776,-0.42998258634220327,-0.7580513366787757,-0.11832544439901459,-0.25000179333226685,-0.29451413807445087,0.26103110464403734,0.5019846818620551,-1.1554855115344582,0.09521457913715693,0.1786609951774037,0.05307774962454346,0.42266415546022,-0.7101048204413503,-0.07503752950409251,-0.5684611504154431,-0.7101048204413503,2.227038925427992,-0.07503752950409251,3.7046073923024947,0.26103110464403734,0.9217383587835264,1.2813706494606423,0.342355682402477,-0.25000179333226685,0.5019846818620551,0.8099100211162025,-1.632089162713181,1.031696165695717,0.1786609951774037,0.5019846818620551,-0.4758002447614249,-0.2058028271615026,0.580344223839915,1.2109881782657737,-0.25000179333226685,0.38263514328382814,1.3510176219205223
| 3,367
|
Cellular hormone metabolic process
| 7
| 17
| 2.037627
| 0.041587
|
O95470,Q8NBN7,P42892,Q14849,Q15648,Q9HB40,Q8NBQ5
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
160,229,12,49,398,16,464
|
2152,160,3085,1061,12,1996,1401,49,398,651,493,229,464,1424,2210,16,1546
|
-0.29451413807445087,1.4881728202808266,-1.053799466605388,0.26103110464403734,4.697545811150349,-0.2058028271615026,0.09521457913715693,2.8943684331092254,0.7722057037721174,0.5412829355853829,0.657768615715268,1.1755156156311373,0.6961379107980552,0.09521457913715693,-0.29451413807445087,4.320727255133443,0.05307774962454346
| 3,367
|
Spectrin repeat [IPR002017]
| 7
| 10
| 2.035018
| 0.041849
|
Q13813,Q8WXH0,P46939,O43707,Q9UPN3,O75962,Q03001
|
Sequence
|
InterPro Repeat
|
interpro_repeat
|
214,404,332,627,565,573,191
|
1293,627,573,1002,332,744,191,214,404,565
|
0.13707430384263497,0.5412829355853829,0.580344223839915,0.30182221516229196,0.884673610049861,0.46244619964697814,1.3162849902600815,1.2109881782657737,0.7722057037721174,0.619171741197861
| 3,367
|
Endocytic vesicle
| 14
| 82
| 2.033591
| 0.041993
|
Q14108,P02786,Q8WTV0,P20645,Q16625,Q9H1C4,O00461,Q12846,Q9Y487,P13473,Q5KU26,P11279,P11717,Q93050
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
32,239,5,44,168,275,80,144,186,30,120,150,156,62
|
522,1052,476,80,787,1205,1295,733,3297,1471,2648,631,918,294,239,527,2868,794,1897,795,1307,1557,150,156,30,2322,2388,44,2774,1652,1314,448,2078,3155,2598,1907,2726,1142,2000,2676,2543,2001,1011,2968,2087,1232,1571,1324,144,873,1577,491,2184,32,369,2097,1929,2737,2477,168,2102,120,1508,2108,2559,2115,5,2491,62,761,975,2212,275,1361,777,2858,778,1710,186,988,1631,1888
|
0.619171741197861,0.26103110464403734,0.657768615715268,2.377641277448686,0.42266415546022,0.1786609951774037,0.13707430384263497,0.46244619964697814,-1.686951965968084,0.05307774962454346,-0.6153160198205229,0.5412829355853829,0.342355682402477,0.9585953053509725,1.103996441331084,0.619171741197861,-0.8063746087452964,0.42266415546022,-0.1619123131620609,0.42266415546022,0.13707430384263497,0.010659648604851009,1.5557134250916398,1.522027904662708,3.6549956055948876,-0.38449929077288447,-0.42998258634220327,2.976917059317765,-0.7101048204413503,-0.032043988936474706,0.13707430384263497,0.6961379107980552,-0.25000179333226685,-1.1554855115344582,-0.5684611504154431,-0.1619123131620609,-0.6625285072121776,0.2199786322467286,-0.2058028271615026,-0.6153160198205229,-0.5219578544209845,-0.2058028271615026,0.30182221516229196,-0.9041772408267448,-0.25000179333226685,0.1786609951774037,0.010659648604851009,0.13707430384263497,1.5892312826899408,0.38263514328382814,0.010659648604851009,0.657768615715268,-0.29451413807445087,3.5799366048175845,0.8099100211162025,-0.25000179333226685,-0.1619123131620609,-0.6625285072121776,-0.4758002447614249,1.419946185566603,-0.25000179333226685,1.8193146884450921,0.05307774962454346,-0.25000179333226685,-0.5219578544209845,-0.25000179333226685,5.895453047698817,-0.4758002447614249,2.669400494336479,0.46244619964697814,0.342355682402477,-0.29451413807445087,1.031696165695717,0.13707430384263497,0.46244619964697814,-0.7580513366787757,0.46244619964697814,-0.032043988936474706,1.3510176219205223,0.342355682402477,0.010659648604851009,-0.11832544439901459
| 3,367
|
Nuclear pore organization
| 9
| 13
| 2.023416
| 0.04303
|
P49790,P57740,Q9BTX1,Q92621,Q8WUM0,Q9NQC3,P52948,P12270,Q8WYP5
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
739,646,165,338,552,221,806,392,465
|
392,739,806,646,1589,882,1171,552,465,338,1523,165,221
|
0.7722057037721174,0.46244619964697814,0.42266415546022,0.5412829355853829,0.010659648604851009,0.38263514328382814,0.2199786322467286,0.619171741197861,0.6961379107980552,0.884673610049861,0.05307774962454346,1.4541462370669627,1.2109881782657737
| 3,367
|
Outer mitochondrial membrane protein complex
| 7
| 14
| 2.022951
| 0.043078
|
O96008,Q9BUR5,Q9Y512,Q16891,Q13505,O75431,Q9NS69
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
308,203,521,650,18,443,26
|
443,1719,308,2666,18,650,1509,1339,1085,203,26,726,1877,521
|
0.6961379107980552,-0.07503752950409251,0.9217383587835264,-0.6153160198205229,4.183049042361933,0.5412829355853829,0.05307774962454346,0.13707430384263497,0.26103110464403734,1.246272443990728,3.802828202328214,0.5019846818620551,-0.11832544439901459,0.657768615715268
| 3,367
|
Alpha/Beta hydrolase fold [IPR029058]
| 8
| 26
| 2.021891
| 0.043188
|
Q8NCC3,Q9H3G5,P42785,P10619,Q9HB40,Q9H6V9,P34913,P50897
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
0,1,2,106,16,19,88,29
|
3036,149,106,3171,2659,88,2876,2,3261,1740,29,268,2480,3194,659,0,3315,3195,3025,2128,1,19,16,1536,2902,3328
|
-1.0035370570387363,1.5557134250916398,1.9473741733456051,-1.206907661975204,-0.6153160198205229,2.2574227850195774,-0.8063746087452964,6.292167445838333,-1.4697807385854578,-0.07503752950409251,3.679843814797915,1.031696165695717,-0.4758002447614249,-1.2587149217723634,0.5412829355853829,6.753408671655479,-1.7978135821100152,-1.2587149217723634,-0.9536627270282968,-0.25000179333226685,6.653184264123767,4.042759805139087,4.320727255133443,0.05307774962454346,-0.8063746087452964,-1.9101855426565795
| 3,367
|
primary active transporter
| 6
| 16
| 2.016283
| 0.04377
|
O96008,Q9BUN8,P60059,Q9NS69,O60888,P16615
|
Functions
|
Panther Protein class
|
panther_protein_class
|
308,407,241,26,91,211
|
91,2448,1719,308,1215,392,211,864,740,241,1584,2106,407,1872,847,26
|
2.1965207527852213,-0.4758002447614249,-0.07503752950409251,0.9217383587835264,0.1786609951774037,0.7722057037721174,1.2109881782657737,0.38263514328382814,0.46244619964697814,1.103996441331084,0.010659648604851009,-0.25000179333226685,0.7722057037721174,-0.11832544439901459,0.42266415546022,3.802828202328214
| 3,367
|
Abnormal biliary tract morphology
| 7
| 25
| 2.014305
| 0.043978
|
Q14108,P07602,P09601,Q14739,O43933,Q9NZJ7,P04062
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
32,34,40,76,15,222,210
|
2814,15,1816,210,34,40,1647,633,3149,1062,2075,1996,287,453,32,76,1509,970,971,1694,2501,222,2946,854,1804
|
-0.7580513366787757,4.320727255133443,-0.11832544439901459,1.2109881782657737,3.297852942116772,3.1123997852653797,-0.032043988936474706,0.5412829355853829,-1.1554855115344582,0.26103110464403734,-0.25000179333226685,-0.2058028271615026,0.995247055805408,0.6961379107980552,3.5799366048175845,2.4369781355796594,0.05307774962454346,0.342355682402477,0.342355682402477,-0.032043988936474706,-0.4758002447614249,1.2109881782657737,-0.8550813717441338,0.42266415546022,-0.07503752950409251
| 3,367
|
Hypermetropia
| 28
| 59
| 2.012371
| 0.044181
|
Q9UJX6,Q96ST3,O14974,Q02809,Q8WWQ0,Q8WXI9,Q96L73,Q96A33,Q9H7D7,Q93008,Q71SY5,Q9Y4P3,P35222,Q96JM3,Q969N2,Q9ULH0,P27635,Q7Z5J4,A2RRP1,O00754,Q9H2P0,Q9UIG0,Q9H490,Q86V48,Q92878,Q7Z6Z7,Q9UHX1,Q15904
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
134,405,252,872,553,967,837,831,560,971,33,302,531,973,718,179,925,597,569,208,894,514,235,375,759,655,263,126
|
569,208,1202,252,2308,1979,2815,2383,1214,1985,1003,1821,925,531,2254,2591,1563,1066,1403,2602,1146,1405,872,1240,3284,126,2104,2019,2109,33,1023,597,655,375,1597,2846,553,967,1862,759,971,718,831,973,837,405,1526,1437,1443,894,235,560,1275,263,514,134,179,1881,302
|
0.580344223839915,1.2109881782657737,0.1786609951774037,1.0679451413858796,-0.38449929077288447,-0.2058028271615026,-0.7580513366787757,-0.42998258634220327,0.1786609951774037,-0.2058028271615026,0.30182221516229196,-0.11832544439901459,0.342355682402477,0.619171741197861,-0.33934491131952355,-0.5684611504154431,0.010659648604851009,0.26103110464403734,0.09521457913715693,-0.5684611504154431,0.2199786322467286,0.09521457913715693,0.38263514328382814,0.1786609951774037,-1.5776059098511652,1.7543699026919297,-0.25000179333226685,-0.2058028271615026,-0.25000179333226685,3.4530829773454683,0.30182221516229196,0.580344223839915,0.5412829355853829,0.8099100211162025,0.010659648604851009,-0.7580513366787757,0.619171741197861,0.342355682402477,-0.11832544439901459,0.46244619964697814,0.342355682402477,0.5019846818620551,0.42266415546022,0.342355682402477,0.42266415546022,0.7722057037721174,0.05307774962454346,0.09521457913715693,0.09521457913715693,0.38263514328382814,1.1398524773123389,0.619171741197861,0.1786609951774037,1.0679451413858796,0.657768615715268,1.6557714498436458,1.3855706609057188,-0.11832544439901459,0.9585953053509725
| 3,367
|
Carboxylic acid transport
| 7
| 29
| 2.010074
| 0.044423
|
P07602,P28288,P41440,P80404,Q9UBX3,P30825,Q9H2D1
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
34,197,102,75,142,201,123
|
1889,362,630,2450,1304,2316,2064,34,2384,1647,197,201,102,1141,807,2781,75,1495,1496,2188,2346,1584,1250,123,2218,1872,222,142,1285
|
-0.1619123131620609,0.8099100211162025,0.5412829355853829,-0.4758002447614249,0.13707430384263497,-0.38449929077288447,-0.25000179333226685,3.297852942116772,-0.42998258634220327,-0.032043988936474706,1.2813706494606423,1.246272443990728,2.0105143282367153,0.2199786322467286,0.42266415546022,-0.7101048204413503,2.4369781355796594,0.05307774962454346,0.05307774962454346,-0.29451413807445087,-0.38449929077288447,0.010659648604851009,0.1786609951774037,1.7869199137107399,-0.29451413807445087,-0.11832544439901459,1.2109881782657737,1.6225833456176855,0.1786609951774037
| 3,367
|
Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps
| 8
| 17
| 2.00996
| 0.044435
|
P19022,Q07065,P05067,Q08431,O43852,Q9BTY2,O76024,Q02818
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
346,225,83,243,237,153,364,93
|
237,364,83,921,1386,1648,2322,346,93,225,243,1497,1928,2793,1020,548,153
|
1.103996441331084,0.8099100211162025,2.3477816274627044,0.342355682402477,0.09521457913715693,-0.032043988936474706,-0.38449929077288447,0.8473984012280706,2.1658669221988482,1.1755156156311373,1.103996441331084,0.05307774962454346,-0.1619123131620609,-0.7101048204413503,0.30182221516229196,0.619171741197861,1.5557134250916398
| 3,367
|
Gait ataxia
| 24
| 68
| 2.007226
| 0.044726
|
Q9NR77,Q15031,O14773,Q8IV08,Q9H7D7,P15289,P35251,P42858,P55265,Q14108,Q10713,P07602,O15118,Q96RR1,Q8IY17,Q9NZJ7,O00754,O75962,P31040,Q96CW1,P41440,P07384,P04350,P19447
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
278,397,20,151,560,633,393,265,644,32,287,34,46,721,316,222,208,573,576,761,102,240,366,483
|
2233,208,20,1293,46,2814,2512,573,366,240,34,2768,1310,1818,633,923,797,483,2071,1218,2872,2664,925,3010,576,393,2395,102,265,2722,1995,1829,1996,1568,644,1746,812,2091,1837,287,1497,1924,945,2186,32,1153,397,2930,2482,1338,151,316,2981,761,1094,973,721,560,278,1537,1185,1186,222,2143,774,902,3270,1289
|
-0.33934491131952355,1.2109881782657737,3.9953969719732,0.13707430384263497,2.8943684331092254,-0.7580513366787757,-0.5219578544209845,0.580344223839915,0.8099100211162025,1.103996441331084,3.297852942116772,-0.7101048204413503,0.13707430384263497,-0.11832544439901459,0.5412829355853829,0.342355682402477,0.42266415546022,0.657768615715268,-0.25000179333226685,0.1786609951774037,-0.8063746087452964,-0.6153160198205229,0.342355682402477,-0.9536627270282968,0.580344223839915,0.7722057037721174,-0.42998258634220327,2.0105143282367153,1.031696165695717,-0.6625285072121776,-0.2058028271615026,-0.11832544439901459,-0.2058028271615026,0.010659648604851009,0.5412829355853829,-0.07503752950409251,0.42266415546022,-0.25000179333226685,-0.11832544439901459,0.995247055805408,0.05307774962454346,-0.1619123131620609,0.342355682402477,-0.29451413807445087,3.5799366048175845,0.2199786322467286,0.7722057037721174,-0.8550813717441338,-0.4758002447614249,0.13707430384263497,1.5557134250916398,0.9217383587835264,-0.9041772408267448,0.46244619964697814,0.26103110464403734,0.342355682402477,0.5019846818620551,0.619171741197861,1.031696165695717,0.05307774962454346,0.2199786322467286,0.2199786322467286,1.2109881782657737,-0.25000179333226685,0.46244619964697814,0.38263514328382814,-1.4697807385854578,0.1786609951774037
| 3,367
|
Endoplasmic reticulum golgi intermediate compartment
| 7
| 45
| 2.003965
| 0.045074
|
P80303,O15260,P24390,Q9Y282,Q08379,Q02818,Q15904
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
10,14,47,25,212,93,126
|
1378,14,1715,1295,2648,689,921,2958,47,2774,2328,868,1010,1906,1139,2399,869,2465,10,93,212,452,1325,585,456,1928,126,1508,3312,257,1686,665,3070,889,2034,2294,1037,1187,2047,2144,566,25,679,1199,1971
|
0.09521457913715693,4.34342738654226,-0.07503752950409251,0.13707430384263497,-0.6153160198205229,0.5019846818620551,0.342355682402477,-0.9041772408267448,2.8943684331092254,-0.7101048204413503,-0.38449929077288447,0.38263514328382814,0.30182221516229196,-0.1619123131620609,0.2199786322467286,-0.42998258634220327,0.38263514328382814,-0.4758002447614249,4.783524978682848,2.1658669221988482,1.2109881782657737,0.6961379107980552,0.13707430384263497,0.580344223839915,0.6961379107980552,-0.1619123131620609,1.7543699026919297,0.05307774962454346,-1.7978135821100152,1.0679451413858796,-0.032043988936474706,0.5412829355853829,-1.0035370570387363,0.38263514328382814,-0.2058028271615026,-0.33934491131952355,0.30182221516229196,0.2199786322467286,-0.2058028271615026,-0.25000179333226685,0.619171741197861,3.8271781683887824,0.5412829355853829,0.2199786322467286,-0.1619123131620609
| 3,367
|
Lipid transporter activity
| 7
| 20
| 2.00326
| 0.045149
|
Q9BZF1,P61916,P08183,P17900,Q14849,Q9H4L5,O15118
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
192,99,132,107,49,147,46
|
2510,46,132,1556,107,924,197,1061,2922,99,2089,49,1250,889,839,2133,192,2215,147,3296
|
-0.5219578544209845,2.8943684331092254,1.6557714498436458,0.010659648604851009,1.9155840365977252,0.342355682402477,1.2813706494606423,0.26103110464403734,-0.8550813717441338,2.041867375489916,-0.25000179333226685,2.8943684331092254,0.1786609951774037,0.38263514328382814,0.42266415546022,-0.25000179333226685,1.3162849902600815,-0.29451413807445087,1.5892312826899408,-1.632089162713181
| 3,367
|
Clumsiness
| 7
| 22
| 1.992219
| 0.046347
|
P07602,Q9NR77,Q9NZJ7,O14773,O75503,Q13510,O00754
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
34,278,222,20,24,90,208
|
208,20,1202,2814,858,24,920,34,633,576,2168,265,2091,945,90,1926,2482,824,721,278,222,774
|
1.2109881782657737,3.9953969719732,0.1786609951774037,-0.7580513366787757,0.38263514328382814,3.8514472696790003,0.342355682402477,3.297852942116772,0.5412829355853829,0.580344223839915,-0.29451413807445087,1.031696165695717,-0.25000179333226685,0.342355682402477,2.227038925427992,-0.1619123131620609,-0.4758002447614249,0.42266415546022,0.5019846818620551,1.031696165695717,1.2109881782657737,0.46244619964697814
| 3,367
|
Intrinsic component of mitochondrial membrane
| 15
| 39
| 1.988884
| 0.046714
|
P50416,O60830,O96008,Q9BPX6,Q9Y2R0,Q9BUR5,O14925,Q9Y512,Q16891,Q99595,Q13505,O75431,O75880,Q9HC21,Q9UG56
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
579,96,308,668,110,203,623,521,650,178,18,443,481,360,361
|
623,858,96,443,481,1719,1304,308,1310,2666,579,1069,18,1927,750,650,1335,1509,1339,1085,1856,880,1683,178,668,203,1950,1871,1872,2368,360,2631,726,1877,361,1284,110,1289,521
|
0.5412829355853829,0.38263514328382814,2.0730777150539357,0.6961379107980552,0.657768615715268,-0.07503752950409251,0.13707430384263497,0.9217383587835264,0.13707430384263497,-0.6153160198205229,0.580344223839915,0.26103110464403734,4.183049042361933,-0.1619123131620609,0.46244619964697814,0.5412829355853829,0.13707430384263497,0.05307774962454346,0.13707430384263497,0.26103110464403734,-0.11832544439901459,0.38263514328382814,-0.032043988936474706,1.3855706609057188,0.5412829355853829,1.246272443990728,-0.1619123131620609,-0.11832544439901459,-0.11832544439901459,-0.38449929077288447,0.8473984012280706,-0.5684611504154431,0.5019846818620551,-0.11832544439901459,0.8473984012280706,0.1786609951774037,1.9155840365977252,0.1786609951774037,0.657768615715268
| 3,367
|
Abnormality of the skull base
| 13
| 68
| 1.987735
| 0.046841
|
P49748,Q9UJX6,P80404,Q14739,Q9H490,Q12768,Q9UHX1,Q9NPL8,Q9Y487,Q2M1P5,O00754,O43505,Q9UBM7
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
130,134,75,76,235,127,263,87,186,217,208,122,63
|
3184,208,1054,1202,2953,3147,122,1468,2058,2863,1379,2383,1471,1720,1057,346,1732,1559,2390,1392,2875,2591,738,3309,130,1995,805,1568,1746,2000,1911,1832,75,287,127,1238,2181,747,76,589,2347,217,2481,1935,1159,1023,1346,1423,758,1862,971,1432,1783,1606,837,765,2624,1443,1616,2899,235,87,63,263,902,134,186,3300
|
-1.2587149217723634,1.2109881782657737,0.26103110464403734,0.1786609951774037,-0.9041772408267448,-1.1554855115344582,1.7869199137107399,0.05307774962454346,-0.25000179333226685,-0.8063746087452964,0.09521457913715693,-0.42998258634220327,0.05307774962454346,-0.07503752950409251,0.26103110464403734,0.8473984012280706,-0.07503752950409251,0.010659648604851009,-0.42998258634220327,0.09521457913715693,-0.8063746087452964,-0.5684611504154431,0.46244619964697814,-1.7978135821100152,1.6887973998936312,-0.2058028271615026,0.42266415546022,0.010659648604851009,-0.07503752950409251,-0.2058028271615026,-0.1619123131620609,-0.11832544439901459,2.4369781355796594,0.995247055805408,1.7216629695769743,0.1786609951774037,-0.29451413807445087,0.46244619964697814,2.4369781355796594,0.580344223839915,-0.38449929077288447,1.2109881782657737,-0.4758002447614249,-0.1619123131620609,0.2199786322467286,0.30182221516229196,0.13707430384263497,0.09521457913715693,0.46244619964697814,-0.11832544439901459,0.342355682402477,0.09521457913715693,-0.07503752950409251,0.010659648604851009,0.42266415546022,0.46244619964697814,-0.5684611504154431,0.09521457913715693,0.010659648604851009,-0.8063746087452964,1.1398524773123389,2.3177928418789855,2.669400494336479,1.0679451413858796,0.38263514328382814,1.6557714498436458,1.3510176219205223,-1.686951965968084
| 3,367
|
Subsets and Splits
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