term
stringlengths
2
121
overlap
int64
6
281
setsize
int64
7
499
score
float64
1.96
10.6
pval
float64
0
0.05
edge
stringlengths
41
1.97k
type
stringclasses
5 values
subtype
stringclasses
24 values
subtype_key
stringclasses
24 values
edge_idxs
stringlengths
11
1.17k
ann_idxs
stringlengths
19
2.31k
ann_vals
stringlengths
124
9.94k
sig_size
int64
2.2k
3.73k
Myosin complex
8
12
2.771293
0.005583
Q13459,Q12965,O94832,O43795,Q9Y4I1,P35580,P60660,P35579
Localization
GO Cellular component
msigdb_gocc
262,261,319,206,287,387,217,245
407,206,319,245,387,217,261,262,2191,1958,890,287
0.7933537558921767,1.249292736644776,0.9478531474732188,1.1373892537486945,0.8322262551325478,1.212138715175788,1.099790142352336,1.099790142352336,-0.3248598804887178,-0.1940306860173823,0.3949453920319386,1.0620389315076852
3,367
Ceramide metabolic process
7
18
2.767279
0.005653
P07686,Q13510,Q96G23,P17900,P06865,P06280,Q8NCC3
Processes and pathways
GO Biological process
msigdb_gobp
103,104,143,46,47,23,60
1025,1659,668,841,23,47,103,46,3333,2164,2268,645,104,2460,60,143,202,493
0.27179356591045745,-0.06480379588709152,0.51638636702171,0.3949453920319386,3.860476447122193,2.9518057266228475,1.719723884747831,3.014617485988229,-2.1124650811200967,-0.3248598804887178,-0.36882191692968064,0.5564909583357176,1.719723884747831,-0.4572697498231123,2.3368292667835435,1.5054130123499248,1.2863020037686608,0.7150999985878068
3,367
Amyloid precursor protein metabolic process
6
19
2.767191
0.005654
Q15392,P42574,P62942,Q9NQC3,P27695,Q92542
Processes and pathways
GO Biological process
msigdb_gobp
0,260,75,384,304,159
2425,2338,304,361,260,2085,1052,75,2962,1402,2526,1405,0,159,2885,1428,1429,384,2051
-0.4572697498231123,-0.412958796825298,0.9860724317343753,0.8709321917690549,1.099790142352336,-0.2810734678085235,0.27179356591045745,2.0670777141599412,-0.8179346882917339,0.06279828060143189,-0.5017540153159744,0.06279828060143189,9.266342596549883,1.4329258820598159,-0.7267490661171271,0.06279828060143189,0.06279828060143189,0.8709321917690549,-0.23746346936348223
3,367
Vesicle cytoskeletal trafficking
10
21
2.766023
0.005674
O14617,O00203,Q14204,P42858,O00159,Q12965,O94832,O43795,Q9Y4I1,P27695
Processes and pathways
GO Biological process
msigdb_gobp
183,408,328,100,407,261,319,206,287,304
407,408,1369,183,1302,206,319,1744,304,2166,100,415,2522,2524,261,328,1515,890,2324,834,287
0.7933537558921767,0.7933537558921767,0.06279828060143189,1.3231682601538646,0.10496721166567786,1.249292736644776,0.9478531474732188,-0.10770002139860704,0.9860724317343753,-0.3248598804887178,1.7549981936289338,0.7933537558921767,-0.5017540153159744,-0.5017540153159744,1.099790142352336,0.9478531474732188,0.020446217421404334,0.3949453920319386,-0.36882191692968064,0.4356160170646649,1.0620389315076852
3,367
Hydrops fetalis
12
45
2.764752
0.005697
P10619,Q14739,Q07020,Q13510,P16278,P62899,P61313,P18077,P62847,Q8NCM8,P42766,P61353
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
68,38,134,104,164,198,74,165,197,181,177,275
1560,1167,1459,1306,2654,841,1378,1230,68,1231,164,165,1177,2259,3095,2354,177,2956,292,3227,597,2176,851,910,74,275,1054,680,855,197,1681,198,2264,2091,2268,134,104,38,181,2471,924,1530,3291,1719,2897
-0.022088097488964575,0.18875209347989597,0.020446217421404334,0.10496721166567786,-0.5912394888767456,0.3949453920319386,0.06279828060143189,0.14695211780225223,2.1690444425785262,0.14695211780225223,1.3964785412072227,1.3964785412072227,0.18875209347989597,-0.36882191692968064,-1.0023112020703986,-0.412958796825298,1.3598932144259221,-0.8179346882917339,1.0241336866990407,-1.2838097038521317,0.5964120554641071,-0.3248598804887178,0.3949453920319386,0.3540841185619894,2.0670777141599412,1.0620389315076852,0.27179356591045745,0.51638636702171,0.3949453920319386,1.2863020037686608,-0.06480379588709152,1.2863020037686608,-0.36882191692968064,-0.2810734678085235,-0.36882191692968064,1.5414559276361184,1.719723884747831,3.1701628794451158,1.3598932144259221,-0.4572697498231123,0.3540841185619894,0.020446217421404334,-1.52282763066264,-0.06480379588709152,-0.7267490661171271
3,367
Lipid biosynthesis
9
55
2.763438
0.00572
Q15392,Q9UBM7,Q14739,Q15125,Q96N66,Q96G23,Q92604,Q16850,P37268
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
0,1,38,7,144,143,223,157,30
2060,1163,954,1452,411,2247,463,2070,467,2731,3333,635,30,2000,215,793,597,1114,1762,1679,2807,3339,1185,1118,645,1252,38,7,3075,984,0,2024,446,157,1193,557,1269,2758,3249,485,223,3322,143,144,3050,881,1639,1962,3142,2312,336,767,1,622,2713
-0.2810734678085235,0.18875209347989597,0.31303318522898527,0.020446217421404334,0.7933537558921767,-0.36882191692968064,0.7150999985878068,-0.2810734678085235,0.7150999985878068,-0.6362392226649662,-2.1124650811200967,0.5564909583357176,3.4751842548839553,-0.23746346936348223,1.212138715175788,0.4356160170646649,0.5964120554641071,0.23036622014532987,-0.10770002139860704,-0.06480379588709152,-0.6814093200124656,-2.3139063625418146,0.18875209347989597,0.23036622014532987,0.5564909583357176,0.14695211780225223,3.1701628794451158,5.347423495313898,-0.9559681035265681,0.31303318522898527,9.266342596549883,-0.23746346936348223,0.754312439228042,1.4329258820598159,0.18875209347989597,0.6361522503407359,0.14695211780225223,-0.6362392226649662,-1.3312935370263337,0.7150999985878068,1.212138715175788,-1.8148607923698326,1.5054130123499248,1.5054130123499248,-0.9097905400273109,0.3949453920319386,-0.022088097488964575,-0.1940306860173823,-1.0488191777371687,-0.36882191692968064,0.9478531474732188,0.4760956266149155,6.354521266861696,0.5964120554641071,-0.5912394888767456
3,367
Entry into host
8
30
2.75684
0.005836
P02786,Q9BTY2,Q8WTV0,O15118,P35613,P11279,Q14108,O14786
Processes and pathways
GO Biological process
msigdb_gobp
67,4,110,81,305,90,27,127
127,81,2424,67,1309,1826,1037,1464,2159,1466,90,542,3091,2949,3242,305,2955,1051,2525,27,327,1253,2677,110,1353,1633,4,2226,713,775
1.5773671103553362,2.032866242545018,-0.4572697498231123,2.202814512277326,0.10496721166567786,-0.15077592925131486,0.27179356591045745,0.020446217421404334,-0.3248598804887178,0.020446217421404334,1.8948765913387664,0.6361522503407359,-1.0023112020703986,-0.8179346882917339,-1.3312935370263337,0.9860724317343753,-0.8179346882917339,0.27179356591045745,-0.5017540153159744,3.6248188309031892,0.9478531474732188,0.14695211780225223,-0.5912394888767456,1.6843250163853651,0.10496721166567786,-0.022088097488964575,5.6569309364282425,-0.3248598804887178,0.51638636702171,0.4760956266149155
3,367
Abnormal pharynx morphology
10
37
2.746731
0.006019
P41229,Q13510,P16278,P15586,P13051,Q93008,P01889,P54802,Q15833,P60891
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
33,104,164,13,163,311,84,54,420,24
2573,1822,3146,1558,2722,1825,84,2582,163,13,164,2076,636,33,2513,1918,735,599,736,54,2008,24,1846,2268,2963,1120,104,420,3246,1791,2197,2549,311,2550,1799,1007,426
-0.546410842239735,-0.15077592925131486,-1.0954913801193207,-0.022088097488964575,-0.6362392226649662,-0.15077592925131486,1.9985415804284918,-0.546410842239735,1.3964785412072227,4.896921049154351,1.3964785412072227,-0.2810734678085235,0.5564909583357176,3.3236578103542245,-0.5017540153159744,-0.1940306860173823,0.4760956266149155,0.5964120554641071,0.4760956266149155,2.664757267155283,-0.23746346936348223,3.8312646321143324,-0.15077592925131486,-0.36882191692968064,-0.8179346882917339,0.23036622014532987,1.719723884747831,0.7933537558921767,-1.3312935370263337,-0.10770002139860704,-0.3248598804887178,-0.5017540153159744,0.9860724317343753,-0.5017540153159744,-0.10770002139860704,0.31303318522898527,0.7933537558921767
3,367
Organic anion transport
16
39
2.742003
0.006107
P80404,O95563,P53985,P11166,P30825,P28288,P07602,P53007,Q15041,Q99808,Q9H2D1,P14174,Q9UBX3,Q9HC21,Q9NZJ7,O14745
Processes and pathways
GO Biological process
msigdb_gobp
65,462,294,466,259,258,17,510,519,225,490,116,495,192,162,433
433,1373,2848,1984,2428,462,2155,788,1309,17,1464,466,1040,789,116,258,259,2355,510,294,2916,65,1248,645,519,1779,2677,2606,1696,561,225,490,2976,2212,192,162,495,2713,2567
0.754312439228042,0.06279828060143189,-0.7267490661171271,-0.23746346936348223,-0.4572697498231123,0.7150999985878068,-0.3248598804887178,0.4356160170646649,0.10496721166567786,4.3750256940936305,0.020446217421404334,0.7150999985878068,0.27179356591045745,0.4356160170646649,1.613148049789865,1.099790142352336,1.099790142352336,-0.412958796825298,0.6757140740040977,1.0241336866990407,-0.7722577547913748,2.2364769766120918,0.14695211780225223,0.5564909583357176,0.6757140740040977,-0.10770002139860704,-0.5912394888767456,-0.546410842239735,-0.06480379588709152,0.6361522503407359,1.212138715175788,0.7150999985878068,-0.8179346882917339,-0.3248598804887178,1.3231682601538646,1.4329258820598159,0.7150999985878068,-0.5912394888767456,-0.5017540153159744
3,367
Lipid homeostasis
8
23
2.738457
0.006173
Q5BJF2,Q8WTV0,Q9NQC3,O15260,O15118,Q9Y6C9,Q6YHU6,P61916
Processes and pathways
GO Biological process
msigdb_gobp
10,110,384,49,81,151,279,25
2497,81,1101,49,633,1175,1234,1579,361,25,1118,645,2674,10,690,279,110,2763,1003,384,831,3115,151
-0.5017540153159744,2.032866242545018,0.23036622014532987,2.793240616952005,0.5564909583357176,0.18875209347989597,0.14695211780225223,-0.022088097488964575,0.8709321917690549,3.772633277255873,0.23036622014532987,0.5564909583357176,-0.5912394888767456,5.216435956950591,0.51638636702171,1.0620389315076852,1.6843250163853651,-0.6362392226649662,0.31303318522898527,0.8709321917690549,0.4356160170646649,-1.0023112020703986,1.469236846394831
3,367
Incoordination
11
70
2.731856
0.006298
O14773,O75503,P42858,Q8TC12,Q13510,O00754,P27635,Q13501,P07602,O75165,Q9NZJ7
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
2,3,100,172,104,44,195,234,17,300,162
2718,44,2,497,779,1301,1901,300,3277,3,1031,2337,841,730,17,1667,1040,1312,413,2349,195,847,1997,2861,2354,100,1839,2084,2446,510,2262,2176,1590,2741,3154,515,2920,1599,1772,234,104,1123,328,2674,2096,1862,2028,1613,919,1866,610,172,1205,2827,996,1074,1075,1141,1714,2629,2211,2049,1721,2220,162,1896,1442,660,889,1368
-0.6362392226649662,3.014617485988229,5.884770299255648,0.6757140740040977,0.4356160170646649,0.10496721166567786,-0.1940306860173823,0.9860724317343753,-1.4747054833332776,5.682423722639393,0.27179356591045745,-0.412958796825298,0.3949453920319386,0.4760956266149155,4.3750256940936305,-0.06480379588709152,0.27179356591045745,0.10496721166567786,0.7933537558921767,-0.412958796825298,1.2863020037686608,0.3949453920319386,-0.23746346936348223,-0.7267490661171271,-0.412958796825298,1.7549981936289338,-0.15077592925131486,-0.2810734678085235,-0.4572697498231123,0.6757140740040977,-0.36882191692968064,-0.3248598804887178,-0.022088097488964575,-0.6362392226649662,-1.0954913801193207,0.6757140740040977,-0.7722577547913748,-0.022088097488964575,-0.10770002139860704,1.1748381597601374,1.719723884747831,0.23036622014532987,0.9478531474732188,-0.5912394888767456,-0.2810734678085235,-0.15077592925131486,-0.23746346936348223,-0.022088097488964575,0.3540841185619894,-0.15077592925131486,0.5964120554641071,1.3964785412072227,0.18875209347989597,-0.6814093200124656,0.31303318522898527,0.27179356591045745,0.27179356591045745,0.23036622014532987,-0.06480379588709152,-0.546410842239735,-0.3248598804887178,-0.23746346936348223,-0.06480379588709152,-0.3248598804887178,1.4329258820598159,-0.15077592925131486,0.06279828060143189,0.5564909583357176,0.3949453920319386,0.10496721166567786
3,367
Immunoglobulin-like domain superfamily [IPR036179]
7
14
2.718261
0.006563
P10321,P04439,P55899,Q9BX67,P01889,P35613,P43121
Sequence
InterPro Superfamily
interpro_homologous_superfamily
213,73,43,313,84,305,342
1558,358,84,73,213,305,342,43,1855,1948,1625,313,3209,775
-0.022088097488964575,0.8709321917690549,1.9985415804284918,2.1011771507196184,1.212138715175788,0.9860724317343753,0.909473770504105,3.0458947300580568,-0.15077592925131486,-0.1940306860173823,-0.022088097488964575,0.9860724317343753,-1.1893259001279373,0.4760956266149155
3,367
Immunoglobulin-like domain [IPR007110]
7
14
2.718261
0.006563
P10321,P04439,P55899,Q9BX67,P01889,P35613,P43121
Sequence
InterPro Domain
interpro_domain
213,73,43,313,84,305,342
1558,358,84,73,213,305,342,43,1855,1948,1625,313,3209,775
-0.022088097488964575,0.8709321917690549,1.9985415804284918,2.1011771507196184,1.212138715175788,0.9860724317343753,0.909473770504105,3.0458947300580568,-0.15077592925131486,-0.1940306860173823,-0.022088097488964575,0.9860724317343753,-1.1893259001279373,0.4760956266149155
3,367
Transition metal ion homeostasis
10
24
2.716383
0.0066
O14617,Q8N511,O00203,Q9H3K6,Q658P3,P02786,P04179,P05067,Q15904,Q15043
Processes and pathways
GO Biological process
msigdb_gobp
183,421,408,267,36,67,464,14,48,330
408,183,1901,1902,1375,2151,2902,67,464,14,1908,544,1476,1578,3177,737,2376,2526,330,48,36,421,267,1295
0.7933537558921767,1.3231682601538646,-0.1940306860173823,-0.1940306860173823,0.06279828060143189,-0.3248598804887178,-0.7722577547913748,2.202814512277326,0.7150999985878068,4.815860976496678,-0.1940306860173823,0.6361522503407359,0.020446217421404334,-0.022088097488964575,-1.142327166182432,0.4760956266149155,-0.412958796825298,-0.5017540153159744,0.9478531474732188,2.888645998928826,3.201023198065498,0.7933537558921767,1.099790142352336,0.14695211780225223
3,367
Gait ataxia
11
68
2.714582
0.006636
P35251,O14773,P42858,O00754,P27635,Q13501,P07602,O15118,Q8IV08,Q14108,Q9NZJ7
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
153,2,100,44,195,234,17,81,51,27,162
2718,44,2,779,81,1301,1900,358,465,2586,17,1987,1040,1312,413,439,1042,671,2162,3240,1832,1994,195,2439,847,153,2861,2355,100,2083,2446,1325,2363,1589,1590,972,3301,2920,2182,1772,3132,1119,234,1251,27,1406,802,1189,1862,2756,51,2610,2394,564,1522,2301,1075,268,1721,2633,2220,577,162,1896,1442,1014,2894,2493
-0.6362392226649662,3.014617485988229,5.884770299255648,0.4356160170646649,2.032866242545018,0.10496721166567786,-0.1940306860173823,0.8709321917690549,0.7150999985878068,-0.546410842239735,4.3750256940936305,-0.23746346936348223,0.27179356591045745,0.10496721166567786,0.7933537558921767,0.754312439228042,0.27179356591045745,0.51638636702171,-0.3248598804887178,-1.3312935370263337,-0.15077592925131486,-0.23746346936348223,1.2863020037686608,-0.4572697498231123,0.3949453920319386,1.4329258820598159,-0.7267490661171271,-0.412958796825298,1.7549981936289338,-0.2810734678085235,-0.4572697498231123,0.10496721166567786,-0.412958796825298,-0.022088097488964575,-0.022088097488964575,0.31303318522898527,-1.6195456688999854,-0.7722577547913748,-0.3248598804887178,-0.10770002139860704,-1.0488191777371687,0.23036622014532987,1.1748381597601374,0.14695211780225223,3.6248188309031892,0.06279828060143189,0.4356160170646649,0.18875209347989597,-0.15077592925131486,-0.6362392226649662,2.7291839700941773,-0.546410842239735,-0.412958796825298,0.6361522503407359,0.020446217421404334,-0.36882191692968064,0.27179356591045745,1.099790142352336,-0.06480379588709152,-0.546410842239735,-0.3248598804887178,0.6361522503407359,1.4329258820598159,-0.15077592925131486,0.06279828060143189,0.31303318522898527,-0.7267490661171271,-0.4572697498231123
3,367
Ribosomal large subunit assembly
13
23
2.707901
0.006771
Q9BYC9,P46777,Q02878,Q9NU22,P27635,P46087,P63173,Q9H7B2,Q9NQ55,P62750,Q8TDN6,P39023,P83731
Processes and pathways
GO Biological process
msigdb_gobp
204,292,366,241,195,545,140,451,621,363,422,118,155
2584,195,118,545,292,363,2264,140,155,366,860,1336,1131,422,204,451,621,241,2131,1645,657,1968,2715
-0.546410842239735,1.2863020037686608,1.613148049789865,0.6361522503407359,1.0241336866990407,0.8709321917690549,-0.36882191692968064,1.5054130123499248,1.4329258820598159,0.8709321917690549,0.3949453920319386,0.10496721166567786,0.23036622014532987,0.7933537558921767,1.2863020037686608,0.754312439228042,0.5964120554641071,1.1748381597601374,-0.2810734678085235,-0.022088097488964575,0.5564909583357176,-0.1940306860173823,-0.5912394888767456
3,367
Actin filament based movement
10
31
2.705365
0.006823
Q9UM22,Q12965,Q13459,O94832,O43795,Q99996,Q9Y4I1,P35580,P60660,P35579
Processes and pathways
GO Biological process
msigdb_gobp
8,261,262,319,206,79,287,387,217,245
1450,407,1369,1302,206,2244,319,2796,2798,2588,1173,1109,1578,245,387,217,261,262,1402,744,745,2191,874,1270,1636,79,703,3086,8,890,287
0.020446217421404334,0.7933537558921767,0.06279828060143189,0.10496721166567786,1.249292736644776,-0.36882191692968064,0.9478531474732188,-0.6814093200124656,-0.6814093200124656,-0.546410842239735,0.18875209347989597,0.23036622014532987,-0.022088097488964575,1.1373892537486945,0.8322262551325478,1.212138715175788,1.099790142352336,1.099790142352336,0.06279828060143189,0.4760956266149155,0.4760956266149155,-0.3248598804887178,0.3949453920319386,0.14695211780225223,-0.022088097488964575,2.0670777141599412,0.51638636702171,-0.9559681035265681,5.347423495313898,0.3949453920319386,1.0620389315076852
3,367
Immunoglobulin-like fold [IPR013783]
10
36
2.694632
0.007047
P10321,Q8IZA0,O00462,P04439,P55899,Q9BX67,P01889,P35613,Q14118,P43121
Sequence
InterPro Superfamily
interpro_homologous_superfamily
213,39,40,73,43,313,84,305,327,342
40,720,1822,1558,1167,630,358,2725,84,73,213,1109,305,342,1928,43,1183,2962,2091,3245,1855,327,1125,1499,2685,1948,2030,39,2544,1625,1633,313,2412,3209,2641,775
3.1081955602316613,0.4760956266149155,-0.15077592925131486,-0.022088097488964575,0.18875209347989597,0.5564909583357176,0.8709321917690549,-0.6362392226649662,1.9985415804284918,2.1011771507196184,1.212138715175788,0.23036622014532987,0.9860724317343753,0.909473770504105,-0.1940306860173823,3.0458947300580568,0.18875209347989597,-0.8179346882917339,-0.2810734678085235,-1.3312935370263337,-0.15077592925131486,0.9478531474732188,0.23036622014532987,0.020446217421404334,-0.5912394888767456,-0.1940306860173823,-0.23746346936348223,3.13922056117222,-0.5017540153159744,-0.022088097488964575,-0.022088097488964575,0.9860724317343753,-0.412958796825298,-1.1893259001279373,-0.546410842239735,0.4760956266149155
3,367
Abnormal systemic arterial morphology
32
155
2.694237
0.007055
Q9UBM7,Q9H7D7,Q07020,P05067,P07602,P61916,P61353,Q9NZJ7,Q9Y4A5,P46777,P16278,P18077,P17900,P06865,P42766,O75531,P10253,P10619,Q14839,P62899,P61313,P62847,Q6ZXV5,O15118,P01889,Q8WYQ5,Q9NZC9,Q86V48,P19022,P42858,P07686,Q13510
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
1,268,134,14,17,25,275,162,174,292,164,165,46,47,177,301,59,68,199,198,74,197,347,81,84,87,97,98,214,100,103,104
2235,81,2331,3146,498,2719,1226,1104,1029,2788,960,2789,1167,301,725,3173,1904,727,2066,3255,84,3148,841,14,730,47,17,103,1230,59,68,1748,2990,2073,164,46,1042,165,732,214,671,1109,2349,1752,1993,1754,1670,2733,2164,2353,1579,1580,2259,2000,1389,2168,3095,2513,177,100,2996,292,3227,1049,2084,546,1588,849,2007,1589,2916,1930,1590,851,910,74,275,25,2599,1054,2742,680,855,197,1681,198,2264,2089,978,742,682,2815,2182,134,797,2376,104,1856,1060,2021,199,3302,1188,3196,2924,2753,2606,1864,1865,347,1342,1343,610,98,611,811,2468,2471,87,2548,1205,1273,924,1350,349,927,996,3201,1636,1637,2207,1281,821,2629,268,3082,2563,765,1966,97,162,1,1013,2637,2980,710,889,624,1652,3192,2232,174,952,774,2418
-0.36882191692968064,2.032866242545018,-0.412958796825298,-1.0954913801193207,0.6757140740040977,-0.6362392226649662,0.14695211780225223,0.23036622014532987,0.27179356591045745,-0.6814093200124656,0.31303318522898527,-0.6814093200124656,0.18875209347989597,0.9860724317343753,0.4760956266149155,-1.142327166182432,-0.1940306860173823,0.4760956266149155,-0.2810734678085235,-1.378937844623164,1.9985415804284918,-1.0954913801193207,0.3949453920319386,4.815860976496678,0.4760956266149155,2.9518057266228475,4.3750256940936305,1.719723884747831,0.14695211780225223,2.4362503004565204,2.1690444425785262,-0.10770002139860704,-0.8637791771530676,-0.2810734678085235,1.3964785412072227,3.014617485988229,0.27179356591045745,1.3964785412072227,0.4760956266149155,1.212138715175788,0.51638636702171,0.23036622014532987,-0.412958796825298,-0.10770002139860704,-0.23746346936348223,-0.10770002139860704,-0.06480379588709152,-0.6362392226649662,-0.3248598804887178,-0.412958796825298,-0.022088097488964575,-0.022088097488964575,-0.36882191692968064,-0.23746346936348223,0.06279828060143189,-0.3248598804887178,-1.0023112020703986,-0.5017540153159744,1.3598932144259221,1.7549981936289338,-0.8637791771530676,1.0241336866990407,-1.2838097038521317,0.27179356591045745,-0.2810734678085235,0.6361522503407359,-0.022088097488964575,0.3949453920319386,-0.23746346936348223,-0.022088097488964575,-0.7722577547913748,-0.1940306860173823,-0.022088097488964575,0.3949453920319386,0.3540841185619894,2.0670777141599412,1.0620389315076852,3.772633277255873,-0.546410842239735,0.27179356591045745,-0.6362392226649662,0.51638636702171,0.3949453920319386,1.2863020037686608,-0.06480379588709152,1.2863020037686608,-0.36882191692968064,-0.2810734678085235,0.31303318522898527,0.4760956266149155,0.51638636702171,-0.6814093200124656,-0.3248598804887178,1.5414559276361184,0.4356160170646649,-0.412958796825298,1.719723884747831,-0.15077592925131486,0.27179356591045745,-0.23746346936348223,1.2863020037686608,-1.6195456688999854,0.18875209347989597,-1.1893259001279373,-0.7722577547913748,-0.6362392226649662,-0.546410842239735,-0.15077592925131486,-0.15077592925131486,0.909473770504105,0.10496721166567786,0.10496721166567786,0.5964120554641071,1.790149299150869,0.5964120554641071,0.4356160170646649,-0.4572697498231123,-0.4572697498231123,1.9641025522127773,-0.5017540153159744,0.18875209347989597,0.14695211780225223,0.3540841185619894,0.10496721166567786,0.909473770504105,0.3540841185619894,0.31303318522898527,-1.1893259001279373,-0.022088097488964575,-0.022088097488964575,-0.3248598804887178,0.14695211780225223,0.4356160170646649,-0.546410842239735,1.099790142352336,-0.9559681035265681,-0.5017540153159744,0.4760956266149155,-0.1940306860173823,1.8251785328251016,1.4329258820598159,6.354521266861696,0.31303318522898527,-0.546410842239735,-0.8179346882917339,0.51638636702171,0.3949453920319386,0.5964120554641071,-0.022088097488964575,-1.142327166182432,-0.3248598804887178,1.3964785412072227,0.3540841185619894,0.4760956266149155,-0.412958796825298
3,367
Abnormality of the autonomic nervous system
8
65
2.687185
0.007206
Q9UBM7,P35251,P07686,Q99996,P42892,P07602,P06280,Q9NZJ7
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
1,153,103,79,16,17,23,162
497,1025,1659,2331,1301,895,1029,300,2792,2337,841,23,17,103,413,3240,1752,153,2082,2000,3128,2355,16,906,3178,1325,2007,2091,515,2182,1772,1334,1406,2674,1780,2106,2756,1864,919,200,811,876,2548,1205,1273,698,1277,996,1074,816,1075,2480,79,821,2629,2211,2774,1722,765,162,1,889,950,2717,837
0.6757140740040977,0.27179356591045745,-0.06480379588709152,-0.412958796825298,0.10496721166567786,0.3540841185619894,0.27179356591045745,0.9860724317343753,-0.6814093200124656,-0.412958796825298,0.3949453920319386,3.860476447122193,4.3750256940936305,1.719723884747831,0.7933537558921767,-1.3312935370263337,-0.10770002139860704,1.4329258820598159,-0.2810734678085235,-0.23746346936348223,-1.0488191777371687,-0.412958796825298,4.4588127644301565,0.3540841185619894,-1.142327166182432,0.10496721166567786,-0.23746346936348223,-0.2810734678085235,0.6757140740040977,-0.3248598804887178,-0.10770002139860704,0.10496721166567786,0.06279828060143189,-0.5912394888767456,-0.10770002139860704,-0.2810734678085235,-0.6362392226649662,-0.15077592925131486,0.3540841185619894,1.2863020037686608,0.4356160170646649,0.3949453920319386,-0.5017540153159744,0.18875209347989597,0.14695211780225223,0.51638636702171,0.14695211780225223,0.31303318522898527,0.27179356591045745,0.4356160170646649,0.27179356591045745,-0.4572697498231123,2.0670777141599412,0.4356160170646649,-0.546410842239735,-0.3248598804887178,-0.6362392226649662,-0.06480379588709152,0.4760956266149155,1.4329258820598159,6.354521266861696,0.3949453920319386,0.3540841185619894,-0.5912394888767456,0.4356160170646649
3,367
Carbohydrate catabolic process
6
50
2.683855
0.007278
P07686,O00462,Q14108,P17900,P05067,P10253
Processes and pathways
GO Biological process
msigdb_gobp
103,40,27,46,14,59
40,1976,1984,1985,2795,1463,1568,2582,14,2585,1169,2157,103,1569,502,2505,59,1571,1829,164,1041,46,3280,2907,440,508,2738,636,2515,1052,1482,2261,2172,1679,1845,1240,1593,2742,1598,1934,2668,2812,645,27,649,818,1435,2130,947,770
3.1081955602316613,-0.23746346936348223,-0.23746346936348223,-0.23746346936348223,-0.6814093200124656,0.020446217421404334,-0.022088097488964575,-0.546410842239735,4.815860976496678,-0.546410842239735,0.18875209347989597,-0.3248598804887178,1.719723884747831,-0.022088097488964575,0.6757140740040977,-0.5017540153159744,2.4362503004565204,-0.022088097488964575,-0.15077592925131486,1.3964785412072227,0.27179356591045745,3.014617485988229,-1.4747054833332776,-0.7722577547913748,0.754312439228042,0.6757140740040977,-0.6362392226649662,0.5564909583357176,-0.5017540153159744,0.27179356591045745,0.020446217421404334,-0.36882191692968064,-0.3248598804887178,-0.06480379588709152,-0.15077592925131486,0.14695211780225223,-0.022088097488964575,-0.6362392226649662,-0.022088097488964575,-0.1940306860173823,-0.5912394888767456,-0.6814093200124656,0.5564909583357176,3.6248188309031892,0.5564909583357176,0.4356160170646649,0.06279828060143189,-0.2810734678085235,0.3540841185619894,0.4760956266149155
3,367
Cytoskeletal motor activity
11
31
2.680662
0.007348
Q14204,Q13459,Q12965,O94832,O43795,Q9Y4I1,Q8NCM8,Q2M1P5,P35580,P60660,P35579
Functions
GO Molecular function
msigdb_gomf
328,262,261,319,206,287,181,371,387,217,245
953,407,206,1029,319,1306,1033,2166,245,387,2005,217,1184,2669,2524,261,2092,262,328,1690,371,2191,181,1208,1077,1804,1892,890,1727,834,287
0.31303318522898527,0.7933537558921767,1.249292736644776,0.27179356591045745,0.9478531474732188,0.10496721166567786,0.27179356591045745,-0.3248598804887178,1.1373892537486945,0.8322262551325478,-0.23746346936348223,1.212138715175788,0.18875209347989597,-0.5912394888767456,-0.5017540153159744,1.099790142352336,-0.2810734678085235,1.099790142352336,0.9478531474732188,-0.06480379588709152,0.8709321917690549,-0.3248598804887178,1.3598932144259221,0.18875209347989597,0.27179356591045745,-0.10770002139860704,-0.15077592925131486,0.3949453920319386,-0.06480379588709152,0.4356160170646649,1.0620389315076852
3,367
Abnormal rib cage morphology
14
76
2.675278
0.007467
O43933,Q9UBM7,Q86V48,Q99575,P04066,Q14739,P16278,O00754,P15586,Q8NCM8,Q12768,P51798,Q92917,P54802
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
96,1,98,266,6,38,164,44,13,181,121,307,281,54
44,497,3211,2576,96,1902,1167,1980,301,3238,1904,727,1743,2068,1377,3148,6,1037,13,164,2991,732,2348,1109,1993,2949,3241,1670,3095,3128,793,2360,1585,307,54,1846,3229,1183,742,682,3130,2815,2744,121,1119,2376,38,1780,2024,2750,521,2533,2753,691,1864,1865,1949,98,181,2471,1624,281,2476,1523,927,2207,266,1142,1889,2308,1,3022,2980,2982,2642,2418
3.014617485988229,0.6757140740040977,-1.2364869532593843,-0.546410842239735,1.8251785328251016,-0.1940306860173823,0.18875209347989597,-0.23746346936348223,0.9860724317343753,-1.3312935370263337,-0.1940306860173823,0.4760956266149155,-0.10770002139860704,-0.2810734678085235,0.06279828060143189,-1.0954913801193207,5.477203395245907,0.27179356591045745,4.896921049154351,1.3964785412072227,-0.8637791771530676,0.4760956266149155,-0.412958796825298,0.23036622014532987,-0.23746346936348223,-0.8179346882917339,-1.3312935370263337,-0.06480379588709152,-1.0023112020703986,-1.0488191777371687,0.4356160170646649,-0.412958796825298,-0.022088097488964575,0.9860724317343753,2.664757267155283,-0.15077592925131486,-1.2838097038521317,0.18875209347989597,0.4760956266149155,0.51638636702171,-1.0488191777371687,-0.6814093200124656,-0.6362392226649662,1.613148049789865,0.23036622014532987,-0.412958796825298,3.1701628794451158,-0.10770002139860704,-0.23746346936348223,-0.6362392226649662,0.6757140740040977,-0.5017540153159744,-0.6362392226649662,0.51638636702171,-0.15077592925131486,-0.15077592925131486,-0.1940306860173823,1.790149299150869,1.3598932144259221,-0.4572697498231123,-0.022088097488964575,1.0620389315076852,-0.4572697498231123,0.020446217421404334,0.3540841185619894,-0.3248598804887178,1.099790142352336,0.23036622014532987,-0.15077592925131486,-0.36882191692968064,6.354521266861696,-0.8637791771530676,-0.8179346882917339,-0.8179346882917339,-0.546410842239735,-0.412958796825298
3,367
Early endosome
23
98
2.672158
0.007537
P05067,Q9Y4I1,O60879,Q92542,Q9UIQ6,Q8IV08,P11717,P27695,O75165,Q15043,P02786,Q9BUN8,Q7Z3U7,P04439,O43795,P01889,P10321,P42858,Q13510,Q12768,Q9Y2I1,Q07954,O14786
Localization
GO Cellular component
msigdb_gocc
14,287,138,159,32,51,53,304,300,330,67,335,201,73,206,84,213,100,104,121,126,120,127
2572,127,1098,1103,2146,206,2424,2242,138,300,1981,501,319,437,84,67,2155,73,14,213,3124,53,2433,2732,2436,3126,304,1670,2659,507,1477,3242,3066,2355,2955,100,1927,1243,737,2011,2522,1183,742,120,121,2526,104,3157,1122,2672,2922,330,803,3102,689,1263,2027,479,988,693,201,1346,51,2290,1073,159,563,2476,1353,3349,1074,1713,2768,3221,335,1804,936,3141,2403,3165,2226,945,532,1088,32,3024,2840,2893,832,2054,2322,3170,2137,1650,833,126,287,3172
-0.546410842239735,1.5773671103553362,0.23036622014532987,0.23036622014532987,-0.3248598804887178,1.249292736644776,-0.4572697498231123,-0.36882191692968064,1.5054130123499248,0.9860724317343753,-0.23746346936348223,0.6757140740040977,0.9478531474732188,0.754312439228042,1.9985415804284918,2.202814512277326,-0.3248598804887178,2.1011771507196184,4.815860976496678,1.212138715175788,-1.0488191777371687,2.664757267155283,-0.4572697498231123,-0.6362392226649662,-0.4572697498231123,-1.0488191777371687,0.9860724317343753,-0.06480379588709152,-0.5912394888767456,0.6757140740040977,0.020446217421404334,-1.3312935370263337,-0.9559681035265681,-0.412958796825298,-0.8179346882917339,1.7549981936289338,-0.1940306860173823,0.14695211780225223,0.4760956266149155,-0.23746346936348223,-0.5017540153159744,0.18875209347989597,0.4760956266149155,1.613148049789865,1.613148049789865,-0.5017540153159744,1.719723884747831,-1.0954913801193207,0.23036622014532987,-0.5912394888767456,-0.7722577547913748,0.9478531474732188,0.4356160170646649,-1.0023112020703986,0.51638636702171,0.14695211780225223,-0.23746346936348223,0.7150999985878068,0.31303318522898527,0.51638636702171,1.2863020037686608,0.10496721166567786,2.7291839700941773,-0.36882191692968064,0.27179356591045745,1.4329258820598159,0.6361522503407359,-0.4572697498231123,0.10496721166567786,-2.5177406421925412,0.27179356591045745,-0.06480379588709152,-0.6362392226649662,-1.2364869532593843,0.9478531474732188,-0.10770002139860704,0.3540841185619894,-1.0488191777371687,-0.412958796825298,-1.0954913801193207,-0.3248598804887178,0.3540841185619894,0.6757140740040977,0.27179356591045745,3.354118052447859,-0.8637791771530676,-0.6814093200124656,-0.7267490661171271,0.4356160170646649,-0.23746346936348223,-0.36882191692968064,-1.0954913801193207,-0.2810734678085235,-0.022088097488964575,0.4356160170646649,1.613148049789865,1.0620389315076852,-1.0954913801193207
3,367
Fcgamma receptor fcgr dependent phagocytosis
10
32
2.665662
0.007684
Q7L576,O15143,Q14185,Q13459,Q12965,Q96F07,Q9Y4I1,Q8IV08,Q9UQB8,P35579
Processes and pathways
Reactome Pathways
msigdb_reactome
263,338,101,262,261,111,287,51,29,245
407,1369,338,2786,2143,2158,2071,1472,1669,3126,1670,245,2263,1117,3097,2370,2012,1245,2268,261,262,101,1189,263,51,2037,111,1278,2225,29,661,287
0.7933537558921767,0.06279828060143189,0.909473770504105,-0.6814093200124656,-0.3248598804887178,-0.3248598804887178,-0.2810734678085235,0.020446217421404334,-0.06480379588709152,-1.0488191777371687,-0.06480379588709152,1.1373892537486945,-0.36882191692968064,0.23036622014532987,-1.0023112020703986,-0.412958796825298,-0.23746346936348223,0.14695211780225223,-0.36882191692968064,1.099790142352336,1.099790142352336,1.7549981936289338,0.18875209347989597,1.099790142352336,2.7291839700941773,-0.23746346936348223,1.6843250163853651,0.14695211780225223,-0.3248598804887178,3.535260987655072,0.5564909583357176,1.0620389315076852
3,367
Late endosome
17
65
2.657695
0.007868
Q658P3,Q9Y2Q5,Q9BUN8,P11279,P42858,Q13501,Q9Y4I1,P07602,O15118,Q8IV08,Q99538,P11717,Q99570,P13473,Q14108,Q9NZJ7,Q15043
Localization
GO Cellular component
msigdb_gocc
36,136,335,90,100,234,287,17,81,51,20,53,350,26,27,162,330
2572,1098,81,1103,3062,1899,3235,2986,17,3312,1748,2587,90,53,26,967,592,3126,1670,3066,100,908,1243,742,234,27,370,330,479,36,690,51,752,1953,2290,617,2760,2476,1878,1425,1636,1074,758,20,350,2768,700,335,1286,1884,3141,2403,3165,763,2219,162,2226,3022,1088,623,3170,833,136,3354,287
-0.546410842239735,0.23036622014532987,2.032866242545018,0.23036622014532987,-0.9559681035265681,-0.1940306860173823,-1.3312935370263337,-0.8637791771530676,4.3750256940936305,-1.7657985305992057,-0.10770002139860704,-0.546410842239735,1.8948765913387664,2.664757267155283,3.713721512871941,0.31303318522898527,0.5964120554641071,-1.0488191777371687,-0.06480379588709152,-0.9559681035265681,1.7549981936289338,0.3540841185619894,0.14695211780225223,0.4760956266149155,1.1748381597601374,3.6248188309031892,0.8709321917690549,0.9478531474732188,0.7150999985878068,3.201023198065498,0.51638636702171,2.7291839700941773,0.4760956266149155,-0.1940306860173823,-0.36882191692968064,0.5964120554641071,-0.6362392226649662,-0.4572697498231123,-0.15077592925131486,0.06279828060143189,-0.022088097488964575,0.27179356591045745,0.4760956266149155,3.9186948792031995,0.909473770504105,-0.6362392226649662,0.51638636702171,0.9478531474732188,0.14695211780225223,-0.15077592925131486,-1.0488191777371687,-0.412958796825298,-1.0954913801193207,0.4760956266149155,-0.3248598804887178,1.4329258820598159,-0.3248598804887178,-0.8637791771530676,0.27179356591045745,0.5964120554641071,-1.0954913801193207,0.4356160170646649,1.5414559276361184,-2.6721680762670923,1.0620389315076852
3,367
Developmental maturation
6
44
2.647575
0.008107
O75503,Q15125,Q8N2A8,P05067,Q12768,Q9NZJ7
Processes and pathways
GO Biological process
msigdb_gobp
3,7,142,14,121,162
183,2575,959,2064,629,3,1744,841,2430,14,3065,731,2248,1572,1990,1042,2164,1914,1049,2083,1325,1682,3245,1250,121,858,2526,2093,327,7,3102,1188,1067,916,557,142,614,399,998,1961,162,889,2943,2233
1.3231682601538646,-0.546410842239735,0.31303318522898527,-0.2810734678085235,0.5564909583357176,5.682423722639393,-0.10770002139860704,0.3949453920319386,-0.4572697498231123,4.815860976496678,-0.9559681035265681,0.4760956266149155,-0.36882191692968064,-0.022088097488964575,-0.23746346936348223,0.27179356591045745,-0.3248598804887178,-0.1940306860173823,0.27179356591045745,-0.2810734678085235,0.10496721166567786,-0.06480379588709152,-1.3312935370263337,0.14695211780225223,1.613148049789865,0.3949453920319386,-0.5017540153159744,-0.2810734678085235,0.9478531474732188,5.347423495313898,-1.0023112020703986,0.18875209347989597,0.27179356591045745,0.3540841185619894,0.6361522503407359,1.5054130123499248,0.5964120554641071,0.8322262551325478,0.31303318522898527,-0.1940306860173823,1.4329258820598159,0.3949453920319386,-0.7722577547913748,-0.3248598804887178
3,367
Lipid localization
13
76
2.637806
0.008344
Q07954,P29375,Q99720,P07686,Q8WTV0,P17900,P07602,O15260,O15118,Q9BUR5,P61916,Q14108,P14174
Processes and pathways
GO Biological process
msigdb_gobp
120,69,37,103,110,46,17,49,81,85,25,27,116
1898,1163,1298,81,49,1561,1373,1303,3235,633,1663,411,2794,2655,841,2155,2986,17,103,1310,3340,466,116,46,1110,2993,2437,258,69,290,1477,2995,361,635,2002,1393,25,603,1686,2268,2815,120,645,27,1857,370,3196,690,1696,1346,3219,3330,110,2763,2765,758,37,2887,2626,85,1884,1533,2560,571,1358,826,2219,162,2412,708,831,1014,2320,3170,3059,1224
-0.1940306860173823,0.18875209347989597,0.10496721166567786,2.032866242545018,2.793240616952005,-0.022088097488964575,0.06279828060143189,0.10496721166567786,-1.3312935370263337,0.5564909583357176,-0.06480379588709152,0.7933537558921767,-0.6814093200124656,-0.5912394888767456,0.3949453920319386,-0.3248598804887178,-0.8637791771530676,4.3750256940936305,1.719723884747831,0.10496721166567786,-2.3646418191340213,0.7150999985878068,1.613148049789865,3.014617485988229,0.23036622014532987,-0.8637791771530676,-0.4572697498231123,1.099790142352336,2.1690444425785262,1.0241336866990407,0.020446217421404334,-0.8637791771530676,0.8709321917690549,0.5564909583357176,-0.23746346936348223,0.06279828060143189,3.772633277255873,0.5964120554641071,-0.06480379588709152,-0.36882191692968064,-0.6814093200124656,1.613148049789865,0.5564909583357176,3.6248188309031892,-0.15077592925131486,0.8709321917690549,-1.1893259001279373,0.51638636702171,-0.06480379588709152,0.10496721166567786,-1.2364869532593843,-2.0624824111997717,1.6843250163853651,-0.6362392226649662,-0.6362392226649662,0.4760956266149155,3.201023198065498,-0.7267490661171271,-0.546410842239735,1.9985415804284918,-0.15077592925131486,0.020446217421404334,-0.5017540153159744,0.6361522503407359,0.10496721166567786,0.4356160170646649,-0.3248598804887178,1.4329258820598159,-0.412958796825298,0.51638636702171,0.4356160170646649,0.31303318522898527,-0.36882191692968064,-1.0954913801193207,-0.9097905400273109,0.18875209347989597
3,367
Abnormal vertebral morphology
20
110
2.634404
0.008429
Q9UBM7,Q99575,P04066,Q15125,P15586,Q14108,Q14739,P16278,O00754,Q9NUQ7,Q8NCM8,P51798,P54802,P10619,Q8IWS0,Q96HA7,Q9NZC9,O00170,Q12768,Q8IY37
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
1,266,6,7,13,27,38,164,44,315,181,307,54,68,332,349,97,337,121,251
3089,337,1225,44,497,840,3211,2576,1104,895,2064,960,1902,1167,3238,3278,1743,2068,1377,841,6,1037,68,1748,2904,13,164,2991,732,2348,1109,3241,1043,2165,1580,2082,1581,3314,3095,906,3257,2360,307,3352,54,2520,1846,2599,1683,2089,3180,3000,1183,682,1772,121,1774,1119,2376,27,38,1690,3302,7,1780,1497,2024,371,521,2533,2534,2753,2606,2822,2281,1949,1343,332,251,811,181,2471,1624,2038,349,1523,1353,927,996,266,2629,1889,2308,2484,3085,315,765,97,1,3022,2637,2980,710,889,2982,662,3117,2642,774,2418
-1.0023112020703986,0.909473770504105,0.14695211780225223,3.014617485988229,0.6757140740040977,0.3949453920319386,-1.2364869532593843,-0.546410842239735,0.23036622014532987,0.3540841185619894,-0.2810734678085235,0.31303318522898527,-0.1940306860173823,0.18875209347989597,-1.3312935370263337,-1.4747054833332776,-0.10770002139860704,-0.2810734678085235,0.06279828060143189,0.3949453920319386,5.477203395245907,0.27179356591045745,2.1690444425785262,-0.10770002139860704,-0.7722577547913748,4.896921049154351,1.3964785412072227,-0.8637791771530676,0.4760956266149155,-0.412958796825298,0.23036622014532987,-1.3312935370263337,0.27179356591045745,-0.3248598804887178,-0.022088097488964575,-0.2810734678085235,-0.022088097488964575,-1.7657985305992057,-1.0023112020703986,0.3540841185619894,-1.378937844623164,-0.412958796825298,0.9860724317343753,-2.6721680762670923,2.664757267155283,-0.5017540153159744,-0.15077592925131486,-0.546410842239735,-0.06480379588709152,-0.2810734678085235,-1.142327166182432,-0.8637791771530676,0.18875209347989597,0.51638636702171,-0.10770002139860704,1.613148049789865,-0.10770002139860704,0.23036622014532987,-0.412958796825298,3.6248188309031892,3.1701628794451158,-0.06480379588709152,-1.6195456688999854,5.347423495313898,-0.10770002139860704,0.020446217421404334,-0.23746346936348223,0.8709321917690549,0.6757140740040977,-0.5017540153159744,-0.5017540153159744,-0.6362392226649662,-0.546410842239735,-0.6814093200124656,-0.36882191692968064,-0.1940306860173823,0.10496721166567786,0.9478531474732188,1.1373892537486945,0.4356160170646649,1.3598932144259221,-0.4572697498231123,-0.022088097488964575,-0.23746346936348223,0.909473770504105,0.020446217421404334,0.10496721166567786,0.3540841185619894,0.31303318522898527,1.099790142352336,-0.546410842239735,-0.15077592925131486,-0.36882191692968064,-0.4572697498231123,-0.9559681035265681,0.9860724317343753,0.4760956266149155,1.8251785328251016,6.354521266861696,-0.8637791771530676,-0.546410842239735,-0.8179346882917339,0.51638636702171,0.3949453920319386,-0.8179346882917339,0.5564909583357176,-1.0023112020703986,-0.546410842239735,0.4760956266149155,-0.412958796825298
3,367
Terpenoid metabolic process
6
15
2.631842
0.008492
P29375,Q8TC12,Q9HB40,Q6NUM9,Q07954,P37268
Processes and pathways
GO Biological process
msigdb_gobp
69,172,9,76,120,30
2147,1909,2731,1990,69,30,215,2596,3339,120,76,878,172,9,1093
-0.3248598804887178,-0.1940306860173823,-0.6362392226649662,-0.23746346936348223,2.1690444425785262,3.4751842548839553,1.212138715175788,-0.546410842239735,-2.3139063625418146,1.613148049789865,2.0670777141599412,0.3949453920319386,1.3964785412072227,5.321323717121585,0.27179356591045745
3,367
Intrinsic component of organelle membrane
16
111
2.631052
0.008512
Q9UBM7,P10321,Q9NZ01,Q14739,Q15125,Q5J8M3,P04439,P42892,O15118,L0R6Q1,P01889,Q9BUR5,Q9H490,P13473,Q9HC21,O96008
Localization
GO Cellular component
msigdb_gocc
1,213,336,38,7,170,73,16,81,83,84,85,284,26,192,271
1898,83,954,583,1298,81,1371,1558,537,2146,1373,1901,1165,1980,1904,2151,2792,3033,2653,963,668,462,271,84,73,213,1040,26,2435,2436,2800,846,2735,3314,16,1393,908,2086,973,1053,679,739,912,1935,1403,2378,38,861,519,686,7,2189,1606,1407,2277,2460,170,2462,868,1786,1506,870,750,3011,1346,1951,2111,1701,1620,2542,1872,561,1954,485,1955,1517,2930,2041,1528,3290,2769,2626,2209,335,85,1003,1287,284,2212,3052,192,764,384,3166,574,2780,1647,336,767,1011,1,622,1544,3086,1445,2323,3192,774,2493,836,1224
-0.1940306860173823,1.9985415804284918,0.31303318522898527,0.5964120554641071,0.10496721166567786,2.032866242545018,0.06279828060143189,-0.022088097488964575,0.6361522503407359,-0.3248598804887178,0.06279828060143189,-0.1940306860173823,0.18875209347989597,-0.23746346936348223,-0.1940306860173823,-0.3248598804887178,-0.6814093200124656,-0.9097905400273109,-0.5912394888767456,0.31303318522898527,0.51638636702171,0.7150999985878068,1.0620389315076852,1.9985415804284918,2.1011771507196184,1.212138715175788,0.27179356591045745,3.713721512871941,-0.4572697498231123,-0.4572697498231123,-0.6814093200124656,0.3949453920319386,-0.6362392226649662,-1.7657985305992057,4.4588127644301565,0.06279828060143189,0.3540841185619894,-0.2810734678085235,0.31303318522898527,0.27179356591045745,0.51638636702171,0.4760956266149155,0.3540841185619894,-0.1940306860173823,0.06279828060143189,-0.412958796825298,3.1701628794451158,0.3949453920319386,0.6757140740040977,0.51638636702171,5.347423495313898,-0.3248598804887178,-0.022088097488964575,0.06279828060143189,-0.36882191692968064,-0.4572697498231123,1.3964785412072227,-0.4572697498231123,0.3949453920319386,-0.10770002139860704,0.020446217421404334,0.3949453920319386,0.4760956266149155,-0.8637791771530676,0.10496721166567786,-0.1940306860173823,-0.2810734678085235,-0.06480379588709152,-0.022088097488964575,-0.5017540153159744,-0.15077592925131486,0.6361522503407359,-0.1940306860173823,0.7150999985878068,-0.1940306860173823,0.020446217421404334,-0.7722577547913748,-0.23746346936348223,0.020446217421404334,-1.52282763066264,-0.6362392226649662,-0.546410842239735,-0.3248598804887178,0.9478531474732188,1.9985415804284918,0.31303318522898527,0.14695211780225223,1.0620389315076852,-0.3248598804887178,-0.9097905400273109,1.3231682601538646,0.4760956266149155,0.8709321917690549,-1.0954913801193207,0.6361522503407359,-0.6362392226649662,-0.022088097488964575,0.9478531474732188,0.4760956266149155,0.31303318522898527,6.354521266861696,0.5964120554641071,0.020446217421404334,-0.9559681035265681,0.06279828060143189,-0.36882191692968064,-1.142327166182432,0.4760956266149155,-0.4572697498231123,0.4356160170646649,0.18875209347989597
3,367
Increased head circumference
39
133
2.63074
0.00852
Q15392,Q07864,Q99575,O14802,O14646,Q9HCK8,P07602,P53007,Q9NZJ7,P41229,Q14739,O00754,Q8NCM8,Q93008,O43505,P51798,Q14118,Q8IWS0,Q14839,Q7Z6Z7,Q8IYB7,Q8WVX9,Q9BU61,Q9NR50,Q96HA7,P11310,P11166,O43933,P19022,O75970,P42858,O75962,P07686,P42345,P49770,P10412,Q12768,Q2M1P5,Q96HP0
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
0,367,266,497,132,402,17,510,162,33,38,44,181,311,537,307,327,332,199,610,611,485,351,492,349,91,466,96,214,340,100,358,103,107,470,112,121,371,253
2235,44,132,497,1555,1099,3211,537,96,2064,1823,1902,2789,629,1305,2985,1031,725,1904,358,340,1462,3255,3148,17,103,2727,2340,112,466,91,2905,732,214,2349,1754,3225,3066,2954,33,107,100,793,2003,470,2360,1585,1325,1928,2363,307,3352,510,2916,1930,972,973,2742,1245,1765,978,742,2920,2182,367,1772,121,2963,797,2868,913,2376,1334,799,1251,327,605,1060,1406,2457,38,199,2529,1692,0,1497,1860,1407,1189,371,1194,2753,1342,610,332,611,811,2468,181,2296,485,1956,2202,311,1877,1517,349,253,1353,996,1637,2208,266,1281,351,2629,822,1534,2211,2776,3052,402,492,1437,2410,162,3022,3167,1725,889,1015,1652,2646
-0.36882191692968064,3.014617485988229,1.5414559276361184,0.6757140740040977,-0.022088097488964575,0.23036622014532987,-1.2364869532593843,0.6361522503407359,1.8251785328251016,-0.2810734678085235,-0.15077592925131486,-0.1940306860173823,-0.6814093200124656,0.5564909583357176,0.10496721166567786,-0.8637791771530676,0.27179356591045745,0.4760956266149155,-0.1940306860173823,0.8709321917690549,0.909473770504105,0.020446217421404334,-1.378937844623164,-1.0954913801193207,4.3750256940936305,1.719723884747831,-0.6362392226649662,-0.412958796825298,1.6488002071649115,0.7150999985878068,1.8948765913387664,-0.7722577547913748,0.4760956266149155,1.212138715175788,-0.412958796825298,-0.10770002139860704,-1.2838097038521317,-0.9559681035265681,-0.8179346882917339,3.3236578103542245,1.6843250163853651,1.7549981936289338,0.4356160170646649,-0.23746346936348223,0.7150999985878068,-0.412958796825298,-0.022088097488964575,0.10496721166567786,-0.1940306860173823,-0.412958796825298,0.9860724317343753,-2.6721680762670923,0.6757140740040977,-0.7722577547913748,-0.1940306860173823,0.31303318522898527,0.31303318522898527,-0.6362392226649662,0.14695211780225223,-0.10770002139860704,0.31303318522898527,0.4760956266149155,-0.7722577547913748,-0.3248598804887178,0.8709321917690549,-0.10770002139860704,1.613148049789865,-0.8179346882917339,0.4356160170646649,-0.7267490661171271,0.3540841185619894,-0.412958796825298,0.10496721166567786,0.4356160170646649,0.14695211780225223,0.9478531474732188,0.5964120554641071,0.27179356591045745,0.06279828060143189,-0.4572697498231123,3.1701628794451158,1.2863020037686608,-0.5017540153159744,-0.06480379588709152,9.266342596549883,0.020446217421404334,-0.15077592925131486,0.06279828060143189,0.18875209347989597,0.8709321917690549,0.18875209347989597,-0.6362392226649662,0.10496721166567786,0.5964120554641071,0.9478531474732188,0.5964120554641071,0.4356160170646649,-0.4572697498231123,1.3598932144259221,-0.36882191692968064,0.7150999985878068,-0.1940306860173823,-0.3248598804887178,0.9860724317343753,-0.15077592925131486,0.020446217421404334,0.909473770504105,1.1373892537486945,0.10496721166567786,0.31303318522898527,-0.022088097488964575,-0.3248598804887178,1.099790142352336,0.14695211780225223,0.909473770504105,-0.546410842239735,0.4356160170646649,0.020446217421404334,-0.3248598804887178,-0.6362392226649662,-0.9097905400273109,0.8322262551325478,0.7150999985878068,0.06279828060143189,-0.412958796825298,1.4329258820598159,-0.8637791771530676,-1.0954913801193207,-0.06480379588709152,0.3949453920319386,0.31303318522898527,-0.022088097488964575,-0.546410842239735
3,367
Disinhibition
18
56
2.610865
0.009031
Q9NZ01,Q709C8,P19022,P42858,Q04637,P17480,Q6P1N0,Q96N66,Q9NUQ7,Q96F07,P05067,Q13501,P49815,Q9ULK4,Q2M389,P26358,O75165,O96008
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
336,200,214,100,515,439,376,144,315,111,14,234,546,355,52,176,300,271
1227,300,271,841,14,1991,439,214,1384,176,1319,3177,100,2913,2740,546,2916,2262,2741,796,978,515,2813,2182,2744,1250,2453,1490,234,1776,1604,1692,52,376,2190,919,1865,200,609,2293,993,1877,1275,111,1798,144,1074,816,2207,2480,1281,2403,315,336,3055,355
0.14695211780225223,0.9860724317343753,1.0620389315076852,0.3949453920319386,4.815860976496678,-0.23746346936348223,0.754312439228042,1.212138715175788,0.06279828060143189,1.3598932144259221,0.10496721166567786,-1.142327166182432,1.7549981936289338,-0.7722577547913748,-0.6362392226649662,0.6361522503407359,-0.7722577547913748,-0.36882191692968064,-0.6362392226649662,0.4356160170646649,0.31303318522898527,0.6757140740040977,-0.6814093200124656,-0.3248598804887178,-0.6362392226649662,0.14695211780225223,-0.4572697498231123,0.020446217421404334,1.1748381597601374,-0.10770002139860704,-0.022088097488964575,-0.06480379588709152,2.6970172924945244,0.8709321917690549,-0.3248598804887178,0.3540841185619894,-0.15077592925131486,1.2863020037686608,0.5964120554641071,-0.36882191692968064,0.31303318522898527,-0.15077592925131486,0.14695211780225223,1.6843250163853651,-0.10770002139860704,1.5054130123499248,0.27179356591045745,0.4356160170646649,-0.3248598804887178,-0.4572697498231123,0.14695211780225223,-0.412958796825298,0.9860724317343753,0.9478531474732188,-0.9097905400273109,0.909473770504105
3,367
Nonimmune hydrops fetalis
9
29
2.605881
0.009164
P10619,Q14739,Q07020,P62899,P61313,P62847,P18077,P42766,P61353
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
68,38,134,198,74,197,165,177,275
1560,1459,2654,841,1378,1230,68,165,3095,177,292,3227,851,910,74,275,1054,680,855,197,1681,198,2264,134,38,924,1530,3291,1719
-0.022088097488964575,0.020446217421404334,-0.5912394888767456,0.3949453920319386,0.06279828060143189,0.14695211780225223,2.1690444425785262,1.3964785412072227,-1.0023112020703986,1.3598932144259221,1.0241336866990407,-1.2838097038521317,0.3949453920319386,0.3540841185619894,2.0670777141599412,1.0620389315076852,0.27179356591045745,0.51638636702171,0.3949453920319386,1.2863020037686608,-0.06480379588709152,1.2863020037686608,-0.36882191692968064,1.5414559276361184,3.1701628794451158,0.3540841185619894,0.020446217421404334,-1.52282763066264,-0.06480379588709152
3,367
Aggressive behavior
7
89
2.602942
0.009243
Q9UBM7,P41229,O75503,Q15125,O00462,P54802,Q8WYQ5
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
1,33,3,7,40,54,87
2235,40,2497,2573,1099,3,358,466,439,1384,1670,2258,1474,2439,2509,1914,1388,3128,33,100,2740,546,599,2086,1325,3270,2005,1588,54,2262,1591,972,978,1183,3130,2813,2182,1772,2963,797,2868,2092,234,1251,1254,1060,2457,7,1692,2024,1260,3246,2028,2280,1864,1865,609,1197,1866,2293,2197,993,87,2549,311,1877,2550,925,1350,1799,996,1637,816,930,2207,1714,1281,2629,2403,426,2776,3082,1896,1,3167,3023,2567,889,2717
-0.36882191692968064,3.1081955602316613,-0.5017540153159744,-0.546410842239735,0.23036622014532987,5.682423722639393,0.8709321917690549,0.7150999985878068,0.754312439228042,0.06279828060143189,-0.06480379588709152,-0.36882191692968064,0.020446217421404334,-0.4572697498231123,-0.5017540153159744,-0.1940306860173823,0.06279828060143189,-1.0488191777371687,3.3236578103542245,1.7549981936289338,-0.6362392226649662,0.6361522503407359,0.5964120554641071,-0.2810734678085235,0.10496721166567786,-1.426742025084107,-0.23746346936348223,-0.022088097488964575,2.664757267155283,-0.36882191692968064,-0.022088097488964575,0.31303318522898527,0.31303318522898527,0.18875209347989597,-1.0488191777371687,-0.6814093200124656,-0.3248598804887178,-0.10770002139860704,-0.8179346882917339,0.4356160170646649,-0.7267490661171271,-0.2810734678085235,1.1748381597601374,0.14695211780225223,0.14695211780225223,0.27179356591045745,-0.4572697498231123,5.347423495313898,-0.06480379588709152,-0.23746346936348223,0.14695211780225223,-1.3312935370263337,-0.23746346936348223,-0.36882191692968064,-0.15077592925131486,-0.15077592925131486,0.5964120554641071,0.18875209347989597,-0.15077592925131486,-0.36882191692968064,-0.3248598804887178,0.31303318522898527,1.9641025522127773,-0.5017540153159744,0.9860724317343753,-0.15077592925131486,-0.5017540153159744,0.3540841185619894,0.10496721166567786,-0.10770002139860704,0.31303318522898527,-0.022088097488964575,0.4356160170646649,0.3540841185619894,-0.3248598804887178,-0.06480379588709152,0.14695211780225223,-0.546410842239735,-0.412958796825298,0.7933537558921767,-0.6362392226649662,-0.9559681035265681,-0.15077592925131486,6.354521266861696,-1.0954913801193207,-0.8637791771530676,-0.5017540153159744,0.3949453920319386,-0.5912394888767456
3,367
Cellular lipid catabolic process
11
62
2.601175
0.00929
P50897,P04066,P07686,Q13510,P17900,Q8NHP8,P06865,Q2T9J0,P06280,P11310,Q8NCC3
Processes and pathways
GO Biological process
msigdb_gobp
35,6,103,104,46,15,47,92,23,91,60
664,1163,1821,1298,1101,1373,3147,3278,668,2247,841,6,1035,965,23,47,103,3174,91,2905,46,1472,2993,2437,2799,2859,258,2802,1996,1477,361,2954,2354,1236,3069,2003,1393,35,2363,2176,2268,3365,104,2674,1407,2820,3216,92,1696,2610,1348,333,60,15,110,2202,1714,759,1002,3190,493,1546
0.51638636702171,0.18875209347989597,-0.15077592925131486,0.10496721166567786,0.23036622014532987,0.06279828060143189,-1.0954913801193207,-1.4747054833332776,0.51638636702171,-0.36882191692968064,0.3949453920319386,5.477203395245907,0.27179356591045745,0.31303318522898527,3.860476447122193,2.9518057266228475,1.719723884747831,-1.142327166182432,1.8948765913387664,-0.7722577547913748,3.014617485988229,0.020446217421404334,-0.8637791771530676,-0.4572697498231123,-0.6814093200124656,-0.7267490661171271,1.099790142352336,-0.6814093200124656,-0.23746346936348223,0.020446217421404334,0.8709321917690549,-0.8179346882917339,-0.412958796825298,0.14695211780225223,-0.9559681035265681,-0.23746346936348223,0.06279828060143189,3.2625005214835268,-0.412958796825298,-0.3248598804887178,-0.36882191692968064,-8.898651371343082,1.719723884747831,-0.5912394888767456,0.06279828060143189,-0.6814093200124656,-1.2364869532593843,1.8948765913387664,-0.06480379588709152,-0.546410842239735,0.10496721166567786,0.9478531474732188,2.3368292667835435,4.815860976496678,1.6843250163853651,-0.3248598804887178,-0.06480379588709152,0.4760956266149155,0.31303318522898527,-1.142327166182432,0.7150999985878068,0.020446217421404334
3,367
Oxidoreductase activity acting on the ch ch group of donors nad or nadp as acceptor
6
12
2.597961
0.009378
Q15392,Q9UBM7,Q14739,Q8N4Q0,P30043,Q14914
Functions
GO Molecular function
msigdb_gomf
0,1,38,12,228,329
228,3152,597,2173,38,329,0,12,3320,3142,336,1
1.1748381597601374,-1.0954913801193207,0.5964120554641071,-0.3248598804887178,3.1701628794451158,0.9478531474732188,9.266342596549883,5.110752473018885,-1.8148607923698326,-1.0488191777371687,0.9478531474732188,6.354521266861696
3,367
Neuron apoptotic process
11
50
2.597847
0.009381
P50897,O95630,Q99720,P04179,P42574,P05067,P48507,Q99538,Q9H2P0,Q92542,O14786
Processes and pathways
GO Biological process
msigdb_gobp
35,437,37,464,260,14,417,20,426,159,127
626,127,1105,1376,2792,437,2068,841,464,1568,2582,14,3065,2157,2071,1908,503,1572,1477,1914,260,1917,1919,2444,1320,417,2357,597,2913,35,1325,1586,1117,1592,1330,3154,2091,1402,1692,159,1517,1628,3321,2480,20,37,426,2128,1650,952
0.5564909583357176,1.5773671103553362,0.23036622014532987,0.06279828060143189,-0.6814093200124656,0.754312439228042,-0.2810734678085235,0.3949453920319386,0.7150999985878068,-0.022088097488964575,-0.546410842239735,4.815860976496678,-0.9559681035265681,-0.3248598804887178,-0.2810734678085235,-0.1940306860173823,0.6757140740040977,-0.022088097488964575,0.020446217421404334,-0.1940306860173823,1.099790142352336,-0.1940306860173823,-0.1940306860173823,-0.4572697498231123,0.10496721166567786,0.7933537558921767,-0.412958796825298,0.5964120554641071,-0.7722577547913748,3.2625005214835268,0.10496721166567786,-0.022088097488964575,0.23036622014532987,-0.022088097488964575,0.10496721166567786,-1.0954913801193207,-0.2810734678085235,0.06279828060143189,-0.06480379588709152,1.4329258820598159,0.020446217421404334,-0.022088097488964575,-1.8148607923698326,-0.4572697498231123,3.9186948792031995,3.201023198065498,0.7933537558921767,-0.2810734678085235,-0.022088097488964575,0.3540841185619894
3,367
Viral myocarditis
8
12
2.594642
0.009469
P10321,Q04637,P04439,P42574,P01889,P35580,Q14118,P35579
Processes and pathways
KEGG Pathways
msigdb_kegg
213,515,73,260,84,387,327,245
584,84,73,213,245,387,260,1245,976,515,327,2191
0.5964120554641071,1.9985415804284918,2.1011771507196184,1.212138715175788,1.1373892537486945,0.8322262551325478,1.099790142352336,0.14695211780225223,0.31303318522898527,0.6757140740040977,0.9478531474732188,-0.3248598804887178
3,367
Tertiary granule
10
42
2.592554
0.009527
Q7L576,Q9Y2Q5,P11279,Q13510,Q92820,P63167,P13473,P10253,P27105,P42785
Localization
GO Cellular component
msigdb_gocc
263,136,90,104,77,277,26,59,62,31
2330,1103,1738,3278,786,1463,3149,2854,2505,59,90,26,2588,2345,62,2443,2738,31,2365,1243,2960,1245,277,2670,104,800,420,309,1947,690,263,1510,1624,77,923,1878,2301,1881,2313,3024,136,2647
-0.412958796825298,0.23036622014532987,-0.10770002139860704,-1.4747054833332776,0.4356160170646649,0.020446217421404334,-1.0954913801193207,-0.7267490661171271,-0.5017540153159744,2.4362503004565204,1.8948765913387664,3.713721512871941,-0.546410842239735,-0.412958796825298,2.270032897213297,-0.4572697498231123,-0.6362392226649662,3.4450326941058216,-0.412958796825298,0.14695211780225223,-0.8179346882917339,0.14695211780225223,1.0620389315076852,-0.5912394888767456,1.719723884747831,0.4356160170646649,0.7933537558921767,0.9860724317343753,-0.1940306860173823,0.51638636702171,1.099790142352336,0.020446217421404334,-0.022088097488964575,2.0670777141599412,0.3540841185619894,-0.15077592925131486,-0.36882191692968064,-0.15077592925131486,-0.36882191692968064,-0.8637791771530676,1.5414559276361184,-0.546410842239735
3,367
CD markers
8
15
2.587723
0.009661
P19022,P02786,P11279,P35613,P11717,Q07954,P13473,O14786
Functions
Protein Atlas Protein class
protein_atlas_protein_class
214,67,90,305,53,120,26,127
127,2243,67,1309,3340,1464,90,53,26,214,305,342,511,120,775
1.5773671103553362,-0.36882191692968064,2.202814512277326,0.10496721166567786,-2.3646418191340213,0.020446217421404334,1.8948765913387664,2.664757267155283,3.713721512871941,1.212138715175788,0.9860724317343753,0.909473770504105,0.6757140740040977,1.613148049789865,0.4760956266149155
3,367
Agitation
8
33
2.585523
0.009723
P48449,Q709C8,P42858,Q13501,P05067,P42892,O75165,O96008
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
215,200,100,234,14,16,300,271
300,2725,271,841,14,731,2072,1748,2799,361,1319,100,16,1918,215,3305,1325,2005,2262,978,515,1490,234,1604,1406,2188,2756,919,200,1423,1074,2480,1714
0.9860724317343753,-0.6362392226649662,1.0620389315076852,0.3949453920319386,4.815860976496678,0.4760956266149155,-0.2810734678085235,-0.10770002139860704,-0.6814093200124656,0.8709321917690549,0.10496721166567786,1.7549981936289338,4.4588127644301565,-0.1940306860173823,1.212138715175788,-1.6681404132370228,0.10496721166567786,-0.23746346936348223,-0.36882191692968064,0.31303318522898527,0.6757140740040977,0.020446217421404334,1.1748381597601374,-0.022088097488964575,0.06279828060143189,-0.3248598804887178,-0.6362392226649662,0.3540841185619894,1.2863020037686608,0.06279828060143189,0.27179356591045745,-0.4572697498231123,-0.06480379588709152
3,367
Leishmania infection
10
39
2.580827
0.009856
Q7L576,O15143,Q14185,Q13459,Q12965,Q96F07,P05067,Q9Y4I1,Q9UQB8,P35579
Processes and pathways
Reactome Pathways
msigdb_reactome
263,338,101,262,261,111,14,287,29,245
407,1369,338,2786,2143,900,14,2071,2340,1908,1748,2730,1472,3126,1670,245,2263,1117,3097,2370,1055,2012,1245,1483,2962,261,262,101,2025,263,2037,111,1278,2225,29,661,2231,949,287
0.7933537558921767,0.06279828060143189,0.909473770504105,-0.6814093200124656,-0.3248598804887178,0.3540841185619894,4.815860976496678,-0.2810734678085235,-0.412958796825298,-0.1940306860173823,-0.10770002139860704,-0.6362392226649662,0.020446217421404334,-1.0488191777371687,-0.06480379588709152,1.1373892537486945,-0.36882191692968064,0.23036622014532987,-1.0023112020703986,-0.412958796825298,0.27179356591045745,-0.23746346936348223,0.14695211780225223,0.020446217421404334,-0.8179346882917339,1.099790142352336,1.099790142352336,1.7549981936289338,-0.23746346936348223,1.099790142352336,-0.23746346936348223,1.6843250163853651,0.14695211780225223,-0.3248598804887178,3.535260987655072,0.5564909583357176,-0.3248598804887178,0.3540841185619894,1.0620389315076852
3,367
Lipid metabolism
16
127
2.576041
0.009994
Q15392,Q9UBM7,Q14739,Q15125,Q13510,Q8N2A8,Q96N66,Q96G23,Q8NHP8,P17900,P07602,O15118,P61916,P11310,Q8NCC3,P37268
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
0,1,38,7,104,142,144,143,15,46,17,81,25,91,60,30
664,2060,2495,1163,954,1821,1452,1298,81,1101,1025,1659,1823,2499,2501,668,1663,411,2247,463,2070,841,1035,17,3174,2854,91,467,2731,46,1472,1832,2437,2799,2859,3333,2802,1996,2995,1579,361,635,30,2000,2168,2354,1236,3069,415,3152,215,793,597,2003,1393,908,2596,2363,1114,1762,1679,2176,2807,25,1329,2090,1686,3339,1185,3131,3365,1118,645,104,1602,1122,1252,38,329,2674,520,7,3075,984,0,2024,446,3216,157,986,688,1193,1696,557,2610,142,1348,1269,60,2758,15,3249,485,223,3322,143,144,3050,2767,1714,759,881,1639,1962,826,3142,3083,2312,336,767,1,622,831,2713,1546,534,2141
0.51638636702171,-0.2810734678085235,-0.5017540153159744,0.18875209347989597,0.31303318522898527,-0.15077592925131486,0.020446217421404334,0.10496721166567786,2.032866242545018,0.23036622014532987,0.27179356591045745,-0.06480379588709152,-0.15077592925131486,-0.5017540153159744,-0.5017540153159744,0.51638636702171,-0.06480379588709152,0.7933537558921767,-0.36882191692968064,0.7150999985878068,-0.2810734678085235,0.3949453920319386,0.27179356591045745,4.3750256940936305,-1.142327166182432,-0.7267490661171271,1.8948765913387664,0.7150999985878068,-0.6362392226649662,3.014617485988229,0.020446217421404334,-0.15077592925131486,-0.4572697498231123,-0.6814093200124656,-0.7267490661171271,-2.1124650811200967,-0.6814093200124656,-0.23746346936348223,-0.8637791771530676,-0.022088097488964575,0.8709321917690549,0.5564909583357176,3.4751842548839553,-0.23746346936348223,-0.3248598804887178,-0.412958796825298,0.14695211780225223,-0.9559681035265681,0.7933537558921767,-1.0954913801193207,1.212138715175788,0.4356160170646649,0.5964120554641071,-0.23746346936348223,0.06279828060143189,0.3540841185619894,-0.546410842239735,-0.412958796825298,0.23036622014532987,-0.10770002139860704,-0.06480379588709152,-0.3248598804887178,-0.6814093200124656,3.772633277255873,0.10496721166567786,-0.2810734678085235,-0.06480379588709152,-2.3139063625418146,0.18875209347989597,-1.0488191777371687,-8.898651371343082,0.23036622014532987,0.5564909583357176,1.719723884747831,-0.022088097488964575,0.23036622014532987,0.14695211780225223,3.1701628794451158,0.9478531474732188,-0.5912394888767456,0.6757140740040977,5.347423495313898,-0.9559681035265681,0.31303318522898527,9.266342596549883,-0.23746346936348223,0.754312439228042,-1.2364869532593843,1.4329258820598159,0.31303318522898527,0.51638636702171,0.18875209347989597,-0.06480379588709152,0.6361522503407359,-0.546410842239735,1.5054130123499248,0.10496721166567786,0.14695211780225223,2.3368292667835435,-0.6362392226649662,4.815860976496678,-1.3312935370263337,0.7150999985878068,1.212138715175788,-1.8148607923698326,1.5054130123499248,1.5054130123499248,-0.9097905400273109,-0.6362392226649662,-0.06480379588709152,0.4760956266149155,0.3949453920319386,-0.022088097488964575,-0.1940306860173823,0.4356160170646649,-1.0488191777371687,-0.9559681035265681,-0.36882191692968064,0.9478531474732188,0.4760956266149155,6.354521266861696,0.5964120554641071,0.4356160170646649,-0.5912394888767456,0.020446217421404334,0.6757140740040977,-0.2810734678085235
3,367
Abnormal autonomic nervous system physiology
7
37
2.573433
0.01007
P35251,P07686,Q99996,P42892,P07602,P06280,Q9NZJ7
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
153,103,79,16,17,23,162
497,1301,1029,300,2792,2337,841,23,17,103,413,3240,153,2355,16,3178,1325,2091,515,2182,1334,2674,2756,919,200,876,1277,1074,816,2480,79,2774,1722,162,950,2717,837
0.6757140740040977,0.10496721166567786,0.27179356591045745,0.9860724317343753,-0.6814093200124656,-0.412958796825298,0.3949453920319386,3.860476447122193,4.3750256940936305,1.719723884747831,0.7933537558921767,-1.3312935370263337,1.4329258820598159,-0.412958796825298,4.4588127644301565,-1.142327166182432,0.10496721166567786,-0.2810734678085235,0.6757140740040977,-0.3248598804887178,0.10496721166567786,-0.5912394888767456,-0.6362392226649662,0.3540841185619894,1.2863020037686608,0.3949453920319386,0.14695211780225223,0.27179356591045745,0.4356160170646649,-0.4572697498231123,2.0670777141599412,-0.6362392226649662,-0.06480379588709152,1.4329258820598159,0.3540841185619894,-0.5912394888767456,0.4356160170646649
3,367
Diseases of metabolism
15
44
2.567627
0.01024
Q2TAA5,P10619,P07686,Q14118,P16278,P11498,P15586,P06865,Q96RQ3,P48507,O43505,P54802,P10253,P50747,O75352
Processes and pathways
Reactome Pathways
msigdb_reactome
169,68,103,327,164,467,13,47,312,417,537,54,59,547,184
537,2651,3277,184,3278,1035,965,47,103,59,68,467,1910,13,164,1575,1832,1177,3038,2738,2259,596,1320,417,3228,547,1482,1324,54,2091,1599,1118,1494,327,169,2689,1351,927,312,1141,1530,2127,2490,2897
0.6361522503407359,-0.5912394888767456,-1.4747054833332776,1.3231682601538646,-1.4747054833332776,0.27179356591045745,0.31303318522898527,2.9518057266228475,1.719723884747831,2.4362503004565204,2.1690444425785262,0.7150999985878068,-0.1940306860173823,4.896921049154351,1.3964785412072227,-0.022088097488964575,-0.15077592925131486,0.18875209347989597,-0.9097905400273109,-0.6362392226649662,-0.36882191692968064,0.5964120554641071,0.10496721166567786,0.7933537558921767,-1.2838097038521317,0.6361522503407359,0.020446217421404334,0.10496721166567786,2.664757267155283,-0.2810734678085235,-0.022088097488964575,0.23036622014532987,0.020446217421404334,0.9478531474732188,1.3964785412072227,-0.5912394888767456,0.10496721166567786,0.3540841185619894,0.9860724317343753,0.23036622014532987,0.020446217421404334,-0.2810734678085235,-0.4572697498231123,-0.7267490661171271
3,367
Abnormality of bone mineral density
26
135
2.563396
0.010365
Q15392,Q15125,P07602,Q9H490,P06280,Q14108,Q9NZJ7,Q14739,P16278,O00754,Q9NUQ7,Q93008,P51798,P54802,O75531,Q9HC21,Q15043,P27635,Q96HA7,Q14692,Q9NZC9,O00170,Q13510,Q13501,Q9H9Y6,Q8IY37
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
0,7,17,284,23,27,162,38,164,44,315,311,307,54,301,192,330,195,349,346,97,337,104,234,383,251
3089,337,1225,44,433,497,2984,840,2331,2787,2576,1104,960,1228,1980,1031,301,3238,1904,1743,2903,2068,1377,3148,841,1035,965,1378,23,1169,3193,1037,17,1748,1040,790,2904,164,1174,1042,671,1109,2949,1994,195,1234,2165,1914,1580,2000,3067,636,2513,793,2360,2363,307,2999,2864,54,1589,2262,602,2520,1846,2599,2264,2089,3180,1183,742,682,367,2524,1600,1400,1119,1120,234,104,27,1856,346,38,802,1779,330,3302,7,2096,0,1497,2750,521,2533,2534,1408,3247,1949,251,1624,993,1205,311,1517,2038,349,1523,927,1075,530,821,569,2308,1717,284,2936,383,192,1361,2563,3085,315,765,2134,97,162,3209,710,3192,2642,1295,774,837,3027
-1.0023112020703986,0.909473770504105,0.14695211780225223,3.014617485988229,0.754312439228042,0.6757140740040977,-0.8637791771530676,0.3949453920319386,-0.412958796825298,-0.6814093200124656,-0.546410842239735,0.23036622014532987,0.31303318522898527,0.14695211780225223,-0.23746346936348223,0.27179356591045745,0.9860724317343753,-1.3312935370263337,-0.1940306860173823,-0.10770002139860704,-0.7722577547913748,-0.2810734678085235,0.06279828060143189,-1.0954913801193207,0.3949453920319386,0.27179356591045745,0.31303318522898527,0.06279828060143189,3.860476447122193,0.18875209347989597,-1.1893259001279373,0.27179356591045745,4.3750256940936305,-0.10770002139860704,0.27179356591045745,0.4356160170646649,-0.7722577547913748,1.3964785412072227,0.18875209347989597,0.27179356591045745,0.51638636702171,0.23036622014532987,-0.8179346882917339,-0.23746346936348223,1.2863020037686608,0.14695211780225223,-0.3248598804887178,-0.1940306860173823,-0.022088097488964575,-0.23746346936348223,-0.9559681035265681,0.5564909583357176,-0.5017540153159744,0.4356160170646649,-0.412958796825298,-0.412958796825298,0.9860724317343753,-0.8637791771530676,-0.7267490661171271,2.664757267155283,-0.022088097488964575,-0.36882191692968064,0.5964120554641071,-0.5017540153159744,-0.15077592925131486,-0.546410842239735,-0.36882191692968064,-0.2810734678085235,-1.142327166182432,0.18875209347989597,0.4760956266149155,0.51638636702171,0.8709321917690549,-0.5017540153159744,-0.022088097488964575,0.06279828060143189,0.23036622014532987,0.23036622014532987,1.1748381597601374,1.719723884747831,3.6248188309031892,-0.15077592925131486,0.909473770504105,3.1701628794451158,0.4356160170646649,-0.10770002139860704,0.9478531474732188,-1.6195456688999854,5.347423495313898,-0.2810734678085235,9.266342596549883,0.020446217421404334,-0.6362392226649662,0.6757140740040977,-0.5017540153159744,-0.5017540153159744,0.06279828060143189,-1.3312935370263337,-0.1940306860173823,1.1373892537486945,-0.022088097488964575,0.31303318522898527,0.18875209347989597,0.9860724317343753,0.020446217421404334,-0.23746346936348223,0.909473770504105,0.020446217421404334,0.3540841185619894,0.27179356591045745,0.6757140740040977,0.4356160170646649,0.6361522503407359,-0.36882191692968064,-0.06480379588709152,1.0620389315076852,-0.7722577547913748,0.8709321917690549,1.3231682601538646,0.10496721166567786,-0.5017540153159744,-0.9559681035265681,0.9860724317343753,0.4760956266149155,-0.2810734678085235,1.8251785328251016,1.4329258820598159,-1.1893259001279373,0.51638636702171,-1.142327166182432,-0.546410842239735,0.14695211780225223,0.4760956266149155,0.4356160170646649,-0.8637791771530676
3,367
Abnormal oral mucosa morphology
12
68
2.561464
0.010423
Q15392,Q9UBM7,Q9H7D7,Q14739,Q13155,P16278,O00754,Q93008,P78527,P01889,Q14108,P53634
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
0,1,268,38,325,164,44,311,113,84,27,274
3089,408,44,1104,1228,2652,1980,1565,2903,84,841,3193,1748,2588,164,3240,2348,1580,636,1049,509,597,546,2362,274,1846,2089,113,1183,1184,1185,2962,2268,2524,325,2376,1058,27,38,606,3302,2096,0,371,2533,2534,2753,1409,3248,1864,1949,2542,1203,2300,311,1278,2041,530,268,1361,2134,944,1,710,2642,952,774,2897
-1.0023112020703986,0.7933537558921767,3.014617485988229,0.23036622014532987,0.14695211780225223,-0.5912394888767456,-0.23746346936348223,-0.022088097488964575,-0.7722577547913748,1.9985415804284918,0.3949453920319386,-1.1893259001279373,-0.10770002139860704,-0.546410842239735,1.3964785412072227,-1.3312935370263337,-0.412958796825298,-0.022088097488964575,0.5564909583357176,0.27179356591045745,0.6757140740040977,0.5964120554641071,0.6361522503407359,-0.412958796825298,1.0620389315076852,-0.15077592925131486,-0.2810734678085235,1.6488002071649115,0.18875209347989597,0.18875209347989597,0.18875209347989597,-0.8179346882917339,-0.36882191692968064,-0.5017540153159744,0.9478531474732188,-0.412958796825298,0.27179356591045745,3.6248188309031892,3.1701628794451158,0.5964120554641071,-1.6195456688999854,-0.2810734678085235,9.266342596549883,0.8709321917690549,-0.5017540153159744,-0.5017540153159744,-0.6362392226649662,0.06279828060143189,-1.3312935370263337,-0.15077592925131486,-0.1940306860173823,-0.5017540153159744,0.18875209347989597,-0.36882191692968064,0.9860724317343753,0.14695211780225223,-0.23746346936348223,0.6757140740040977,1.099790142352336,0.10496721166567786,-0.2810734678085235,0.3540841185619894,6.354521266861696,0.51638636702171,-0.546410842239735,0.3540841185619894,0.4760956266149155,-0.7267490661171271
3,367
Abnormal form of the vertebral bodies
15
86
2.56097
0.010438
Q9UBM7,Q9NZC9,Q99575,Q14739,P04066,Q15125,P16278,O00754,P15586,Q9NUQ7,Q12768,Q8IY37,P54802,P51798,Q96HA7
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
1,97,266,38,6,7,164,44,13,315,121,251,54,307,349
3089,337,1225,44,497,840,3211,2576,1104,895,960,1902,1167,3278,1743,2068,1377,6,1037,1748,13,164,2991,732,2348,1109,3241,1043,2165,1580,2082,1581,3314,3095,906,3257,2360,307,3352,54,1846,1683,2089,3000,1183,682,1772,121,1774,1119,2376,38,1690,3302,7,1780,1497,521,2533,2534,2606,2822,1343,251,811,1624,2038,349,1523,1353,927,266,1889,2308,2484,315,97,1,3022,2980,710,2982,662,3117,2642,774
-1.0023112020703986,0.909473770504105,0.14695211780225223,3.014617485988229,0.6757140740040977,0.3949453920319386,-1.2364869532593843,-0.546410842239735,0.23036622014532987,0.3540841185619894,0.31303318522898527,-0.1940306860173823,0.18875209347989597,-1.4747054833332776,-0.10770002139860704,-0.2810734678085235,0.06279828060143189,5.477203395245907,0.27179356591045745,-0.10770002139860704,4.896921049154351,1.3964785412072227,-0.8637791771530676,0.4760956266149155,-0.412958796825298,0.23036622014532987,-1.3312935370263337,0.27179356591045745,-0.3248598804887178,-0.022088097488964575,-0.2810734678085235,-0.022088097488964575,-1.7657985305992057,-1.0023112020703986,0.3540841185619894,-1.378937844623164,-0.412958796825298,0.9860724317343753,-2.6721680762670923,2.664757267155283,-0.15077592925131486,-0.06480379588709152,-0.2810734678085235,-0.8637791771530676,0.18875209347989597,0.51638636702171,-0.10770002139860704,1.613148049789865,-0.10770002139860704,0.23036622014532987,-0.412958796825298,3.1701628794451158,-0.06480379588709152,-1.6195456688999854,5.347423495313898,-0.10770002139860704,0.020446217421404334,0.6757140740040977,-0.5017540153159744,-0.5017540153159744,-0.546410842239735,-0.6814093200124656,0.10496721166567786,1.1373892537486945,0.4356160170646649,-0.022088097488964575,-0.23746346936348223,0.909473770504105,0.020446217421404334,0.10496721166567786,0.3540841185619894,1.099790142352336,-0.15077592925131486,-0.36882191692968064,-0.4572697498231123,0.9860724317343753,1.8251785328251016,6.354521266861696,-0.8637791771530676,-0.8179346882917339,0.51638636702171,-0.8179346882917339,0.5564909583357176,-1.0023112020703986,-0.546410842239735,0.4760956266149155
3,367
Diarrhea
9
73
2.547974
0.010835
P02786,P07686,P15586,P42892,Q15904,P01889,P54802,P06280,P11310
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
67,103,13,16,48,84,54,23,91
1029,2651,2722,2652,2337,2247,728,84,67,2582,23,103,2853,1465,91,13,1042,732,2949,2799,1474,3038,361,3039,1999,2000,2168,2354,2513,3315,16,906,1393,735,2362,54,1843,1846,1184,1185,1250,391,2376,104,1058,1940,2273,2457,2096,2459,48,3216,688,2104,377,200,1949,3182,2926,1625,1205,1877,754,1517,2930,1353,2480,2704,1530,1717,2567,2942,952
0.27179356591045745,-0.5912394888767456,-0.6362392226649662,-0.5912394888767456,-0.412958796825298,-0.36882191692968064,0.4760956266149155,1.9985415804284918,2.202814512277326,-0.546410842239735,3.860476447122193,1.719723884747831,-0.7267490661171271,0.020446217421404334,1.8948765913387664,4.896921049154351,0.27179356591045745,0.4760956266149155,-0.8179346882917339,-0.6814093200124656,0.020446217421404334,-0.9097905400273109,0.8709321917690549,-0.9097905400273109,-0.23746346936348223,-0.23746346936348223,-0.3248598804887178,-0.412958796825298,-0.5017540153159744,-1.7657985305992057,4.4588127644301565,0.3540841185619894,0.06279828060143189,0.4760956266149155,-0.412958796825298,2.664757267155283,-0.15077592925131486,-0.15077592925131486,0.18875209347989597,0.18875209347989597,0.14695211780225223,0.8322262551325478,-0.412958796825298,1.719723884747831,0.27179356591045745,-0.1940306860173823,-0.36882191692968064,-0.4572697498231123,-0.2810734678085235,-0.4572697498231123,2.888645998928826,-1.2364869532593843,0.51638636702171,-0.2810734678085235,0.8709321917690549,1.2863020037686608,-0.1940306860173823,-1.142327166182432,-0.7722577547913748,-0.022088097488964575,0.18875209347989597,-0.15077592925131486,0.4760956266149155,0.020446217421404334,-0.7722577547913748,0.10496721166567786,-0.4572697498231123,-0.5912394888767456,0.020446217421404334,-0.06480379588709152,-0.5017540153159744,-0.7722577547913748,0.3540841185619894
3,367
Endoribonuclease activity
8
28
2.54303
0.01099
Q9BSV6,Q99575,Q9ULX3,Q9BRJ7,Q8N2A8,O00584,P27695,Q96DE0
Functions
GO Molecular function
msigdb_gomf
334,266,72,106,142,18,304,28
18,1557,3173,587,667,540,304,1180,909,322,1596,1129,2687,1267,142,28,1798,266,1282,1529,106,334,1152,2414,72,1015,3233,3026
4.120355977593298,-0.022088097488964575,-1.142327166182432,0.5964120554641071,0.51638636702171,0.6361522503407359,0.9860724317343753,0.18875209347989597,0.3540841185619894,0.9478531474732188,-0.022088097488964575,0.23036622014532987,-0.5912394888767456,0.14695211780225223,1.5054130123499248,3.535260987655072,-0.10770002139860704,1.099790142352336,0.14695211780225223,0.020446217421404334,1.719723884747831,0.9478531474732188,0.23036622014532987,-0.412958796825298,2.1351656880009666,0.31303318522898527,-1.2838097038521317,-0.8637791771530676
3,367
Coarctation of aorta
11
41
2.542852
0.010995
Q9UBM7,P19022,Q9Y4A5,Q07020,Q14839,P62899,P61313,P62847,P18077,P42766,P61353
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
1,214,174,134,199,198,74,197,165,177,275
2719,1226,2788,1230,165,214,2259,3095,177,292,3227,1588,1930,851,910,74,275,1054,2742,680,855,197,1681,198,2264,742,2815,134,2376,199,1188,2924,1865,811,924,3082,1,2980,624,174,2418
-0.6362392226649662,0.14695211780225223,-0.6814093200124656,0.14695211780225223,1.3964785412072227,1.212138715175788,-0.36882191692968064,-1.0023112020703986,1.3598932144259221,1.0241336866990407,-1.2838097038521317,-0.022088097488964575,-0.1940306860173823,0.3949453920319386,0.3540841185619894,2.0670777141599412,1.0620389315076852,0.27179356591045745,-0.6362392226649662,0.51638636702171,0.3949453920319386,1.2863020037686608,-0.06480379588709152,1.2863020037686608,-0.36882191692968064,0.4760956266149155,-0.6814093200124656,1.5414559276361184,-0.412958796825298,1.2863020037686608,0.18875209347989597,-0.7722577547913748,-0.15077592925131486,0.4356160170646649,0.3540841185619894,-0.9559681035265681,6.354521266861696,-0.8179346882917339,0.5964120554641071,1.3964785412072227,-0.412958796825298
3,367
Memory impairment
15
42
2.54241
0.011009
P42858,P15289,Q13501,P05067,Q8WVX9,P07602,P49770,P40692,P01889,P26358,Q9NZJ7,Q9NR50,Q14232,O96008,P52701
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
100,413,234,14,485,17,470,469,84,176,162,492,605,271,548
1301,271,728,84,14,17,2853,413,176,1997,469,100,1919,597,470,548,1841,2366,1589,2262,851,2182,2963,913,234,605,2531,688,1203,485,2550,1075,1280,492,944,162,1725,2567,2894,2490,2897,2493
0.10496721166567786,1.0620389315076852,0.4760956266149155,1.9985415804284918,4.815860976496678,4.3750256940936305,-0.7267490661171271,0.7933537558921767,1.3598932144259221,-0.23746346936348223,0.7150999985878068,1.7549981936289338,-0.1940306860173823,0.5964120554641071,0.7150999985878068,0.6361522503407359,-0.15077592925131486,-0.412958796825298,-0.022088097488964575,-0.36882191692968064,0.3949453920319386,-0.3248598804887178,-0.8179346882917339,0.3540841185619894,1.1748381597601374,0.5964120554641071,-0.5017540153159744,0.51638636702171,0.18875209347989597,0.7150999985878068,-0.5017540153159744,0.27179356591045745,0.14695211780225223,0.7150999985878068,0.3540841185619894,1.4329258820598159,-0.06480379588709152,-0.5017540153159744,-0.7267490661171271,-0.4572697498231123,-0.7267490661171271,-0.4572697498231123
3,367
Rigidity
12
53
2.541292
0.011044
Q15392,Q709C8,P42858,P17480,P04350,P16278,P15289,Q96F07,Q9Y4I1,P07602,O75165,Q9NZJ7
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
0,200,100,439,465,164,413,111,287,17,300,162
1974,1301,300,3173,1985,841,465,17,1040,413,164,439,2162,1478,1388,2861,3177,100,2913,1322,1325,2005,1590,2741,796,515,2813,2182,2744,1687,1604,0,2756,919,200,1792,2202,2206,1424,111,1074,1075,2480,2769,2049,162,2894,1220,950,2232,2717,287,2493
-0.23746346936348223,0.10496721166567786,0.9860724317343753,-1.142327166182432,-0.23746346936348223,0.3949453920319386,0.7150999985878068,4.3750256940936305,0.27179356591045745,0.7933537558921767,1.3964785412072227,0.754312439228042,-0.3248598804887178,0.020446217421404334,0.06279828060143189,-0.7267490661171271,-1.142327166182432,1.7549981936289338,-0.7722577547913748,0.10496721166567786,0.10496721166567786,-0.23746346936348223,-0.022088097488964575,-0.6362392226649662,0.4356160170646649,0.6757140740040977,-0.6814093200124656,-0.3248598804887178,-0.6362392226649662,-0.06480379588709152,-0.022088097488964575,9.266342596549883,-0.6362392226649662,0.3540841185619894,1.2863020037686608,-0.10770002139860704,-0.3248598804887178,-0.3248598804887178,0.06279828060143189,1.6843250163853651,0.27179356591045745,0.27179356591045745,-0.4572697498231123,-0.6362392226649662,-0.23746346936348223,1.4329258820598159,-0.7267490661171271,0.18875209347989597,0.3540841185619894,-0.3248598804887178,-0.5912394888767456,1.0620389315076852,-0.4572697498231123
3,367
Myosin head, motor domain [IPR001609]
7
10
2.535681
0.011223
Q13459,Q12965,O94832,O43795,Q9Y4I1,P35580,P35579
Sequence
InterPro Domain
interpro_domain
262,261,319,206,287,387,245
407,206,319,245,387,261,262,2191,890,287
0.7933537558921767,1.249292736644776,0.9478531474732188,1.1373892537486945,0.8322262551325478,1.099790142352336,1.099790142352336,-0.3248598804887178,0.3949453920319386,1.0620389315076852
3,367
Carboxylic acid transport
12
29
2.532303
0.011332
P80404,O95563,P53985,P30825,P28288,P07602,Q15041,Q9H2D1,P14174,Q9UBX3,Q9NZJ7,O14745
Processes and pathways
GO Biological process
msigdb_gobp
65,462,294,259,258,17,519,490,116,495,162,433
433,2848,1984,2428,462,2155,1309,17,1464,116,258,259,2355,510,294,2916,65,1248,645,519,1779,2677,1696,490,2976,2212,162,495,2567
0.754312439228042,-0.7267490661171271,-0.23746346936348223,-0.4572697498231123,0.7150999985878068,-0.3248598804887178,0.10496721166567786,4.3750256940936305,0.020446217421404334,1.613148049789865,1.099790142352336,1.099790142352336,-0.412958796825298,0.6757140740040977,1.0241336866990407,-0.7722577547913748,2.2364769766120918,0.14695211780225223,0.5564909583357176,0.6757140740040977,-0.10770002139860704,-0.5912394888767456,-0.06480379588709152,0.7150999985878068,-0.8179346882917339,-0.3248598804887178,1.4329258820598159,0.7150999985878068,-0.5017540153159744
3,367
Reduced consciousness confusion
33
133
2.529424
0.011425
Q9UBM7,Q07020,P05067,P07602,Q13423,Q15833,P60891,P61353,Q9NZJ7,O96008,P21953,P46777,O00754,P18077,P15289,Q96RQ3,P42766,P26358,Q9Y3D3,Q86Y39,Q9HC21,P80404,P62899,P61313,P62847,Q9NPL8,P01889,Q9BU61,Q9NR50,P11310,P11166,P42858,P35610
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
1,134,14,17,391,420,24,275,162,271,152,292,44,165,413,312,177,176,455,190,192,65,198,74,197,80,84,351,492,91,466,100,361
1656,3267,44,497,628,1301,1561,1901,538,1903,2791,2654,271,2069,728,84,841,14,1035,965,17,2853,2987,1230,2248,466,3125,91,1040,2905,413,1042,165,2658,671,1176,152,1575,1384,2437,2799,176,2859,2438,1474,1477,1914,1388,361,3039,1999,1581,2954,3095,636,2354,3128,177,100,1839,3152,292,3227,597,2003,470,1322,3096,1393,547,2362,2176,851,24,910,74,275,1054,680,855,197,1681,198,2264,65,134,2524,2963,913,391,605,1406,420,1407,3216,1788,190,3105,811,1203,3219,1205,2202,924,2550,2206,1351,2623,312,1075,1280,2702,351,1080,2976,192,2127,80,492,2133,1966,944,162,2486,1,1725,2567,2640,455,2897,837,2140,838
-0.06480379588709152,-1.426742025084107,3.014617485988229,0.6757140740040977,0.5564909583357176,0.10496721166567786,-0.022088097488964575,-0.1940306860173823,0.6361522503407359,-0.1940306860173823,-0.6814093200124656,-0.5912394888767456,1.0620389315076852,-0.2810734678085235,0.4760956266149155,1.9985415804284918,0.3949453920319386,4.815860976496678,0.27179356591045745,0.31303318522898527,4.3750256940936305,-0.7267490661171271,-0.8637791771530676,0.14695211780225223,-0.36882191692968064,0.7150999985878068,-1.0488191777371687,1.8948765913387664,0.27179356591045745,-0.7722577547913748,0.7933537558921767,0.27179356591045745,1.3964785412072227,-0.5912394888767456,0.51638636702171,0.18875209347989597,1.4329258820598159,-0.022088097488964575,0.06279828060143189,-0.4572697498231123,-0.6814093200124656,1.3598932144259221,-0.7267490661171271,-0.4572697498231123,0.020446217421404334,0.020446217421404334,-0.1940306860173823,0.06279828060143189,0.8709321917690549,-0.9097905400273109,-0.23746346936348223,-0.022088097488964575,-0.8179346882917339,-1.0023112020703986,0.5564909583357176,-0.412958796825298,-1.0488191777371687,1.3598932144259221,1.7549981936289338,-0.15077592925131486,-1.0954913801193207,1.0241336866990407,-1.2838097038521317,0.5964120554641071,-0.23746346936348223,0.7150999985878068,0.10496721166567786,-1.0023112020703986,0.06279828060143189,0.6361522503407359,-0.412958796825298,-0.3248598804887178,0.3949453920319386,3.8312646321143324,0.3540841185619894,2.0670777141599412,1.0620389315076852,0.27179356591045745,0.51638636702171,0.3949453920319386,1.2863020037686608,-0.06480379588709152,1.2863020037686608,-0.36882191692968064,2.2364769766120918,1.5414559276361184,-0.5017540153159744,-0.8179346882917339,0.3540841185619894,0.8322262551325478,0.5964120554641071,0.06279828060143189,0.7933537558921767,0.06279828060143189,-1.2364869532593843,-0.10770002139860704,1.3231682601538646,-1.0023112020703986,0.4356160170646649,0.18875209347989597,-1.2364869532593843,0.18875209347989597,-0.3248598804887178,0.3540841185619894,-0.5017540153159744,-0.3248598804887178,0.10496721166567786,-0.546410842239735,0.9860724317343753,0.27179356591045745,0.14695211780225223,-0.5912394888767456,0.909473770504105,0.27179356591045745,-0.8179346882917339,1.3231682601538646,-0.2810734678085235,2.0670777141599412,0.7150999985878068,-0.2810734678085235,-0.1940306860173823,0.3540841185619894,1.4329258820598159,-0.4572697498231123,6.354521266861696,-0.06480379588709152,-0.5017540153159744,-0.546410842239735,0.754312439228042,-0.7267490661171271,0.4356160170646649,-0.2810734678085235,0.4356160170646649
3,367
Endonuclease activity
10
46
2.525305
0.01156
O76075,Q9BSV6,Q99575,Q9ULX3,Q9BRJ7,Q8N2A8,P78345,O00584,P27695,Q96DE0
Functions
GO Molecular function
msigdb_gomf
128,334,266,72,106,142,322,18,304,28
18,1557,339,3173,587,667,128,540,1471,1833,304,1180,2446,909,2366,322,1596,1933,2869,1601,2531,1129,2687,1267,142,1708,1205,28,1798,1526,1076,266,1282,1529,106,2625,334,1147,1152,2414,72,1015,3233,891,3026,2785
4.120355977593298,-0.022088097488964575,0.909473770504105,-1.142327166182432,0.5964120554641071,0.51638636702171,1.5773671103553362,0.6361522503407359,0.020446217421404334,-0.15077592925131486,0.9860724317343753,0.18875209347989597,-0.4572697498231123,0.3540841185619894,-0.412958796825298,0.9478531474732188,-0.022088097488964575,-0.1940306860173823,-0.7267490661171271,-0.022088097488964575,-0.5017540153159744,0.23036622014532987,-0.5912394888767456,0.14695211780225223,1.5054130123499248,-0.06480379588709152,0.18875209347989597,3.535260987655072,-0.10770002139860704,0.020446217421404334,0.27179356591045745,1.099790142352336,0.14695211780225223,0.020446217421404334,1.719723884747831,-0.546410842239735,0.9478531474732188,0.23036622014532987,0.23036622014532987,-0.412958796825298,2.1351656880009666,0.31303318522898527,-1.2838097038521317,0.3949453920319386,-0.8637791771530676,-0.6362392226649662
3,367
Abnormal erythrocyte enzyme level
8
21
2.523731
0.011612
Q07020,P62899,P61313,P62847,P18077,P42766,P60891,P61353
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
134,198,74,197,165,177,24,275
1230,165,3095,177,292,3227,851,24,910,74,275,1054,680,855,197,1681,198,2264,134,924,816
0.14695211780225223,1.3964785412072227,-1.0023112020703986,1.3598932144259221,1.0241336866990407,-1.2838097038521317,0.3949453920319386,3.8312646321143324,0.3540841185619894,2.0670777141599412,1.0620389315076852,0.27179356591045745,0.51638636702171,0.3949453920319386,1.2863020037686608,-0.06480379588709152,1.2863020037686608,-0.36882191692968064,1.5414559276361184,0.3540841185619894,0.4356160170646649
3,367
Side of membrane
17
73
2.515589
0.011883
P10321,P02786,P10619,P04439,P55899,P62942,P17900,Q08431,P42892,P01889,Q6YHU6,Q9BYB4,P11279,P61353,Q14118,P46940,P35579
Localization
GO Cellular component
msigdb_gocc
213,67,68,73,43,75,46,233,16,84,279,191,90,275,327,246,245
1898,2844,1299,1558,501,2503,2154,84,67,2155,73,900,1309,1037,3340,2340,213,68,2587,90,1572,542,2798,1991,1992,46,2433,2435,2436,968,2800,846,2078,245,3066,2355,16,342,246,597,2086,43,275,855,1681,1055,75,1245,1483,2813,2744,233,798,327,1778,3102,2875,279,1948,1954,3289,2761,2626,191,1357,1079,571,2128,2054,2056,951,3088,3172
-0.1940306860173823,-0.7267490661171271,0.10496721166567786,-0.022088097488964575,0.6757140740040977,-0.5017540153159744,-0.3248598804887178,1.9985415804284918,2.202814512277326,-0.3248598804887178,2.1011771507196184,0.3540841185619894,0.10496721166567786,0.27179356591045745,-2.3646418191340213,-0.412958796825298,1.212138715175788,2.1690444425785262,-0.546410842239735,1.8948765913387664,-0.022088097488964575,0.6361522503407359,-0.6814093200124656,-0.23746346936348223,-0.23746346936348223,3.014617485988229,-0.4572697498231123,-0.4572697498231123,-0.4572697498231123,0.31303318522898527,-0.6814093200124656,0.3949453920319386,-0.2810734678085235,1.1373892537486945,-0.9559681035265681,-0.412958796825298,4.4588127644301565,0.909473770504105,1.1373892537486945,0.5964120554641071,-0.2810734678085235,3.0458947300580568,1.0620389315076852,0.3949453920319386,-0.06480379588709152,0.27179356591045745,2.0670777141599412,0.14695211780225223,0.020446217421404334,-0.6814093200124656,-0.6362392226649662,1.1748381597601374,0.4356160170646649,0.9478531474732188,-0.10770002139860704,-1.0023112020703986,-0.7267490661171271,1.0620389315076852,-0.1940306860173823,-0.1940306860173823,-1.52282763066264,-0.6362392226649662,-0.546410842239735,1.3231682601538646,0.10496721166567786,0.27179356591045745,0.6361522503407359,-0.2810734678085235,-0.23746346936348223,-0.23746346936348223,0.3540841185619894,-0.9559681035265681,-1.0954913801193207
3,367
Polysome
18
47
2.510456
0.012058
Q02543,Q9Y3U8,Q07020,P62753,P62899,Q02878,Q92616,P62701,P84098,P63173,P83881,P62266,P62888,P35580,P62917,P62424,P62910,P83731
Localization
GO Cellular component
msigdb_gocc
220,102,134,119,198,366,238,471,323,140,232,230,231,387,188,276,247,155
1660,2431,3224,1312,3092,1833,2254,2800,387,1481,1926,1242,2917,230,855,276,471,119,1681,231,198,1244,247,2264,188,140,155,232,323,1686,220,366,515,2182,134,1488,1339,2284,611,2883,3107,2826,238,3318,1213,2057,102
-0.06480379588709152,-0.4572697498231123,-1.2838097038521317,0.10496721166567786,-1.0023112020703986,-0.15077592925131486,-0.36882191692968064,-0.6814093200124656,0.8322262551325478,0.020446217421404334,-0.1940306860173823,0.14695211780225223,-0.7722577547913748,1.1748381597601374,0.3949453920319386,1.0620389315076852,0.7150999985878068,1.613148049789865,-0.06480379588709152,1.1748381597601374,1.2863020037686608,0.14695211780225223,1.1373892537486945,-0.36882191692968064,1.3231682601538646,1.5054130123499248,1.4329258820598159,1.1748381597601374,0.9478531474732188,-0.06480379588709152,1.212138715175788,0.8709321917690549,0.6757140740040977,-0.3248598804887178,1.5414559276361184,0.020446217421404334,0.10496721166567786,-0.36882191692968064,0.5964120554641071,-0.7267490661171271,-1.0023112020703986,-0.6814093200124656,1.1748381597601374,-1.7657985305992057,0.18875209347989597,-0.23746346936348223,1.7549981936289338
3,367
Predicted membrane proteins
173
473
8.287166
0
Q9UIQ6,Q8IXU6,Q99720,Q14108,P11117,Q5BJF2,O43772,P08183,Q8WTV0,Q8NCC3,O75844,Q9BQE5,O60637,P42892,Q15125,Q16850,Q5KU26,Q9NS69,O60830,O43657,O75976,Q14739,P13473,Q9UBM7,P02786,P11717,O43676,P11279,P51790,P35610,Q9NR77,P67812,Q8NBX0,Q8IV08,O94813,Q15392,Q9Y6M7,O95342,P24390,O75964,O15118,Q9H061,Q99595,Q9H490,Q5VW38,Q567V2,Q9UDX5,Q99808,Q7Z2K6,O14786,O60725,O15127,P51798,Q13423,Q96GC9,P51572,Q9Y619,Q9HD45,P01889,Q7Z7H5,P43307,Q8N511,P04439,Q969E2,P55011,Q9BTX1,Q9NZQ3,O43324,Q9BUN8,Q6ZRP7,P35613,P08195,Q92542,Q15629,P20645,O43169,P30519,Q9UM00,Q9Y266,Q9ULH0,P09601,P56589,Q14728,Q9UII4,Q9NX47,Q6UWP7,P78310,O15260,Q6ZXV5,Q99805,Q8WY22,Q9NQC3,P98194,P53634,Q9Y3E0,Q96A26,Q86UE4,O75915,O75845,P50402,Q9BXK5,Q96N66,Q99735,Q5J8M3,Q06136,Q9Y282,Q9HD20,Q9H1A4,Q9BTV4,O14828,Q969V3,Q969M3,O14975,O75165,P49257,P49755,P51648,P53985,Q15758,Q8N0U8,Q9BT22,Q14165,Q13190,P24539,Q16799,Q3SXM5,Q6NW34,Q96KA5,Q9P2W9,Q15363,O95674,Q12907,O96005,O15258,P37268,P35080,Q8IUX1,Q9Y320,Q15041,Q8TBA6,O96011,O43491,P50851,Q9BVK6,Q92896,Q96A57,Q93050,Q9Y450,Q8TEM1,Q9Y487,Q8WVX9,Q8N1F7,O15400,P12235,Q14674,Q4G176,Q07065,Q86XL3,Q96HC4,Q969N2,Q5T4S7,O75027,P11166,P13073,Q6UW02,Q5VV42,Q9BU23,Q9H3N1,Q9NX40,Q53GQ0,Q9Y639,Q15070,Q14126
Functions
Protein Atlas Protein class
protein_atlas_protein_class
2,6,7,8,9,11,12,13,14,15,19,23,21,25,26,27,28,29,32,33,34,35,36,38,41,44,46,48,49,53,57,59,60,63,68,71,72,69,74,77,75,81,90,91,88,87,100,99,98,97,102,113,115,117,118,122,127,126,120,124,121,131,128,135,138,140,142,136,149,148,145,144,158,156,152,150,153,172,184,183,173,174,177,199,198,192,188,185,205,207,206,208,204,203,226,224,222,213,212,217,244,242,243,239,234,264,262,260,258,249,285,284,266,269,272,274,275,276,310,313,316,309,306,299,340,342,343,347,351,339,323,336,324,322,332,331,371,379,369,373,355,353,362,418,412,414,413,429,409,430,410,408,383,391,403,404,401,452,456,453,448,434,437,438,493,491,501,503,506,489,512,488,487
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2,937
Endoplasmic reticulum
107
412
5.696397
0
O75503,Q99720,Q14108,Q5BJF2,O75844,Q9BQE5,Q15125,Q16850,Q14739,Q9UBM7,P07099,Q02818,O43852,P80303,Q9BTY2,P35610,Q13510,Q9UQB8,P10619,P67812,P61916,Q8IV08,Q9UMX5,Q15392,P24390,O15118,Q14257,Q32P28,P30536,Q9H490,P04062,P15289,Q7Z2K6,O60725,Q96AY3,Q96GC9,P51572,P01889,Q7Z7H5,Q01105,P43307,Q8N511,P04439,P62847,Q9BUN8,P35613,Q92542,Q15629,P30519,Q9UM00,P09601,P56589,Q9NX47,Q9H8Y8,Q86SZ2,Q6UWP7,O15260,Q6ZXV5,Q9NQC3,P98194,O15460,P53634,Q9Y3E0,Q8NFQ8,Q86UE4,O75915,O75845,P50402,Q96N66,Q99735,Q5J8M3,Q15293,O15498,O60762,Q06136,Q10471,Q9Y282,Q9HD20,Q9BTV4,P61353,O94979,Q969V3,Q969M3,O14975,P49257,P49755,P51648,Q8N0U8,Q9BT22,Q14165,Q13190,Q96HY6,Q16799,Q9P2W9,Q15363,O95674,Q12907,O15258,P37268,Q9Y320,Q15041,P50851,Q9BVK6,Q96A57,Q92890,Q9Y296,Q8TEM1
Localization
GO Cellular component
msigdb_gocc
4,7,8,11,19,23,26,27,35,38,39,40,47,50,52,53,55,56,58,59,62,63,65,71,74,75,79,80,82,91,86,95,98,102,105,118,122,120,124,123,121,131,128,139,149,145,158,156,153,172,173,174,198,197,194,192,185,205,208,204,200,203,226,223,222,213,212,217,242,243,239,237,227,228,234,235,264,262,258,252,250,285,284,266,272,274,275,313,316,309,306,346,340,351,339,323,336,322,332,379,369,362,418,414,411,425,409
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2,937
Vacuolar lumen
22
54
5.151673
0
P07602,Q14108,P11117,P06865,P38571,P15586,P50897,O14773,P04066,P06280,P13473,P16278,P54802,Q9BTY2,Q92820,Q13510,P10619,P07686,P61916,Q8IV08,P04062,P15289
Localization
GO Cellular component
msigdb_gocc
3,8,9,16,17,20,22,24,30,31,36,37,42,52,54,55,58,61,62,63,86,95
24,1443,2457,86,30,31,16,2304,1580,3,61,713,129,58,9,1457,2528,36,95,20,37,872,1466,2869,17,660,812,22,1479,1701,203,42,2478,1703,62,1151,1489,2690,55,8,669,63,1518,54,1963,686,2351,52,999,1098,181,2829,2188,1013
3.7652112572324823,-0.04871252906513763,-0.6486147893595557,1.8491689704918812,3.6169723053440874,3.6169723053440874,4.024165938684547,-0.5236513396667263,-0.10591263929674817,5.131894866624145,2.1898966319486153,0.38683824468201267,1.3941514953495935,2.3177619175977977,4.437559793002022,-0.04871252906513763,-0.7120374352425395,3.4162772870291325,1.7404982072045598,3.887244197186541,3.4162772870291325,0.2816075367943659,-0.04871252906513763,-1.6665070292939557,3.9856208887046614,0.4385452506124256,0.33452611576463864,3.8063874677803375,-0.04871252906513763,-0.16372948749216756,1.057240248022844,3.078582353860239,-0.6486147893595557,-0.16372948749216756,2.157214859958303,0.11919997011538998,-0.04871252906513763,-0.906083163548422,2.5014551385438826,4.712282471751374,0.4385452506124256,2.157214859958303,-0.04871252906513763,2.5311775269119203,-0.2812183777015856,0.4385452506124256,-0.5236513396667263,2.618889115071512,0.228081190180689,0.17394576765407171,1.1442885584140452,-1.311278575581721,-0.4011890781327106,0.228081190180689
2,937
Lysosome
25
44
5.137017
0
P07602,O75503,P10253,Q14108,P11117,Q8NCC3,P06865,P38571,P15586,P50897,O14773,P04066,P06280,P13473,P16278,P54802,P11717,P11279,Q13510,P10619,P07686,P61916,O15118,P04062,P15289
Processes and pathways
KEGG Pathways
msigdb_kegg
3,4,129,8,9,15,16,17,20,22,24,30,31,36,37,42,44,48,55,58,61,62,75,86,95
1020,1115,24,75,1443,2105,4,86,30,31,16,3,61,326,798,129,58,9,48,44,36,95,20,37,152,17,22,203,42,1149,62,1062,823,55,8,15,682,413,1408,2188,2782,1768,1014,430
0.17394576765407171,0.11919997011538998,3.7652112572324823,1.9547430671585866,-0.04871252906513763,-0.4011890781327106,4.878143286316388,1.8491689704918812,3.6169723053440874,3.6169723053440874,4.024165938684547,5.131894866624145,2.1898966319486153,0.7836800160884329,0.33452611576463864,1.3941514953495935,2.3177619175977977,4.437559793002022,2.618889115071512,2.94951498403428,3.4162772870291325,1.7404982072045598,3.887244197186541,3.4162772870291325,1.229406481355582,3.9856208887046614,3.8063874677803375,1.057240248022844,3.078582353860239,0.11919997011538998,2.157214859958303,0.17394576765407171,0.33452611576463864,2.5014551385438826,4.712282471751374,4.0999276525600274,0.4385452506124256,0.688050566378247,0.007872098580347686,-0.4011890781327106,-1.1058199287517425,-0.16372948749216756,0.228081190180689,0.688050566378247
2,937
Vacuole
42
173
4.933104
0.000001
Q8N511,Q9UIQ6,P07602,O75503,P42785,P10253,Q14108,P11117,Q5BJF2,Q8WTV0,Q8NCC3,P06865,P38571,P15586,P08195,P50897,O14773,P42892,Q92542,P20645,P04066,P06280,P13473,P16278,P54802,Q9UHG3,P11279,P51790,Q9BTY2,Q92820,Q13510,P10619,P07686,P61916,Q8IV08,O15118,P04062,P15289,Q9H0B6,Q15165,P51798,Q96GC9
Localization
GO Cellular component
msigdb_gocc
131,2,3,4,5,129,8,9,11,14,15,16,17,20,144,22,24,25,158,152,30,31,36,37,42,45,48,49,52,54,55,58,61,62,63,75,86,95,107,110,115,118
2578,1020,1115,24,75,185,383,704,1443,2105,946,570,1120,269,2831,4,1571,2114,1670,2457,86,30,641,31,16,2304,1128,1580,3,61,713,1896,144,867,2526,326,1676,129,58,9,1457,2528,48,36,95,20,37,1901,152,961,869,1232,2682,804,872,1466,656,1240,967,2869,17,2127,1363,588,5,875,25,2129,1247,660,812,362,22,1479,1480,1143,1051,49,115,1052,1701,203,2899,42,2478,1925,2543,1599,972,1703,1149,62,2773,2870,818,1927,1151,1062,887,1489,2649,401,738,823,2872,2690,55,1158,2750,8,669,1382,110,1164,11,406,63,131,1518,15,2256,14,615,551,158,54,413,2664,414,1963,1747,2818,118,498,686,2351,2857,286,500,52,999,1408,2760,107,1098,1760,502,181,778,2781,852,506,2829,2188,697,2616,2922,1420,1009,45,2782,2,1316,2368,935,1013,2672,1014,634,430,938,2711,2371
-0.7760889340064466,0.17394576765407171,0.11919997011538998,3.7652112572324823,1.9547430671585866,1.101010637080487,0.688050566378247,0.38683824468201267,-0.04871252906513763,-0.4011890781327106,0.228081190180689,0.48964847025575964,0.11919997011538998,0.8770244243066478,-1.3810415738737563,4.878143286316388,-0.10591263929674817,-0.4011890781327106,-0.16372948749216756,-0.6486147893595557,1.8491689704918812,3.6169723053440874,0.4385452506124256,3.6169723053440874,4.024165938684547,-0.5236513396667263,0.11919997011538998,-0.10591263929674817,5.131894866624145,2.1898966319486153,0.38683824468201267,-0.2812183777015856,1.2712655154383892,0.2816075367943659,-0.7120374352425395,0.7836800160884329,-0.16372948749216756,1.3941514953495935,2.3177619175977977,4.437559793002022,-0.04871252906513763,-0.7120374352425395,2.618889115071512,3.4162772870291325,1.7404982072045598,3.887244197186541,3.4162772870291325,-0.2812183777015856,1.229406481355582,0.228081190180689,0.2816075367943659,0.06384250748914849,-0.906083163548422,0.33452611576463864,0.2816075367943659,-0.04871252906513763,0.4385452506124256,0.06384250748914849,0.228081190180689,-1.6665070292939557,3.9856208887046614,-0.4011890781327106,0.007872098580347686,0.48964847025575964,4.863421508907323,0.2816075367943659,3.744431287238993,-0.4011890781327106,0.06384250748914849,0.4385452506124256,0.33452611576463864,0.7361572254974664,3.8063874677803375,-0.04871252906513763,-0.04871252906513763,0.11919997011538998,0.17394576765407171,2.618889115071512,1.473918375909616,0.17394576765407171,-0.16372948749216756,1.057240248022844,-2.0378507439803,3.078582353860239,-0.6486147893595557,-0.2812183777015856,-0.7120374352425395,-0.10591263929674817,0.228081190180689,-0.16372948749216756,0.11919997011538998,2.157214859958303,-1.1058199287517425,-1.6665070292939557,0.33452611576463864,-0.2812183777015856,0.11919997011538998,0.17394576765407171,0.2816075367943659,-0.04871252906513763,-0.8407704557687973,0.688050566378247,0.38683824468201267,0.33452611576463864,-1.6665070292939557,-0.906083163548422,2.5014551385438826,0.11919997011538998,-1.0386067543300004,4.712282471751374,0.4385452506124256,0.007872098580347686,1.5131791067781917,0.11919997011538998,4.2819961355673675,0.688050566378247,2.157214859958303,1.3941514953495935,-0.04871252906513763,4.0999276525600274,-0.4621081592112762,4.192232038011874,0.48964847025575964,0.5401492501085412,1.229406481355582,2.5311775269119203,0.688050566378247,-0.8407704557687973,0.688050566378247,-0.2812183777015856,-0.16372948749216756,-1.2421547136861633,1.473918375909616,0.5900489466309929,0.4385452506124256,-0.5236513396667263,-1.5224894117754426,0.8770244243066478,0.5900489466309929,2.618889115071512,0.228081190180689,0.007872098580347686,-1.0386067543300004,1.59049366572062,0.17394576765407171,-0.16372948749216756,0.5900489466309929,1.1442885584140452,0.38683824468201267,-1.1058199287517425,0.33452611576463864,0.5900489466309929,-1.311278575581721,-0.4011890781327106,0.4385452506124256,-0.7760889340064466,-3.510150275167924,0.007872098580347686,0.228081190180689,2.8697220435010813,-1.1058199287517425,5.198840694526526,0.06384250748914849,-0.5236513396667263,0.2816075367943659,0.228081190180689,-0.8407704557687973,0.228081190180689,0.48964847025575964,0.688050566378247,0.2816075367943659,-0.906083163548422,-0.5236513396667263
2,937
Azurophil granule
21
57
4.665505
0.000003
P07602,P10253,P42785,P06865,Q99829,P15586,Q92542,P04066,P06280,P13473,P16278,Q9H7Z7,P11279,Q9BTY2,Q92820,P10619,P07686,P61916,O15260,P53634,P15289
Localization
GO Cellular component
msigdb_gocc
3,129,5,16,286,20,158,30,31,36,37,181,48,52,54,58,61,62,185,203,95
2578,185,383,1443,1120,269,2457,30,31,16,2304,1580,3,61,129,58,2528,48,36,95,20,37,872,1466,1363,5,812,1479,1480,1143,1052,1701,203,2478,1703,62,1151,1489,401,2690,669,406,1518,2256,158,54,1963,686,2351,286,52,1098,181,2829,2188,2616,1013
-0.7760889340064466,1.101010637080487,0.688050566378247,-0.04871252906513763,0.11919997011538998,0.8770244243066478,-0.6486147893595557,3.6169723053440874,3.6169723053440874,4.024165938684547,-0.5236513396667263,-0.10591263929674817,5.131894866624145,2.1898966319486153,1.3941514953495935,2.3177619175977977,-0.7120374352425395,2.618889115071512,3.4162772870291325,1.7404982072045598,3.887244197186541,3.4162772870291325,0.2816075367943659,-0.04871252906513763,0.007872098580347686,4.863421508907323,0.33452611576463864,-0.04871252906513763,-0.04871252906513763,0.11919997011538998,0.17394576765407171,-0.16372948749216756,1.057240248022844,-0.6486147893595557,-0.16372948749216756,2.157214859958303,0.11919997011538998,-0.04871252906513763,0.688050566378247,-0.906083163548422,0.4385452506124256,0.688050566378247,-0.04871252906513763,-0.4621081592112762,1.229406481355582,2.5311775269119203,-0.2812183777015856,0.4385452506124256,-0.5236513396667263,0.8770244243066478,2.618889115071512,0.17394576765407171,1.1442885584140452,-1.311278575581721,-0.4011890781327106,-0.7760889340064466,0.228081190180689
2,937
Abnormality of the spleen
20
109
4.656174
0.000003
P07602,P10253,Q14108,P38571,P15586,P04066,Q14739,P16278,P54802,Q13510,P10619,P07686,P61916,Q15392,O95342,O15118,P04062,P51798,Q9Y285,P01889
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
3,129,8,17,20,30,35,37,42,55,58,61,62,71,69,75,86,115,119,120
1020,1563,1115,1329,75,228,707,1445,518,1890,212,1452,69,1892,2015,1221,1790,120,1894,86,30,1672,2206,1673,578,1127,3,61,1456,129,58,437,1033,2019,799,187,800,20,37,2213,2681,961,802,2807,1586,804,586,653,1136,330,1361,657,2314,17,2471,1803,1473,1590,1248,1367,725,362,1920,2037,115,1147,1053,42,2643,2396,62,1932,443,484,2140,538,1156,2691,55,1718,826,8,147,35,71,1835,449,750,2796,676,2159,1742,1289,2700,411,1294,346,1970,316,2186,2187,2188,1767,2093,119,1996,1319,1878,2711
0.17394576765407171,-0.10591263929674817,0.11919997011538998,0.007872098580347686,1.9547430671585866,0.9681807864168185,0.38683824468201267,-0.04871252906513763,0.5401492501085412,-0.2812183777015856,1.0129671489863166,-0.04871252906513763,2.057376685439682,-0.2812183777015856,-0.34089288926430916,0.06384250748914849,-0.22216432068703482,1.434245143990909,-0.2812183777015856,1.8491689704918812,3.6169723053440874,-0.16372948749216756,-0.4621081592112762,-0.16372948749216756,0.48964847025575964,0.11919997011538998,5.131894866624145,2.1898966319486153,-0.04871252906513763,1.3941514953495935,2.3177619175977977,0.6393489264185823,0.17394576765407171,-0.34089288926430916,0.33452611576463864,1.101010637080487,0.33452611576463864,3.887244197186541,3.4162772870291325,-0.4621081592112762,-0.906083163548422,0.228081190180689,0.33452611576463864,-1.2421547136861633,-0.10591263929674817,0.33452611576463864,0.48964847025575964,0.4385452506124256,0.11919997011538998,0.7836800160884329,0.007872098580347686,0.4385452506124256,-0.5236513396667263,3.9856208887046614,-0.6486147893595557,-0.22216432068703482,-0.04871252906513763,-0.10591263929674817,0.06384250748914849,0.007872098580347686,0.38683824468201267,0.7361572254974664,-0.2812183777015856,-0.34089288926430916,1.473918375909616,0.11919997011538998,0.17394576765407171,3.078582353860239,-0.8407704557687973,-0.5858198190406446,2.157214859958303,-0.2812183777015856,0.6393489264185823,0.5900489466309929,-0.4011890781327106,0.5401492501085412,0.11919997011538998,-0.906083163548422,2.5014551385438826,-0.16372948749216756,0.33452611576463864,4.712282471751374,1.2712655154383892,3.4391717680711436,2.057376685439682,-0.22216432068703482,0.6393489264185823,0.38683824468201267,-1.1736688722168886,0.4385452506124256,-0.4011890781327106,-0.16372948749216756,0.06384250748914849,-0.906083163548422,0.688050566378247,0.06384250748914849,0.7836800160884329,-0.2812183777015856,0.8306316454399105,-0.4011890781327106,-0.4011890781327106,-0.4011890781327106,-0.16372948749216756,-0.34089288926430916,1.473918375909616,-0.2812183777015856,0.06384250748914849,-0.22216432068703482,-0.906083163548422
2,937
Vacuolar membrane
22
103
4.505605
0.000007
Q8N511,Q9UIQ6,P07602,O75503,P42785,P10253,Q14108,P11117,Q8WTV0,P08195,Q92542,P42892,P13473,P11279,P51790,P10619,Q8IV08,O15118,P04062,Q9H0B6,P51798,Q96GC9
Localization
GO Cellular component
msigdb_gocc
131,2,3,4,5,129,8,9,14,144,158,25,36,48,49,58,63,75,86,107,115,118
1020,1115,75,185,383,2105,946,1120,269,4,1571,2114,1670,86,641,2304,3,1896,144,867,2526,326,129,58,9,1457,48,36,152,961,869,1232,656,1240,967,2127,1363,588,5,25,1247,1143,1051,49,115,1052,2899,1925,2543,972,1149,2773,2870,818,1927,1062,2649,401,738,823,2750,8,1382,1164,406,63,131,2256,14,615,551,158,413,1747,2818,118,498,2857,286,500,1408,2760,107,1760,502,778,2781,852,2188,697,2616,2922,1009,2782,2,1316,2368,935,2672,1014,634,430,2711
0.17394576765407171,0.11919997011538998,1.9547430671585866,1.101010637080487,0.688050566378247,-0.4011890781327106,0.228081190180689,0.11919997011538998,0.8770244243066478,4.878143286316388,-0.10591263929674817,-0.4011890781327106,-0.16372948749216756,1.8491689704918812,0.4385452506124256,-0.5236513396667263,5.131894866624145,-0.2812183777015856,1.2712655154383892,0.2816075367943659,-0.7120374352425395,0.7836800160884329,1.3941514953495935,2.3177619175977977,4.437559793002022,-0.04871252906513763,2.618889115071512,3.4162772870291325,1.229406481355582,0.228081190180689,0.2816075367943659,0.06384250748914849,0.4385452506124256,0.06384250748914849,0.228081190180689,-0.4011890781327106,0.007872098580347686,0.48964847025575964,4.863421508907323,3.744431287238993,0.06384250748914849,0.11919997011538998,0.17394576765407171,2.618889115071512,1.473918375909616,0.17394576765407171,-2.0378507439803,-0.2812183777015856,-0.7120374352425395,0.228081190180689,0.11919997011538998,-1.1058199287517425,-1.6665070292939557,0.33452611576463864,-0.2812183777015856,0.17394576765407171,-0.8407704557687973,0.688050566378247,0.38683824468201267,0.33452611576463864,-1.0386067543300004,4.712282471751374,0.007872098580347686,0.11919997011538998,0.688050566378247,2.157214859958303,1.3941514953495935,-0.4621081592112762,4.192232038011874,0.48964847025575964,0.5401492501085412,1.229406481355582,0.688050566378247,-0.16372948749216756,-1.2421547136861633,1.473918375909616,0.5900489466309929,-1.5224894117754426,0.8770244243066478,0.5900489466309929,0.007872098580347686,-1.0386067543300004,1.59049366572062,-0.16372948749216756,0.5900489466309929,0.38683824468201267,-1.1058199287517425,0.33452611576463864,-0.4011890781327106,0.4385452506124256,-0.7760889340064466,-3.510150275167924,0.228081190180689,-1.1058199287517425,5.198840694526526,0.06384250748914849,-0.5236513396667263,0.2816075367943659,-0.8407704557687973,0.228081190180689,0.48964847025575964,0.688050566378247,-0.906083163548422
2,937
Lysosomal lumen
20
29
4.458399
0.000008
P07602,Q14108,P11117,P06865,P38571,P15586,P50897,O14773,P04066,P06280,P13473,P16278,P54802,Q13510,P10619,P07686,P61916,Q8IV08,P04062,P15289
Localization
GO Cellular component
msigdb_gocc
3,8,9,16,17,20,22,24,30,31,36,37,42,55,58,61,62,63,86,95
24,1443,86,30,31,16,3,61,713,129,58,9,1457,36,95,20,37,2869,17,660,22,42,62,55,8,63,1518,999,2188
3.7652112572324823,-0.04871252906513763,1.8491689704918812,3.6169723053440874,3.6169723053440874,4.024165938684547,5.131894866624145,2.1898966319486153,0.38683824468201267,1.3941514953495935,2.3177619175977977,4.437559793002022,-0.04871252906513763,3.4162772870291325,1.7404982072045598,3.887244197186541,3.4162772870291325,-1.6665070292939557,3.9856208887046614,0.4385452506124256,3.8063874677803375,3.078582353860239,2.157214859958303,2.5014551385438826,4.712282471751374,2.157214859958303,-0.04871252906513763,0.228081190180689,-0.4011890781327106
2,937
Splenomegaly
17
80
4.329644
0.000015
P07602,Q14739,P16278,Q15392,P10253,Q14108,O95342,P54802,O15118,P38571,P51798,P15586,Q13510,P61916,P04062,P01889,P04066
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
3,35,37,71,129,8,69,42,75,17,115,20,55,62,86,120,30
1020,1563,1115,1329,75,228,707,1445,518,1890,69,1892,1221,1790,120,1894,86,30,1672,2206,1673,578,1127,3,129,437,1033,2019,799,187,800,20,37,2213,2681,961,802,2807,804,586,653,1136,330,1361,657,17,1590,1367,725,362,2037,115,1147,1053,42,2396,62,1932,484,538,55,1718,8,147,35,71,1835,449,750,2796,2159,2700,411,1294,346,316,2186,2187,2188,2093
0.17394576765407171,-0.10591263929674817,0.11919997011538998,0.007872098580347686,1.9547430671585866,0.9681807864168185,0.38683824468201267,-0.04871252906513763,0.5401492501085412,-0.2812183777015856,2.057376685439682,-0.2812183777015856,0.06384250748914849,-0.22216432068703482,1.434245143990909,-0.2812183777015856,1.8491689704918812,3.6169723053440874,-0.16372948749216756,-0.4621081592112762,-0.16372948749216756,0.48964847025575964,0.11919997011538998,5.131894866624145,1.3941514953495935,0.6393489264185823,0.17394576765407171,-0.34089288926430916,0.33452611576463864,1.101010637080487,0.33452611576463864,3.887244197186541,3.4162772870291325,-0.4621081592112762,-0.906083163548422,0.228081190180689,0.33452611576463864,-1.2421547136861633,0.33452611576463864,0.48964847025575964,0.4385452506124256,0.11919997011538998,0.7836800160884329,0.007872098580347686,0.4385452506124256,3.9856208887046614,-0.10591263929674817,0.007872098580347686,0.38683824468201267,0.7361572254974664,-0.34089288926430916,1.473918375909616,0.11919997011538998,0.17394576765407171,3.078582353860239,-0.5858198190406446,2.157214859958303,-0.2812183777015856,0.5900489466309929,0.5401492501085412,2.5014551385438826,-0.16372948749216756,4.712282471751374,1.2712655154383892,3.4391717680711436,2.057376685439682,-0.22216432068703482,0.6393489264185823,0.38683824468201267,-1.1736688722168886,-0.4011890781327106,-0.906083163548422,0.688050566378247,0.06384250748914849,0.7836800160884329,0.8306316454399105,-0.4011890781327106,-0.4011890781327106,-0.4011890781327106,-0.34089288926430916
2,937
Potential drug targets
80
460
4.324838
0.000015
P07602,Q14108,P11117,O15164,O43772,P06865,P38571,O75844,P15586,P50897,O14773,P42892,Q15125,P04066,P06280,Q14739,P13473,P16278,Q9UBM7,P07099,P54802,Q13510,P10619,P07686,P61916,Q8IV08,Q15392,O95342,O15118,Q32P28,Q9H061,Q4J6C6,P04062,P15289,Q01433,Q96AY3,P51798,P51572,Q9Y619,Q8N511,P04439,Q14376,O60826,Q9H4A3,Q9UM00,Q16851,Q14004,P40855,Q9ULH0,P09601,P56589,Q96L58,P12955,Q6ZXV5,O15460,P53634,Q6NUK1,O75845,Q96N66,Q9Y4U1,P41227,O60762,Q06136,Q10471,O94979,P49257,P51648,P53985,Q9BT22,Q9H2D1,O60493,P05165,P50570,P19404,P33991,P37268,Q8IUX1,Q96BN8,Q9Y320,Q9Y5K6
Functions
Protein Atlas Protein class
protein_atlas_protein_class
3,8,9,10,12,16,17,19,20,22,24,25,26,30,31,35,36,37,38,39,42,55,58,61,62,63,71,69,75,80,81,85,86,95,103,105,115,122,127,131,128,147,143,160,172,168,166,164,183,173,174,196,187,205,200,203,220,212,242,248,231,228,234,235,250,272,275,276,316,317,293,298,303,328,330,332,371,374,379,382
1324,1562,1326,1563,1778,1882,1327,1437,24,942,1329,75,10,1438,1022,2198,1439,1440,200,1441,2378,12,2713,1661,2451,1444,2379,293,1886,1118,2110,1887,228,143,434,1336,1446,1663,2627,1664,1448,1783,1784,1570,1890,19,212,2832,950,1573,2897,250,1668,1669,69,388,1892,1343,1123,2013,1027,796,2015,2456,2457,2458,2302,1222,2303,1790,86,30,1672,1576,1346,2739,128,2206,298,2208,1673,31,712,578,16,39,1674,1128,3,61,642,1675,2017,2117,643,2118,2883,1581,173,1676,2305,58,2586,9,437,1033,2019,1679,1584,799,390,580,187,581,438,36,1681,800,1351,1459,1585,95,20,37,1352,2213,1132,1133,1684,646,2681,328,1794,2460,1687,1905,1688,584,2634,1232,2462,1586,1233,2463,2531,2464,2214,2309,2466,962,963,2026,1463,965,1236,586,653,2216,1038,1356,1357,1137,2469,1468,330,874,2589,1043,1801,477,2741,967,1361,527,1362,1469,1471,332,657,2314,17,1472,1363,2885,164,1912,1244,231,529,1693,1803,2771,25,2473,1590,660,591,1475,724,2391,1248,2034,272,2317,2886,1695,1917,2537,2318,1807,2744,1808,2538,661,2475,725,303,1478,1698,22,1480,1051,2887,1920,122,275,2808,2037,115,2640,1812,1368,1922,1923,1813,203,2899,2924,276,971,2225,1814,1053,42,1054,1815,2478,2540,1148,2643,2226,1817,174,1598,2396,2745,1599,594,2822,1256,1483,62,2772,2773,2232,2041,1604,2480,1062,103,1376,1931,1261,1932,443,2140,234,2046,444,1712,235,823,538,2141,1264,485,1494,55,1718,1719,2750,826,166,8,1162,147,2240,35,897,1612,2051,1832,2824,26,1833,71,2054,672,2333,168,2599,80,746,404,85,2334,2487,1386,2335,544,1507,491,1510,220,1949,2339,1169,608,2410,205,752,1734,2059,2728,2812,1172,2813,371,63,2921,1280,408,911,131,914,2062,2161,2063,1176,2499,1082,373,2257,1850,2164,1742,2258,915,410,2262,916,761,763,1181,1294,105,374,2268,1747,2933,2607,1748,196,1968,242,498,415,997,2270,685,2425,1530,2609,1753,1091,2733,2502,2759,2564,2272,1974,316,1978,2827,2073,2566,2569,81,556,317,2735,846,1639,160,2431,1302,1763,693,1003,2781,1193,1004,2762,2508,1986,2669,2509,2182,851,1544,929,1006,695,1007,2088,460,696,1546,1420,2285,38,631,2189,2904,1423,2845,2287,1767,2783,183,172,1873,1647,508,2766,2093,2094,1875,379,1431,511,248,1016,1017,382,1556,1878,2516,2295,127
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2,937
Receptor
16
33
4.256082
0.000021
Q14739,P78310,O14786,Q99720,Q14108,P02786,P24390,P11717,Q8WTV0,O15118,P11279,P35613,Q9NS69,Q9Y2W1,Q5KU26,P20645
Functions
Protein Atlas Molecular function
protein_atlas_molecular_function
35,188,97,7,8,41,74,44,14,75,48,145,29,265,28,152
1325,97,75,861,41,1345,797,952,1455,1456,1678,48,44,1682,152,74,807,145,188,484,2482,8,35,310,28,14,1293,2070,7,29,1428,265,1320
0.007872098580347686,1.7035577277228184,1.9547430671585866,0.2816075367943659,3.1288971739076072,0.007872098580347686,0.33452611576463864,0.228081190180689,-0.04871252906513763,-0.04871252906513763,-0.16372948749216756,2.618889115071512,2.94951498403428,-0.16372948749216756,1.229406481355582,1.9892736116862897,0.33452611576463864,1.2712655154383892,1.101010637080487,0.5900489466309929,-0.6486147893595557,4.712282471751374,3.4391717680711436,0.8306316454399105,3.681306413452911,4.192232038011874,0.06384250748914849,-0.34089288926430916,4.758390219688548,3.681306413452911,0.007872098580347686,0.9228702829555585,0.06384250748914849
2,937
Steroid metabolic process
14
62
4.205657
0.000026
Q14739,Q9UBM7,Q15392,O95342,Q8WTV0,O15118,P38571,P30536,Q9BQE5,P35610,Q13510,Q15125,Q16850,P61916
Processes and pathways
GO Biological process
msigdb_gobp
35,38,71,69,14,75,17,82,23,53,55,26,27,62
266,75,212,1573,69,1343,2457,86,1895,357,799,521,1230,1352,2023,2634,2462,2466,653,82,53,332,2869,17,2472,2391,2744,1249,2037,1701,62,1375,1709,1932,821,1936,55,827,2146,35,1382,26,1833,71,1615,1067,2054,27,489,406,14,1394,416,2501,23,2275,1002,38,377,1425,2763,1873
0.8770244243066478,1.9547430671585866,1.0129671489863166,-0.10591263929674817,2.057376685439682,0.007872098580347686,-0.6486147893595557,1.8491689704918812,-0.2812183777015856,0.7361572254974664,0.33452611576463864,0.5401492501085412,0.06384250748914849,0.007872098580347686,-0.34089288926430916,-0.8407704557687973,-0.6486147893595557,-0.6486147893595557,0.4385452506124256,1.8846964555914798,2.589890921013961,0.7836800160884329,-1.6665070292939557,3.9856208887046614,-0.6486147893595557,-0.5858198190406446,-1.0386067543300004,0.06384250748914849,-0.34089288926430916,-0.16372948749216756,2.157214859958303,0.007872098580347686,-0.16372948749216756,-0.2812183777015856,0.33452611576463864,-0.2812183777015856,2.5014551385438826,0.33452611576463864,-0.4011890781327106,3.4391717680711436,0.007872098580347686,3.7024803541208557,-0.22216432068703482,2.057376685439682,-0.10591263929674817,0.17394576765407171,-0.34089288926430916,3.7024803541208557,0.5900489466309929,0.688050566378247,4.192232038011874,0.007872098580347686,0.688050566378247,-0.6486147893595557,3.8063874677803375,-0.4621081592112762,0.228081190180689,3.4162772870291325,0.7361572254974664,0.007872098580347686,-1.0386067543300004,-0.22216432068703482
2,937
Circulatory system process
17
60
4.057313
0.00005
Q9HB40,Q9UIQ6,P10253,P53985,P42785,P78310,O94813,Q99808,Q07157,P55011,P02786,Q96AC1,P08183,O75844,Q9H4A3,P09601,P42892
Processes and pathways
GO Biological process
msigdb_gobp
0,2,129,276,5,188,68,99,255,138,41,241,13,19,160,173,25
1326,1563,1437,1118,1784,19,2452,1450,68,2457,41,1346,2207,1895,13,173,129,437,2210,2884,2911,957,1132,1686,1905,806,807,1473,588,5,25,1248,1915,1249,1145,276,138,1599,1256,1704,188,2593,2401,366,255,2793,1715,1498,487,895,1163,310,2339,1621,241,99,160,0,2187,2
0.007872098580347686,-0.10591263929674817,-0.04871252906513763,0.11919997011538998,-0.22216432068703482,3.926946339483657,-0.6486147893595557,-0.04871252906513763,2.057376685439682,-0.6486147893595557,3.1288971739076072,0.007872098580347686,-0.4621081592112762,-0.2812183777015856,4.192232038011874,1.1442885584140452,1.3941514953495935,0.6393489264185823,-0.4621081592112762,-1.8873708060077286,-2.425443155290095,0.228081190180689,0.11919997011538998,-0.16372948749216756,-0.2812183777015856,0.33452611576463864,0.33452611576463864,-0.04871252906513763,0.48964847025575964,4.863421508907323,3.744431287238993,0.06384250748914849,-0.2812183777015856,0.06384250748914849,0.11919997011538998,0.8770244243066478,1.3126701679029467,-0.10591263929674817,0.06384250748914849,-0.16372948749216756,1.101010637080487,-0.7760889340064466,-0.5858198190406446,0.7361572254974664,0.9228702829555585,-1.1736688722168886,-0.16372948749216756,-0.04871252906513763,0.5900489466309929,0.2816075367943659,0.11919997011538998,0.8306316454399105,-0.5236513396667263,-0.10591263929674817,0.9681807864168185,1.7035577277228184,1.229406481355582,5.893957451831641,-0.4011890781327106,5.198840694526526
2,937
Lipid localization
14
66
4.008415
0.000061
P07602,Q99720,Q14108,O95342,O43772,P08183,Q8WTV0,O15118,P30536,Q9BQE5,P35610,P04062,P07686,P61916
Processes and pathways
GO Biological process
msigdb_gobp
3,7,8,69,12,13,14,75,82,23,53,86,61,62
565,292,266,75,185,12,862,1218,69,2203,323,796,2302,86,2680,2304,3,61,1675,13,437,800,2023,2634,718,653,82,2469,2861,53,480,877,62,886,1375,2140,1936,8,2146,1382,2334,406,2339,2063,14,118,416,7,23,1533,1535,2074,1000,2569,318,1300,852,2188,2616,377,933,2090,1109,2368,2371,2623
0.48964847025575964,0.8306316454399105,0.8770244243066478,1.9547430671585866,1.101010637080487,4.2103839880354075,0.2816075367943659,0.06384250748914849,2.057376685439682,-0.4621081592112762,0.7836800160884329,0.33452611576463864,-0.5236513396667263,1.8491689704918812,-0.906083163548422,-0.5236513396667263,5.131894866624145,2.1898966319486153,-0.16372948749216756,4.192232038011874,0.6393489264185823,0.33452611576463864,-0.34089288926430916,-0.8407704557687973,0.38683824468201267,0.4385452506124256,1.8846964555914798,-0.6486147893595557,-1.5941764518204824,2.589890921013961,0.5900489466309929,0.2816075367943659,2.157214859958303,0.2816075367943659,0.007872098580347686,-0.4011890781327106,-0.2812183777015856,4.712282471751374,-0.4011890781327106,0.007872098580347686,-0.5236513396667263,0.688050566378247,-0.5236513396667263,-0.34089288926430916,4.192232038011874,1.473918375909616,0.688050566378247,4.758390219688548,3.8063874677803375,-0.04871252906513763,-0.04871252906513763,-0.34089288926430916,0.228081190180689,-0.7120374352425395,0.8306316454399105,0.06384250748914849,0.33452611576463864,-0.4011890781327106,-0.7760889340064466,0.7361572254974664,0.2816075367943659,-0.34089288926430916,0.17394576765407171,-0.5236513396667263,-0.5236513396667263,-0.7760889340064466
2,937
Intrinsic component of plasma membrane
32
60
4.00798
0.000061
Q9UIQ6,P04439,P55011,Q8WTV0,P35613,O60637,Q92542,P20645,O43657,P12235,P53985,Q15758,P02786,P11717,P11279,P51790,Q7L5Y9,O43813,P78310,P11166,Q99805,O15118,Q9BTU6,Q12907,O96005,Q99808,O14786,Q9Y639,O15498,P51572,Q04721,P01889
Localization
GO Cellular component
msigdb_gocc
2,128,138,14,145,21,158,152,33,391,276,310,41,44,48,49,450,66,188,437,207,75,500,336,324,99,97,512,227,122,484,120
565,1325,97,2003,75,227,33,66,21,795,324,120,41,128,1895,1223,797,2923,437,48,44,391,957,1686,152,805,807,2470,145,1361,122,49,276,1369,138,188,1604,1261,484,1378,336,2482,1725,310,450,547,911,14,158,2733,207,99,500,2508,2185,2,1767,935,2919,512
0.48964847025575964,0.007872098580347686,1.7035577277228184,-0.34089288926430916,1.9547430671585866,0.9681807864168185,3.4619133058097864,2.090959820673029,3.8063874677803375,0.33452611576463864,0.7836800160884329,1.434245143990909,3.1288971739076072,1.3941514953495935,-0.2812183777015856,0.06384250748914849,0.33452611576463864,-3.598238387349531,0.6393489264185823,2.618889115071512,2.94951498403428,0.688050566378247,0.228081190180689,-0.16372948749216756,1.229406481355582,0.33452611576463864,0.33452611576463864,-0.6486147893595557,1.2712655154383892,0.007872098580347686,1.434245143990909,2.618889115071512,0.8770244243066478,0.007872098580347686,1.3126701679029467,1.101010637080487,-0.10591263929674817,0.06384250748914849,0.5900489466309929,0.007872098580347686,0.7836800160884329,-0.6486147893595557,-0.16372948749216756,0.8306316454399105,0.6393489264185823,0.5401492501085412,0.2816075367943659,4.192232038011874,1.229406481355582,-0.9720282133639213,1.057240248022844,1.7035577277228184,0.5900489466309929,-0.6486147893595557,-0.4011890781327106,5.198840694526526,-0.16372948749216756,0.2816075367943659,-2.9956170913795845,0.5900489466309929
2,937
Membrane lipid metabolic process
15
33
3.955722
0.000076
P07602,P16278,Q99735,Q99805,Q8NCC3,P06865,O60762,P50897,Q13510,Q9H490,P04062,Q8NBX0,P07686,P04066,P06280
Processes and pathways
GO Biological process
msigdb_gobp
3,37,243,207,15,16,228,22,55,91,86,60,61,30,31
1022,2198,789,228,1343,86,30,31,16,3,61,37,2023,1237,22,234,1936,55,2487,679,60,15,761,453,2067,243,207,91,2088,696,2188,630,2616
0.17394576765407171,-0.4621081592112762,0.33452611576463864,0.9681807864168185,0.007872098580347686,1.8491689704918812,3.6169723053440874,3.6169723053440874,4.024165938684547,5.131894866624145,2.1898966319486153,3.4162772870291325,-0.34089288926430916,0.06384250748914849,3.8063874677803375,0.9681807864168185,-0.2812183777015856,2.5014551385438826,-0.6486147893595557,0.4385452506124256,2.222287625540094,4.0999276525600274,0.38683824468201267,0.6393489264185823,-0.34089288926430916,0.9681807864168185,1.057240248022844,1.8491689704918812,-0.34089288926430916,0.4385452506124256,-0.4011890781327106,0.48964847025575964,-0.7760889340064466
2,937
Sterol metabolic process
11
35
3.892071
0.000099
Q14739,Q9UBM7,Q15392,Q8WTV0,O15118,P38571,Q9BQE5,P35610,Q15125,Q16850,P61916
Processes and pathways
GO Biological process
msigdb_gobp
35,38,71,14,75,17,23,53,26,27,62
75,212,1573,2457,86,799,521,1352,2462,53,332,17,2472,2391,2744,1701,62,1375,1709,1932,1936,827,2146,35,1382,26,1833,71,2054,27,14,23,38,377,2763
1.9547430671585866,1.0129671489863166,-0.10591263929674817,-0.6486147893595557,1.8491689704918812,0.33452611576463864,0.5401492501085412,0.007872098580347686,-0.6486147893595557,2.589890921013961,0.7836800160884329,3.9856208887046614,-0.6486147893595557,-0.5858198190406446,-1.0386067543300004,-0.16372948749216756,2.157214859958303,0.007872098580347686,-0.16372948749216756,-0.2812183777015856,-0.2812183777015856,0.33452611576463864,-0.4011890781327106,3.4391717680711436,0.007872098580347686,3.7024803541208557,-0.22216432068703482,2.057376685439682,-0.34089288926430916,3.7024803541208557,4.192232038011874,3.8063874677803375,3.4162772870291325,0.7361572254974664,-1.0386067543300004
2,937
Abnormality of femur morphology
12
63
3.862852
0.000112
P07602,Q14739,P16278,P55011,Q96AY3,Q32P28,O75844,P51798,Q9Y619,P04062,P04066,P06280
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
3,35,37,138,105,80,19,115,127,86,30,31
1324,1563,1778,942,1332,1118,1663,2009,2112,2299,19,1123,575,796,1894,86,30,2206,31,3,37,1352,1905,964,872,2314,2315,1590,2536,1591,115,2640,1813,138,594,35,983,897,2406,80,449,343,2251,344,1735,1742,1746,1294,105,346,196,1091,1403,1538,1986,851,1766,2188,1108,2709,430,1878,127
0.007872098580347686,-0.10591263929674817,-0.22216432068703482,0.228081190180689,0.007872098580347686,0.11919997011538998,-0.16372948749216756,-0.34089288926430916,-0.4011890781327106,-0.5236513396667263,3.926946339483657,0.11919997011538998,0.48964847025575964,0.33452611576463864,-0.2812183777015856,1.8491689704918812,3.6169723053440874,-0.4621081592112762,3.6169723053440874,5.131894866624145,3.4162772870291325,0.007872098580347686,-0.2812183777015856,0.228081190180689,0.2816075367943659,-0.5236513396667263,-0.5236513396667263,-0.10591263929674817,-0.7120374352425395,-0.10591263929674817,1.473918375909616,-0.8407704557687973,-0.22216432068703482,1.3126701679029467,0.48964847025575964,3.4391717680711436,0.228081190180689,0.2816075367943659,-0.5858198190406446,1.919885894471246,0.6393489264185823,0.7836800160884329,-0.4621081592112762,0.7836800160884329,-0.16372948749216756,-0.16372948749216756,-0.16372948749216756,0.06384250748914849,1.628562285011634,0.7836800160884329,1.101010637080487,0.17394576765407171,0.007872098580347686,-0.04871252906513763,-0.2812183777015856,0.33452611576463864,-0.16372948749216756,-0.4011890781327106,0.17394576765407171,-0.906083163548422,0.688050566378247,-0.22216432068703482,1.434245143990909
2,937
Exopeptidase activity
14
32
3.82235
0.000132
Q9HB40,Q9H3G5,Q9UIQ6,O75976,Q7Z2K6,P42785,P12955,P02786,Q969V3,P53634,O75844,Q92820,O14773,P10619
Functions
GO Molecular function
msigdb_gomf
0,1,2,34,98,5,187,41,285,203,19,54,24,58
24,19,34,41,1583,58,187,1796,1136,1361,5,2476,203,663,2325,2237,98,2415,1514,54,285,2817,496,286,1,1983,0,2762,1642,627,2187,2
3.7652112572324823,3.926946339483657,3.4391717680711436,3.1288971739076072,-0.10591263929674817,2.3177619175977977,1.101010637080487,-0.22216432068703482,0.11919997011538998,0.007872098580347686,4.863421508907323,-0.6486147893595557,1.057240248022844,0.4385452506124256,-0.5236513396667263,-0.4621081592112762,1.7035577277228184,-0.5858198190406446,-0.04871252906513763,2.5311775269119203,0.8770244243066478,-1.2421547136861633,0.5900489466309929,0.8770244243066478,5.830215713580066,-0.2812183777015856,5.893957451831641,-1.0386067543300004,-0.10591263929674817,0.48964847025575964,-0.4011890781327106,5.198840694526526
2,937
Intrinsic component of organelle membrane
51
109
3.810992
0.000138
Q9BTV4,Q15286,Q15388,P04439,Q86UP2,Q8NE86,Q6UXV4,Q9NZ01,Q9BUN8,Q6ZRP7,Q9HC21,O75844,Q8WVX9,P42892,Q15125,Q15629,O14975,O60830,Q9UM00,Q14739,P13473,P12235,Q9UBM7,Q86XL3,P56589,O96008,Q8TB61,Q5SNT2,Q6P4A7,Q969N2,Q16799,Q9P035,O43505,O15118,Q9NQC3,P98194,Q99595,Q9H490,O15258,Q10471,O95563,O95070,O96011,A0FGR8,Q15070,Q5J8M3,Q15041,P51572,Q9Y282,P01889,Q8TCT9
Localization
GO Cellular component
msigdb_gocc
258,256,541,128,547,549,281,696,149,148,693,19,410,25,26,156,266,32,172,35,36,391,38,452,174,297,614,606,608,453,340,630,76,75,208,204,90,91,322,235,574,572,355,565,488,239,369,122,264,120,680
565,2518,943,266,75,322,789,1212,76,862,706,32,2009,19,2832,2382,572,1668,1343,574,297,355,120,128,2923,391,36,1686,716,804,805,1909,2315,25,877,1051,122,174,2227,1483,204,1604,235,1608,1157,2238,35,2852,369,488,26,256,541,156,1505,340,830,2487,239,606,987,608,281,148,547,452,1078,2604,2416,2498,914,549,614,680,410,761,453,1294,2561,2067,90,2564,1533,258,149,1535,1407,845,91,923,1302,693,2572,208,2184,1106,696,630,698,38,1871,2859,172,264,1996,2802,1016,1113,2371
0.48964847025575964,-0.7120374352425395,0.228081190180689,0.8770244243066478,1.9547430671585866,0.7836800160884329,0.33452611576463864,0.06384250748914849,1.9547430671585866,0.2816075367943659,0.38683824468201267,3.59525158154659,-0.34089288926430916,3.926946339483657,-1.3810415738737563,-0.5858198190406446,0.48964847025575964,-0.16372948749216756,0.007872098580347686,0.48964847025575964,0.8306316454399105,0.7361572254974664,1.434245143990909,1.3941514953495935,-3.598238387349531,0.688050566378247,3.4162772870291325,-0.16372948749216756,0.38683824468201267,0.33452611576463864,0.33452611576463864,-0.2812183777015856,-0.5236513396667263,3.744431287238993,0.2816075367943659,0.17394576765407171,1.434245143990909,1.1442885584140452,-0.4621081592112762,-0.04871252906513763,1.057240248022844,-0.10591263929674817,0.9681807864168185,-0.10591263929674817,0.11919997011538998,-0.4621081592112762,3.4391717680711436,-1.5224894117754426,0.7361572254974664,0.5900489466309929,3.7024803541208557,0.9228702829555585,0.5401492501085412,1.229406481355582,-0.04871252906513763,0.7836800160884329,0.33452611576463864,-0.6486147893595557,0.9681807864168185,0.48964847025575964,0.228081190180689,0.48964847025575964,0.8770244243066478,1.2712655154383892,0.5401492501085412,0.6393489264185823,0.17394576765407171,-0.7760889340064466,-0.5858198190406446,-0.6486147893595557,0.2816075367943659,0.5401492501085412,0.48964847025575964,0.4385452506124256,0.688050566378247,0.38683824468201267,0.6393489264185823,0.06384250748914849,-0.7120374352425395,-0.34089288926430916,1.8491689704918812,-0.7120374352425395,-0.04871252906513763,0.9228702829555585,1.2712655154383892,-0.04871252906513763,0.007872098580347686,0.33452611576463864,1.8491689704918812,0.2816075367943659,0.06384250748914849,0.4385452506124256,-0.7120374352425395,1.057240248022844,-0.4011890781327106,0.17394576765407171,0.4385452506124256,0.48964847025575964,0.4385452506124256,3.4162772870291325,-0.22216432068703482,-1.5224894117754426,1.1870839548927827,0.9228702829555585,-0.2812183777015856,-1.1736688722168886,0.228081190180689,0.17394576765407171,-0.5236513396667263
2,937
Molecular transducer activity
11
28
3.80962
0.000139
O43813,O14786,Q99720,Q14108,P11717,Q8WTV0,O15118,Q9BUN8,P30536,Q15629,Q5KU26
Functions
GO Molecular function
msigdb_gomf
66,97,7,8,44,14,75,149,82,156,28
97,75,861,66,1345,797,44,152,82,2471,1047,1367,1152,484,1378,2482,8,156,310,542,28,14,1293,7,149,2185,698,1423
1.7035577277228184,1.9547430671585866,0.2816075367943659,2.090959820673029,0.007872098580347686,0.33452611576463864,2.94951498403428,1.229406481355582,1.8846964555914798,-0.6486147893595557,0.17394576765407171,0.007872098580347686,0.11919997011538998,0.5900489466309929,0.007872098580347686,-0.6486147893595557,4.712282471751374,1.229406481355582,0.8306316454399105,0.5401492501085412,3.681306413452911,4.192232038011874,0.06384250748914849,4.758390219688548,1.2712655154383892,-0.4011890781327106,0.4385452506124256,0.007872098580347686
2,937
Transporter activity
48
147
3.790051
0.000151
Q96SU4,Q8IXU6,Q93050,P55011,O43772,P08183,Q8WTV0,Q99829,Q9Y487,P08195,O14975,Q9NS69,O60830,P49755,Q9UM00,P53985,P06576,Q15758,P12235,P21796,Q9H2D1,O43676,P51790,P24539,Q14728,O96008,O75947,P61916,Q14847,O75027,P11166,Q9Y6M7,O95342,O75964,O15118,P98194,P30536,Q99595,Q6NUK1,P19404,P04062,P56385,Q99808,P51798,Q13423,Q96GC9,Q9Y619,Q9HD20
Functions
GO Molecular function
msigdb_gomf
416,6,413,138,12,13,14,286,430,144,266,29,32,274,172,276,389,310,391,394,317,46,49,299,177,297,296,62,447,434,437,72,69,77,75,204,82,90,220,328,86,334,99,115,117,118,127,262
2518,2100,1433,1437,943,266,75,861,46,1443,12,862,32,434,1336,1446,709,1664,1570,296,77,2382,1788,2805,1452,2454,69,574,1789,297,2458,86,1895,1223,389,2304,1896,13,144,1581,2119,579,437,391,1458,438,1900,957,328,1686,1687,961,869,394,2023,299,2215,653,2216,82,807,2029,1692,967,2869,2127,1365,724,2743,480,274,2538,49,115,593,2641,1812,1922,276,138,2038,334,1149,1483,62,204,886,1604,2480,1261,1933,117,540,177,447,1382,541,310,671,1728,2334,2727,220,2339,608,752,6,2498,2160,758,549,614,14,1293,413,118,2561,685,416,1753,90,2733,99,286,1974,688,2074,1000,317,923,693,262,29,2918,1200,1422,1423,2782,1767,172,2708,2292,430,1776,127,72,1019
-0.7120374352425395,-0.4011890781327106,-0.04871252906513763,-0.04871252906513763,0.228081190180689,0.8770244243066478,1.9547430671585866,0.2816075367943659,2.8427159818750036,-0.04871252906513763,4.2103839880354075,0.2816075367943659,3.59525158154659,0.6393489264185823,0.007872098580347686,-0.04871252906513763,0.38683824468201267,-0.16372948749216756,-0.10591263929674817,0.8306316454399105,1.9547430671585866,-0.5858198190406446,-0.22216432068703482,-1.2421547136861633,-0.04871252906513763,-0.6486147893595557,2.057376685439682,0.48964847025575964,-0.22216432068703482,0.8306316454399105,-0.6486147893595557,1.8491689704918812,-0.2812183777015856,0.06384250748914849,0.688050566378247,-0.5236513396667263,-0.2812183777015856,4.192232038011874,1.2712655154383892,-0.10591263929674817,-0.4011890781327106,0.48964847025575964,0.6393489264185823,0.688050566378247,-0.04871252906513763,0.6393489264185823,-0.2812183777015856,0.228081190180689,0.7836800160884329,-0.16372948749216756,-0.16372948749216756,0.228081190180689,0.2816075367943659,0.688050566378247,-0.34089288926430916,0.8306316454399105,-0.4621081592112762,0.4385452506124256,-0.4621081592112762,1.8846964555914798,0.33452611576463864,-0.34089288926430916,-0.16372948749216756,0.228081190180689,-1.6665070292939557,-0.4011890781327106,0.007872098580347686,0.38683824468201267,-1.0386067543300004,0.5900489466309929,0.8770244243066478,-0.7120374352425395,2.618889115071512,1.473918375909616,0.48964847025575964,-0.8407704557687973,-0.22216432068703482,-0.2812183777015856,0.8770244243066478,1.3126701679029467,-0.34089288926430916,0.7836800160884329,0.11919997011538998,-0.04871252906513763,2.157214859958303,1.057240248022844,0.2816075367943659,-0.10591263929674817,-0.6486147893595557,0.06384250748914849,-0.2812183777015856,1.473918375909616,0.5401492501085412,1.1442885584140452,0.6393489264185823,0.007872098580347686,0.5401492501085412,0.8306316454399105,0.4385452506124256,-0.16372948749216756,-0.5236513396667263,-0.9720282133639213,1.0129671489863166,-0.5236513396667263,0.48964847025575964,0.38683824468201267,4.8486302687541105,-0.6486147893595557,-0.4011890781327106,0.38683824468201267,0.5401492501085412,0.48964847025575964,4.192232038011874,0.06384250748914849,0.688050566378247,1.473918375909616,-0.7120374352425395,0.4385452506124256,0.688050566378247,-0.16372948749216756,1.8491689704918812,-0.9720282133639213,1.7035577277228184,0.8770244243066478,-0.2812183777015856,0.4385452506124256,-0.34089288926430916,0.228081190180689,0.8306316454399105,0.2816075367943659,0.4385452506124256,0.9228702829555585,3.681306413452911,-2.9956170913795845,0.11919997011538998,0.007872098580347686,0.007872098580347686,-1.1058199287517425,-0.16372948749216756,1.1870839548927827,-0.906083163548422,-0.4621081592112762,0.688050566378247,-0.16372948749216756,1.434245143990909,2.057376685439682,0.228081190180689
2,937
Abnormality of the lymphatic system
43
135
3.780263
0.000157
P07602,P10253,Q92890,Q14108,Q14376,P38571,P15586,Q13428,Q10713,P04066,O75533,Q14739,P16278,P54802,Q9BT22,Q13510,Q6NUQ1,P10619,P07686,P61916,Q96HY6,P12955,Q15392,P11166,O95342,Q04446,O15118,O15460,Q01844,Q13426,P04062,P48735,P33991,Q99496,O75845,Q96BN8,O15160,P51798,O60762,Q9Y285,Q04721,P01889,P50851
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
3,129,411,8,147,17,20,540,538,30,518,35,37,42,316,55,449,58,61,62,346,187,71,437,69,443,75,200,442,337,86,216,330,96,212,374,467,115,228,119,484,120,362
1020,1563,1115,1329,75,467,200,228,707,1445,518,1890,212,948,1452,69,1892,2015,1221,1790,120,1894,86,30,1672,2206,1673,578,1127,3,61,1456,129,58,714,437,1033,2019,799,1034,187,581,800,20,37,2213,2681,961,523,802,2807,1586,804,586,653,1136,2469,330,2589,1142,1361,657,2314,17,2471,1803,1473,1590,1248,216,1367,725,362,1920,2037,115,1147,2225,1053,42,1054,2643,2396,1599,62,442,1932,443,484,2140,538,739,1156,337,540,2691,55,1718,826,8,147,35,1723,71,1835,603,449,750,2058,2753,2796,676,2159,1742,1289,2700,411,1294,374,346,1970,96,316,1540,2186,2914,2187,2188,1767,2093,119,1996,1319,1878,2711
0.17394576765407171,-0.10591263929674817,0.11919997011538998,0.007872098580347686,1.9547430671585866,0.5900489466309929,1.057240248022844,0.9681807864168185,0.38683824468201267,-0.04871252906513763,0.5401492501085412,-0.2812183777015856,1.0129671489863166,0.228081190180689,-0.04871252906513763,2.057376685439682,-0.2812183777015856,-0.34089288926430916,0.06384250748914849,-0.22216432068703482,1.434245143990909,-0.2812183777015856,1.8491689704918812,3.6169723053440874,-0.16372948749216756,-0.4621081592112762,-0.16372948749216756,0.48964847025575964,0.11919997011538998,5.131894866624145,2.1898966319486153,-0.04871252906513763,1.3941514953495935,2.3177619175977977,0.38683824468201267,0.6393489264185823,0.17394576765407171,-0.34089288926430916,0.33452611576463864,0.17394576765407171,1.101010637080487,0.48964847025575964,0.33452611576463864,3.887244197186541,3.4162772870291325,-0.4621081592112762,-0.906083163548422,0.228081190180689,0.5401492501085412,0.33452611576463864,-1.2421547136861633,-0.10591263929674817,0.33452611576463864,0.48964847025575964,0.4385452506124256,0.11919997011538998,-0.6486147893595557,0.7836800160884329,-0.7760889340064466,0.11919997011538998,0.007872098580347686,0.4385452506124256,-0.5236513396667263,3.9856208887046614,-0.6486147893595557,-0.22216432068703482,-0.04871252906513763,-0.10591263929674817,0.06384250748914849,1.0129671489863166,0.007872098580347686,0.38683824468201267,0.7361572254974664,-0.2812183777015856,-0.34089288926430916,1.473918375909616,0.11919997011538998,-0.4621081592112762,0.17394576765407171,3.078582353860239,0.17394576765407171,-0.8407704557687973,-0.5858198190406446,-0.10591263929674817,2.157214859958303,0.6393489264185823,-0.2812183777015856,0.6393489264185823,0.5900489466309929,-0.4011890781327106,0.5401492501085412,0.38683824468201267,0.11919997011538998,0.7836800160884329,0.5401492501085412,-0.906083163548422,2.5014551385438826,-0.16372948749216756,0.33452611576463864,4.712282471751374,1.2712655154383892,3.4391717680711436,-0.16372948749216756,2.057376685439682,-0.22216432068703482,0.48964847025575964,0.6393489264185823,0.38683824468201267,-0.34089288926430916,-1.0386067543300004,-1.1736688722168886,0.4385452506124256,-0.4011890781327106,-0.16372948749216756,0.06384250748914849,-0.906083163548422,0.688050566378247,0.06384250748914849,0.7361572254974664,0.7836800160884329,-0.2812183777015856,1.7404982072045598,0.8306316454399105,-0.04871252906513763,-0.4011890781327106,-2.425443155290095,-0.4011890781327106,-0.4011890781327106,-0.16372948749216756,-0.34089288926430916,1.473918375909616,-0.2812183777015856,0.06384250748914849,-0.22216432068703482,-0.906083163548422
2,937
Mental deterioration
17
93
3.751009
0.000176
P07602,O75503,P16278,P20700,O60934,Q14108,Q9Y4U1,P54802,O15118,P06865,Q9BQE5,P50897,Q13510,P04062,P07686,P61916,P15289
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
3,4,37,133,186,8,248,42,75,16,23,22,55,86,61,62,95
1326,75,1443,706,1661,186,269,1446,4,2832,1668,1343,297,2458,1790,86,1576,1347,16,3,61,2118,2527,2305,714,1900,95,37,1035,1684,133,1688,802,1462,1235,2534,1690,359,967,2127,1245,875,1589,1695,22,1920,1249,971,42,1815,2478,62,1057,1062,443,736,2649,1490,538,2546,55,8,1065,2051,2335,987,1949,2410,1276,2921,913,410,1746,763,1853,498,997,2609,2173,2501,23,2901,246,1417,2866,2188,1010,2189,2845,1873,2622,430,248
0.007872098580347686,1.9547430671585866,-0.04871252906513763,0.38683824468201267,-0.16372948749216756,1.101010637080487,0.8770244243066478,-0.04871252906513763,4.878143286316388,-1.3810415738737563,-0.16372948749216756,0.007872098580347686,0.8306316454399105,-0.6486147893595557,-0.22216432068703482,1.8491689704918812,-0.10591263929674817,0.007872098580347686,4.024165938684547,5.131894866624145,2.1898966319486153,-0.4011890781327106,-0.7120374352425395,-0.5236513396667263,0.38683824468201267,-0.2812183777015856,1.7404982072045598,3.4162772870291325,0.17394576765407171,-0.16372948749216756,1.3536292924938709,-0.16372948749216756,0.33452611576463864,-0.04871252906513763,0.06384250748914849,-0.7120374352425395,-0.16372948749216756,0.7361572254974664,0.228081190180689,-0.4011890781327106,0.06384250748914849,0.2816075367943659,-0.10591263929674817,-0.16372948749216756,3.8063874677803375,-0.2812183777015856,0.06384250748914849,0.228081190180689,3.078582353860239,-0.22216432068703482,-0.6486147893595557,2.157214859958303,0.17394576765407171,0.17394576765407171,0.6393489264185823,0.38683824468201267,-0.8407704557687973,-0.04871252906513763,0.5401492501085412,-0.7120374352425395,2.5014551385438826,4.712282471751374,0.17394576765407171,-0.34089288926430916,-0.5236513396667263,0.228081190180689,-0.2812183777015856,-0.5858198190406446,0.06384250748914849,-3.510150275167924,0.2816075367943659,0.688050566378247,-0.16372948749216756,0.38683824468201267,-0.22216432068703482,0.5900489466309929,0.228081190180689,-0.7760889340064466,-0.4011890781327106,-0.6486147893595557,3.8063874677803375,-2.0378507439803,0.9681807864168185,0.007872098580347686,-1.5941764518204824,-0.4011890781327106,0.228081190180689,-0.4011890781327106,-1.451444818165324,-0.22216432068703482,-0.7760889340064466,0.688050566378247,0.9681807864168185
2,937
Organelle subcompartment
104
319
3.734197
0.000188
Q99720,Q14108,Q5BJF2,O75844,Q9BQE5,Q15125,Q16850,Q14739,Q9UBM7,P07099,P11717,O43852,P35610,P67812,Q8IV08,Q15392,P24390,Q4J6C6,Q9H490,P04062,Q7Z2K6,O60725,O15127,Q96GC9,P51572,P01889,Q7Z7H5,P43307,Q8N511,P04439,Q969E2,Q9BUN8,P35613,Q15629,P20645,P30519,Q9UM00,P09601,Q9NX47,Q9H8Y8,Q96L58,Q86SZ2,Q6UWP7,O15260,Q9NQC3,P98194,Q8NFQ8,Q86UE4,O75915,O75845,P50402,Q96N66,Q99735,Q5J8M3,O60762,Q06136,Q10471,Q9Y282,Q9HD20,P61353,O94979,O14828,Q969V3,Q92538,Q969M3,O14975,O75122,P49257,P49755,P51648,Q8N0U8,Q9BT22,Q14165,Q13190,P50570,Q96HY6,Q16799,Q9P2W9,Q15363,O95674,Q12907,P09496,P37268,Q9Y320,Q15041,Q8TBA6,Q9BVK6,Q96A57,Q92890,Q9Y296,Q8TEM1,Q9Y678,P61006,O43795,Q5VYK3,Q07065,Q86XL3,Q6NUQ1,Q969N2,O94874,Q9BTU6,Q5VV42,Q9BU23,Q9H3N1
Localization
GO Cellular component
msigdb_gocc
7,8,11,19,23,26,27,35,38,39,44,47,53,59,63,71,74,85,91,86,98,102,113,118,122,120,124,121,131,128,135,149,145,156,152,153,172,173,198,197,196,194,192,185,208,204,223,222,213,212,217,242,243,239,228,234,235,264,262,252,250,249,285,283,284,266,268,272,274,275,313,316,309,306,303,346,340,351,339,323,336,326,332,379,369,373,418,414,411,425,409,432,395,385,405,401,452,449,453,436,500,491,501,503
565,465,1559,1325,1326,1563,1778,2102,2447,249,1209,860,266,2579,113,185,1022,2198,2581,789,1212,2105,385,47,2379,1118,102,228,1335,268,517,1024,1219,2010,19,212,213,2832,436,1786,1573,2524,250,572,1342,1669,1343,951,2203,323,795,796,2457,1790,120,86,128,519,641,952,39,1455,2526,326,798,173,2119,2923,44,1229,1352,957,2632,1231,152,1905,2023,1232,74,1354,804,805,1796,1356,1909,153,806,1138,2861,1141,53,145,332,2869,1363,1243,588,121,1247,591,1591,2391,2034,480,272,274,217,303,1919,1810,122,275,1052,2132,532,2134,1924,1147,2478,1925,2227,2541,2720,2543,1599,395,729,1373,972,252,1256,1483,883,1601,1705,2809,2877,2400,59,1603,204,1062,735,1931,484,234,401,1263,2721,235,823,538,1264,336,1608,306,1719,1498,2653,826,8,309,2238,2146,35,982,1382,1830,2597,2852,369,2775,1613,26,1725,339,1164,71,745,156,2054,1271,340,27,2599,85,489,11,239,986,2337,491,405,2491,1511,449,1274,2339,904,192,98,124,194,222,547,452,1078,63,2496,2921,313,911,2498,131,679,913,914,1516,2159,2256,223,2907,2163,614,373,2257,1850,2164,680,409,1288,551,1178,283,1083,837,761,411,135,284,453,285,1294,414,2423,1963,118,838,346,996,196,242,2067,685,2173,7,243,2734,2759,23,2900,2072,1533,316,500,501,149,1535,1406,418,999,1408,1000,1638,2428,503,91,2430,197,2434,2572,262,1411,208,2280,927,198,2088,696,2187,630,2616,698,351,1311,38,1423,2763,933,1768,1770,172,935,1012,264,425,379,2098,2576,2293,2710,2802,1320,2001,2786,432,2371,2623,1558
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2,937
Secondary alcohol metabolic process
10
39
3.716431
0.000202
Q14739,Q9UBM7,Q15392,Q8WTV0,O15118,Q9BQE5,P35610,Q15125,Q16850,P61916
Processes and pathways
GO Biological process
msigdb_gobp
35,38,71,14,75,23,53,26,27,62
75,386,212,948,1573,2457,86,799,521,1352,2462,53,332,2472,2391,216,2744,2591,878,1701,62,1375,1709,1932,1936,827,2146,35,1382,26,1833,71,2054,27,14,2502,23,38,377
1.9547430671585866,0.688050566378247,1.0129671489863166,0.228081190180689,-0.10591263929674817,-0.6486147893595557,1.8491689704918812,0.33452611576463864,0.5401492501085412,0.007872098580347686,-0.6486147893595557,2.589890921013961,0.7836800160884329,-0.6486147893595557,-0.5858198190406446,1.0129671489863166,-1.0386067543300004,-0.7760889340064466,0.2816075367943659,-0.16372948749216756,2.157214859958303,0.007872098580347686,-0.16372948749216756,-0.2812183777015856,-0.2812183777015856,0.33452611576463864,-0.4011890781327106,3.4391717680711436,0.007872098580347686,3.7024803541208557,-0.22216432068703482,2.057376685439682,-0.34089288926430916,3.7024803541208557,4.192232038011874,-0.6486147893595557,3.8063874677803375,3.4162772870291325,0.7361572254974664
2,937
Azurophil granule lumen
11
35
3.652616
0.00026
P16278,Q9H7Z7,P15586,Q9BTY2,Q92820,P15289,P61916,P10619,P07686,P04066,P06280
Localization
GO Cellular component
msigdb_gocc
37,181,20,52,54,95,62,58,61,30,31
1443,2457,30,31,2304,1580,61,58,2528,95,20,37,872,1466,812,1479,1701,203,2478,1703,62,1151,1489,2690,669,1518,54,1963,686,2351,52,1098,181,2829,1013
-0.04871252906513763,-0.6486147893595557,3.6169723053440874,3.6169723053440874,-0.5236513396667263,-0.10591263929674817,2.1898966319486153,2.3177619175977977,-0.7120374352425395,1.7404982072045598,3.887244197186541,3.4162772870291325,0.2816075367943659,-0.04871252906513763,0.33452611576463864,-0.04871252906513763,-0.16372948749216756,1.057240248022844,-0.6486147893595557,-0.16372948749216756,2.157214859958303,0.11919997011538998,-0.04871252906513763,-0.906083163548422,0.4385452506124256,-0.04871252906513763,2.5311775269119203,-0.2812183777015856,0.4385452506124256,-0.5236513396667263,2.618889115071512,0.17394576765407171,1.1442885584140452,-1.311278575581721,0.228081190180689
2,937
Golgi membrane
40
112
3.611498
0.000304
Q9BVK6,P04439,Q92896,Q14108,Q92538,Q9Y296,Q6ZRP7,P35613,Q9Y678,P49257,P49755,Q9UM00,P11717,Q9H7Z7,P51790,Q13190,Q9H8Y8,Q96L58,Q8IV08,P50570,Q16799,Q15392,O15260,O95342,Q7LGA3,P24390,Q8N6T3,O43505,P98194,Q9P2W9,Q15363,Q9Y3E0,Q12907,O15258,Q10471,Q8TBA6,O15498,P51572,Q9Y282,P01889
Localization
GO Cellular component
msigdb_gocc
418,128,412,8,283,425,148,145,432,272,274,172,44,181,49,306,197,196,63,303,340,71,185,69,344,74,345,76,204,351,339,226,336,322,235,373,227,122,264,120
2518,2102,1115,2579,322,185,227,76,2377,2105,1335,1219,572,1342,69,794,1790,120,128,2526,2119,2923,437,44,2023,74,1141,145,2898,1243,588,1591,480,272,274,303,122,49,2132,532,2134,1924,2541,2543,1599,395,1373,972,1601,1059,204,484,1263,2721,235,823,538,336,306,8,982,1723,1725,339,1164,71,745,1271,340,148,344,1172,1736,63,2498,345,2161,2256,614,373,1741,1288,283,412,196,685,1535,418,2798,1408,1002,2430,181,197,2781,927,2088,2616,351,1311,1107,1551,1770,172,264,425,2442,2875,634,2293,226,432
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2,937
Alpha/Beta hydrolase fold [IPR029058]
8
22
3.599682
0.000319
Q9HB40,Q9H3G5,P42785,P07099,Q8NCC3,P38571,P50897,P10619
Sequence
InterPro Superfamily
interpro_homologous_superfamily
0,1,5,39,15,17,22,58
1447,39,58,2716,582,17,5,2130,1367,22,85,904,2415,911,15,1528,1,1300,0,2183,2670,2577
-0.04871252906513763,3.3700219703880934,2.3177619175977977,-0.9720282133639213,0.48964847025575964,3.9856208887046614,4.863421508907323,-0.4011890781327106,0.007872098580347686,3.8063874677803375,1.8846964555914798,0.2816075367943659,-0.5858198190406446,0.2816075367943659,4.0999276525600274,-0.04871252906513763,5.830215713580066,0.06384250748914849,5.893957451831641,-0.4011890781327106,-0.8407704557687973,-0.7120374352425395
2,937
Vascular process in circulatory system
10
27
3.587254
0.000334
Q9HB40,Q99808,P53985,O94813,Q96AC1,Q07157,P55011,P02786,P08183,P42892
Processes and pathways
GO Biological process
msigdb_gobp
0,99,276,68,241,255,138,41,13,25
1563,1437,1118,1450,68,41,1346,13,437,1686,807,25,1248,1915,1145,276,138,1256,366,255,1715,1163,310,2339,241,99,0
-0.10591263929674817,-0.04871252906513763,0.11919997011538998,-0.04871252906513763,2.057376685439682,3.1288971739076072,0.007872098580347686,4.192232038011874,0.6393489264185823,-0.16372948749216756,0.33452611576463864,3.744431287238993,0.06384250748914849,-0.2812183777015856,0.11919997011538998,0.8770244243066478,1.3126701679029467,0.06384250748914849,0.7361572254974664,0.9228702829555585,-0.16372948749216756,0.11919997011538998,0.8306316454399105,-0.5236513396667263,0.9681807864168185,1.7035577277228184,5.893957451831641
2,937
Transport
97
424
3.580772
0.000343
Q8IXU6,Q99720,O43772,P08183,Q9BQE5,Q9NS69,O60830,P11717,O43676,P51790,P61916,Q9Y6M7,O95342,A0AVF1,P24390,O75964,O15118,Q99595,Q8N4H5,O14949,Q99808,Q16881,O15127,P51798,P51572,Q9BZI7,Q9Y619,Q7Z7H5,Q969E2,P55011,Q9BTX1,Q9BUN8,P08195,O60826,Q15629,P20645,O43169,Q9UM00,Q14728,P98194,Q9Y3E0,Q6NUK1,O43592,O15498,Q9Y282,Q9UN86,Q9HD20,Q15286,O94979,O14828,Q92538,Q969M3,O15397,O75165,P49257,P49755,P53985,Q15758,Q7Z3U7,Q9H2D1,Q9H4M9,Q9NVZ3,Q13190,P24539,O60493,O96008,O75947,Q8N6T3,Q9UNH7,Q9P2W9,Q15363,Q12907,P19404,P56385,O43491,Q9BVK6,Q96SU4,Q93050,Q9Y296,Q8TEM1,Q9Y487,Q9Y678,Q8N1F7,P61006,P06576,P12235,P21796,P82979,Q96A65,Q6NUQ1,Q9Y5L4,Q14847,O75027,P11166,Q96QK1,Q6DKK2,Q9H269
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
6,7,12,13,23,29,32,44,46,49,62,72,69,73,74,77,75,90,92,94,99,111,113,115,122,125,127,124,135,138,140,149,144,143,156,152,150,172,177,204,226,220,211,227,264,263,262,256,250,249,283,284,267,269,272,274,276,310,311,317,318,320,306,299,293,297,296,345,352,351,339,336,328,334,353,418,416,413,425,409,430,432,408,395,389,391,394,400,455,449,463,447,434,437,498,492,502
73,565,1559,1114,2578,2768,1020,2100,941,2296,1779,1433,2519,567,2102,1115,859,249,943,94,1656,2579,75,113,267,227,150,704,2581,1442,353,211,1213,2377,46,1443,705,2105,12,862,2108,293,1218,1023,570,1335,143,32,2582,434,2200,269,1336,1446,1024,709,1219,2009,2831,1664,1784,1570,296,77,865,2114,250,572,1788,2805,1342,1452,2454,69,2383,471,951,574,794,1670,795,1789,297,2458,2302,1895,1223,389,13,144,1581,2527,2119,437,1033,44,391,1458,580,2212,1351,957,959,328,1686,960,2022,716,152,961,869,394,1688,2023,2634,2462,1462,1233,718,74,299,2215,653,2216,807,2534,2469,2029,1140,1141,477,2898,1692,967,1471,2849,2127,1472,659,1245,810,1365,1050,1247,724,2743,1591,480,272,2316,274,1696,1808,2538,877,1143,1051,1919,122,49,115,1052,593,2132,1921,1812,1922,2134,1924,2899,276,1147,1369,1055,138,814,2478,1925,2038,334,2541,1598,2720,2543,395,1373,972,1149,1483,62,1601,2790,1059,1374,818,1927,2399,2400,2648,400,885,1061,204,886,1604,1375,1261,1490,1711,2234,2721,1491,2774,823,2141,336,1608,306,1155,978,1157,1158,1609,2144,2404,1065,669,177,447,1382,1830,256,339,541,745,156,310,984,1505,1270,671,1728,111,2600,2334,673,986,544,2337,492,2727,220,449,2339,608,2154,752,2552,2342,1074,2156,311,124,909,2778,1279,6,1513,408,92,2498,345,2063,758,549,2499,2555,1958,1177,614,2164,834,409,1393,2557,915,1522,615,1288,283,682,916,2347,1525,413,135,284,2664,455,995,1747,2818,2731,838,2169,2561,1088,1751,498,685,416,998,1753,90,7,2857,99,2174,2564,23,1974,1976,1533,688,140,149,1535,418,1635,2827,2798,2074,1408,1862,1000,125,1189,1537,1760,502,317,2429,503,846,2430,318,2079,692,923,2278,693,2572,262,2781,1411,1866,2669,29,2086,928,852,1005,320,2087,2866,1196,2188,697,2918,2922,698,351,1311,562,1312,2286,1200,1422,1423,2782,2438,2364,933,1201,1767,1551,1768,1109,1426,1770,172,1316,702,2368,263,352,935,2290,2292,264,425,1014,2576,2293,226,1111,430,2785,938,2515,2000,1776,2905,463,1878,2711,2001,127,432,2623,1557,564,72,1019
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2,937
Endocytosis
20
94
3.578319
0.000346
Q14108,Q9NZQ3,Q8WTV0,Q08380,P50897,Q5KU26,O75165,P20645,P02786,P11717,Q9H4M9,Q9NVZ3,P51790,P50570,O15260,Q8N6T3,O15118,P09496,Q5VW38,Q9Y5K6
Processes and pathways
GO Biological process
msigdb_gobp
8,142,14,18,22,28,269,152,41,44,318,320,49,303,185,345,75,326,88,382
565,1207,1326,1563,2373,75,185,2105,570,269,1571,2114,1670,41,797,2304,326,798,44,439,2631,2632,2022,716,152,1586,871,805,872,655,1140,587,659,303,22,1143,1051,49,1052,2899,1599,2229,1059,1708,818,1603,2480,1062,1489,1490,18,1497,1158,2750,2653,8,1827,367,1267,1725,2055,2334,986,28,88,1169,1624,345,2160,2889,14,1747,998,2173,2174,1531,1638,1538,318,320,506,142,1009,2782,1551,1554,1770,1316,702,2708,1202,1014,382,2001
0.48964847025575964,0.06384250748914849,0.007872098580347686,-0.10591263929674817,-0.5858198190406446,1.9547430671585866,1.101010637080487,-0.4011890781327106,0.48964847025575964,0.8770244243066478,-0.10591263929674817,-0.4011890781327106,-0.16372948749216756,3.1288971739076072,0.33452611576463864,-0.5236513396667263,0.7836800160884329,0.33452611576463864,2.94951498403428,0.6393489264185823,-0.8407704557687973,-0.8407704557687973,-0.34089288926430916,0.38683824468201267,1.229406481355582,-0.10591263929674817,0.2816075367943659,0.33452611576463864,0.2816075367943659,0.4385452506124256,0.11919997011538998,0.48964847025575964,0.4385452506124256,0.8306316454399105,3.8063874677803375,0.11919997011538998,0.17394576765407171,2.618889115071512,0.17394576765407171,-2.0378507439803,-0.10591263929674817,-0.4621081592112762,0.17394576765407171,-0.16372948749216756,0.33452611576463864,-0.10591263929674817,-0.6486147893595557,0.17394576765407171,-0.04871252906513763,-0.04871252906513763,3.9661781891098036,-0.04871252906513763,0.11919997011538998,-1.0386067543300004,-0.8407704557687973,4.712282471751374,-0.22216432068703482,0.7361572254974664,0.06384250748914849,-0.16372948749216756,-0.34089288926430916,-0.5236513396667263,0.228081190180689,3.681306413452911,1.8491689704918812,0.11919997011538998,-0.10591263929674817,0.7836800160884329,-0.4011890781327106,-1.8873708060077286,4.192232038011874,-0.16372948749216756,0.228081190180689,-0.4011890781327106,-0.4011890781327106,-0.04871252906513763,-0.10591263929674817,-0.04871252906513763,0.8306316454399105,0.8306316454399105,0.5900489466309929,1.3126701679029467,0.228081190180689,-1.1058199287517425,-0.04871252906513763,-0.04871252906513763,-0.16372948749216756,0.06384250748914849,0.4385452506124256,-0.906083163548422,0.11919997011538998,0.228081190180689,0.7361572254974664,-0.2812183777015856
2,937
Abnormal circulating lipid concentration
22
71
3.565902
0.000363
Q9BTV4,Q8N511,P07602,O43772,P38571,O75844,Q15125,P06280,P49257,Q14739,Q9UBM7,P40855,P56589,P61916,Q15392,Q13426,P37268,O75845,P50402,Q9Y4U1,Q9Y285,Q10471
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
258,131,3,12,17,19,26,31,272,35,38,164,174,62,71,337,332,212,217,248,119,235
942,705,12,2009,1783,19,212,1343,355,1894,31,712,3,1676,1584,2463,718,586,1038,2469,2684,1801,2741,332,17,164,1244,875,2222,272,2744,217,877,1920,2037,1053,2540,174,1598,62,1150,1262,235,445,337,980,35,1503,26,71,2054,1068,2844,131,1519,1178,453,2856,258,2277,2360,2188,38,2287,1767,119,938,2802,248,2905,2623
0.228081190180689,0.38683824468201267,4.2103839880354075,-0.34089288926430916,-0.22216432068703482,3.926946339483657,1.0129671489863166,0.007872098580347686,0.7361572254974664,-0.2812183777015856,3.6169723053440874,0.38683824468201267,5.131894866624145,-0.16372948749216756,-0.10591263929674817,-0.6486147893595557,0.38683824468201267,0.48964847025575964,0.17394576765407171,-0.6486147893595557,-0.906083163548422,-0.22216432068703482,-1.0386067543300004,0.7836800160884329,3.9856208887046614,1.1870839548927827,0.06384250748914849,0.2816075367943659,-0.4621081592112762,0.8770244243066478,-1.0386067543300004,1.0129671489863166,0.2816075367943659,-0.2812183777015856,-0.34089288926430916,0.17394576765407171,-0.7120374352425395,1.1442885584140452,-0.10591263929674817,2.157214859958303,0.11919997011538998,0.06384250748914849,0.9681807864168185,0.6393489264185823,0.7836800160884329,0.228081190180689,3.4391717680711436,-0.04871252906513763,3.7024803541208557,2.057376685439682,-0.34089288926430916,0.17394576765407171,-1.451444818165324,1.3941514953495935,-0.04871252906513763,0.11919997011538998,0.6393489264185823,-1.5224894117754426,0.9228702829555585,-0.4621081592112762,-0.5236513396667263,-0.4011890781327106,3.4162772870291325,-0.4621081592112762,-0.16372948749216756,1.473918375909616,0.2816075367943659,-1.1736688722168886,0.9681807864168185,-2.1909305126679395,-0.7760889340064466
2,937
Endoplasmic reticulum golgi intermediate compartment
20
40
3.554192
0.000379
Q9BVK6,Q8N511,Q92538,Q9Y678,P49257,P49755,Q02818,P80303,Q13190,O15260,P24390,Q15363,P53634,Q12907,O15258,O15498,Q96GC9,P51572,Q9Y282,Q7Z7H5
Localization
GO Cellular component
msigdb_gocc
418,131,283,432,272,274,40,50,306,185,74,339,203,336,322,227,118,122,264,124
322,185,227,1219,572,1674,954,74,804,655,272,274,970,122,2134,203,50,40,2721,336,306,982,1613,339,405,124,1279,131,283,2265,118,2072,418,628,1311,1107,264,2293,432,636
0.7836800160884329,1.101010637080487,0.9681807864168185,0.06384250748914849,0.48964847025575964,-0.16372948749216756,0.228081190180689,1.9892736116862897,0.33452611576463864,0.4385452506124256,0.8770244243066478,0.8770244243066478,0.228081190180689,1.434245143990909,-0.4011890781327106,1.057240248022844,2.618889115071512,3.17849140779286,-0.9720282133639213,0.7836800160884329,0.8306316454399105,0.228081190180689,-0.10591263929674817,0.7836800160884329,0.688050566378247,1.434245143990909,0.06384250748914849,1.3941514953495935,0.8770244243066478,-0.4621081592112762,1.473918375909616,-0.34089288926430916,0.688050566378247,0.48964847025575964,0.06384250748914849,0.17394576765407171,0.9228702829555585,-0.4621081592112762,0.688050566378247,0.48964847025575964
2,937
Recurrent respiratory infections
25
111
3.514416
0.000441
P07602,P10253,Q00577,P20700,Q9Y487,P15586,O60826,P26038,P04066,P16278,Q16851,P02786,P54802,P09601,Q13510,P12955,O60934,Q6NW34,O15460,P53634,P04062,P33991,P51798,P01889,P50851
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
3,129,254,133,430,20,143,270,30,37,168,41,42,173,55,187,186,343,200,203,86,330,115,120,362
1020,1021,1115,942,2003,200,143,707,186,1445,1787,1452,388,1892,1027,2015,1221,1790,120,41,86,30,1127,1454,3,173,2459,129,2019,1898,187,581,800,1585,20,37,1684,1794,133,2461,1905,651,270,1463,872,1136,330,2684,2471,529,1473,2536,1248,362,726,1249,115,1922,1813,203,2225,42,1054,2745,594,2647,1150,2232,254,1931,484,2748,1607,1156,55,1718,1162,1503,1163,1944,1165,2693,168,1948,1510,343,2699,2753,676,1285,993,1181,1852,1399,1749,1859,2428,1864,1982,1539,2085,2186,2188,2189,933,2287,1314,2672,430,938,2802
0.17394576765407171,0.17394576765407171,0.11919997011538998,0.228081190180689,-0.34089288926430916,1.057240248022844,1.2712655154383892,0.38683824468201267,1.101010637080487,-0.04871252906513763,-0.22216432068703482,-0.04871252906513763,0.688050566378247,-0.2812183777015856,0.17394576765407171,-0.34089288926430916,0.06384250748914849,-0.22216432068703482,1.434245143990909,3.1288971739076072,1.8491689704918812,3.6169723053440874,0.11919997011538998,-0.04871252906513763,5.131894866624145,1.1442885584140452,-0.6486147893595557,1.3941514953495935,-0.34089288926430916,-0.2812183777015856,1.101010637080487,0.48964847025575964,0.33452611576463864,-0.10591263929674817,3.887244197186541,3.4162772870291325,-0.16372948749216756,-0.22216432068703482,1.3536292924938709,-0.6486147893595557,-0.2812183777015856,0.4385452506124256,0.8770244243066478,-0.04871252906513763,0.2816075367943659,0.11919997011538998,0.7836800160884329,-0.906083163548422,-0.6486147893595557,0.5401492501085412,-0.04871252906513763,-0.7120374352425395,0.06384250748914849,0.7361572254974664,0.38683824468201267,0.06384250748914849,1.473918375909616,-0.2812183777015856,-0.22216432068703482,1.057240248022844,-0.4621081592112762,3.078582353860239,0.17394576765407171,-1.0386067543300004,0.48964847025575964,-0.8407704557687973,0.11919997011538998,-0.4621081592112762,0.9228702829555585,-0.2812183777015856,0.5900489466309929,-1.0386067543300004,-0.10591263929674817,0.11919997011538998,2.5014551385438826,-0.16372948749216756,0.11919997011538998,-0.04871252906513763,0.11919997011538998,-0.2812183777015856,0.11919997011538998,-0.906083163548422,1.1870839548927827,-0.2812183777015856,-0.04871252906513763,0.7836800160884329,-0.906083163548422,-1.0386067543300004,0.4385452506124256,0.06384250748914849,0.228081190180689,0.11919997011538998,-0.22216432068703482,0.007872098580347686,-0.16372948749216756,-0.22216432068703482,-0.5858198190406446,-0.22216432068703482,-0.2812183777015856,-0.04871252906513763,-0.34089288926430916,-0.4011890781327106,-0.4011890781327106,-0.4011890781327106,0.2816075367943659,-0.4621081592112762,0.06384250748914849,-0.8407704557687973,0.688050566378247,0.2816075367943659,-1.1736688722168886
2,937
Lipid binding
20
117
3.474073
0.000513
Q15286,P07602,Q14108,Q92538,Q8WTV0,Q8NCC3,Q9BQE5,P50897,O14773,P11717,P35610,P56589,P61916,O15118,P30536,Q9H490,P04062,P46940,Q96AC1,Q9NQZ5
Functions
GO Molecular function
msigdb_gomf
256,3,8,283,14,15,23,22,24,44,53,174,62,75,82,91,86,215,241,246
565,1325,1207,1326,1563,2447,24,75,861,2376,1439,789,385,1661,293,570,1120,1573,2114,86,2680,1345,1895,2304,3,2385,1896,954,2586,1457,1033,44,2210,1231,523,394,2023,2634,2312,586,2532,1798,82,331,53,1471,2869,1365,2390,215,480,22,1480,2133,1596,532,2478,2642,174,2320,62,2399,886,1375,596,1153,445,1497,742,1158,8,1382,1723,1832,256,2601,753,1624,1954,1513,15,2555,14,283,761,241,1747,1749,416,998,2070,286,1531,1858,23,1533,1407,2074,1000,91,2430,246,2359,2188,1009,1768,2090,1554,702,2708,352,1428,634,787,2919,2711,2001
0.48964847025575964,0.007872098580347686,0.06384250748914849,0.007872098580347686,-0.10591263929674817,-0.6486147893595557,3.7652112572324823,1.9547430671585866,0.2816075367943659,-0.5858198190406446,-0.04871252906513763,0.33452611576463864,0.688050566378247,-0.16372948749216756,0.8306316454399105,0.48964847025575964,0.11919997011538998,-0.10591263929674817,-0.4011890781327106,1.8491689704918812,-0.906083163548422,0.007872098580347686,-0.2812183777015856,-0.5236513396667263,5.131894866624145,-0.5858198190406446,-0.2812183777015856,0.228081190180689,-0.7760889340064466,-0.04871252906513763,0.17394576765407171,2.94951498403428,-0.4621081592112762,0.06384250748914849,0.5401492501085412,0.688050566378247,-0.34089288926430916,-0.8407704557687973,-0.5236513396667263,0.48964847025575964,-0.7120374352425395,-0.22216432068703482,1.8846964555914798,0.7836800160884329,2.589890921013961,-0.04871252906513763,-1.6665070292939557,0.007872098580347686,-0.5858198190406446,1.0129671489863166,0.5900489466309929,3.8063874677803375,-0.04871252906513763,-0.4011890781327106,-0.10591263929674817,0.5401492501085412,-0.6486147893595557,-0.8407704557687973,1.1442885584140452,-0.5236513396667263,2.157214859958303,-0.5858198190406446,0.2816075367943659,0.007872098580347686,0.48964847025575964,0.11919997011538998,0.6393489264185823,-0.04871252906513763,0.38683824468201267,0.11919997011538998,4.712282471751374,0.007872098580347686,-0.16372948749216756,-0.22216432068703482,0.9228702829555585,-0.7760889340064466,0.38683824468201267,-0.10591263929674817,-0.2812183777015856,-0.04871252906513763,4.0999276525600274,-0.7120374352425395,4.192232038011874,0.8770244243066478,0.38683824468201267,0.9681807864168185,-0.16372948749216756,-0.16372948749216756,0.688050566378247,0.228081190180689,-0.34089288926430916,0.8770244243066478,-0.04871252906513763,-0.22216432068703482,3.8063874677803375,-0.04871252906513763,0.007872098580347686,-0.34089288926430916,0.228081190180689,1.8491689704918812,-0.5858198190406446,0.9681807864168185,-0.5236513396667263,-0.4011890781327106,0.228081190180689,-0.16372948749216756,-0.34089288926430916,-0.04871252906513763,0.4385452506124256,-0.906083163548422,0.7836800160884329,0.007872098580347686,0.48964847025575964,0.38683824468201267,-2.9956170913795845,-0.906083163548422,-0.2812183777015856
2,937
Abnormal vertebral morphology
20
102
3.452422
0.000556
Q14108,P15586,O60826,Q15125,P04066,Q9UM00,Q14739,P16278,Q9UBM7,P54802,P10619,Q96L58,Q9UBN7,Q32P28,Q6NUK1,P04062,P48735,Q96AY3,P51798,Q9Y619
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
8,20,143,26,30,172,35,37,38,42,58,196,210,80,220,86,216,105,115,127
939,1778,942,1438,1334,2451,1118,143,1663,2299,212,948,1452,575,2015,1790,86,30,1674,58,714,2868,20,37,1352,646,961,1905,523,2531,2929,964,1468,2684,2898,527,2315,333,2885,1590,216,970,115,2640,42,1598,594,2229,2400,1150,1823,2042,1931,484,538,445,1156,2691,8,35,983,1503,26,1269,745,2054,80,986,1510,220,449,1949,343,1735,2844,1174,1280,1515,2161,1742,105,1852,346,196,1968,1091,1982,1986,2182,851,1766,38,210,1108,2287,172,1649,2621,2709,2802,1878,127
0.228081190180689,-0.22216432068703482,0.228081190180689,-0.04871252906513763,0.007872098580347686,-0.6486147893595557,0.11919997011538998,1.2712655154383892,-0.16372948749216756,-0.5236513396667263,1.0129671489863166,0.228081190180689,-0.04871252906513763,0.48964847025575964,-0.34089288926430916,-0.22216432068703482,1.8491689704918812,3.6169723053440874,-0.16372948749216756,2.3177619175977977,0.38683824468201267,-1.6665070292939557,3.887244197186541,3.4162772870291325,0.007872098580347686,0.4385452506124256,0.228081190180689,-0.2812183777015856,0.5401492501085412,-0.7120374352425395,-6.1260774561706235,0.228081190180689,-0.04871252906513763,-0.906083163548422,-2.0378507439803,0.5401492501085412,-0.5236513396667263,0.7836800160884329,-1.8873708060077286,-0.10591263929674817,1.0129671489863166,0.228081190180689,1.473918375909616,-0.8407704557687973,3.078582353860239,-0.10591263929674817,0.48964847025575964,-0.4621081592112762,-0.5858198190406446,0.11919997011538998,-0.22216432068703482,-0.34089288926430916,-0.2812183777015856,0.5900489466309929,0.5401492501085412,0.6393489264185823,0.11919997011538998,-0.906083163548422,4.712282471751374,3.4391717680711436,0.228081190180689,-0.04871252906513763,3.7024803541208557,0.06384250748914849,0.38683824468201267,-0.34089288926430916,1.919885894471246,0.228081190180689,-0.04871252906513763,1.0129671489863166,0.6393489264185823,-0.2812183777015856,0.7836800160884329,-0.16372948749216756,-1.451444818165324,0.11919997011538998,0.06384250748914849,-0.04871252906513763,-0.4011890781327106,-0.16372948749216756,1.628562285011634,-0.22216432068703482,0.7836800160884329,1.101010637080487,-0.2812183777015856,0.17394576765407171,-0.2812183777015856,-0.2812183777015856,-0.4011890781327106,0.33452611576463864,-0.16372948749216756,3.4162772870291325,1.057240248022844,0.17394576765407171,-0.4621081592112762,1.1870839548927827,-0.10591263929674817,-0.7760889340064466,-0.906083163548422,-1.1736688722168886,-0.22216432068703482,1.434245143990909
2,937
Abnormality of the vasculature of the eye
11
67
3.412786
0.000643
Q14739,P07602,P16278,P02786,P06865,Q13510,P10619,P01889,P07686,P04066,P06280
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
35,3,37,41,16,55,58,120,61,30,31
1881,2738,945,386,707,1446,1448,2628,120,41,30,128,1673,31,16,3,61,2017,58,2211,1459,37,1684,1794,523,1688,802,1463,586,1356,2534,2683,1360,2684,2898,1469,2869,2742,1367,2591,1478,362,1147,1150,1261,1932,823,1715,2691,55,1501,35,1503,1836,674,2159,1960,2262,2700,1746,411,685,2182,2187,2188,2287,2802
-0.2812183777015856,-1.0386067543300004,0.228081190180689,0.688050566378247,0.38683824468201267,-0.04871252906513763,-0.04871252906513763,-0.8407704557687973,1.434245143990909,3.1288971739076072,3.6169723053440874,1.3941514953495935,-0.16372948749216756,3.6169723053440874,4.024165938684547,5.131894866624145,2.1898966319486153,-0.34089288926430916,2.3177619175977977,-0.4621081592112762,-0.04871252906513763,3.4162772870291325,-0.16372948749216756,-0.22216432068703482,0.5401492501085412,-0.16372948749216756,0.33452611576463864,-0.04871252906513763,0.48964847025575964,0.007872098580347686,-0.7120374352425395,-0.906083163548422,0.007872098580347686,-0.906083163548422,-2.0378507439803,-0.04871252906513763,-1.6665070292939557,-1.0386067543300004,0.007872098580347686,-0.7760889340064466,-0.04871252906513763,0.7361572254974664,0.11919997011538998,0.11919997011538998,0.06384250748914849,-0.2812183777015856,0.33452611576463864,-0.16372948749216756,-0.906083163548422,2.5014551385438826,-0.04871252906513763,3.4391717680711436,-0.04871252906513763,-0.22216432068703482,0.4385452506124256,-0.4011890781327106,-0.2812183777015856,-0.4621081592112762,-0.906083163548422,-0.16372948749216756,0.688050566378247,0.4385452506124256,-0.4011890781327106,-0.4011890781327106,-0.4011890781327106,-0.4621081592112762,-1.1736688722168886
2,937