term
stringlengths
2
121
overlap
int64
6
281
setsize
int64
7
499
score
float64
1.96
10.6
pval
float64
0
0.05
edge
stringlengths
41
1.97k
type
stringclasses
5 values
subtype
stringclasses
24 values
subtype_key
stringclasses
24 values
edge_idxs
stringlengths
11
1.17k
ann_idxs
stringlengths
19
2.31k
ann_vals
stringlengths
124
9.94k
sig_size
int64
2.2k
3.73k
Oxidative phosphorylation
32
69
3.242521
0.001185
O75438,P13073,O14949,P20674,O75380,P21912,P14406,P03886,O75306,O96000,Q15904,O95139,P47985,O43676,Q9Y6M9,P22695,O75489,Q9UDW1,O43674,O95168,P00403,O95167,O14548,P06576,P24539,O75964,O00217,Q9Y487,O75251,P56556,Q7KZN9,Q86Y39
Processes and pathways
KEGG Pathways
msigdb_kegg
768,515,137,651,650,538,28,277,535,664,815,548,808,50,183,563,696,198,321,470,87,341,717,92,362,110,734,502,366,624,378,497
734,1875,717,137,321,50,2358,366,535,650,768,696,1138,110,548,341,470,806,1515,2155,664,1885,87,1000,277,953,92,1357,1583,1252,515,28,1056,1218,1932,3080,651,2855,3310,538,563,362,1517,2605,1405,881,1141,1059,1588,808,3463,3129,1258,931,624,1222,3584,815,1498,2280,378,497,1162,2840,198,1870,502,1512,183
0.5091440599781275,-0.2252475557449799,0.5285319592869173,2.1453820763492155,1.3008013122061457,3.107332731050088,-0.42111741427401633,1.1596174162013977,0.776099228012361,0.6247218507870246,0.4702158680735321,0.5671569209643074,0.17152746597699287,2.3623540515125967,0.7573430676997512,1.2481603149029503,0.9061027846832771,0.4310823742970927,-0.03458833609287247,-0.333399306791712,0.6055828069993638,-0.2252475557449799,2.5138506890054337,0.2724430641772754,1.4566081122737937,0.31242405485919195,2.4535901140386045,0.04856032582182117,-0.0765234222627171,0.11030317972784781,0.8134720365945656,3.5429255537908872,0.23224335926748166,0.13076838476814698,-0.24674747021415624,-0.7369966820229626,0.6247218507870246,-0.6225474635721432,-0.9241144775154201,0.776099228012361,0.7385400373905193,1.1774078138827289,-0.03458833609287247,-0.5099333245444402,0.027862332156932304,0.37199154172998977,0.17152746597699287,0.23224335926748166,-0.0765234222627171,0.4310823742970927,-1.1164377040450824,-0.7601130162085916,0.11030317972784781,0.33233340674752826,0.6628536231131278,0.13076838476814698,-1.5181631738777326,0.4310823742970927,-0.013711595274741894,-0.37712313988404206,1.1417856605713883,0.850660633843561,0.17152746597699287,-0.5998800653389513,1.824865383027324,-0.2038119362780547,0.850660633843561,-0.013711595274741894,1.9062125107768622
3,643
Protein localization to mitochondrion
19
66
3.235874
0.001213
O60830,Q9Y5J9,Q99595,P55786,P51572,Q9Y6C9,O00165,Q8N8Q8,Q5JRX3,Q9Y3D6,Q9Y584,Q8N4H5,Q9NS69,O95831,Q15070,Q15388,Q9GZY8,P30536,P49257
Processes and pathways
GO Biological process
msigdb_gobp
0,392,2,138,397,266,382,285,35,173,308,56,63,195,200,201,220,106,238
382,733,2982,1249,753,754,825,0,879,1106,999,3331,849,3507,195,697,2361,1930,2994,2094,2486,2487,3188,106,1587,2770,3312,238,2044,397,1257,138,2776,1093,200,201,2624,566,1896,35,1680,56,285,965,2746,2,866,2526,220,795,1046,63,945,1349,3212,1105,1436,3541,173,575,308,751,433,392,1020,266
1.1239123190922105,0.5091440599781275,-0.6909922588809689,0.11030317972784781,0.4897054676751104,0.4897054676751104,0.4114378359281686,5.89350676912575,0.37199154172998977,0.1918220918189678,0.2724430641772754,-0.947863266551478,0.3917410017874763,-1.2146610216914933,1.824865383027324,0.5671569209643074,-0.42111741427401633,-0.24674747021415624,-0.6909922588809689,-0.3116375849262432,-0.465386116003162,-0.465386116003162,-0.8065769270037231,2.377631431346862,-0.0765234222627171,-0.5772854996002308,-0.9241144775154201,1.6093549777202447,-0.28994201948861137,1.105997161876891,0.11030317972784781,2.1453820763492155,-0.5772854996002308,0.21206060116262693,1.8084952079083476,1.8084952079083476,-0.5099333245444402,0.7385400373905193,-0.2252475557449799,3.4495350664729076,-0.11870343366061006,2.9664513233824246,1.4566081122737937,0.31242405485919195,-0.5547632158192415,5.347123193165582,0.3917410017874763,-0.465386116003162,1.659614804060893,0.4506749437853009,0.25237072765834473,2.837587540785622,0.33233340674752826,0.06919953703395551,-0.8065769270037231,0.21206060116262693,0.027862332156932304,-1.2643087218937006,1.9546235974626718,0.7385400373905193,1.3704358233118867,0.5091440599781275,1.0157859516403132,1.1239123190922105,0.2724430641772754,1.5248649233353988
3,643
Anion transmembrane transport
23
50
3.223024
0.001268
P45880,P30825,Q9Y277,Q9UBX3,Q8TB61,P53985,Q9H2D1,O43808,P21796,Q9Y619,Q14728,P08183,Q86VD7,P55011,O60831,P51797,P04920,P12235,Q02978,Q9UHG3,P41440,Q9HC21,Q01650
Processes and pathways
GO Biological process
msigdb_gobp
261,771,661,144,410,409,286,779,278,694,814,303,177,678,434,191,450,581,79,84,213,619,376
1176,779,434,1733,1883,1580,450,1581,1445,303,1400,581,904,278,771,2318,213,261,1942,191,2219,1491,409,678,2222,376,79,1638,814,915,1301,960,177,1233,410,2180,2583,1014,286,1313,619,1103,144,84,1434,661,2030,694,1287,846
0.15117635458958095,0.4506749437853009,0.99761495810321,-0.16113177748554827,-0.2252475557449799,-0.0765234222627171,0.9611422765478006,-0.0765234222627171,0.007105158915106008,1.3877470096535027,0.027862332156932304,0.71968985939333,0.3521891223123161,1.4566081122737937,0.4702158680735321,-0.39908622494449625,1.692943464578411,1.5418361654019872,-0.24674747021415624,1.8412017569470738,-0.3552276637336356,-0.013711595274741894,1.0700404706148139,0.5863945968863824,-0.3552276637336356,1.1417856605713883,2.5885562139486704,-0.09758260109774661,0.4310823742970927,0.3521891223123161,0.08978035873173802,0.31242405485919195,1.9223823204371768,0.13076838476814698,1.0700404706148139,-0.333399306791712,-0.48762464822389984,0.2724430641772754,1.4566081122737937,0.08978035873173802,0.6818469365208409,0.21206060116262693,2.1296580535061174,2.5587558625495044,0.027862332156932304,0.6247218507870246,-0.2683121372291175,0.5863945968863824,0.11030317972784781,0.4114378359281686
3,643
Protein transporter activity
9
18
3.221635
0.001275
O60830,Q99595,P49755,Q9HD20,Q15388,P61619,Q9Y584,Q9UGP8,Q9NS69
Functions
GO Molecular function
msigdb_gomf
0,2,225,136,201,363,308,221,63
695,754,0,1106,697,225,2611,363,553,201,2012,2,136,63,221,308,751,392
0.5671569209643074,0.4897054676751104,5.89350676912575,0.1918220918189678,0.5671569209643074,1.64289728589414,-0.5099333245444402,1.1774078138827289,0.7573430676997512,1.8084952079083476,-0.2683121372291175,5.347123193165582,2.1610753620574217,2.837587540785622,1.659614804060893,1.3704358233118867,0.5091440599781275,1.1239123190922105
3,643
Primary mitochondrial disease
54
110
3.220421
0.00128
Q8NFF5,P13073,O14949,P39210,Q9UBX3,P20674,O75380,Q07021,Q5XKP0,Q96CU9,P03886,O75306,P47985,O95169,O43676,Q9Y584,Q9Y6M9,Q5JTZ9,P22695,Q8NI60,O75489,Q86YH6,Q5JPH6,O95831,P08559,Q6DKK2,P12235,Q6P4A7,Q8IUX1,Q99797,O43819,Q9NWS8,Q7LG56,Q9Y2R0,P00403,Q96RR1,Q5ST30,O75880,Q8N183,P82650,O60313,Q70HW3,Q9BUB7,Q9H3H1,O75251,O00217,Q9H9J2,P56556,Q7KZN9,Q86Y39,P0DJ07,Q9H0R6,Q5T2R2,Q9BW92
Drugs and Diseases
Protein Atlas Disease involvement
protein_atlas_disease_involvement
388,515,137,505,144,651,650,653,670,413,277,535,808,806,50,308,183,567,563,446,696,197,834,195,451,332,581,725,865,866,333,607,864,86,87,603,722,718,602,473,847,357,490,634,366,734,372,624,378,497,756,510,644,648
734,1875,137,50,2358,333,847,366,535,650,696,1323,718,806,2155,195,1885,87,1000,277,953,451,1357,1582,756,581,515,1056,3080,651,563,1517,2605,1405,505,1521,1939,808,2322,3129,1328,2045,1221,624,473,1747,1188,653,2280,1896,834,567,722,644,2509,670,332,725,357,378,2390,864,497,197,865,602,2062,388,446,1309,1961,1861,413,1163,1683,1863,1240,603,866,2234,1014,1427,2235,490,648,510,634,993,372,1017,607,2405,1652,1508,1349,3302,144,1389,897,1436,1788,86,1284,1923,2755,1018,1437,308,1925,183
0.5091440599781275,-0.2252475557449799,2.1453820763492155,3.107332731050088,-0.42111741427401633,1.2657472734377568,0.3917410017874763,1.1596174162013977,0.776099228012361,0.6247218507870246,0.5671569209643074,0.06919953703395551,0.5285319592869173,0.4310823742970927,-0.333399306791712,1.824865383027324,-0.2252475557449799,2.5138506890054337,0.2724430641772754,1.4566081122737937,0.31242405485919195,0.9611422765478006,0.04856032582182117,-0.0765234222627171,0.4897054676751104,0.71968985939333,0.8134720365945656,0.23224335926748166,-0.7369966820229626,0.6247218507870246,0.7385400373905193,-0.03458833609287247,-0.5099333245444402,0.027862332156932304,0.832089227524965,-0.03458833609287247,-0.24674747021415624,0.4310823742970927,-0.39908622494449625,-0.7601130162085916,0.06919953703395551,-0.28994201948861137,0.13076838476814698,0.6628536231131278,0.9061027846832771,-0.16113177748554827,0.15117635458958095,0.6247218507870246,-0.37712313988404206,-0.2252475557449799,0.4114378359281686,0.7385400373905193,0.5285319592869173,0.6438120248840904,-0.465386116003162,0.6055828069993638,1.2832942009953483,0.5285319592869173,1.1951570795527422,1.1417856605713883,-0.42111741427401633,0.3917410017874763,0.850660633843561,1.824865383027324,0.3917410017874763,0.7007922534137548,-0.28994201948861137,1.1239123190922105,0.9794004819604001,0.08978035873173802,-0.24674747021415624,-0.2038119362780547,1.0519984666463416,0.17152746597699287,-0.11870343366061006,-0.2038119362780547,0.13076838476814698,0.7007922534137548,0.3917410017874763,-0.3552276637336356,0.2724430641772754,0.027862332156932304,-0.3552276637336356,0.8691865207095048,0.6438120248840904,0.832089227524965,0.6628536231131278,0.29246072303462184,1.1596174162013977,0.2724430641772754,0.7007922534137548,-0.42111741427401633,-0.09758260109774661,-0.013711595274741894,0.06919953703395551,-0.900446979133231,2.1296580535061174,0.04856032582182117,0.37199154172998977,0.027862332156932304,-0.16113177748554827,2.5288465238651407,0.11030317972784781,-0.2252475557449799,-0.5547632158192415,0.2724430641772754,0.027862332156932304,1.3704358233118867,-0.2252475557449799,1.9062125107768622
3,643
Metalloprotease
11
28
3.213183
0.001313
Q9UIQ6,P78536,Q5JRX3,Q9NQW7,Q6P179,P55786,Q9BYT8,Q92905,Q7Z2K6,O75844,Q9NZ08
Functions
Protein Atlas Molecular function
protein_atlas_molecular_function
230,226,35,38,103,138,141,77,147,217,127
900,578,879,217,3530,1442,1663,2483,1401,955,325,138,226,35,103,147,77,938,841,866,141,3614,591,38,2024,127,230,620
0.3521891223123161,0.71968985939333,0.37199154172998977,1.659614804060893,-1.2643087218937006,0.007105158915106008,-0.11870343366061006,-0.465386116003162,0.027862332156932304,0.31242405485919195,1.3008013122061457,2.1453820763492155,1.64289728589414,3.4495350664729076,2.3928800946790516,2.0981172248521958,2.6034158117050517,0.33233340674752826,0.4114378359281686,0.3917410017874763,2.1296580535061174,-1.9455372097525145,0.71968985939333,3.314313786509081,-0.2683121372291175,2.239085653646518,1.64289728589414,0.6818469365208409
3,643
Sphingolipid metabolic process
19
34
3.209871
0.001328
O60512,P27544,P17900,Q6Y1H2,Q16739,P06280,Q96G23,P04062,Q9P035,Q9H2C2,O95470,Q06136,Q9NZJ7,Q8NCC3,P07602,P50897,Q16880,Q9NWW5,Q9NRA0
Processes and pathways
GO Biological process
msigdb_gobp
253,5,516,529,282,549,55,449,340,337,209,347,492,358,231,244,246,252,257
611,1879,253,209,449,549,1356,231,3508,1886,516,2488,5,2259,244,3049,347,3358,282,246,1896,529,358,55,1165,337,257,252,1130,798,3210,492,340,1785
0.6818469365208409,-0.2252475557449799,1.5756684289722063,1.7095549611048153,0.9611422765478006,0.7573430676997512,0.04856032582182117,1.6261440706577892,-1.2146610216914933,-0.2252475557449799,0.8134720365945656,-0.465386116003162,4.73149126850177,-0.37712313988404206,1.592529825004484,-0.7139566269396745,1.2305331089305223,-0.9716940090710073,1.4566081122737937,1.592529825004484,-0.2252475557449799,0.7948087934495096,1.1951570795527422,2.980646976640566,0.17152746597699287,1.2657472734377568,1.5756684289722063,1.592529825004484,0.1918220918189678,0.4506749437853009,-0.8065769270037231,0.8691865207095048,1.2657472734377568,-0.16113177748554827
3,643
Mitochondrial carrier domain superfamily [IPR023395]
13
24
3.193376
0.001406
Q9BSK2,O43772,Q9HC21,Q70HW3,Q9NZJ7,Q9Y6C9,Q9Y619,P12235,Q02978,Q9UBX3,Q86VD7,Q9H2D1,Q96H78
Sequence
InterPro Superfamily
interpro_homologous_superfamily
327,663,619,357,492,266,694,581,79,144,177,286,216
663,779,1733,1581,581,904,1491,2222,79,701,1269,357,177,2179,216,1014,327,286,619,492,144,1434,694,266
0.6055828069993638,0.4506749437853009,-0.16113177748554827,-0.0765234222627171,0.71968985939333,0.3521891223123161,-0.013711595274741894,-0.3552276637336356,2.5885562139486704,0.5671569209643074,0.11030317972784781,1.1951570795527422,1.9223823204371768,-0.333399306791712,1.6762968043598454,0.2724430641772754,1.3008013122061457,1.4566081122737937,0.6818469365208409,0.8691865207095048,2.1296580535061174,0.027862332156932304,0.5863945968863824,1.5248649233353988
3,643
SLC25 family of mitochondrial transporters
13
24
3.193376
0.001406
Q9BSK2,O43772,Q9HC21,Q70HW3,Q9NZJ7,Q9Y6C9,Q9Y619,P12235,Q02978,Q9UBX3,Q86VD7,Q9H2D1,Q96H78
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
327,663,619,357,492,266,694,581,79,144,177,286,216
663,779,1733,1581,581,904,1491,2222,79,701,1269,357,177,2179,216,1014,327,286,619,492,144,1434,694,266
0.6055828069993638,0.4506749437853009,-0.16113177748554827,-0.0765234222627171,0.71968985939333,0.3521891223123161,-0.013711595274741894,-0.3552276637336356,2.5885562139486704,0.5671569209643074,0.11030317972784781,1.1951570795527422,1.9223823204371768,-0.333399306791712,1.6762968043598454,0.2724430641772754,1.3008013122061457,1.4566081122737937,0.6818469365208409,0.8691865207095048,2.1296580535061174,0.027862332156932304,0.5863945968863824,1.5248649233353988
3,643
Mitochondrial substrate/solute carrier [IPR018108]
13
24
3.193376
0.001406
Q9BSK2,O43772,Q9HC21,Q70HW3,Q9NZJ7,Q9Y6C9,Q9Y619,P12235,Q02978,Q9UBX3,Q86VD7,Q9H2D1,Q96H78
Sequence
InterPro Repeat
interpro_repeat
327,663,619,357,492,266,694,581,79,144,177,286,216
663,779,1733,1581,581,904,1491,2222,79,701,1269,357,177,2179,216,1014,327,286,619,492,144,1434,694,266
0.6055828069993638,0.4506749437853009,-0.16113177748554827,-0.0765234222627171,0.71968985939333,0.3521891223123161,-0.013711595274741894,-0.3552276637336356,2.5885562139486704,0.5671569209643074,0.11030317972784781,1.1951570795527422,1.9223823204371768,-0.333399306791712,1.6762968043598454,0.2724430641772754,1.3008013122061457,1.4566081122737937,0.6818469365208409,0.8691865207095048,2.1296580535061174,0.027862332156932304,0.5863945968863824,1.5248649233353988
3,643
Thioredoxin, conserved site [IPR017937]
11
12
3.165535
0.001548
Q8IXB1,P30101,Q15084,O43396,P07237,Q9H3N1,Q14554,O95881,Q8NBS9,Q9H1E5,Q96JJ7
Sequence
InterPro Conserved site
interpro_conserved_site
129,352,419,383,41,297,108,237,402,181,350
383,237,41,443,352,108,419,129,402,350,181,297
1.1239123190922105,1.6093549777202447,3.2870083892475765,0.9794004819604001,1.2128654372087189,2.377631431346862,1.0339137070490352,2.223543950079106,1.0880399570282553,1.2305331089305223,1.9062125107768622,1.4050196301598754
3,643
Nadh dehydrogenase complex assembly
22
36
3.16138
0.00157
Q7L592,O75438,Q9H061,Q96CU9,P03886,O75306,O96000,Q9NW81,O95139,O95169,O43676,Q9Y6M9,O75489,O43674,Q15070,O95168,O95167,Q8N183,O75251,O00217,P56556,Q86Y39
Processes and pathways
GO Biological process
msigdb_gobp
774,768,148,413,277,535,664,691,548,806,50,183,696,321,200,470,341,602,366,734,624,497
734,321,50,2358,366,535,768,696,548,341,470,806,2155,664,277,953,2605,624,200,1498,2280,774,497,865,602,1309,413,2235,148,993,691,2405,1508,1349,1436,183
0.5091440599781275,1.3008013122061457,3.107332731050088,-0.42111741427401633,1.1596174162013977,0.776099228012361,0.4702158680735321,0.5671569209643074,0.7573430676997512,1.2481603149029503,0.9061027846832771,0.4310823742970927,-0.333399306791712,0.6055828069993638,1.4566081122737937,0.31242405485919195,-0.5099333245444402,0.6628536231131278,1.8084952079083476,-0.013711595274741894,-0.37712313988404206,0.4702158680735321,0.850660633843561,0.3917410017874763,0.7007922534137548,0.08978035873173802,1.0519984666463416,-0.3552276637336356,2.0981172248521958,0.29246072303462184,0.5863945968863824,-0.42111741427401633,-0.013711595274741894,0.06919953703395551,0.027862332156932304,1.9062125107768622
3,643
Sphingolipid metabolism
14
29
3.136198
0.001712
P51648,P27544,Q9NZJ7,P04062,P17900,P07602,P06280,Q8NBJ7,O95470,Q16739,Q16880,Q96G23,Q06136,Q9NRA0
Processes and pathways
Reactome Pathways
msigdb_reactome
32,5,492,449,516,231,549,44,209,282,246,55,347,257
1318,611,1879,1026,2035,209,449,549,1356,231,3508,2663,1886,516,2488,5,32,347,3358,282,246,44,55,2018,257,1130,3210,492,1785
0.06919953703395551,0.6818469365208409,-0.2252475557449799,0.25237072765834473,-0.28994201948861137,1.7095549611048153,0.9611422765478006,0.7573430676997512,0.04856032582182117,1.6261440706577892,-1.2146610216914933,-0.5323126699925248,-0.2252475557449799,0.8134720365945656,-0.465386116003162,4.73149126850177,3.476322734521235,1.2305331089305223,-0.9716940090710073,1.4566081122737937,1.592529825004484,3.204557850940264,2.980646976640566,-0.2683121372291175,1.5756684289722063,0.1918220918189678,-0.8065769270037231,0.8691865207095048,-0.16113177748554827
3,643
Respiratory electron transport
31
64
3.128125
0.001759
Q7L592,O75438,P13073,O14949,P20674,O75380,Q8N8Q8,P21912,P03886,O75306,O96000,O95139,P47985,O95169,O43676,Q9Y6M9,P22695,O75489,Q9UDW1,O43674,O43819,O95168,P00403,O95167,O75880,O14548,Q8N183,O75251,O00217,P56556,Q86Y39
Processes and pathways
Reactome Pathways
msigdb_reactome
774,768,515,137,651,650,285,538,277,535,664,548,808,806,50,183,563,696,198,321,333,470,87,341,718,717,602,366,734,624,497
734,1875,717,137,321,50,2358,333,366,535,650,768,696,718,548,341,470,806,1515,2155,664,1885,87,277,953,1357,1583,1252,515,3334,1056,1218,3080,651,538,563,2605,1405,881,2607,1521,808,3129,624,1146,2625,1498,2280,774,497,865,602,285,1309,1683,1535,2235,993,1017,2405,1508,1349,198,183
0.5091440599781275,-0.2252475557449799,0.5285319592869173,2.1453820763492155,1.3008013122061457,3.107332731050088,-0.42111741427401633,1.2657472734377568,1.1596174162013977,0.776099228012361,0.6247218507870246,0.4702158680735321,0.5671569209643074,0.5285319592869173,0.7573430676997512,1.2481603149029503,0.9061027846832771,0.4310823742970927,-0.03458833609287247,-0.333399306791712,0.6055828069993638,-0.2252475557449799,2.5138506890054337,1.4566081122737937,0.31242405485919195,0.04856032582182117,-0.0765234222627171,0.11030317972784781,0.8134720365945656,-0.947863266551478,0.23224335926748166,0.13076838476814698,-0.7369966820229626,0.6247218507870246,0.776099228012361,0.7385400373905193,-0.5099333245444402,0.027862332156932304,0.37199154172998977,-0.5099333245444402,-0.03458833609287247,0.4310823742970927,-0.7601130162085916,0.6628536231131278,0.17152746597699287,-0.5099333245444402,-0.013711595274741894,-0.37712313988404206,0.4702158680735321,0.850660633843561,0.3917410017874763,0.7007922534137548,1.4566081122737937,0.08978035873173802,-0.11870343366061006,-0.03458833609287247,-0.3552276637336356,0.29246072303462184,0.2724430641772754,-0.42111741427401633,-0.013711595274741894,0.06919953703395551,1.824865383027324,1.9062125107768622
3,643
Calcium-binding protein
6
22
3.126246
0.001771
Q9BRK5,Q02818,P80303,P43307,O43852,Q14257
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
105,74,43,14,16,20
16,1930,539,2161,1520,14,2676,1452,43,74,20,203,3383,2833,786,2129,3021,1906,792,105,1965,3242
4.095354306912875,-0.24674747021415624,0.776099228012361,-0.333399306791712,-0.03458833609287247,4.1449986542955966,-0.5323126699925248,0.007105158915106008,3.2321311079528603,2.633054429019238,3.8042718536546554,1.792091065872174,-0.9956073764657654,-0.5998800653389513,0.4506749437853009,-0.3116375849262432,-0.6909922588809689,-0.2252475557449799,0.4506749437853009,2.3928800946790516,-0.24674747021415624,-0.829925724951396
3,643
glycosyltransferase
16
31
3.12046
0.001806
O60512,Q9BT22,P04843,Q9H0U3,Q93063,P04844,Q8NAT1,Q8TCJ2,Q9BV10,Q9NYU2,Q10472,Q16739,Q9Y2G5,Q8N4A0,P46977,Q9P2E5
Functions
Panther Protein class
panther_protein_class
253,161,384,491,359,395,46,336,633,306,210,282,53,180,152,608
253,2801,2805,2951,384,395,1325,2364,1551,1030,1671,152,3544,1750,210,282,917,861,765,180,46,1422,336,359,631,161,633,491,306,608,53
1.5756684289722063,-0.5998800653389513,-0.5998800653389513,-0.6681029929832263,1.1239123190922105,1.105997161876891,0.06919953703395551,-0.42111741427401633,-0.055525473592154824,0.25237072765834473,-0.11870343366061006,2.06645172244257,-1.2892692909305767,-0.16113177748554827,1.7095549611048153,1.4566081122737937,0.3521891223123161,0.3917410017874763,0.4897054676751104,1.9062125107768622,3.190737263872994,0.027862332156932304,1.2657472734377568,1.1951570795527422,0.6628536231131278,2.018717139797755,0.6628536231131278,0.8691865207095048,1.3877470096535027,0.7007922534137548,3.0230894408053492
3,643
Abnormal muscle fiber morphology
28
75
3.111209
0.001863
P23786,P05067,Q99720,P50402,Q96RL7,P51114,P22626,Q9H2D1,O75648,P03886,P07196,P35637,Q9BUK6,O14979,P61978,O43676,Q9BTV4,Q8NI60,P51797,O95831,P12235,P11047,P00403,Q96RR1,Q13049,Q9Y4W6,Q70HW3,Q02809
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
255,385,656,396,532,408,527,286,536,277,291,418,45,425,679,50,311,446,191,195,581,580,87,603,598,620,357,613
1875,2905,425,50,2312,847,1290,2602,536,195,697,1885,87,1000,826,277,953,3533,385,1984,291,2991,1110,580,581,954,3246,527,255,1405,418,2492,1002,1671,396,1255,408,191,1491,2045,1221,2552,679,613,2223,598,2004,3055,3092,1119,834,1810,357,864,1756,1067,1564,2743,446,1961,1603,532,603,656,1906,311,45,286,843,1382,1436,2410,620,1479,973
-0.2252475557449799,-0.6452882514774274,1.0157859516403132,3.107332731050088,-0.39908622494449625,0.3917410017874763,0.08978035873173802,-0.5099333245444402,0.776099228012361,1.824865383027324,0.5671569209643074,-0.2252475557449799,2.5138506890054337,0.2724430641772754,0.4114378359281686,1.4566081122737937,0.31242405485919195,-1.2643087218937006,1.1239123190922105,-0.2683121372291175,1.4222538872246275,-0.6909922588809689,0.1918220918189678,0.71968985939333,0.71968985939333,0.31242405485919195,-0.8533532449353657,0.7948087934495096,1.5756684289722063,0.027862332156932304,1.0339137070490352,-0.465386116003162,0.2724430641772754,-0.11870343366061006,1.105997161876891,0.11030317972784781,1.0700404706148139,1.8412017569470738,-0.013711595274741894,-0.28994201948861137,0.13076838476814698,-0.48762464822389984,0.5863945968863824,0.6818469365208409,-0.3552276637336356,0.7007922534137548,-0.2683121372291175,-0.7139566269396745,-0.7369966820229626,0.1918220918189678,0.4114378359281686,-0.18244015934691968,1.1951570795527422,0.3917410017874763,-0.16113177748554827,0.23224335926748166,-0.055525473592154824,-0.5547632158192415,0.9794004819604001,-0.24674747021415624,-0.0765234222627171,0.7948087934495096,0.7007922534137548,0.6247218507870246,-0.2252475557449799,1.3356969350852728,3.204557850940264,1.4566081122737937,0.4114378359281686,0.04856032582182117,0.027862332156932304,-0.42111741427401633,0.6818469365208409,0.007105158915106008,0.31242405485919195
3,643
Anion transport
42
84
3.109779
0.001872
Q15041,P45880,P0CG08,P30825,P11166,Q9Y277,O14745,Q9UBX3,Q9H2D1,Q8TB61,P53985,P14174,O43865,O43808,P21796,Q9C0H2,Q9Y619,Q14728,P08183,Q86VD7,P55011,Q6KCM7,O60831,Q9Y6M7,P51797,Q08722,P04920,P12235,Q02978,Q7L0J3,Q9UHG3,P41440,Q96S66,Q9HC21,Q9NZJ7,P07602,P30536,P04083,Q15042,P28288,Q01650,O00400
Processes and pathways
GO Biological process
msigdb_gobp
915,261,638,771,514,661,876,144,286,410,409,150,404,779,278,689,694,814,303,177,678,701,434,846,191,830,450,581,79,863,84,213,219,619,492,231,106,484,741,759,376,123
3216,123,876,2905,1176,1026,779,404,434,1733,1883,1580,484,450,1581,1445,231,303,1400,638,2852,514,581,904,150,278,759,106,771,2318,213,261,1942,191,2219,1491,409,1061,678,1187,2222,376,79,830,1638,814,915,741,1893,1301,1527,960,701,3439,1269,3504,863,177,1233,410,2180,2583,3566,219,1127,1014,689,2644,286,2141,1313,619,1103,3210,492,144,84,1434,661,2030,694,1287,3305,846
-0.829925724951396,2.239085653646518,0.37199154172998977,-0.6452882514774274,0.15117635458958095,0.25237072765834473,0.4506749437853009,1.0700404706148139,0.99761495810321,-0.16113177748554827,-0.2252475557449799,-0.0765234222627171,0.8691865207095048,0.9611422765478006,-0.0765234222627171,0.007105158915106008,1.6261440706577892,1.3877470096535027,0.027862332156932304,0.6438120248840904,-0.6225474635721432,0.8134720365945656,0.71968985939333,0.3521891223123161,2.06645172244257,1.4566081122737937,0.4897054676751104,2.377631431346862,0.4702158680735321,-0.39908622494449625,1.692943464578411,1.5418361654019872,-0.24674747021415624,1.8412017569470738,-0.3552276637336356,-0.013711595274741894,1.0700404706148139,0.23224335926748166,0.5863945968863824,0.15117635458958095,-0.3552276637336356,1.1417856605713883,2.5885562139486704,0.4114378359281686,-0.09758260109774661,0.4310823742970927,0.3521891223123161,0.5091440599781275,-0.2252475557449799,0.08978035873173802,-0.03458833609287247,0.31242405485919195,0.5671569209643074,-1.0678500734626066,0.11030317972784781,-1.1899723271023945,0.3917410017874763,1.9223823204371768,0.13076838476814698,1.0700404706148139,-0.333399306791712,-0.48762464822389984,-1.390041774081608,1.659614804060893,0.1918220918189678,0.2724430641772754,0.5863945968863824,-0.5099333245444402,1.4566081122737937,-0.3116375849262432,0.08978035873173802,0.6818469365208409,0.21206060116262693,-0.8065769270037231,0.8691865207095048,2.1296580535061174,2.5587558625495044,0.027862332156932304,0.6247218507870246,-0.2683121372291175,0.5863945968863824,0.11030317972784781,-0.900446979133231,0.4114378359281686
3,643
Parkinsons disease
32
64
3.105577
0.001899
P45880,O75438,P13073,O14949,Q9Y277,P20674,O75380,P21912,P14406,P21796,P03886,O75306,O96000,O95139,P47985,O43676,Q9Y6M9,P22695,O75489,Q9UDW1,O43674,P12235,O95168,P00403,O95167,O14548,P06576,P60604,P24539,O75251,O00217,P56556
Processes and pathways
KEGG Pathways
msigdb_kegg
261,768,515,137,661,651,650,538,28,278,277,535,664,548,808,50,183,563,696,198,321,581,470,87,341,717,92,739,362,366,734,624
734,1875,717,137,321,50,2358,366,535,650,768,696,1138,548,341,470,806,1515,2155,664,1885,87,1000,277,953,1581,92,1357,1583,1252,581,904,515,28,1056,1218,1932,3080,651,278,538,3246,563,362,1517,2605,1405,881,1141,261,808,3463,3129,624,739,2776,3050,1498,2280,3567,198,661,2080,183
0.5091440599781275,-0.2252475557449799,0.5285319592869173,2.1453820763492155,1.3008013122061457,3.107332731050088,-0.42111741427401633,1.1596174162013977,0.776099228012361,0.6247218507870246,0.4702158680735321,0.5671569209643074,0.17152746597699287,0.7573430676997512,1.2481603149029503,0.9061027846832771,0.4310823742970927,-0.03458833609287247,-0.333399306791712,0.6055828069993638,-0.2252475557449799,2.5138506890054337,0.2724430641772754,1.4566081122737937,0.31242405485919195,-0.0765234222627171,2.4535901140386045,0.04856032582182117,-0.0765234222627171,0.11030317972784781,0.71968985939333,0.3521891223123161,0.8134720365945656,3.5429255537908872,0.23224335926748166,0.13076838476814698,-0.24674747021415624,-0.7369966820229626,0.6247218507870246,1.4566081122737937,0.776099228012361,-0.8533532449353657,0.7385400373905193,1.1774078138827289,-0.03458833609287247,-0.5099333245444402,0.027862332156932304,0.37199154172998977,0.17152746597699287,1.5418361654019872,0.4310823742970927,-1.1164377040450824,-0.7601130162085916,0.6628536231131278,0.5091440599781275,-0.5772854996002308,-0.7139566269396745,-0.013711595274741894,-0.37712313988404206,-1.390041774081608,1.824865383027324,0.6247218507870246,-0.28994201948861137,1.9062125107768622
3,643
Electron transfer activity
32
61
3.102318
0.00192
O75438,P13073,P20674,O75380,P30038,P21912,P14406,P03886,O75306,O96000,O95139,P47985,O43676,Q9Y6M9,O75489,Q9UDW1,O43674,P16435,O15460,O95168,P00403,O95167,Q13630,O14548,Q12797,P23378,O00217,O75251,P48163,P56556,Q7KZN9,P23368
Functions
GO Molecular function
msigdb_gomf
768,515,651,650,407,538,28,277,535,664,548,808,50,183,696,198,321,71,194,470,87,341,475,717,481,735,734,366,760,624,378,119
734,1875,717,194,1880,3121,321,50,2358,1693,366,535,650,768,696,548,341,470,806,1515,2155,664,2255,1885,87,277,953,1087,1357,1838,1252,3124,515,3334,28,3220,71,3080,651,538,119,735,2605,407,1405,881,2607,808,760,3129,624,481,475,2625,1498,2280,2741,378,1349,198,183
0.5091440599781275,-0.2252475557449799,0.5285319592869173,1.824865383027324,-0.2252475557449799,-0.7601130162085916,1.3008013122061457,3.107332731050088,-0.42111741427401633,-0.13988634815318823,1.1596174162013977,0.776099228012361,0.6247218507870246,0.4702158680735321,0.5671569209643074,0.7573430676997512,1.2481603149029503,0.9061027846832771,0.4310823742970927,-0.03458833609287247,-0.333399306791712,0.6055828069993638,-0.37712313988404206,-0.2252475557449799,2.5138506890054337,1.4566081122737937,0.31242405485919195,0.21206060116262693,0.04856032582182117,-0.2038119362780547,0.11030317972784781,-0.7601130162085916,0.8134720365945656,-0.947863266551478,3.5429255537908872,-0.829925724951396,2.7213338218562386,-0.7369966820229626,0.6247218507870246,0.776099228012361,2.2700794880847806,0.5091440599781275,-0.5099333245444402,1.0700404706148139,0.027862332156932304,0.37199154172998977,-0.5099333245444402,0.4310823742970927,0.4897054676751104,-0.7601130162085916,0.6628536231131278,0.8876671508686171,0.9061027846832771,-0.5099333245444402,-0.013711595274741894,-0.37712313988404206,-0.5547632158192415,1.1417856605713883,0.06919953703395551,1.824865383027324,1.9062125107768622
3,643
chaperone
24
80
3.078719
0.002079
Q8IXB1,P30533,Q9NWM8,Q8NBS9,P27797,Q9Y680,O95456,P07237,Q15084,O15260,Q99543,P13667,Q9UHV9,O14657,O14967,Q9Y2R0,P78318,Q96JJ7,Q9Y2G8,Q96KC8,P30101,Q14554,P27824,Q7KZN9
Functions
Panther Protein class
panther_protein_class
129,132,8,402,539,39,165,41,419,52,571,443,456,577,469,86,88,350,354,228,352,108,118,378
733,3617,577,469,52,3348,1578,1694,1324,2806,165,2807,1836,41,443,2667,1404,539,118,352,2818,906,132,1587,1740,1631,3190,1454,1362,88,2680,2111,3050,1190,1595,2685,3136,1494,2567,108,1332,419,2506,2388,1369,2225,1528,2781,378,2127,129,602,2062,402,1763,920,3365,3292,1040,1683,350,228,2642,1713,571,2453,1427,3444,1343,1346,1245,1278,8,660,456,3241,354,86,1576,39
0.5091440599781275,-2.0288519737109936,0.71968985939333,0.9061027846832771,3.0230894408053492,-0.9716940090710073,-0.0765234222627171,-0.13988634815318823,0.06919953703395551,-0.5998800653389513,1.9706953778300438,-0.5998800653389513,-0.2038119362780547,3.2870083892475765,0.9794004819604001,-0.5323126699925248,0.027862332156932304,0.776099228012361,2.285531889164803,1.2128654372087189,-0.5998800653389513,0.3521891223123161,2.192370287416088,-0.0765234222627171,-0.16113177748554827,-0.09758260109774661,-0.8065769270037231,0.007105158915106008,0.04856032582182117,2.5138506890054337,-0.5323126699925248,-0.3116375849262432,-0.7139566269396745,0.15117635458958095,-0.0765234222627171,-0.5323126699925248,-0.7601130162085916,-0.013711595274741894,-0.48762464822389984,2.377631431346862,0.06919953703395551,1.0339137070490352,-0.465386116003162,-0.42111741427401633,0.04856032582182117,-0.3552276637336356,-0.03458833609287247,-0.5772854996002308,1.1417856605713883,-0.3116375849262432,2.223543950079106,0.7007922534137548,-0.28994201948861137,1.0880399570282553,-0.16113177748554827,0.3521891223123161,-0.9716940090710073,-0.900446979133231,0.25237072765834473,-0.11870343366061006,1.2305331089305223,1.64289728589414,-0.5099333245444402,-0.13988634815318823,0.7385400373905193,-0.44321720897869366,0.027862332156932304,-1.0678500734626066,0.06919953703395551,0.06919953703395551,0.13076838476814698,0.11030317972784781,4.352908051790398,0.6247218507870246,0.9611422765478006,-0.829925724951396,1.2128654372087189,2.5288465238651407,-0.055525473592154824,3.314313786509081
3,643
Atpase coupled transmembrane transporter activity
10
29
3.065817
0.002171
O75027,Q9HD20,O15533,Q15388,P16615,O14678,Q9NUT2,P08183,P06576,P51797
Functions
GO Molecular function
msigdb_gomf
260,136,329,201,267,301,431,303,92,191
301,1176,329,260,976,1108,92,303,267,1553,2855,3310,1624,759,2318,1059,1588,191,2219,1222,1117,829,201,136,447,2074,431,1870,1512
1.3877470096535027,0.15117635458958095,1.2832942009953483,1.5418361654019872,0.29246072303462184,0.1918220918189678,2.4535901140386045,1.3877470096535027,1.5078566888617457,-0.055525473592154824,-0.6225474635721432,-0.9241144775154201,-0.09758260109774661,0.4897054676751104,-0.39908622494449625,0.23224335926748166,-0.0765234222627171,1.8412017569470738,-0.3552276637336356,0.13076838476814698,0.1918220918189678,0.4114378359281686,1.8084952079083476,2.1610753620574217,0.9794004819604001,-0.28994201948861137,1.0157859516403132,-0.2038119362780547,-0.013711595274741894
3,643
EF-hand domain [IPR002048]
9
50
3.063911
0.002185
Q9Y680,Q9NWM8,Q9BRK5,Q02818,P80303,Q96AY3,O43852,Q14257,Q8NI22
Sequence
InterPro Domain
interpro_domain
39,8,105,74,43,75,16,20,22
778,16,2986,2602,1733,1028,2092,3159,1930,977,3605,324,3336,1292,2160,2161,1520,1630,1182,2676,43,74,3574,1300,20,3093,203,1096,701,1269,1760,1643,786,557,22,75,3021,1501,1906,105,1965,1776,1912,8,692,1721,971,1434,1831,39
0.4506749437853009,4.095354306912875,-0.6909922588809689,-0.5099333245444402,-0.16113177748554827,0.25237072765834473,-0.3116375849262432,-0.7833062289105431,-0.24674747021415624,0.29246072303462184,-1.808991775160554,1.3008013122061457,-0.947863266551478,0.08978035873173802,-0.333399306791712,-0.333399306791712,-0.03458833609287247,-0.09758260109774661,0.15117635458958095,-0.5323126699925248,3.2321311079528603,2.633054429019238,-1.4409977440294737,0.08978035873173802,3.8042718536546554,-0.7369966820229626,1.792091065872174,0.21206060116262693,0.5671569209643074,0.11030317972784781,-0.16113177748554827,-0.09758260109774661,0.4506749437853009,0.7573430676997512,3.7655729970606435,2.633054429019238,-0.6909922588809689,-0.013711595274741894,-0.2252475557449799,2.3928800946790516,-0.24674747021415624,-0.16113177748554827,-0.2252475557449799,4.352908051790398,0.5863945968863824,-0.13988634815318823,0.31242405485919195,0.027862332156932304,-0.18244015934691968,3.314313786509081
3,643
Lysosomal lumen
21
37
3.029899
0.002446
P17900,Q8NBS9,O14773,P08236,P10253,Q9BWS9,P04066,P34059,P06280,Q9UM22,P54802,Q14108,Q8IV08,Q9UMR5,P04062,P61916,P38435,Q9NZJ7,P07602,Q8NHP8,P50897
Localization
GO Cellular component
msigdb_gocc
516,402,25,157,537,40,426,551,549,51,436,444,65,66,449,466,80,492,231,233,244
1289,2415,25,1026,449,426,549,1356,231,3508,2361,157,537,2663,3509,880,3555,582,1886,516,551,80,3628,1671,244,436,466,3358,444,65,402,233,1466,40,492,51,66
0.08978035873173802,-0.44321720897869366,3.661517338984293,0.25237072765834473,0.9611422765478006,1.0157859516403132,0.7573430676997512,0.04856032582182117,1.6261440706577892,-1.2146610216914933,-0.42111741427401633,2.034660375542446,0.776099228012361,-0.5323126699925248,-1.2146610216914933,0.37199154172998977,-1.3394678563793248,0.71968985939333,-0.2252475557449799,0.8134720365945656,0.7573430676997512,2.5587558625495044,-2.314556559776012,-0.11870343366061006,1.592529825004484,0.99761495810321,0.9244936801618757,-0.9716940090710073,0.9794004819604001,2.808677111591547,1.0880399570282553,1.6261440706577892,0.007105158915106008,3.3006721207392853,0.8691865207095048,3.037189084386894,2.808677111591547
3,643
Endoplasmic reticulum organization
23
50
3.020969
0.00252
Q8NFQ8,Q8N4V1,Q00765,Q9H6H4,Q9P2W9,Q6NUK4,Q96A33,Q9BRK0,Q7L5D6,O14976,O14657,Q5JRA6,Q8N766,Q8N5M9,O95197,Q9NQC3,P61619,Q15629,Q12981,Q15042,P49257,P57088,Q9NPA0
Processes and pathways
GO Biological process
msigdb_gobp
647,274,681,312,58,186,188,189,585,320,577,342,349,353,223,365,363,112,367,741,238,625,391
1318,1249,577,320,755,2357,1026,1484,1696,223,2035,1631,238,1522,625,1453,363,681,982,367,1332,915,741,3169,112,833,342,2060,186,585,274,353,349,647,837,188,189,2018,2022,2401,3527,312,1825,391,365,2592,1130,2077,1785,58
0.06919953703395551,0.11030317972784781,0.71968985939333,1.3008013122061457,0.4897054676751104,-0.42111741427401633,0.25237072765834473,-0.013711595274741894,-0.13988634815318823,1.64289728589414,-0.28994201948861137,-0.09758260109774661,1.6093549777202447,-0.03458833609287247,0.6628536231131278,0.007105158915106008,1.1774078138827289,0.5863945968863824,0.29246072303462184,1.1596174162013977,0.06919953703395551,0.3521891223123161,0.5091440599781275,-0.7833062289105431,2.3470478270665613,0.4114378359281686,1.2481603149029503,-0.28994201948861137,1.8575044941143102,0.71968985939333,1.473728476771492,1.2128654372087189,1.2305331089305223,0.6438120248840904,0.4114378359281686,1.8575044941143102,1.8575044941143102,-0.2683121372291175,-0.2683121372291175,-0.42111741427401633,-1.239439561156638,1.3356969350852728,-0.18244015934691968,1.1239123190922105,1.1774078138827289,-0.48762464822389984,0.1918220918189678,-0.28994201948861137,-0.16113177748554827,2.9094252815894692
3,643
Protein hydroxylation
10
17
3.011294
0.002601
Q12797,O75718,O15460,Q13162,P07237,Q96AY3,Q32P28,P13674,Q92791,Q96HE7
Processes and pathways
GO Biological process
msigdb_gobp
481,99,194,72,41,75,12,47,113,411
822,194,493,99,41,47,613,481,72,12,3099,113,75,411,1911,1777,3472
0.4114378359281686,1.824865383027324,0.850660633843561,2.423291779810149,3.2870083892475765,3.163027731650402,0.6818469365208409,0.8876671508686171,2.692012537294508,4.206660830311199,-0.7369966820229626,2.3470478270665613,2.633054429019238,1.0700404706148139,-0.2252475557449799,-0.16113177748554827,-1.1164377040450824
3,643
Glycosyltransferase activity
25
56
3.006161
0.002646
O60512,P04843,P04844,Q16739,Q9H488,P46977,Q7Z4H8,Q9UGN5,Q9BT22,Q8NAT1,Q9NYU2,Q9Y2G5,Q8N4A0,P04062,O15294,Q8TCJ2,Q10472,Q6ZXV5,Q9P2E5,Q02809,Q93063,Q9BV10,Q96L58,Q16880,O60568
Functions
GO Molecular function
msigdb_gomf
253,384,395,282,674,152,283,30,161,46,306,53,180,449,328,336,210,214,608,613,359,633,631,246,493
822,328,662,253,493,2801,2602,2805,3280,2951,449,384,395,1325,1356,3508,2256,2851,3352,2364,954,1551,1057,2216,1060,1671,152,613,1009,1750,210,831,282,246,917,214,2126,283,765,180,46,919,336,359,2067,631,161,633,2345,674,1915,306,608,30,997,53
0.4114378359281686,1.2832942009953483,0.6055828069993638,1.5756684289722063,0.850660633843561,-0.5998800653389513,-0.5099333245444402,-0.5998800653389513,-0.900446979133231,-0.6681029929832263,0.9611422765478006,1.1239123190922105,1.105997161876891,0.06919953703395551,0.04856032582182117,-1.2146610216914933,-0.37712313988404206,-0.6225474635721432,-0.9716940090710073,-0.42111741427401633,0.31242405485919195,-0.055525473592154824,0.23224335926748166,-0.3552276637336356,0.23224335926748166,-0.11870343366061006,2.06645172244257,0.6818469365208409,0.2724430641772754,-0.16113177748554827,1.7095549611048153,0.4114378359281686,1.4566081122737937,1.592529825004484,0.3521891223123161,1.692943464578411,-0.3116375849262432,1.4566081122737937,0.4897054676751104,1.9062125107768622,3.190737263872994,0.3521891223123161,1.2657472734377568,1.1951570795527422,-0.28994201948861137,0.6628536231131278,2.018717139797755,0.6628536231131278,-0.39908622494449625,0.6055828069993638,-0.2252475557449799,1.3877470096535027,0.7007922534137548,3.489685011935334,0.29246072303462184,3.0230894408053492
3,643
Glycosyltransferase
20
41
2.994429
0.00275
O60512,Q16739,Q9H488,P46977,Q7Z4H8,Q9UGN5,Q9BT22,Q8NAT1,Q9NYU2,Q9Y2G5,Q8N4A0,P04062,O15294,Q8TCJ2,Q10472,Q93063,Q9BV10,Q96L58,Q16880,O60568
Functions
Protein Atlas Molecular function
protein_atlas_molecular_function
253,282,674,152,283,30,161,46,306,53,180,449,328,336,210,359,633,631,246,493
328,662,253,493,2801,3280,2951,449,1325,2256,2851,3352,2364,954,1551,1057,2216,1060,152,1009,1750,210,831,282,246,917,283,765,180,46,919,336,359,631,161,633,2345,674,306,30,53
1.2832942009953483,0.6055828069993638,1.5756684289722063,0.850660633843561,-0.5998800653389513,-0.900446979133231,-0.6681029929832263,0.9611422765478006,0.06919953703395551,-0.37712313988404206,-0.6225474635721432,-0.9716940090710073,-0.42111741427401633,0.31242405485919195,-0.055525473592154824,0.23224335926748166,-0.3552276637336356,0.23224335926748166,2.06645172244257,0.2724430641772754,-0.16113177748554827,1.7095549611048153,0.4114378359281686,1.4566081122737937,1.592529825004484,0.3521891223123161,1.4566081122737937,0.4897054676751104,1.9062125107768622,3.190737263872994,0.3521891223123161,1.2657472734377568,1.1951570795527422,0.6628536231131278,2.018717139797755,0.6628536231131278,-0.39908622494449625,0.6055828069993638,1.3877470096535027,3.489685011935334,3.0230894408053492
3,643
Signaling
6
21
2.985925
0.002827
O15173,Q8WUJ1,Q7Z4V5,Q96GC9,O00264,Q96PC5
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
37,10,239,208,236,154
236,823,37,2207,1112,1739,1060,1557,553,1636,3382,342,239,1567,10,208,1239,154,1467,1921,750
1.6093549777202447,0.4114378359281686,3.314313786509081,-0.3552276637336356,0.1918220918189678,-0.16113177748554827,0.23224335926748166,-0.055525473592154824,0.7573430676997512,-0.09758260109774661,-0.9956073764657654,1.2481603149029503,1.6093549777202447,-0.055525473592154824,4.231204838358074,1.7261314689431049,0.13076838476814698,2.06645172244257,0.007105158915106008,-0.2252475557449799,0.5091440599781275
3,643
EF-hand domain pair [IPR011992]
9
55
2.982492
0.002859
Q9Y680,Q9NWM8,Q9BRK5,Q02818,P80303,Q96AY3,O43852,Q14257,Q8NI22
Sequence
InterPro Superfamily
interpro_homologous_superfamily
39,8,105,74,43,75,16,20,22
778,16,2986,2602,1733,1028,2092,3159,1930,977,3605,324,3336,1292,2160,2161,1520,1630,1182,1556,2676,1452,43,74,3574,1300,20,3093,203,1096,701,1269,2833,1760,1643,786,2129,557,22,75,3021,1501,1906,105,1965,1776,1912,430,8,692,1721,971,1434,1831,39
0.4506749437853009,4.095354306912875,-0.6909922588809689,-0.5099333245444402,-0.16113177748554827,0.25237072765834473,-0.3116375849262432,-0.7833062289105431,-0.24674747021415624,0.29246072303462184,-1.808991775160554,1.3008013122061457,-0.947863266551478,0.08978035873173802,-0.333399306791712,-0.333399306791712,-0.03458833609287247,-0.09758260109774661,0.15117635458958095,-0.055525473592154824,-0.5323126699925248,0.007105158915106008,3.2321311079528603,2.633054429019238,-1.4409977440294737,0.08978035873173802,3.8042718536546554,-0.7369966820229626,1.792091065872174,0.21206060116262693,0.5671569209643074,0.11030317972784781,-0.5998800653389513,-0.16113177748554827,-0.09758260109774661,0.4506749437853009,-0.3116375849262432,0.7573430676997512,3.7655729970606435,2.633054429019238,-0.6909922588809689,-0.013711595274741894,-0.2252475557449799,2.3928800946790516,-0.24674747021415624,-0.16113177748554827,-0.2252475557449799,1.0157859516403132,4.352908051790398,0.5863945968863824,-0.13988634815318823,0.31242405485919195,0.027862332156932304,-0.18244015934691968,3.314313786509081
3,643
Mitochondrial transport
30
95
2.98238
0.00286
O60830,P23786,Q99595,Q9Y5J9,Q96EK5,P45880,P55786,O00165,P51572,Q9UBX3,Q8N8Q8,Q5JRX3,Q14849,Q9Y3D6,Q9Y5J7,Q9Y512,Q9Y584,Q8N4H5,Q3ZCQ8,Q9NS69,O95831,Q15070,Q15388,P12235,P06576,Q9GZY8,P30536,P24539,O75964,P49257
Processes and pathways
GO Biological process
msigdb_gobp
0,255,2,392,521,261,138,382,397,144,285,35,555,173,433,575,308,56,566,63,195,200,201,581,92,220,106,362,110,238
382,733,753,754,825,663,0,2419,1695,879,1138,110,1106,999,3331,849,3507,195,697,1000,1734,1581,92,2361,2604,2994,581,1932,2487,255,362,1517,2818,3188,106,3312,1141,2998,261,3463,2820,238,2044,1742,709,397,1257,138,1258,931,2776,1093,555,200,201,2624,3382,566,1896,35,1269,1680,1760,1643,56,285,965,521,3107,2746,2,866,2072,2526,220,795,1046,2074,63,1349,3212,144,1105,1434,609,1436,3541,173,575,308,751,433,392,1020,1174
1.1239123190922105,0.5091440599781275,0.4897054676751104,0.4897054676751104,0.4114378359281686,0.6055828069993638,5.89350676912575,-0.44321720897869366,-0.13988634815318823,0.37199154172998977,0.17152746597699287,2.3623540515125967,0.1918220918189678,0.2724430641772754,-0.947863266551478,0.3917410017874763,-1.2146610216914933,1.824865383027324,0.5671569209643074,0.2724430641772754,-0.16113177748554827,-0.0765234222627171,2.4535901140386045,-0.42111741427401633,-0.5099333245444402,-0.6909922588809689,0.71968985939333,-0.24674747021415624,-0.465386116003162,1.5756684289722063,1.1774078138827289,-0.03458833609287247,-0.5998800653389513,-0.8065769270037231,2.377631431346862,-0.9241144775154201,0.17152746597699287,-0.6909922588809689,1.5418361654019872,-1.1164377040450824,-0.5998800653389513,1.6093549777202447,-0.28994201948861137,-0.16113177748554827,0.5478694768628188,1.105997161876891,0.11030317972784781,2.1453820763492155,0.11030317972784781,0.33233340674752826,-0.5772854996002308,0.21206060116262693,0.7573430676997512,1.8084952079083476,1.8084952079083476,-0.5099333245444402,-0.9956073764657654,0.7385400373905193,-0.2252475557449799,3.4495350664729076,0.11030317972784781,-0.11870343366061006,-0.16113177748554827,-0.09758260109774661,2.9664513233824246,1.4566081122737937,0.31242405485919195,0.8134720365945656,-0.7369966820229626,-0.5547632158192415,5.347123193165582,0.3917410017874763,-0.28994201948861137,-0.465386116003162,1.659614804060893,0.4506749437853009,0.25237072765834473,-0.28994201948861137,2.837587540785622,0.06919953703395551,-0.8065769270037231,2.1296580535061174,0.21206060116262693,0.027862332156932304,0.7007922534137548,0.027862332156932304,-1.2643087218937006,1.9546235974626718,0.7385400373905193,1.3704358233118867,0.5091440599781275,1.0157859516403132,1.1239123190922105,0.2724430641772754,0.17152746597699287
3,643
Copii coated er to golgi transport vesicle
18
41
2.982171
0.002862
Q9Y282,Q3ZAQ7,O95070,P05067,P30511,P49755,Q15437,O14653,Q9Y3A6,Q96RQ1,P04439,P10321,Q969X5,Q5BJH7,Q969M3,Q9BVK6,P49257,Q8NI22
Localization
GO Cellular component
msigdb_gocc
162,643,67,385,6,225,617,512,268,76,579,48,729,146,728,212,238,22
512,755,1834,2602,1179,1696,67,1619,3332,1139,579,385,48,6,238,225,979,2372,1034,1189,982,1299,3169,1707,617,643,146,3098,22,728,729,76,212,2022,995,971,162,268,1789,873,2082
0.8134720365945656,0.4897054676751104,-0.2038119362780547,-0.5099333245444402,0.15117635458958095,-0.13988634815318823,2.794183911350097,-0.09758260109774661,-0.947863266551478,0.17152746597699287,0.71968985939333,1.1239123190922105,3.135226461008061,4.673387267370069,1.6093549777202447,1.64289728589414,0.29246072303462184,-0.42111741427401633,0.25237072765834473,0.15117635458958095,0.29246072303462184,0.08978035873173802,-0.7833062289105431,-0.13988634815318823,0.6818469365208409,0.6438120248840904,2.0981172248521958,-0.7369966820229626,3.7655729970606435,0.5285319592869173,0.5285319592869173,2.6182485118089542,1.7095549611048153,-0.2683121372291175,0.29246072303462184,0.31242405485919195,2.0027419959879986,1.5078566888617457,-0.16113177748554827,0.3917410017874763,-0.28994201948861137
3,643
Protein disulfide isomerase activity
9
11
2.980397
0.002879
P30101,Q15084,P30040,P07237,Q14554,Q92643,Q8NBS9,Q9BS26,Q96JJ7
Functions
GO Molecular function
msigdb_gomf
352,419,386,41,108,187,402,251,350
41,443,386,352,108,419,989,402,187,350,251
3.2870083892475765,0.9794004819604001,1.1239123190922105,1.2128654372087189,2.377631431346862,1.0339137070490352,0.29246072303462184,1.0880399570282553,1.8575044941143102,1.2305331089305223,1.592529825004484
3,643
Nonalcoholic fatty liver disease
28
59
2.97737
0.002907
O75438,P13073,O14949,P20674,O75380,P54619,P21912,P14406,O75306,O96000,P31751,O95139,P47985,O43676,Q9Y6M9,P22695,O75489,Q9UDW1,O43674,Q96GC9,O95168,P00403,O95167,O14548,O75251,O00217,P56556,Q86Y39
Processes and pathways
WikiPathways
msigdb_wp
768,515,137,651,650,540,538,28,535,664,550,548,808,50,183,563,696,198,321,208,470,87,341,717,366,734,624,497
734,1875,717,2906,137,321,50,2358,366,535,650,768,696,548,341,470,806,1515,2155,664,1885,87,1355,1357,1583,1252,515,28,1056,1218,3080,651,538,563,2605,1405,2770,550,881,808,2550,3129,2044,1742,540,1062,624,2108,1998,3382,1498,2280,497,208,1342,2405,1349,198,183
0.5091440599781275,-0.2252475557449799,0.5285319592869173,-0.6452882514774274,2.1453820763492155,1.3008013122061457,3.107332731050088,-0.42111741427401633,1.1596174162013977,0.776099228012361,0.6247218507870246,0.4702158680735321,0.5671569209643074,0.7573430676997512,1.2481603149029503,0.9061027846832771,0.4310823742970927,-0.03458833609287247,-0.333399306791712,0.6055828069993638,-0.2252475557449799,2.5138506890054337,0.04856032582182117,0.04856032582182117,-0.0765234222627171,0.11030317972784781,0.8134720365945656,3.5429255537908872,0.23224335926748166,0.13076838476814698,-0.7369966820229626,0.6247218507870246,0.776099228012361,0.7385400373905193,-0.5099333245444402,0.027862332156932304,-0.5772854996002308,0.7573430676997512,0.37199154172998977,0.4310823742970927,-0.48762464822389984,-0.7601130162085916,-0.28994201948861137,-0.16113177748554827,0.776099228012361,0.23224335926748166,0.6628536231131278,-0.3116375849262432,-0.2683121372291175,-0.9956073764657654,-0.013711595274741894,-0.37712313988404206,0.850660633843561,1.7261314689431049,0.06919953703395551,-0.42111741427401633,0.06919953703395551,1.824865383027324,1.9062125107768622
3,643
Electron transport
31
57
2.976798
0.002913
O43396,O75438,O14949,Q86YB8,O75380,Q96HE7,P21912,Q96CU9,P03886,O75306,O96000,Q9H3N1,O95139,O43169,P47985,O43676,Q9H1E5,Q9Y6M9,P22695,O75489,Q9UDW1,O43674,Q9Y241,Q6DKK2,O95168,P00403,O95167,O75251,O00217,P56556,Q86Y39
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
383,768,137,530,650,411,538,413,277,535,664,297,548,174,808,50,181,183,563,696,198,321,593,332,470,87,341,366,734,624,497
734,1875,137,174,383,321,50,2358,366,535,650,768,696,548,341,470,806,1515,2155,1180,664,1885,87,277,953,1357,3334,1056,3080,538,3081,563,2605,1405,881,3431,2607,808,3129,624,2625,1498,2280,2056,332,497,530,413,411,2890,181,297,2405,1349,198,593,183
0.5091440599781275,-0.2252475557449799,2.1453820763492155,1.9385192969684373,1.1239123190922105,1.3008013122061457,3.107332731050088,-0.42111741427401633,1.1596174162013977,0.776099228012361,0.6247218507870246,0.4702158680735321,0.5671569209643074,0.7573430676997512,1.2481603149029503,0.9061027846832771,0.4310823742970927,-0.03458833609287247,-0.333399306791712,0.15117635458958095,0.6055828069993638,-0.2252475557449799,2.5138506890054337,1.4566081122737937,0.31242405485919195,0.04856032582182117,-0.947863266551478,0.23224335926748166,-0.7369966820229626,0.776099228012361,-0.7369966820229626,0.7385400373905193,-0.5099333245444402,0.027862332156932304,0.37199154172998977,-1.0678500734626066,-0.5099333245444402,0.4310823742970927,-0.7601130162085916,0.6628536231131278,-0.5099333245444402,-0.013711595274741894,-0.37712313988404206,-0.28994201948861137,1.2832942009953483,0.850660633843561,0.7948087934495096,1.0519984666463416,1.0700404706148139,-0.6225474635721432,1.9062125107768622,1.4050196301598754,-0.42111741427401633,0.06919953703395551,1.824865383027324,0.71968985939333,1.9062125107768622
3,643
Oxidoreduction driven active transmembrane transporter activity
22
38
2.975864
0.002922
O75438,P13073,P20674,O75380,P03886,O75306,O96000,O95139,P47985,O43676,Q9Y6M9,O75489,Q9UDW1,O43674,O95168,P00403,O95167,O14548,O75251,O00217,P56556,Q7KZN9
Functions
GO Molecular function
msigdb_gomf
768,515,651,650,277,535,664,548,808,50,183,696,198,321,470,87,341,717,366,734,624,378
734,1875,717,321,50,2358,366,535,650,768,696,548,341,470,806,1515,2155,664,1885,87,277,953,1357,1252,515,3080,651,2605,881,808,3129,624,1498,2280,378,1349,198,183
0.5091440599781275,-0.2252475557449799,0.5285319592869173,1.3008013122061457,3.107332731050088,-0.42111741427401633,1.1596174162013977,0.776099228012361,0.6247218507870246,0.4702158680735321,0.5671569209643074,0.7573430676997512,1.2481603149029503,0.9061027846832771,0.4310823742970927,-0.03458833609287247,-0.333399306791712,0.6055828069993638,-0.2252475557449799,2.5138506890054337,1.4566081122737937,0.31242405485919195,0.04856032582182117,0.11030317972784781,0.8134720365945656,-0.7369966820229626,0.6247218507870246,-0.5099333245444402,0.37199154172998977,0.4310823742970927,-0.7601130162085916,0.6628536231131278,-0.013711595274741894,-0.37712313988404206,1.1417856605713883,0.06919953703395551,1.824865383027324,1.9062125107768622
3,643
Mitochondrial transmembrane transport
23
57
2.971642
0.002962
P23786,O60830,Q99595,O75027,Q9NWR8,Q9H2D1,P21796,O43772,Q9Y619,Q9NUT2,Q3ZCQ8,O96008,Q9BSK2,O95831,Q15388,P50416,P12235,Q9H4I9,Q9UJZ1,P06576,Q9Y4W6,P24539,O75964
Processes and pathways
GO Biological process
msigdb_gobp
255,0,2,260,659,286,278,663,694,431,566,697,327,195,201,709,581,78,609,92,620,362,110
754,825,663,0,260,879,1733,1138,110,1106,1028,1580,195,697,1000,1581,92,2994,581,904,1932,278,255,362,1517,1141,3463,709,1491,1258,931,2222,201,566,725,786,1159,1961,965,3633,2583,2,1906,2072,1014,327,286,78,1313,1046,1314,431,659,1434,609,620,694
0.4897054676751104,0.4114378359281686,0.6055828069993638,5.89350676912575,1.5418361654019872,0.37199154172998977,-0.16113177748554827,0.17152746597699287,2.3623540515125967,0.1918220918189678,0.25237072765834473,-0.0765234222627171,1.824865383027324,0.5671569209643074,0.2724430641772754,-0.0765234222627171,2.4535901140386045,-0.6909922588809689,0.71968985939333,0.3521891223123161,-0.24674747021415624,1.4566081122737937,1.5756684289722063,1.1774078138827289,-0.03458833609287247,0.17152746597699287,-1.1164377040450824,0.5478694768628188,-0.013711595274741894,0.11030317972784781,0.33233340674752826,-0.3552276637336356,1.8084952079083476,0.7385400373905193,0.5285319592869173,0.4506749437853009,0.17152746597699287,-0.24674747021415624,0.31242405485919195,-3.0906760096205748,-0.48762464822389984,5.347123193165582,-0.2252475557449799,-0.28994201948861137,0.2724430641772754,1.3008013122061457,1.4566081122737937,2.6034158117050517,0.08978035873173802,0.25237072765834473,0.08978035873173802,1.0157859516403132,0.6247218507870246,0.027862332156932304,0.7007922534137548,0.6818469365208409,0.5863945968863824
3,643
Intracellular protein transmembrane transport
10
26
2.968509
0.002992
O60830,Q99595,O95831,Q15388,P31751,P61619,O75298,Q15629,Q99442,Q9UGP8
Processes and pathways
GO Biological process
msigdb_gobp
0,2,195,201,550,363,546,112,467,221
754,825,0,546,1137,1106,195,697,2994,1217,550,1522,2611,2772,2496,363,3378,201,112,566,1307,1373,467,2,1046,221
0.4897054676751104,0.4114378359281686,5.89350676912575,0.7573430676997512,0.17152746597699287,0.1918220918189678,1.824865383027324,0.5671569209643074,-0.6909922588809689,0.13076838476814698,0.7573430676997512,-0.03458833609287247,-0.5099333245444402,-0.5772854996002308,-0.465386116003162,1.1774078138827289,-0.9956073764657654,1.8084952079083476,2.3470478270665613,0.7385400373905193,0.08978035873173802,0.04856032582182117,0.9244936801618757,5.347123193165582,0.25237072765834473,1.659614804060893
3,643
Cytochrome complex assembly
11
16
2.95625
0.003114
Q9BSK2,Q15070,Q6DKK2,P53701,Q69YU5,O43819,Q7KZN9,Q8N8Q8,Q9Y2R0,O75880,P0DJ07
Processes and pathways
GO Biological process
msigdb_gobp
327,200,332,517,145,333,378,285,86,718,756
333,718,756,808,517,200,145,332,378,285,1683,1427,327,1245,1436,86
1.2657472734377568,0.5285319592869173,0.4897054676751104,0.4310823742970927,0.8134720365945656,1.8084952079083476,2.113903150898959,1.2832942009953483,1.1417856605713883,1.4566081122737937,-0.11870343366061006,0.027862332156932304,1.3008013122061457,0.13076838476814698,0.027862332156932304,2.5288465238651407
3,643
Respiratory chain
24
42
2.956058
0.003116
O75438,O14949,O75380,Q96CU9,P03886,O75306,O96000,O95139,P47985,O43676,Q9Y6M9,P22695,O75489,Q9UDW1,O43674,Q9Y241,Q6DKK2,O95168,P00403,O95167,O75251,O00217,P56556,Q86Y39
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
768,137,650,413,277,535,664,548,808,50,183,563,696,198,321,593,332,470,87,341,366,734,624,497
734,1875,137,321,50,2358,366,535,650,768,696,548,341,470,806,1515,2155,664,1885,87,277,953,1357,1056,3080,563,2605,881,808,3129,624,1498,2280,332,497,413,2890,2405,1349,198,593,183
0.5091440599781275,-0.2252475557449799,2.1453820763492155,1.3008013122061457,3.107332731050088,-0.42111741427401633,1.1596174162013977,0.776099228012361,0.6247218507870246,0.4702158680735321,0.5671569209643074,0.7573430676997512,1.2481603149029503,0.9061027846832771,0.4310823742970927,-0.03458833609287247,-0.333399306791712,0.6055828069993638,-0.2252475557449799,2.5138506890054337,1.4566081122737937,0.31242405485919195,0.04856032582182117,0.23224335926748166,-0.7369966820229626,0.7385400373905193,-0.5099333245444402,0.37199154172998977,0.4310823742970927,-0.7601130162085916,0.6628536231131278,-0.013711595274741894,-0.37712313988404206,1.2832942009953483,0.850660633843561,1.0519984666463416,-0.6225474635721432,-0.42111741427401633,0.06919953703395551,1.824865383027324,0.71968985939333,1.9062125107768622
3,643
Antigen presentation folding assembly and peptide loading of class i mhc
9
19
2.954271
0.003134
P30101,P30511,Q6P179,O15533,P51572,P10321,P27824,P27797,Q9NZ08
Processes and pathways
Reactome Pathways
msigdb_reactome
352,6,103,329,397,48,118,539,127
329,1696,1619,3332,1139,579,48,539,118,352,6,397,2372,1034,829,1707,103,127,873
1.2832942009953483,-0.13988634815318823,-0.09758260109774661,-0.947863266551478,0.17152746597699287,0.71968985939333,3.135226461008061,0.776099228012361,2.285531889164803,1.2128654372087189,4.673387267370069,1.105997161876891,-0.42111741427401633,0.25237072765834473,0.4114378359281686,-0.13988634815318823,2.3928800946790516,2.239085653646518,0.3917410017874763
3,643
Sphingolipid biosynthetic process
11
20
2.948388
0.003194
O60512,P27544,P04062,Q9P035,Q6Y1H2,O95470,Q16739,Q16880,Q96G23,Q06136,Q9NRA0
Processes and pathways
GO Biological process
msigdb_gobp
253,5,449,340,529,209,282,246,55,347,257
611,1879,253,209,449,2488,5,3049,347,3358,282,246,1896,529,55,1165,257,1130,340,1785
0.6818469365208409,-0.2252475557449799,1.5756684289722063,1.7095549611048153,0.9611422765478006,-0.465386116003162,4.73149126850177,-0.7139566269396745,1.2305331089305223,-0.9716940090710073,1.4566081122737937,1.592529825004484,-0.2252475557449799,0.7948087934495096,2.980646976640566,0.17152746597699287,1.5756684289722063,0.1918220918189678,1.2657472734377568,-0.16113177748554827
3,643
Protein targeting to mitochondrion
16
51
2.9359
0.003326
O60830,Q9Y5J9,Q99595,Q5JRX3,O95831,P55786,P51572,O00165,Q9Y3D6,Q15388,P30536,P49257,Q9Y584,Q8N4H5,Q9GZY8,Q9NS69
Processes and pathways
GO Biological process
msigdb_gobp
0,392,2,35,195,138,397,382,173,201,106,238,308,56,220,63
382,733,753,754,825,0,879,1106,999,3331,849,3507,195,697,2361,2994,2487,106,3312,238,2044,397,138,2776,1093,201,2624,566,1896,35,1680,56,2746,2,866,2526,220,795,1046,63,1349,3212,1105,3541,173,575,308,751,433,392,1020
1.1239123190922105,0.5091440599781275,0.4897054676751104,0.4897054676751104,0.4114378359281686,5.89350676912575,0.37199154172998977,0.1918220918189678,0.2724430641772754,-0.947863266551478,0.3917410017874763,-1.2146610216914933,1.824865383027324,0.5671569209643074,-0.42111741427401633,-0.6909922588809689,-0.465386116003162,2.377631431346862,-0.9241144775154201,1.6093549777202447,-0.28994201948861137,1.105997161876891,2.1453820763492155,-0.5772854996002308,0.21206060116262693,1.8084952079083476,-0.5099333245444402,0.7385400373905193,-0.2252475557449799,3.4495350664729076,-0.11870343366061006,2.9664513233824246,-0.5547632158192415,5.347123193165582,0.3917410017874763,-0.465386116003162,1.659614804060893,0.4506749437853009,0.25237072765834473,2.837587540785622,0.06919953703395551,-0.8065769270037231,0.21206060116262693,-1.2643087218937006,1.9546235974626718,0.7385400373905193,1.3704358233118867,0.5091440599781275,1.0157859516403132,1.1239123190922105,0.2724430641772754
3,643
Udp glycosyltransferase activity
13
24
2.924352
0.003452
O60512,Q93063,O15294,O60568,Q8NAT1,Q9NYU2,Q10472,Q96L58,Q16739,Q8N4A0,Q9P2E5,Q16880,Q7Z4H8
Functions
GO Molecular function
msigdb_gomf
253,359,328,493,46,306,210,631,282,180,608,246,283
328,662,253,493,2805,1356,3508,954,1551,1057,1671,1750,210,282,246,283,765,180,46,919,359,631,306,608
1.2832942009953483,0.6055828069993638,1.5756684289722063,0.850660633843561,-0.5998800653389513,0.04856032582182117,-1.2146610216914933,0.31242405485919195,-0.055525473592154824,0.23224335926748166,-0.11870343366061006,-0.16113177748554827,1.7095549611048153,1.4566081122737937,1.592529825004484,1.4566081122737937,0.4897054676751104,1.9062125107768622,3.190737263872994,0.3521891223123161,1.1951570795527422,0.6628536231131278,1.3877470096535027,0.7007922534137548
3,643
Intrinsic component of mitochondrial inner membrane
20
36
2.912631
0.003584
Q13505,O60830,Q99595,Q9NWR8,Q9NX63,Q8N8Q8,Q5XKP0,Q9UG56,Q9Y512,Q16891,Q15070,Q6P4A7,Q9H4I9,Q9H3K2,O43819,Q9Y2R0,O75880,Q9Y4W6,Q9HC21,P0DJ07
Localization
GO Cellular component
msigdb_gocc
519,0,2,659,544,285,670,159,575,700,200,725,78,468,333,86,718,620,619,756
754,333,0,1695,718,1580,756,2720,1184,2222,519,200,2625,700,1896,670,725,1010,285,1159,3633,2583,2,1966,468,78,1313,1101,619,1278,659,544,159,86,620,575
0.4897054676751104,1.2657472734377568,5.89350676912575,-0.13988634815318823,0.5285319592869173,-0.0765234222627171,0.4897054676751104,-0.5547632158192415,0.15117635458958095,-0.3552276637336356,0.8134720365945656,1.8084952079083476,-0.5099333245444402,0.5671569209643074,-0.2252475557449799,0.6055828069993638,0.5285319592869173,0.2724430641772754,1.4566081122737937,0.17152746597699287,-3.0906760096205748,-0.48762464822389984,5.347123193165582,-0.24674747021415624,0.9244936801618757,2.6034158117050517,0.08978035873173802,0.21206060116262693,0.6818469365208409,0.11030317972784781,0.6247218507870246,0.776099228012361,2.034660375542446,2.5288465238651407,0.6818469365208409,0.7385400373905193
3,643
Antigen processing and presentation of peptide antigen
8
16
2.910407
0.00361
Q9UIQ6,P30101,P30511,Q6P179,O15533,P10321,P27797,Q9NZ08
Processes and pathways
GO Biological process
msigdb_gobp
230,352,6,103,329,48,539,127
2906,329,1139,579,48,1401,539,352,6,1255,829,103,1466,127,230,873
-0.6452882514774274,1.2832942009953483,0.17152746597699287,0.71968985939333,3.135226461008061,0.027862332156932304,0.776099228012361,1.2128654372087189,4.673387267370069,0.11030317972784781,0.4114378359281686,2.3928800946790516,0.007105158915106008,2.239085653646518,1.64289728589414,0.3917410017874763
3,643
Nucleobase containing compound transmembrane transporter activity
10
18
2.896063
0.003779
Q9BSK2,Q9HC21,P51991,P12235,Q86VD7,P41440,Q8TB61,Q6KCM7,Q9H2D1,O00400
Functions
GO Molecular function
msigdb_gomf
327,619,738,581,177,213,410,701,286,123
1395,123,1176,779,1581,581,904,213,738,701,1269,177,1233,410,1127,327,286,619
0.027862332156932304,2.239085653646518,0.15117635458958095,0.4506749437853009,-0.0765234222627171,0.71968985939333,0.3521891223123161,1.692943464578411,0.5091440599781275,0.5671569209643074,0.11030317972784781,1.9223823204371768,0.13076838476814698,1.0700404706148139,0.1918220918189678,1.3008013122061457,1.4566081122737937,0.6818469365208409
3,643
Liposaccharide metabolic process
14
22
2.893088
0.003815
O60512,Q8NBX0,P04062,P17900,P04066,Q969N2,Q96S52,P06280,Q5H8A4,Q16739,Q16880,Q92643,Q9NWW5,O43292
Processes and pathways
GO Biological process
msigdb_gobp
253,33,449,516,426,586,234,549,207,282,246,187,252,373
373,253,2801,449,426,549,1356,3508,1886,516,3049,282,246,207,33,187,586,234,1165,252,3210,649
1.1417856605713883,1.5756684289722063,-0.5998800653389513,0.9611422765478006,1.0157859516403132,0.7573430676997512,0.04856032582182117,-1.2146610216914933,-0.2252475557449799,0.8134720365945656,-0.7139566269396745,1.4566081122737937,1.592529825004484,1.742673161727919,3.476322734521235,1.8575044941143102,0.71968985939333,1.6261440706577892,0.17152746597699287,1.592529825004484,-0.8065769270037231,0.6438120248840904
3,643
Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen
13
32
2.886689
0.003893
Q6UW02,Q12797,O15460,P16435,P07237,Q15800,Q32P28,Q6PK18,P09601,P13674,O60568,P30519,P61457
Functions
GO Molecular function
msigdb_gomf
34,481,194,71,41,487,12,271,175,47,493,93,597
822,875,194,1178,493,706,805,1180,41,175,47,71,93,597,613,481,813,487,1095,12,3099,1956,271,34,2631,1530,936,3296,3274,3472,1172,1391
0.4114378359281686,0.37199154172998977,1.824865383027324,0.15117635458958095,0.850660633843561,0.5478694768628188,0.4310823742970927,0.15117635458958095,3.2870083892475765,1.9385192969684373,3.163027731650402,2.7213338218562386,2.4535901140386045,0.7007922534137548,0.6818469365208409,0.8876671508686171,0.4310823742970927,0.8691865207095048,0.21206060116262693,4.206660830311199,-0.7369966820229626,-0.24674747021415624,1.4908112708908634,3.4629394454457536,-0.5099333245444402,-0.03458833609287247,0.33233340674752826,-0.900446979133231,-0.8768601169890071,-1.1164377040450824,0.17152746597699287,0.04856032582182117
3,643
Macromolecule transmembrane transporter activity
12
15
2.881858
0.003953
O60830,O00189,Q99595,Q07820,P49755,P51991,Q15388,P61619,O96008,Q9Y584,Q9UGP8,Q9NS69
Functions
GO Molecular function
msigdb_gomf
0,695,2,553,225,738,201,363,697,308,221,63
695,754,0,1106,697,225,738,2611,363,553,201,2,63,221,308
0.5671569209643074,0.4897054676751104,5.89350676912575,0.1918220918189678,0.5671569209643074,1.64289728589414,0.5091440599781275,-0.5099333245444402,1.1774078138827289,0.7573430676997512,1.8084952079083476,5.347123193165582,2.837587540785622,1.659614804060893,1.3704358233118867
3,643
Protein insertion into membrane
13
32
2.879261
0.003986
Q9Y5J9,Q15070,P61619,Q15629,Q9Y5J7,Q8N4V1,Q9Y512,Q9Y584,Q8N8Q8,Q96A33,Q8N766,Q9NPA0,Q9NS69
Processes and pathways
GO Biological process
msigdb_gobp
392,200,363,112,433,274,575,308,285,188,349,391,63
753,2357,1026,1484,1106,2361,3188,3312,1631,363,1332,200,112,1896,833,585,274,349,285,965,188,391,63,2077,1349,1436,575,308,751,433,392,1020
0.4897054676751104,-0.42111741427401633,0.25237072765834473,-0.013711595274741894,0.1918220918189678,-0.42111741427401633,-0.8065769270037231,-0.9241144775154201,-0.09758260109774661,1.1774078138827289,0.06919953703395551,1.8084952079083476,2.3470478270665613,-0.2252475557449799,0.4114378359281686,0.71968985939333,1.473728476771492,1.2305331089305223,1.4566081122737937,0.31242405485919195,1.8575044941143102,1.1239123190922105,2.837587540785622,-0.28994201948861137,0.06919953703395551,0.027862332156932304,0.7385400373905193,1.3704358233118867,0.5091440599781275,1.0157859516403132,1.1239123190922105,0.2724430641772754
3,643
Protein exit from endoplasmic reticulum
9
26
2.876418
0.004022
Q8TCT9,P51572,Q9UBV2,P49257,Q9BVK6,O15260,P14625,Q9BUN8,Q13438
Processes and pathways
GO Biological process
msigdb_gobp
364,397,143,238,212,52,184,122,91
755,52,184,238,397,2552,1034,2772,739,91,1420,836,3505,364,1815,1817,1903,122,212,415,995,1078,143,2080,2472,873
0.4897054676751104,3.0230894408053492,1.8900097097013104,1.6093549777202447,1.105997161876891,-0.48762464822389984,0.25237072765834473,-0.5772854996002308,0.5091440599781275,2.483776090582276,0.027862332156932304,0.4114378359281686,-1.1899723271023945,1.1774078138827289,-0.18244015934691968,-0.18244015934691968,-0.2252475557449799,2.254597454452404,1.7095549611048153,1.0519984666463416,0.29246072303462184,0.23224335926748166,2.1296580535061174,-0.28994201948861137,-0.44321720897869366,0.3917410017874763
3,643
Ceramide metabolic process
12
22
2.872232
0.004076
O60512,P27544,Q8NCC3,P04062,P17900,P06280,O95470,Q16739,Q16880,Q96G23,Q9NWW5,Q9NRA0
Processes and pathways
GO Biological process
msigdb_gobp
253,5,358,449,516,549,209,282,246,55,252,257
611,1879,253,209,449,549,1356,3508,516,5,2259,3049,3358,282,246,1896,358,55,1165,257,252,1130
0.6818469365208409,-0.2252475557449799,1.5756684289722063,1.7095549611048153,0.9611422765478006,0.7573430676997512,0.04856032582182117,-1.2146610216914933,0.8134720365945656,4.73149126850177,-0.37712313988404206,-0.7139566269396745,-0.9716940090710073,1.4566081122737937,1.592529825004484,-0.2252475557449799,1.1951570795527422,2.980646976640566,0.17152746597699287,1.5756684289722063,1.592529825004484,0.1918220918189678
3,643
Wormian bones
6
18
2.86985
0.004107
O75718,O95831,P07237,Q96AY3,Q32P28,O75844
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
99,195,41,75,12,217
822,99,217,195,826,41,3449,2667,1033,2559,263,2505,12,1334,1461,75,2789,502
0.4114378359281686,2.423291779810149,1.659614804060893,1.824865383027324,0.4114378359281686,3.2870083892475765,-1.092100830903645,-0.5323126699925248,0.25237072765834473,-0.48762464822389984,1.5418361654019872,-0.465386116003162,4.206660830311199,0.06919953703395551,0.007105158915106008,2.633054429019238,-0.5772854996002308,0.850660633843561
3,643
Outer membrane
40
101
2.868863
0.00412
Q13505,Q8IVP5,Q9HCL2,P45880,O00165,Q99720,Q9Y277,Q9Y6C9,P50402,Q96RL7,Q8N2A8,Q9NX63,Q5XKP0,P21796,Q07820,Q8WY22,Q99623,Q9Y3D6,Q9BUK6,O75323,O43169,P09601,Q9BVC6,Q9Y512,Q8N4H5,Q16891,Q9NS69,O96008,Q9NP58,Q8IWB1,Q15388,Q8WWV3,Q9GZY8,Q9NZ45,Q9UKU0,Q9NZJ7,P57105,P30536,O00264,Q96TC7
Localization
GO Cellular component
msigdb_gocc
519,645,3,261,382,656,661,266,396,532,19,544,670,278,553,36,167,173,45,547,174,175,305,575,56,700,63,697,447,68,201,460,220,229,96,492,232,106,236,380
382,236,1249,3640,174,847,3152,547,1695,1106,999,2480,697,1621,3486,2604,175,2852,2486,278,106,1887,2958,2720,1091,1521,261,396,709,1257,2675,232,3414,553,2618,519,1118,201,2624,3382,700,1896,1852,670,763,1854,1010,1155,645,68,1760,1643,963,19,56,1645,3141,2012,460,1603,36,2063,3455,2066,1041,532,380,1772,167,656,45,1966,305,1469,1568,2345,220,1915,3,447,2461,1973,1047,63,894,1472,1278,945,544,1130,229,492,3346,1280,2898,96,661,3541,173,575,266
1.1239123190922105,1.6093549777202447,0.11030317972784781,-4.459844000520055,1.9385192969684373,0.3917410017874763,-0.7833062289105431,0.7573430676997512,-0.13988634815318823,0.1918220918189678,0.2724430641772754,-0.465386116003162,0.5671569209643074,-0.09758260109774661,-1.1653727114302805,-0.5099333245444402,1.9385192969684373,-0.6225474635721432,-0.465386116003162,1.4566081122737937,2.377631431346862,-0.2252475557449799,-0.6681029929832263,-0.5547632158192415,0.21206060116262693,-0.03458833609287247,1.5418361654019872,1.105997161876891,0.5478694768628188,0.11030317972784781,-0.5323126699925248,1.6261440706577892,-1.0436847151728275,0.7573430676997512,-0.5099333245444402,0.8134720365945656,0.1918220918189678,1.8084952079083476,-0.5099333245444402,-0.9956073764657654,0.5671569209643074,-0.2252475557449799,-0.2038119362780547,0.6055828069993638,0.4897054676751104,-0.2038119362780547,0.2724430641772754,0.17152746597699287,0.6438120248840904,2.794183911350097,-0.16113177748554827,-0.09758260109774661,0.31242405485919195,3.906629108755367,2.9664513233824246,-0.09758260109774661,-0.7601130162085916,-0.2683121372291175,0.9428400929877672,-0.0765234222627171,3.355107227105292,-0.28994201948861137,-1.092100830903645,-0.28994201948861137,0.25237072765834473,0.7948087934495096,1.1417856605713883,-0.16113177748554827,1.9706953778300438,0.6247218507870246,3.204557850940264,-0.24674747021415624,1.3877470096535027,0.007105158915106008,-0.055525473592154824,-0.39908622494449625,1.659614804060893,-0.2252475557449799,5.227283322630259,0.9794004819604001,-0.44321720897869366,-0.24674747021415624,0.25237072765834473,2.837587540785622,0.37199154172998977,0.007105158915106008,0.11030317972784781,0.33233340674752826,0.776099228012361,0.1918220918189678,1.64289728589414,0.8691865207095048,-0.947863266551478,0.11030317972784781,-0.6225474635721432,2.4535901140386045,0.6247218507870246,-1.2643087218937006,1.9546235974626718,0.7385400373905193,1.5248649233353988
3,643
Muscle abnormality related to mitochondrial dysfunction
22
42
2.856891
0.004278
Q9UBX3,O75380,Q96CU9,P03886,O75648,O75306,O96000,Q9BUK6,O43676,Q9Y6M9,O75489,P12235,Q8IUX1,Q7LG56,Q9Y2R0,P00403,Q96RR1,Q8N183,O75251,O00217,P56556,Q86Y39
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
144,650,413,277,536,535,664,45,50,183,696,581,865,864,86,87,603,602,366,734,624,497
734,1875,50,847,366,535,650,696,536,664,1885,87,1000,277,953,581,3080,2605,1521,3129,2045,1221,624,1896,864,497,865,602,1309,1961,413,603,2235,45,1017,2405,1508,144,86,1923,1925,183
0.5091440599781275,-0.2252475557449799,3.107332731050088,0.3917410017874763,1.1596174162013977,0.776099228012361,0.6247218507870246,0.5671569209643074,0.776099228012361,0.6055828069993638,-0.2252475557449799,2.5138506890054337,0.2724430641772754,1.4566081122737937,0.31242405485919195,0.71968985939333,-0.7369966820229626,-0.5099333245444402,-0.03458833609287247,-0.7601130162085916,-0.28994201948861137,0.13076838476814698,0.6628536231131278,-0.2252475557449799,0.3917410017874763,0.850660633843561,0.3917410017874763,0.7007922534137548,0.08978035873173802,-0.24674747021415624,1.0519984666463416,0.7007922534137548,-0.3552276637336356,3.204557850940264,0.2724430641772754,-0.42111741427401633,-0.013711595274741894,2.1296580535061174,2.5288465238651407,-0.2252475557449799,-0.2252475557449799,1.9062125107768622
3,643
Calnexin calreticulin cycle
9
10
2.851723
0.004348
P14314,P30101,Q9UKV5,Q9UBV2,Q9NYU2,P27824,Q13438,O60858,Q14697
Processes and pathways
Reactome Pathways
msigdb_reactome
324,352,169,143,306,118,91,60,445
60,324,539,118,352,91,445,306,143,169
2.866397368803325,1.3008013122061457,0.776099228012361,2.285531889164803,1.2128654372087189,2.483776090582276,0.9794004819604001,1.3877470096535027,2.1296580535061174,1.9706953778300438
3,643
Protein transmembrane transporter activity
7
14
2.849963
0.004372
O60830,Q99595,P49755,Q15388,Q9Y584,Q9UGP8,Q9NS69
Functions
GO Molecular function
msigdb_gomf
0,2,225,201,308,221,63
695,754,0,1106,697,225,2611,363,553,201,2,63,221,308
0.5671569209643074,0.4897054676751104,5.89350676912575,0.1918220918189678,0.5671569209643074,1.64289728589414,-0.5099333245444402,1.1774078138827289,0.7573430676997512,1.8084952079083476,5.347123193165582,2.837587540785622,1.659614804060893,1.3704358233118867
3,643
Organic anion transport
31
56
2.840659
0.004502
Q15041,P30825,P11166,Q9UBX3,Q8TB61,P53985,Q9H2D1,P14174,O43808,Q9Y619,Q14728,Q86VD7,P55011,Q6KCM7,O60831,Q9Y6M7,P04920,Q08722,P12235,Q02978,Q7L0J3,P41440,Q9HC21,Q9NZJ7,P07602,P04083,Q15042,Q01650,P28288,O14745,O00400
Processes and pathways
GO Biological process
msigdb_gobp
915,771,514,144,410,409,286,150,779,694,814,177,678,701,434,846,450,830,581,79,863,213,619,492,231,484,741,376,759,876,123
123,876,2905,1176,779,434,1733,1883,1580,484,450,1581,1445,231,1400,2852,514,581,904,150,759,771,2318,213,1491,409,678,1187,376,79,830,814,915,741,1301,701,1269,3504,863,177,1233,410,2180,2583,3566,1127,1014,286,1313,619,3210,492,144,1434,694,846
2.239085653646518,0.37199154172998977,-0.6452882514774274,0.15117635458958095,0.4506749437853009,0.99761495810321,-0.16113177748554827,-0.2252475557449799,-0.0765234222627171,0.8691865207095048,0.9611422765478006,-0.0765234222627171,0.007105158915106008,1.6261440706577892,0.027862332156932304,-0.6225474635721432,0.8134720365945656,0.71968985939333,0.3521891223123161,2.06645172244257,0.4897054676751104,0.4702158680735321,-0.39908622494449625,1.692943464578411,-0.013711595274741894,1.0700404706148139,0.5863945968863824,0.15117635458958095,1.1417856605713883,2.5885562139486704,0.4114378359281686,0.4310823742970927,0.3521891223123161,0.5091440599781275,0.08978035873173802,0.5671569209643074,0.11030317972784781,-1.1899723271023945,0.3917410017874763,1.9223823204371768,0.13076838476814698,1.0700404706148139,-0.333399306791712,-0.48762464822389984,-1.390041774081608,0.1918220918189678,0.2724430641772754,1.4566081122737937,0.08978035873173802,0.6818469365208409,-0.8065769270037231,0.8691865207095048,2.1296580535061174,0.027862332156932304,0.5863945968863824,0.4114378359281686
3,643
SLC superfamily of solute carriers
24
55
2.834988
0.004583
P11166,Q9Y6C9,Q9UBX3,Q8TB61,P53985,Q9H2D1,O43772,Q9Y619,Q8NEW0,Q86VD7,P55011,Q9BSK2,P04920,P12235,Q02978,P41440,Q96H78,Q9HC21,Q70HW3,Q9NZJ7,Q9H0U3,Q8N1S5,Q01650,O00400
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
514,266,144,410,409,286,663,694,49,177,678,327,450,581,79,213,216,619,357,492,491,247,376,123
123,663,779,1733,1028,1580,450,1581,1400,514,581,904,771,213,1491,409,678,2222,376,79,1893,1301,701,3439,3513,1269,3504,357,863,177,1601,247,49,410,2179,216,2583,3566,1127,1014,327,491,286,941,1313,942,619,492,144,1434,2899,694,1287,266,846
2.239085653646518,0.6055828069993638,0.4506749437853009,-0.16113177748554827,0.25237072765834473,-0.0765234222627171,0.9611422765478006,-0.0765234222627171,0.027862332156932304,0.8134720365945656,0.71968985939333,0.3521891223123161,0.4702158680735321,1.692943464578411,-0.013711595274741894,1.0700404706148139,0.5863945968863824,-0.3552276637336356,1.1417856605713883,2.5885562139486704,-0.2252475557449799,0.08978035873173802,0.5671569209643074,-1.0678500734626066,-1.2146610216914933,0.11030317972784781,-1.1899723271023945,1.1951570795527422,0.3917410017874763,1.9223823204371768,-0.0765234222627171,1.592529825004484,3.12129119884825,1.0700404706148139,-0.333399306791712,1.6762968043598454,-0.48762464822389984,-1.390041774081608,0.1918220918189678,0.2724430641772754,1.3008013122061457,0.8691865207095048,1.4566081122737937,0.33233340674752826,0.08978035873173802,0.33233340674752826,0.6818469365208409,0.8691865207095048,2.1296580535061174,0.027862332156932304,-0.6225474635721432,0.5863945968863824,0.11030317972784781,1.5248649233353988,0.4114378359281686
3,643
Mitochondrial complex iv assembly
9
16
2.834488
0.00459
Q9Y241,P13073,Q8N8Q8,O43819,P20674,Q9Y2R0,Q7KZN9,P00403,P14406
Processes and pathways
WikiPathways
msigdb_wp
593,515,285,333,651,86,378,87,28
1875,333,1885,87,1583,756,1252,515,28,1218,651,378,285,1683,593,86
-0.2252475557449799,1.2657472734377568,-0.2252475557449799,2.5138506890054337,-0.0765234222627171,0.4897054676751104,0.11030317972784781,0.8134720365945656,3.5429255537908872,0.13076838476814698,0.6247218507870246,1.1417856605713883,1.4566081122737937,-0.11870343366061006,0.71968985939333,2.5288465238651407
3,643
Atp synthesis coupled electron transport
24
44
2.833268
0.004607
O75438,P13073,O14949,P20674,O75380,P03886,O75306,O96000,O95139,P47985,O43676,Q9Y6M9,O75489,Q9UDW1,O43674,Q9H3K2,O95168,P00403,O95167,O14548,O75251,O00217,P56556,Q7KZN9
Processes and pathways
GO Biological process
msigdb_gobp
768,515,137,651,650,277,535,664,548,808,50,183,696,198,321,468,470,87,341,717,366,734,624,378
734,1875,717,137,321,50,2358,366,535,650,768,696,548,341,470,806,1515,2155,664,1885,87,277,953,1251,1357,2363,1252,515,1056,1218,3080,651,2605,1405,808,3129,624,1498,2280,378,3567,468,198,183
0.5091440599781275,-0.2252475557449799,0.5285319592869173,2.1453820763492155,1.3008013122061457,3.107332731050088,-0.42111741427401633,1.1596174162013977,0.776099228012361,0.6247218507870246,0.4702158680735321,0.5671569209643074,0.7573430676997512,1.2481603149029503,0.9061027846832771,0.4310823742970927,-0.03458833609287247,-0.333399306791712,0.6055828069993638,-0.2252475557449799,2.5138506890054337,1.4566081122737937,0.31242405485919195,0.11030317972784781,0.04856032582182117,-0.42111741427401633,0.11030317972784781,0.8134720365945656,0.23224335926748166,0.13076838476814698,-0.7369966820229626,0.6247218507870246,-0.5099333245444402,0.027862332156932304,0.4310823742970927,-0.7601130162085916,0.6628536231131278,-0.013711595274741894,-0.37712313988404206,1.1417856605713883,-1.390041774081608,0.9244936801618757,1.824865383027324,1.9062125107768622
3,643
Cytochrome complex
10
19
2.824115
0.004741
Q9UDW1,P13073,O14949,P47985,P20674,Q7KZN9,P00403,O14548,P14406,P22695
Localization
GO Cellular component
msigdb_gocc
198,515,137,808,651,378,87,717,28,563
1875,717,137,1885,87,1357,1583,1252,515,28,1056,1218,651,563,881,808,378,198,1436
-0.2252475557449799,0.5285319592869173,2.1453820763492155,-0.2252475557449799,2.5138506890054337,0.04856032582182117,-0.0765234222627171,0.11030317972784781,0.8134720365945656,3.5429255537908872,0.23224335926748166,0.13076838476814698,0.6247218507870246,0.7385400373905193,0.37199154172998977,0.4310823742970927,1.1417856605713883,1.824865383027324,0.027862332156932304
3,643
Sarcoplasm
8
20
2.805511
0.005024
Q12797,O00165,P16615,O43852,Q9BVC6,Q13555,P14625,P27797
Localization
GO Cellular component
msigdb_gocc
481,382,267,16,305,153,184,539
382,16,546,184,267,539,3311,2160,2216,1257,1525,1362,481,1365,153,1118,2287,1603,305,2592
1.1239123190922105,4.095354306912875,0.7573430676997512,1.8900097097013104,1.5078566888617457,0.776099228012361,-0.9241144775154201,-0.333399306791712,-0.3552276637336356,0.11030317972784781,-0.03458833609287247,0.04856032582182117,0.8876671508686171,0.04856032582182117,2.06645172244257,0.1918220918189678,-0.37712313988404206,-0.0765234222627171,1.3877470096535027,-0.48762464822389984
3,643
External encapsulating structure organization
11
28
2.802658
0.005068
O75718,P07942,P05067,Q13162,Q96AY3,P13674,Q92791,Q96HE7,P41440,O60568,P39210
Processes and pathways
GO Biological process
msigdb_gobp
99,196,385,72,75,47,113,411,213,493,505
493,2803,1290,99,1213,385,1445,196,580,47,1551,1840,505,213,909,72,3291,762,2340,2577,919,113,75,411,3143,1777,3066,2592
0.850660633843561,-0.5998800653389513,0.08978035873173802,2.423291779810149,0.13076838476814698,1.1239123190922105,0.007105158915106008,1.824865383027324,0.71968985939333,3.163027731650402,-0.055525473592154824,-0.2038119362780547,0.832089227524965,1.692943464578411,0.3521891223123161,2.692012537294508,-0.900446979133231,0.4897054676751104,-0.39908622494449625,-0.48762464822389984,0.3521891223123161,2.3470478270665613,2.633054429019238,1.0700404706148139,-0.7601130162085916,-0.16113177748554827,-0.7139566269396745,-0.48762464822389984
3,643
Protein folding in endoplasmic reticulum
8
10
2.802513
0.005071
Q8IXB1,P30101,Q13217,P07237,Q86YB8,Q96HE7,P27824,P14625
Processes and pathways
GO Biological process
msigdb_gobp
129,352,166,41,530,411,118,184
41,184,539,118,352,166,530,129,411,1785
3.2870083892475765,1.8900097097013104,0.776099228012361,2.285531889164803,1.2128654372087189,1.9706953778300438,0.7948087934495096,2.223543950079106,1.0700404706148139,-0.16113177748554827
3,643
Carbohydrate derivative transport
13
23
2.791408
0.005248
Q9HC21,Q8WTV0,Q9NZJ7,P07602,P12235,Q86VD7,P61916,P41440,Q8TB61,Q6KCM7,Q96AA3,O43808,O00400
Processes and pathways
GO Biological process
msigdb_gobp
619,420,492,231,581,177,466,213,410,701,250,779,123
1395,123,1176,779,1581,231,581,904,213,466,830,701,1269,177,1233,410,2180,420,250,1127,619,3210,492
0.027862332156932304,2.239085653646518,0.15117635458958095,0.4506749437853009,-0.0765234222627171,1.6261440706577892,0.71968985939333,0.3521891223123161,1.692943464578411,0.9244936801618757,0.4114378359281686,0.5671569209643074,0.11030317972784781,1.9223823204371768,0.13076838476814698,1.0700404706148139,-0.333399306791712,1.0339137070490352,1.592529825004484,0.1918220918189678,0.6818469365208409,-0.8065769270037231,0.8691865207095048
3,643
Abnormal activity of mitochondrial respiratory chain
27
58
2.781313
0.005414
P13073,Q9UBX3,P20674,O75380,P30084,P21912,Q96CU9,P03886,O75648,O75306,O96000,O43676,Q9Y584,Q9Y6M9,Q3ZCQ8,O75489,P08559,Q9Y2R0,Q8N183,Q96EY7,Q70HW3,O75251,O00217,P56556,Q7KZN9,Q86Y39,Q9H0R6
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
515,144,651,650,528,538,413,277,536,535,664,50,308,183,566,696,451,86,602,747,357,366,734,624,378,497,510
734,1875,50,2358,366,535,650,696,536,2155,664,277,451,756,515,3080,651,538,2605,528,1405,1521,1939,3129,1328,2045,624,1892,3201,2280,566,834,2509,357,378,497,865,602,1309,1861,413,747,1240,2235,510,993,1017,2405,1508,1349,3302,144,897,86,1437,308,2536,183
0.5091440599781275,-0.2252475557449799,3.107332731050088,-0.42111741427401633,1.1596174162013977,0.776099228012361,0.6247218507870246,0.5671569209643074,0.776099228012361,-0.333399306791712,0.6055828069993638,1.4566081122737937,0.9611422765478006,0.4897054676751104,0.8134720365945656,-0.7369966820229626,0.6247218507870246,0.776099228012361,-0.5099333245444402,0.7948087934495096,0.027862332156932304,-0.03458833609287247,-0.24674747021415624,-0.7601130162085916,0.06919953703395551,-0.28994201948861137,0.6628536231131278,-0.2252475557449799,-0.8065769270037231,-0.37712313988404206,0.7385400373905193,0.4114378359281686,-0.465386116003162,1.1951570795527422,1.1417856605713883,0.850660633843561,0.3917410017874763,0.7007922534137548,0.08978035873173802,-0.2038119362780547,1.0519984666463416,0.5091440599781275,0.13076838476814698,-0.3552276637336356,0.832089227524965,0.29246072303462184,0.2724430641772754,-0.42111741427401633,-0.013711595274741894,0.06919953703395551,-0.900446979133231,2.1296580535061174,0.37199154172998977,2.5288465238651407,0.027862332156932304,1.3704358233118867,-0.465386116003162,1.9062125107768622
3,643
oxidoreductase
24
50
2.77904
0.005452
Q15067,O43396,O14949,Q86YB8,O75380,Q96HE7,O75306,O43169,O15254,O43676,Q9Y6M9,Q9Y320,Q9BUP3,O95831,O43674,P16435,Q9Y6N5,O95168,P00403,Q13630,Q8N0U8,P56556,Q86Y39,P23368
Functions
Panther Protein class
panther_protein_class
387,383,137,530,650,411,535,174,302,50,183,448,590,195,321,71,205,470,87,475,498,624,497,119
734,1875,137,302,174,383,321,50,2358,535,650,470,806,1515,195,664,87,953,2662,2363,3334,71,3081,119,2915,3431,2607,760,3129,624,1749,475,387,2625,1498,2280,2927,1231,497,530,498,1158,411,3258,590,2347,2405,448,183,205
0.5091440599781275,-0.2252475557449799,2.1453820763492155,1.3877470096535027,1.9385192969684373,1.1239123190922105,1.3008013122061457,3.107332731050088,-0.42111741427401633,0.776099228012361,0.6247218507870246,0.9061027846832771,0.4310823742970927,-0.03458833609287247,1.824865383027324,0.6055828069993638,2.5138506890054337,0.31242405485919195,-0.5323126699925248,-0.42111741427401633,-0.947863266551478,2.7213338218562386,-0.7369966820229626,2.2700794880847806,-0.6452882514774274,-1.0678500734626066,-0.5099333245444402,0.4897054676751104,-0.7601130162085916,0.6628536231131278,-0.16113177748554827,0.9061027846832771,1.1239123190922105,-0.5099333245444402,-0.013711595274741894,-0.37712313988404206,-0.6452882514774274,0.13076838476814698,0.850660633843561,0.7948087934495096,0.850660633843561,0.17152746597699287,1.0700404706148139,-0.8533532449353657,0.71968985939333,-0.39908622494449625,-0.42111741427401633,0.9794004819604001,1.9062125107768622,1.7756527899161132
3,643
Oxidoreductase activity acting on a sulfur group of donors
16
30
2.771541
0.005579
Q8IXB1,Q9Y320,P30101,Q15084,O43396,P07237,Q9H3N1,Q14554,Q9Y6N5,O95881,O43819,Q9UHG3,Q96HE7,Q8NBM8,P13667,Q96JJ7
Functions
GO Molecular function
msigdb_gomf
129,448,352,419,383,41,297,108,205,237,333,84,411,248,443,350
383,333,3485,237,2255,3351,41,2363,443,1058,352,3431,3417,3599,108,419,2056,1231,989,3440,530,129,248,411,350,1606,297,84,448,205
1.1239123190922105,1.2657472734377568,-1.1653727114302805,1.6093549777202447,-0.37712313988404206,-0.9716940090710073,3.2870083892475765,-0.42111741427401633,0.9794004819604001,0.23224335926748166,1.2128654372087189,-1.0678500734626066,-1.0436847151728275,-1.7284029204584987,2.377631431346862,1.0339137070490352,-0.28994201948861137,0.13076838476814698,0.29246072303462184,-1.0678500734626066,0.7948087934495096,2.223543950079106,1.592529825004484,1.0700404706148139,1.2305331089305223,-0.0765234222627171,1.4050196301598754,2.5587558625495044,0.9794004819604001,1.7756527899161132
3,643
Protein n linked glycosylation
11
23
2.770168
0.005603
Q9BT22,Q13724,P04843,Q9H0U3,Q93063,P04844,Q8TCJ2,Q9NYU2,P46977,Q96AA3,Q86YN1
Processes and pathways
GO Biological process
msigdb_gobp
161,356,384,491,359,395,336,306,152,250,155
2602,848,902,384,395,1551,1057,1030,152,3544,2223,356,486,155,336,359,250,161,633,491,942,306,2080
-0.5099333245444402,0.3917410017874763,0.3521891223123161,1.1239123190922105,1.105997161876891,-0.055525473592154824,0.23224335926748166,0.25237072765834473,2.06645172244257,-1.2892692909305767,-0.3552276637336356,1.1951570795527422,0.8691865207095048,2.050571853401436,1.2657472734377568,1.1951570795527422,1.592529825004484,2.018717139797755,0.6628536231131278,0.8691865207095048,0.33233340674752826,1.3877470096535027,-0.28994201948861137
3,643
Peptide hormone metabolism
6
18
2.759761
0.005784
O00471,P67812,Q15005,Q8NEW0,Q96HE7,O75787
Processes and pathways
Reactome Pathways
msigdb_reactome
351,128,269,49,411,254
351,1618,254,3128,1181,1627,1407,128,269,530,2577,49,838,1766,411,1768,1539,1476
1.2128654372087189,-0.09758260109774661,1.5756684289722063,-0.7601130162085916,0.15117635458958095,-0.09758260109774661,0.027862332156932304,2.223543950079106,1.4908112708908634,0.7948087934495096,-0.48762464822389984,3.12129119884825,0.4114378359281686,-0.16113177748554827,1.0700404706148139,-0.16113177748554827,-0.03458833609287247,0.007105158915106008
3,643
Protein o linked glycosylation
13
18
2.756957
0.005834
O43505,Q02809,O15294,Q9H488,Q8NAT1,Q86SF2,Q10472,Q9Y2G5,Q6ZXV5,Q8N4A0,O60568,Q7Z4H8,Q9H9S5
Processes and pathways
GO Biological process
msigdb_gobp
662,613,328,674,46,765,210,53,214,180,493,283,843
822,328,662,2909,493,2801,902,613,1750,210,214,283,765,180,46,674,843,53
0.4114378359281686,1.2832942009953483,0.6055828069993638,-0.6452882514774274,0.850660633843561,-0.5998800653389513,0.3521891223123161,0.6818469365208409,-0.16113177748554827,1.7095549611048153,1.692943464578411,1.4566081122737937,0.4897054676751104,1.9062125107768622,3.190737263872994,0.6055828069993638,0.4114378359281686,3.0230894408053492
3,643
Type i collagen synthesis in the context of osteogenesis imperfecta
6
13
2.754418
0.00588
O75718,O15460,P07237,Q96AY3,Q32P28,P13674
Processes and pathways
WikiPathways
msigdb_wp
99,194,41,75,12,47
822,194,99,41,47,2667,909,613,12,342,919,75,2592
0.4114378359281686,1.824865383027324,2.423291779810149,3.2870083892475765,3.163027731650402,-0.5323126699925248,0.3521891223123161,0.6818469365208409,4.206660830311199,1.2481603149029503,0.3521891223123161,2.633054429019238,-0.48762464822389984
3,643
Protease
27
89
2.753911
0.005889
P67812,P55786,Q9BYT8,Q15005,Q7Z2K6,O14773,Q96RU2,Q5JRX3,Q9NQW7,Q16740,Q9H8M7,Q9UPT9,P28072,Q2T9J0,Q92643,P52888,Q4J6C6,Q92905,Q9H3G5,O75844,Q9UIQ6,P78536,Q6P179,Q8TCT9,P28074,Q99436,Q9NZ08
Functions
Protein Atlas Molecular function
protein_atlas_molecular_function
128,138,141,269,147,25,288,35,38,428,430,307,54,309,187,325,459,77,344,217,230,226,103,364,243,381,127
899,900,25,2246,578,879,217,3530,2989,2990,1442,3159,1663,2663,2483,1401,3336,54,243,3430,3474,1519,1628,3587,955,2493,2263,2551,1803,325,2326,854,979,3004,138,1407,128,226,3288,1330,3398,2441,269,428,309,459,35,723,103,147,1563,2448,1307,3017,1762,364,187,77,2970,1533,731,3256,655,938,288,841,381,3567,1466,866,141,795,344,3614,3324,430,464,591,38,869,2024,127,230,307,1248,1133,2412,620,3243
0.3521891223123161,0.3521891223123161,3.661517338984293,-0.37712313988404206,0.71968985939333,0.37199154172998977,1.659614804060893,-1.2643087218937006,-0.6909922588809689,-0.6909922588809689,0.007105158915106008,-0.7833062289105431,-0.11870343366061006,-0.5323126699925248,-0.465386116003162,0.027862332156932304,-0.947863266551478,2.980646976640566,1.592529825004484,-1.0678500734626066,-1.1408614189622066,-0.03458833609287247,-0.09758260109774661,-1.5701048558026782,0.31242405485919195,-0.465386116003162,-0.37712313988404206,-0.48762464822389984,-0.18244015934691968,1.3008013122061457,-0.39908622494449625,0.3917410017874763,0.29246072303462184,-0.6909922588809689,2.1453820763492155,0.027862332156932304,2.223543950079106,1.64289728589414,-0.900446979133231,0.06919953703395551,-1.019604048841438,-0.44321720897869366,1.4908112708908634,1.0157859516403132,1.3530858670526362,0.9428400929877672,3.4495350664729076,0.5285319592869173,2.3928800946790516,2.0981172248521958,-0.055525473592154824,-0.44321720897869366,0.08978035873173802,-0.6909922588809689,-0.16113177748554827,1.1774078138827289,1.8575044941143102,2.6034158117050517,-0.6681029929832263,-0.03458833609287247,0.5285319592869173,-0.8533532449353657,0.6247218507870246,0.33233340674752826,1.4394499815716364,0.4114378359281686,1.1417856605713883,-1.390041774081608,0.007105158915106008,0.3917410017874763,2.1296580535061174,0.4506749437853009,1.2481603149029503,-1.9455372097525145,-0.9241144775154201,1.0157859516403132,0.9428400929877672,0.71968985939333,3.314313786509081,0.3917410017874763,-0.2683121372291175,2.239085653646518,1.64289728589414,1.3877470096535027,0.13076838476814698,0.1918220918189678,-0.42111741427401633,0.6818469365208409,-0.829925724951396
3,643
Chaperone J-domain superfamily [IPR036869]
7
20
2.744354
0.006063
Q8IXB1,Q9Y2G8,Q96KC8,O14976,Q13217,Q99543,Q9UGP8
Sequence
InterPro Superfamily
interpro_homologous_superfamily
129,354,228,320,166,571,221
320,1578,1694,1290,1324,1404,1587,166,2225,129,920,1040,228,571,2453,1278,1315,660,221,354
1.3008013122061457,-0.0765234222627171,-0.13988634815318823,0.08978035873173802,0.06919953703395551,0.027862332156932304,-0.0765234222627171,1.9706953778300438,-0.3552276637336356,2.223543950079106,0.3521891223123161,0.25237072765834473,1.64289728589414,0.7385400373905193,-0.44321720897869366,0.11030317972784781,0.08978035873173802,0.6247218507870246,1.659614804060893,1.2128654372087189
3,643
DnaJ domain [IPR001623]
7
20
2.744354
0.006063
Q8IXB1,Q9Y2G8,Q96KC8,O14976,Q13217,Q99543,Q9UGP8
Sequence
InterPro Domain
interpro_domain
129,354,228,320,166,571,221
320,1578,1694,1290,1324,1404,1587,166,2225,129,920,1040,228,571,2453,1278,1315,660,221,354
1.3008013122061457,-0.0765234222627171,-0.13988634815318823,0.08978035873173802,0.06919953703395551,0.027862332156932304,-0.0765234222627171,1.9706953778300438,-0.3552276637336356,2.223543950079106,0.3521891223123161,0.25237072765834473,1.64289728589414,0.7385400373905193,-0.44321720897869366,0.11030317972784781,0.08978035873173802,0.6247218507870246,1.659614804060893,1.2128654372087189
3,643
Nadh dehydrogenase activity
16
28
2.74221
0.006103
O75489,O96000,O95831,O43674,O75438,O95139,O75251,O00217,O43676,O75380,Q9Y6M9,O95168,P56556,O95167,P03886,O75306
Functions
GO Molecular function
msigdb_gomf
696,664,195,321,768,548,366,734,50,650,183,470,624,341,277,535
734,1875,321,50,2358,366,535,650,768,696,548,341,470,806,1515,2155,195,664,277,953,3080,2605,3129,624,1498,2280,1349,183
0.5091440599781275,-0.2252475557449799,1.3008013122061457,3.107332731050088,-0.42111741427401633,1.1596174162013977,0.776099228012361,0.6247218507870246,0.4702158680735321,0.5671569209643074,0.7573430676997512,1.2481603149029503,0.9061027846832771,0.4310823742970927,-0.03458833609287247,-0.333399306791712,1.824865383027324,0.6055828069993638,1.4566081122737937,0.31242405485919195,-0.7369966820229626,-0.5099333245444402,-0.7601130162085916,0.6628536231131278,-0.013711595274741894,-0.37712313988404206,0.06919953703395551,1.9062125107768622
3,643
Antigen processing and presentation of peptide antigen via mhc class i
8
14
2.734611
0.006245
Q9UIQ6,P30101,P30511,Q6P179,O15533,P10321,P27797,Q9NZ08
Processes and pathways
GO Biological process
msigdb_gobp
230,352,6,103,329,48,539,127
2906,329,1139,579,48,1401,539,352,6,829,103,127,230,873
-0.6452882514774274,1.2832942009953483,0.17152746597699287,0.71968985939333,3.135226461008061,0.027862332156932304,0.776099228012361,1.2128654372087189,4.673387267370069,0.4114378359281686,2.3928800946790516,2.239085653646518,1.64289728589414,0.3917410017874763
3,643
metalloprotease
12
27
2.731493
0.006305
Q9UIQ6,Q9NQH7,Q5JRX3,P52888,Q6P179,P55786,Q9BYT8,O43847,Q7Z2K6,O75844,Q9NZ08,P22695
Functions
Panther Protein class
panther_protein_class
230,591,35,325,103,138,141,578,147,217,127,563
578,879,217,1442,3606,2483,1401,563,3430,881,955,325,854,138,1093,35,103,147,938,841,866,141,591,2024,127,230,620
0.71968985939333,0.37199154172998977,1.659614804060893,0.007105158915106008,-1.8360748989715658,-0.465386116003162,0.027862332156932304,0.7385400373905193,-1.0678500734626066,0.37199154172998977,0.31242405485919195,1.3008013122061457,0.3917410017874763,2.1453820763492155,0.21206060116262693,3.4495350664729076,2.3928800946790516,2.0981172248521958,0.33233340674752826,0.4114378359281686,0.3917410017874763,2.1296580535061174,0.71968985939333,-0.2683121372291175,2.239085653646518,1.64289728589414,0.6818469365208409
3,643
Nucleotide transport
11
18
2.731081
0.006313
Q9BSK2,Q9HC21,Q08722,P12235,Q86VD7,P41440,Q8TB61,Q6KCM7,Q9H2D1,O43808,O00400
Processes and pathways
GO Biological process
msigdb_gobp
327,619,830,581,177,213,410,701,286,779,123
123,1176,779,1581,581,904,213,830,701,1269,177,1233,410,2180,1127,327,286,619
2.239085653646518,0.15117635458958095,0.4506749437853009,-0.0765234222627171,0.71968985939333,0.3521891223123161,1.692943464578411,0.4114378359281686,0.5671569209643074,0.11030317972784781,1.9223823204371768,0.13076838476814698,1.0700404706148139,-0.333399306791712,0.1918220918189678,1.3008013122061457,1.4566081122737937,0.6818469365208409
3,643
Ubiquitin dependent erad pathway
14
41
2.73057
0.006322
Q8IXB1,O75477,Q9UKV5,P51572,Q8TCJ2,Q9UBV2,Q9UBU6,Q96A33,O94905,P27824,P14625,Q9BUN8,Q13438,O60858
Processes and pathways
GO Biological process
msigdb_gobp
129,322,169,397,336,143,82,188,334,118,184,122,91,60
469,1484,60,322,780,334,2990,707,184,539,118,1736,1631,397,3004,2552,2772,739,3089,91,1227,2278,3098,1193,129,3505,336,1764,1817,188,1903,122,1315,82,143,169,799,2651,3304,2080,2472
0.9061027846832771,-0.013711595274741894,2.866397368803325,1.3008013122061457,0.4506749437853009,1.2657472734377568,-0.6909922588809689,0.5478694768628188,1.8900097097013104,0.776099228012361,2.285531889164803,-0.16113177748554827,-0.09758260109774661,1.105997161876891,-0.6909922588809689,-0.48762464822389984,-0.5772854996002308,0.5091440599781275,-0.7369966820229626,2.483776090582276,0.13076838476814698,-0.37712313988404206,-0.7369966820229626,0.15117635458958095,2.223543950079106,-1.1899723271023945,1.2657472734377568,-0.16113177748554827,-0.18244015934691968,1.8575044941143102,-0.2252475557449799,2.254597454452404,0.08978035873173802,2.5587558625495044,2.1296580535061174,1.9706953778300438,0.4506749437853009,-0.5099333245444402,-0.900446979133231,-0.28994201948861137,-0.44321720897869366
3,643
Erad pathway
16
49
2.730049
0.006332
Q8IXB1,O75477,Q9UKV5,Q8TCT9,Q13438,Q8TCJ2,Q9UBV2,Q9UBU6,Q9NYU2,Q96A33,O94905,P27824,P14625,Q9BUN8,Q4ZIN3,O60858
Processes and pathways
GO Biological process
msigdb_gobp
129,322,169,364,91,336,143,82,306,188,334,118,184,122,27,60
3617,469,1484,60,322,780,334,2990,707,184,539,118,1736,1631,397,3004,2552,2772,739,3089,1224,91,1227,2278,27,3098,1193,585,129,836,3505,336,364,1764,1817,188,1903,122,3178,1315,306,82,143,169,799,2651,3304,2080,2472
-2.0288519737109936,0.9061027846832771,-0.013711595274741894,2.866397368803325,1.3008013122061457,0.4506749437853009,1.2657472734377568,-0.6909922588809689,0.5478694768628188,1.8900097097013104,0.776099228012361,2.285531889164803,-0.16113177748554827,-0.09758260109774661,1.105997161876891,-0.6909922588809689,-0.48762464822389984,-0.5772854996002308,0.5091440599781275,-0.7369966820229626,0.13076838476814698,2.483776090582276,0.13076838476814698,-0.37712313988404206,3.569421755662869,-0.7369966820229626,0.15117635458958095,0.71968985939333,2.223543950079106,0.4114378359281686,-1.1899723271023945,1.2657472734377568,1.1774078138827289,-0.16113177748554827,-0.18244015934691968,1.8575044941143102,-0.2252475557449799,2.254597454452404,-0.7833062289105431,0.08978035873173802,1.3877470096535027,2.5587558625495044,2.1296580535061174,1.9706953778300438,0.4506749437853009,-0.5099333245444402,-0.900446979133231,-0.28994201948861137,-0.44321720897869366
3,643
Tetrapyrrole metabolic process
11
24
2.714524
0.006637
O75027,Q9NPF0,P30536,O14678,P09601,O00264,P30519,Q7KZN9,P22830,Q96EY8,Q9NP58
Processes and pathways
GO Biological process
msigdb_gobp
260,524,106,301,175,236,93,378,564,414,447
236,301,260,1697,1985,175,564,93,106,2318,652,1184,2220,2509,378,414,966,447,524,2074,1277,970,3302,1105
1.6093549777202447,1.3877470096535027,1.5418361654019872,-0.13988634815318823,-0.2683121372291175,1.9385192969684373,0.7385400373905193,2.4535901140386045,2.377631431346862,-0.39908622494449625,0.6247218507870246,0.15117635458958095,-0.3552276637336356,-0.465386116003162,1.1417856605713883,1.0519984666463416,0.31242405485919195,0.9794004819604001,0.8134720365945656,-0.28994201948861137,0.11030317972784781,0.31242405485919195,-0.900446979133231,0.21206060116262693
3,643
Vacuolar lumen
24
69
2.712583
0.006676
P17900,Q8NBS9,O14773,P08236,P10253,Q9H7Z7,Q13217,Q9BWS9,P04066,P34059,P06280,Q9UM22,P54802,Q14108,Q8IV08,Q9UMR5,P04062,P61916,P38435,Q9BTY2,Q9NZJ7,P07602,Q8NHP8,P50897
Localization
GO Cellular component
msigdb_gocc
516,402,25,157,537,158,166,40,426,551,549,51,436,444,65,66,449,466,80,90,492,231,233,244
2948,1289,2415,25,1026,1621,449,426,549,1356,770,2952,231,3508,2361,157,537,2663,3509,880,2364,3555,582,1886,516,2544,2769,2547,551,80,3628,1671,1254,244,2609,2674,979,1673,436,2552,2773,466,3134,1594,3196,3049,166,3358,444,3055,65,402,233,1236,1903,1650,1772,1466,1685,90,40,3457,158,2979,492,51,66,2752,1174
-0.6681029929832263,0.08978035873173802,-0.44321720897869366,3.661517338984293,0.25237072765834473,-0.09758260109774661,0.9611422765478006,1.0157859516403132,0.7573430676997512,0.04856032582182117,0.4702158680735321,-0.6681029929832263,1.6261440706577892,-1.2146610216914933,-0.42111741427401633,2.034660375542446,0.776099228012361,-0.5323126699925248,-1.2146610216914933,0.37199154172998977,-0.42111741427401633,-1.3394678563793248,0.71968985939333,-0.2252475557449799,0.8134720365945656,-0.48762464822389984,-0.5772854996002308,-0.48762464822389984,0.7573430676997512,2.5587558625495044,-2.314556559776012,-0.11870343366061006,0.11030317972784781,1.592529825004484,-0.5099333245444402,-0.5323126699925248,0.29246072303462184,-0.11870343366061006,0.99761495810321,-0.48762464822389984,-0.5772854996002308,0.9244936801618757,-0.7601130162085916,-0.0765234222627171,-0.8065769270037231,-0.7139566269396745,1.9706953778300438,-0.9716940090710073,0.9794004819604001,-0.7139566269396745,2.808677111591547,1.0880399570282553,1.6261440706577892,0.13076838476814698,-0.2252475557449799,-0.09758260109774661,-0.16113177748554827,0.007105158915106008,-0.11870343366061006,2.4988272513624805,3.3006721207392853,-1.092100830903645,2.034660375542446,-0.6681029929832263,0.8691865207095048,3.037189084386894,2.808677111591547,-0.5547632158192415,0.17152746597699287
3,643
N glycan biosynthesis
11
20
2.708869
0.006751
O60512,Q9BT22,Q13724,P04843,P04844,Q8TCJ2,O60476,P46977,Q96AA3,Q86YN1,Q14697
Processes and pathways
KEGG Pathways
msigdb_kegg
253,161,356,384,395,336,545,152,250,155,445
545,253,2801,2602,384,395,1551,1057,1736,1030,152,3544,356,445,1951,155,336,250,161,633
0.7573430676997512,1.5756684289722063,-0.5998800653389513,-0.5099333245444402,1.1239123190922105,1.105997161876891,-0.055525473592154824,0.23224335926748166,-0.16113177748554827,0.25237072765834473,2.06645172244257,-1.2892692909305767,1.1951570795527422,0.9794004819604001,-0.24674747021415624,2.050571853401436,1.2657472734377568,1.592529825004484,2.018717139797755,0.6628536231131278
3,643
Abnormal mitochondria in muscle tissue
14
27
2.705298
0.006824
O75489,O96000,Q9Y4W6,O75251,O43676,O75380,Q9Y6M9,P56556,P00403,Q86Y39,Q8N183,Q96CU9,P03886,O75306
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
696,664,620,366,50,650,183,624,87,497,602,413,277,535
734,50,366,535,650,696,664,1885,87,277,953,3080,2605,1405,3129,624,497,865,602,1309,413,2235,1017,2405,1508,620,183
0.5091440599781275,3.107332731050088,1.1596174162013977,0.776099228012361,0.6247218507870246,0.5671569209643074,0.6055828069993638,-0.2252475557449799,2.5138506890054337,1.4566081122737937,0.31242405485919195,-0.7369966820229626,-0.5099333245444402,0.027862332156932304,-0.7601130162085916,0.6628536231131278,0.850660633843561,0.3917410017874763,0.7007922534137548,0.08978035873173802,1.0519984666463416,-0.3552276637336356,0.2724430641772754,-0.42111741427401633,-0.013711595274741894,0.6818469365208409,1.9062125107768622
3,643
Cardiac muscle contraction
12
23
2.700646
0.00692
Q9UDW1,P13073,P16615,O14949,P67936,P47985,P20674,P00403,O14548,P14406,P22695,P31930
Processes and pathways
KEGG Pathways
msigdb_kegg
198,515,267,137,980,808,651,87,717,28,563,881
717,137,1885,87,976,1108,1984,1357,1446,1583,1252,515,28,1056,1218,267,651,563,881,808,2107,980,198
0.5285319592869173,2.1453820763492155,-0.2252475557449799,2.5138506890054337,0.29246072303462184,0.1918220918189678,-0.2683121372291175,0.04856032582182117,0.007105158915106008,-0.0765234222627171,0.11030317972784781,0.8134720365945656,3.5429255537908872,0.23224335926748166,0.13076838476814698,1.5078566888617457,0.6247218507870246,0.7385400373905193,0.37199154172998977,0.4310823742970927,-0.3116375849262432,0.29246072303462184,1.824865383027324
3,643
Organic acid transmembrane transport
16
35
2.693775
0.007065
P23786,O43772,P11166,P31751,Q9Y619,O14678,P50416,P08183,Q9UBX3,Q02978,P41440,Q9H2D1,P53985,O60831,P28288,Q01650
Processes and pathways
GO Biological process
msigdb_gobp
255,663,514,550,694,301,709,303,144,79,213,286,409,434,759,376
301,663,434,1733,1883,1580,1445,303,1400,514,255,759,771,2770,550,1887,2318,213,709,1491,409,376,79,915,1301,1233,2180,2583,3566,1014,286,1313,144,1434,694
1.3877470096535027,0.6055828069993638,0.99761495810321,-0.16113177748554827,-0.2252475557449799,-0.0765234222627171,0.007105158915106008,1.3877470096535027,0.027862332156932304,0.8134720365945656,1.5756684289722063,0.4897054676751104,0.4702158680735321,-0.5772854996002308,0.7573430676997512,-0.2252475557449799,-0.39908622494449625,1.692943464578411,0.5478694768628188,-0.013711595274741894,1.0700404706148139,1.1417856605713883,2.5885562139486704,0.3521891223123161,0.08978035873173802,0.13076838476814698,-0.333399306791712,-0.48762464822389984,-1.390041774081608,0.2724430641772754,1.4566081122737937,0.08978035873173802,2.1296580535061174,0.027862332156932304,0.5863945968863824
3,643
Metalloendopeptidase activity
8
15
2.693151
0.007078
P78536,P52888,Q5JRX3,Q9BYT8,Q92905,O43847,O75844,P22695
Functions
GO Molecular function
msigdb_gomf
226,325,35,141,77,578,217,563
578,879,217,1401,563,955,325,226,1093,35,77,841,866,141,620
0.71968985939333,0.37199154172998977,1.659614804060893,0.027862332156932304,0.7385400373905193,0.31242405485919195,1.3008013122061457,1.64289728589414,0.21206060116262693,3.4495350664729076,2.6034158117050517,0.4114378359281686,0.3917410017874763,2.1296580535061174,0.6818469365208409
3,643
Horizontal nystagmus
7
24
2.692843
0.007085
O95831,P04062,P07602,Q9NSE4,Q9H061,O94905,O14773
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
195,449,231,182,148,334,25
2982,1249,25,1353,847,334,195,1000,449,231,756,1586,1800,1522,1328,1033,2428,2830,1199,1163,148,182,492,2651
-0.6909922588809689,0.11030317972784781,3.661517338984293,0.04856032582182117,0.3917410017874763,1.2657472734377568,1.824865383027324,0.2724430641772754,0.9611422765478006,1.6261440706577892,0.4897054676751104,-0.0765234222627171,-0.18244015934691968,-0.03458833609287247,0.06919953703395551,0.25237072765834473,-0.44321720897869366,-0.5998800653389513,0.15117635458958095,0.17152746597699287,2.0981172248521958,1.9062125107768622,0.8691865207095048,-0.5099333245444402
3,643
Nuclear inner membrane
9
24
2.691747
0.007108
Q9UH99,O75844,Q8N6S5,P50402,Q9H1E5,Q9BTV4,Q8IXM6,Q14739,Q5SNT2
Localization
GO Cellular component
msigdb_gocc
164,217,104,396,181,311,89,281,377
217,3390,769,1586,1521,1002,396,3414,485,959,1409,814,281,1810,377,89,104,1461,2067,656,311,181,164,926
1.659614804060893,-1.019604048841438,0.4702158680735321,-0.0765234222627171,-0.03458833609287247,0.2724430641772754,1.105997161876891,-1.0436847151728275,0.8691865207095048,0.31242405485919195,0.027862332156932304,0.4310823742970927,1.4566081122737937,-0.18244015934691968,1.1417856605713883,2.4988272513624805,2.3928800946790516,0.007105158915106008,-0.28994201948861137,0.6247218507870246,1.3356969350852728,1.9062125107768622,1.9867347928109564,0.3521891223123161
3,643
Decreased activity of mitochondrial complex i
20
37
2.688401
0.00718
Q9UBX3,O75380,Q96CU9,O75648,P03886,O75306,O96000,O43676,Q9Y584,Q9Y6M9,O75489,Q5JPH6,Q8N183,Q96EY7,Q70HW3,O75251,O00217,P56556,Q86Y39,Q9H0R6
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
144,650,413,536,277,535,664,50,308,183,696,834,602,747,357,366,734,624,497,510
734,50,366,535,650,696,536,664,277,3080,2605,1939,3129,1328,2045,624,834,2509,357,497,865,602,1309,1861,413,747,1240,2235,510,993,1017,2405,1508,144,1437,308,183
0.5091440599781275,3.107332731050088,1.1596174162013977,0.776099228012361,0.6247218507870246,0.5671569209643074,0.776099228012361,0.6055828069993638,1.4566081122737937,-0.7369966820229626,-0.5099333245444402,-0.24674747021415624,-0.7601130162085916,0.06919953703395551,-0.28994201948861137,0.6628536231131278,0.4114378359281686,-0.465386116003162,1.1951570795527422,0.850660633843561,0.3917410017874763,0.7007922534137548,0.08978035873173802,-0.2038119362780547,1.0519984666463416,0.5091440599781275,0.13076838476814698,-0.3552276637336356,0.832089227524965,0.29246072303462184,0.2724430641772754,-0.42111741427401633,-0.013711595274741894,2.1296580535061174,0.027862332156932304,1.3704358233118867,1.9062125107768622
3,643
Cholesterol binding
9
16
2.686136
0.007228
O75477,P45880,P30536,O95772,P61916,O94905,Q9H4L5,Q14108,P21796
Functions
GO Molecular function
msigdb_gomf
322,261,106,394,466,334,345,444,278
2416,322,334,394,3079,278,2316,106,783,261,466,444,555,1607,1470,345
-0.44321720897869366,1.3008013122061457,1.2657472734377568,1.105997161876891,-0.7369966820229626,1.4566081122737937,-0.39908622494449625,2.377631431346862,0.4506749437853009,1.5418361654019872,0.9244936801618757,0.9794004819604001,0.7573430676997512,-0.0765234222627171,0.007105158915106008,1.2481603149029503
3,643
Lumenal side of endoplasmic reticulum membrane
7
10
2.682322
0.007311
P30511,O15533,P51572,Q8TCT9,P10321,P27824,P27797
Localization
GO Cellular component
msigdb_gocc
6,329,397,364,48,118,539
329,1139,579,48,539,118,6,397,1762,364
1.2832942009953483,0.17152746597699287,0.71968985939333,3.135226461008061,0.776099228012361,2.285531889164803,4.673387267370069,1.105997161876891,-0.16113177748554827,1.1774078138827289
3,643
Mitochondrial myopathy
19
35
2.678206
0.007402
O75380,Q96CU9,P03886,O75306,O96000,Q9BUK6,O43676,Q9Y6M9,O75489,P12235,Q8IUX1,Q7LG56,P00403,Q96RR1,Q8N183,O75251,O00217,P56556,Q86Y39
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
650,413,277,535,664,45,50,183,696,581,865,864,87,603,602,366,734,624,497
734,50,847,366,535,650,696,664,1885,87,1000,277,953,581,3080,2605,3129,1221,624,1896,864,497,865,602,1309,413,603,2235,45,1017,2405,1508,1923,1925,183
0.5091440599781275,3.107332731050088,0.3917410017874763,1.1596174162013977,0.776099228012361,0.6247218507870246,0.5671569209643074,0.6055828069993638,-0.2252475557449799,2.5138506890054337,0.2724430641772754,1.4566081122737937,0.31242405485919195,0.71968985939333,-0.7369966820229626,-0.5099333245444402,-0.7601130162085916,0.13076838476814698,0.6628536231131278,-0.2252475557449799,0.3917410017874763,0.850660633843561,0.3917410017874763,0.7007922534137548,0.08978035873173802,1.0519984666463416,0.7007922534137548,-0.3552276637336356,3.204557850940264,0.2724430641772754,-0.42111741427401633,-0.013711595274741894,-0.2252475557449799,-0.2252475557449799,1.9062125107768622
3,643
Glycolipid binding
7
11
2.674917
0.007475
P07602,Q9UM22,P50897,O14773,Q92643,Q9NWW5,O43292
Functions
GO Molecular function
msigdb_gomf
231,51,244,25,187,252,373
25,373,231,244,958,1525,187,252,3210,492,51
3.661517338984293,1.1417856605713883,1.6261440706577892,1.592529825004484,0.31242405485919195,-0.03458833609287247,1.8575044941143102,1.592529825004484,-0.8065769270037231,0.8691865207095048,3.037189084386894
3,643
Sterol binding
9
19
2.674446
0.007485
O75477,P45880,P30536,O95772,P61916,O94905,Q9H4L5,Q14108,P21796
Functions
GO Molecular function
msigdb_gomf
322,261,106,394,466,334,345,444,278
2416,322,334,394,3079,278,2488,2316,106,783,261,466,444,555,1963,1774,1607,1470,345
-0.44321720897869366,1.3008013122061457,1.2657472734377568,1.105997161876891,-0.7369966820229626,1.4566081122737937,-0.465386116003162,-0.39908622494449625,2.377631431346862,0.4506749437853009,1.5418361654019872,0.9244936801618757,0.9794004819604001,0.7573430676997512,-0.24674747021415624,-0.16113177748554827,-0.0765234222627171,0.007105158915106008,1.2481603149029503
3,643
Glycolipid biosynthetic process
9
12
2.673921
0.007497
O60512,Q8NBX0,Q969N2,Q96S52,Q5H8A4,Q16739,Q16880,Q92643,O43292
Processes and pathways
GO Biological process
msigdb_gobp
253,33,586,234,207,282,246,187,373
373,253,2801,282,246,207,33,187,586,234,1165,649
1.1417856605713883,1.5756684289722063,-0.5998800653389513,1.4566081122737937,1.592529825004484,1.742673161727919,3.476322734521235,1.8575044941143102,0.71968985939333,1.6261440706577892,0.17152746597699287,0.6438120248840904
3,643
Endoplasmic reticulum
88
220
2.672608
0.007526
Q6UW68,P27544,Q86Y07,O96005,Q8WUJ1,O95674,P43307,O43852,Q86XL3,Q14257,Q96AG4,Q4ZIN3,P27797,P51648,Q8NF37,Q9Y680,P07237,P13674,O15260,Q96G23,Q9P2W9,Q8IV08,Q70UQ0,Q5T9L3,Q13162,P37268,Q86UE4,Q13438,P84157,Q92791,P27824,Q9BUN8,P30533,Q96PC5,Q9BT22,Q9UKV5,Q13217,O43169,P14625,Q96A33,Q9BRK0,Q96KA5,O15460,Q15293,Q96GC9,O95470,Q96S66,Q9UGP8,Q96KC8,O95197,P49257,O00264,Q9NWW5,Q9UM00,Q14696,Q9H3N1,Q9H6H4,P14314,O75477,Q8TCJ2,Q9P035,O94905,Q9H3G5,P30101,Q13724,Q8TCT9,Q9NQC3,P61619,Q12981,O43292,P04843,P51572,P04844,P50402,P51571,Q8NBS9,Q9HCU5,Q96A57,Q15084,O60831,P13667,Q14697,Q99442,O14967,Q12797,Q6PIU2,Q15800,Q8N0U8
Localization
Protein Atlas Subcellular
protein_atlas_subcellular_location_all
1,5,520,9,10,513,14,16,18,20,542,27,539,32,557,39,41,47,52,55,58,65,70,69,72,73,85,91,94,113,118,122,132,154,161,169,166,174,184,188,189,192,194,203,208,209,219,221,228,223,238,236,252,259,263,297,312,324,322,336,340,334,344,352,356,364,365,363,367,373,384,397,395,396,400,402,415,422,419,434,443,445,467,469,481,488,487,498
236,875,824,469,755,52,611,194,174,2950,373,2357,16,621,434,848,322,805,1883,3390,1214,334,223,2035,209,513,9,1621,384,395,2420,3594,1445,41,2991,2992,638,2852,580,443,47,324,184,1447,1402,2666,2485,1623,3563,782,2667,2099,2546,5,758,539,118,2955,352,132,3488,1937,783,772,908,73,1030,2860,14,1590,2548,1940,2103,1670,1632,3564,2821,238,396,909,3047,400,397,32,1525,2772,1997,2047,2328,1063,363,3544,2110,3005,2822,2962,1115,2373,2775,3396,2165,2374,1455,2919,1456,2329,2823,1297,2920,1408,1745,2921,641,2050,1846,94,681,829,3049,2923,481,367,2617,72,166,2114,91,356,20,2567,263,445,555,915,1893,419,203,2870,1152,487,1095,3170,27,3234,1120,69,2060,2930,488,1529,1,70,85,1418,18,520,65,3235,498,1645,402,557,837,2634,336,364,1338,10,1764,113,728,188,422,542,1818,1903,654,55,208,890,192,228,154,219,467,618,1468,1605,189,2018,161,122,633,1775,1610,344,297,312,415,365,995,2023,252,1828,1315,798,340,1785,3613,1718,58,1280,660,1080,221,169,259,2411,39,873
1.6093549777202447,0.37199154172998977,0.4114378359281686,0.9061027846832771,0.4897054676751104,3.0230894408053492,0.6818469365208409,1.824865383027324,1.9385192969684373,-0.6681029929832263,1.1417856605713883,-0.42111741427401633,4.095354306912875,0.6628536231131278,0.99761495810321,0.3917410017874763,1.3008013122061457,0.4310823742970927,-0.2252475557449799,-1.019604048841438,0.13076838476814698,1.2657472734377568,1.64289728589414,-0.28994201948861137,1.7095549611048153,0.8134720365945656,4.243451171065863,-0.09758260109774661,1.1239123190922105,1.105997161876891,-0.44321720897869366,-1.6752169966089951,0.007105158915106008,3.2870083892475765,-0.6909922588809689,-0.6909922588809689,0.6438120248840904,-0.6225474635721432,0.71968985939333,0.9794004819604001,3.163027731650402,1.3008013122061457,1.8900097097013104,0.007105158915106008,0.027862332156932304,-0.5323126699925248,-0.465386116003162,-0.09758260109774661,-1.390041774081608,0.4506749437853009,-0.5323126699925248,-0.3116375849262432,-0.48762464822389984,4.73149126850177,0.4897054676751104,0.776099228012361,2.285531889164803,-0.6681029929832263,1.2128654372087189,2.192370287416088,-1.1653727114302805,-0.24674747021415624,0.4506749437853009,0.4702158680735321,0.3521891223123161,2.647833677324652,0.25237072765834473,-0.6225474635721432,4.1449986542955966,-0.0765234222627171,-0.48762464822389984,-0.24674747021415624,-0.3116375849262432,-0.11870343366061006,-0.09758260109774661,-1.390041774081608,-0.5998800653389513,1.6093549777202447,1.105997161876891,0.3521891223123161,-0.7139566269396745,1.0880399570282553,1.105997161876891,3.476322734521235,-0.03458833609287247,-0.5772854996002308,-0.2683121372291175,-0.28994201948861137,-0.39908622494449625,0.23224335926748166,1.1774078138827289,-1.2892692909305767,-0.3116375849262432,-0.6909922588809689,-0.5998800653389513,-0.6681029929832263,0.1918220918189678,-0.42111741427401633,-0.5772854996002308,-1.019604048841438,-0.333399306791712,-0.42111741427401633,0.007105158915106008,-0.6452882514774274,0.007105158915106008,-0.39908622494449625,-0.5998800653389513,0.08978035873173802,-0.6452882514774274,0.027862332156932304,-0.16113177748554827,-0.6452882514774274,0.6438120248840904,-0.28994201948861137,-0.2038119362780547,2.4535901140386045,0.5863945968863824,0.4114378359281686,-0.7139566269396745,-0.6452882514774274,0.8876671508686171,1.1596174162013977,-0.5099333245444402,2.692012537294508,1.9706953778300438,-0.3116375849262432,2.483776090582276,1.1951570795527422,3.8042718536546554,-0.48762464822389984,1.5418361654019872,0.9794004819604001,0.7573430676997512,0.3521891223123161,-0.2252475557449799,1.0339137070490352,1.792091065872174,-0.6225474635721432,0.17152746597699287,0.8691865207095048,0.21206060116262693,-0.7833062289105431,3.569421755662869,-0.829925724951396,0.1918220918189678,2.7651210132024806,-0.28994201948861137,-0.6452882514774274,0.8691865207095048,-0.03458833609287247,5.873073786689076,2.7651210132024806,2.5288465238651407,0.027862332156932304,3.906629108755367,0.8134720365945656,2.808677111591547,-0.829925724951396,0.850660633843561,-0.09758260109774661,1.0880399570282553,0.7573430676997512,0.4114378359281686,-0.5099333245444402,1.2657472734377568,1.1774078138827289,0.06919953703395551,4.231204838358074,-0.16113177748554827,2.3470478270665613,0.5285319592869173,1.8575044941143102,1.0339137070490352,0.776099228012361,-0.18244015934691968,-0.2252475557449799,0.6247218507870246,2.980646976640566,1.7261314689431049,0.37199154172998977,1.8412017569470738,1.64289728589414,2.06645172244257,1.659614804060893,0.9244936801618757,0.6818469365208409,0.007105158915106008,-0.0765234222627171,1.8575044941143102,-0.2683121372291175,2.018717139797755,2.254597454452404,0.6628536231131278,-0.16113177748554827,-0.0765234222627171,1.2481603149029503,1.4050196301598754,1.3356969350852728,1.0519984666463416,1.1774078138827289,0.29246072303462184,-0.2683121372291175,1.592529825004484,-0.18244015934691968,0.08978035873173802,0.4506749437853009,1.2657472734377568,-0.16113177748554827,-1.890577869245987,-0.13988634815318823,2.9094252815894692,0.11030317972784781,0.6247218507870246,0.23224335926748166,1.659614804060893,1.9706953778300438,1.5587706046077934,-0.42111741427401633,3.314313786509081,0.3917410017874763
3,643