term stringlengths 2 121 | overlap int64 6 281 | setsize int64 7 499 | score float64 1.96 10.6 | pval float64 0 0.05 | edge stringlengths 41 1.97k | type stringclasses 5 values | subtype stringclasses 24 values | subtype_key stringclasses 24 values | edge_idxs stringlengths 11 1.17k | ann_idxs stringlengths 19 2.31k | ann_vals stringlengths 124 9.94k | sig_size int64 2.2k 3.73k |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Slc mediated transmembrane transport | 11 | 22 | 2.680549 | 0.00735 | P12236,P30825,Q9UBX3,O00400,Q8TB61,Q70HW3,Q9H2J7,P12235,P11166,Q9Y6M7,P53985 | Processes and pathways | Reactome Pathways | msigdb_reactome | 480,71,103,41,137,11,457,235,497,315,473 | 41,664,719,497,235,480,1296,71,578,895,473,922,1922,1507,11,3153,137,1736,457,1027,103,315 | 2.926074846462015,0.5634104540353521,0.49421881017368724,0.8065529251182306,1.4987330608256157,0.8462116178421202,0.017588330277042968,2.553171637047871,0.6861169405393601,0.325039233943853,0.8593782894230385,0.2963992009112666,-0.30599468976821914,-0.08837640269605082,3.6755062380906676,-1.7152768494821569,2.1059164207950953,-0.21177118338905118,0.8987214683111048,0.1951211504020895,2.300945191798539,1.2303064299473192 | 3,220 |
Mitochondrial protein import | 15 | 36 | 2.679947 | 0.007363 | Q10713,O14925,P12236,Q9Y5J6,Q9NS69,P12235,Q13505,O96008,Q9Y584,Q99595,Q9Y5J9,P62072,O60830,P21796,Q8N4H5 | Processes and pathways | Reactome Pathways | msigdb_reactome | 195,97,480,413,45,235,143,423,49,84,344,153,26,28,62 | 97,821,26,2880,555,1457,1154,740,423,1269,1522,3022,235,480,28,2437,2537,1498,153,195,143,746,1009,790,62,84,2846,2294,45,1050,845,1761,502,49,413,344 | 2.354208142416853,0.39607780869964226,3.1202885925230546,-0.8876655391405662,0.7130729829609895,-0.07312611883137438,0.09217774053922007,0.46633196825224094,0.9637783554965194,0.03257833492512616,-0.10366479969187105,-1.1195734835314772,1.4987330608256157,0.8462116178421202,3.0914668286417912,-0.5647669902106163,-0.6145736537180316,-0.08837640269605082,1.9840933186443066,1.7224537296137836,2.0839194517291406,0.46633196825224094,0.20968982025645352,0.4242723854370574,2.665974910710302,2.4595918230799607,-0.8354661427807923,-0.48268182979148255,2.8965139805223146,0.18051850104213735,0.3819335469967939,-0.22737331928668936,0.8065529251182306,2.8370461170260968,1.0025089619631318,1.155226944031845 | 3,220 |
Nucleotide transport | 11 | 13 | 2.672561 | 0.007527 | Q08722,P12236,O00400,Q8TB61,Q9H2D1,P12235,Q6NUK1,Q9HC21,P33897,Q9BSK2,P05141 | Processes and pathways | GO Biological process | msigdb_gobp | 547,480,41,137,107,235,625,533,633,348,664 | 41,696,664,235,480,633,2244,547,625,137,348,107,533 | 2.926074846462015,0.5219848971605708,0.5634104540353521,1.4987330608256157,0.8462116178421202,0.6045715368978304,-0.4664008031269134,0.7265093315527947,0.6182338533453158,2.1059164207950953,1.1426321922261868,2.2688006578891002,0.7532993971393909 | 3,220 |
Sphingolipid metabolism | 8 | 10 | 2.668928 | 0.007609 | P07602,P04062,Q16739,O15269,Q9NZ01,O95470,P17900,Q13510 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 67,140,561,422,307,148,527,59 | 422,1267,148,140,67,527,616,59,561,307 | 0.9637783554965194,0.03257833492512616,2.028631668550595,2.0949263106223306,2.625151948477759,0.7532993971393909,0.6318674029638589,2.6863034556568013,0.7130729829609895,1.2551491998763629 | 3,220 |
Alcohol binding | 8 | 17 | 2.664846 | 0.007702 | O95772,Q14108,O15118,P35610,P30536,P09455,P45880,P21796 | Functions | GO Molecular function | msigdb_gomf | 128,101,135,396,394,180,58,28 | 437,135,1349,3110,1323,128,2897,180,28,2081,394,396,58,1190,101,2383,1045 | 0.937832102041449,2.1168898459726213,-0.012501405263775458,-1.3805716198597155,0.0025618247362464894,2.149710642995687,-0.9051717595444062,1.7916438703696143,3.0914668286417912,-0.38565873026838904,1.0153693117770466,1.0153693117770466,2.6863034556568013,0.07733154678623776,2.3116287576952588,-0.5317956557309711,0.18051850104213735 | 3,220 |
Macromolecule transmembrane transporter activity | 11 | 13 | 2.65278 | 0.007983 | O14925,P51991,Q15388,Q9NS69,O96008,Q9Y584,P49755,O94826,Q99595,Q9UGP8,O60830 | Functions | GO Molecular function | msigdb_gomf | 97,520,746,45,423,49,595,740,84,671,26 | 97,26,740,423,595,520,1303,805,746,84,45,671,49 | 2.354208142416853,3.1202885925230546,0.46633196825224094,0.9637783554965194,0.6590488057153554,0.7666533960815253,0.017588330277042968,0.4101906969059821,0.46633196825224094,2.4595918230799607,2.8965139805223146,0.5634104540353521,2.8370461170260968 | 3,220 |
Nuclear outer membrane endoplasmic reticulum membrane network | 162 | 344 | 2.64663 | 0.00813 | Q15125,Q9H8Y8,Q969V3,Q6RW13,Q8N0U8,P30519,P27544,Q92575,P57088,P43307,O95197,Q15629,Q96AG4,P24390,Q15392,Q8N4V1,Q9Y282,O75844,O00400,Q8N511,O14975,O00560,Q9UKU0,Q9Y320,O43731,Q9BQE5,Q12797,Q14739,Q15800,Q99720,P09601,P35613,P51572,O95864,P61009,Q86YN1,P49755,Q13438,Q9P2W9,Q9HD20,Q9HCU5,O60725,Q14108,Q9BUN8,Q06136,Q5BJF2,P61026,Q7Z2K6,P67812,P33897,Q969X5,Q5BJH7,Q9BVC6,Q8IV08,O95772,P55061,Q86XL3,Q16850,Q4ZIN3,Q8TB61,Q15363,P49458,Q9NUQ2,O95470,Q9UGP8,Q9NZ08,Q96G23,O75340,O00767,Q5JRA6,Q53GQ0,O43909,Q8N5M9,Q9BRR6,Q9NTJ5,Q9H6H4,Q9NP80,Q6Y1H2,Q6NUK4,P51648,Q9BV10,Q9Y6B6,Q96N66,Q9UBV2,Q9NVV0,Q15904,Q96RQ1,Q5VV42,Q96PC5,O43292,Q9BUR5,Q9Y5Y5,P38435,Q9H3N1,A1L0T0,Q9H2C2,Q8NHH9,Q86UE4,Q9BU23,O00264,Q86SQ9,P48449,O60858,Q03518,Q8NF37,Q9NPA0,O95674,Q96A33,O15260,Q10472,Q9Y679,P62942,Q5T9L3,Q9NQC3,Q9NZ01,O76024,Q9Y3B3,Q9BVG9,Q96JJ7,Q8NBI6,P16615,P16435,Q15005,O43852,Q99523,Q96KC8,Q9Y5M8,Q9H490,Q07065,Q9BRK0,Q9P035,P35610,O14653,Q6NUM9,Q6P1A2,O43264,Q9BT22,Q9Y4P3,Q9NX47,Q9Y5Z9,O15269,O14735,Q9C0D9,Q9Y2B2,O75298,Q14534,Q9UBU6,Q70UQ0,Q16799,O75845,P27824,P51571,Q9UBM7,Q6NUQ4,P50402,Q99442,P46977,Q96HY6,O95070,Q15041,O75915,P10321 | Localization | GO Cellular component | msigdb_gocc | 3,516,6,524,13,14,519,531,528,21,23,24,539,27,29,33,36,40,41,42,542,541,46,563,52,53,559,57,61,63,576,578,584,583,585,79,595,597,85,90,611,100,101,104,616,108,623,114,115,633,634,125,640,126,128,637,132,133,655,137,141,648,146,148,671,152,154,662,661,678,164,673,169,170,693,692,174,687,686,176,182,704,192,715,714,711,201,209,218,219,222,227,230,233,234,238,237,236,247,255,257,261,259,264,266,267,271,272,268,277,278,286,297,306,307,316,327,326,325,333,342,347,354,360,369,379,380,385,383,399,402,396,393,409,410,406,417,418,420,421,422,437,445,454,448,462,465,463,467,470,471,472,476,483,481,493,488,498,503,505,509,510 | 769,234,1972,904,255,41,1801,541,661,1014,393,830,437,757,985,542,2833,1485,969,268,422,1267,406,219,1974,820,52,360,1348,673,1152,959,100,1349,259,448,662,1084,3110,718,40,470,1031,509,316,1015,832,1323,1490,503,23,1576,148,1744,3109,1628,271,128,583,784,1157,728,945,2273,860,3045,1714,1461,2308,576,510,3012,1377,347,342,880,1462,1213,2715,27,802,519,3070,471,3083,2759,14,1296,2056,1088,633,1216,396,578,1275,230,2017,1404,2718,21,488,2472,261,742,1034,648,595,1609,481,1496,472,584,176,826,909,2588,2866,2247,637,2443,1657,528,2020,1407,1880,585,864,623,1720,2639,1749,1303,2250,2777,1304,1060,286,1947,2283,115,1817,264,1440,1724,616,383,1019,2124,277,559,731,2381,1532,597,949,1356,101,2662,1986,462,57,354,2856,505,976,2592,3,141,2161,29,1952,24,2544,61,711,467,133,2663,2288,655,164,108,125,992,678,297,1471,209,2800,810,686,409,914,483,886,410,1507,1310,524,2202,936,687,463,2826,114,2916,257,236,1789,132,1022,79,126,1284,3075,13,1619,2164,33,42,1097,169,1641,870,333,266,765,237,979,2727,137,1363,2452,793,1099,3032,816,2420,531,722,713,2482,2888,6,634,272,1259,539,1510,3033,154,1998,498,325,379,192,218,1419,201,1930,872,493,369,1448,63,900,1102,53,399,170,1123,1540,417,247,104,222,182,640,326,752,1045,445,1450,2456,1176,238,2002,1318,233,385,2961,692,516,953,611,90,2004,174,267,306,3019,693,146,714,420,1262,1071,307,152,1289,402,1051,1082,2396,3201,85,2172,476,465,715,671,1676,46,1072,1029,2602,36,454,563,3080,1013,781,327,2174,418,2175,380,227,421,2653,2430,278,704,956 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| 3,220 |
Endoplasmic reticulum golgi intermediate compartment membrane | 18 | 30 | 2.643529 | 0.008205 | Q9Y3B3,Q9Y282,Q15904,Q03518,Q96RQ1,Q8N511,P51572,Q9BVK6,Q15363,Q5BJH7,P49755,O15260,O14653,Q10472,Q969X5,O95070,P24390,Q12907 | Localization | GO Cellular component | msigdb_gocc | 327,36,711,264,201,42,584,752,141,125,595,268,393,277,634,503,27,731 | 393,268,2461,1084,503,27,3070,595,584,1090,1657,864,264,1440,896,277,731,1532,141,711,2288,125,42,634,201,752,1176,36,781,327 | 1.0153693117770466,1.3780223384827002,-0.5813222600056109,0.13650467332375438,0.7932800225164705,3.101086023493359,-1.2113809723326867,0.6590488057153554,0.6725969576878126,0.13650467332375438,-0.180686953630024,0.3535502000193913,1.3901891347163047,-0.05791371087003406,0.325039233943853,1.3658339237407737,0.48029056583855095,-0.10366479969187105,2.0949263106223306,0.5081168661324692,-0.48268182979148255,2.1715089003830492,2.916233933501683,0.6045715368978304,1.6876019624630145,0.46633196825224094,0.09217774053922007,3.014078455797105,0.4383230465774212,1.2053723631183846 | 3,220 |
Golgi cisterna | 17 | 28 | 2.639752 | 0.008297 | Q10713,Q12893,P98194,Q96JB2,Q8NBN3,P51572,Q15363,Q9Y3A3,O95249,Q99523,Q10472,Q9BXS4,Q9Y6B6,Q9H4A6,O00461,Q8TBA6,P0CG08 | Localization | GO Cellular component | msigdb_gocc | 195,677,382,229,39,584,141,703,175,369,277,149,704,314,88,221,729 | 88,175,728,729,1606,584,382,1063,896,2124,277,195,677,2414,141,1167,39,221,3032,816,229,2227,369,149,1286,314,703,704 | 2.4386350380760957,1.803109914230054,0.48029056583855095,0.48029056583855095,-0.14976107776049186,0.6725969576878126,1.0410159526015372,0.16588167285776514,0.325039233943853,-0.4017197370823883,1.3658339237407737,1.7224537296137836,0.5496315311633986,-0.5482582308154097,2.0949263106223306,0.09217774053922007,2.965312360286222,1.5583068029385927,-1.1195734835314772,0.4101906969059821,1.534538665815881,-0.4501643839012559,1.092016293622401,2.0175229570018764,0.03257833492512616,1.2303064299473192,0.5219848971605708,0.5219848971605708 | 3,220 |
Phospholipid metabolism | 18 | 54 | 2.62739 | 0.008604 | Q96N66,Q9NQZ5,Q9BVG9,Q8WUK0,Q10713,P35790,Q9HBU6,Q8NF37,O95674,Q8NCC3,Q9NP80,Q9NUQ2,Q9NPH0,Q6P1A2,O14735,Q8IV08,Q9UG56,Q8N2A8 | Processes and pathways | Reactome Pathways | msigdb_reactome | 192,64,326,291,195,248,8,266,271,44,174,146,150,410,437,126,389,127 | 2561,437,969,567,2113,822,271,784,1875,1809,1135,248,1111,594,962,742,1034,2839,1720,804,2741,195,1883,1038,410,2826,126,3075,127,870,937,44,266,813,291,722,1259,192,1394,1960,1011,1102,901,326,1045,445,1081,8,174,150,64,693,146,389 | -0.6312704485557797,0.937832102041449,0.23872600947530984,0.6996089005935843,-0.4017197370823883,0.39607780869964226,1.3780223384827002,0.4242723854370574,-0.2901881007744104,-0.2586989329734473,0.10698851923772369,1.4627412434131177,0.12176409384605623,0.6590488057153554,0.25319391829959953,0.46633196825224094,0.18051850104213735,-0.8354661427807923,-0.21177118338905118,0.4101906969059821,-0.7495074930568375,1.7224537296137836,-0.2901881007744104,0.18051850104213735,1.0025089619631318,-0.8181714233751796,2.160617957746634,-1.2113809723326867,2.160617957746634,0.3535502000193913,0.2820303246081004,2.8965139805223146,1.3901891347163047,0.4101906969059821,1.3168621387496977,0.49421881017368724,0.04753206007602352,1.7340326951249647,-0.027601585489929144,-0.32184297973986525,0.20968982025645352,0.13650467332375438,0.325039233943853,1.2053723631183846,0.18051850104213735,0.9248208500595174,0.15121046465169286,3.834786997734797,1.8145574051151347,2.0175229570018764,2.665974910710302,0.5358230652915174,2.050797739596964,1.0410159526015372 | 3,220 |
Abnormal tissue metabolite concentration | 9 | 19 | 2.618074 | 0.008843 | P56589,Q9Y5Y5,P07602,Q9NZJ7,P17900,P33897,O75381,P06865,P06280 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 512,227,67,359,527,633,372,285,284 | 1347,372,284,285,67,1681,527,633,1075,649,1219,512,1080,2779,1894,1259,359,1761,227 | -0.012501405263775458,1.0665646357789607,1.329137999738356,1.329137999738356,2.625151948477759,-0.1962091472678085,0.7532993971393909,0.6045715368978304,0.15121046465169286,0.5771599918037926,0.06244972498315363,0.7799802251689579,0.15121046465169286,-0.7837372383934156,-0.2901881007744104,0.04753206007602352,1.1173718443197118,-0.22737331928668936,1.5464329024539194 | 3,220 |
Sterol metabolic process | 18 | 42 | 2.616911 | 0.008873 | Q15125,P48449,Q16850,O15118,Q14534,Q9H2C2,P04062,P35610,P49748,Q15800,Q9BQE5,Q8WTV0,O75845,Q6P1A2,Q14739,P16435,Q15392,P54646 | Processes and pathways | GO Biological process | msigdb_gobp | 3,261,133,135,462,238,140,396,433,61,53,54,470,410,57,347,29,373 | 135,3110,470,1031,1323,1157,140,636,1212,894,347,2504,2468,396,1275,760,2538,261,433,2123,373,1190,2192,3048,2253,2947,462,57,2477,3,2543,29,2544,61,133,410,54,53,238,476,2555,1676 | 2.1168898459726213,-1.3805716198597155,0.8593782894230385,0.18051850104213735,0.0025618247362464894,0.09217774053922007,2.0949263106223306,0.5908803010183907,0.06244972498315363,0.325039233943853,1.1426321922261868,-0.5979243699912032,-0.5813222600056109,1.0153693117770466,0.03257833492512616,0.4523428510935623,-0.6145736537180316,1.4144582543439532,0.9508178956967717,-0.4017197370823883,1.0665646357789607,0.07733154678623776,-0.43397226707902753,-1.156115218044601,-0.4664008031269134,-0.9757397882754897,0.8856330846497343,2.696447157783284,-0.5813222600056109,4.059475865189276,-0.6145736537180316,3.081835643844188,-0.6145736537180316,2.6761460554500984,2.1278466494928105,1.0025089619631318,2.7368859058038453,2.7469618056075022,1.4987330608256157,0.8593782894230385,-0.6145736537180316,-0.180686953630024 | 3,220 |
Glycosidase | 7 | 16 | 2.600835 | 0.0093 | Q9BTY2,P04062,P04066,P54802,O60502,P06865,P06280 | Functions | Protein Atlas Molecular function | protein_atlas_molecular_function | 292,140,300,240,270,285,284 | 1654,270,140,300,284,285,1681,362,614,2438,240,2510,1356,2023,1167,292 | -0.180686953630024,1.3780223384827002,2.0949263106223306,1.2799015060822838,1.329137999738356,1.329137999738356,-0.1962091472678085,1.104706025521293,0.6318674029638589,-0.5647669902106163,1.4867565983726359,-0.5979243699912032,-0.012501405263775458,-0.3536657728297462,0.09217774053922007,1.3168621387496977 | 3,220 |
Nucleotide transmembrane transporter activity | 10 | 12 | 2.59483 | 0.009464 | P12236,O00400,Q8TB61,Q9H2D1,P12235,Q6NUK1,Q9HC21,P33897,Q9BSK2,P05141 | Functions | GO Molecular function | msigdb_gomf | 480,41,137,107,235,625,533,633,348,664 | 41,696,664,235,480,633,2244,625,137,348,107,533 | 2.926074846462015,0.5219848971605708,0.5634104540353521,1.4987330608256157,0.8462116178421202,0.6045715368978304,-0.4664008031269134,0.6182338533453158,2.1059164207950953,1.1426321922261868,2.2688006578891002,0.7532993971393909 | 3,220 |
Organophosphate ester transmembrane transporter activity | 10 | 12 | 2.59483 | 0.009464 | P12236,O00400,Q8TB61,Q9H2D1,P12235,Q6NUK1,Q9HC21,P33897,Q9BSK2,P05141 | Functions | GO Molecular function | msigdb_gomf | 480,41,137,107,235,625,533,633,348,664 | 41,696,664,235,480,633,2244,625,137,348,107,533 | 2.926074846462015,0.5219848971605708,0.5634104540353521,1.4987330608256157,0.8462116178421202,0.6045715368978304,-0.4664008031269134,0.6182338533453158,2.1059164207950953,1.1426321922261868,2.2688006578891002,0.7532993971393909 | 3,220 |
Cation transmembrane transport | 49 | 124 | 2.586243 | 0.009703 | P05067,P98194,P21281,Q96AQ8,Q4KMQ2,Q70HW3,Q9Y619,Q9HC21,Q8IYU8,P00846,P62942,P21796,P05141,P27105,Q8N4V1,Q9H4I9,Q13423,Q00325,O00400,Q9NW15,P05023,O75964,Q9Y6M7,Q9UHD1,P20020,Q9NVV0,Q96ER9,Q9HC07,P30825,P24539,Q9H2J7,Q7KZN9,Q9UDW1,O75027,O43772,P08195,P13073,O14548,P16615,Q9HD20,Q9UJZ1,P56385,O75251,Q96NB2,P12235,Q96ES6,P78417,O75947,P51790 | Processes and pathways | GO Biological process | msigdb_gobp | 636,382,381,392,654,11,142,533,530,25,286,28,664,407,33,165,161,676,41,694,424,47,315,573,697,714,581,197,71,455,457,332,204,81,458,719,212,592,342,90,477,482,600,486,235,242,246,630,511 | 41,1710,592,2705,1292,458,2177,81,600,799,1457,630,47,727,3082,849,25,424,987,636,664,2341,1269,2956,2753,1602,2897,719,1522,2793,2146,1212,235,212,342,3125,697,824,381,3145,2854,28,455,2437,407,2115,2147,2505,1296,71,1057,2016,3047,882,1463,1552,2408,1464,2996,1553,511,1113,922,1246,482,1114,1303,1528,286,246,382,676,1983,1141,1019,3089,1064,161,2354,2414,1922,654,1472,11,332,1284,530,33,1120,3153,841,2453,392,581,242,1998,486,3000,1043,1315,1205,2456,2487,457,1514,165,1027,1179,197,533,90,1207,714,694,2396,204,573,2266,477,1072,1868,1428,142,315 | 2.926074846462015,-0.21177118338905118,0.6590488057153554,-0.7324683402938643,0.017588330277042968,0.8856330846497343,-0.43397226707902753,2.4804894818760905,0.6454723370713444,0.4101906969059821,-0.07312611883137438,0.6045715368978304,2.8370461170260968,0.48029056583855095,-1.2299257497204847,0.36775773642059567,3.1776123860617123,0.9637783554965194,0.22422470806964243,0.5908803010183907,0.5634104540353521,-0.5153789425131554,0.03257833492512616,-0.9935197104671422,-0.7665970008859604,-0.14976107776049186,-0.9051717595444062,0.49421881017368724,-0.10366479969187105,-0.8009285846731938,-0.417824150950574,0.06244972498315363,1.4987330608256157,1.6291279725959298,1.155226944031845,-1.4574777798783827,0.5219848971605708,0.39607780869964226,1.0410159526015372,-1.6346231136290568,-0.8528131358802458,3.0914668286417912,0.8987214683111048,-0.5647669902106163,1.0025089619631318,-0.4017197370823883,-0.417824150950574,-0.5979243699912032,0.017588330277042968,2.553171637047871,0.16588167285776514,-0.3536657728297462,-1.156115218044601,0.33931075924719056,-0.07312611883137438,-0.11899154943441288,-0.5482582308154097,-0.07312611883137438,-1.0652042358274294,-0.11899154943441288,0.7799802251689579,0.12176409384605623,0.2963992009112666,0.04753206007602352,0.8462116178421202,0.12176409384605623,0.017588330277042968,-0.10366479969187105,1.329137999738356,1.4747593560996295,1.0410159526015372,0.5496315311633986,-0.3377332475042113,0.10698851923772369,0.1951211504020895,-1.2485328176499129,0.16588167285776514,1.9054783305621512,-0.5153789425131554,-0.5482582308154097,-0.30599468976821914,0.5771599918037926,-0.07312611883137438,3.6755062380906676,1.180346153859077,0.03257833492512616,0.7532993971393909,3.072192431575852,0.12176409384605623,-1.7152768494821569,0.3819335469967939,-0.5647669902106163,1.0282049357246734,0.6861169405393601,1.4867565983726359,-0.3377332475042113,0.833018588532747,-1.0652042358274294,0.18051850104213735,0.017588330277042968,0.07733154678623776,-0.5647669902106163,-0.5813222600056109,0.8987214683111048,-0.08837640269605082,1.8828569071488772,0.1951211504020895,0.09217774053922007,1.7224537296137836,0.7532993971393909,2.4281343418587498,0.07733154678623776,0.5081168661324692,0.5358230652915174,-0.5317956557309711,1.6759461511432516,0.6996089005935843,-0.4664008031269134,0.8593782894230385,0.16588167285776514,-0.27442293885448277,-0.04273894393938979,2.0949263106223306,1.2303064299473192 | 3,220 |
Fever | 18 | 79 | 2.581568 | 0.009835 | P07602,P06280,Q9HC07,P03886,P23786,Q9NZJ7,P28070,Q9BW27,P10253,P35610,Q9NR77,Q8NFH4,P10644,Q9NZ08,P00846,Q9ULK5,Q13510,Q14739 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 67,284,197,7,168,359,202,365,362,396,243,371,341,152,25,122,59,57 | 2047,1239,1626,1292,2907,2607,2373,784,849,419,25,7,2931,1837,284,2533,67,2792,2986,362,341,1839,1212,833,1745,2311,2715,168,2757,3070,202,396,1682,760,825,2120,1354,1609,1035,584,1945,2248,1465,990,2060,774,1018,2253,652,1501,1116,1726,59,709,2382,57,2722,1333,1888,1505,679,1169,609,371,2029,1565,2454,365,197,2747,1515,243,152,359,2649,2106,122,782,2560 | -0.36964083848210133,0.04753206007602352,-0.16520434781562565,0.017588330277042968,-0.9227318742944672,-0.6648079405015793,-0.5317956557309711,0.4242723854370574,0.36775773642059567,0.9767136049402716,3.1776123860617123,3.869760435421595,-0.9580154630503087,-0.27442293885448277,1.329137999738356,-0.6145736537180316,2.625151948477759,-0.8009285846731938,-1.0471974781596876,1.104706025521293,1.155226944031845,-0.27442293885448277,0.06244972498315363,0.3819335469967939,-0.22737331928668936,-0.49900777230689414,-0.7324683402938643,1.8373970276820892,-0.7665970008859604,-1.2113809723326867,1.6759461511432516,1.0153693117770466,-0.1962091472678085,0.4523428510935623,0.39607780869964226,-0.4017197370823883,-0.012501405263775458,-0.14976107776049186,0.18051850104213735,0.6725969576878126,-0.32184297973986525,-0.4664008031269134,-0.07312611883137438,0.22422470806964243,-0.36964083848210133,0.4383230465774212,0.1951211504020895,-0.4664008031269134,0.5771599918037926,-0.08837640269605082,0.12176409384605623,-0.21177118338905118,2.6863034556568013,0.5081168661324692,-0.5317956557309711,2.696447157783284,-0.7324683402938643,0.0025618247362464894,-0.2901881007744104,-0.08837640269605082,0.5496315311633986,0.09217774053922007,0.6454723370713444,1.0793025351530954,-0.3536657728297462,-0.11899154943441288,-0.5647669902106163,1.104706025521293,1.7224537296137836,-0.7495074930568375,-0.08837640269605082,1.4867565983726359,1.9952538492017513,1.1173718443197118,-0.681649331993938,-0.38565873026838904,2.182383532354164,0.4383230465774212,-0.6145736537180316 | 3,220 |
Horizontal nystagmus | 6 | 23 | 2.577285 | 0.009958 | P07602,Q9H061,P04062,O95831,P00846,O14773 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 67,9,140,55,25,214 | 2076,1801,214,798,1323,55,25,140,67,1007,2773,649,3112,1138,1465,1224,2290,1697,9,1028,694,359,1052 | -0.38565873026838904,-0.2586989329734473,1.6173742844059265,0.4101906969059821,0.0025618247362464894,2.7166936523547114,3.1776123860617123,2.0949263106223306,2.625151948477759,0.20968982025645352,-0.7837372383934156,0.5771599918037926,-1.3805716198597155,0.10698851923772369,-0.07312611883137438,0.06244972498315363,-0.48268182979148255,-0.1962091472678085,3.817243530612087,0.1951211504020895,0.5358230652915174,1.1173718443197118,0.18051850104213735 | 3,220 |
Protein transmembrane transport | 19 | 28 | 2.5593 | 0.010488 | P50542,P31751,Q9UGP8,Q15629,O60830,Q07820,Q9NS69,O96008,Q9Y584,O95831,O75298,P49755,Q99595,Q9Y5Y5,O14925,Q99442,Q15388,O94826,O75381 | Processes and pathways | GO Biological process | msigdb_gobp | 649,276,671,24,26,805,45,423,49,55,448,595,84,227,97,493,746,740,372 | 97,821,26,448,372,740,55,423,3022,276,595,649,2020,2060,1303,805,746,24,1009,3007,1894,493,84,2294,45,671,49,227 | 2.354208142416853,0.39607780869964226,3.1202885925230546,0.9117840142979674,1.0665646357789607,0.46633196825224094,2.7166936523547114,0.9637783554965194,-1.1195734835314772,1.3658339237407737,0.6590488057153554,0.5771599918037926,-0.3536657728297462,-0.36964083848210133,0.017588330277042968,0.4101906969059821,0.46633196825224094,3.1966266482758665,0.20968982025645352,-1.0832688429088466,-0.2901881007744104,0.819799068860265,2.4595918230799607,-0.48268182979148255,2.8965139805223146,0.5634104540353521,2.8370461170260968,1.5464329024539194 | 3,220 |
Glycosaminoglycan metabolism | 6 | 14 | 2.558538 | 0.010511 | Q8TB61,Q8NCH0,Q7LGA3,P54802,O43505,P06865 | Processes and pathways | Reactome Pathways | msigdb_reactome | 137,43,302,240,244,285 | 1600,244,285,1681,1606,786,614,240,302,43,137,2227,309,573 | -0.14976107776049186,1.4747593560996295,1.329137999738356,-0.1962091472678085,-0.14976107776049186,0.4242723854370574,0.6318674029638589,1.4867565983726359,1.2799015060822838,2.9063803252299736,2.1059164207950953,-0.4501643839012559,1.242739174664162,0.6996089005935843 | 3,220 |
Golgi cisterna membrane | 13 | 21 | 2.553328 | 0.01067 | Q10713,Q12893,P98194,Q96JB2,Q8NBN3,P51572,Q15363,Q9Y3A3,Q99523,Q10472,Q9Y6B6,Q9H4A6,O00461 | Localization | GO Cellular component | msigdb_gocc | 195,677,382,229,39,584,141,703,369,277,704,314,88 | 88,729,1606,584,382,1063,896,2124,277,195,677,141,39,3032,816,229,2227,369,314,703,704 | 2.4386350380760957,0.48029056583855095,-0.14976107776049186,0.6725969576878126,1.0410159526015372,0.16588167285776514,0.325039233943853,-0.4017197370823883,1.3658339237407737,1.7224537296137836,0.5496315311633986,2.0949263106223306,2.965312360286222,-1.1195734835314772,0.4101906969059821,1.534538665815881,-0.4501643839012559,1.092016293622401,1.2303064299473192,0.5219848971605708,0.5219848971605708 | 3,220 |
Muscle stiffness | 10 | 22 | 2.548902 | 0.010806 | P07602,Q9NZJ7,P23786,Q9BRK0,P53985,P49748,P11166,P33897,P00846,Q15392 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 67,359,168,399,473,433,497,633,25,29 | 2607,2464,25,2435,67,497,168,633,1089,433,1220,473,1465,1725,29,1640,1412,399,1673,694,359,782 | -0.6648079405015793,-0.5813222600056109,3.1776123860617123,-0.5647669902106163,2.625151948477759,0.8065529251182306,1.8373970276820892,0.6045715368978304,0.13650467332375438,0.9508178956967717,0.06244972498315363,0.8593782894230385,-0.07312611883137438,-0.21177118338905118,3.081835643844188,-0.16520434781562565,-0.04273894393938979,1.0153693117770466,-0.180686953630024,0.5358230652915174,1.1173718443197118,0.4383230465774212 | 3,220 |
Mitochondrial nucleotide transporter subfamily | 9 | 10 | 2.547393 | 0.010853 | P12236,Q70HW3,Q9H2D1,P12235,Q6NUK1,Q9HC21,P16260,Q9BSK2,P05141 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 480,11,107,235,625,533,217,348,664 | 696,664,235,480,217,625,11,348,107,533 | 0.5219848971605708,0.5634104540353521,1.4987330608256157,0.8462116178421202,1.5819939425106004,0.6182338533453158,3.6755062380906676,1.1426321922261868,2.2688006578891002,0.7532993971393909 | 3,220 |
Stimuli sensing channels | 7 | 11 | 2.546705 | 0.010875 | P51798,Q4KMQ2,Q9NW15,Q9C0H2,Q12797,P27105,P51790 | Processes and pathways | Reactome Pathways | msigdb_reactome | 160,654,694,51,559,407,511 | 407,1296,511,160,559,709,654,1568,51,1514,694 | 1.0025089619631318,0.017588330277042968,0.7799802251689579,1.9054783305621512,0.7130729829609895,0.5081168661324692,0.5771599918037926,-0.11899154943441288,2.807136845978207,-0.08837640269605082,0.5358230652915174 | 3,220 |
Mitochondrial membrane organization | 29 | 53 | 2.54537 | 0.010916 | Q9NVH1,P50542,Q13505,Q9P0J0,Q8IWA4,Q9Y5J6,P62072,P05141,P17152,Q8N8Q8,O60313,Q9NS69,Q9Y584,Q16891,O75431,Q5HYI7,P45880,Q6UXV4,O14737,Q9Y5J9,Q15070,Q9BUR5,O95202,Q9H3K2,P52789,P12235,O94826,Q5XKP0,Q9Y512 | Processes and pathways | GO Biological process | msigdb_gobp | 659,649,143,797,792,413,153,664,675,295,798,45,49,684,555,571,58,586,582,344,91,222,727,102,231,235,740,117,502 | 2076,582,798,555,740,1155,727,1837,664,1270,2677,2793,235,675,2505,2055,2185,2537,2538,58,2058,908,1076,649,231,153,1019,143,91,684,1009,1038,571,117,586,792,1039,1928,295,841,222,102,45,659,1050,797,1083,1761,1428,502,49,413,344 | -0.38565873026838904,0.6725969576878126,0.4101906969059821,0.7130729829609895,0.46633196825224094,0.09217774053922007,0.48029056583855095,-0.27442293885448277,0.5634104540353521,0.03257833492512616,-0.7154791723941134,-0.8009285846731938,1.4987330608256157,0.5496315311633986,-0.5979243699912032,-0.36964083848210133,-0.43397226707902753,-0.6145736537180316,-0.6145736537180316,2.6863034556568013,-0.36964083848210133,0.3107354423149406,0.15121046465169286,0.5771599918037926,1.5226240055116986,1.9840933186443066,0.1951211504020895,2.0839194517291406,2.417618705824693,0.5358230652915174,0.20968982025645352,0.18051850104213735,0.6996089005935843,2.2040841082583706,0.6725969576878126,0.4242723854370574,0.18051850104213735,-0.30599468976821914,1.3045641696350245,0.3819335469967939,1.5583068029385927,2.3116287576952588,2.8965139805223146,0.5771599918037926,0.18051850104213735,0.4242723854370574,0.15121046465169286,-0.22737331928668936,-0.04273894393938979,0.8065529251182306,2.8370461170260968,1.0025089619631318,1.155226944031845 | 3,220 |
Receptor | 14 | 37 | 2.54048 | 0.01107 | O00264,Q14108,O15118,P30825,O15173,Q9NS69,Q99523,O43731,Q8WTV0,Q9Y2I1,Q14739,P24390,Q9Y5M8,Q99720 | Functions | Protein Atlas Molecular function | protein_atlas_molecular_function | 255,101,135,71,76,45,369,52,54,216,57,27,380,63 | 255,3190,135,76,52,718,1005,2341,860,1461,2080,2405,536,425,801,1242,665,27,71,578,1384,2285,101,57,1922,965,54,2453,3033,369,1043,63,45,216,1236,380,2429 | 1.426560767391194,-2.4568040656609553,2.1168898459726213,2.522109081347491,2.7871316053248827,0.49421881017368724,0.20968982025645352,-0.5153789425131554,0.3535502000193913,-0.07312611883137438,-0.38565873026838904,-0.5482582308154097,0.7399180890945217,0.9637783554965194,0.4101906969059821,0.04753206007602352,0.5634104540353521,3.101086023493359,2.553171637047871,0.6861169405393601,-0.027601585489929144,-0.48268182979148255,2.3116287576952588,2.696447157783284,-0.30599468976821914,0.25319391829959953,2.7368859058038453,-0.5647669902106163,-1.1195734835314772,1.092016293622401,0.18051850104213735,2.665974910710302,2.8965139805223146,1.6056007727589223,0.06244972498315363,1.0538024802920216,-0.5482582308154097 | 3,220 |
Intrinsic component of plasma membrane | 43 | 79 | 2.5395 | 0.011101 | Q9NR28,P55061,P05067,Q99797,O15118,Q9BRK0,P51790,Q9Y4G8,O60637,P10586,P05141,P20645,P27105,Q08722,Q00325,P17152,O00400,O00560,P05023,P11279,Q13641,Q9H1Z9,Q8WTV0,P20020,O43657,P35613,Q99805,P30825,Q9H2J7,P51572,Q9Y639,O95864,P16615,P27824,Q92542,P53985,Q12907,Q9UIQ6,O96005,P12235,P11166,P10321,O00264 | Localization | GO Cellular component | msigdb_gocc | 386,637,636,384,135,399,511,274,15,536,664,665,407,547,676,675,41,541,424,425,301,179,54,697,66,578,198,71,457,584,330,583,342,471,735,473,731,223,361,235,497,510,255 | 769,255,41,541,3190,135,2461,820,66,1322,15,583,361,1005,728,424,987,636,664,2341,1602,2793,510,536,497,425,801,235,342,675,2934,697,665,407,471,71,1436,578,803,2244,584,511,473,1113,922,637,1384,676,1093,547,731,2285,301,2414,1922,2323,1789,2164,937,979,54,735,384,198,399,901,3219,2456,179,1736,457,1673,386,2297,223,845,2427,274,330 | 0.4383230465774212,1.426560767391194,2.926074846462015,0.7265093315527947,-2.4568040656609553,2.1168898459726213,-0.5813222600056109,0.39607780869964226,2.635378540961516,0.0025618247362464894,3.5312195393485935,0.6725969576878126,1.104706025521293,0.20968982025645352,0.48029056583855095,0.9637783554965194,0.22422470806964243,0.5908803010183907,0.5634104540353521,-0.5153789425131554,-0.14976107776049186,-0.8009285846731938,0.7799802251689579,0.7399180890945217,0.8065529251182306,0.9637783554965194,0.4101906969059821,1.4987330608256157,1.155226944031845,0.5496315311633986,-0.9580154630503087,0.5219848971605708,0.5634104540353521,1.0025089619631318,0.8593782894230385,2.553171637047871,-0.05791371087003406,0.6861169405393601,0.4101906969059821,-0.4664008031269134,0.6725969576878126,0.7799802251689579,0.8593782894230385,0.12176409384605623,0.2963992009112666,0.5908803010183907,-0.027601585489929144,0.5496315311633986,0.13650467332375438,0.7265093315527947,0.48029056583855095,-0.48268182979148255,1.2799015060822838,-0.5482582308154097,-0.30599468976821914,-0.49900777230689414,-0.243015814924118,-0.417824150950574,0.2820303246081004,0.23872600947530984,2.7368859058038453,0.48029056583855095,1.0410159526015372,1.7108556718152539,1.0153693117770466,0.325039233943853,-10.499224614509929,-0.5647669902106163,1.803109914230054,-0.21177118338905118,0.8987214683111048,-0.180686953630024,1.0410159526015372,-0.48268182979148255,1.5583068029385927,0.3819335469967939,-0.5482582308154097,1.3780223384827002,1.1928708296276316 | 3,220 |
Morphological abnormality of the pyramidal tract | 8 | 24 | 2.537716 | 0.011158 | Q9Y4P3,P35637,O75298,O00400,Q9Y619,O95831,Q9H9P8,P00846 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 418,260,448,41,142,55,184,25 | 41,1185,448,2944,1576,55,25,497,1108,633,1243,260,2443,2686,1442,991,1065,1095,1921,184,1370,2397,418,142 | 2.926074846462015,0.07733154678623776,0.9117840142979674,-0.9757397882754897,-0.13435689396020284,2.7166936523547114,3.1776123860617123,0.8065529251182306,0.12176409384605623,0.6045715368978304,0.04753206007602352,1.4144582543439532,-0.5647669902106163,-0.7154791723941134,-0.05791371087003406,0.22422470806964243,0.16588167285776514,0.13650467332375438,-0.30599468976821914,1.7916438703696143,-0.012501405263775458,-0.5317956557309711,0.9896237665665621,2.0949263106223306 | 3,220 |
Sterol biosynthetic process | 12 | 27 | 2.525226 | 0.011562 | Q15125,P48449,Q16850,Q14534,Q9H2C2,Q15800,O75845,P54646,Q6P1A2,Q14739,P16435,Q15392 | Processes and pathways | GO Biological process | msigdb_gobp | 3,261,133,462,238,61,470,373,410,57,347,29 | 3110,470,1323,1157,1212,894,347,1275,2538,261,2123,373,3048,2253,2947,462,57,3,2543,29,2544,61,133,410,238,476,1676 | -1.3805716198597155,0.8593782894230385,0.0025618247362464894,0.09217774053922007,0.06244972498315363,0.325039233943853,1.1426321922261868,0.03257833492512616,-0.6145736537180316,1.4144582543439532,-0.4017197370823883,1.0665646357789607,-1.156115218044601,-0.4664008031269134,-0.9757397882754897,0.8856330846497343,2.696447157783284,4.059475865189276,-0.6145736537180316,3.081835643844188,-0.6145736537180316,2.6761460554500984,2.1278466494928105,1.0025089619631318,1.4987330608256157,0.8593782894230385,-0.180686953630024 | 3,220 |
Abnormal biliary tract morphology | 8 | 23 | 2.514579 | 0.011917 | P07602,Q10713,Q14108,Q9NZJ7,P04062,Q5XKP0,Q14739,Q9NSD9 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 67,195,101,359,140,117,57,388 | 1347,1432,140,67,576,833,1942,2407,2058,649,1219,195,1501,101,57,117,2968,794,388,359,446,1761,2175 | -0.012501405263775458,-0.05791371087003406,2.0949263106223306,2.625151948477759,0.6861169405393601,0.3819335469967939,-0.32184297973986525,-0.5482582308154097,-0.36964083848210133,0.5771599918037926,0.06244972498315363,1.7224537296137836,-0.08837640269605082,2.3116287576952588,2.696447157783284,2.2040841082583706,-1.011355668757608,0.4242723854370574,1.0410159526015372,1.1173718443197118,0.9248208500595174,-0.22737331928668936,-0.417824150950574 | 3,220 |
Organelle inner membrane | 117 | 260 | 2.510628 | 0.012052 | O43676,P03886,Q5SNT2,Q9H061,Q70HW3,Q9P0S2,Q9HC21,Q8IYU8,O14949,P00846,O60830,P62995,O95139,O75844,Q9Y6C9,Q9Y584,O75964,O75431,Q5HYI7,O95831,Q14739,Q99720,Q96ER9,Q9H2V7,Q6UXV4,Q9BYC9,O75027,Q99595,O14548,Q9NX14,Q9HD33,Q6P4A7,Q15070,Q9H300,Q7Z7F7,O14925,O75251,Q9H3K2,Q9UBX3,Q9H2D1,Q6NUK1,Q5XKP0,Q9H1E5,P21912,O75947,Q9H2W6,Q9Y2R0,Q9NVH1,Q9Y619,Q13505,P62072,Q96CU9,P05141,O95167,Q13423,Q9H4I9,P82933,P17152,Q00325,P23786,Q8N442,Q86Y39,Q567V2,P23396,Q16891,Q9H9P8,P14406,Q10713,Q9BQT8,Q9UDW1,Q9Y241,P13073,P16260,Q9BUR5,Q8NI60,P12235,P22695,Q16134,O95674,P53701,O75306,Q8WUK0,Q9UDX5,O75208,Q8N8Q8,Q9NPL8,Q99643,Q7KZN9,Q9BYD1,Q9Y5J9,Q9Y6M9,Q9Y6N1,Q9BSK2,Q8IXM6,Q8NBN7,Q9UH99,Q9UG56,Q96AQ8,Q9NVI7,Q9BUB7,Q9Y5J6,Q6DKK2,O96008,P49748,Q9P015,P24539,O43772,Q9NVS2,Q9UJZ1,P56385,P50402,P12236,Q96NB2,Q9BRJ2,Q96IX5,Q9Y512,Q5T9A4 | Localization | GO Cellular component | msigdb_gocc | 1,7,523,9,11,16,533,530,22,25,26,546,544,40,566,49,47,555,571,55,57,63,581,70,586,598,81,84,592,613,612,607,91,610,98,97,600,102,103,107,625,117,121,632,630,642,139,659,142,143,153,155,664,663,161,165,163,675,676,168,688,172,178,681,684,184,188,195,203,204,211,212,217,222,226,235,245,250,271,280,283,291,293,294,295,308,318,332,339,344,345,346,348,356,368,370,389,392,412,411,413,428,423,433,436,455,458,469,477,482,481,480,486,494,499,502,506 | 1710,592,1484,97,22,821,1548,1,458,1151,2673,798,26,81,294,600,283,1907,555,1457,1908,2179,3118,1154,40,859,630,47,2372,919,544,663,2374,1133,727,1398,929,271,55,2532,423,849,25,7,1838,664,1269,2710,1602,1522,2881,2677,800,2146,3022,235,480,2814,212,188,2754,1085,217,675,880,2216,824,1007,632,2504,245,759,681,168,455,2437,3195,1215,1057,906,1436,882,803,2537,1188,1111,2718,850,962,2996,2083,433,2855,481,2150,1328,3112,836,280,1138,2839,1246,827,482,1304,153,546,1847,2061,1221,2959,1439,1658,1385,163,676,1093,948,195,2064,1443,2511,3198,161,143,1691,3185,57,91,250,2125,2448,1614,684,1009,1038,178,571,1224,2664,523,506,117,428,625,1168,607,2594,586,700,11,332,2385,98,898,172,356,530,3138,688,295,2693,368,1227,1120,226,291,841,2572,1391,1392,392,1414,155,3018,581,1416,2097,499,486,1567,84,1043,318,63,1315,855,203,494,2698,348,875,1733,411,222,598,339,2486,2731,2037,9,121,107,70,642,610,102,165,1178,1027,1179,2624,184,2294,533,612,1049,308,878,1207,3194,2919,659,412,469,1596,613,1050,2171,436,1208,797,16,103,204,293,389,370,845,477,211,1761,2559,1968,139,2074,2301,2703,2212,2213,1428,502,49,413,344,142,566,345,346,2046 | 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| 3,220 |
metalloprotease | 9 | 28 | 2.502837 | 0.01232 | O43847,P42892,Q10713,O75844,Q7Z2K6,P22695,P55786,Q9NZ08,Q9UIQ6 | Functions | Panther Protein class | panther_protein_class | 282,130,195,40,114,245,86,152,223 | 282,1457,40,2432,1005,3166,1242,245,2945,1057,130,1406,1279,86,195,790,886,114,764,1732,1567,384,1124,1149,2787,152,223,1428 | 1.329137999738356,-0.07312611883137438,2.9359031050233613,-0.5647669902106163,0.20968982025645352,-1.9013859901122099,0.04753206007602352,1.4747593560996295,-0.9757397882754897,0.16588167285776514,2.138786894309507,-0.04273894393938979,0.03257833492512616,2.449120847556878,1.7224537296137836,0.4242723854370574,0.33931075924719056,2.2257201697391493,0.4523428510935623,-0.21177118338905118,-0.11899154943441288,1.0410159526015372,0.12176409384605623,0.10698851923772369,-0.7837372383934156,1.9952538492017513,1.5583068029385927,-0.04273894393938979 | 3,220 |
Cis golgi network | 6 | 17 | 2.499705 | 0.01243 | Q9NPR9,O95249,O43731,O00461,P24390,Q8TBA6 | Localization | GO Cellular component | msigdb_gocc | 69,175,52,88,27,221 | 88,2834,52,175,27,2345,595,382,896,1559,1167,221,3032,2261,229,69,781 | 2.4386350380760957,-0.8354661427807923,2.7871316053248827,1.803109914230054,3.101086023493359,-0.5153789425131554,0.6590488057153554,1.0410159526015372,0.325039233943853,-0.11899154943441288,0.09217774053922007,1.5583068029385927,-1.1195734835314772,-0.4664008031269134,1.534538665815881,2.6149113753676136,0.4383230465774212 | 3,220 |
Rhizomelia | 8 | 13 | 2.499425 | 0.01244 | Q03164,Q15125,Q7RTS9,O75718,Q9BV10,Q14739,Q9UBM7,Q15392 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 225,3,328,518,182,57,476,29 | 957,567,2962,518,1404,2472,225,57,3,29,328,182,476 | 0.25319391829959953,0.6996089005935843,-1.011355668757608,0.7666533960815253,-0.04273894393938979,-0.5813222600056109,1.5464329024539194,2.696447157783284,4.059475865189276,3.081835643844188,1.1928708296276316,1.7916438703696143,0.8593782894230385 | 3,220 |
Sterol binding | 6 | 16 | 2.493419 | 0.012652 | O95772,Q14108,O15118,P35610,P45880,P21796 | Functions | GO Molecular function | msigdb_gomf | 128,101,135,396,58,28 | 135,3110,1323,128,2897,28,1213,2081,394,396,58,1190,101,1860,1734,1045 | 2.1168898459726213,-1.3805716198597155,0.0025618247362464894,2.149710642995687,-0.9051717595444062,3.0914668286417912,0.06244972498315363,-0.38565873026838904,1.0153693117770466,1.0153693117770466,2.6863034556568013,0.07733154678623776,2.3116287576952588,-0.27442293885448277,-0.21177118338905118,0.18051850104213735 | 3,220 |
Blindness | 17 | 77 | 2.489882 | 0.012779 | P51798,O43676,Q86SQ9,P07602,P53701,O75306,P03886,Q9Y6M9,Q9H6K4,Q86Y39,O43505,Q9NPL8,Q9NZ08,P00846,Q96CU9,P06865,P50897 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 160,1,257,67,280,283,7,345,10,172,244,308,152,25,155,285,31 | 1709,1653,1521,244,1,1802,1486,600,283,1907,1908,2634,1871,2532,3051,25,7,2709,2434,285,67,1681,1271,2932,614,527,2216,632,2504,3195,1215,2467,633,2737,2186,2407,1058,2120,1354,2855,2440,31,160,1220,280,2958,1817,1116,2382,3055,560,1954,2690,257,172,2324,3138,680,1040,1023,1334,1476,155,1070,1336,2784,1733,10,3077,308,1515,613,152,359,1208,2106,345 | -0.21177118338905118,-0.180686953630024,-0.10366479969187105,1.4747593560996295,4.194747446409669,-0.2586989329734473,-0.08837640269605082,0.6454723370713444,1.329137999738356,-0.30599468976821914,-0.30599468976821914,-0.681649331993938,-0.2901881007744104,-0.6145736537180316,-1.174476216167904,3.1776123860617123,3.869760435421595,-0.7324683402938643,-0.5647669902106163,1.329137999738356,2.625151948477759,-0.1962091472678085,0.03257833492512616,-0.9580154630503087,0.6318674029638589,0.7532993971393909,-0.4501643839012559,0.6045715368978304,-0.5979243699912032,-2.5516940759544804,0.06244972498315363,-0.5813222600056109,0.6045715368978304,-0.7495074930568375,-0.43397226707902753,-0.5482582308154097,0.16588167285776514,-0.4017197370823883,-0.012501405263775458,-0.8528131358802458,-0.5647669902106163,3.072192431575852,1.9054783305621512,0.06244972498315363,1.3536237939644702,-0.9935197104671422,-0.2586989329734473,0.12176409384605623,-0.5317956557309711,-1.174476216167904,0.7130729829609895,-0.32184297973986525,-0.7154791723941134,1.426560767391194,1.8259864180767964,-0.49900777230689414,-1.5551706483297403,0.5496315311633986,0.18051850104213735,0.1951211504020895,0.0025618247362464894,-0.07312611883137438,1.9729153800776973,0.16588167285776514,0.0025618247362464894,-0.7837372383934156,-0.21177118338905118,3.8084575200102933,-1.2113809723326867,1.242739174664162,-0.08837640269605082,0.6454723370713444,1.9952538492017513,1.1173718443197118,0.07733154678623776,-0.38565873026838904,1.155226944031845 | 3,220 |
Vacuolar lumen | 19 | 61 | 2.487431 | 0.012867 | Q8NHP8,P04062,P10619,P11117,P06865,P50897,P06280,Q9BTY2,P04066,Q9UMR5,Q13510,P07602,O14773,Q14108,P38435,Q9H7Z7,Q9NZJ7,P54802,Q8IV08 | Localization | GO Cellular component | msigdb_gocc | 136,140,20,279,285,31,284,292,300,56,59,67,214,101,230,358,359,240,126 | 541,660,214,1347,1157,140,300,284,285,2956,930,67,1681,1270,362,20,279,2274,2534,647,786,614,527,2315,2816,230,760,2348,2614,31,1844,2123,1090,1815,240,2443,1383,1190,911,1584,3199,2380,653,59,101,2976,126,1956,136,1203,1510,2391,526,292,1541,3087,358,1181,359,56,2528 | 0.7265093315527947,0.5634104540353521,1.6173742844059265,-0.012501405263775458,0.09217774053922007,2.0949263106223306,1.2799015060822838,1.329137999738356,1.329137999738356,-0.9935197104671422,0.2820303246081004,2.625151948477759,-0.1962091472678085,0.03257833492512616,1.104706025521293,3.2722229339827167,1.3536237939644702,-0.48268182979148255,-0.6145736537180316,0.5771599918037926,0.4242723854370574,0.6318674029638589,0.7532993971393909,-0.49900777230689414,-0.8181714233751796,1.5226240055116986,0.4523428510935623,-0.5153789425131554,-0.6648079405015793,3.072192431575852,-0.27442293885448277,-0.4017197370823883,0.13650467332375438,-0.2586989329734473,1.4867565983726359,-0.5647669902106163,-0.027601585489929144,0.07733154678623776,0.3107354423149406,-0.13435689396020284,-2.899313850240335,-0.5317956557309711,0.5771599918037926,2.6863034556568013,2.3116287576952588,-1.029248107858703,2.160617957746634,-0.32184297973986525,2.1059164207950953,0.07733154678623776,-0.08837640269605082,-0.5317956557309711,0.7666533960815253,1.3168621387496977,-0.10366479969187105,-1.2299257497204847,1.1173718443197118,0.09217774053922007,1.1173718443197118,2.7065772080315718,-0.5979243699912032 | 3,220 |
Peptide binding | 14 | 71 | 2.485219 | 0.012947 | Q9Y287,P42892,Q9UIQ6,Q03518,Q9Y584,O43731,Q8WTV0,Q9UHB9,Q9NZ08,P55786,O14773,P24390,Q15392,O00264 | Functions | GO Molecular function | msigdb_gomf | 129,130,223,264,49,52,54,151,152,86,214,27,29,255 | 904,255,819,1711,214,2562,52,1322,1397,1550,1488,740,728,1874,1435,510,1242,1942,2536,27,3070,2147,2505,861,2345,1353,2278,1075,130,2987,2586,1609,649,909,2683,1278,86,2060,1303,1079,2473,264,1440,2867,2822,2570,2065,3119,746,29,886,815,54,1024,1146,1101,2069,900,3086,1124,2623,358,289,2488,152,151,941,223,129,1183,49 | 0.3107354423149406,1.426560767391194,0.39607780869964226,-0.21177118338905118,1.6173742844059265,-0.6312704485557797,2.7871316053248827,0.0025618247362464894,-0.04273894393938979,-0.11899154943441288,-0.08837640269605082,0.46633196825224094,0.48029056583855095,-0.2901881007744104,-0.05791371087003406,0.7799802251689579,0.04753206007602352,-0.32184297973986525,-0.6145736537180316,3.101086023493359,-1.2113809723326867,-0.417824150950574,-0.5979243699912032,0.3535502000193913,-0.5153789425131554,-0.012501405263775458,-0.48268182979148255,0.15121046465169286,2.138786894309507,-1.0471974781596876,-0.6480150957535664,-0.14976107776049186,0.5771599918037926,0.3107354423149406,-0.7154791723941134,0.03257833492512616,2.449120847556878,-0.36964083848210133,0.017588330277042968,0.15121046465169286,-0.5813222600056109,1.3901891347163047,-0.05791371087003406,-0.8702128004514436,-0.8181714233751796,-0.6312704485557797,-0.36964083848210133,-1.4188888944064315,0.46633196825224094,3.081835643844188,0.33931075924719056,0.4101906969059821,2.7368859058038453,0.1951211504020895,0.10698851923772369,0.13650467332375438,-0.36964083848210133,0.325039233943853,-1.2299257497204847,0.12176409384605623,-0.6648079405015793,1.1173718443197118,1.329137999738356,-0.5813222600056109,1.9952538492017513,2.0063970395336046,0.2820303246081004,1.5583068029385927,2.149710642995687,0.09217774053922007,2.8370461170260968 | 3,220 |
Sphingolipid metabolism integrated pathway | 6 | 9 | 2.482848 | 0.013034 | P27544,Q16739,O15269,O95470,Q96G23,Q13510 | Processes and pathways | WikiPathways | msigdb_wp | 519,561,422,148,154,59 | 422,1267,148,519,616,59,561,154,1207 | 0.9637783554965194,0.03257833492512616,2.028631668550595,0.7666533960815253,0.6318674029638589,2.6863034556568013,0.7130729829609895,1.9840933186443066,0.07733154678623776 | 3,220 |
Sphingolipid metabolism overview | 6 | 9 | 2.482848 | 0.013034 | P27544,Q16739,O15269,O95470,Q96G23,Q13510 | Processes and pathways | WikiPathways | msigdb_wp | 519,561,422,148,154,59 | 422,1267,148,519,616,59,561,154,1207 | 0.9637783554965194,0.03257833492512616,2.028631668550595,0.7666533960815253,0.6318674029638589,2.6863034556568013,0.7130729829609895,1.9840933186443066,0.07733154678623776 | 3,220 |
Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen | 12 | 28 | 2.474276 | 0.013351 | P09601,P13674,Q8NB78,Q16850,Q14534,P30519,Q9BU89,Q6UW02,Q12797,O75845,P16435,Q15800 | Functions | GO Molecular function | msigdb_gomf | 576,577,580,133,462,14,145,241,559,470,347,61 | 661,1626,1210,959,2812,470,1031,583,1376,576,577,347,14,2249,1817,559,462,61,133,838,1118,241,2127,580,145,1449,1574,2702 | 0.5634104540353521,-0.16520434781562565,0.06244972498315363,0.25319391829959953,-0.8181714233751796,0.8593782894230385,0.18051850104213735,0.6725969576878126,-0.027601585489929144,0.6861169405393601,0.6861169405393601,1.1426321922261868,3.5403143393794037,-0.4664008031269134,-0.2586989329734473,0.7130729829609895,0.8856330846497343,2.6761460554500984,2.1278466494928105,0.3819335469967939,0.12176409384605623,1.4867565983726359,-0.4017197370823883,0.6861169405393601,2.0618552309246474,-0.05791371087003406,-0.11899154943441288,-0.7154791723941134 | 3,220 |
Mitochondrial carrier protein [IPR002067] | 10 | 13 | 2.473304 | 0.013387 | P12236,Q96H78,Q9BQT8,P12235,Q6NUK1,Q9HC21,Q9UJS0,P16260,P05141,O43808 | Sequence | InterPro Family | interpro_family | 480,73,203,235,625,533,845,217,664,696 | 696,1154,664,235,480,217,836,625,73,203,1027,533,845 | 0.5219848971605708,0.09217774053922007,0.5634104540353521,1.4987330608256157,0.8462116178421202,1.5819939425106004,0.3819335469967939,0.6182338533453158,2.5428318406638946,1.6759461511432516,0.1951211504020895,0.7532993971393909,0.3819335469967939 | 3,220 |
Transport vesicle | 34 | 95 | 2.463678 | 0.013752 | P05067,Q15363,O15260,O43760,Q96A57,O14653,Q15907,P24390,P20645,O60499,O75340,P50897,O43752,Q9UI14,P11279,O95249,O43731,Q9GZM5,Q9Y6B6,Q9UHD1,O76024,P20020,Q9Y3B3,P49755,O00461,Q92542,Q8TBA6,P04439,Q9BT78,Q9NR31,P61026,Q99523,P10321,P51790 | Localization | GO Cellular component | msigdb_gocc | 636,141,268,269,147,393,408,27,665,158,662,31,290,431,425,175,52,183,704,573,316,697,327,595,88,735,221,728,99,495,623,369,510,511 | 1801,88,1014,393,830,1485,268,1763,2461,52,2654,290,269,158,3108,2810,662,1084,2812,316,1490,175,1744,3109,728,636,1435,2793,510,425,801,697,1135,665,27,2115,1716,1216,1552,2472,595,31,1814,1496,1497,511,826,2588,2866,2247,1657,1979,1078,623,1720,1114,2777,2721,910,2740,913,1532,2570,1883,1776,2199,1886,2724,2414,141,1952,408,2288,1473,221,735,888,147,369,99,752,183,1000,1176,495,1367,2172,1012,573,431,2108,327,2430,704,1053 | -0.2586989329734473,2.4386350380760957,0.1951211504020895,1.0153693117770466,0.3819335469967939,-0.08837640269605082,1.3780223384827002,-0.243015814924118,-0.5813222600056109,2.7871316053248827,-0.6985396234928575,1.3168621387496977,1.3780223384827002,1.9505070056529454,-1.3615133499639909,-0.8181714233751796,0.5634104540353521,0.13650467332375438,-0.8181714233751796,1.2178508611985153,-0.08837640269605082,1.803109914230054,-0.22737331928668936,-1.3615133499639909,0.48029056583855095,0.5908803010183907,-0.05791371087003406,-0.8009285846731938,0.7799802251689579,0.9637783554965194,0.4101906969059821,0.5219848971605708,0.10698851923772369,0.5634104540353521,3.101086023493359,-0.4017197370823883,-0.21177118338905118,0.06244972498315363,-0.11899154943441288,-0.5813222600056109,0.6590488057153554,3.072192431575852,-0.2586989329734473,-0.08837640269605082,-0.08837640269605082,0.7799802251689579,0.39607780869964226,-0.6480150957535664,-0.8702128004514436,-0.4664008031269134,-0.180686953630024,-0.3377332475042113,0.15121046465169286,0.6182338533453158,-0.21177118338905118,0.12176409384605623,-0.7837372383934156,-0.7324683402938643,0.3107354423149406,-0.7495074930568375,0.3107354423149406,-0.10366479969187105,-0.6312704485557797,-0.2901881007744104,-0.243015814924118,-0.43397226707902753,-0.2901881007744104,-0.7324683402938643,-0.5482582308154097,2.0949263106223306,-0.32184297973986525,1.0025089619631318,-0.48268182979148255,-0.07312611883137438,1.5583068029385927,0.48029056583855095,0.33931075924719056,2.039723240709385,1.092016293622401,2.354208142416853,0.46633196825224094,1.7916438703696143,0.22422470806964243,0.09217774053922007,0.819799068860265,-0.012501405263775458,-0.417824150950574,0.20968982025645352,0.6996089005935843,0.9637783554965194,-0.38565873026838904,1.2053723631183846,-0.5482582308154097,0.5219848971605708,0.18051850104213735 | 3,220 |
Glycoprotein metabolic process | 21 | 72 | 2.460214 | 0.013885 | Q9Y287,Q86SQ9,O60858,O15118,O60502,P35610,Q10472,Q9BXS4,Q9NQX7,Q8N4A0,Q8NCH0,Q7LGA3,Q9NRB3,Q9BV10,Q9H4A6,Q9HC07,Q99805,Q8NBI6,Q86YN1,Q96JB2,O43505 | Processes and pathways | GO Biological process | msigdb_gobp | 129,257,259,135,270,396,277,149,289,32,43,302,309,182,314,197,198,333,79,229,244 | 619,135,2048,244,673,270,959,2674,1349,259,662,1492,945,2273,1272,1606,2737,396,2017,488,2250,910,2884,1817,1193,896,2124,277,1356,2662,2023,1167,2663,3056,2359,302,1820,1858,257,79,32,333,43,816,735,3033,1446,229,2227,3000,198,1123,417,182,149,2456,1176,1318,1830,314,2961,3077,197,289,309,554,1937,1797,573,129,3080,2653 | 0.6182338533453158,2.1168898459726213,-0.36964083848210133,1.4747593560996295,0.5496315311633986,1.3780223384827002,0.25319391829959953,-0.7154791723941134,-0.012501405263775458,1.4144582543439532,0.5634104540353521,-0.08837640269605082,0.2676286265840488,-0.48268182979148255,0.03257833492512616,-0.14976107776049186,-0.7495074930568375,1.0153693117770466,-0.3536657728297462,0.819799068860265,-0.4664008031269134,0.3107354423149406,-0.8876655391405662,-0.2586989329734473,0.07733154678623776,0.325039233943853,-0.4017197370823883,1.3658339237407737,-0.012501405263775458,-0.6985396234928575,-0.3536657728297462,0.09217774053922007,-0.6985396234928575,-1.174476216167904,-0.5153789425131554,1.2799015060822838,-0.2586989329734473,-0.27442293885448277,1.426560767391194,2.5013284307582575,3.072192431575852,1.180346153859077,2.9063803252299736,0.4101906969059821,0.48029056583855095,-1.1195734835314772,-0.05791371087003406,1.534538665815881,-0.4501643839012559,-1.0652042358274294,1.7108556718152539,0.12176409384605623,0.9896237665665621,1.7916438703696143,2.0175229570018764,-0.5647669902106163,0.09217774053922007,0.017588330277042968,-0.2586989329734473,1.2303064299473192,-0.9935197104671422,-1.2113809723326867,1.7224537296137836,1.329137999738356,1.242739174664162,0.7265093315527947,-0.30599468976821914,-0.243015814924118,0.6996089005935843,2.149710642995687,-1.2113809723326867,-0.681649331993938 | 3,220 |
Variable expressivity | 11 | 80 | 2.450094 | 0.014282 | Q8NI60,P00374,Q15125,P07602,P03886,Q9H061,Q70HW3,Q9NR77,O95470,Q13510,Q13509 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 226,191,3,67,7,9,11,243,148,59,159 | 2008,1801,1292,1349,2372,1155,1350,148,191,849,1432,7,772,2435,438,67,1873,2986,960,497,527,1186,905,2657,1552,1058,3152,1218,850,2348,2798,556,2799,1220,1380,2443,2444,990,2958,1530,2740,1193,1725,159,59,866,1885,1164,2023,3055,3,1194,2383,1038,679,607,1640,11,257,226,1040,816,1231,1259,1103,736,9,1318,2624,3077,658,243,780,359,2526,635,1761,2074,782,1428 | -0.3536657728297462,-0.2586989329734473,0.017588330277042968,-0.012501405263775458,-0.5317956557309711,0.09217774053922007,-0.012501405263775458,2.028631668550595,1.7340326951249647,0.36775773642059567,-0.05791371087003406,3.869760435421595,0.4383230465774212,-0.5647669902106163,0.937832102041449,2.625151948477759,-0.2901881007744104,-1.0471974781596876,0.25319391829959953,0.8065529251182306,0.7532993971393909,0.07733154678623776,0.3107354423149406,-0.6985396234928575,-0.11899154943441288,0.16588167285776514,-1.7152768494821569,0.06244972498315363,0.36775773642059567,-0.5153789425131554,-0.8009285846731938,0.7130729829609895,-0.8009285846731938,0.06244972498315363,-0.027601585489929144,-0.5647669902106163,-0.5647669902106163,0.22422470806964243,-0.9935197104671422,-0.10366479969187105,-0.7495074930568375,0.07733154678623776,-0.21177118338905118,1.9167621647102622,2.6863034556568013,0.3535502000193913,-0.2901881007744104,0.09217774053922007,-0.3536657728297462,-1.174476216167904,4.059475865189276,0.07733154678623776,-0.5317956557309711,0.18051850104213735,0.5496315311633986,0.6454723370713444,-0.16520434781562565,3.6755062380906676,1.426560767391194,1.5464329024539194,0.18051850104213735,0.4101906969059821,0.06244972498315363,0.04753206007602352,0.13650467332375438,0.48029056583855095,3.817243530612087,0.017588330277042968,-0.6648079405015793,-1.2113809723326867,0.5771599918037926,1.4867565983726359,0.4383230465774212,1.1173718443197118,-0.5979243699912032,0.6045715368978304,-0.22737331928668936,-0.36964083848210133,0.4383230465774212,-0.04273894393938979 | 3,220 |
Cholesterol metabolism with bloch and kandutschrussell pathways | 10 | 25 | 2.448894 | 0.01433 | Q15125,P48449,Q16850,Q9BWD1,Q14534,P35610,Q15800,O75845,Q14739,Q15392 | Processes and pathways | WikiPathways | msigdb_wp | 3,261,133,35,462,396,61,470,57,29 | 661,1152,470,1628,2864,583,894,1088,396,1275,261,2120,3048,2253,2947,462,57,3,2543,29,2544,61,133,35,476 | 0.5634104540353521,0.09217774053922007,0.8593782894230385,-0.16520434781562565,-0.8702128004514436,0.6725969576878126,0.325039233943853,0.13650467332375438,1.0153693117770466,0.03257833492512616,1.4144582543439532,-0.4017197370823883,-1.156115218044601,-0.4664008031269134,-0.9757397882754897,0.8856330846497343,2.696447157783284,4.059475865189276,-0.6145736537180316,3.081835643844188,-0.6145736537180316,2.6761460554500984,2.1278466494928105,3.023794631549293,0.8593782894230385 | 3,220 |
Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins | 24 | 70 | 2.444754 | 0.014495 | O43676,P03886,Q9P0S2,O14949,P00846,O75306,O95139,Q8N8Q8,Q86Y39,O75964,Q9NPL8,Q99643,P24539,Q9UDW1,P13073,O14548,Q9NX14,Q9Y6M9,Q9Y6N1,P56385,O75251,P22695,P21912,Q16134 | Processes and pathways | Reactome Pathways | msigdb_reactome | 1,7,16,22,25,283,544,295,172,47,308,318,455,204,212,592,613,345,346,482,600,245,632,250 | 1710,592,1484,22,1548,1,1151,2673,600,283,1907,1908,859,630,47,544,663,2374,1133,1398,2532,849,25,7,1269,1522,800,2146,212,2564,2754,1085,2216,824,632,245,455,2437,3195,1215,1057,882,2821,2718,2996,2855,1328,1246,482,2064,250,2448,1614,172,3138,295,1040,318,855,1205,1733,1178,308,613,1208,797,16,204,345,346 | -0.21177118338905118,0.6590488057153554,-0.08837640269605082,3.2155945533343884,-0.11899154943441288,4.194747446409669,0.09217774053922007,-0.7154791723941134,0.6454723370713444,1.329137999738356,-0.30599468976821914,-0.30599468976821914,0.3535502000193913,0.6045715368978304,2.8370461170260968,0.7265093315527947,0.5634104540353521,-0.5317956557309711,0.10698851923772369,-0.04273894393938979,-0.6145736537180316,0.36775773642059567,3.1776123860617123,3.869760435421595,0.03257833492512616,-0.10366479969187105,0.4101906969059821,-0.417824150950574,1.6291279725959298,-0.6312704485557797,-0.7665970008859604,0.13650467332375438,-0.4501643839012559,0.39607780869964226,0.6045715368978304,1.4747593560996295,0.8987214683111048,-0.5647669902106163,-2.5516940759544804,0.06244972498315363,0.16588167285776514,0.33931075924719056,-0.8181714233751796,-0.7324683402938643,-1.0652042358274294,-0.8528131358802458,0.0025618247362464894,0.04753206007602352,0.8462116178421202,-0.36964083848210133,1.4507021690856339,-0.5647669902106163,-0.14976107776049186,1.8259864180767964,-1.5551706483297403,1.3045641696350245,0.18051850104213735,1.2178508611985153,0.36775773642059567,0.07733154678623776,-0.21177118338905118,0.09217774053922007,1.242739174664162,0.6454723370713444,0.07733154678623776,0.4242723854370574,3.476430925767484,1.6759461511432516,1.155226944031845,1.155226944031845 | 3,220 |
Carboxylic acid transport | 13 | 33 | 2.443891 | 0.01453 | O60831,P07602,Q96NB2,P30825,Q9NZJ7,Q9H2J7,Q9UBX3,Q9H2D1,Q9BQT8,Q9NP80,Q9Y619,P53985,Q15041 | Processes and pathways | GO Biological process | msigdb_gobp | 478,67,486,71,359,457,103,107,203,174,142,473,505 | 2705,478,1154,509,929,3004,2341,67,719,833,988,71,2244,836,473,922,1093,505,976,1922,1507,486,203,107,1736,457,1027,1179,174,359,103,845,142 | -0.7324683402938643,0.8462116178421202,0.09217774053922007,0.7799802251689579,0.2820303246081004,-1.0832688429088466,-0.5153789425131554,2.625151948477759,0.49421881017368724,0.3819335469967939,0.22422470806964243,2.553171637047871,-0.4664008031269134,0.3819335469967939,0.8593782894230385,0.2963992009112666,0.13650467332375438,0.7932800225164705,0.23872600947530984,-0.30599468976821914,-0.08837640269605082,0.833018588532747,1.6759461511432516,2.2688006578891002,-0.21177118338905118,0.8987214683111048,0.1951211504020895,0.09217774053922007,1.8145574051151347,1.1173718443197118,2.300945191798539,0.3819335469967939,2.0949263106223306 | 3,220 |
Amyloid precursor protein metabolic process | 8 | 22 | 2.442966 | 0.014567 | Q9Y287,O75298,P35610,Q9NQC3,O95197,P62942,Q9NQX7,Q15392 | Processes and pathways | GO Biological process | msigdb_gobp | 129,448,396,306,23,286,289,29 | 448,23,1602,2115,396,595,908,286,2824,2570,1020,1066,29,467,735,1446,1042,795,306,289,1937,129 | 0.9117840142979674,3.2061163777469694,-0.14976107776049186,-0.4017197370823883,1.0153693117770466,0.6590488057153554,0.3107354423149406,1.329137999738356,-0.8181714233751796,-0.6312704485557797,0.1951211504020895,0.16588167285776514,3.081835643844188,0.8725187348501537,0.48029056583855095,-0.05791371087003406,0.18051850104213735,0.4242723854370574,1.2551491998763629,1.329137999738356,-0.30599468976821914,2.149710642995687 | 3,220 |
Transporter | 89 | 201 | 2.442721 | 0.014577 | Q00765,Q70HW3,Q9HC21,P17900,P00846,P24390,Q15012,O00400,O00560,O14975,Q9Y6C9,Q9Y584,O43731,Q9BQE5,Q9H2V7,P30825,Q96H78,P51572,P49755,O75027,Q9HD45,Q9P2W9,Q15070,Q8N1F7,Q9UBX3,Q9H2D1,Q6NUK1,P33897,O75947,Q12769,Q8TB61,Q15363,Q9Y619,P13473,P50542,P05141,O60499,Q00325,Q9H6H4,O95249,Q6NUK4,P20020,O43808,Q9HC07,Q99805,Q9BQT8,P08195,P16260,Q12907,O95202,Q9H270,P54105,Q9BVK6,P12235,P08183,Q96ES6,Q9NZZ3,Q8IXU6,Q03518,O43760,O43752,Q93050,Q9Y6M7,Q9Y487,Q9Y3B3,P16615,Q9BSK2,Q9NZJ7,Q99523,Q8NFH4,P98194,P21281,Q9BRK0,Q92544,O14653,Q9Y5J6,Q9UI14,P05023,P11279,O96008,P24539,Q9H2J7,O43772,P53985,P56385,P12236,Q96NB2,Q8N2H4,P11166 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 521,11,533,527,25,27,38,41,541,542,566,49,52,53,70,71,73,584,595,81,83,85,91,609,103,107,625,633,630,652,137,141,142,647,649,664,158,676,692,175,686,697,696,197,198,203,719,217,731,727,753,232,752,235,239,242,254,262,264,269,290,305,315,319,327,342,348,359,369,371,382,381,399,398,393,413,431,424,425,423,455,457,458,473,482,480,486,492,497 | 2269,2236,2076,41,1711,541,1484,1014,2809,393,542,1763,52,290,269,458,696,158,1431,3108,1550,1240,2810,81,2632,1154,630,1490,727,175,1576,1744,3109,929,1804,423,25,424,987,664,1269,239,719,1435,497,425,235,480,647,217,342,527,697,381,3145,27,455,2437,988,1716,71,633,1216,882,2773,1552,2244,2472,1034,595,649,584,826,909,2683,836,2588,2866,1280,473,2247,232,1113,2638,922,1246,482,1657,990,1114,1303,2777,2721,2473,382,676,2740,521,1093,264,1440,896,1307,1442,652,913,731,1532,2570,1919,1851,2065,38,91,2414,141,746,1922,2383,2545,625,686,1507,1472,11,1225,1473,262,609,492,3153,371,2451,137,1099,815,1790,2939,3032,398,1024,305,2421,1415,242,73,486,2483,795,369,1895,198,53,203,2364,399,348,752,2456,753,107,1736,457,70,3103,692,1027,1179,197,533,83,3194,1367,2041,359,254,1082,2953,85,2172,1423,103,2266,431,2669,845,2427,1106,983,2108,781,327,319,49,413,1429,2175,142,2430,566,315 | 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| 3,220 |
Disproportionate short stature | 13 | 28 | 2.435999 | 0.014851 | Q03164,Q15125,Q7RTS9,O75718,Q7LGA3,Q96HY6,P10644,Q9BV10,Q14739,Q9UBM7,Q15392,Q9UHX1,O15228 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 225,3,328,518,302,498,341,182,57,476,29,94,567 | 957,567,673,2962,518,341,614,2536,1404,2472,225,1037,57,1250,3,29,838,809,302,328,1667,816,2872,498,1070,182,476,94 | 0.25319391829959953,0.6996089005935843,0.5496315311633986,-1.011355668757608,0.7666533960815253,1.155226944031845,0.6318674029638589,-0.6145736537180316,-0.04273894393938979,-0.5813222600056109,1.5464329024539194,0.18051850104213735,2.696447157783284,0.04753206007602352,4.059475865189276,3.081835643844188,0.3819335469967939,0.4101906969059821,1.2799015060822838,1.1928708296276316,-0.180686953630024,0.4101906969059821,-0.8702128004514436,0.8065529251182306,0.16588167285776514,1.7916438703696143,0.8593782894230385,2.3859816234515763 | 3,220 |
Progressive neurologic deterioration | 8 | 22 | 2.435842 | 0.014857 | Q9Y287,P07602,Q10713,Q9NZJ7,P04062,P54802,Q9NPL8,Q5XKP0 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 129,67,195,359,140,240,308,117 | 1347,140,67,1681,2986,614,1007,632,1215,2718,240,1138,2443,195,1779,117,2546,374,2784,308,359,129 | -0.012501405263775458,2.0949263106223306,2.625151948477759,-0.1962091472678085,-1.0471974781596876,0.6318674029638589,0.20968982025645352,0.6045715368978304,0.06244972498315363,-0.7324683402938643,1.4867565983726359,0.10698851923772369,-0.5647669902106163,1.7224537296137836,-0.243015814924118,2.2040841082583706,-0.6145736537180316,1.0665646357789607,-0.7837372383934156,1.242739174664162,1.1173718443197118,2.149710642995687 | 3,220 |
mitochondria | 9 | 12 | 2.43529 | 0.01488 | Q96H55,Q9NR31,Q9Y277,Q9NVH1,Q15388,O94826,Q969Q5,P45880,P21796 | Localization | OpenCell Localization | opencell_localization | 514,495,299,659,746,740,313,58,28 | 740,1155,28,58,1986,746,792,313,514,495,659,299 | 0.46633196825224094,0.09217774053922007,3.0914668286417912,2.6863034556568013,-0.3377332475042113,0.46633196825224094,0.4242723854370574,1.2303064299473192,0.7799802251689579,0.819799068860265,0.5771599918037926,1.2922439923397309 | 3,220 |
Sphingolipid metabolism in senescence | 6 | 11 | 2.43212 | 0.015011 | P16278,P04062,Q16739,O15269,Q96G23,Q13510 | Processes and pathways | WikiPathways | msigdb_wp | 614,140,561,422,154,59 | 422,140,1006,614,1214,2315,1404,616,59,561,154 | 0.9637783554965194,2.0949263106223306,0.20968982025645352,0.6318674029638589,0.06244972498315363,-0.49900777230689414,-0.04273894393938979,0.6318674029638589,2.6863034556568013,0.7130729829609895,1.9840933186443066 | 3,220 |
Sterol metabolism | 11 | 28 | 2.42697 | 0.015225 | Q15125,Q16850,O15118,Q9H2C2,P04062,P35610,Q15800,O75845,P54646,Q14739,Q15392 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 3,133,135,238,140,396,61,470,373,57,29 | 135,3110,470,1031,1323,1157,140,894,2504,396,1275,373,1190,2192,3048,2253,2947,57,3,2543,29,2544,61,133,238,476,2555,1676 | 2.1168898459726213,-1.3805716198597155,0.8593782894230385,0.18051850104213735,0.0025618247362464894,0.09217774053922007,2.0949263106223306,0.325039233943853,-0.5979243699912032,1.0153693117770466,0.03257833492512616,1.0665646357789607,0.07733154678623776,-0.43397226707902753,-1.156115218044601,-0.4664008031269134,-0.9757397882754897,2.696447157783284,4.059475865189276,-0.6145736537180316,3.081835643844188,-0.6145736537180316,2.6761460554500984,2.1278466494928105,1.4987330608256157,0.8593782894230385,-0.6145736537180316,-0.180686953630024 | 3,220 |
Establishment of protein localization to mitochondrial membrane | 8 | 20 | 2.423627 | 0.015366 | P62072,Q8N8Q8,Q9NS69,Q9Y584,Q9Y512,Q9Y5J9,Q9Y5J6,Q15070 | Processes and pathways | GO Biological process | msigdb_gobp | 153,295,45,49,502,344,413,91 | 2076,582,740,1270,2793,2055,2185,153,1019,91,1038,295,841,45,797,1761,502,49,413,344 | -0.38565873026838904,0.6725969576878126,0.46633196825224094,0.03257833492512616,-0.8009285846731938,-0.36964083848210133,-0.43397226707902753,1.9840933186443066,0.1951211504020895,2.417618705824693,0.18051850104213735,1.3045641696350245,0.3819335469967939,2.8965139805223146,0.4242723854370574,-0.22737331928668936,0.8065529251182306,2.8370461170260968,1.0025089619631318,1.155226944031845 | 3,220 |
Intracellular protein transmembrane transport | 10 | 24 | 2.421222 | 0.015468 | Q9Y5Y5,O14925,O75298,O96008,P31751,Q99595,O95831,Q15629,O75381,O60830 | Processes and pathways | GO Biological process | msigdb_gobp | 227,97,448,423,276,84,55,24,372,26 | 97,821,26,448,372,740,55,423,3022,276,649,2020,2060,1303,746,24,1009,3007,1894,493,84,2294,671,227 | 2.354208142416853,0.39607780869964226,3.1202885925230546,0.9117840142979674,1.0665646357789607,0.46633196825224094,2.7166936523547114,0.9637783554965194,-1.1195734835314772,1.3658339237407737,0.5771599918037926,-0.3536657728297462,-0.36964083848210133,0.017588330277042968,0.46633196825224094,3.1966266482758665,0.20968982025645352,-1.0832688429088466,-0.2901881007744104,0.819799068860265,2.4595918230799607,-0.48268182979148255,0.5634104540353521,1.5464329024539194 | 3,220 |
Disproportionate short limb short stature | 10 | 23 | 2.421093 | 0.015474 | Q03164,Q15125,Q7RTS9,O75718,Q7LGA3,P10644,Q9BV10,Q14739,Q9UBM7,Q15392 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 225,3,328,518,302,341,182,57,476,29 | 957,567,2962,518,341,2536,1404,2472,225,1037,57,3,29,838,809,302,328,1667,816,2872,1070,182,476 | 0.25319391829959953,0.6996089005935843,-1.011355668757608,0.7666533960815253,1.155226944031845,-0.6145736537180316,-0.04273894393938979,-0.5813222600056109,1.5464329024539194,0.18051850104213735,2.696447157783284,4.059475865189276,3.081835643844188,0.3819335469967939,0.4101906969059821,1.2799015060822838,1.1928708296276316,-0.180686953630024,0.4101906969059821,-0.8702128004514436,0.16588167285776514,1.7916438703696143,0.8593782894230385 | 3,220 |
Cholesterol binding | 6 | 13 | 2.419802 | 0.015529 | O95772,Q14108,O15118,P35610,P45880,P21796 | Functions | GO Molecular function | msigdb_gomf | 128,101,135,396,58,28 | 135,3110,1323,128,2897,28,2081,394,396,58,1190,101,1045 | 2.1168898459726213,-1.3805716198597155,0.0025618247362464894,2.149710642995687,-0.9051717595444062,3.0914668286417912,-0.38565873026838904,1.0153693117770466,1.0153693117770466,2.6863034556568013,0.07733154678623776,2.3116287576952588,0.18051850104213735 | 3,220 |
Exopeptidase activity | 10 | 34 | 2.417332 | 0.015635 | Q9H3G5,Q969V3,O75844,P42785,Q9HB40,Q7Z2K6,P10619,P55786,Q9NZ08,O14773 | Functions | GO Molecular function | msigdb_gomf | 68,6,40,72,110,114,20,86,152,214 | 214,40,674,1005,322,20,3166,2945,2815,803,72,2122,1279,1090,86,1635,3117,3104,886,114,764,1203,6,2455,1732,1011,68,1177,110,1149,2992,2787,152,223 | 1.6173742844059265,2.9359031050233613,0.5496315311633986,0.20968982025645352,1.2053723631183846,3.2722229339827167,-1.9013859901122099,-0.9757397882754897,-0.8181714233751796,0.4101906969059821,2.553171637047871,-0.4017197370823883,0.03257833492512616,0.13650467332375438,2.449120847556878,-0.16520434781562565,-1.3996966052075874,-1.3425212153140684,0.33931075924719056,2.2257201697391493,0.4523428510935623,0.07733154678623776,3.9306040408924114,-0.5647669902106163,-0.21177118338905118,0.20968982025645352,2.6149113753676136,0.09217774053922007,2.2580543426491517,0.10698851923772369,-1.0471974781596876,-0.7837372383934156,1.9952538492017513,1.5583068029385927 | 3,220 |
Chloride transport | 9 | 13 | 2.411409 | 0.015891 | P51798,P54105,Q4KMQ2,Q9UHG3,P08183,Q9Y696,P30536,Q9C0H2,P51790 | Processes and pathways | GO Biological process | msigdb_gobp | 160,232,654,106,239,340,394,51,511 | 2578,239,394,511,160,232,922,654,872,51,694,106,340 | -0.6480150957535664,1.4867565983726359,1.0153693117770466,0.7799802251689579,1.9054783305621512,1.5226240055116986,0.2963992009112666,0.5771599918037926,0.3535502000193913,2.807136845978207,0.5358230652915174,2.2795311992853793,1.167798228149572 | 3,220 |
Active ion transmembrane transporter activity | 21 | 41 | 2.402942 | 0.016264 | P98194,P21281,P05141,P51798,Q00325,O00400,P05023,Q9Y6M7,P20020,Q9H2J7,Q7KZN9,Q9UDW1,P08195,P13073,P16615,O14548,Q9HD20,P12236,P12235,Q96ES6,P51790 | Functions | GO Molecular function | msigdb_gomf | 382,381,664,160,676,41,424,315,697,457,332,204,719,212,342,592,90,480,235,242,511 | 41,592,727,849,424,987,664,1269,719,1522,2146,235,480,212,342,697,824,381,3145,1057,1463,1552,2244,511,160,836,922,1114,382,676,1093,332,242,1736,457,1027,90,204,2266,1429,315 | 2.926074846462015,0.6590488057153554,0.48029056583855095,0.36775773642059567,0.9637783554965194,0.22422470806964243,0.5634104540353521,0.03257833492512616,0.49421881017368724,-0.10366479969187105,-0.417824150950574,1.4987330608256157,0.8462116178421202,1.6291279725959298,1.155226944031845,0.5219848971605708,0.39607780869964226,1.0410159526015372,-1.6346231136290568,0.16588167285776514,-0.07312611883137438,-0.11899154943441288,-0.4664008031269134,0.7799802251689579,1.9054783305621512,0.3819335469967939,0.2963992009112666,0.12176409384605623,1.0410159526015372,0.5496315311633986,0.13650467332375438,1.180346153859077,1.4867565983726359,-0.21177118338905118,0.8987214683111048,0.1951211504020895,2.4281343418587498,1.6759461511432516,-0.4664008031269134,-0.04273894393938979,1.2303064299473192 | 3,220 |
Cholesterol metabolism | 10 | 26 | 2.40126 | 0.016339 | Q15125,Q16850,O15118,Q9H2C2,P04062,P35610,Q15800,P54646,Q14739,Q15392 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 3,133,135,238,140,396,61,373,57,29 | 135,3110,1031,1323,1157,140,894,2504,396,1275,373,1190,2192,3048,2253,2947,57,3,2543,29,2544,61,133,238,476,2555 | 2.1168898459726213,-1.3805716198597155,0.18051850104213735,0.0025618247362464894,0.09217774053922007,2.0949263106223306,0.325039233943853,-0.5979243699912032,1.0153693117770466,0.03257833492512616,1.0665646357789607,0.07733154678623776,-0.43397226707902753,-1.156115218044601,-0.4664008031269134,-0.9757397882754897,2.696447157783284,4.059475865189276,-0.6145736537180316,3.081835643844188,-0.6145736537180316,2.6761460554500984,2.1278466494928105,1.4987330608256157,0.8593782894230385,-0.6145736537180316 | 3,220 |
Protein targeting to mitochondrion | 20 | 48 | 2.393192 | 0.016703 | Q99797,P30536,P62072,Q9Y5J6,O60830,Q9NS69,Q9Y371,O96008,Q9Y584,O95831,Q8N4H5,Q10713,O00165,P51572,O14737,Q99595,P55786,Q9Y5J9,O14925,Q9Y512 | Processes and pathways | GO Biological process | msigdb_gobp | 384,394,153,413,26,45,564,423,49,55,62,195,320,584,582,84,86,344,97,502 | 320,582,97,820,821,26,1457,740,1155,1107,1680,55,423,1270,3022,1875,394,2185,908,584,86,153,1948,195,746,3006,1009,1038,790,2827,62,2803,84,384,1000,753,610,2294,45,797,1966,1083,564,2942,502,49,413,344 | 1.2053723631183846,0.6725969576878126,2.354208142416853,0.39607780869964226,0.39607780869964226,3.1202885925230546,-0.07312611883137438,0.46633196825224094,0.09217774053922007,0.12176409384605623,-0.1962091472678085,2.7166936523547114,0.9637783554965194,0.03257833492512616,-1.1195734835314772,-0.2901881007744104,1.0153693117770466,-0.43397226707902753,0.3107354423149406,0.6725969576878126,2.449120847556878,1.9840933186443066,-0.32184297973986525,1.7224537296137836,0.46633196825224094,-1.0832688429088466,0.20968982025645352,0.18051850104213735,0.4242723854370574,-0.8181714233751796,2.665974910710302,-0.8009285846731938,2.4595918230799607,1.0410159526015372,0.22422470806964243,0.46633196825224094,0.6454723370713444,-0.48268182979148255,2.8965139805223146,0.4242723854370574,-0.32184297973986525,0.15121046465169286,0.7130729829609895,-0.9580154630503087,0.8065529251182306,2.8370461170260968,1.0025089619631318,1.155226944031845 | 3,220 |
Anion channel activity | 9 | 12 | 2.385331 | 0.017064 | P51798,Q4KMQ2,Q9NW15,Q9Y277,Q9Y696,Q9C0H2,P45880,P21796,P51790 | Functions | GO Molecular function | msigdb_gomf | 160,654,694,299,340,51,58,28,511 | 2578,729,28,58,511,160,654,872,51,694,299,340 | -0.6480150957535664,0.48029056583855095,3.0914668286417912,2.6863034556568013,0.7799802251689579,1.9054783305621512,0.5771599918037926,0.3535502000193913,2.807136845978207,0.5358230652915174,1.2922439923397309,1.167798228149572 | 3,220 |
Gated channel activity | 11 | 14 | 2.384744 | 0.017091 | P51798,Q96ER9,Q4KMQ2,Q9NW15,Q9Y277,P21796,Q9Y696,Q9C0H2,P45880,Q9BVC6,P51790 | Functions | GO Molecular function | msigdb_gomf | 160,581,654,694,299,28,340,51,58,640,511 | 2578,2897,729,28,58,511,160,654,581,640,51,694,299,340 | -0.6480150957535664,-0.9051717595444062,0.48029056583855095,3.0914668286417912,2.6863034556568013,0.7799802251689579,1.9054783305621512,0.5771599918037926,0.6861169405393601,0.5908803010183907,2.807136845978207,0.5358230652915174,1.2922439923397309,1.167798228149572 | 3,220 |
Sterol biosynthesis | 7 | 17 | 2.383327 | 0.017157 | Q15125,Q16850,Q15392,O75845,P54646,Q14739,Q15800 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 3,133,29,470,373,57,61 | 470,1157,894,1275,373,3048,2253,2947,57,3,2543,29,2544,61,133,476,1676 | 0.8593782894230385,0.09217774053922007,0.325039233943853,0.03257833492512616,1.0665646357789607,-1.156115218044601,-0.4664008031269134,-0.9757397882754897,2.696447157783284,4.059475865189276,-0.6145736537180316,3.081835643844188,-0.6145736537180316,2.6761460554500984,2.1278466494928105,0.8593782894230385,-0.180686953630024 | 3,220 |
Organelle membrane contact site | 12 | 17 | 2.383112 | 0.017167 | Q96N66,O95772,Q96S66,Q96TC7,P51572,Q9NTJ5,A0FGR8,Q15388,O96008,Q9Y320,Q5XKP0,P27824 | Localization | GO Cellular component | msigdb_gocc | 192,128,872,967,584,693,769,746,423,563,117,471 | 769,1348,1152,128,423,471,584,1657,746,117,979,192,872,967,1960,693,563 | 0.4383230465774212,-0.012501405263775458,0.09217774053922007,2.149710642995687,0.9637783554965194,0.8593782894230385,0.6725969576878126,-0.180686953630024,0.46633196825224094,2.2040841082583706,0.23872600947530984,1.7340326951249647,0.3535502000193913,0.25319391829959953,-0.32184297973986525,0.5358230652915174,0.7130729829609895 | 3,220 |
Proton transmembrane transporter activity | 18 | 37 | 2.37429 | 0.017583 | Q13423,P21281,P24539,O00400,P51790,Q7KZN9,Q9UDW1,P12235,Q93050,O75964,Q96ES6,P13073,O14548,P00846,O75947,P05141,P56385,Q9Y487 | Functions | GO Molecular function | msigdb_gomf | 161,381,455,41,511,332,204,235,305,47,242,212,592,25,630,664,482,319 | 41,592,630,47,727,849,25,664,1269,1522,2146,235,212,824,381,3145,455,2437,1057,882,1463,1552,2996,511,1246,482,1114,676,161,332,305,242,1027,204,2266,319,1429 | 2.926074846462015,0.6590488057153554,0.6045715368978304,2.8370461170260968,0.48029056583855095,0.36775773642059567,3.1776123860617123,0.5634104540353521,0.03257833492512616,-0.10366479969187105,-0.417824150950574,1.4987330608256157,1.6291279725959298,0.39607780869964226,1.0410159526015372,-1.6346231136290568,0.8987214683111048,-0.5647669902106163,0.16588167285776514,0.33931075924719056,-0.07312611883137438,-0.11899154943441288,-1.0652042358274294,0.7799802251689579,0.04753206007602352,0.8462116178421202,0.12176409384605623,0.5496315311633986,1.9054783305621512,1.180346153859077,1.2551491998763629,1.4867565983726359,0.1951211504020895,1.6759461511432516,-0.4664008031269134,1.2178508611985153,-0.04273894393938979 | 3,220 |
Polyneuropathy | 7 | 21 | 2.373107 | 0.017639 | P07602,P03886,Q9NZJ7,P04066,O95831,P00846,Q15041 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 67,7,359,300,55,25,505 | 798,1031,1804,55,25,7,300,67,2053,1057,633,2058,2958,1018,505,1987,1640,2164,533,359,2231 | 0.4101906969059821,0.18051850104213735,-0.2586989329734473,2.7166936523547114,3.1776123860617123,3.869760435421595,1.2799015060822838,2.625151948477759,-0.36964083848210133,0.16588167285776514,0.6045715368978304,-0.36964083848210133,-0.9935197104671422,0.1951211504020895,0.7932800225164705,-0.3377332475042113,-0.16520434781562565,-0.417824150950574,0.7532993971393909,1.1173718443197118,-0.4501643839012559 | 3,220 |
Endoplasmic reticulum membrane organization | 6 | 9 | 2.370226 | 0.017777 | Q8NHH9,Q15363,Q9NQC3,Q9P2W9,Q6P1A2,Q15041 | Processes and pathways | GO Biological process | msigdb_gobp | 237,141,306,85,410,505 | 1576,521,2381,505,141,410,237,306,85 | -0.13435689396020284,0.7666533960815253,-0.5317956557309711,0.7932800225164705,2.0949263106223306,1.0025089619631318,1.4987330608256157,1.2551491998763629,2.4595918230799607 | 3,220 |
Electron transport chain oxphos system in mitochondria | 24 | 56 | 2.361151 | 0.018218 | O43676,P03886,O14949,P00846,P05141,O75306,O95139,O75964,P14406,Q99643,P24539,Q7KZN9,Q9UDW1,P13073,O14548,Q9Y6M9,Q9Y6N1,P56385,O75251,P12236,P12235,P22695,P21912,O75947 | Processes and pathways | WikiPathways | msigdb_wp | 1,7,22,25,664,283,544,47,188,318,455,332,204,212,592,345,346,482,600,480,235,245,632,630 | 1710,592,1484,22,1548,1,2673,600,283,1907,1908,859,630,47,544,663,2374,1133,1398,2532,849,25,7,664,1269,800,2146,235,480,212,188,2754,1085,2216,824,632,245,455,2437,3195,1215,1057,882,2996,2855,1328,1246,482,2448,1614,332,318,204,1083,345,346 | -0.21177118338905118,0.6590488057153554,-0.08837640269605082,3.2155945533343884,-0.11899154943441288,4.194747446409669,-0.7154791723941134,0.6454723370713444,1.329137999738356,-0.30599468976821914,-0.30599468976821914,0.3535502000193913,0.6045715368978304,2.8370461170260968,0.7265093315527947,0.5634104540353521,-0.5317956557309711,0.10698851923772369,-0.04273894393938979,-0.6145736537180316,0.36775773642059567,3.1776123860617123,3.869760435421595,0.5634104540353521,0.03257833492512616,0.4101906969059821,-0.417824150950574,1.4987330608256157,0.8462116178421202,1.6291279725959298,1.745592646919517,-0.7665970008859604,0.13650467332375438,-0.4501643839012559,0.39607780869964226,0.6045715368978304,1.4747593560996295,0.8987214683111048,-0.5647669902106163,-2.5516940759544804,0.06244972498315363,0.16588167285776514,0.33931075924719056,-1.0652042358274294,-0.8528131358802458,0.0025618247362464894,0.04753206007602352,0.8462116178421202,-0.5647669902106163,-0.14976107776049186,1.180346153859077,1.2178508611985153,1.6759461511432516,0.15121046465169286,1.155226944031845,1.155226944031845 | 3,220 |
Dyspnea | 26 | 97 | 2.356956 | 0.018425 | P35637,P21281,P03886,P04062,Q9Y619,P53701,P00846,P06280,O75306,O75844,P23786,Q92804,O75419,P49748,Q15165,O95831,Q13510,Q96EY8,P07602,P10644,Q9UHX1,Q9NZJ7,P10253,P12235,Q7LG56,Q16134 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 260,381,7,140,142,280,25,284,283,40,168,296,303,433,440,55,59,452,67,341,94,359,362,235,374,250 | 1151,2305,2732,1349,283,303,848,40,1576,1350,55,1157,25,1432,7,140,772,284,2533,67,1765,2308,2881,971,362,341,2932,3101,235,2564,1272,3203,2610,381,2312,2715,168,2346,260,1353,2957,2821,825,850,2348,3133,433,1035,1747,2218,472,1328,836,1379,2866,280,2443,2444,2060,1060,676,1530,1065,2412,59,1356,1095,3123,2722,2287,2515,440,250,2383,1169,374,1698,296,2968,2888,634,1231,1259,2421,452,2227,2169,2228,1733,2487,2623,613,359,672,94,2893,142 | 0.09217774053922007,-0.49900777230689414,-0.7495074930568375,-0.012501405263775458,1.329137999738356,1.2675366093469385,0.36775773642059567,2.9359031050233613,-0.13435689396020284,-0.012501405263775458,2.7166936523547114,0.09217774053922007,3.1776123860617123,-0.05791371087003406,3.869760435421595,2.0949263106223306,0.4383230465774212,1.329137999738356,-0.6145736537180316,2.625151948477759,-0.243015814924118,-0.49900777230689414,-0.8876655391405662,0.23872600947530984,1.104706025521293,1.155226944031845,-0.9580154630503087,-1.304733070955934,1.4987330608256157,-0.6312704485557797,0.03257833492512616,-3.003507729328924,-0.6648079405015793,1.0410159526015372,-0.49900777230689414,-0.7324683402938643,1.8373970276820892,-0.5153789425131554,1.4144582543439532,-0.012501405263775458,-0.9935197104671422,-0.8181714233751796,0.39607780869964226,0.36775773642059567,-0.5153789425131554,-1.5158810860908465,0.9508178956967717,0.18051850104213735,-0.22737331928668936,-0.4501643839012559,0.8593782894230385,0.0025618247362464894,0.3819335469967939,-0.027601585489929144,-0.8702128004514436,1.3536237939644702,-0.5647669902106163,-0.5647669902106163,-0.36964083848210133,0.16588167285776514,0.5496315311633986,-0.10366479969187105,0.16588167285776514,-0.5482582308154097,2.6863034556568013,-0.012501405263775458,0.13650467332375438,-1.4381490842074915,-0.7324683402938643,-0.48268182979148255,-0.5979243699912032,0.937832102041449,1.4507021690856339,-0.5317956557309711,0.09217774053922007,1.0665646357789607,-0.1962091472678085,1.3045641696350245,-1.011355668757608,-0.8876655391405662,0.6045715368978304,0.06244972498315363,0.04753206007602352,-0.5482582308154097,0.9117840142979674,-0.4501643839012559,-0.417824150950574,-0.4501643839012559,-0.21177118338905118,-0.5813222600056109,-0.6648079405015793,0.6454723370713444,1.1173718443197118,0.5634104540353521,2.3859816234515763,-0.8876655391405662,2.0949263106223306 | 3,220 |
protein modifying enzyme | 10 | 24 | 2.356219 | 0.018462 | O60725,Q6P2P2,Q92791,O75718,Q86YN1,P51812,Q12797,Q9UMR5,Q15418,P50897 | Functions | Panther Protein class | panther_protein_class | 100,491,429,518,79,461,559,56,253,31 | 1265,2048,1626,959,1975,100,518,577,31,461,2883,1817,559,1887,253,491,669,79,1389,429,1861,1830,56,2983 | 0.03257833492512616,-0.36964083848210133,-0.16520434781562565,0.25319391829959953,-0.3377332475042113,2.3329493132091454,0.7666533960815253,0.6861169405393601,3.072192431575852,0.8856330846497343,-0.8876655391405662,-0.2586989329734473,0.7130729829609895,-0.2901881007744104,1.4386420412496126,0.819799068860265,0.5634104540353521,2.5013284307582575,-0.027601585489929144,0.9637783554965194,-0.27442293885448277,-0.2586989329734473,2.7065772080315718,-1.029248107858703 | 3,220 |
Antiporter activity | 8 | 11 | 2.355864 | 0.01848 | P51798,P12236,Q9UBX3,P12235,P08195,P16260,P05141,P51790 | Functions | GO Molecular function | msigdb_gomf | 160,480,103,235,719,217,664,511 | 727,664,719,235,480,217,2244,511,160,1093,103 | 0.48029056583855095,0.5634104540353521,0.49421881017368724,1.4987330608256157,0.8462116178421202,1.5819939425106004,-0.4664008031269134,0.7799802251689579,1.9054783305621512,0.13650467332375438,2.300945191798539 | 3,220 |
Mitophagy | 8 | 11 | 2.355015 | 0.018522 | Q96HS1,Q15388,Q9NS69,O96008,O94826,Q8IWA4,P21796,Q8N4H5 | Processes and pathways | Reactome Pathways | msigdb_reactome | 779,746,45,423,740,792,28,62 | 740,1155,423,1875,28,804,746,792,62,779,45 | 0.46633196825224094,0.09217774053922007,0.9637783554965194,-0.2901881007744104,3.0914668286417912,0.4101906969059821,0.46633196825224094,0.4242723854370574,2.665974910710302,0.4383230465774212,2.8965139805223146 | 3,220 |
Lipid localization | 29 | 75 | 2.350464 | 0.01875 | O15118,P04062,O95674,P35610,O15260,P30536,P31751,P17900,Q9Y679,Q6P1A2,P23786,O14975,Q9NP80,P09455,Q9BQE5,Q8WTV0,Q99720,P07602,Q9H2V7,Q14534,O43772,Q9UJZ1,Q9BUR5,Q14108,Q9NZJ7,Q9H2C2,P08183,P11166,P35790 | Processes and pathways | GO Biological process | msigdb_gobp | 135,140,271,396,268,394,276,527,278,410,168,542,174,180,53,54,63,67,70,462,458,477,222,101,359,238,239,497,248 | 769,3214,542,135,268,458,696,3108,2078,1744,1628,271,784,2921,140,3004,2956,67,1681,1872,239,180,497,833,527,1213,2081,168,988,394,276,1088,633,396,248,1034,666,1190,2192,3199,1441,101,462,561,654,1692,410,1507,2916,1473,3149,54,1259,3033,1860,63,53,1540,222,1734,1045,1449,238,70,2230,174,359,1082,2555,3196,477,2671,1546,278,704 | 0.4383230465774212,-4.064670371317343,0.7265093315527947,2.1168898459726213,1.3780223384827002,0.8856330846497343,0.5219848971605708,-1.3615133499639909,-0.38565873026838904,-0.22737331928668936,-0.16520434781562565,1.3780223384827002,0.4242723854370574,-0.9403463011428995,2.0949263106223306,-1.0832688429088466,-0.9935197104671422,2.625151948477759,-0.1962091472678085,-0.2901881007744104,1.4867565983726359,1.7916438703696143,0.8065529251182306,0.3819335469967939,0.7532993971393909,0.06244972498315363,-0.38565873026838904,1.8373970276820892,0.22422470806964243,1.0153693117770466,1.3658339237407737,0.13650467332375438,0.6045715368978304,1.0153693117770466,1.4627412434131177,0.18051850104213735,0.5634104540353521,0.07733154678623776,-0.43397226707902753,-2.899313850240335,-0.05791371087003406,2.3116287576952588,0.8856330846497343,0.7130729829609895,0.5771599918037926,-0.1962091472678085,1.0025089619631318,-0.08837640269605082,-0.9227318742944672,-0.07312611883137438,-1.654672157179074,2.7368859058038453,0.04753206007602352,-1.1195734835314772,-0.27442293885448277,2.665974910710302,2.7469618056075022,-0.10366479969187105,1.5583068029385927,-0.21177118338905118,0.18051850104213735,-0.05791371087003406,1.4987330608256157,2.604656773633113,-0.4501643839012559,1.8145574051151347,1.1173718443197118,0.15121046465169286,-0.6145736537180316,-2.5757075512735597,0.8593782894230385,-0.6985396234928575,-0.10366479969187105,1.3658339237407737,0.5219848971605708 | 3,220 |
Optic disc pallor | 14 | 54 | 2.347501 | 0.0189 | O75306,Q9Y287,O43676,P51798,Q10713,P03886,Q9Y6M9,Q9H061,Q9H6K4,Q86Y39,Q9NPL8,O95831,P00846,Q96CU9 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 283,129,1,160,195,7,345,9,10,172,308,55,25,155 | 1801,830,1239,1653,1,1802,798,600,283,1907,1457,1908,2634,1155,55,2532,25,7,728,2501,1840,2216,3195,2855,160,3037,2958,2253,195,1784,172,3138,680,1040,1390,1023,2844,155,2227,872,1733,1044,1000,9,1047,1318,10,308,613,1208,389,129,1428,345 | -0.2586989329734473,0.3819335469967939,0.04753206007602352,-0.180686953630024,4.194747446409669,-0.2586989329734473,0.4101906969059821,0.6454723370713444,1.329137999738356,-0.30599468976821914,-0.07312611883137438,-0.30599468976821914,-0.681649331993938,0.09217774053922007,2.7166936523547114,-0.6145736537180316,3.1776123860617123,3.869760435421595,0.48029056583855095,-0.5979243699912032,-0.27442293885448277,-0.4501643839012559,-2.5516940759544804,-0.8528131358802458,1.9054783305621512,-1.1378144715215195,-0.9935197104671422,-0.4664008031269134,1.7224537296137836,-0.243015814924118,1.8259864180767964,-1.5551706483297403,0.5496315311633986,0.18051850104213735,-0.027601585489929144,0.1951211504020895,-0.8354661427807923,1.9729153800776973,-0.4501643839012559,0.3535502000193913,-0.21177118338905118,0.18051850104213735,0.22422470806964243,3.817243530612087,0.18051850104213735,0.017588330277042968,3.8084575200102933,1.242739174664162,0.6454723370713444,0.07733154678623776,1.0410159526015372,2.149710642995687,-0.04273894393938979,1.155226944031845 | 3,220 |
Mitochondrial respiratory chain complex assembly | 17 | 43 | 2.343451 | 0.019106 | O75306,O43676,P03886,O95139,Q9Y2R0,Q9H061,Q8N8Q8,Q6DKK2,Q86Y39,Q15070,Q9P0S2,Q9BSK2,Q9Y512,O95831,Q9NX14,Q9Y6M9,Q96CU9 | Processes and pathways | GO Biological process | msigdb_gobp | 283,1,7,544,139,9,295,428,172,91,16,348,502,55,613,345,155 | 1484,1548,1,1151,2673,600,283,1908,859,544,663,2374,1398,55,2532,7,3195,1328,1723,91,2448,1614,1784,428,172,3138,295,1040,155,2698,1205,348,1733,9,1178,613,1208,797,16,1761,139,502,345 | -0.08837640269605082,-0.11899154943441288,4.194747446409669,0.09217774053922007,-0.7154791723941134,0.6454723370713444,1.329137999738356,-0.30599468976821914,0.3535502000193913,0.7265093315527947,0.5634104540353521,-0.5317956557309711,-0.04273894393938979,2.7166936523547114,-0.6145736537180316,3.869760435421595,-2.5516940759544804,0.0025618247362464894,-0.21177118338905118,2.417618705824693,-0.5647669902106163,-0.14976107776049186,-0.243015814924118,0.9637783554965194,1.8259864180767964,-1.5551706483297403,1.3045641696350245,0.18051850104213735,1.9729153800776973,-0.7154791723941134,0.07733154678623776,1.1426321922261868,-0.21177118338905118,3.817243530612087,0.09217774053922007,0.6454723370713444,0.07733154678623776,0.4242723854370574,3.476430925767484,-0.22737331928668936,2.1059164207950953,0.8065529251182306,1.155226944031845 | 3,220 |
Abnormal conjunctiva morphology | 7 | 24 | 2.339545 | 0.019307 | P28070,P04066,P10619,Q9NZ08,Q14739,Q13510,P06280 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 202,300,20,152,57,59,284 | 1678,1005,300,2434,284,20,1055,1745,2311,632,2736,202,3083,906,2120,2378,1307,59,57,2421,318,1028,694,152 | -0.1962091472678085,0.20968982025645352,1.2799015060822838,-0.5647669902106163,1.329137999738356,3.2722229339827167,0.16588167285776514,-0.22737331928668936,-0.49900777230689414,0.6045715368978304,-0.7495074930568375,1.6759461511432516,-1.2299257497204847,0.3107354423149406,-0.4017197370823883,-0.5317956557309711,0.017588330277042968,2.6863034556568013,2.696447157783284,-0.5482582308154097,1.2178508611985153,0.1951211504020895,0.5358230652915174,1.9952538492017513 | 3,220 |
Regulation of blood pressure | 9 | 20 | 2.339333 | 0.019318 | P09601,P42892,Q6RW13,P42785,P05023,Q9HB40,Q9NZ08,P20020,Q9UIQ6 | Processes and pathways | GO Biological process | msigdb_gobp | 576,130,524,72,424,110,152,697,223 | 718,2500,424,1941,576,1578,697,72,130,908,2409,1749,1777,886,524,1514,110,152,223,1073 | 0.49421881017368724,-0.5979243699912032,0.9637783554965194,-0.32184297973986525,0.6861169405393601,-0.13435689396020284,0.5219848971605708,2.553171637047871,2.138786894309507,0.3107354423149406,-0.5482582308154097,-0.22737331928668936,-0.243015814924118,0.33931075924719056,0.7666533960815253,-0.08837640269605082,2.2580543426491517,1.9952538492017513,1.5583068029385927,0.16588167285776514 | 3,220 |
Carbohydrate derivative transmembrane transporter activity | 8 | 10 | 2.33664 | 0.019458 | P12236,O00400,Q8TB61,P12235,Q6NUK1,L0R6Q1,P33897,P05141 | Functions | GO Molecular function | msigdb_gomf | 480,41,137,235,625,335,633,664 | 335,41,696,664,235,480,633,2244,625,137 | 1.167798228149572,2.926074846462015,0.5219848971605708,0.5634104540353521,1.4987330608256157,0.8462116178421202,0.6045715368978304,-0.4664008031269134,0.6182338533453158,2.1059164207950953 | 3,220 |
Steroid biosynthetic process | 17 | 47 | 2.335155 | 0.019535 | Q15125,P48449,Q16850,Q53GQ0,Q14534,P05023,Q9H2C2,Q9H3P7,P30536,Q15800,O75845,P54646,Q6P1A2,Q14739,Q13510,P16435,Q15392 | Processes and pathways | GO Biological process | msigdb_gobp | 3,261,133,164,462,424,238,400,394,61,470,373,410,57,59,347,29 | 619,542,3110,470,1031,1323,1157,424,1212,894,1493,347,1213,2081,2504,988,394,1275,2538,261,2123,373,3048,2253,59,2947,462,57,3,2543,29,2618,2254,2544,61,133,164,410,1199,1860,2784,856,238,400,476,1340,1676 | 0.6182338533453158,0.7265093315527947,-1.3805716198597155,0.8593782894230385,0.18051850104213735,0.0025618247362464894,0.09217774053922007,0.9637783554965194,0.06244972498315363,0.325039233943853,-0.08837640269605082,1.1426321922261868,0.06244972498315363,-0.38565873026838904,-0.5979243699912032,0.22422470806964243,1.0153693117770466,0.03257833492512616,-0.6145736537180316,1.4144582543439532,-0.4017197370823883,1.0665646357789607,-1.156115218044601,-0.4664008031269134,2.6863034556568013,-0.9757397882754897,0.8856330846497343,2.696447157783284,4.059475865189276,-0.6145736537180316,3.081835643844188,-0.6648079405015793,-0.4664008031269134,-0.6145736537180316,2.6761460554500984,2.1278466494928105,1.8828569071488772,1.0025089619631318,0.07733154678623776,-0.27442293885448277,-0.7837372383934156,0.36775773642059567,1.4987330608256157,1.0153693117770466,0.8593782894230385,0.0025618247362464894,-0.180686953630024 | 3,220 |
Protein insertion into membrane | 11 | 33 | 2.33311 | 0.019642 | Q8N4V1,Q9Y5J9,Q8N8Q8,Q9NPA0,Q9NS69,Q96A33,Q9Y584,P46379,Q15629,P62072,Q15070 | Processes and pathways | GO Biological process | msigdb_gobp | 33,344,295,267,45,272,49,111,24,153,91 | 582,1974,1347,726,740,1270,2055,2185,111,1303,153,1019,2856,91,24,1038,992,1471,3205,33,1641,295,841,272,267,45,1051,797,1761,502,49,413,344 | 0.6725969576878126,-0.3377332475042113,-0.012501405263775458,0.48029056583855095,0.46633196825224094,0.03257833492512616,-0.36964083848210133,-0.43397226707902753,2.236514157333144,0.017588330277042968,1.9840933186443066,0.1951211504020895,-0.8528131358802458,2.417618705824693,3.1966266482758665,0.18051850104213735,0.22422470806964243,-0.07312611883137438,-3.191689964213605,3.072192431575852,-0.16520434781562565,1.3045641696350245,0.3819335469967939,1.3780223384827002,1.3901891347163047,2.8965139805223146,0.18051850104213735,0.4242723854370574,-0.22737331928668936,0.8065529251182306,2.8370461170260968,1.0025089619631318,1.155226944031845 | 3,220 |
Transport of small molecules | 67 | 155 | 2.330879 | 0.01976 | P56589,Q99797,P98194,P21281,P48556,O15118,Q4KMQ2,Q8TB61,Q70HW3,P30519,P35610,Q8IYU8,P28074,P21796,P05141,P27105,P51798,Q8N4V1,Q9H4I9,P49721,O00400,Q9NW15,Q9Y277,P05023,P60900,Q93050,Q9C0H2,Q12797,Q8WTV0,Q9Y6B6,Q9Y6M7,P45880,P20020,Q9Y487,P09601,P35613,Q9UBV2,Q10713,Q15904,P30825,Q9H2J7,P28070,Q13546,O00231,O75027,P20618,Q13438,P28072,P10644,P16615,P53985,Q9HD20,Q9H300,Q9UJZ1,P61289,P12236,Q9UBX3,Q9BUN8,P12235,P08183,P11166,Q99436,P33897,Q9UEY8,Q9BU23,O43242,P51790 | Processes and pathways | Reactome Pathways | msigdb_reactome | 512,384,382,381,390,135,654,137,11,14,396,530,275,28,664,407,160,33,165,37,41,694,299,424,557,305,51,559,54,704,315,58,697,319,576,578,715,195,711,71,457,202,709,77,81,336,597,466,341,342,473,90,610,477,352,480,103,104,235,239,497,500,633,635,247,629,511 | 77,3060,41,1456,2929,135,629,81,1457,3110,2011,2852,1323,2791,727,1005,424,987,664,1054,1376,239,719,1435,576,341,497,235,480,1911,342,3125,2053,697,2502,336,381,3145,1086,28,2344,932,1524,2611,407,2314,202,466,275,988,14,1296,71,633,1436,396,2583,578,2760,895,1463,760,1552,1075,2019,58,390,1277,37,2084,511,160,1280,473,1113,922,2443,512,557,352,1114,1190,1140,1633,2411,2473,1162,382,2192,2740,2155,195,559,2088,597,709,949,1410,1727,1778,1922,711,654,1507,1310,11,3074,530,33,2924,1120,3153,137,54,841,1121,305,1101,1567,500,2391,1568,1043,384,1315,247,104,51,2456,1736,457,610,1514,165,1027,90,3194,3218,694,2876,715,103,635,1676,2266,477,829,2527,767,299,319,1428,1429,704,315 | 2.511726017793731,-1.1928979655043435,2.926074846462015,-0.07312611883137438,-0.9580154630503087,2.1168898459726213,0.6045715368978304,2.4804894818760905,-0.07312611883137438,-1.3805716198597155,-0.3536657728297462,-0.8528131358802458,0.0025618247362464894,-0.8009285846731938,0.48029056583855095,0.20968982025645352,0.9637783554965194,0.22422470806964243,0.5634104540353521,0.16588167285776514,-0.027601585489929144,1.4867565983726359,0.49421881017368724,-0.05791371087003406,0.6861169405393601,1.155226944031845,0.8065529251182306,1.4987330608256157,0.8462116178421202,-0.30599468976821914,1.155226944031845,-1.4574777798783827,-0.36964083848210133,0.5219848971605708,-0.5979243699912032,1.167798228149572,1.0410159526015372,-1.6346231136290568,0.13650467332375438,3.0914668286417912,-0.5153789425131554,0.2820303246081004,-0.10366479969187105,-0.6648079405015793,1.0025089619631318,-0.49900777230689414,1.6759461511432516,0.8725187348501537,1.3658339237407737,0.22422470806964243,3.5403143393794037,0.017588330277042968,2.553171637047871,0.6045715368978304,-0.05791371087003406,1.0153693117770466,-0.6480150957535664,0.6861169405393601,-0.7665970008859604,0.325039233943853,-0.07312611883137438,0.4523428510935623,-0.11899154943441288,0.15121046465169286,-0.3536657728297462,2.6863034556568013,1.0282049357246734,0.03257833492512616,2.994609178748287,-0.38565873026838904,0.7799802251689579,1.9054783305621512,0.03257833492512616,0.8593782894230385,0.12176409384605623,0.2963992009112666,-0.5647669902106163,0.7799802251689579,0.7130729829609895,1.1300138626320861,0.12176409384605623,0.07733154678623776,0.10698851923772369,-0.16520434781562565,-0.5482582308154097,-0.5813222600056109,0.09217774053922007,1.0410159526015372,-0.43397226707902753,-0.7495074930568375,-0.417824150950574,1.7224537296137836,0.7130729829609895,-0.38565873026838904,0.6590488057153554,0.5081168661324692,0.2676286265840488,-0.04273894393938979,-0.21177118338905118,-0.243015814924118,-0.30599468976821914,0.5081168661324692,0.5771599918037926,-0.08837640269605082,0.017588330277042968,3.6755062380906676,-1.2113809723326867,0.7532993971393909,3.072192431575852,-0.9403463011428995,0.12176409384605623,-1.7152768494821569,2.1059164207950953,2.7368859058038453,0.3819335469967939,0.12176409384605623,1.2551491998763629,0.13650467332375438,-0.11899154943441288,0.8065529251182306,-0.5317956557309711,-0.11899154943441288,0.18051850104213735,1.0410159526015372,0.017588330277042968,1.4747593560996295,2.2902460247357626,2.807136845978207,-0.5647669902106163,-0.21177118338905118,0.8987214683111048,0.6454723370713444,-0.08837640269605082,1.8828569071488772,0.1951211504020895,2.4281343418587498,-2.5040191268880743,-9.363713338751078,0.5358230652915174,-0.8702128004514436,0.5081168661324692,2.300945191798539,0.6045715368978304,-0.180686953630024,-0.4664008031269134,0.8593782894230385,0.39607780869964226,-0.5979243699912032,0.4523428510935623,1.2922439923397309,1.2178508611985153,-0.04273894393938979,-0.04273894393938979,0.5219848971605708,1.2303064299473192 | 3,220 |
Purine nucleotide transport | 8 | 10 | 2.328042 | 0.01991 | Q08722,P12236,O00400,Q8TB61,P12235,Q6NUK1,P33897,P05141 | Processes and pathways | GO Biological process | msigdb_gobp | 547,480,41,137,235,625,633,664 | 41,696,664,235,480,633,2244,547,625,137 | 2.926074846462015,0.5219848971605708,0.5634104540353521,1.4987330608256157,0.8462116178421202,0.6045715368978304,-0.4664008031269134,0.7265093315527947,0.6182338533453158,2.1059164207950953 | 3,220 |
Glycosphingolipid metabolic process | 6 | 9 | 2.326862 | 0.019973 | Q99805,P04062,Q16739,P17900,P06865,P06280 | Processes and pathways | GO Biological process | msigdb_gobp | 198,140,561,527,285,284 | 140,284,285,1681,614,527,1019,561,198 | 2.0949263106223306,1.329137999738356,1.329137999738356,-0.1962091472678085,0.6318674029638589,0.7532993971393909,0.1951211504020895,0.7130729829609895,1.7108556718152539 | 3,220 |
Mitochondrial calcium ion transmembrane transport | 6 | 11 | 2.324389 | 0.020105 | O95202,Q9H4I9,Q96AQ8,Q8IYU8,P21796,Q9UJZ1 | Processes and pathways | GO Biological process | msigdb_gobp | 727,165,392,530,28,477 | 1457,727,28,530,1120,841,392,1315,165,477,1428 | -0.07312611883137438,0.48029056583855095,3.0914668286417912,0.7532993971393909,0.12176409384605623,0.3819335469967939,1.0282049357246734,0.017588330277042968,1.8828569071488772,0.8593782894230385,-0.04273894393938979 | 3,220 |
Mib complex | 8 | 11 | 2.322922 | 0.020183 | Q6UXV4,Q9NVH1,Q13505,Q5XKP0,Q9Y512,Q5HYI7,O75431,Q9BUR5 | Localization | GO Cellular component | msigdb_gocc | 586,659,143,117,502,571,555,222 | 555,2537,143,684,571,117,586,222,659,1050,502 | 0.7130729829609895,-0.6145736537180316,2.0839194517291406,0.5358230652915174,0.6996089005935843,2.2040841082583706,0.6725969576878126,1.5583068029385927,0.5771599918037926,0.18051850104213735,0.8065529251182306 | 3,220 |
mitochondrial carrier protein | 7 | 8 | 2.321347 | 0.020268 | Q9NZJ7,Q9Y6C9,Q70HW3,Q6NUK1,Q9HC21,P16260,Q9BSK2 | Functions | Panther Protein class | panther_protein_class | 359,566,11,625,533,217,348 | 217,676,625,11,348,533,359,566 | 1.5819939425106004,0.5496315311633986,0.6182338533453158,3.6755062380906676,1.1426321922261868,0.7532993971393909,1.1173718443197118,0.7130729829609895 | 3,220 |
Endoplasmic reticulum organization | 26 | 51 | 2.316212 | 0.020547 | Q9BRK0,Q00765,Q9NPA0,P50542,Q15363,Q96A33,P57088,O95197,Q6P1A2,Q15629,Q8N4V1,Q5JRA6,Q8N5M9,Q9H6H4,Q9NQC3,Q6NUK4,Q9NVV0,O14657,Q9P2W9,Q12907,O43765,Q8NHH9,P61026,P46379,Q8NFQ8,Q15041 | Processes and pathways | GO Biological process | msigdb_gobp | 399,521,267,649,141,272,528,23,410,24,33,678,169,692,306,686,714,705,85,731,726,237,623,111,765,505 | 769,928,1801,705,968,1485,1974,1347,726,1490,23,1576,111,649,528,623,1303,521,731,2381,2856,505,976,141,24,992,678,1471,2800,686,410,3205,33,169,1641,765,237,272,399,1540,1450,2002,692,2004,267,306,714,1262,1051,1082,85 | 0.4383230465774212,0.2820303246081004,-0.2586989329734473,0.5081168661324692,0.23872600947530984,-0.08837640269605082,-0.3377332475042113,-0.012501405263775458,0.48029056583855095,-0.08837640269605082,3.2061163777469694,-0.13435689396020284,2.236514157333144,0.5771599918037926,0.7532993971393909,0.6182338533453158,0.017588330277042968,0.7666533960815253,0.48029056583855095,-0.5317956557309711,-0.8528131358802458,0.7932800225164705,0.23872600947530984,2.0949263106223306,3.1966266482758665,0.22422470806964243,0.5496315311633986,-0.07312611883137438,-0.8009285846731938,0.5358230652915174,1.0025089619631318,-3.191689964213605,3.072192431575852,1.8373970276820892,-0.16520434781562565,0.4523428510935623,1.4987330608256157,1.3780223384827002,1.0153693117770466,-0.10366479969187105,-0.05791371087003406,-0.3377332475042113,0.5358230652915174,-0.3377332475042113,1.3901891347163047,1.2551491998763629,0.5081168661324692,0.04753206007602352,0.18051850104213735,0.15121046465169286,2.4595918230799607 | 3,220 |
Organic anion transmembrane transporter activity | 17 | 31 | 2.316085 | 0.020554 | P12236,Q96NB2,P30825,Q9UBX3,O00400,Q8TB61,Q9H2D1,Q9BQT8,Q9Y619,P12235,Q9HC21,Q6NUK1,P11166,Q9Y6M7,P53985,P05141,O43808 | Functions | GO Molecular function | msigdb_gomf | 480,486,71,103,41,137,107,203,142,235,533,625,497,315,473,664,696 | 41,2705,696,1154,929,664,719,497,235,480,71,2244,836,473,1093,3185,1922,625,1507,137,486,203,107,1736,1027,1179,533,103,845,142,315 | 2.926074846462015,-0.7324683402938643,0.5219848971605708,0.09217774053922007,0.2820303246081004,0.5634104540353521,0.49421881017368724,0.8065529251182306,1.4987330608256157,0.8462116178421202,2.553171637047871,-0.4664008031269134,0.3819335469967939,0.8593782894230385,0.13650467332375438,-2.295018412666495,-0.30599468976821914,0.6182338533453158,-0.08837640269605082,2.1059164207950953,0.833018588532747,1.6759461511432516,2.2688006578891002,-0.21177118338905118,0.1951211504020895,0.09217774053922007,0.7532993971393909,2.300945191798539,0.3819335469967939,2.0949263106223306,1.2303064299473192 | 3,220 |
Abnormality of the mitochondrion | 23 | 99 | 2.31539 | 0.020592 | O43676,P35637,P03886,Q9Y2R0,Q70HW3,Q9P0S2,Q9BUB7,P00846,Q96CU9,O75306,P23786,Q86Y39,Q9Y584,P49748,Q99757,Q9NPL8,Q7KZN9,P13073,Q9Y6M9,Q9UBX3,P12235,Q7LG56,Q16134 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 1,260,7,139,11,16,411,25,155,283,168,172,49,433,435,308,332,212,345,103,235,374,250 | 2008,1801,1710,1,2993,458,600,283,1907,1908,848,859,1398,2532,849,25,7,1271,960,2580,1108,3101,235,212,2564,2216,824,632,2504,168,2795,3195,2466,1215,260,1682,2821,1111,2718,1913,2348,433,2855,649,2218,1328,3112,1379,2248,2443,2061,676,1065,1779,250,1614,852,1009,1753,513,3030,679,2546,11,332,374,2779,172,3138,1040,2452,1231,155,1416,2696,2169,2784,435,2228,1205,1733,411,1000,1175,2487,1178,308,613,1208,797,16,2941,103,139,2213,1428,49,2176,345 | -0.3536657728297462,-0.2586989329734473,-0.21177118338905118,4.194747446409669,-1.0652042358274294,0.8856330846497343,0.6454723370713444,1.329137999738356,-0.30599468976821914,-0.30599468976821914,0.36775773642059567,0.3535502000193913,-0.04273894393938979,-0.6145736537180316,0.36775773642059567,3.1776123860617123,3.869760435421595,0.03257833492512616,0.25319391829959953,-0.6480150957535664,0.12176409384605623,-1.304733070955934,1.4987330608256157,1.6291279725959298,-0.6312704485557797,-0.4501643839012559,0.39607780869964226,0.6045715368978304,-0.5979243699912032,1.8373970276820892,-0.8009285846731938,-2.5516940759544804,-0.5813222600056109,0.06244972498315363,1.4144582543439532,-0.1962091472678085,-0.8181714233751796,0.12176409384605623,-0.7324683402938643,-0.30599468976821914,-0.5153789425131554,0.9508178956967717,-0.8528131358802458,0.5771599918037926,-0.4501643839012559,0.0025618247362464894,-1.3805716198597155,-0.027601585489929144,-0.4664008031269134,-0.5647669902106163,-0.36964083848210133,0.5496315311633986,0.16588167285776514,-0.243015814924118,1.4507021690856339,-0.14976107776049186,0.36775773642059567,0.20968982025645352,-0.22737331928668936,0.7799802251689579,-1.1195734835314772,0.5496315311633986,-0.6145736537180316,3.6755062380906676,1.180346153859077,1.0665646357789607,-0.7837372383934156,1.8259864180767964,-1.5551706483297403,0.18051850104213735,-0.5647669902106163,0.06244972498315363,1.9729153800776973,-0.04273894393938979,-0.7154791723941134,-0.417824150950574,-0.7837372383934156,0.9508178956967717,-0.4501643839012559,0.07733154678623776,-0.21177118338905118,1.0025089619631318,0.22422470806964243,0.09217774053922007,-0.5813222600056109,0.09217774053922007,1.242739174664162,0.6454723370713444,0.07733154678623776,0.4242723854370574,3.476430925767484,-0.9580154630503087,2.300945191798539,2.1059164207950953,-0.43397226707902753,-0.04273894393938979,2.8370461170260968,-0.417824150950574,1.155226944031845 | 3,220 |
Organic anion transport | 21 | 47 | 2.306217 | 0.021099 | Q8TB61,Q9Y619,Q9HC21,O00400,Q9NP80,Q9Y6M7,P07602,P30825,Q9H2J7,Q9BQT8,P53985,O60831,P12236,Q96NB2,Q9NZJ7,Q9UBX3,Q9H2D1,P12235,P11166,Q15041,O75915 | Processes and pathways | GO Biological process | msigdb_gobp | 137,142,533,41,174,315,67,71,457,203,473,478,480,486,359,103,107,235,497,505,509 | 41,2705,696,478,1154,509,929,3004,664,2341,67,719,3012,497,235,480,833,988,71,2244,836,473,922,1093,547,3185,505,976,1922,625,1507,137,486,203,107,1736,457,1027,1179,533,174,359,103,1676,845,142,315 | 2.926074846462015,-0.7324683402938643,0.5219848971605708,0.8462116178421202,0.09217774053922007,0.7799802251689579,0.2820303246081004,-1.0832688429088466,0.5634104540353521,-0.5153789425131554,2.625151948477759,0.49421881017368724,-1.1013917674356455,0.8065529251182306,1.4987330608256157,0.8462116178421202,0.3819335469967939,0.22422470806964243,2.553171637047871,-0.4664008031269134,0.3819335469967939,0.8593782894230385,0.2963992009112666,0.13650467332375438,0.7265093315527947,-2.295018412666495,0.7932800225164705,0.23872600947530984,-0.30599468976821914,0.6182338533453158,-0.08837640269605082,2.1059164207950953,0.833018588532747,1.6759461511432516,2.2688006578891002,-0.21177118338905118,0.8987214683111048,0.1951211504020895,0.09217774053922007,0.7532993971393909,1.8145574051151347,1.1173718443197118,2.300945191798539,-0.180686953630024,0.3819335469967939,2.0949263106223306,1.2303064299473192 | 3,220 |
Lipoprotein metabolic process | 8 | 20 | 2.306127 | 0.021104 | Q9Y2B2,P04062,Q9H490,Q9BQE5,Q5HYI8,O43292,Q9NUJ1,P50897 | Processes and pathways | GO Biological process | msigdb_gobp | 454,140,385,53,186,219,157,31 | 219,1349,2633,2863,1656,140,2055,31,976,561,186,2164,713,2888,1930,53,2002,385,157,454 | 1.5583068029385927,-0.012501405263775458,-0.681649331993938,-0.8702128004514436,-0.180686953630024,2.0949263106223306,-0.36964083848210133,3.072192431575852,0.23872600947530984,0.7130729829609895,1.7571336630517709,-0.417824150950574,0.5081168661324692,-0.8876655391405662,-0.30599468976821914,2.7469618056075022,-0.3377332475042113,1.0410159526015372,1.9617199652931325,0.9117840142979674 | 3,220 |
Steroid metabolism | 11 | 29 | 2.3022 | 0.021324 | Q15125,Q16850,O15118,Q9H2C2,P04062,P35610,Q15800,O75845,P54646,Q14739,Q15392 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 3,133,135,238,140,396,61,470,373,57,29 | 135,3110,470,1031,1323,1157,140,894,2504,396,1275,373,1190,2192,3048,2253,2947,57,3,2543,29,2544,61,133,2784,238,476,2555,1676 | 2.1168898459726213,-1.3805716198597155,0.8593782894230385,0.18051850104213735,0.0025618247362464894,0.09217774053922007,2.0949263106223306,0.325039233943853,-0.5979243699912032,1.0153693117770466,0.03257833492512616,1.0665646357789607,0.07733154678623776,-0.43397226707902753,-1.156115218044601,-0.4664008031269134,-0.9757397882754897,2.696447157783284,4.059475865189276,-0.6145736537180316,3.081835643844188,-0.6145736537180316,2.6761460554500984,2.1278466494928105,-0.7837372383934156,1.4987330608256157,0.8593782894230385,-0.6145736537180316,-0.180686953630024 | 3,220 |
Receptor | 10 | 28 | 2.30189 | 0.021341 | P57105,Q14108,Q9BUN8,Q9Y639,Q13641,Q567V2,Q9UQB8,Q9NR77,Q8WTV0,A6NIH7 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 194,101,104,330,301,178,113,243,54,30 | 30,2833,2654,372,718,2791,2341,801,665,1188,194,301,101,1818,178,54,1202,2389,104,876,1233,243,540,2878,1798,113,3059,330 | 3.072192431575852,-0.8354661427807923,-0.6985396234928575,1.0665646357789607,0.49421881017368724,-0.8009285846731938,-0.5153789425131554,0.4101906969059821,0.5634104540353521,0.07733154678623776,1.7224537296137836,1.2799015060822838,2.3116287576952588,-0.2586989329734473,1.803109914230054,2.7368859058038453,0.07733154678623776,-0.5317956557309711,2.2902460247357626,0.3535502000193913,0.06244972498315363,1.4867565983726359,0.7399180890945217,-0.8702128004514436,-0.243015814924118,2.236514157333144,-1.174476216167904,1.1928708296276316 | 3,220 |
Dementia | 23 | 61 | 2.286403 | 0.022231 | Q9Y287,P05067,P35637,O15118,P03886,P04062,P27544,P17900,P00846,P06865,P22626,O96008,Q13510,O76024,Q9Y487,Q9NQZ5,P07602,Q6Y7W6,Q14108,Q9NZJ7,P33897,Q7LG56,P21912 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 129,636,260,135,7,140,519,527,25,285,414,423,59,316,319,64,67,608,101,359,633,374,632 | 1801,135,820,1347,798,316,423,849,25,7,140,1400,772,636,285,67,971,2580,527,1007,632,414,2795,519,1215,1033,633,260,1463,1552,2408,850,2409,1138,2443,1190,3154,3038,1141,1065,59,101,1095,1195,608,374,3075,1097,1697,1643,2483,1419,2169,3000,64,359,1370,672,129,2942,319 | -0.2586989329734473,2.1168898459726213,0.39607780869964226,-0.012501405263775458,0.4101906969059821,1.2178508611985153,0.9637783554965194,0.36775773642059567,3.1776123860617123,3.869760435421595,2.0949263106223306,-0.04273894393938979,0.4383230465774212,0.5908803010183907,1.329137999738356,2.625151948477759,0.23872600947530984,-0.6480150957535664,0.7532993971393909,0.20968982025645352,0.6045715368978304,0.9896237665665621,-0.8009285846731938,0.7666533960815253,0.06244972498315363,0.18051850104213735,0.6045715368978304,1.4144582543439532,-0.07312611883137438,-0.11899154943441288,-0.5482582308154097,0.36775773642059567,-0.5482582308154097,0.10698851923772369,-0.5647669902106163,0.07733154678623776,-1.7356333775706634,-1.1378144715215195,0.10698851923772369,0.16588167285776514,2.6863034556568013,2.3116287576952588,0.13650467332375438,0.07733154678623776,0.6454723370713444,1.0665646357789607,-1.2113809723326867,0.13650467332375438,-0.1962091472678085,-0.16520434781562565,-0.5813222600056109,-0.04273894393938979,-0.417824150950574,-1.0652042358274294,2.665974910710302,1.1173718443197118,-0.012501405263775458,0.5634104540353521,2.149710642995687,-0.9580154630503087,1.2178508611985153 | 3,220 |
Metalloprotease | 8 | 27 | 2.284989 | 0.022313 | O43847,P42892,P09960,O75844,Q7Z2K6,P55786,Q9NZ08,Q9UIQ6 | Functions | Protein Atlas Molecular function | protein_atlas_molecular_function | 282,130,322,40,114,86,152,223 | 1456,282,1457,40,674,2432,322,3166,1242,130,1406,86,790,886,114,888,1732,1567,384,1124,1177,1149,2992,2787,152,223,1428 | -0.07312611883137438,1.329137999738356,-0.07312611883137438,2.9359031050233613,0.5496315311633986,-0.5647669902106163,1.2053723631183846,-1.9013859901122099,0.04753206007602352,2.138786894309507,-0.04273894393938979,2.449120847556878,0.4242723854370574,0.33931075924719056,2.2257201697391493,0.33931075924719056,-0.21177118338905118,-0.11899154943441288,1.0410159526015372,0.12176409384605623,0.09217774053922007,0.10698851923772369,-1.0471974781596876,-0.7837372383934156,1.9952538492017513,1.5583068029385927,-0.04273894393938979 | 3,220 |
Abnormal circulating cholesterol concentration | 11 | 35 | 2.281401 | 0.022525 | Q15125,P07602,Q9NZJ7,Q8N511,Q15800,Q9BV10,Q9NVI7,O75845,Q14739,Q9UBM7,Q15392 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 3,67,359,42,61,182,412,470,57,476,29 | 969,555,470,1432,1324,67,2468,1275,760,2408,1632,481,2441,990,1190,2741,2124,991,2354,57,3,29,2544,61,711,42,2420,875,182,2264,412,359,476,845,704 | 0.23872600947530984,0.7130729829609895,0.8593782894230385,-0.05791371087003406,0.0025618247362464894,2.625151948477759,-0.5813222600056109,0.03257833492512616,0.4523428510935623,-0.5482582308154097,-0.16520434781562565,0.8462116178421202,-0.5647669902106163,0.22422470806964243,0.07733154678623776,-0.7495074930568375,-0.4017197370823883,0.22422470806964243,-0.5153789425131554,2.696447157783284,4.059475865189276,3.081835643844188,-0.6145736537180316,2.6761460554500984,0.5081168661324692,2.916233933501683,-0.5482582308154097,0.3535502000193913,1.7916438703696143,-0.4664008031269134,1.0025089619631318,1.1173718443197118,0.8593782894230385,0.3819335469967939,0.5219848971605708 | 3,220 |
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