term stringlengths 2 121 | overlap int64 6 281 | setsize int64 7 499 | score float64 1.96 10.6 | pval float64 0 0.05 | edge stringlengths 41 1.97k | type stringclasses 5 values | subtype stringclasses 24 values | subtype_key stringclasses 24 values | edge_idxs stringlengths 11 1.17k | ann_idxs stringlengths 19 2.31k | ann_vals stringlengths 124 9.94k | sig_size int64 2.2k 3.73k |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
MFS transporter superfamily [IPR036259] | 10 | 13 | 2.868203 | 0.004128 | Q7L0J3,O43826,Q14728,P41440,Q8N697,O00400,Q9H2V7,P53985,Q99808,Q6NT16 | Sequence | InterPro Superfamily | interpro_homologous_superfamily | 65,396,146,239,504,20,478,26,93,62 | 20,396,973,239,26,146,1913,62,65,504,557,93,478 | 3.5772458059331473,0.8600596556567248,0.23827674360495169,1.3345857255664315,3.3901366110400533,1.8146416422908467,-0.312334586919792,2.587091406573943,2.4962294121503965,0.7161283312130348,0.6426230676699337,2.145115533980319,0.7524899549765799 | 3,040 |
Establishment of protein localization to membrane | 13 | 88 | 2.855862 | 0.004292 | O60725,O15118,O00560,Q9HD20,Q9Y584,Q9NS69,P46379,P43307,P63244,Q9UHB9,P62072,Q15629,Q4J6C6 | Processes and pathways | GO Biological process | msigdb_gobp | 0,98,256,40,72,107,15,240,114,21,117,153,61 | 2141,1609,256,643,1029,98,2565,1112,862,1285,0,2504,1887,1251,886,2005,1589,2303,806,406,2738,2342,508,2739,2264,348,2182,240,15,2620,890,1086,1333,1625,2213,2379,2183,1088,1663,117,114,790,811,1006,371,1527,940,960,1228,461,153,941,1833,61,1871,678,1704,2280,1772,1269,1982,1171,2774,1143,1310,881,1537,1847,2323,1880,582,1428,40,1924,107,275,1210,21,710,839,2067,2534,1076,565,72,1212,3011,2403 | -0.4717666193892306,-0.1579495805967917,1.2693680383752384,0.5492309315430891,0.19802266801457014,2.089059189581746,-0.7826010790948131,0.13702781813267018,0.33752223620233285,0.03368205509537154,4.663254621455635,-0.7334476908882873,-0.312334586919792,0.0545236662877855,0.3178291459077337,-0.3800230309908234,-0.13628593823390364,-0.5889493789129632,0.39614435776678325,0.8422863325591908,-0.9844682279779907,-0.6127320061884703,0.6978505521998537,-0.9844682279779907,-0.5652838070018109,0.982794416200427,-0.49497664277843795,1.3345857255664315,3.8004218159619,-0.8322673872621336,0.3178291459077337,0.1574422653969169,0.012752580513801317,-0.1579495805967917,-0.5182986952552782,-0.6366330002875932,-0.49497664277843795,0.1574422653969169,-0.17970910315454527,1.975195006162953,1.9895584986314332,0.4155348788904062,0.39614435776678325,0.21819012730572218,0.9130162849921596,-0.09324252520289562,0.2782103405843624,0.25828324277369913,0.07527824008221333,0.7705748236465301,1.7700163914806484,0.2782103405843624,-0.26772543458963366,2.599952157387,-0.2899790727297725,0.5113897708571208,-0.2015654664810097,-0.5652838070018109,-0.22351964620585527,0.0545236662877855,-0.3573554842529024,0.11652951958878897,-1.0103191649269512,0.13702781813267018,0.03368205509537154,0.33752223620233285,-0.09324252520289562,-0.26772543458963366,-0.5889493789129632,-0.2899790727297725,0.624080740847125,-0.029373324329508732,3.0444444324111646,-0.312334586919792,2.0608146287550606,1.2199202319870586,0.09594659045201429,3.566403837715786,0.4923630858030608,0.3766791785599655,-0.4027967817372936,-0.7334476908882873,0.1777736295870345,0.6426230676699337,2.350387100739699,0.09594659045201429,-2.1850685691959733,-0.6366330002875932 | 3,040 |
Chemical homeostasis | 31 | 169 | 2.850297 | 0.004368 | P78417,P62942,P53985,P09601,P35610,Q9NP80,P42785,Q9HD20,Q8WTV0,Q9HC07,Q9HD47,Q9Y487,Q93050,P09455,Q7L0J3,Q5BJF2,P30519,P05067,Q9Y6C9,O75503,Q99808,P02786,O15118,Q8N511,Q96CP7,P63244,P04062,P50897,Q9P246,O15254,Q9H4I9 | Processes and pathways | GO Biological process | msigdb_gobp | 130,11,26,284,289,163,36,40,41,175,176,177,323,63,65,68,70,74,214,91,93,219,98,105,237,114,243,120,248,242,252 | 804,1609,2404,1109,2844,98,242,353,1587,2299,386,2036,91,2206,2070,1886,2790,2881,2471,2406,2072,1436,2759,219,243,2937,1117,1476,74,1741,1190,1289,2408,1518,2370,1556,63,284,2442,1218,806,2337,958,2373,2039,519,1743,2006,1688,1616,1744,1654,2443,570,2081,1786,2340,975,1402,626,70,2545,289,1059,1966,1378,36,1293,606,485,120,1333,1898,1258,469,2266,629,26,742,1564,1624,2962,2268,2448,1449,2383,11,825,114,130,790,811,2853,1409,2550,3016,1632,2891,1197,893,320,2552,1764,941,1833,1573,979,68,2934,2518,1231,65,594,372,2916,105,1169,419,2813,2607,1773,41,813,323,1143,1272,237,1173,1576,529,1311,1175,2888,93,832,2631,1946,2951,2611,2168,1721,252,1462,175,1578,1579,40,176,163,1506,2944,1244,563,248,2584,710,1509,2585,2290,1363,2863,177,2295,3001,712,1106,1467,214,1027 | 0.39614435776678325,-0.1579495805967917,-0.6606536956722414,0.13702781813267018,-1.1684895504192612,2.089059189581746,1.3183566065504058,0.965437543137018,-0.13628593823390364,-0.5889493789129632,0.8777721115317447,-0.4027967817372936,2.1590406610189636,-0.5182986952552782,-0.42567786323215334,-0.312334586919792,-1.062451521523199,-1.24963046884146,-0.7090596464820835,-0.6606536956722414,-0.42567786323215334,-0.05057146887282142,-1.0103191649269512,1.3829766872888838,1.3183566065504058,-1.5019546528638092,0.13702781813267018,-0.07186090588440568,2.2963894486711554,-0.22351964620585527,0.09594659045201429,0.03368205509537154,-0.6606536956722414,-0.09324252520289562,-0.6366330002875932,-0.11471723023422291,2.574201082420162,1.186695066202737,-0.6847954503580282,0.07527824008221333,0.39614435776678325,-0.6127320061884703,0.25828324277369913,-0.6366330002875932,-0.4027967817372936,0.6795074351426921,-0.22351964620585527,-0.3800230309908234,-0.2015654664810097,-0.1579495805967917,-0.22351964620585527,-0.17970910315454527,-0.6847954503580282,0.624080740847125,-0.42567786323215334,-0.2455726333366303,-0.6127320061884703,0.23827674360495169,-0.029373324329508732,0.5680465845888625,2.377189975700653,-0.75796101573055,1.170003381143128,0.1777736295870345,-0.3573554842529024,-0.008265595708049227,3.1152639138541405,0.03368205509537154,0.5867930584046154,0.7343412937617894,1.960793573015321,0.012752580513801317,-0.312334586919792,0.0545236662877855,0.7524899549765799,-0.5652838070018109,0.5680465845888625,3.3901366110400533,0.45409450442527205,-0.11471723023422291,-0.1579495805967917,-1.618710430813493,-0.5652838070018109,-0.6847954503580282,-0.05057146887282142,-0.6366330002875932,3.8626651909366387,0.3766791785599655,1.9895584986314332,1.9028038748611003,0.4155348788904062,0.39614435776678325,-1.1684895504192612,-0.029373324329508732,-0.75796101573055,-2.49788388362525,-0.1579495805967917,-1.2769953776362524,0.09594659045201429,0.3178291459077337,1.0516490831696563,-0.75796101573055,-0.22351964620585527,0.2782103405843624,-0.26772543458963366,-0.11471723023422291,0.23827674360495169,2.4171533162766576,-1.4732257420217356,-0.7334476908882873,0.07527824008221333,2.4962294121503965,0.6054709229335996,0.9130162849921596,-1.3881021776971274,2.0608146287550606,0.11652951958878897,0.8244516693582026,-1.088736557366239,-0.8073693656405042,-0.22351964620585527,3.032555550251405,0.39614435776678325,1.0516490831696563,0.13702781813267018,0.0545236662877855,1.3507652191046324,0.11652951958878897,-0.11471723023422291,0.6795074351426921,0.03368205509537154,0.11652951958878897,-1.24963046884146,2.145115533980319,0.3766791785599655,-0.8322673872621336,-0.334793033079157,-1.5599592297881615,-0.8073693656405042,-0.4717666193892306,-0.2015654664810097,1.3020775180976913,-0.05057146887282142,1.649178704645811,-0.11471723023422291,-0.11471723023422291,3.0444444324111646,1.649178704645811,1.7250193216134055,-0.07186090588440568,-1.5019546528638092,0.07527824008221333,0.6426230676699337,1.3183566065504058,-0.7826010790948131,0.4923630858030608,-0.07186090588440568,-0.7826010790948131,-0.5652838070018109,0.012752580513801317,-1.1684895504192612,1.649178704645811,-0.5652838070018109,-2.052859180393565,0.4923630858030608,0.1574422653969169,-0.05057146887282142,1.414993690331867,0.21819012730572218 | 3,040 |
Apc c mediated degradation of cell cycle proteins | 16 | 53 | 2.844212 | 0.004452 | P20618,O60566,Q92530,P28070,Q9UJX3,P61289,P49721,Q9UL46,P53350,P30260,P28072,P49720,P24941,P28074,P60900,Q99436 | Processes and pathways | Reactome Pathways | msigdb_reactome | 154,287,322,193,352,293,142,238,145,147,277,278,212,312,85,420 | 642,2564,1470,2807,432,998,2033,287,1188,1000,2305,2178,154,212,2445,2007,1082,1083,1823,193,277,312,147,2720,1897,1790,278,142,1444,145,1593,85,293,1335,1900,2346,744,776,1865,2191,2088,1340,1416,322,541,420,2103,1538,838,352,951,238,1583 | 0.5492309315430891,-0.7826010790948131,-0.07186090588440568,-1.088736557366239,0.7885964023248992,0.21819012730572218,-0.4027967817372936,1.170003381143128,0.09594659045201429,0.21819012730572218,-0.5889493789129632,-0.49497664277843795,1.7550590252104994,1.414993690331867,-0.6847954503580282,-0.3800230309908234,0.1574422653969169,0.1574422653969169,-0.26772543458963366,1.509903867033398,1.2033338913699734,1.0687216574483722,1.799807445284277,-0.9587584321347755,-0.312334586919792,-0.2455726333366303,1.2033338913699734,1.8294352882830525,-0.05057146887282142,1.8146416422908467,-0.13628593823390364,2.2006057669567936,1.153258456656166,0.012752580513801317,-0.312334586919792,-0.6127320061884703,0.45409450442527205,0.4348513834489541,-0.2899790727297725,-0.49497664277843795,-0.42567786323215334,0.012752580513801317,-0.029373324329508732,1.0516490831696563,0.661098451902834,0.8244516693582026,-0.42567786323215334,-0.09324252520289562,0.3766791785599655,0.982794416200427,0.2782103405843624,1.3507652191046324,-0.11471723023422291 | 3,040 |
Lipid binding | 32 | 138 | 2.826589 | 0.004705 | O60313,Q9UM22,O94788,O00560,Q13045,P21796,P45880,Q9NQZ5,Q8NCC3,O15173,Q14849,Q96E52,Q9Y4G8,P35610,A6NIH7,Q8WTV0,Q9BQE5,Q14108,Q86YQ8,P09455,P28070,Q9NZJ7,Q96SU4,Q92643,O15118,Q9H6U6,P07602,P04062,Q96L92,P50897,Q13277,O15254 | Functions | GO Molecular function | msigdb_gomf | 377,129,134,256,265,12,14,144,17,394,152,157,31,289,35,41,45,52,314,63,193,345,87,223,98,367,244,243,246,120,371,242 | 1816,35,995,693,1547,256,517,1213,1731,2788,98,394,242,1186,1549,842,999,377,2819,737,1078,821,2958,134,2301,1888,2911,644,243,467,1476,2441,244,1615,1518,1556,63,2848,2948,2075,1252,2791,438,1219,1122,2239,12,570,2150,1191,2445,193,1290,2570,1787,289,1523,407,14,2741,2009,909,120,2884,2989,2046,1697,2743,2344,1380,2448,849,2625,1006,2853,1759,265,371,1632,2315,2128,52,2193,152,2810,1264,893,2900,1909,796,314,1804,17,1457,2774,41,2099,223,2165,1349,756,157,2727,246,87,1144,2775,2104,2462,2463,45,2230,1946,596,1878,1781,1208,1880,967,367,144,2172,345,1464,839,2585,3038,2787,129,2066,1182,1607,2754,2894,31,783,994,3001 | -0.26772543458963366,3.1152639138541405,0.21819012730572218,0.4923630858030608,-0.11471723023422291,1.2693680383752384,0.6795074351426921,0.07527824008221333,-0.22351964620585527,-1.062451521523199,2.089059189581746,0.8600596556567248,1.3183566065504058,0.09594659045201429,-0.11471723023422291,0.35713869105956414,0.21819012730572218,0.8954241674177924,-1.1151699685618548,0.45409450442527205,0.1574422653969169,0.3766791785599655,-1.618710430813493,1.8735753952262877,-0.5889493789129632,-0.312334586919792,-1.3881021776971274,0.5492309315430891,1.3183566065504058,0.7524899549765799,-0.07186090588440568,-0.6847954503580282,1.3183566065504058,-0.1579495805967917,-0.09324252520289562,-0.11471723023422291,2.574201082420162,-1.1684895504192612,-1.5599592297881615,-0.42567786323215334,0.0545236662877855,-1.062451521523199,0.7885964023248992,0.07527824008221333,0.13702781813267018,-0.5417340014635557,3.8419900405287315,0.624080740847125,-0.4717666193892306,0.09594659045201429,-0.6847954503580282,1.509903867033398,0.03368205509537154,-0.7826010790948131,-0.2455726333366303,1.170003381143128,-0.09324252520289562,0.8422863325591908,3.810841292230224,-0.9844682279779907,-0.3800230309908234,0.29805874290970236,1.960793573015321,-1.24963046884146,-1.9244726661529046,-0.4027967817372936,-0.2015654664810097,-0.9844682279779907,-0.6127320061884703,-0.008265595708049227,-0.6847954503580282,0.35713869105956414,-0.8322673872621336,0.21819012730572218,-1.1684895504192612,-0.22351964620585527,1.2529369403504902,0.9130162849921596,-0.1579495805967917,-0.5889493789129632,-0.44866742092299217,2.7894153625147196,-0.49497664277843795,1.7700163914806484,-1.088736557366239,0.0545236662877855,0.3178291459077337,-1.3045227910643165,-0.312334586919792,0.4155348788904062,1.0687216574483722,-0.2455726333366303,3.748046944176162,-0.05057146887282142,-1.0103191649269512,3.032555550251405,-0.42567786323215334,1.3829766872888838,-0.4717666193892306,0.012752580513801317,0.45409450442527205,1.7550590252104994,-0.9587584321347755,1.3183566065504058,2.2006057669567936,0.13702781813267018,-1.0103191649269512,-0.42567786323215334,-0.6847954503580282,-0.6847954503580282,2.9606979194992413,-0.5182986952552782,-0.334793033079157,0.6054709229335996,-0.2899790727297725,-0.22351964620585527,0.09594659045201429,-0.2899790727297725,0.25828324277369913,0.9305489204651839,1.8294352882830525,-0.4717666193892306,1.000093579058044,-0.05057146887282142,0.3766791785599655,-0.7826010790948131,-5.295709297428729,-1.0363129992676252,1.9173593554347703,-0.4027967817372936,0.11652951958878897,-0.13628593823390364,-0.9844682279779907,-1.2769953776362524,3.208350910072947,0.4348513834489541,0.23827674360495169,-2.052859180393565 | 3,040 |
Switching of origins to a post replicative state | 15 | 55 | 2.823091 | 0.004756 | Q92530,P28070,Q9UJX3,P61289,Q9UBD5,P49721,Q9UL46,P30260,P28072,P49720,P24941,P28074,P60900,Q9Y619,P20618 | Processes and pathways | Reactome Pathways | msigdb_reactome | 322,193,352,293,400,142,238,147,277,278,212,312,85,125,154 | 642,2564,1470,2807,998,1188,2178,154,212,1618,2445,2007,1082,1083,1823,193,277,312,147,1522,1292,931,2720,1897,1790,278,142,740,1444,1593,85,293,1335,1900,2346,744,776,1865,2191,2088,490,1340,1416,322,541,420,2103,1538,400,838,352,951,238,1583,125 | 0.5492309315430891,-0.7826010790948131,-0.07186090588440568,-1.088736557366239,0.21819012730572218,0.09594659045201429,-0.49497664277843795,1.7550590252104994,1.414993690331867,-0.1579495805967917,-0.6847954503580282,-0.3800230309908234,0.1574422653969169,0.1574422653969169,-0.26772543458963366,1.509903867033398,1.2033338913699734,1.0687216574483722,1.799807445284277,-0.09324252520289562,0.03368205509537154,0.2782103405843624,-0.9587584321347755,-0.312334586919792,-0.2455726333366303,1.2033338913699734,1.8294352882830525,0.45409450442527205,-0.05057146887282142,-0.13628593823390364,2.2006057669567936,1.153258456656166,0.012752580513801317,-0.312334586919792,-0.6127320061884703,0.45409450442527205,0.4348513834489541,-0.2899790727297725,-0.49497664277843795,-0.42567786323215334,0.7343412937617894,0.012752580513801317,-0.029373324329508732,1.0516490831696563,0.661098451902834,0.8244516693582026,-0.42567786323215334,-0.09324252520289562,0.8600596556567248,0.3766791785599655,0.982794416200427,0.2782103405843624,1.3507652191046324,-0.11471723023422291,1.946353972838871 | 3,040 |
Abnormality of the cerebrospinal fluid | 36 | 134 | 2.819365 | 0.004812 | Q9NR77,P21964,P00846,Q15392,O60826,Q9P0J0,P53701,O43676,P16435,P23786,O96028,O60566,Q86WC4,P30153,P03886,O43505,Q9Y5P6,P08236,P00403,O75312,Q08AM6,Q96L58,Q96CU9,Q9NZJ7,Q93009,P40855,Q86Y39,Q15125,O75306,P35222,P07602,P04062,O43464,O96000,Q10713,Q7KZN9 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 2,387,6,7,386,275,521,283,285,32,161,287,168,299,54,185,317,192,436,435,460,327,75,345,474,348,355,491,108,483,244,243,369,118,250,381 | 2404,1586,1368,1322,369,185,283,1112,1587,843,287,386,957,108,435,1215,2703,1151,2881,1736,2688,118,161,436,6,54,243,1740,2037,244,1932,192,2409,846,973,1891,1893,285,974,2618,1617,2939,2239,387,32,1559,3019,1965,299,2341,2693,483,2619,2668,348,2795,1748,2765,1592,1968,2621,1379,2412,1899,521,1445,1624,1483,1595,2124,1596,1006,1973,1828,1262,1299,460,777,250,1629,2515,1062,1701,491,7,1869,1012,1836,1068,381,1418,168,355,1095,2916,1496,2877,2281,2555,919,2628,474,1271,1272,75,1602,327,2132,3000,1504,2282,670,858,2393,1208,1540,708,2713,2255,2,2027,1049,1430,2287,2430,345,2256,275,690,992,2755,549,317,2992 | -0.6606536956722414,-0.13628593823390364,-0.008265595708049227,0.012752580513801317,0.9130162849921596,1.5567327633064831,1.186695066202737,0.13702781813267018,-0.13628593823390364,0.35713869105956414,1.170003381143128,0.8777721115317447,0.25828324277369913,2.046637516393822,0.7885964023248992,0.07527824008221333,-0.9331880544660163,0.11652951958878897,-1.24963046884146,-0.22351964620585527,-0.907755404541169,1.960793573015321,1.7250193216134055,0.7885964023248992,4.290668707384786,2.739511278775411,1.3183566065504058,-0.22351964620585527,-0.4027967817372936,1.3183566065504058,-0.334793033079157,1.525559168791652,-0.6606536956722414,0.35713869105956414,0.23827674360495169,-0.312334586919792,-0.312334586919792,1.186695066202737,0.23827674360495169,-0.8322673872621336,-0.1579495805967917,-1.5019546528638092,-0.5417340014635557,0.8777721115317447,3.196797074340647,-0.11471723023422291,-2.5704306881405343,-0.3573554842529024,1.1196073499123598,-0.6127320061884703,-0.907755404541169,0.7343412937617894,-0.8322673872621336,-0.8824588236038856,0.982794416200427,-1.062451521523199,-0.22351964620585527,-1.0103191649269512,-0.13628593823390364,-0.3573554842529024,-0.8322673872621336,-0.008265595708049227,-0.6606536956722414,-0.312334586919792,0.6795074351426921,-0.05057146887282142,-0.1579495805967917,-0.07186090588440568,-0.13628593823390364,-0.44866742092299217,-0.13628593823390364,0.21819012730572218,-0.3573554842529024,-0.26772543458963366,0.0545236662877855,0.03368205509537154,0.7705748236465301,0.4348513834489541,1.3020775180976913,-0.1579495805967917,-0.7334476908882873,0.1777736295870345,-0.2015654664810097,0.7343412937617894,4.164468347330218,-0.2899790727297725,0.21819012730572218,-0.26772543458963366,0.1777736295870345,0.8954241674177924,-0.029373324329508732,1.6796433852720836,0.965437543137018,0.1574422653969169,-1.3881021776971274,-0.07186090588440568,-1.2224259209783335,-0.5652838070018109,-0.75796101573055,0.29805874290970236,-0.8322673872621336,0.7524899549765799,0.0545236662877855,0.0545236662877855,2.2963894486711554,-0.13628593823390364,1.0345204898018696,-0.44866742092299217,-2.052859180393565,-0.07186090588440568,-0.5652838070018109,0.5303455219239778,0.35713869105956414,-0.6366330002875932,0.09594659045201429,-0.09324252520289562,0.4923630858030608,-0.9331880544660163,-0.5417340014635557,4.599675697788404,-0.3800230309908234,0.19802266801457014,-0.029373324329508732,-0.5652838070018109,-0.6606536956722414,1.000093579058044,-0.5417340014635557,1.2199202319870586,0.5113897708571208,0.23827674360495169,-0.9844682279779907,0.661098451902834,1.0687216574483722,-1.9244726661529046 | 3,040 |
Phospholipid metabolism | 7 | 18 | 2.816575 | 0.004854 | Q9HBU6,Q9UG56,Q9NPH0,Q6P1A2,P35790,Q96N66,Q9NUQ2 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 34,164,19,151,92,224,255 | 517,2663,92,2765,151,300,1268,1773,1390,2052,224,1274,34,1579,19,2633,255,164 | 0.6795074351426921,-0.8824588236038856,2.145115533980319,-1.0103191649269512,1.7849324461832374,1.1196073499123598,0.0545236662877855,-0.22351964620585527,-0.008265595708049227,-0.4027967817372936,1.3829766872888838,0.0545236662877855,3.1503484036762917,-0.11471723023422291,3.5880677323456616,-0.8322673872621336,1.2857481125261092,1.7250193216134055 | 3,040 |
Mitochondrial envelope | 62 | 313 | 2.791146 | 0.005252 | Q9NZ45,O60313,P57105,P00846,O60830,P21796,P22695,P45880,Q9P0J0,Q9NQZ5,Q96E52,Q99595,Q9Y2R0,O43676,Q567V2,P09601,P23786,Q70HW3,Q9NP80,Q9UG56,Q9BSK2,O43772,Q9H2D1,Q9UJS0,P03886,O14949,Q13423,O00165,P22830,Q9Y584,Q69YU5,Q96CU9,Q9Y277,P23396,Q9NZJ7,O43169,Q9Y6C9,P52888,Q9NR28,Q9H061,Q8WY22,Q7Z7F7,Q9BYT8,Q96AY3,Q86Y39,O75964,Q9UDW1,Q9NS69,P82933,Q9H4I9,O75306,O43464,Q9H3K2,P62072,Q8IYU8,P14406,O96000,Q13505,Q10713,Q7KZN9,Q9Y619,Q9NUQ2 | Localization | GO Cellular component | msigdb_gocc | 128,377,132,6,10,12,268,14,275,144,157,27,159,283,30,284,32,33,163,164,171,44,46,307,54,308,60,191,196,72,73,75,206,209,345,83,214,338,89,225,351,95,360,359,355,378,234,107,235,252,108,369,375,117,372,370,118,122,250,381,125,255 | 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| 3,040 |
Cdt1 association with the cdc6 orc origin complex | 12 | 38 | 2.785545 | 0.005344 | Q92530,P28070,P61289,Q9UBD5,P49721,Q9UL46,P28072,P49720,P60900,P28074,Q9Y619,P20618 | Processes and pathways | Reactome Pathways | msigdb_reactome | 322,193,293,400,142,238,277,278,85,312,125,154 | 642,2564,1470,2807,998,1188,2178,154,2445,2007,1082,1083,1823,193,277,312,2720,1897,1790,278,142,1444,1593,85,293,1335,1900,2346,776,1865,1340,322,420,2103,400,238,1583,125 | 0.5492309315430891,-0.7826010790948131,-0.07186090588440568,-1.088736557366239,0.21819012730572218,0.09594659045201429,-0.49497664277843795,1.7550590252104994,-0.6847954503580282,-0.3800230309908234,0.1574422653969169,0.1574422653969169,-0.26772543458963366,1.509903867033398,1.2033338913699734,1.0687216574483722,-0.9587584321347755,-0.312334586919792,-0.2455726333366303,1.2033338913699734,1.8294352882830525,-0.05057146887282142,-0.13628593823390364,2.2006057669567936,1.153258456656166,0.012752580513801317,-0.312334586919792,-0.6127320061884703,0.4348513834489541,-0.2899790727297725,0.012752580513801317,1.0516490831696563,0.8244516693582026,-0.42567786323215334,0.8600596556567248,1.3507652191046324,-0.11471723023422291,1.946353972838871 | 3,040 |
Mitotic g1 phase and g1 s transition | 22 | 74 | 2.770064 | 0.005605 | P00374,Q9UBD5,P49721,P28072,P49720,P20618,Q99436,P61289,P30153,P28074,P31350,Q92530,P28070,Q13547,P30154,P24941,P60900,Q14566,Q9UL46,P35244,O75419,Q9Y619 | Processes and pathways | Reactome Pathways | msigdb_reactome | 5,400,142,277,278,154,420,293,299,312,186,322,193,441,202,212,85,490,238,484,498,125 | 642,2564,1470,2807,998,498,1188,5,1588,2865,1000,2736,1685,569,1686,2305,2263,2178,154,212,1618,2445,2007,1082,1083,2506,1823,193,277,312,299,202,186,508,1522,1292,931,484,2720,1897,1790,2377,717,278,142,740,1444,1593,85,293,1335,1900,2346,1005,744,791,776,1037,1865,2191,441,2088,1163,490,1340,322,420,2103,641,2286,400,238,1583,125 | 0.5492309315430891,-0.7826010790948131,-0.07186090588440568,-1.088736557366239,0.21819012730572218,0.7161283312130348,0.09594659045201429,4.300267789916809,-0.13628593823390364,-1.195379634020793,0.21819012730572218,-0.9844682279779907,-0.2015654664810097,0.624080740847125,-0.2015654664810097,-0.5889493789129632,-0.5652838070018109,-0.49497664277843795,1.7550590252104994,1.414993690331867,-0.1579495805967917,-0.6847954503580282,-0.3800230309908234,0.1574422653969169,0.1574422653969169,-0.7334476908882873,-0.26772543458963366,1.509903867033398,1.2033338913699734,1.0687216574483722,1.1196073499123598,1.462660295599955,1.5567327633064831,0.6978505521998537,-0.09324252520289562,0.03368205509537154,0.2782103405843624,0.7343412937617894,-0.9587584321347755,-0.312334586919792,-0.2455726333366303,-0.6366330002875932,0.47326486642030946,1.2033338913699734,1.8294352882830525,0.45409450442527205,-0.05057146887282142,-0.13628593823390364,2.2006057669567936,1.153258456656166,0.012752580513801317,-0.312334586919792,-0.6127320061884703,0.21819012730572218,0.45409450442527205,0.4155348788904062,0.4348513834489541,0.19802266801457014,-0.2899790727297725,-0.49497664277843795,0.7885964023248992,-0.42567786323215334,0.11652951958878897,0.7343412937617894,0.012752580513801317,1.0516490831696563,0.8244516693582026,-0.42567786323215334,0.5680465845888625,-0.5652838070018109,0.8600596556567248,1.3507652191046324,-0.11471723023422291,1.946353972838871 | 3,040 |
Tclin | 27 | 82 | 2.765638 | 0.005681 | P00374,P21964,P00813,P62942,P49721,Q9P0J0,O43924,P38435,O43676,O75438,P20618,P06280,P03886,P28074,P31350,Q7L0J3,Q99720,Q13547,Q05655,P04350,Q99808,Q06203,Q86Y39,O75306,P68371,O96000,Q9BUF5 | Drugs and Diseases | Pharos IDG Category | pharos_protein_category | 5,387,8,11,142,275,23,407,283,404,154,297,54,312,186,65,69,441,459,332,93,470,355,108,488,118,514 | 1586,283,23,1115,957,108,404,1215,696,1736,118,5,928,1858,8,54,332,2865,1476,805,2689,297,518,1001,2442,2736,806,646,2372,2208,1685,569,2148,887,2039,2618,154,387,824,2666,2445,1559,312,3019,975,186,407,873,3025,142,1968,1659,660,2412,1564,1624,11,488,791,1828,459,470,1037,2768,441,2876,1012,2486,65,355,2916,1238,69,93,2282,514,1074,2430,2256,275,2755,2992 | -0.13628593823390364,1.186695066202737,3.4568631579686766,0.13702781813267018,0.25828324277369913,2.046637516393822,0.8422863325591908,0.07527824008221333,0.4923630858030608,-0.22351964620585527,1.960793573015321,4.300267789916809,0.2782103405843624,-0.2899790727297725,4.115215060881295,2.739511278775411,1.0173354618632569,-1.195379634020793,-0.07186090588440568,0.39614435776678325,-0.907755404541169,1.1364599089502991,0.6795074351426921,0.21819012730572218,-0.6847954503580282,-0.9844682279779907,0.39614435776678325,0.5492309315430891,-0.6366330002875932,-0.5182986952552782,-0.2015654664810097,0.624080740847125,-0.4717666193892306,0.3178291459077337,-0.4027967817372936,-0.8322673872621336,1.7550590252104994,0.8777721115317447,0.3766791785599655,-0.8824588236038856,-0.6847954503580282,-0.11471723023422291,1.0687216574483722,-2.5704306881405343,0.23827674360495169,1.5567327633064831,0.8422863325591908,0.33752223620233285,-2.756611820470718,1.8294352882830525,-0.3573554842529024,-0.17970910315454527,0.5303455219239778,-0.6606536956722414,-0.11471723023422291,-0.1579495805967917,3.8626651909366387,0.7343412937617894,0.4155348788904062,-0.26772543458963366,0.7705748236465301,0.7524899549765799,0.19802266801457014,-1.0103191649269512,0.7885964023248992,-1.2224259209783335,0.21819012730572218,-0.7090596464820835,2.4962294121503965,0.965437543137018,-1.3881021776971274,0.07527824008221333,2.390543045095957,2.145115533980319,-0.5652838070018109,0.6978505521998537,0.1777736295870345,-0.6606536956722414,-0.5417340014635557,1.2199202319870586,-0.9844682279779907,-1.9244726661529046 | 3,040 |
FDA approved drug targets | 30 | 114 | 2.759889 | 0.005782 | Q16637,P00374,P21964,P00813,P62942,P49721,P16615,Q16850,P38435,P21281,P20618,P23786,P35610,P03886,P28074,P31350,Q13423,Q7L0J3,Q14534,Q99720,Q13547,P49356,P05067,Q05655,P31939,P04083,P02786,P20645,Q8N0U8,P68371 | Drugs and Diseases | Protein Atlas Disease involvement | protein_atlas_disease_involvement | 262,5,387,8,11,142,519,18,407,286,154,32,289,54,312,186,60,65,319,69,441,197,74,459,337,467,219,99,494,488 | 2818,996,1111,2636,1115,1371,2974,1328,1739,5,928,1858,1516,8,219,54,467,2596,2865,1476,74,805,1288,2689,2617,2441,518,1001,2777,2848,2442,2736,646,2208,1685,569,867,698,2148,2337,2923,1253,1962,887,1329,2039,519,1654,154,99,286,2079,387,2149,824,32,2666,1559,2081,2930,312,1402,2835,1965,2763,2341,186,337,289,1057,407,907,2795,873,2932,3025,1657,197,142,2265,1060,1660,1334,742,1624,11,488,790,791,1973,1828,1829,459,1037,60,2768,441,319,2218,1832,2454,961,262,826,18,2486,65,494,1238,1176,3000,69,641,2286 | -1.1151699685618548,0.21819012730572218,0.13702781813267018,-0.8572966837718823,0.13702781813267018,-0.008265595708049227,-1.7385416834592708,0.012752580513801317,-0.22351964620585527,4.300267789916809,0.2782103405843624,-0.2899790727297725,-0.09324252520289562,4.115215060881295,1.3829766872888838,2.739511278775411,0.7524899549765799,-0.8073693656405042,-1.195379634020793,-0.07186090588440568,2.2963894486711554,0.39614435776678325,0.03368205509537154,-0.907755404541169,-0.8322673872621336,-0.6847954503580282,0.6795074351426921,0.21819012730572218,-1.0363129992676252,-1.1684895504192612,-0.6847954503580282,-0.9844682279779907,0.5492309315430891,-0.5182986952552782,-0.2015654664810097,0.624080740847125,0.33752223620233285,0.4923630858030608,-0.4717666193892306,-0.6127320061884703,-1.444675674895682,0.0545236662877855,-0.3573554842529024,0.3178291459077337,0.012752580513801317,-0.4027967817372936,0.6795074351426921,-0.17970910315454527,1.7550590252104994,2.089059189581746,1.186695066202737,-0.42567786323215334,0.8777721115317447,-0.4717666193892306,0.3766791785599655,3.196797074340647,-0.8824588236038856,-0.11471723023422291,-0.42567786323215334,-1.4732257420217356,1.0687216574483722,-0.029373324329508732,-1.141753653942985,-0.3573554842529024,-1.0103191649269512,-0.6127320061884703,1.5567327633064831,1.000093579058044,1.170003381143128,0.1777736295870345,0.8422863325591908,0.29805874290970236,-1.062451521523199,0.33752223620233285,-1.4732257420217356,-2.756611820470718,-0.17970910315454527,1.4942024923485768,1.8294352882830525,-0.5652838070018109,0.1777736295870345,-0.17970910315454527,0.012752580513801317,0.45409450442527205,-0.1579495805967917,3.8626651909366387,0.7343412937617894,0.4155348788904062,0.4155348788904062,-0.3573554842529024,-0.26772543458963366,-0.26772543458963366,0.7705748236465301,0.19802266801457014,2.6127834871538127,-1.0103191649269512,0.7885964023248992,1.0516490831696563,-0.5182986952552782,-0.26772543458963366,-0.6847954503580282,0.25828324277369913,1.2693680383752384,0.3766791785599655,3.631156676050709,-0.7090596464820835,2.4962294121503965,0.7343412937617894,0.07527824008221333,0.11652951958878897,-2.052859180393565,2.390543045095957,0.5680465845888625,-0.5652838070018109 | 3,040 |
FDA approved drug targets | 30 | 114 | 2.759889 | 0.005782 | Q16637,P00374,P21964,P00813,P62942,P49721,P16615,Q16850,P38435,P21281,P20618,P23786,P35610,P03886,P28074,P31350,Q13423,Q7L0J3,Q14534,Q99720,Q13547,P49356,P05067,Q05655,P31939,P04083,P02786,P20645,Q8N0U8,P68371 | Functions | Protein Atlas Protein class | protein_atlas_protein_class | 262,5,387,8,11,142,519,18,407,286,154,32,289,54,312,186,60,65,319,69,441,197,74,459,337,467,219,99,494,488 | 2818,996,1111,2636,1115,1371,2974,1328,1739,5,928,1858,1516,8,219,54,467,2596,2865,1476,74,805,1288,2689,2617,2441,518,1001,2777,2848,2442,2736,646,2208,1685,569,867,698,2148,2337,2923,1253,1962,887,1329,2039,519,1654,154,99,286,2079,387,2149,824,32,2666,1559,2081,2930,312,1402,2835,1965,2763,2341,186,337,289,1057,407,907,2795,873,2932,3025,1657,197,142,2265,1060,1660,1334,742,1624,11,488,790,791,1973,1828,1829,459,1037,60,2768,441,319,2218,1832,2454,961,262,826,18,2486,65,494,1238,1176,3000,69,641,2286 | -1.1151699685618548,0.21819012730572218,0.13702781813267018,-0.8572966837718823,0.13702781813267018,-0.008265595708049227,-1.7385416834592708,0.012752580513801317,-0.22351964620585527,4.300267789916809,0.2782103405843624,-0.2899790727297725,-0.09324252520289562,4.115215060881295,1.3829766872888838,2.739511278775411,0.7524899549765799,-0.8073693656405042,-1.195379634020793,-0.07186090588440568,2.2963894486711554,0.39614435776678325,0.03368205509537154,-0.907755404541169,-0.8322673872621336,-0.6847954503580282,0.6795074351426921,0.21819012730572218,-1.0363129992676252,-1.1684895504192612,-0.6847954503580282,-0.9844682279779907,0.5492309315430891,-0.5182986952552782,-0.2015654664810097,0.624080740847125,0.33752223620233285,0.4923630858030608,-0.4717666193892306,-0.6127320061884703,-1.444675674895682,0.0545236662877855,-0.3573554842529024,0.3178291459077337,0.012752580513801317,-0.4027967817372936,0.6795074351426921,-0.17970910315454527,1.7550590252104994,2.089059189581746,1.186695066202737,-0.42567786323215334,0.8777721115317447,-0.4717666193892306,0.3766791785599655,3.196797074340647,-0.8824588236038856,-0.11471723023422291,-0.42567786323215334,-1.4732257420217356,1.0687216574483722,-0.029373324329508732,-1.141753653942985,-0.3573554842529024,-1.0103191649269512,-0.6127320061884703,1.5567327633064831,1.000093579058044,1.170003381143128,0.1777736295870345,0.8422863325591908,0.29805874290970236,-1.062451521523199,0.33752223620233285,-1.4732257420217356,-2.756611820470718,-0.17970910315454527,1.4942024923485768,1.8294352882830525,-0.5652838070018109,0.1777736295870345,-0.17970910315454527,0.012752580513801317,0.45409450442527205,-0.1579495805967917,3.8626651909366387,0.7343412937617894,0.4155348788904062,0.4155348788904062,-0.3573554842529024,-0.26772543458963366,-0.26772543458963366,0.7705748236465301,0.19802266801457014,2.6127834871538127,-1.0103191649269512,0.7885964023248992,1.0516490831696563,-0.5182986952552782,-0.26772543458963366,-0.6847954503580282,0.25828324277369913,1.2693680383752384,0.3766791785599655,3.631156676050709,-0.7090596464820835,2.4962294121503965,0.7343412937617894,0.07527824008221333,0.11652951958878897,-2.052859180393565,2.390543045095957,0.5680465845888625,-0.5652838070018109 | 3,040 |
Mitochondrial transmembrane transport | 12 | 49 | 2.758368 | 0.005809 | P23786,P00846,O60830,Q9BSK2,P21796,O43772,Q9H2D1,Q9UJS0,Q8IYU8,Q9H4I9,Q99595,Q9Y619 | Processes and pathways | GO Biological process | msigdb_gobp | 32,6,10,171,12,44,46,307,372,252,27,125 | 654,675,44,10,2036,1551,1929,2003,378,1251,2881,1436,2688,1189,6,1288,1741,2948,867,698,12,32,1860,2762,871,2954,1060,771,571,2643,1092,502,492,633,372,2813,2555,27,832,171,46,252,1539,2233,1948,307,2585,2295,125 | 0.5303455219239778,0.5113897708571208,2.9606979194992413,3.954821843698463,-0.4027967817372936,-0.11471723023422291,-0.334793033079157,-0.3800230309908234,0.8954241674177924,0.0545236662877855,-1.24963046884146,-0.05057146887282142,-0.907755404541169,0.09594659045201429,4.290668707384786,0.03368205509537154,-0.22351964620585527,-1.5599592297881615,0.33752223620233285,0.4923630858030608,3.8419900405287315,3.196797074340647,-0.2899790727297725,-1.0103191649269512,0.33752223620233285,-1.589240151276104,0.1777736295870345,0.4348513834489541,0.624080740847125,-0.8572966837718823,0.1574422653969169,0.7161283312130348,0.7343412937617894,0.5680465845888625,0.9130162849921596,-1.088736557366239,-0.75796101573055,3.3564837478869274,0.3766791785599655,1.6644326324480352,2.900116777063521,1.3020775180976913,-0.09324252520289562,-0.5182986952552782,-0.334793033079157,1.1027003870412346,-0.7826010790948131,-0.5652838070018109,1.946353972838871 | 3,040 |
Protein catabolic process | 41 | 246 | 2.746218 | 0.006029 | O00560,Q9Y263,Q9UHG3,P49721,P46379,Q9P0J0,Q16850,P53350,P30260,P28072,P49720,Q99538,Q96E52,P20618,Q9UG56,Q96HY6,O94822,Q9NUJ1,P61289,O60502,Q96P47,P28074,O75844,Q9UBS8,P28070,Q92530,O43847,P24941,P60900,Q9UBU6,O75503,Q9UIQ6,Q96K76,Q13190,P10619,Q8N511,Q9UL46,P63244,P04062,P50897,P49427 | Processes and pathways | GO Biological process | msigdb_gobp | 256,139,13,142,15,275,18,145,147,277,278,279,157,154,164,296,166,39,293,50,182,312,58,64,193,322,330,212,85,217,91,97,101,220,103,105,238,114,243,120,119 | 2140,1546,642,713,1470,256,1213,2807,1731,432,2659,1111,1186,841,998,369,842,862,330,2819,50,2702,386,1611,2143,2637,2958,91,2504,1188,58,1886,1930,166,423,2301,1553,1820,1889,2758,645,2664,1738,243,2441,2005,2302,1438,2690,103,2075,2373,1329,1376,2078,2178,1895,154,2939,2834,212,2445,2007,1082,1083,1084,2340,1479,1823,193,277,312,147,483,2824,976,2720,2668,873,1897,1656,15,2620,2669,1790,333,119,278,142,1659,120,1333,1258,1444,1696,145,1035,2852,2766,1593,2344,2213,1936,427,85,2122,2695,293,2885,1335,1900,2346,1795,2511,744,114,1089,2417,1157,776,878,220,1865,2049,2191,1225,2768,2128,2088,1226,2651,1830,1412,2514,1010,1339,1340,1528,2453,1978,1908,1573,1039,1416,18,1634,2221,962,2020,1635,2390,1417,1040,2392,812,725,1872,3009,944,462,2575,827,1495,105,1773,2773,797,1234,1235,1838,2556,322,1237,2165,919,2946,650,2024,474,1143,2226,157,296,855,1501,101,638,182,1576,1310,1777,1174,2493,420,2103,2888,279,1778,1533,496,2494,2679,2680,1538,1146,1206,1315,2323,1428,1641,1642,39,1359,2684,1925,2920,2110,275,64,217,653,164,885,13,2753,97,838,352,951,2787,923,238,1543,1645,819,1583,2433,1465,1607,139,1321,674,1955,994,3001,1026 | 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| 3,040 |
Abnormality of thyroid physiology | 22 | 70 | 2.74552 | 0.006042 | O60313,P21964,P00813,Q13045,Q96RR1,Q9Y263,O14654,O43826,Q9Y3Z3,O95470,Q9Y4P3,P21281,O60566,P16870,P27635,P03886,Q13423,P00403,Q6PGP7,P04066,P61978,P35222 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 377,387,8,265,529,139,516,396,549,405,421,286,287,425,553,54,60,436,340,211,487,483 | 693,1547,516,1322,1214,2033,1957,396,377,287,2703,1886,1820,405,436,8,54,211,846,867,425,286,387,553,2778,483,1562,1896,1966,1378,2548,1445,1483,1447,487,2415,878,573,265,60,2349,1227,2515,1701,2219,1979,1452,1573,340,1496,727,919,2024,1271,855,529,2580,2322,983,1719,1538,1049,2496,2065,819,139,1184,1025,549,421 | 0.4923630858030608,-0.11471723023422291,0.6795074351426921,0.012752580513801317,0.07527824008221333,-0.4027967817372936,-0.3573554842529024,0.8600596556567248,0.8954241674177924,1.170003381143128,-0.9331880544660163,-0.312334586919792,-0.26772543458963366,0.8422863325591908,0.7885964023248992,4.115215060881295,2.739511278775411,1.414993690331867,0.35713869105956414,0.33752223620233285,0.8065551874323789,1.186695066202737,0.8777721115317447,0.6426230676699337,-1.0363129992676252,0.7343412937617894,-0.11471723023422291,-0.312334586919792,-0.3573554842529024,-0.008265595708049227,-0.75796101573055,-0.05057146887282142,-0.07186090588440568,-0.05057146887282142,0.7343412937617894,-0.6606536956722414,0.33752223620233285,0.624080740847125,1.2529369403504902,2.6127834871538127,-0.6127320061884703,0.07527824008221333,-0.7334476908882873,-0.2015654664810097,-0.5182986952552782,-0.3573554842529024,-0.05057146887282142,-0.11471723023422291,1.000093579058044,-0.07186090588440568,0.47326486642030946,0.29805874290970236,-0.3800230309908234,0.0545236662877855,0.35713869105956414,0.6795074351426921,-0.7826010790948131,-0.5889493789129632,0.23827674360495169,-0.2015654664810097,-0.09324252520289562,0.19802266801457014,-0.7090596464820835,-0.4027967817372936,0.39614435776678325,1.8589019195979646,0.11652951958878897,0.21819012730572218,0.661098451902834,0.8244516693582026 | 3,040 |
Steroid binding | 9 | 22 | 2.74274 | 0.006093 | O15118,P21796,P45880,O15173,P04062,Q14108,Q96SU4,Q14849,P35610 | Functions | GO Molecular function | msigdb_gomf | 98,12,14,394,243,52,87,152,289 | 995,98,394,2958,2301,644,243,1476,1518,12,570,2150,289,407,14,2448,52,152,87,596,1878,967 | 0.21819012730572218,2.089059189581746,0.8600596556567248,-1.618710430813493,-0.5889493789129632,0.5492309315430891,1.3183566065504058,-0.07186090588440568,-0.09324252520289562,3.8419900405287315,0.624080740847125,-0.4717666193892306,1.170003381143128,0.8422863325591908,3.810841292230224,-0.6847954503580282,2.7894153625147196,1.7700163914806484,2.2006057669567936,0.6054709229335996,-0.2899790727297725,0.25828324277369913 | 3,040 |
Mitochondrial transport | 32 | 83 | 2.740548 | 0.006134 | P00846,O60830,O14737,P45880,Q9P0J0,Q96EK5,Q8N4H5,Q14849,Q99595,O14925,P23786,Q9Y512,O43772,O43615,P55786,Q9UJS0,Q9UBX3,O95429,O00165,P56134,Q9Y584,Q15070,O75431,Q5JRX3,Q3ZCQ8,O75964,Q9NS69,O43464,Q15388,P62072,P52789,Q10713 | Processes and pathways | GO Biological process | msigdb_gobp | 6,10,643,14,275,272,668,152,27,654,32,565,44,675,47,307,451,311,191,571,72,461,586,349,492,378,107,369,502,117,629,250 | 191,643,654,369,675,44,1285,10,1958,586,1551,2003,378,1251,1151,311,2664,2688,1189,6,1740,1288,1741,2005,1652,2948,867,1895,32,1860,2762,2763,2738,2739,871,2642,14,2954,935,1659,1060,1258,629,47,571,2643,117,1089,250,152,461,502,2927,492,678,349,1836,2392,2095,1574,668,1982,829,272,1310,27,1205,1537,1948,2991,107,275,2031,451,2753,307,2585,2534,2754,565,72,1212,3011 | 1.525559168791652,0.5492309315430891,0.5303455219239778,0.9130162849921596,0.5113897708571208,2.9606979194992413,0.03368205509537154,3.954821843698463,-0.3573554842529024,0.6054709229335996,-0.11471723023422291,-0.3800230309908234,0.8954241674177924,0.0545236662877855,0.11652951958878897,1.0687216574483722,-0.8824588236038856,-0.907755404541169,0.09594659045201429,4.290668707384786,-0.22351964620585527,0.03368205509537154,-0.22351964620585527,-0.3800230309908234,-0.17970910315454527,-1.5599592297881615,0.33752223620233285,-0.312334586919792,3.196797074340647,-0.2899790727297725,-1.0103191649269512,-1.0103191649269512,-0.9844682279779907,-0.9844682279779907,0.33752223620233285,-0.8572966837718823,3.810841292230224,-1.589240151276104,0.2782103405843624,-0.17970910315454527,0.1777736295870345,0.0545236662877855,0.5680465845888625,2.8879227390379008,0.624080740847125,-0.8572966837718823,1.975195006162953,0.1574422653969169,1.3020775180976913,1.7700163914806484,0.7705748236465301,0.7161283312130348,-1.444675674895682,0.7343412937617894,0.5113897708571208,0.982794416200427,-0.26772543458963366,-0.6366330002875932,-0.42567786323215334,-0.11471723023422291,0.5303455219239778,-0.3573554842529024,0.3766791785599655,1.2199202319870586,0.03368205509537154,3.3564837478869274,0.09594659045201429,-0.09324252520289562,-0.334793033079157,-1.9244726661529046,2.0608146287550606,1.2199202319870586,-0.3800230309908234,0.7885964023248992,-0.9844682279779907,1.1027003870412346,-0.7826010790948131,-0.7334476908882873,-0.9844682279779907,0.6426230676699337,2.350387100739699,0.09594659045201429,-2.1850685691959733 | 3,040 |
Cognitive impairment | 38 | 166 | 2.738698 | 0.006168 | O60313,Q03164,Q6DKK2,P21964,P00846,P16278,Q9Y263,P22626,O43826,Q9NQZ5,Q9Y2R0,O95470,P06865,P06280,Q9BQE5,Q9Y487,O75569,Q9UJS0,Q14108,P03886,Q9Y5P6,Q99720,P05067,P07814,P04350,Q9NZJ7,Q9NZ08,Q6PGP7,O75503,P40855,O15118,O75306,P07602,P04062,O43464,P50897,Q10713,Q9Y619 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 377,389,390,387,6,258,139,397,396,144,159,405,291,297,45,177,178,307,52,54,317,69,74,79,332,345,84,340,91,348,98,108,244,243,369,120,250,125 | 693,2788,98,369,1112,1587,396,1285,377,714,2405,108,1327,91,178,1886,1151,2407,405,2688,1189,436,6,1554,54,243,2074,332,1740,74,297,291,604,244,2408,79,3022,2539,1119,2922,846,973,867,258,1688,2307,974,1617,2939,2239,1963,387,2834,397,1559,769,2341,2040,2153,535,2508,1059,348,873,1748,1293,874,627,2309,1657,2798,416,1086,120,2211,2621,2010,2121,536,1525,2344,607,1485,1663,2448,1937,1864,1006,2986,389,2125,2744,1157,878,2550,250,1127,1263,749,2049,1866,52,1413,1699,2515,1599,1701,1668,1911,2929,1303,680,390,1914,340,1068,2518,2351,964,1138,2051,1711,1233,2972,1498,1575,2628,1271,1310,1777,529,2942,2888,899,3000,69,45,2282,1074,1355,1314,479,1540,562,2255,144,988,2356,2496,84,345,689,1813,691,885,307,819,2032,139,159,177,2295,970,317,2403,125 | 0.4923630858030608,-1.062451521523199,2.089059189581746,0.9130162849921596,0.13702781813267018,-0.13628593823390364,0.8600596556567248,0.03368205509537154,0.8954241674177924,0.47326486642030946,-0.6606536956722414,2.046637516393822,0.012752580513801317,2.1590406610189636,1.6338813250114639,-0.312334586919792,0.11652951958878897,-0.6606536956722414,0.8422863325591908,-0.907755404541169,0.09594659045201429,0.7885964023248992,4.290668707384786,-0.11471723023422291,2.739511278775411,1.3183566065504058,-0.42567786323215334,1.0173354618632569,-0.22351964620585527,2.2963894486711554,1.1364599089502991,1.153258456656166,0.5867930584046154,1.3183566065504058,-0.6606536956722414,2.269191783909705,-2.607117761422336,-0.75796101573055,0.13702781813267018,-1.444675674895682,0.35713869105956414,0.23827674360495169,0.33752223620233285,1.2693680383752384,-0.2015654664810097,-0.5889493789129632,0.23827674360495169,-0.1579495805967917,-1.5019546528638092,-0.5417340014635557,-0.3573554842529024,0.8777721115317447,-1.141753653942985,0.8600596556567248,-0.11471723023422291,0.4348513834489541,-0.6127320061884703,-0.4027967817372936,-0.4717666193892306,0.661098451902834,-0.7334476908882873,0.1777736295870345,0.982794416200427,0.33752223620233285,-0.22351964620585527,0.03368205509537154,0.33752223620233285,0.5680465845888625,-0.5889493789129632,-0.17970910315454527,-1.062451521523199,0.8244516693582026,0.1574422653969169,1.960793573015321,-0.5182986952552782,-0.8322673872621336,-0.3800230309908234,-0.44866742092299217,0.661098451902834,-0.09324252520289562,-0.6127320061884703,0.5867930584046154,-0.07186090588440568,-0.17970910315454527,-0.6847954503580282,-0.334793033079157,-0.2899790727297725,0.21819012730572218,-1.8616370106422162,0.8777721115317447,-0.44866742092299217,-0.9844682279779907,0.11652951958878897,0.33752223620233285,-0.75796101573055,1.3020775180976913,0.13702781813267018,0.0545236662877855,0.45409450442527205,-0.4027967817372936,-0.2899790727297725,2.7894153625147196,-0.029373324329508732,-0.2015654664810097,-0.7334476908882873,-0.13628593823390364,-0.2015654664810097,-0.17970910315454527,-0.312334586919792,-1.444675674895682,0.03368205509537154,0.5113897708571208,0.8777721115317447,-0.312334586919792,1.000093579058044,0.1777736295870345,-0.7334476908882873,-0.6127320061884703,0.25828324277369913,0.13702781813267018,-0.4027967817372936,-0.2015654664810097,0.07527824008221333,-1.7082855307060512,-0.07186090588440568,-0.11471723023422291,-0.8322673872621336,0.0545236662877855,0.03368205509537154,-0.22351964620585527,0.6795074351426921,-1.5019546528638092,-1.24963046884146,0.3178291459077337,-2.052859180393565,2.390543045095957,2.9606979194992413,-0.5652838070018109,0.1777736295870345,0.012752580513801317,0.03368205509537154,0.7524899549765799,-0.09324252520289562,0.6426230676699337,-0.5417340014635557,1.8294352882830525,0.23827674360495169,-0.6127320061884703,-0.7090596464820835,2.214391369466817,1.000093579058044,0.5113897708571208,-0.2455726333366303,0.5113897708571208,0.33752223620233285,1.1027003870412346,0.39614435776678325,-0.3800230309908234,1.8589019195979646,1.7550590252104994,1.649178704645811,-0.5652838070018109,0.25828324277369913,1.0687216574483722,-0.6366330002875932,1.946353972838871 | 3,040 |
Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1 | 14 | 46 | 2.733501 | 0.006266 | P20618,Q92530,P28070,Q9UJX3,P61289,P49721,Q9UL46,P53350,P30260,P28072,P49720,P60900,P28074,Q99436 | Processes and pathways | Reactome Pathways | msigdb_reactome | 154,322,193,352,293,142,238,145,147,277,278,85,312,420 | 642,2564,1470,2807,432,998,1188,2178,154,2445,2007,1082,1083,1823,193,277,312,147,2720,1897,1790,278,142,1444,145,1593,85,293,1335,1900,2346,776,1865,2191,1340,1416,322,541,420,2103,1538,838,352,951,238,1583 | 0.5492309315430891,-0.7826010790948131,-0.07186090588440568,-1.088736557366239,0.7885964023248992,0.21819012730572218,0.09594659045201429,-0.49497664277843795,1.7550590252104994,-0.6847954503580282,-0.3800230309908234,0.1574422653969169,0.1574422653969169,-0.26772543458963366,1.509903867033398,1.2033338913699734,1.0687216574483722,1.799807445284277,-0.9587584321347755,-0.312334586919792,-0.2455726333366303,1.2033338913699734,1.8294352882830525,-0.05057146887282142,1.8146416422908467,-0.13628593823390364,2.2006057669567936,1.153258456656166,0.012752580513801317,-0.312334586919792,-0.6127320061884703,0.4348513834489541,-0.2899790727297725,-0.49497664277843795,0.012752580513801317,-0.029373324329508732,1.0516490831696563,0.661098451902834,0.8244516693582026,-0.42567786323215334,-0.09324252520289562,0.3766791785599655,0.982794416200427,0.2782103405843624,1.3507652191046324,-0.11471723023422291 | 3,040 |
Steroid metabolic process | 19 | 65 | 2.729505 | 0.006343 | Q15392,Q16850,Q6P1A2,Q99538,Q14849,P16435,P35610,Q8WTV0,Q9BQE5,Q14739,Q15800,P37268,Q14534,P05067,Q06520,Q96SU4,O15118,P04062,P48449 | Processes and pathways | GO Biological process | msigdb_gobp | 7,18,151,279,152,285,289,41,45,173,179,53,319,74,203,87,98,243,245 | 454,98,2958,2301,405,1614,243,1476,74,2777,1153,887,2039,285,570,2150,1003,2976,534,289,53,407,3026,2642,245,2479,2621,2010,1660,742,2448,2625,2874,662,203,1866,1800,319,173,152,1264,491,2484,7,2672,2275,2978,179,18,321,2934,151,1018,41,87,279,3000,45,1314,1461,967,690,2584,1361,819 | 0.7705748236465301,2.089059189581746,-1.618710430813493,-0.5889493789129632,0.8422863325591908,-0.1579495805967917,1.3183566065504058,-0.07186090588440568,2.2963894486711554,-1.0363129992676252,0.11652951958878897,0.3178291459077337,-0.4027967817372936,1.186695066202737,0.624080740847125,-0.4717666193892306,0.21819012730572218,-1.7385416834592708,0.661098451902834,1.170003381143128,2.776980594626845,0.8422863325591908,-2.832999263059134,-0.8572966837718823,1.3183566065504058,-0.7090596464820835,-0.8322673872621336,-0.3800230309908234,-0.17970910315454527,0.45409450442527205,-0.6847954503580282,-0.8322673872621336,-1.2224259209783335,0.5303455219239778,1.462660295599955,-0.2899790727297725,-0.2455726333366303,1.0516490831696563,1.649178704645811,1.7700163914806484,0.0545236662877855,0.7343412937617894,-0.7090596464820835,4.164468347330218,-0.8824588236038856,-0.5652838070018109,-1.7690017501469077,1.6185402139192084,3.631156676050709,1.0516490831696563,-1.4732257420217356,1.7849324461832374,0.21819012730572218,3.032555550251405,2.2006057669567936,1.2033338913699734,-2.052859180393565,2.9606979194992413,0.03368205509537154,-0.05057146887282142,0.25828324277369913,0.5113897708571208,-0.7826010790948131,0.012752580513801317,0.39614435776678325 | 3,040 |
Alcohol binding | 6 | 18 | 2.726232 | 0.006406 | O15118,P21796,P45880,Q14108,Q14849,P09455 | Functions | GO Molecular function | msigdb_gomf | 98,12,14,52,152,63 | 517,98,1399,2958,2301,644,1518,63,12,2150,1290,289,14,2448,52,152,1878,967 | 0.6795074351426921,2.089059189581746,-0.029373324329508732,-1.618710430813493,-0.5889493789129632,0.5492309315430891,-0.09324252520289562,2.574201082420162,3.8419900405287315,-0.4717666193892306,0.03368205509537154,1.170003381143128,3.810841292230224,-0.6847954503580282,2.7894153625147196,1.7700163914806484,-0.2899790727297725,0.25828324277369913 | 3,040 |
Gait ataxia | 10 | 64 | 2.725693 | 0.006417 | Q9NR77,O15118,P00846,P04350,P41440,P07602,Q14108,P03886,Q10713,Q8IV08 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 2,98,6,332,239,244,52,54,250,29 | 2176,1368,1213,2788,98,1549,1112,765,6,54,332,604,1961,244,1686,867,1962,1688,974,1894,1617,1003,2179,553,1520,2341,2850,1523,239,1293,1694,2084,2621,2010,1525,1483,1262,878,250,2049,1830,52,2515,1599,1833,503,1492,29,2051,579,756,2727,529,899,1355,2,1725,1580,345,689,1813,2235,819,2295 | -0.49497664277843795,-0.008265595708049227,0.07527824008221333,-1.062451521523199,2.089059189581746,-0.11471723023422291,0.13702781813267018,0.4348513834489541,4.290668707384786,2.739511278775411,1.0173354618632569,0.5867930584046154,-0.3573554842529024,1.3183566065504058,-0.2015654664810097,0.33752223620233285,-0.3573554842529024,-0.2015654664810097,0.23827674360495169,-0.312334586919792,-0.1579495805967917,0.21819012730572218,-0.49497664277843795,0.6426230676699337,-0.09324252520289562,-0.6127320061884703,-1.1684895504192612,-0.09324252520289562,1.3345857255664315,0.03368205509537154,-0.2015654664810097,-0.42567786323215334,-0.8322673872621336,-0.3800230309908234,-0.09324252520289562,-0.07186090588440568,0.0545236662877855,0.33752223620233285,1.3020775180976913,-0.4027967817372936,-0.26772543458963366,2.7894153625147196,-0.7334476908882873,-0.13628593823390364,-0.26772543458963366,0.7161283312130348,-0.07186090588440568,3.2657753202833986,-0.4027967817372936,0.624080740847125,0.45409450442527205,-0.9587584321347755,0.6795074351426921,0.3178291459077337,0.012752580513801317,4.599675697788404,-0.2015654664810097,-0.11471723023422291,1.000093579058044,0.5113897708571208,-0.2455726333366303,-0.5182986952552782,0.39614435776678325,-0.5652838070018109 | 3,040 |
Tetrapyrrole binding | 8 | 16 | 2.719503 | 0.006538 | Q6UW02,P30519,Q9NRV9,Q16850,O43169,Q8WUJ1,Q7KZN9,P09601 | Functions | GO Molecular function | msigdb_gomf | 294,70,200,18,83,88,381,284 | 995,394,83,2237,284,2149,70,521,18,294,381,88,2197,1176,707,200 | 0.21819012730572218,0.8600596556567248,2.214391369466817,-0.5417340014635557,1.186695066202737,-0.4717666193892306,2.377189975700653,0.6795074351426921,3.631156676050709,1.153258456656166,0.8954241674177924,2.1729306095374197,-0.49497664277843795,0.11652951958878897,0.4923630858030608,1.4942024923485768 | 3,040 |
Aminoglycan metabolic process | 8 | 17 | 2.715924 | 0.006609 | Q7LGA3,P08236,O60701,P16278,P06865,Q8NCH0,P04066,O43505 | Processes and pathways | GO Biological process | msigdb_gobp | 222,192,218,258,291,170,211,185 | 185,218,1373,211,291,2408,192,888,258,536,1864,1631,222,170,327,2396,1990 | 1.5567327633064831,1.3829766872888838,-0.008265595708049227,1.414993690331867,1.153258456656166,-0.6606536956722414,1.525559168791652,0.3178291459077337,1.2693680383752384,0.661098451902834,-0.2899790727297725,-0.1579495805967917,1.3829766872888838,1.6644326324480352,1.0345204898018696,-0.6366330002875932,-0.3573554842529024 | 3,040 |
Abnormal lower limb bone morphology | 41 | 152 | 2.711024 | 0.006708 | Q03164,P21964,Q15392,P00813,P16278,Q9BV10,Q9Y263,O43924,P16435,P21281,O96028,Q6NUQ1,Q96HY6,Q9NXE4,P06280,O43909,Q9Y487,Q14739,Q99567,Q13555,O43505,O75844,P08236,Q08AM6,Q96L58,Q9H9E3,Q9NUQ7,Q9NZJ7,Q93009,Q9Y4W2,P04066,O75530,O96019,Q7LGA3,Q96AY3,Q15125,P07602,P04062,Q5H8A4,Q10713,Q9Y619 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 389,387,7,8,258,138,139,23,285,286,161,162,296,431,297,422,177,173,306,309,185,58,192,460,327,464,205,345,474,481,211,215,346,222,359,491,244,243,503,250,125 | 972,2564,1547,2362,1368,1322,600,694,624,185,422,23,1550,2998,2001,2846,498,586,215,844,551,58,1820,2881,2594,2688,1738,346,161,8,2073,243,211,1740,297,244,192,846,1891,258,285,974,2719,286,2939,2239,387,2375,1964,2543,1402,2619,2982,2343,908,1293,2913,1694,1086,2621,1379,2836,1899,1445,1624,2671,2183,877,389,1262,1299,878,460,777,792,250,1629,1866,309,1830,1301,1010,2515,173,1700,1867,491,7,1869,1131,1134,503,2019,2316,1835,1015,162,964,880,222,2391,2392,1346,1711,2812,1713,919,1601,2024,474,1143,359,296,327,1043,2580,2942,306,580,2859,138,670,1538,1847,1315,2393,1721,1539,464,1540,2713,2681,205,1049,2944,1990,431,345,690,860,1582,2258,2032,139,2399,2329,177,820,481,1365,2589,125 | 0.23827674360495169,-0.7826010790948131,-0.11471723023422291,-0.6366330002875932,-0.008265595708049227,0.012752580513801317,0.5867930584046154,0.4923630858030608,0.5680465845888625,1.5567327633064831,0.8065551874323789,3.4568631579686766,-0.11471723023422291,-2.052859180393565,-0.3800230309908234,-1.1684895504192612,0.7161283312130348,0.6054709229335996,1.3990093317163634,0.35713869105956414,0.6426230676699337,2.676504066166205,-0.26772543458963366,-1.24963046884146,-0.8073693656405042,-0.907755404541169,-0.22351964620585527,0.982794416200427,1.7250193216134055,4.115215060881295,-0.42567786323215334,1.3183566065504058,1.414993690331867,-0.22351964620585527,1.1364599089502991,1.3183566065504058,1.525559168791652,0.35713869105956414,-0.312334586919792,1.2693680383752384,1.186695066202737,0.23827674360495169,-0.9587584321347755,1.186695066202737,-1.5019546528638092,-0.5417340014635557,0.8777721115317447,-0.6366330002875932,-0.3573554842529024,-0.75796101573055,-0.029373324329508732,-0.8322673872621336,-1.7996688507524958,-0.6127320061884703,0.29805874290970236,0.03368205509537154,-1.3881021776971274,-0.2015654664810097,0.1574422653969169,-0.8322673872621336,-0.008265595708049227,-1.141753653942985,-0.312334586919792,-0.05057146887282142,-0.1579495805967917,-0.8824588236038856,-0.49497664277843795,0.33752223620233285,0.8777721115317447,0.0545236662877855,0.03368205509537154,0.33752223620233285,0.7705748236465301,0.4348513834489541,0.4155348788904062,1.3020775180976913,-0.1579495805967917,-0.2899790727297725,1.0857386233802766,-0.26772543458963366,0.03368205509537154,0.21819012730572218,-0.7334476908882873,1.649178704645811,-0.2015654664810097,-0.2899790727297725,0.7343412937617894,4.164468347330218,-0.2899790727297725,0.13702781813267018,0.13702781813267018,0.7161283312130348,-0.3800230309908234,-0.5889493789129632,-0.26772543458963366,0.21819012730572218,1.7250193216134055,0.25828324277369913,0.33752223620233285,1.3829766872888838,-0.6366330002875932,-0.6366330002875932,0.012752580513801317,-0.2015654664810097,-1.088736557366239,-0.2015654664810097,0.29805874290970236,-0.13628593823390364,-0.3800230309908234,0.7524899549765799,0.13702781813267018,0.965437543137018,1.153258456656166,1.0345204898018696,0.19802266801457014,-0.7826010790948131,-1.5019546528638092,1.1027003870412346,0.624080740847125,-1.1684895504192612,1.8735753952262877,0.5303455219239778,-0.09324252520289562,-0.26772543458963366,0.03368205509537154,-0.6366330002875932,-0.2015654664810097,-0.09324252520289562,0.7705748236465301,-0.09324252520289562,-0.9331880544660163,-0.8824588236038856,1.462660295599955,0.19802266801457014,-1.5019546528638092,-0.3573554842529024,0.8065551874323789,1.000093579058044,0.5113897708571208,0.35713869105956414,-0.11471723023422291,-0.5417340014635557,-0.3800230309908234,1.8589019195979646,-0.6366330002875932,-0.5889493789129632,1.649178704645811,0.39614435776678325,0.7524899549765799,0.012752580513801317,-0.7826010790948131,1.946353972838871 | 3,040 |
Cation transmembrane transport | 20 | 112 | 2.703824 | 0.006855 | P78417,P00846,P62942,P21796,O00400,P21281,Q70HW3,Q9HD20,O43772,Q9HC07,Q9HD47,Q13423,P05067,Q9UDW1,Q96GC9,Q8IYU8,Q9P246,O75964,Q9H4I9,Q9Y619 | Processes and pathways | GO Biological process | msigdb_gobp | 130,6,11,12,20,286,33,40,44,175,176,60,74,234,374,372,248,378,252,125 | 20,1586,2590,1150,44,2299,2036,957,2662,1551,2003,378,2881,1684,436,6,1476,74,1288,2689,1741,2441,1961,1518,1081,2237,806,2822,1153,867,1891,519,1616,1654,1558,286,2079,2939,12,1860,2762,406,1786,2763,2545,1123,2896,871,2508,1059,1293,1480,2954,1863,469,1564,1624,571,2643,2268,1663,1449,11,130,790,1092,811,662,878,2966,60,2891,1197,1764,2454,2518,33,381,594,372,1772,504,2813,2607,557,374,1173,1576,2888,2775,2229,832,1504,1675,2611,1721,252,1539,2233,175,708,40,176,248,234,710,1509,2585,1363,1584,2295,125 | 3.5772458059331473,-0.13628593823390364,-0.8073693656405042,0.11652951958878897,2.9606979194992413,-0.5889493789129632,-0.4027967817372936,0.25828324277369913,-0.8824588236038856,-0.11471723023422291,-0.3800230309908234,0.8954241674177924,-1.24963046884146,-0.2015654664810097,0.7885964023248992,4.290668707384786,-0.07186090588440568,2.2963894486711554,0.03368205509537154,-0.907755404541169,-0.22351964620585527,-0.6847954503580282,-0.3573554842529024,-0.09324252520289562,0.1574422653969169,-0.5417340014635557,0.39614435776678325,-1.1151699685618548,0.11652951958878897,0.33752223620233285,-0.312334586919792,0.6795074351426921,-0.1579495805967917,-0.17970910315454527,-0.11471723023422291,1.186695066202737,-0.42567786323215334,-1.5019546528638092,3.8419900405287315,-0.2899790727297725,-1.0103191649269512,0.8422863325591908,-0.2455726333366303,-1.0103191649269512,-0.75796101573055,0.13702781813267018,-1.3045227910643165,0.33752223620233285,-0.7334476908882873,0.1777736295870345,0.03368205509537154,-0.07186090588440568,-1.589240151276104,-0.2899790727297725,0.7524899549765799,-0.11471723023422291,-0.1579495805967917,0.624080740847125,-0.8572966837718823,-0.5652838070018109,-0.17970910315454527,-0.05057146887282142,3.8626651909366387,1.9028038748611003,0.4155348788904062,0.1574422653969169,0.39614435776678325,0.5303455219239778,0.33752223620233285,-1.6483728475080308,2.6127834871538127,-1.2769953776362524,0.09594659045201429,-0.22351964620585527,-0.6847954503580282,-0.7334476908882873,3.1619957827526095,0.8954241674177924,0.6054709229335996,0.9130162849921596,-0.22351964620585527,0.7161283312130348,-1.088736557366239,-0.8073693656405042,0.6426230676699337,0.9130162849921596,0.11652951958878897,-0.11471723023422291,-1.24963046884146,-1.0103191649269512,-0.5182986952552782,0.3766791785599655,-0.07186090588440568,-0.17970910315454527,-0.8073693656405042,-0.2015654664810097,1.3020775180976913,-0.09324252520289562,-0.5182986952552782,1.649178704645811,0.4923630858030608,3.0444444324111646,1.649178704645811,1.3183566065504058,1.366895427454461,0.4923630858030608,-0.07186090588440568,-0.7826010790948131,0.012752580513801317,-0.11471723023422291,-0.5652838070018109,1.946353972838871 | 3,040 |
Terpenoid metabolic process | 8 | 19 | 2.699728 | 0.00694 | O94788,Q9HBH5,Q6NUM9,Q9BY49,P48449,P37268,Q9HB40,P09455 | Processes and pathways | GO Biological process | msigdb_gobp | 134,232,266,210,245,53,121,63 | 369,533,134,63,1219,887,2039,1290,53,245,659,2874,266,681,1774,210,121,232,803 | 0.9130162849921596,0.661098451902834,1.8735753952262877,2.574201082420162,0.07527824008221333,0.3178291459077337,-0.4027967817372936,0.03368205509537154,2.776980594626845,1.3183566065504058,0.5303455219239778,-1.2224259209783335,1.2529369403504902,0.5113897708571208,-0.22351964620585527,1.4309300892669885,1.960793573015321,1.366895427454461,0.4155348788904062 | 3,040 |
Protein methyltransferase activity | 7 | 22 | 2.687634 | 0.007196 | O60725,O96028,Q03164,Q6P2P2,Q9BV86,O75530,O60678 | Functions | GO Molecular function | msigdb_gomf | 0,161,389,113,22,215,533 | 1248,533,0,215,161,2691,1401,1061,389,1451,793,1065,1943,113,963,539,1388,2253,966,22,1427,837 | 0.0545236662877855,0.661098451902834,4.663254621455635,1.3990093317163634,1.7250193216134055,-0.907755404541169,-0.029373324329508732,0.1777736295870345,0.8777721115317447,-0.05057146887282142,0.4155348788904062,0.1777736295870345,-0.334793033079157,2.00388427468888,0.25828324277369913,0.661098451902834,-0.008265595708049227,-0.5417340014635557,0.25828324277369913,3.4679102419726933,-0.029373324329508732,0.3766791785599655 | 3,040 |
Carbohydrate derivative transport | 10 | 19 | 2.687224 | 0.007205 | Q8WTV0,O43826,Q9NZJ7,P41440,P07602,O00400,Q8N697,Q9HC21,Q99808,Q8TB61 | Processes and pathways | GO Biological process | msigdb_gobp | 41,396,345,239,244,20,504,708,93,540 | 1468,20,1370,396,1288,244,867,698,239,2448,1628,1836,504,540,798,41,93,708,345 | -0.07186090588440568,3.5772458059331473,-0.008265595708049227,0.8600596556567248,0.03368205509537154,1.3183566065504058,0.33752223620233285,0.4923630858030608,1.3345857255664315,-0.6847954503580282,-0.1579495805967917,-0.26772543458963366,0.7161283312130348,0.661098451902834,0.4155348788904062,3.032555550251405,2.145115533980319,0.4923630858030608,1.000093579058044 | 3,040 |
Ub specific processing proteases | 14 | 63 | 2.683857 | 0.007278 | P28070,Q96K76,P61289,P21796,Q9Y277,P49721,P45880,Q9UL46,Q96FW1,P28072,P49720,P60900,P28074,P20618 | Processes and pathways | Reactome Pathways | msigdb_reactome | 193,101,293,12,206,142,14,238,149,277,278,85,312,154 | 642,2564,1470,2807,1731,998,2819,1188,1251,1553,1740,1329,2178,154,12,2445,2007,1082,1083,1823,193,277,312,2720,1897,14,1656,1790,278,142,1444,1696,2852,1593,85,293,1335,1900,2346,776,1865,2191,1976,1339,1340,502,3032,725,1574,322,919,2024,474,149,101,420,2103,2685,238,1583,1679,206,1025 | 0.5492309315430891,-0.7826010790948131,-0.07186090588440568,-1.088736557366239,-0.22351964620585527,0.21819012730572218,-1.1151699685618548,0.09594659045201429,0.0545236662877855,-0.11471723023422291,-0.22351964620585527,0.012752580513801317,-0.49497664277843795,1.7550590252104994,3.8419900405287315,-0.6847954503580282,-0.3800230309908234,0.1574422653969169,0.1574422653969169,-0.26772543458963366,1.509903867033398,1.2033338913699734,1.0687216574483722,-0.9587584321347755,-0.312334586919792,3.810841292230224,-0.17970910315454527,-0.2455726333366303,1.2033338913699734,1.8294352882830525,-0.05057146887282142,-0.2015654664810097,-1.1684895504192612,-0.13628593823390364,2.2006057669567936,1.153258456656166,0.012752580513801317,-0.312334586919792,-0.6127320061884703,0.4348513834489541,-0.2899790727297725,-0.49497664277843795,-0.3573554842529024,0.012752580513801317,0.012752580513801317,0.7161283312130348,-3.4829683632515382,0.47326486642030946,-0.11471723023422291,1.0516490831696563,0.29805874290970236,-0.3800230309908234,0.7524899549765799,1.799807445284277,2.089059189581746,0.8244516693582026,-0.42567786323215334,-0.8824588236038856,1.3507652191046324,-0.11471723023422291,-0.17970910315454527,1.462660295599955,0.21819012730572218 | 3,040 |
Ceramide metabolic process | 13 | 19 | 2.681035 | 0.007339 | Q96G23,O15269,Q9NXE4,P06865,P06280,P30153,Q99805,Q05655,Q8NCC3,O43464,P04062,O95470,O15270 | Processes and pathways | GO Biological process | msigdb_gobp | 263,165,431,291,297,299,618,459,17,369,243,405,655 | 1854,165,655,369,405,243,297,291,2408,2307,769,299,459,1866,678,17,263,618,431 | -0.2899790727297725,1.7099364597647162,0.5303455219239778,0.9130162849921596,0.8422863325591908,1.3183566065504058,1.1364599089502991,1.153258456656166,-0.6606536956722414,-0.5889493789129632,0.4348513834489541,1.1196073499123598,0.7705748236465301,-0.2899790727297725,0.5113897708571208,3.748046944176162,1.2693680383752384,0.5867930584046154,0.8065551874323789 | 3,040 |
Vesicles | 65 | 299 | 2.677429 | 0.007419 | P24390,P21964,P40938,O60826,P16278,Q8NBX0,O60506,Q8NCC3,O95302,O00400,Q99538,Q14849,P27105,P16435,P21281,P18858,P42785,O95070,Q9HD20,Q8WTV0,Q86WC4,Q86YN1,P06865,Q96RQ1,P16870,A1L0T0,Q9Y487,Q15363,Q9UMR5,Q9UJ14,Q9BPZ3,P35613,Q8N128,Q93050,P11717,P08236,Q14534,O75312,P30519,Q9NRV9,Q08AM6,P05067,Q8N8N7,O14734,O75153,Q96SU4,P04066,Q9H2V7,Q9NUD5,Q5KU26,Q9NRY5,O15118,Q96K76,Q9HD45,P10619,Q8TBQ9,Q9NPR9,Q92564,P07602,Q96L92,P50897,Q13277,Q3SXM5,Q8TCT8,Q96SK2 | Localization | Protein Atlas Subcellular | protein_atlas_subcellular_location_all | 1,387,388,386,258,9,385,17,270,20,279,152,406,285,286,288,36,414,40,41,168,43,291,301,425,303,177,443,453,180,57,313,445,323,438,192,319,435,70,200,460,74,334,454,82,87,211,478,90,350,96,98,101,102,103,356,111,109,244,246,120,371,251,123,254 | 303,20,693,1547,713,1368,454,2201,1471,764,1111,2788,955,98,1784,601,1732,1433,2114,2660,1113,2833,385,386,603,82,2405,435,2143,1032,1734,1888,2439,414,270,2407,2072,644,1373,1739,211,2596,74,291,244,192,1375,2598,2821,2690,646,103,2075,438,2076,1687,2262,2306,258,285,425,2307,288,2912,286,387,1,1655,1083,406,1519,70,508,1747,2507,313,1254,3026,1059,388,2182,873,2410,36,627,2310,1332,2044,1563,1694,909,935,1592,2378,120,469,1752,2121,629,2046,2743,589,1482,1035,2212,1445,1624,937,2808,2380,1662,608,774,2449,1664,745,1864,1156,2271,2416,2188,1628,460,1094,1526,2918,2216,371,1632,2315,2650,1572,1038,2350,2089,2217,319,2193,1761,152,2050,1907,1264,2900,2652,2653,443,2517,2158,2927,1833,2194,1134,251,1871,1943,678,1066,911,2019,2195,350,752,1912,2770,2934,1015,2699,633,2771,1803,2520,1137,3027,1419,538,168,726,43,1872,1201,1770,445,1139,918,1169,1981,334,1983,9,2972,1388,17,2877,2995,540,356,123,41,2964,1235,2577,2459,109,1775,2675,2165,617,2024,323,731,2425,948,557,1776,1532,855,1501,101,732,246,2608,705,2750,301,254,87,1144,279,2199,2229,57,1639,1533,816,2105,2678,1100,2610,1878,858,1355,640,546,1538,1314,478,1315,1880,903,1724,40,102,2200,2786,111,2234,2061,988,200,96,2027,90,1949,1209,1925,3021,2561,1105,2499,1813,2733,1360,2359,2235,180,1541,2288,3038,2586,2290,923,453,2066,2952,1053,2258,1397,969,2401,177,1076,1283,970,3015,3001,1026,1512,2068 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| 3,040 |
Serine hydrolase activity | 8 | 17 | 2.676953 | 0.00743 | P42785,Q9H3G5,P10619,O75976,O43464,Q9HB40,Q5JRX3,Q4J6C6 | Functions | GO Molecular function | msigdb_gomf | 36,4,103,298,369,121,349,61 | 1213,369,298,103,2304,626,2668,36,457,719,1035,746,1039,61,349,4,121 | 0.07527824008221333,0.9130162849921596,1.1196073499123598,2.074955115714817,-0.5889493789129632,0.5680465845888625,-0.8824588236038856,3.1152639138541405,0.7705748236465301,0.47326486642030946,0.19802266801457014,0.45409450442527205,0.19802266801457014,2.599952157387,0.982794416200427,4.309851630842509,1.960793573015321 | 3,040 |
Degradation of beta catenin by the destruction complex | 15 | 46 | 2.674306 | 0.007488 | P20618,Q92530,P28070,Q13547,P61289,P30153,P30154,P48729,P49721,Q9UL46,P28072,P49720,P60900,P28074,Q99436 | Processes and pathways | Reactome Pathways | msigdb_reactome | 154,322,193,441,293,299,202,333,142,238,277,278,85,312,420 | 642,2564,1470,2807,998,1188,2178,154,2445,2007,1082,1083,1823,193,277,312,299,202,483,2720,1897,1790,333,278,142,1659,1444,1593,1484,85,293,1335,1900,2346,744,776,1865,441,2088,1062,1340,322,420,2103,238,1583 | 0.5492309315430891,-0.7826010790948131,-0.07186090588440568,-1.088736557366239,0.21819012730572218,0.09594659045201429,-0.49497664277843795,1.7550590252104994,-0.6847954503580282,-0.3800230309908234,0.1574422653969169,0.1574422653969169,-0.26772543458963366,1.509903867033398,1.2033338913699734,1.0687216574483722,1.1196073499123598,1.462660295599955,0.7343412937617894,-0.9587584321347755,-0.312334586919792,-0.2455726333366303,1.0173354618632569,1.2033338913699734,1.8294352882830525,-0.17970910315454527,-0.05057146887282142,-0.13628593823390364,-0.07186090588440568,2.2006057669567936,1.153258456656166,0.012752580513801317,-0.312334586919792,-0.6127320061884703,0.45409450442527205,0.4348513834489541,-0.2899790727297725,0.7885964023248992,-0.42567786323215334,0.1777736295870345,0.012752580513801317,1.0516490831696563,0.8244516693582026,-0.42567786323215334,1.3507652191046324,-0.11471723023422291 | 3,040 |
Alcohol biosynthetic process | 10 | 36 | 2.669862 | 0.007588 | O15269,P00374,Q15392,Q14739,Q16850,Q15800,P04062,P37268,Q6P1A2,P48449 | Processes and pathways | GO Biological process | msigdb_gobp | 165,5,7,173,18,179,243,53,151,245 | 2714,165,655,2958,2301,5,1614,243,2539,1153,887,285,2006,2153,53,2642,245,1660,742,743,2874,1866,1800,173,491,2484,7,2978,179,18,151,1138,2888,1314,2633,690 | -0.9587584321347755,1.7099364597647162,0.5303455219239778,-1.618710430813493,-0.5889493789129632,4.300267789916809,-0.1579495805967917,1.3183566065504058,-0.75796101573055,0.11652951958878897,0.3178291459077337,1.186695066202737,-0.3800230309908234,-0.4717666193892306,2.776980594626845,-0.8572966837718823,1.3183566065504058,-0.17970910315454527,0.45409450442527205,0.45409450442527205,-1.2224259209783335,-0.2899790727297725,-0.2455726333366303,1.649178704645811,0.7343412937617894,-0.7090596464820835,4.164468347330218,-1.7690017501469077,1.6185402139192084,3.631156676050709,1.7849324461832374,0.13702781813267018,-1.24963046884146,0.03368205509537154,-0.8322673872621336,0.5113897708571208 | 3,040 |
Splenomegaly | 23 | 85 | 2.659582 | 0.007824 | P21964,Q15392,P00813,P16278,P14174,P21281,Q6NUQ1,Q96HY6,Q86WC4,P36551,Q14739,Q14108,P08236,P28070,Q9H9E3,Q9NZJ7,Q9NZ08,Q6PGP7,P04066,O15118,P07602,P04062,Q10713 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 387,7,8,258,276,286,162,296,168,426,173,52,192,193,464,345,84,340,211,98,244,243,250 | 1609,1547,1368,2844,600,98,1399,2502,2204,766,2703,864,1858,8,1554,2073,243,211,2847,1740,1517,1289,2717,244,192,646,973,1252,2372,1153,2639,276,888,258,1377,1744,286,387,2149,2340,193,534,626,1522,426,2931,3026,1657,2548,2010,1379,1445,2267,536,2808,2448,1299,459,250,1974,1866,52,173,7,1979,941,162,340,2279,168,919,2725,1143,1272,296,855,1777,545,2731,1675,464,2612,836,84,345 | -0.1579495805967917,-0.11471723023422291,-0.008265595708049227,-1.1684895504192612,0.5867930584046154,2.089059189581746,-0.029373324329508732,-0.7334476908882873,-0.5182986952552782,0.4348513834489541,-0.9331880544660163,0.33752223620233285,-0.2899790727297725,4.115215060881295,-0.11471723023422291,-0.42567786323215334,1.3183566065504058,1.414993690331867,-1.1684895504192612,-0.22351964620585527,-0.09324252520289562,0.03368205509537154,-0.9587584321347755,1.3183566065504058,1.525559168791652,0.5492309315430891,0.23827674360495169,0.0545236662877855,-0.6366330002875932,0.11652951958878897,-0.8572966837718823,1.2033338913699734,0.3178291459077337,1.2693680383752384,-0.008265595708049227,-0.22351964620585527,1.186695066202737,0.8777721115317447,-0.4717666193892306,-0.6127320061884703,1.509903867033398,0.661098451902834,0.5680465845888625,-0.09324252520289562,0.8065551874323789,-1.4732257420217356,-2.832999263059134,-0.17970910315454527,-0.75796101573055,-0.3800230309908234,-0.008265595708049227,-0.05057146887282142,-0.5652838070018109,0.661098451902834,-1.088736557366239,-0.6847954503580282,0.03368205509537154,0.7705748236465301,1.3020775180976913,-0.3573554842529024,-0.2899790727297725,2.7894153625147196,1.649178704645811,4.164468347330218,-0.3573554842529024,0.2782103405843624,1.7250193216134055,1.000093579058044,-0.5652838070018109,1.6796433852720836,0.29805874290970236,-0.9587584321347755,0.13702781813267018,0.0545236662877855,1.153258456656166,0.35713869105956414,-0.22351964620585527,0.661098451902834,-0.9587584321347755,-0.17970910315454527,0.7705748236465301,-0.8073693656405042,0.3766791785599655,2.214391369466817,1.000093579058044 | 3,040 |
Myoclonus | 18 | 89 | 2.657652 | 0.007869 | P00374,P00846,Q01105,P05067,Q96CU9,Q10713,Q9NQZ5,Q9NZJ7,P07602,P04062,Q14108,Q96N67,P03886,P50897,Q9UBX3,O75503,P21281,Q9Y4G8 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 5,6,354,74,75,250,144,345,244,243,52,412,54,120,451,91,286,31 | 1586,2176,2437,1213,600,765,91,2407,2538,1737,1189,5,436,6,54,243,2074,74,244,2539,973,1891,1894,286,2339,769,1520,2341,2042,1523,1059,1293,2798,1968,2084,120,2621,1899,1483,1937,609,1570,1864,354,1262,1157,2550,250,1629,1866,1038,52,1975,2515,1909,2161,1912,1914,1138,2279,1171,2972,2281,1271,75,756,1716,1391,2727,412,529,2942,899,2282,1355,1719,1314,1539,2255,144,1430,1580,2287,345,451,2832,31,2295,2589 | -0.13628593823390364,-0.49497664277843795,-0.6847954503580282,0.07527824008221333,0.5867930584046154,0.4348513834489541,2.1590406610189636,-0.6606536956722414,-0.75796101573055,-0.22351964620585527,0.09594659045201429,4.300267789916809,0.7885964023248992,4.290668707384786,2.739511278775411,1.3183566065504058,-0.42567786323215334,2.2963894486711554,1.3183566065504058,-0.75796101573055,0.23827674360495169,-0.312334586919792,-0.312334586919792,1.186695066202737,-0.6127320061884703,0.4348513834489541,-0.09324252520289562,-0.6127320061884703,-0.4027967817372936,-0.09324252520289562,0.1777736295870345,0.03368205509537154,-1.062451521523199,-0.3573554842529024,-0.42567786323215334,1.960793573015321,-0.8322673872621336,-0.312334586919792,-0.07186090588440568,-0.334793033079157,0.5867930584046154,-0.11471723023422291,-0.2899790727297725,0.965437543137018,0.0545236662877855,0.11652951958878897,-0.75796101573055,1.3020775180976913,-0.1579495805967917,-0.2899790727297725,0.19802266801457014,2.7894153625147196,-0.3573554842529024,-0.7334476908882873,-0.312334586919792,-0.4717666193892306,-0.312334586919792,-0.312334586919792,0.13702781813267018,-0.5652838070018109,0.11652951958878897,-1.7082855307060512,-0.5652838070018109,0.0545236662877855,2.2963894486711554,0.45409450442527205,-0.2015654664810097,-0.008265595708049227,-0.9587584321347755,0.8422863325591908,0.6795074351426921,-1.5019546528638092,0.3178291459077337,-0.5652838070018109,0.012752580513801317,-0.2015654664810097,0.03368205509537154,-0.09324252520289562,-0.5417340014635557,1.8294352882830525,-0.029373324329508732,-0.11471723023422291,-0.5652838070018109,1.000093579058044,0.7885964023248992,-1.1151699685618548,3.208350910072947,-0.5652838070018109,-0.7826010790948131 | 3,040 |
Contractures of the joints of the upper limbs | 24 | 69 | 2.648634 | 0.008082 | Q9NR77,Q15392,P16435,P23786,P35637,Q9NPF4,O43909,Q99567,P27635,Q9H4L7,P37268,O75844,P42892,Q99720,Q96L58,O75530,Q7LGA3,P07196,Q96AY3,Q8IZA0,P57740,Q9BUB7,O75419,Q9Y619 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 2,7,285,32,535,562,422,306,553,310,53,58,67,69,327,215,222,604,359,104,607,639,498,125 | 1547,2362,1322,624,422,1324,2998,1326,498,215,58,2301,1820,2073,738,604,285,974,2939,2834,32,553,1402,2693,535,53,933,67,2913,2765,2547,1086,2621,1525,607,2986,2271,1830,1197,2515,1700,793,1228,7,1835,1015,880,222,104,1498,1600,2053,1601,359,327,2580,306,69,1353,639,2427,310,562,2,1582,1025,970,125,2435 | -0.11471723023422291,-0.6366330002875932,0.012752580513801317,0.5680465845888625,0.8065551874323789,0.012752580513801317,-2.052859180393565,0.012752580513801317,0.7161283312130348,1.3990093317163634,2.676504066166205,-0.5889493789129632,-0.26772543458963366,-0.42567786323215334,0.45409450442527205,0.5867930584046154,1.186695066202737,0.23827674360495169,-1.5019546528638092,-1.141753653942985,3.196797074340647,0.6426230676699337,-0.029373324329508732,-0.907755404541169,0.661098451902834,2.776980594626845,0.2782103405843624,2.4436369051693405,-1.3881021776971274,-1.0103191649269512,-0.75796101573055,0.1574422653969169,-0.8322673872621336,-0.09324252520289562,0.5867930584046154,-1.8616370106422162,-0.5652838070018109,-0.26772543458963366,0.09594659045201429,-0.7334476908882873,-0.2015654664810097,0.4155348788904062,0.07527824008221333,4.164468347330218,-0.26772543458963366,0.21819012730572218,0.33752223620233285,1.3829766872888838,2.074955115714817,-0.07186090588440568,-0.13628593823390364,-0.4027967817372936,-0.13628593823390364,0.965437543137018,1.0345204898018696,-0.7826010790948131,1.1027003870412346,2.390543045095957,0.012752580513801317,0.5680465845888625,-0.6606536956722414,1.0857386233802766,0.6426230676699337,4.599675697788404,-0.11471723023422291,0.21819012730572218,0.25828324277369913,1.946353972838871,-0.6606536956722414 | 3,040 |
Coated vesicle | 24 | 91 | 2.644423 | 0.008183 | P24390,Q5VW38,P53680,O95070,Q96RQ1,Q9P253,Q15363,Q14108,Q99523,Q9Y5U9,O00165,P11717,P10321,P42892,P05067,O43752,Q9Y282,Q9Y678,P02786,O14579,Q13190,P20645,Q8N511,Q9Y3B3 | Localization | GO Cellular component | msigdb_gocc | 1,24,417,414,301,302,443,52,183,326,191,438,437,67,74,78,81,208,219,466,220,99,105,384 | 191,1609,1547,466,2069,2437,1029,1784,550,1113,78,2819,1928,2503,2637,1888,2439,414,2072,1373,1554,219,552,74,1375,2598,437,2948,2075,438,2912,99,1,808,67,1694,935,977,1863,1221,1258,1752,1482,2154,1035,417,1445,630,2379,1662,2312,1664,1864,2986,1008,501,220,1632,52,2193,443,2158,24,1635,105,2972,1272,756,301,183,2609,984,2231,985,859,2967,302,2831,2499,1360,2288,839,952,81,1815,384,326,994,208,1467,2068 | 1.525559168791652,-0.1579495805967917,-0.11471723023422291,0.7524899549765799,-0.42567786323215334,-0.6847954503580282,0.19802266801457014,-0.2455726333366303,0.6426230676699337,0.13702781813267018,2.269191783909705,-1.1151699685618548,-0.334793033079157,-0.7334476908882873,-0.8572966837718823,-0.312334586919792,-0.6847954503580282,0.8244516693582026,-0.42567786323215334,-0.008265595708049227,-0.11471723023422291,1.3829766872888838,0.6426230676699337,2.2963894486711554,-0.008265595708049227,-0.8073693656405042,0.7885964023248992,-1.5599592297881615,-0.42567786323215334,0.7885964023248992,-1.3881021776971274,2.089059189581746,4.599675697788404,0.39614435776678325,2.4436369051693405,-0.2015654664810097,0.2782103405843624,0.23827674360495169,-0.2899790727297725,0.07527824008221333,0.0545236662877855,-0.22351964620585527,-0.07186090588440568,-0.4717666193892306,0.19802266801457014,0.8244516693582026,-0.05057146887282142,0.5680465845888625,-0.6366330002875932,-0.17970910315454527,-0.5889493789129632,-0.17970910315454527,-0.2899790727297725,-1.8616370106422162,0.21819012730572218,0.7161283312130348,1.3829766872888838,-0.1579495805967917,2.7894153625147196,-0.49497664277843795,0.7885964023248992,-0.4717666193892306,3.4013110206392003,-0.1579495805967917,2.0608146287550606,-1.7082855307060512,0.0545236662877855,0.45409450442527205,1.1196073499123598,1.5877256647712878,-0.8073693656405042,0.23827674360495169,-0.5182986952552782,0.23827674360495169,0.35713869105956414,-1.6483728475080308,1.1196073499123598,-1.1151699685618548,-0.7090596464820835,0.012752580513801317,-0.5652838070018109,0.3766791785599655,0.2782103405843624,2.2555425979007304,-0.2455726333366303,0.8954241674177924,1.0516490831696563,0.23827674360495169,1.4468188512391555,-0.05057146887282142,-0.4027967817372936 | 3,040 |
Glycerophospholipid metabolism | 6 | 18 | 2.644261 | 0.008187 | Q9HBU6,Q9UG56,Q8NCC3,Q6P1A2,P35790,Q96N66 | Processes and pathways | KEGG Pathways | msigdb_kegg | 34,164,17,151,92,224 | 517,2504,2663,1738,92,934,2765,151,300,1268,17,1773,2052,224,1274,34,1579,164 | 0.6795074351426921,-0.7334476908882873,-0.8824588236038856,-0.22351964620585527,2.145115533980319,0.2782103405843624,-1.0103191649269512,1.7849324461832374,1.1196073499123598,0.0545236662877855,3.748046944176162,-0.22351964620585527,-0.4027967817372936,1.3829766872888838,0.0545236662877855,3.1503484036762917,-0.11471723023422291,1.7250193216134055 | 3,040 |
Threonine type peptidase activity | 7 | 10 | 2.643783 | 0.008199 | P28070,P49721,Q9UJ14,P28072,P49720,P28074,P20618 | Functions | GO Molecular function | msigdb_gomf | 193,142,180,277,278,312,154 | 154,1083,193,277,312,278,142,2093,420,180 | 1.7550590252104994,0.1574422653969169,1.509903867033398,1.2033338913699734,1.0687216574483722,1.2033338913699734,1.8294352882830525,-0.42567786323215334,0.8244516693582026,1.6031550889336454 | 3,040 |
Phosphatidylcholine metabolic process | 6 | 16 | 2.642893 | 0.00822 | Q9NP80,Q8WTV0,Q8NCC3,Q6P1A2,P35790,Q96N66 | Processes and pathways | GO Biological process | msigdb_gobp | 163,41,17,151,92,224 | 886,1738,2078,92,2621,2853,1707,151,300,1268,2051,17,1773,41,224,163 | 0.3178291459077337,-0.22351964620585527,-0.42567786323215334,2.145115533980319,-0.8322673872621336,-1.1684895504192612,-0.2015654664810097,1.7849324461832374,1.1196073499123598,0.0545236662877855,-0.4027967817372936,3.748046944176162,-0.22351964620585527,3.032555550251405,1.3829766872888838,1.7250193216134055 | 3,040 |
Apical part of cell | 13 | 52 | 2.63556 | 0.0084 | O00165,P08183,P51790,P36551,P05067,P04083,P41440,Q99538,P53985,Q13277,Q99808,P21281,Q9Y4G8 | Localization | GO Cellular component | msigdb_gocc | 191,66,469,426,74,467,239,279,26,371,93,286,31 | 191,804,2069,2788,999,1030,1032,467,1476,74,66,1081,2370,2302,973,1892,1376,929,1654,286,2079,1084,483,976,2508,426,1059,1085,239,469,26,1564,1624,2155,2268,2248,371,1904,1411,2217,723,1132,1669,2774,279,1205,93,1677,2172,884,31,1106 | 1.525559168791652,0.39614435776678325,-0.42567786323215334,-1.062451521523199,0.21819012730572218,0.19802266801457014,0.19802266801457014,0.7524899549765799,-0.07186090588440568,2.2963894486711554,2.4831277053176017,0.1574422653969169,-0.6366330002875932,-0.5889493789129632,0.23827674360495169,-0.312334586919792,-0.008265595708049227,0.2782103405843624,-0.17970910315454527,1.186695066202737,-0.42567786323215334,0.1574422653969169,0.7343412937617894,0.23827674360495169,-0.7334476908882873,0.8065551874323789,0.1777736295870345,0.1574422653969169,1.3345857255664315,0.7524899549765799,3.3901366110400533,-0.11471723023422291,-0.1579495805967917,-0.4717666193892306,-0.5652838070018109,-0.5417340014635557,0.9130162849921596,-0.312334586919792,-0.029373324329508732,-0.5182986952552782,0.47326486642030946,0.13702781813267018,-0.17970910315454527,-1.0103191649269512,1.2033338913699734,0.09594659045201429,2.145115533980319,-0.17970910315454527,-0.4717666193892306,0.33752223620233285,3.208350910072947,0.1574422653969169 | 3,040 |
Abnormal nephron morphology | 17 | 64 | 2.630937 | 0.008515 | P23786,P00403,P00846,P00813,P06280,Q8N1F7,Q8NFH4,Q9NQH7,O43826,O75306,Q14C86,Q12769,Q14108,Q9NZ08,P03886,O95470,Q9Y4P3 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 32,436,6,8,297,430,267,106,396,108,364,380,52,84,54,405,421 | 1150,1957,1587,396,1286,108,586,1152,2538,405,436,8,6,1554,2073,54,297,2473,1651,2147,1377,2239,1963,2149,32,2341,1562,2794,2795,1657,1623,2154,607,1663,2415,2047,2986,1298,1262,2125,459,380,52,364,2219,2552,1668,2928,2518,430,267,1498,854,1272,2282,706,562,106,2910,84,1464,2065,2534,421 | 0.11652951958878897,-0.3573554842529024,-0.13628593823390364,0.8600596556567248,0.03368205509537154,2.046637516393822,0.6054709229335996,0.11652951958878897,-0.75796101573055,0.8422863325591908,0.7885964023248992,4.115215060881295,4.290668707384786,-0.11471723023422291,-0.42567786323215334,2.739511278775411,1.1364599089502991,-0.7090596464820835,-0.17970910315454527,-0.4717666193892306,-0.008265595708049227,-0.5417340014635557,-0.3573554842529024,-0.4717666193892306,3.196797074340647,-0.6127320061884703,-0.11471723023422291,-1.062451521523199,-1.062451521523199,-0.17970910315454527,-0.1579495805967917,-0.4717666193892306,0.5867930584046154,-0.17970910315454527,-0.6606536956722414,-0.4027967817372936,-1.8616370106422162,0.03368205509537154,0.0545236662877855,-0.44866742092299217,0.7705748236465301,0.8954241674177924,2.7894153625147196,0.9305489204651839,-0.5182986952552782,-0.75796101573055,-0.17970910315454527,-1.444675674895682,-0.7334476908882873,0.8065551874323789,1.2529369403504902,-0.07186090588440568,0.35713869105956414,0.0545236662877855,-0.5652838070018109,0.4923630858030608,0.6426230676699337,2.0608146287550606,-1.3600739325016569,2.214391369466817,-0.05057146887282142,-0.4027967817372936,-0.7334476908882873,0.8244516693582026 | 3,040 |
Peptide binding | 8 | 66 | 2.625578 | 0.00865 | P24390,P42892,Q15392,Q9Y584,Q8WTV0,P55786,Q9NZ08,Q9UHB9 | Functions | GO Molecular function | msigdb_gomf | 1,67,7,72,41,47,84,21 | 995,584,1367,1213,1648,2366,550,1514,1251,1554,552,2302,1375,2598,437,1329,699,2375,1,2340,2763,2478,1824,2042,2264,348,67,1693,2932,2601,1592,1086,936,2045,719,47,2183,1663,774,1664,1007,2550,2697,1632,1868,2940,502,7,1672,41,382,2055,756,1603,1098,2752,360,2168,707,3013,84,21,465,97,2500,72 | 0.21819012730572218,0.6054709229335996,-0.008265595708049227,0.07527824008221333,-0.17970910315454527,-0.6366330002875932,0.6426230676699337,-0.09324252520289562,0.0545236662877855,-0.11471723023422291,0.6426230676699337,-0.5889493789129632,-0.008265595708049227,-0.8073693656405042,0.7885964023248992,0.012752580513801317,0.4923630858030608,-0.6366330002875932,4.599675697788404,-0.6127320061884703,-1.0103191649269512,-0.7090596464820835,-0.26772543458963366,-0.4027967817372936,-0.5652838070018109,0.982794416200427,2.4436369051693405,-0.2015654664810097,-1.4732257420217356,-0.8073693656405042,-0.13628593823390364,0.1574422653969169,0.2782103405843624,-0.4027967817372936,0.47326486642030946,2.8879227390379008,-0.49497664277843795,-0.17970910315454527,0.4348513834489541,-0.17970910315454527,0.21819012730572218,-0.75796101573055,-0.907755404541169,-0.1579495805967917,-0.2899790727297725,-1.5019546528638092,0.7161283312130348,4.164468347330218,-0.17970910315454527,3.032555550251405,0.8954241674177924,-0.4027967817372936,0.45409450442527205,-0.13628593823390364,0.1574422653969169,-0.9844682279779907,0.965437543137018,-0.4717666193892306,0.4923630858030608,-2.2868934207788545,2.214391369466817,3.566403837715786,0.7705748236465301,2.1031270607559645,-0.7090596464820835,2.350387100739699 | 3,040 |
Glycosylation | 17 | 45 | 2.625129 | 0.008662 | O15118,Q96L58,Q9BXS4,Q9H9E3,Q9BV10,Q86YN1,Q10472,Q14165,Q9HC07,O43909,P46977,O60502,P04062,O60476,O43505,O75503,Q9Y5P6 | Processes and pathways | GO Biological process | msigdb_gobp | 98,327,198,464,138,43,363,489,175,422,520,50,243,403,185,91,317 | 2362,98,1186,185,422,403,50,2998,1399,2503,91,2538,243,1080,2261,1893,1896,520,2345,2271,612,1008,792,363,2349,489,1417,1419,1138,43,797,327,545,138,983,198,1675,1102,464,1540,175,2681,2684,710,317 | -0.6366330002875932,2.089059189581746,0.09594659045201429,1.5567327633064831,0.8065551874323789,0.8422863325591908,2.8511827392039613,-2.052859180393565,-0.029373324329508732,-0.7334476908882873,2.1590406610189636,-0.75796101573055,1.3183566065504058,0.1574422653969169,-0.5652838070018109,-0.312334586919792,-0.312334586919792,0.6795074351426921,-0.6127320061884703,-0.5652838070018109,0.5867930584046154,0.21819012730572218,0.4155348788904062,0.9480225246677504,-0.6127320061884703,0.7343412937617894,-0.029373324329508732,-0.029373324329508732,0.13702781813267018,2.9727372035954707,0.4155348788904062,1.0345204898018696,0.661098451902834,1.8735753952262877,0.23827674360495169,1.4942024923485768,-0.17970910315454527,0.1574422653969169,0.7705748236465301,-0.09324252520289562,1.649178704645811,-0.8824588236038856,-0.8824588236038856,0.4923630858030608,1.0687216574483722 | 3,040 |
Cation transport | 27 | 144 | 2.625094 | 0.008663 | P78417,P00846,P62942,P21796,O15173,O00400,P21281,Q70HW3,Q9HD20,O43772,Q9HC07,Q9HD47,Q13555,O75844,Q13423,P05067,P24941,Q99808,P02786,Q9UDW1,Q96GC9,Q8IYU8,Q9P246,O75964,Q9H4I9,Q7KZN9,Q9Y619 | Processes and pathways | GO Biological process | msigdb_gobp | 130,6,11,12,394,20,286,33,40,44,175,176,309,58,60,74,212,93,219,234,374,372,248,378,252,381,125 | 2536,20,693,1586,2590,600,394,1150,44,1370,1030,2299,2036,957,2662,2143,1551,58,2003,378,1886,2881,1684,436,6,219,1117,1476,74,1288,2689,1741,2441,1961,1518,1081,2237,806,2822,1252,1153,867,1891,958,519,2938,1616,1654,1558,286,2079,2939,12,1860,212,2762,406,1786,2763,2545,1123,1291,483,2896,871,2508,1059,1293,2620,1480,2954,1863,469,1752,1564,1624,571,2643,608,2268,1222,1663,1449,11,130,790,1092,811,1864,775,662,878,2188,2550,2966,60,309,2891,1197,1764,2454,1833,1012,2518,33,381,594,372,1772,504,2813,2607,557,374,1173,1576,2888,2775,93,2229,832,1504,1675,2611,1721,252,1539,2233,175,708,40,176,248,234,710,1509,2585,2787,1363,2291,1182,1584,2295,125 | -0.75796101573055,3.5772458059331473,0.4923630858030608,-0.13628593823390364,-0.8073693656405042,0.5867930584046154,0.8600596556567248,0.11652951958878897,2.9606979194992413,-0.008265595708049227,0.19802266801457014,-0.5889493789129632,-0.4027967817372936,0.25828324277369913,-0.8824588236038856,-0.4717666193892306,-0.11471723023422291,2.676504066166205,-0.3800230309908234,0.8954241674177924,-0.312334586919792,-1.24963046884146,-0.2015654664810097,0.7885964023248992,4.290668707384786,1.3829766872888838,0.13702781813267018,-0.07186090588440568,2.2963894486711554,0.03368205509537154,-0.907755404541169,-0.22351964620585527,-0.6847954503580282,-0.3573554842529024,-0.09324252520289562,0.1574422653969169,-0.5417340014635557,0.39614435776678325,-1.1151699685618548,0.0545236662877855,0.11652951958878897,0.33752223620233285,-0.312334586919792,0.25828324277369913,0.6795074351426921,-1.5019546528638092,-0.1579495805967917,-0.17970910315454527,-0.11471723023422291,1.186695066202737,-0.42567786323215334,-1.5019546528638092,3.8419900405287315,-0.2899790727297725,1.414993690331867,-1.0103191649269512,0.8422863325591908,-0.2455726333366303,-1.0103191649269512,-0.75796101573055,0.13702781813267018,0.03368205509537154,0.7343412937617894,-1.3045227910643165,0.33752223620233285,-0.7334476908882873,0.1777736295870345,0.03368205509537154,-0.8322673872621336,-0.07186090588440568,-1.589240151276104,-0.2899790727297725,0.7524899549765799,-0.22351964620585527,-0.11471723023422291,-0.1579495805967917,0.624080740847125,-0.8572966837718823,0.5867930584046154,-0.5652838070018109,0.07527824008221333,-0.17970910315454527,-0.05057146887282142,3.8626651909366387,1.9028038748611003,0.4155348788904062,0.1574422653969169,0.39614435776678325,-0.2899790727297725,0.4348513834489541,0.5303455219239778,0.33752223620233285,-0.49497664277843795,-0.75796101573055,-1.6483728475080308,2.6127834871538127,1.0857386233802766,-1.2769953776362524,0.09594659045201429,-0.22351964620585527,-0.6847954503580282,-0.26772543458963366,0.21819012730572218,-0.7334476908882873,3.1619957827526095,0.8954241674177924,0.6054709229335996,0.9130162849921596,-0.22351964620585527,0.7161283312130348,-1.088736557366239,-0.8073693656405042,0.6426230676699337,0.9130162849921596,0.11652951958878897,-0.11471723023422291,-1.24963046884146,-1.0103191649269512,2.145115533980319,-0.5182986952552782,0.3766791785599655,-0.07186090588440568,-0.17970910315454527,-0.8073693656405042,-0.2015654664810097,1.3020775180976913,-0.09324252520289562,-0.5182986952552782,1.649178704645811,0.4923630858030608,3.0444444324111646,1.649178704645811,1.3183566065504058,1.366895427454461,0.4923630858030608,-0.07186090588440568,-0.7826010790948131,-1.0363129992676252,0.012752580513801317,-0.5652838070018109,0.11652951958878897,-0.11471723023422291,-0.5652838070018109,1.946353972838871 | 3,040 |
Gpcr ligand binding | 6 | 10 | 2.624003 | 0.00869 | P42892,Q9BYT8,Q9NRV9,P05067,Q9NZJ7,P07602 | Processes and pathways | Reactome Pathways | msigdb_reactome | 67,360,200,74,345,244 | 467,74,244,67,1223,360,200,345,1245,1025 | 0.7524899549765799,2.2963894486711554,1.3183566065504058,2.4436369051693405,0.07527824008221333,0.965437543137018,1.4942024923485768,1.000093579058044,0.07527824008221333,0.21819012730572218 | 3,040 |
Monooxygenase activity | 6 | 8 | 2.623636 | 0.0087 | Q6UW02,P30519,Q16850,Q15800,Q9BU89,P09601 | Functions | GO Molecular function | msigdb_gomf | 294,70,18,179,187,284 | 284,70,743,319,179,18,294,187 | 1.186695066202737,2.377189975700653,0.45409450442527205,1.0516490831696563,1.6185402139192084,3.631156676050709,1.153258456656166,1.5567327633064831 | 3,040 |
Cross presentation of soluble exogenous antigens endosomes | 11 | 37 | 2.609293 | 0.009073 | Q92530,P28070,P61289,P49721,Q9UL46,Q9UBG0,P28072,P49720,P60900,P28074,P20618 | Processes and pathways | Reactome Pathways | msigdb_reactome | 322,193,293,142,238,213,277,278,85,312,154 | 642,2564,1470,2807,998,1188,2178,154,2445,2007,1082,1083,1823,193,277,312,2720,1897,1790,278,142,1444,1593,85,293,1335,1900,2346,776,1865,1340,322,420,2103,213,238,1583 | 0.5492309315430891,-0.7826010790948131,-0.07186090588440568,-1.088736557366239,0.21819012730572218,0.09594659045201429,-0.49497664277843795,1.7550590252104994,-0.6847954503580282,-0.3800230309908234,0.1574422653969169,0.1574422653969169,-0.26772543458963366,1.509903867033398,1.2033338913699734,1.0687216574483722,-0.9587584321347755,-0.312334586919792,-0.2455726333366303,1.2033338913699734,1.8294352882830525,-0.05057146887282142,-0.13628593823390364,2.2006057669567936,1.153258456656166,0.012752580513801317,-0.312334586919792,-0.6127320061884703,0.4348513834489541,-0.2899790727297725,0.012752580513801317,1.0516490831696563,0.8244516693582026,-0.42567786323215334,1.414993690331867,1.3507652191046324,-0.11471723023422291 | 3,040 |
Liposaccharide metabolic process | 9 | 17 | 2.597064 | 0.009402 | P06865,Q8NBX0,P06280,P16278,Q05655,P04062,Q5H8A4,P04066,Q92643 | Processes and pathways | GO Biological process | msigdb_gobp | 291,9,297,258,459,243,503,211,223 | 1549,1399,243,211,297,291,2408,258,2307,459,503,9,223,897,1043,618,1208 | -0.11471723023422291,-0.029373324329508732,1.3183566065504058,1.414993690331867,1.1364599089502991,1.153258456656166,-0.6606536956722414,1.2693680383752384,-0.5889493789129632,0.7705748236465301,0.7161283312130348,3.9751084735818023,1.3829766872888838,0.3178291459077337,0.19802266801457014,0.5867930584046154,0.09594659045201429 | 3,040 |
Hydrolase activity hydrolyzing o glycosyl compounds | 11 | 21 | 2.583584 | 0.009778 | P08236,Q86W56,Q9NUJ1,P16278,P06865,P06280,O60502,P04062,P04066,Q9BTY2,O60476 | Functions | GO Molecular function | msigdb_gomf | 192,538,39,258,291,297,50,243,211,447,403 | 713,1368,403,50,243,211,297,291,2408,192,646,258,2307,1788,536,2125,2349,2218,538,447,39 | 0.47326486642030946,-0.008265595708049227,0.8422863325591908,2.8511827392039613,1.3183566065504058,1.414993690331867,1.1364599089502991,1.153258456656166,-0.6606536956722414,1.525559168791652,0.5492309315430891,1.2693680383752384,-0.5889493789129632,-0.2455726333366303,0.661098451902834,-0.44866742092299217,-0.6127320061884703,-0.5182986952552782,0.661098451902834,0.7885964023248992,3.0799635941056946 | 3,040 |
Metalloprotease | 13 | 39 | 2.58095 | 0.009853 | P02786,Q9UIQ6,P42892,O75844,O43847,P22695,P55786,Q9NZ08,P52888,Q96E52,Q10713,Q5JRX3,Q7Z2K6 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 219,97,67,58,330,268,47,84,338,157,250,349,155 | 1956,1470,841,330,1551,58,1737,219,2148,2639,1329,268,3003,1123,67,1444,338,509,47,250,2157,1703,349,666,155,2749,2252,730,2946,157,2803,2493,1205,2859,360,2173,84,97,2295 | -0.3573554842529024,-0.07186090588440568,0.35713869105956414,1.0173354618632569,-0.11471723023422291,2.676504066166205,-0.22351964620585527,1.3829766872888838,-0.4717666193892306,-0.8572966837718823,0.012752580513801317,1.2364544592660984,-2.1184700311575546,0.13702781813267018,2.4436369051693405,-0.05057146887282142,1.000093579058044,0.6978505521998537,2.8879227390379008,1.3020775180976913,-0.4717666193892306,-0.2015654664810097,0.982794416200427,0.5303455219239778,1.7550590252104994,-0.9844682279779907,-0.5417340014635557,0.47326486642030946,-1.5308649492817303,1.7550590252104994,-1.062451521523199,-0.7090596464820835,0.09594659045201429,-1.1684895504192612,0.965437543137018,-0.4717666193892306,2.214391369466817,2.1031270607559645,-0.5652838070018109 | 3,040 |
Organophosphate ester transport | 15 | 28 | 2.574637 | 0.010035 | P08183,P22059,Q8WTV0,Q9BSK2,Q05655,Q9H2D1,O43826,P41440,O00400,Q14108,Q96GC9,Q9HC21,Q99808,Q8NB49,Q8TB61 | Processes and pathways | GO Biological process | msigdb_gobp | 66,570,41,171,459,46,396,239,20,52,374,708,93,704,540 | 20,1370,396,1288,66,867,698,570,2150,239,909,2448,459,1628,52,1836,3027,704,540,798,41,374,93,171,1878,46,708,2431 | 3.5772458059331473,-0.008265595708049227,0.8600596556567248,0.03368205509537154,2.4831277053176017,0.33752223620233285,0.4923630858030608,0.624080740847125,-0.4717666193892306,1.3345857255664315,0.29805874290970236,-0.6847954503580282,0.7705748236465301,-0.1579495805967917,2.7894153625147196,-0.26772543458963366,-2.832999263059134,0.4923630858030608,0.661098451902834,0.4155348788904062,3.032555550251405,0.9130162849921596,2.145115533980319,1.6644326324480352,-0.2899790727297725,2.900116777063521,0.4923630858030608,-0.6606536956722414 | 3,040 |
Arthritis | 13 | 38 | 2.573455 | 0.010069 | P10321,P28070,Q96HY6,P21964,P06280,Q9NUQ7,O43826,Q14739,P04062,P14174,Q14108,Q9NZ08,O75844 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 437,193,296,387,297,205,396,173,243,276,52,84,58 | 1433,396,2703,58,1516,1554,2073,243,297,2370,437,2760,276,387,2834,193,1657,2548,1379,2154,1445,1483,1663,2986,459,1866,52,173,1700,852,919,296,1777,1102,205,84,1952,549 | -0.05057146887282142,0.8600596556567248,-0.9331880544660163,2.676504066166205,-0.09324252520289562,-0.11471723023422291,-0.42567786323215334,1.3183566065504058,1.1364599089502991,-0.6366330002875932,0.7885964023248992,-1.0103191649269512,1.2033338913699734,0.8777721115317447,-1.141753653942985,1.509903867033398,-0.17970910315454527,-0.75796101573055,-0.008265595708049227,-0.4717666193892306,-0.05057146887282142,-0.07186090588440568,-0.17970910315454527,-1.8616370106422162,0.7705748236465301,-0.2899790727297725,2.7894153625147196,1.649178704645811,-0.2015654664810097,0.35713869105956414,0.29805874290970236,1.153258456656166,-0.22351964620585527,0.1574422653969169,1.462660295599955,2.214391369466817,-0.334793033079157,0.661098451902834 | 3,040 |
Adaptive immune system | 39 | 176 | 2.572892 | 0.010085 | Q9UJW0,P19474,P62942,P49721,P30260,P28072,P49720,Q99538,P20618,Q99436,P53680,O94822,P61289,P60604,P30153,O94874,P55786,O75935,P28074,Q9UBS8,P10321,P28070,Q92530,P30154,P04350,Q9UBG0,Q9NZ08,P60900,P52888,Q7Z7E8,Q5KU26,Q9UJX3,Q9UIQ6,P10619,Q9UL46,P68371,Q9Y4B6,P49427,Q9BUF5 | Processes and pathways | Reactome Pathways | msigdb_reactome | 133,259,11,142,147,277,278,279,154,420,417,166,293,427,299,423,47,304,312,64,437,193,322,202,332,213,84,85,338,473,350,352,97,103,238,488,376,119,514 | 2140,1681,2536,2686,642,2564,1470,2807,996,2788,694,2438,998,1113,1030,2637,1188,304,166,423,1888,2439,1612,1613,1889,2072,1373,1554,332,552,2689,1001,1556,1375,437,103,2178,1616,259,154,2834,2445,2007,1082,1083,2340,1479,1823,193,277,312,626,2868,299,202,147,508,1692,1291,2720,2182,873,1897,1442,1563,1790,119,278,142,2799,1863,1333,1258,1444,2742,338,1481,1035,417,1445,1593,47,2213,427,85,2155,2184,2122,2695,772,293,1663,1335,1900,2346,11,1260,1569,1664,1665,849,744,1089,488,1864,2187,1007,1409,776,1940,2550,1526,2216,1865,2191,2626,537,2088,1226,2651,2709,1412,1413,1975,1010,1062,1700,1340,2453,1978,2158,1416,350,1634,2221,1040,2392,473,2711,1806,322,1270,650,756,2523,855,1576,420,2103,279,2676,514,1074,984,901,1355,2465,1781,1538,84,1209,213,64,97,133,838,352,951,238,1543,819,1583,1728,376,1467,2469 | -0.4717666193892306,-0.2015654664810097,-0.75796101573055,-0.907755404541169,0.5492309315430891,-0.7826010790948131,-0.07186090588440568,-1.088736557366239,0.21819012730572218,-1.062451521523199,0.4923630858030608,-0.6847954503580282,0.21819012730572218,0.13702781813267018,0.19802266801457014,-0.8572966837718823,0.09594659045201429,1.1027003870412346,1.694811237237262,0.8065551874323789,-0.312334586919792,-0.6847954503580282,-0.1579495805967917,-0.1579495805967917,-0.312334586919792,-0.42567786323215334,-0.008265595708049227,-0.11471723023422291,1.0173354618632569,0.6426230676699337,-0.907755404541169,0.21819012730572218,-0.11471723023422291,-0.008265595708049227,0.7885964023248992,2.074955115714817,-0.49497664277843795,-0.1579495805967917,1.2693680383752384,1.7550590252104994,-1.141753653942985,-0.6847954503580282,-0.3800230309908234,0.1574422653969169,0.1574422653969169,-0.6127320061884703,-0.07186090588440568,-0.26772543458963366,1.509903867033398,1.2033338913699734,1.0687216574483722,0.5680465845888625,-1.195379634020793,1.1196073499123598,1.462660295599955,1.799807445284277,0.6978505521998537,-0.2015654664810097,0.03368205509537154,-0.9587584321347755,-0.49497664277843795,0.33752223620233285,-0.312334586919792,-0.05057146887282142,-0.11471723023422291,-0.2455726333366303,1.960793573015321,1.2033338913699734,1.8294352882830525,-1.062451521523199,-0.2899790727297725,0.012752580513801317,0.0545236662877855,-0.05057146887282142,-0.9844682279779907,1.000093579058044,-0.07186090588440568,0.19802266801457014,0.8244516693582026,-0.05057146887282142,-0.13628593823390364,2.8879227390379008,-0.5182986952552782,0.8065551874323789,2.2006057669567936,-0.4717666193892306,-0.49497664277843795,-0.44866742092299217,-0.907755404541169,0.4348513834489541,1.153258456656166,-0.17970910315454527,0.012752580513801317,-0.312334586919792,-0.6127320061884703,3.8626651909366387,0.0545236662877855,-0.11471723023422291,-0.17970910315454527,-0.17970910315454527,0.35713869105956414,0.45409450442527205,0.1574422653969169,0.7343412937617894,-0.2899790727297725,-0.49497664277843795,0.21819012730572218,-0.029373324329508732,0.4348513834489541,-0.334793033079157,-0.75796101573055,-0.09324252520289562,-0.5182986952552782,-0.2899790727297725,-0.49497664277843795,-0.8322673872621336,0.661098451902834,-0.42567786323215334,0.07527824008221333,-0.8572966837718823,-0.9331880544660163,-0.029373324329508732,-0.029373324329508732,-0.3573554842529024,0.21819012730572218,0.1777736295870345,-0.2015654664810097,0.012752580513801317,-0.6847954503580282,-0.3573554842529024,-0.4717666193892306,-0.029373324329508732,0.982794416200427,-0.1579495805967917,-0.5182986952552782,0.19802266801457014,-0.6366330002875932,0.7524899549765799,-0.9331880544660163,-0.2455726333366303,1.0516490831696563,0.0545236662877855,0.5492309315430891,0.45409450442527205,-0.7334476908882873,0.35713869105956414,-0.11471723023422291,0.8244516693582026,-0.42567786323215334,1.2033338913699734,-0.8824588236038856,0.6978505521998537,0.1777736295870345,0.23827674360495169,0.3178291459077337,0.012752580513801317,-0.6847954503580282,-0.22351964620585527,-0.09324252520289562,2.214391369466817,0.09594659045201429,1.414993690331867,2.548331098748904,2.1031270607559645,1.8882093005118208,0.3766791785599655,0.982794416200427,0.2782103405843624,1.3507652191046324,-0.09324252520289562,0.39614435776678325,-0.11471723023422291,-0.2015654664810097,0.9130162849921596,-0.05057146887282142,-0.6847954503580282 | 3,040 |
Hydrocephalus | 21 | 71 | 2.571259 | 0.010133 | P21964,Q15392,O60826,P16435,P23786,O96028,O60566,Q86WC4,P30153,O43505,Q9Y5P6,P08236,O75312,Q08AM6,Q96L58,Q93009,P40855,Q15125,P35222,P04062,Q10713 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 387,7,386,285,32,161,287,168,299,185,317,192,435,460,327,474,348,491,483,243,250 | 1368,1322,185,843,287,386,435,2703,1151,2881,161,243,1740,2037,1932,192,846,973,1893,285,974,2939,2239,387,32,299,2693,483,2619,348,2765,1379,521,1445,1595,1596,1006,1973,1828,1299,460,777,250,1629,2515,1062,491,7,1869,1836,168,1095,1496,919,2628,474,1271,1272,327,670,858,2393,1208,1540,2713,2027,1049,2430,690,992,317 | -0.008265595708049227,0.012752580513801317,1.5567327633064831,0.35713869105956414,1.170003381143128,0.8777721115317447,0.7885964023248992,-0.9331880544660163,0.11652951958878897,-1.24963046884146,1.7250193216134055,1.3183566065504058,-0.22351964620585527,-0.4027967817372936,-0.334793033079157,1.525559168791652,0.35713869105956414,0.23827674360495169,-0.312334586919792,1.186695066202737,0.23827674360495169,-1.5019546528638092,-0.5417340014635557,0.8777721115317447,3.196797074340647,1.1196073499123598,-0.907755404541169,0.7343412937617894,-0.8322673872621336,0.982794416200427,-1.0103191649269512,-0.008265595708049227,0.6795074351426921,-0.05057146887282142,-0.13628593823390364,-0.13628593823390364,0.21819012730572218,-0.3573554842529024,-0.26772543458963366,0.03368205509537154,0.7705748236465301,0.4348513834489541,1.3020775180976913,-0.1579495805967917,-0.7334476908882873,0.1777736295870345,0.7343412937617894,4.164468347330218,-0.2899790727297725,-0.26772543458963366,1.6796433852720836,0.1574422653969169,-0.07186090588440568,0.29805874290970236,-0.8322673872621336,0.7524899549765799,0.0545236662877855,0.0545236662877855,1.0345204898018696,0.5303455219239778,0.35713869105956414,-0.6366330002875932,0.09594659045201429,-0.09324252520289562,-0.9331880544660163,-0.3800230309908234,0.19802266801457014,-0.6606536956722414,0.5113897708571208,0.23827674360495169,1.0687216574483722 | 3,040 |
Proteasome beta-type subunit, conserved site [IPR016050] | 6 | 8 | 2.568319 | 0.010219 | P28070,P49721,P28072,P49720,P28074,P20618 | Sequence | InterPro Conserved site | interpro_conserved_site | 193,142,277,278,312,154 | 154,1083,193,277,312,278,142,420 | 1.7550590252104994,0.1574422653969169,1.509903867033398,1.2033338913699734,1.0687216574483722,1.2033338913699734,1.8294352882830525,0.8244516693582026 | 3,040 |
Threonine type endopeptidase activity | 6 | 8 | 2.568319 | 0.010219 | P28070,P49721,P28072,P49720,P28074,P20618 | Functions | GO Molecular function | msigdb_gomf | 193,142,277,278,312,154 | 154,1083,193,277,312,278,142,420 | 1.7550590252104994,0.1574422653969169,1.509903867033398,1.2033338913699734,1.0687216574483722,1.2033338913699734,1.8294352882830525,0.8244516693582026 | 3,040 |
Endoplasmic reticulum golgi intermediate compartment | 15 | 51 | 2.565853 | 0.010292 | P24390,Q13190,O95070,P80303,Q8N511,Q02818,Q10472,Q96RQ1,O15260,O15258,Q9Y678,Q9Y282,Q96GC9,O15155,Q9Y3B3 | Localization | GO Cellular component | msigdb_gocc | 1,220,414,71,105,362,363,301,353,395,208,81,374,282,384 | 2437,282,395,353,1250,2637,414,2037,1556,1,2340,1824,935,977,2826,1258,1482,1035,2212,630,1566,71,362,1007,1008,363,501,220,1762,2782,443,941,1635,1201,105,2099,1141,1839,374,301,684,2609,1720,2684,2831,710,81,1815,384,208,2068 | -0.6847954503580282,1.186695066202737,0.8600596556567248,0.965437543137018,0.0545236662877855,-0.8572966837718823,0.8244516693582026,-0.4027967817372936,-0.11471723023422291,4.599675697788404,-0.6127320061884703,-0.26772543458963366,0.2782103405843624,0.23827674360495169,-1.1151699685618548,0.0545236662877855,-0.07186090588440568,0.19802266801457014,-0.5182986952552782,0.5680465845888625,-0.11471723023422291,2.350387100739699,0.9480225246677504,0.21819012730572218,0.21819012730572218,0.9480225246677504,0.7161283312130348,1.3829766872888838,-0.22351964620585527,-1.0363129992676252,0.7885964023248992,0.2782103405843624,-0.1579495805967917,0.09594659045201429,2.0608146287550606,-0.42567786323215334,0.13702781813267018,-0.26772543458963366,0.9130162849921596,1.1196073499123598,0.5113897708571208,-0.8073693656405042,-0.2015654664810097,-0.8824588236038856,-1.1151699685618548,0.4923630858030608,2.2555425979007304,-0.2455726333366303,0.8954241674177924,1.4468188512391555,-0.4027967817372936 | 3,040 |
Inorganic anion transmembrane transporter activity | 6 | 17 | 2.560213 | 0.010461 | Q9C0H2,P21796,Q9Y277,P45880,O43826,Q9UBX3 | Functions | GO Molecular function | msigdb_gomf | 169,12,206,14,396,451 | 2361,1112,396,1218,12,14,469,1379,1624,1298,1913,798,2656,169,451,206,1106 | -0.6366330002875932,0.13702781813267018,0.8600596556567248,0.07527824008221333,3.8419900405287315,3.810841292230224,0.7524899549765799,-0.008265595708049227,-0.1579495805967917,0.03368205509537154,-0.312334586919792,0.4155348788904062,-0.8572966837718823,1.6796433852720836,0.7885964023248992,1.462660295599955,0.1574422653969169 | 3,040 |
Apical plasma membrane | 10 | 39 | 2.548664 | 0.010814 | P08183,P36551,P04083,P41440,Q13277,P53985,Q9Y4G8,Q99808,P21281,O00165 | Localization | GO Cellular component | msigdb_gocc | 66,426,467,239,371,26,31,93,286,191 | 191,804,2788,1030,1032,467,1476,66,1081,2370,2302,973,1892,1376,929,1654,286,1084,976,2508,426,1059,239,469,26,1564,1624,2268,371,2217,1132,1669,2774,1205,93,1677,2172,884,31 | 1.525559168791652,0.39614435776678325,-1.062451521523199,0.19802266801457014,0.19802266801457014,0.7524899549765799,-0.07186090588440568,2.4831277053176017,0.1574422653969169,-0.6366330002875932,-0.5889493789129632,0.23827674360495169,-0.312334586919792,-0.008265595708049227,0.2782103405843624,-0.17970910315454527,1.186695066202737,0.1574422653969169,0.23827674360495169,-0.7334476908882873,0.8065551874323789,0.1777736295870345,1.3345857255664315,0.7524899549765799,3.3901366110400533,-0.11471723023422291,-0.1579495805967917,-0.5652838070018109,0.9130162849921596,-0.5182986952552782,0.13702781813267018,-0.17970910315454527,-1.0103191649269512,0.09594659045201429,2.145115533980319,-0.17970910315454527,-0.4717666193892306,0.33752223620233285,3.208350910072947 | 3,040 |
Orc1 removal from chromatin | 14 | 48 | 2.534606 | 0.011257 | P20618,Q92530,P28070,P61289,Q9UBD5,P49721,Q9UL46,P28072,P49720,P24941,P28074,P60900,Q9Y619,Q99436 | Processes and pathways | Reactome Pathways | msigdb_reactome | 154,322,193,293,400,142,238,277,278,212,312,85,125,420 | 642,2564,1470,2807,998,1188,2178,154,212,1618,2445,2007,1082,1083,1823,193,277,312,1522,1292,931,2720,1897,1790,278,142,740,1444,1593,85,293,1335,1900,2346,744,776,1865,2191,2088,490,1340,322,420,2103,400,238,1583,125 | 0.5492309315430891,-0.7826010790948131,-0.07186090588440568,-1.088736557366239,0.21819012730572218,0.09594659045201429,-0.49497664277843795,1.7550590252104994,1.414993690331867,-0.1579495805967917,-0.6847954503580282,-0.3800230309908234,0.1574422653969169,0.1574422653969169,-0.26772543458963366,1.509903867033398,1.2033338913699734,1.0687216574483722,-0.09324252520289562,0.03368205509537154,0.2782103405843624,-0.9587584321347755,-0.312334586919792,-0.2455726333366303,1.2033338913699734,1.8294352882830525,0.45409450442527205,-0.05057146887282142,-0.13628593823390364,2.2006057669567936,1.153258456656166,0.012752580513801317,-0.312334586919792,-0.6127320061884703,0.45409450442527205,0.4348513834489541,-0.2899790727297725,-0.49497664277843795,-0.42567786323215334,0.7343412937617894,0.012752580513801317,1.0516490831696563,0.8244516693582026,-0.42567786323215334,0.8600596556567248,1.3507652191046324,-0.11471723023422291,1.946353972838871 | 3,040 |
External side of plasma membrane | 7 | 19 | 2.534255 | 0.011269 | P02786,P08183,P42892,O96005,P00813,P41440,P04083 | Localization | GO Cellular component | msigdb_gocc | 219,66,67,257,8,239,467 | 1032,257,928,8,219,467,2689,2037,66,1400,1329,1893,2078,2340,239,67,1657,469,2220 | 0.19802266801457014,1.2693680383752384,0.2782103405843624,4.115215060881295,1.3829766872888838,0.7524899549765799,-0.907755404541169,-0.4027967817372936,2.4831277053176017,-0.029373324329508732,0.012752580513801317,-0.312334586919792,-0.42567786323215334,-0.6127320061884703,1.3345857255664315,2.4436369051693405,-0.17970910315454527,0.7524899549765799,-0.5182986952552782 | 3,040 |
Bulbar signs | 6 | 12 | 2.529331 | 0.011428 | Q99720,P00846,Q9Y263,P07602,P04062,P03886 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 69,6,139,244,243,54 | 1112,6,54,243,738,244,535,874,2675,69,345,139 | 0.13702781813267018,4.290668707384786,2.739511278775411,1.3183566065504058,0.45409450442527205,1.3183566065504058,0.661098451902834,0.33752223620233285,-0.8824588236038856,2.390543045095957,1.000093579058044,1.8589019195979646 | 3,040 |
Cholesterol metabolism with bloch and kandutschrussell pathways | 7 | 22 | 2.52529 | 0.01156 | Q15392,Q14739,Q16850,Q15800,P48449,P37268,P35610 | Processes and pathways | WikiPathways | msigdb_wp | 7,173,18,179,245,53,289 | 1548,1286,886,1328,887,1747,289,53,245,1657,2874,1800,319,173,491,2484,7,2978,179,18,2354,690 | -0.11471723023422291,0.03368205509537154,0.3178291459077337,0.012752580513801317,0.3178291459077337,-0.22351964620585527,1.170003381143128,2.776980594626845,1.3183566065504058,-0.17970910315454527,-1.2224259209783335,-0.2455726333366303,1.0516490831696563,1.649178704645811,0.7343412937617894,-0.7090596464820835,4.164468347330218,-1.7690017501469077,1.6185402139192084,3.631156676050709,-0.6127320061884703,0.5113897708571208 | 3,040 |
Aurka activation by tpx2 | 12 | 32 | 2.522671 | 0.011647 | Q13561,Q9H6D7,P30153,O43805,O95684,P04350,O75935,P68371,P53350,P07437,O14965,Q96CS2 | Processes and pathways | Reactome Pathways | msigdb_reactome | 537,199,299,42,172,332,304,488,145,518,432,383 | 432,42,1371,304,568,172,332,1000,518,2005,299,1085,1255,145,772,1937,1449,849,488,2626,537,2781,1413,1975,723,851,1199,1267,383,2229,199,1951 | 0.7885964023248992,3.020641895229821,-0.008265595708049227,1.1027003870412346,0.624080740847125,1.649178704645811,1.0173354618632569,0.21819012730572218,0.6795074351426921,-0.3800230309908234,1.1196073499123598,0.1574422653969169,0.0545236662877855,1.8146416422908467,0.4348513834489541,-0.334793033079157,-0.05057146887282142,0.35713869105956414,0.7343412937617894,-0.8322673872621336,0.661098451902834,-1.0363129992676252,-0.029373324329508732,-0.3573554842529024,0.47326486642030946,0.35713869105956414,0.09594659045201429,0.0545236662877855,0.8954241674177924,-0.5182986952552782,1.4942024923485768,-0.334793033079157 | 3,040 |
Proteasome B-type subunit [IPR023333] | 6 | 7 | 2.519274 | 0.01176 | P28070,P49721,P28072,P49720,P28074,P20618 | Sequence | InterPro Family | interpro_family | 193,142,277,278,312,154 | 154,193,277,312,278,142,420 | 1.7550590252104994,1.509903867033398,1.2033338913699734,1.0687216574483722,1.2033338913699734,1.8294352882830525,0.8244516693582026 | 3,040 |
Proteasome core complex beta subunit complex | 6 | 7 | 2.519274 | 0.01176 | P28070,P49721,P28072,P49720,P28074,P20618 | Localization | GO Cellular component | msigdb_gocc | 193,142,277,278,312,154 | 154,193,277,312,278,142,420 | 1.7550590252104994,1.509903867033398,1.2033338913699734,1.0687216574483722,1.2033338913699734,1.8294352882830525,0.8244516693582026 | 3,040 |
protease | 13 | 41 | 2.518535 | 0.011784 | Q9BT78,P28070,Q99436,P49721,O75976,Q9UJ14,P28072,P49720,P61009,P28074,P60900,P50579,P20618 | Functions | Panther Protein class | panther_protein_class | 324,193,420,142,298,180,277,278,409,312,85,216,154 | 2564,2807,998,298,1930,425,2178,154,2445,2007,1082,1083,1823,193,277,312,2720,1897,1790,278,142,216,1593,85,409,1335,1900,2346,1865,677,2093,420,2103,324,1719,782,598,180,1583,1465,1783 | -0.7826010790948131,-1.088736557366239,0.21819012730572218,1.1196073499123598,-0.334793033079157,0.8065551874323789,-0.49497664277843795,1.7550590252104994,-0.6847954503580282,-0.3800230309908234,0.1574422653969169,0.1574422653969169,-0.26772543458963366,1.509903867033398,1.2033338913699734,1.0687216574483722,-0.9587584321347755,-0.312334586919792,-0.2455726333366303,1.2033338913699734,1.8294352882830525,1.3990093317163634,-0.13628593823390364,2.2006057669567936,0.8422863325591908,0.012752580513801317,-0.312334586919792,-0.6127320061884703,-0.2899790727297725,0.5113897708571208,-0.42567786323215334,0.8244516693582026,-0.42567786323215334,1.0516490831696563,-0.2015654664810097,0.4348513834489541,0.6054709229335996,1.6031550889336454,-0.11471723023422291,-0.05057146887282142,-0.22351964620585527 | 3,040 |
Abnormal renal cortex morphology | 16 | 55 | 2.517773 | 0.01181 | P00403,P00846,P00813,Q86WC4,P06280,Q8NFH4,Q8N1F7,Q9NQH7,O43826,Q14C86,Q12769,Q14108,Q9NZ08,P03886,Q6PGP7,O95470 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 436,6,8,168,297,267,430,106,396,364,380,52,84,54,340,405 | 1150,396,1324,1286,586,1152,2538,405,436,8,6,1554,2073,54,297,2473,2147,2761,1377,2239,1963,2341,2794,2903,2795,1657,1623,2154,607,1663,2986,1298,1262,459,380,52,364,2552,961,2928,1015,340,168,430,267,1713,1498,854,1272,706,562,106,2910,84,1464 | 0.11652951958878897,0.8600596556567248,0.012752580513801317,0.03368205509537154,0.6054709229335996,0.11652951958878897,-0.75796101573055,0.8422863325591908,0.7885964023248992,4.115215060881295,4.290668707384786,-0.11471723023422291,-0.42567786323215334,2.739511278775411,1.1364599089502991,-0.7090596464820835,-0.4717666193892306,-1.0103191649269512,-0.008265595708049227,-0.5417340014635557,-0.3573554842529024,-0.6127320061884703,-1.062451521523199,-1.3322148977448487,-1.062451521523199,-0.17970910315454527,-0.1579495805967917,-0.4717666193892306,0.5867930584046154,-0.17970910315454527,-1.8616370106422162,0.03368205509537154,0.0545236662877855,0.7705748236465301,0.8954241674177924,2.7894153625147196,0.9305489204651839,-0.75796101573055,0.25828324277369913,-1.444675674895682,0.21819012730572218,1.000093579058044,1.6796433852720836,0.8065551874323789,1.2529369403504902,-0.2015654664810097,-0.07186090588440568,0.35713869105956414,0.0545236662877855,0.4923630858030608,0.6426230676699337,2.0608146287550606,-1.3600739325016569,2.214391369466817,-0.05057146887282142 | 3,040 |
Organophosphate ester transmembrane transporter activity | 8 | 13 | 2.512772 | 0.011979 | Q9BSK2,Q9H2D1,O43826,P41440,O00400,Q9HC21,Q99808,Q8TB61 | Functions | GO Molecular function | msigdb_gomf | 171,46,396,239,20,708,93,540 | 20,1370,396,1288,867,698,239,1836,540,93,171,46,708 | 3.5772458059331473,-0.008265595708049227,0.8600596556567248,0.03368205509537154,0.33752223620233285,0.4923630858030608,1.3345857255664315,-0.26772543458963366,0.661098451902834,2.145115533980319,1.6644326324480352,2.900116777063521,0.4923630858030608 | 3,040 |
Sterol binding | 6 | 17 | 2.508484 | 0.012125 | O15118,P21796,P45880,Q14108,Q96SU4,Q14849 | Functions | GO Molecular function | msigdb_gomf | 98,12,14,52,87,152 | 98,2958,2301,644,1518,12,570,2150,289,14,2448,52,152,87,596,1878,967 | 2.089059189581746,-1.618710430813493,-0.5889493789129632,0.5492309315430891,-0.09324252520289562,3.8419900405287315,0.624080740847125,-0.4717666193892306,1.170003381143128,3.810841292230224,-0.6847954503580282,2.7894153625147196,1.7700163914806484,2.2006057669567936,0.6054709229335996,-0.2899790727297725,0.25828324277369913 | 3,040 |
Cellular ion homeostasis | 16 | 82 | 2.502413 | 0.012335 | Q7L0J3,P78417,P02786,Q9HD20,Q8N511,P62942,P05067,Q9HC07,Q9Y487,P50897,Q9P246,Q8IYU8,Q9H4I9,O75503,P09601,Q93050 | Processes and pathways | GO Biological process | msigdb_gobp | 65,130,219,40,105,11,74,175,177,120,248,372,252,91,284,323 | 1609,2844,1587,2299,386,2036,91,2206,2070,1886,2881,2471,2406,219,1476,74,1741,2408,1518,1556,284,1218,806,2337,958,2373,519,1616,1654,2443,2081,1786,2340,1402,2545,1059,1293,120,1333,1258,469,2266,1564,1624,2268,1449,11,130,790,811,2891,1764,941,979,2518,65,594,372,105,2813,2607,813,323,1143,1272,1173,1576,1175,832,2611,252,175,40,248,710,1509,2585,1363,177,2295,712,1106 | -0.1579495805967917,-1.1684895504192612,-0.13628593823390364,-0.5889493789129632,0.8777721115317447,-0.4027967817372936,2.1590406610189636,-0.5182986952552782,-0.42567786323215334,-0.312334586919792,-1.24963046884146,-0.7090596464820835,-0.6606536956722414,1.3829766872888838,-0.07186090588440568,2.2963894486711554,-0.22351964620585527,-0.6606536956722414,-0.09324252520289562,-0.11471723023422291,1.186695066202737,0.07527824008221333,0.39614435776678325,-0.6127320061884703,0.25828324277369913,-0.6366330002875932,0.6795074351426921,-0.1579495805967917,-0.17970910315454527,-0.6847954503580282,-0.42567786323215334,-0.2455726333366303,-0.6127320061884703,-0.029373324329508732,-0.75796101573055,0.1777736295870345,0.03368205509537154,1.960793573015321,0.012752580513801317,0.0545236662877855,0.7524899549765799,-0.5652838070018109,-0.11471723023422291,-0.1579495805967917,-0.5652838070018109,-0.05057146887282142,3.8626651909366387,1.9028038748611003,0.4155348788904062,0.39614435776678325,-1.2769953776362524,-0.22351964620585527,0.2782103405843624,0.23827674360495169,-0.7334476908882873,2.4962294121503965,0.6054709229335996,0.9130162849921596,2.0608146287550606,-1.088736557366239,-0.8073693656405042,0.39614435776678325,1.0516490831696563,0.13702781813267018,0.0545236662877855,0.11652951958878897,-0.11471723023422291,0.11652951958878897,0.3766791785599655,-0.8073693656405042,1.3020775180976913,1.649178704645811,3.0444444324111646,1.3183566065504058,0.4923630858030608,-0.07186090588440568,-0.7826010790948131,0.012752580513801317,1.649178704645811,-0.5652838070018109,0.4923630858030608,0.1574422653969169 | 3,040 |
Uch proteinases | 12 | 42 | 2.500586 | 0.012399 | Q92530,P28070,P61289,P49721,Q9UL46,P28072,P49720,P60900,P28074,O96019,Q8NB78,P20618 | Processes and pathways | Reactome Pathways | msigdb_reactome | 322,193,293,142,238,277,278,85,312,346,126,154 | 642,2564,1470,2807,1186,998,1188,346,2178,154,2445,2007,1082,1083,1823,193,277,312,2720,1897,1790,278,142,2828,1444,1593,85,293,1335,1900,2346,776,1865,1340,126,322,420,2103,238,1583,1679,1955 | 0.5492309315430891,-0.7826010790948131,-0.07186090588440568,-1.088736557366239,0.09594659045201429,0.21819012730572218,0.09594659045201429,0.982794416200427,-0.49497664277843795,1.7550590252104994,-0.6847954503580282,-0.3800230309908234,0.1574422653969169,0.1574422653969169,-0.26772543458963366,1.509903867033398,1.2033338913699734,1.0687216574483722,-0.9587584321347755,-0.312334586919792,-0.2455726333366303,1.2033338913699734,1.8294352882830525,-1.1151699685618548,-0.05057146887282142,-0.13628593823390364,2.2006057669567936,1.153258456656166,0.012752580513801317,-0.312334586919792,-0.6127320061884703,0.4348513834489541,-0.2899790727297725,0.012752580513801317,1.9318759771760645,1.0516490831696563,0.8244516693582026,-0.42567786323215334,1.3507652191046324,-0.11471723023422291,-0.17970910315454527,-0.334793033079157 | 3,040 |
Low set posteriorly rotated ears | 15 | 68 | 2.499003 | 0.012454 | O96028,O60566,Q15392,Q96L58,Q9Y263,Q8NCH0,Q15555,Q10713,Q4J6C6,P04062,P37268,O43924,O75530,P40855,P16435 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 161,287,7,327,139,170,365,250,61,243,53,23,215,348,285 | 1214,2033,1957,23,1550,287,1327,215,1820,2881,161,243,518,1555,2372,285,2239,1402,1562,53,348,933,1086,2155,1595,2415,2997,877,2986,1828,1409,777,792,250,2515,793,1228,2219,7,1869,365,1452,1131,61,503,1835,1015,1836,2051,170,2024,855,327,2580,2106,1847,2168,1677,690,2065,1363,992,2032,139,2468,421,1365,2403 | 0.07527824008221333,-0.4027967817372936,-0.3573554842529024,3.4568631579686766,-0.11471723023422291,1.170003381143128,0.012752580513801317,1.3990093317163634,-0.26772543458963366,-1.24963046884146,1.7250193216134055,1.3183566065504058,0.6795074351426921,-0.11471723023422291,-0.6366330002875932,1.186695066202737,-0.5417340014635557,-0.029373324329508732,-0.11471723023422291,2.776980594626845,0.982794416200427,0.2782103405843624,0.1574422653969169,-0.4717666193892306,-0.13628593823390364,-0.6606536956722414,-2.0204139562177725,0.33752223620233285,-1.8616370106422162,-0.26772543458963366,-0.029373324329508732,0.4348513834489541,0.4155348788904062,1.3020775180976913,-0.7334476908882873,0.4155348788904062,0.07527824008221333,-0.5182986952552782,4.164468347330218,-0.2899790727297725,0.9305489204651839,-0.05057146887282142,0.13702781813267018,2.599952157387,0.7161283312130348,-0.26772543458963366,0.21819012730572218,-0.26772543458963366,-0.4027967817372936,1.6644326324480352,-0.3800230309908234,0.35713869105956414,1.0345204898018696,-0.7826010790948131,-0.42567786323215334,-0.26772543458963366,-0.4717666193892306,-0.17970910315454527,0.5113897708571208,-0.4027967817372936,0.012752580513801317,0.23827674360495169,-0.3800230309908234,1.8589019195979646,-0.6847954503580282,0.8244516693582026,0.012752580513801317,-0.6366330002875932 | 3,040 |
Nephrotic syndrome | 11 | 25 | 2.498715 | 0.012464 | Q07021,P00813,P06280,Q8N1F7,Q8NCH0,Q9NPF4,Q05655,Q12769,Q14108,Q9BT22,O95470 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 573,8,297,430,170,562,459,380,52,545,405 | 405,1931,8,297,2147,1752,1623,1447,607,1262,459,573,380,52,1916,430,170,1498,854,1272,545,706,2106,562,2910 | 0.8422863325591908,-0.334793033079157,4.115215060881295,1.1364599089502991,-0.4717666193892306,-0.22351964620585527,-0.1579495805967917,-0.05057146887282142,0.5867930584046154,0.0545236662877855,0.7705748236465301,0.624080740847125,0.8954241674177924,2.7894153625147196,-0.312334586919792,0.8065551874323789,1.6644326324480352,-0.07186090588440568,0.35713869105956414,0.0545236662877855,0.661098451902834,0.4923630858030608,-0.42567786323215334,0.6426230676699337,-1.3600739325016569 | 3,040 |
Proteasome core complex | 8 | 15 | 2.495651 | 0.012573 | Q92530,P28070,P49721,P28072,P49720,P60900,P28074,P20618 | Localization | GO Cellular component | msigdb_gocc | 322,193,142,277,278,85,312,154 | 2807,154,2445,2007,1082,1083,1823,193,277,312,278,142,85,322,420 | -1.088736557366239,1.7550590252104994,-0.6847954503580282,-0.3800230309908234,0.1574422653969169,0.1574422653969169,-0.26772543458963366,1.509903867033398,1.2033338913699734,1.0687216574483722,1.2033338913699734,1.8294352882830525,2.2006057669567936,1.0516490831696563,0.8244516693582026 | 3,040 |
Organic acid transmembrane transporter activity | 7 | 17 | 2.487785 | 0.012854 | P08183,Q9H2D1,P41440,Q9UJS0,Q9UBX3,P53985,Q9Y619 | Functions | GO Molecular function | msigdb_gomf | 66,46,239,307,451,26,125 | 1929,1436,66,1081,239,771,26,1298,2454,2699,504,46,1539,2233,451,307,125 | -0.334793033079157,-0.05057146887282142,2.4831277053176017,0.1574422653969169,1.3345857255664315,0.4348513834489541,3.3901366110400533,0.03368205509537154,-0.6847954503580282,-0.907755404541169,0.7161283312130348,2.900116777063521,-0.09324252520289562,-0.5182986952552782,0.7885964023248992,1.1027003870412346,1.946353972838871 | 3,040 |
Glycerophospholipid biosynthetic process | 10 | 45 | 2.480494 | 0.01312 | Q9HBU6,Q9UG56,Q96PE3,Q9NPH0,Q6P1A2,Q92643,Q10713,P35790,Q96N66,Q9NUQ2 | Processes and pathways | GO Biological process | msigdb_gobp | 34,164,137,19,151,223,250,92,224,255 | 1547,517,1549,1399,886,2663,2735,1738,2078,92,1862,2765,2853,2986,460,250,1572,503,1707,151,300,1268,634,1773,2830,1390,1575,223,897,224,137,1043,2199,1274,857,1536,1208,34,1579,19,1242,255,1990,2398,164 | -0.11471723023422291,0.6795074351426921,-0.11471723023422291,-0.029373324329508732,0.3178291459077337,-0.8824588236038856,-0.9844682279779907,-0.22351964620585527,-0.42567786323215334,2.145115533980319,-0.2899790727297725,-1.0103191649269512,-1.1684895504192612,-1.8616370106422162,0.7705748236465301,1.3020775180976913,-0.11471723023422291,0.7161283312130348,-0.2015654664810097,1.7849324461832374,1.1196073499123598,0.0545236662877855,0.5680465845888625,-0.22351964620585527,-1.1151699685618548,-0.008265595708049227,-0.11471723023422291,1.3829766872888838,0.3178291459077337,1.3829766872888838,1.8735753952262877,0.19802266801457014,-0.49497664277843795,0.0545236662877855,0.35713869105956414,-0.09324252520289562,0.09594659045201429,3.1503484036762917,-0.11471723023422291,3.5880677323456616,0.07527824008221333,1.2857481125261092,-0.3573554842529024,-0.6366330002875932,1.7250193216134055 | 3,040 |
Lipid droplet | 8 | 34 | 2.47887 | 0.01318 | Q99720,Q01105,Q8NBX0,Q7L5N7,Q9H6V9,P48449,O43760,P09455 | Localization | GO Cellular component | msigdb_gocc | 69,354,9,300,48,245,336,63 | 2115,336,1286,2636,886,1614,2596,2441,63,245,1443,1333,1258,2344,427,354,721,1228,2978,1803,300,1711,1018,9,1773,2099,2226,1777,69,1462,48,1677,1645,1026 | -0.44866742092299217,1.000093579058044,0.03368205509537154,-0.8572966837718823,0.3178291459077337,-0.1579495805967917,-0.8073693656405042,-0.6847954503580282,2.574201082420162,1.3183566065504058,-0.05057146887282142,0.012752580513801317,0.0545236662877855,-0.6127320061884703,0.8065551874323789,0.965437543137018,0.47326486642030946,0.07527824008221333,-1.7690017501469077,-0.2455726333366303,1.1196073499123598,-0.2015654664810097,0.21819012730572218,3.9751084735818023,-0.22351964620585527,-0.42567786323215334,-0.5182986952552782,-0.22351964620585527,2.390543045095957,-0.05057146887282142,2.8879227390379008,-0.17970910315454527,-0.1579495805967917,0.21819012730572218 | 3,040 |
Disorders of transmembrane transporters | 19 | 75 | 2.476384 | 0.013272 | Q8NFH4,P49721,Q9BTX1,O00400,P28072,P49720,P53985,P20618,Q99436,P61289,Q8N1F7,Q99567,P28074,P35613,Q92530,P28070,P60900,Q9UL46,Q12769 | Processes and pathways | Reactome Pathways | msigdb_reactome | 267,142,143,20,277,278,26,154,420,293,430,306,312,313,322,193,85,238,380 | 642,2564,20,1470,2807,623,998,2958,1079,1188,2301,1081,973,2336,2178,1744,154,2445,2007,1082,1083,1823,193,277,312,313,2042,2720,1523,1897,1790,278,142,2601,1592,1444,719,26,1593,2344,607,85,293,1335,1900,2346,2450,776,380,1865,1340,2316,2699,965,430,1873,267,1457,1042,1498,322,854,446,420,2103,306,143,496,2752,706,1048,653,2432,238,1583 | 0.5492309315430891,-0.7826010790948131,3.5772458059331473,-0.07186090588440568,-1.088736557366239,0.5680465845888625,0.21819012730572218,-1.618710430813493,0.1574422653969169,0.09594659045201429,-0.5889493789129632,0.1574422653969169,0.23827674360495169,-0.6127320061884703,-0.49497664277843795,-0.22351964620585527,1.7550590252104994,-0.6847954503580282,-0.3800230309908234,0.1574422653969169,0.1574422653969169,-0.26772543458963366,1.509903867033398,1.2033338913699734,1.0687216574483722,1.0687216574483722,-0.4027967817372936,-0.9587584321347755,-0.09324252520289562,-0.312334586919792,-0.2455726333366303,1.2033338913699734,1.8294352882830525,-0.8073693656405042,-0.13628593823390364,-0.05057146887282142,0.47326486642030946,3.3901366110400533,-0.13628593823390364,-0.6127320061884703,0.5867930584046154,2.2006057669567936,1.153258456656166,0.012752580513801317,-0.312334586919792,-0.6127320061884703,-0.6847954503580282,0.4348513834489541,0.8954241674177924,-0.2899790727297725,0.012752580513801317,-0.5889493789129632,-0.907755404541169,0.25828324277369913,0.8065551874323789,-0.2899790727297725,1.2529369403504902,-0.05057146887282142,0.19802266801457014,-0.07186090588440568,1.0516490831696563,0.35713869105956414,0.7885964023248992,0.8244516693582026,-0.42567786323215334,1.1027003870412346,1.8294352882830525,0.7343412937617894,-0.9844682279779907,0.4923630858030608,0.19802266801457014,0.5492309315430891,-0.6606536956722414,1.3507652191046324,-0.11471723023422291 | 3,040 |
Ion homeostasis | 20 | 97 | 2.475879 | 0.013291 | P78417,O60826,P62942,P09601,Q9HD20,Q9HC07,Q9HD47,Q9Y487,Q93050,Q7L0J3,P30519,P05067,O75503,P02786,Q8N511,P63244,P50897,Q9P246,Q8IYU8,Q9H4I9 | Processes and pathways | GO Biological process | msigdb_gobp | 130,386,11,284,40,175,176,177,323,65,70,74,91,219,105,114,120,248,372,252 | 1609,2844,1587,2299,386,2036,91,2206,2070,1886,2790,2881,2471,2406,219,2937,1117,1476,74,1741,2408,1518,1556,284,2442,1218,806,2337,958,2373,519,1616,1654,2443,2081,1786,2340,1402,70,2545,1059,1293,606,120,1333,1258,469,2266,1564,1624,2268,1449,11,114,130,790,811,1632,2891,1197,1764,941,979,2518,65,594,372,105,419,2813,2607,813,323,1143,1272,1173,1576,1175,832,2631,2611,1721,252,175,40,176,248,710,1509,2585,1363,177,2295,3001,712,1106,1027 | -0.1579495805967917,-1.1684895504192612,-0.13628593823390364,-0.5889493789129632,0.8777721115317447,-0.4027967817372936,2.1590406610189636,-0.5182986952552782,-0.42567786323215334,-0.312334586919792,-1.062451521523199,-1.24963046884146,-0.7090596464820835,-0.6606536956722414,1.3829766872888838,-1.5019546528638092,0.13702781813267018,-0.07186090588440568,2.2963894486711554,-0.22351964620585527,-0.6606536956722414,-0.09324252520289562,-0.11471723023422291,1.186695066202737,-0.6847954503580282,0.07527824008221333,0.39614435776678325,-0.6127320061884703,0.25828324277369913,-0.6366330002875932,0.6795074351426921,-0.1579495805967917,-0.17970910315454527,-0.6847954503580282,-0.42567786323215334,-0.2455726333366303,-0.6127320061884703,-0.029373324329508732,2.377189975700653,-0.75796101573055,0.1777736295870345,0.03368205509537154,0.5867930584046154,1.960793573015321,0.012752580513801317,0.0545236662877855,0.7524899549765799,-0.5652838070018109,-0.11471723023422291,-0.1579495805967917,-0.5652838070018109,-0.05057146887282142,3.8626651909366387,1.9895584986314332,1.9028038748611003,0.4155348788904062,0.39614435776678325,-0.1579495805967917,-1.2769953776362524,0.09594659045201429,-0.22351964620585527,0.2782103405843624,0.23827674360495169,-0.7334476908882873,2.4962294121503965,0.6054709229335996,0.9130162849921596,2.0608146287550606,0.8244516693582026,-1.088736557366239,-0.8073693656405042,0.39614435776678325,1.0516490831696563,0.13702781813267018,0.0545236662877855,0.11652951958878897,-0.11471723023422291,0.11652951958878897,0.3766791785599655,-0.8322673872621336,-0.8073693656405042,-0.2015654664810097,1.3020775180976913,1.649178704645811,3.0444444324111646,1.649178704645811,1.3183566065504058,0.4923630858030608,-0.07186090588440568,-0.7826010790948131,0.012752580513801317,1.649178704645811,-0.5652838070018109,-2.052859180393565,0.4923630858030608,0.1574422653969169,0.21819012730572218 | 3,040 |
Isoprenoid metabolic process | 8 | 25 | 2.474904 | 0.013327 | O94788,Q9HBH5,Q6NUM9,Q9BY49,P48449,P37268,Q9HB40,P09455 | Processes and pathways | GO Biological process | msigdb_gobp | 134,232,266,210,245,53,121,63 | 369,533,1399,134,63,1219,887,2039,1290,53,245,659,2448,2874,1800,2484,2277,266,1138,681,1774,210,121,232,803 | 0.9130162849921596,0.661098451902834,-0.029373324329508732,1.8735753952262877,2.574201082420162,0.07527824008221333,0.3178291459077337,-0.4027967817372936,0.03368205509537154,2.776980594626845,1.3183566065504058,0.5303455219239778,-0.6847954503580282,-1.2224259209783335,-0.2455726333366303,-0.7090596464820835,-0.5652838070018109,1.2529369403504902,0.13702781813267018,0.5113897708571208,-0.22351964620585527,1.4309300892669885,1.960793573015321,1.366895427454461,0.4155348788904062 | 3,040 |
Protein targeting to membrane | 7 | 33 | 2.474443 | 0.013344 | O60725,O00560,P46379,P43307,Q9UHB9,Q15629,P40855 | Processes and pathways | GO Biological process | msigdb_gobp | 0,256,15,240,21,153,348 | 2141,256,1112,862,0,1887,1589,2303,406,2342,508,2264,348,240,15,890,1086,2213,2183,1663,811,960,153,2774,881,1537,2323,1428,1210,21,710,1076,2403 | -0.4717666193892306,1.2693680383752384,0.13702781813267018,0.33752223620233285,4.663254621455635,-0.312334586919792,-0.13628593823390364,-0.5889493789129632,0.8422863325591908,-0.6127320061884703,0.6978505521998537,-0.5652838070018109,0.982794416200427,1.3345857255664315,3.8004218159619,0.3178291459077337,0.1574422653969169,-0.5182986952552782,-0.49497664277843795,-0.17970910315454527,0.39614435776678325,0.25828324277369913,1.7700163914806484,-1.0103191649269512,0.33752223620233285,-0.09324252520289562,-0.5889493789129632,-0.029373324329508732,0.09594659045201429,3.566403837715786,0.4923630858030608,0.1777736295870345,-0.6366330002875932 | 3,040 |
Intrinsic component of mitochondrial inner membrane | 16 | 34 | 2.470345 | 0.013498 | Q9UG56,Q13505,Q9Y512,O60830,Q15070,Q9Y2R0,P17152,Q53H12,Q5XKP0,Q9H3K2,Q9NVH1,O75431,Q6P4A7,Q9H4I9,Q99595,O14925 | Localization | GO Cellular component | msigdb_gocc | 164,122,565,10,461,159,482,678,680,375,449,586,633,252,27,654 | 654,1587,10,586,2206,1436,482,2982,2378,1092,122,461,961,979,678,680,633,1165,1982,2813,27,1045,375,252,2233,1723,708,449,950,164,159,2295,565,1027 | 0.5303455219239778,-0.13628593823390364,3.954821843698463,0.6054709229335996,-0.5182986952552782,-0.05057146887282142,0.7343412937617894,-1.7996688507524958,-0.6366330002875932,0.1574422653969169,1.946353972838871,0.7705748236465301,0.25828324277369913,0.23827674360495169,0.5113897708571208,0.5113897708571208,0.5680465845888625,0.11652951958878897,-0.3573554842529024,-1.088736557366239,3.3564837478869274,0.19802266801457014,0.9130162849921596,1.3020775180976913,-0.5182986952552782,-0.2015654664810097,0.4923630858030608,0.7885964023248992,0.2782103405843624,1.7250193216134055,1.7550590252104994,-0.5652838070018109,0.6426230676699337,0.21819012730572218 | 3,040 |
Phospholipid biosynthesis | 6 | 17 | 2.445627 | 0.01446 | Q9HBU6,Q9UG56,Q6P1A2,P35790,Q96N66,Q9NUQ2 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 34,164,151,92,224,255 | 517,2663,92,2765,151,300,1268,1773,1390,2052,224,1274,34,1579,2633,255,164 | 0.6795074351426921,-0.8824588236038856,2.145115533980319,-1.0103191649269512,1.7849324461832374,1.1196073499123598,0.0545236662877855,-0.22351964620585527,-0.008265595708049227,-0.4027967817372936,1.3829766872888838,0.0545236662877855,3.1503484036762917,-0.11471723023422291,-0.8322673872621336,1.2857481125261092,1.7250193216134055 | 3,040 |
Glycosyl compound metabolic process | 10 | 27 | 2.437465 | 0.014791 | O60725,P08236,Q13126,Q9NUJ1,P00813,P06280,P04062,P04066,Q9BTY2,P31939 | Processes and pathways | GO Biological process | msigdb_gobp | 0,192,3,39,8,297,243,211,447,337 | 1398,2953,1856,0,1858,1516,8,243,211,1588,297,2472,192,2372,2076,1892,2039,1689,337,3035,1257,847,1090,470,3,447,39 | -0.029373324329508732,-1.589240151276104,-0.2899790727297725,4.663254621455635,-0.2899790727297725,-0.09324252520289562,4.115215060881295,1.3183566065504058,1.414993690331867,-0.13628593823390364,1.1364599089502991,-0.7090596464820835,1.525559168791652,-0.6366330002875932,-0.42567786323215334,-0.312334586919792,-0.4027967817372936,-0.2015654664810097,1.000093579058044,-4.200786896167727,0.0545236662877855,0.35713869105956414,0.1574422653969169,0.7524899549765799,4.479815010127175,0.7885964023248992,3.0799635941056946 | 3,040 |
G1 s dna damage checkpoints | 11 | 40 | 2.437393 | 0.014794 | Q92530,P28070,P61289,P49721,Q9UL46,P28072,P49720,P24941,P28074,P60900,P20618 | Processes and pathways | Reactome Pathways | msigdb_reactome | 322,193,293,142,238,277,278,212,312,85,154 | 642,2564,1470,2201,2807,998,1188,1738,1740,2178,154,212,2445,2007,1082,1083,1823,193,277,312,2720,1897,1790,278,142,1444,1593,85,293,1335,1900,2346,776,1865,1340,322,420,2103,238,1583 | 0.5492309315430891,-0.7826010790948131,-0.07186090588440568,-0.5182986952552782,-1.088736557366239,0.21819012730572218,0.09594659045201429,-0.22351964620585527,-0.22351964620585527,-0.49497664277843795,1.7550590252104994,1.414993690331867,-0.6847954503580282,-0.3800230309908234,0.1574422653969169,0.1574422653969169,-0.26772543458963366,1.509903867033398,1.2033338913699734,1.0687216574483722,-0.9587584321347755,-0.312334586919792,-0.2455726333366303,1.2033338913699734,1.8294352882830525,-0.05057146887282142,-0.13628593823390364,2.2006057669567936,1.153258456656166,0.012752580513801317,-0.312334586919792,-0.6127320061884703,0.4348513834489541,-0.2899790727297725,0.012752580513801317,1.0516490831696563,0.8244516693582026,-0.42567786323215334,1.3507652191046324,-0.11471723023422291 | 3,040 |
Peptide ligand binding receptors | 6 | 7 | 2.433951 | 0.014935 | P42892,Q9BYT8,Q9NRV9,P05067,Q9NZJ7,P07602 | Processes and pathways | Reactome Pathways | msigdb_reactome | 67,360,200,74,345,244 | 467,74,244,67,360,200,345 | 0.7524899549765799,2.2963894486711554,1.3183566065504058,2.4436369051693405,0.965437543137018,1.4942024923485768,1.000093579058044 | 3,040 |
Class a 1 rhodopsin like receptors | 6 | 7 | 2.433951 | 0.014935 | P42892,Q9BYT8,Q9NRV9,P05067,Q9NZJ7,P07602 | Processes and pathways | Reactome Pathways | msigdb_reactome | 67,360,200,74,345,244 | 467,74,244,67,360,200,345 | 0.7524899549765799,2.2963894486711554,1.3183566065504058,2.4436369051693405,0.965437543137018,1.4942024923485768,1.000093579058044 | 3,040 |
Lipid homeostasis | 9 | 26 | 2.433532 | 0.014952 | O15118,Q9NP80,Q5BJF2,P35610,Q8WTV0,Q96CP7,Q9Y6C9,O15254,P09455 | Processes and pathways | GO Biological process | msigdb_gobp | 98,163,68,289,41,237,214,242,63 | 1109,98,242,353,2072,63,2006,975,289,742,2448,3016,893,68,2934,41,237,1946,1462,1579,163,1506,2584,2290,1467,214 | 0.13702781813267018,2.089059189581746,1.3183566065504058,0.965437543137018,-0.42567786323215334,2.574201082420162,-0.3800230309908234,0.23827674360495169,1.170003381143128,0.45409450442527205,-0.6847954503580282,-2.49788388362525,0.3178291459077337,2.4171533162766576,-1.4732257420217356,3.032555550251405,1.3507652191046324,-0.334793033079157,-0.05057146887282142,-0.11471723023422291,1.7250193216134055,-0.07186090588440568,-0.7826010790948131,-0.5652838070018109,-0.05057146887282142,1.414993690331867 | 3,040 |
Inorganic ion transmembrane transport | 27 | 106 | 2.429415 | 0.015123 | P78417,P00846,P62942,P21796,Q9UHG3,O43826,P16615,O00400,P27105,P21281,Q9HD20,Q9HC07,Q96ES6,Q9HD47,Q9UBX3,Q13423,P00403,P56134,P51790,Q9UDW1,Q96GC9,Q8N697,Q8IYU8,Q9P246,O75964,Q9H4I9,Q7KZN9 | Processes and pathways | GO Biological process | msigdb_gobp | 130,6,11,12,13,396,519,20,406,286,40,175,557,176,451,60,436,571,469,234,374,504,372,248,378,252,381 | 20,1586,2590,1150,396,2299,2036,957,2662,1551,2003,378,2881,1684,436,6,1476,1288,2689,1741,2441,1518,1081,2237,806,2822,1153,867,1891,519,1616,1654,1558,286,2079,2939,12,1860,2762,406,1786,2763,2545,1123,2896,871,2508,1059,1293,1480,2954,1863,469,1379,1564,1624,571,2643,2268,1663,1449,11,130,790,1092,811,1298,662,878,2966,60,2891,1197,381,594,372,1772,504,2813,557,374,1173,1576,2888,2775,2229,832,1504,1675,2611,1721,252,1539,175,40,176,248,451,234,710,13,1509,2585,1363,1584,2295 | 3.5772458059331473,-0.13628593823390364,-0.8073693656405042,0.11652951958878897,0.8600596556567248,-0.5889493789129632,-0.4027967817372936,0.25828324277369913,-0.8824588236038856,-0.11471723023422291,-0.3800230309908234,0.8954241674177924,-1.24963046884146,-0.2015654664810097,0.7885964023248992,4.290668707384786,-0.07186090588440568,0.03368205509537154,-0.907755404541169,-0.22351964620585527,-0.6847954503580282,-0.09324252520289562,0.1574422653969169,-0.5417340014635557,0.39614435776678325,-1.1151699685618548,0.11652951958878897,0.33752223620233285,-0.312334586919792,0.6795074351426921,-0.1579495805967917,-0.17970910315454527,-0.11471723023422291,1.186695066202737,-0.42567786323215334,-1.5019546528638092,3.8419900405287315,-0.2899790727297725,-1.0103191649269512,0.8422863325591908,-0.2455726333366303,-1.0103191649269512,-0.75796101573055,0.13702781813267018,-1.3045227910643165,0.33752223620233285,-0.7334476908882873,0.1777736295870345,0.03368205509537154,-0.07186090588440568,-1.589240151276104,-0.2899790727297725,0.7524899549765799,-0.008265595708049227,-0.11471723023422291,-0.1579495805967917,0.624080740847125,-0.8572966837718823,-0.5652838070018109,-0.17970910315454527,-0.05057146887282142,3.8626651909366387,1.9028038748611003,0.4155348788904062,0.1574422653969169,0.39614435776678325,0.03368205509537154,0.5303455219239778,0.33752223620233285,-1.6483728475080308,2.6127834871538127,-1.2769953776362524,0.09594659045201429,0.8954241674177924,0.6054709229335996,0.9130162849921596,-0.22351964620585527,0.7161283312130348,-1.088736557366239,0.6426230676699337,0.9130162849921596,0.11652951958878897,-0.11471723023422291,-1.24963046884146,-1.0103191649269512,-0.5182986952552782,0.3766791785599655,-0.07186090588440568,-0.17970910315454527,-0.8073693656405042,-0.2015654664810097,1.3020775180976913,-0.09324252520289562,1.649178704645811,3.0444444324111646,1.649178704645811,1.3183566065504058,0.7885964023248992,1.366895427454461,0.4923630858030608,3.8419900405287315,-0.07186090588440568,-0.7826010790948131,0.012752580513801317,-0.11471723023422291,-0.5652838070018109 | 3,040 |
Recruitment of mitotic centrosome proteins and complexes | 12 | 31 | 2.428807 | 0.015149 | Q13561,Q9H6D7,Q9BSJ2,P30153,O43805,O95684,P04350,O75935,P68371,P53350,P07437,Q96CS2 | Processes and pathways | Reactome Pathways | msigdb_reactome | 537,199,463,299,42,172,332,304,488,145,518,383 | 42,304,568,172,332,1000,518,2005,299,1085,1255,145,772,1937,1449,849,488,2626,537,2781,1413,1975,723,851,1199,1267,383,2131,2229,463,199 | 3.020641895229821,1.1027003870412346,0.624080740847125,1.649178704645811,1.0173354618632569,0.21819012730572218,0.6795074351426921,-0.3800230309908234,1.1196073499123598,0.1574422653969169,0.0545236662877855,1.8146416422908467,0.4348513834489541,-0.334793033079157,-0.05057146887282142,0.35713869105956414,0.7343412937617894,-0.8322673872621336,0.661098451902834,-1.0363129992676252,-0.029373324329508732,-0.3573554842529024,0.47326486642030946,0.35713869105956414,0.09594659045201429,0.0545236662877855,0.8954241674177924,-0.44866742092299217,-0.5182986952552782,0.7705748236465301,1.4942024923485768 | 3,040 |
Abnormal retinal artery morphology | 8 | 21 | 2.426771 | 0.015234 | P21964,P00846,P10619,P16278,P06865,Q9NZJ7,P07602,P03886 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 387,6,103,258,291,345,244,54 | 2871,1957,6,54,291,244,2408,103,2038,258,2307,387,1562,1445,2415,1866,2219,919,345,2065,421 | -1.2224259209783335,-0.3573554842529024,4.290668707384786,2.739511278775411,1.153258456656166,1.3183566065504058,-0.6606536956722414,2.074955115714817,-0.4027967817372936,1.2693680383752384,-0.5889493789129632,0.8777721115317447,-0.11471723023422291,-0.05057146887282142,-0.6606536956722414,-0.2899790727297725,-0.5182986952552782,0.29805874290970236,1.000093579058044,-0.4027967817372936,0.8244516693582026 | 3,040 |
Membrane protein complex | 61 | 283 | 2.413468 | 0.015802 | P00846,O00560,O60830,P62942,P21796,P22695,P45880,Q9P0J0,P61009,O15155,Q99595,O43676,O75438,P21281,P53680,O15269,Q86WC4,Q9C0H2,Q9P253,Q9Y487,Q9NVH1,P03886,O14949,Q9Y2T2,Q93050,P11717,P10321,P00403,Q53GQ0,Q08AM6,Q9Y584,Q96CU9,Q9Y277,O43752,Q9Y678,Q9NR28,Q9UBU6,Q92643,P02786,O14579,Q13190,Q9BUN8,Q86Y39,Q3ZCQ8,Q8N511,Q9UDW1,Q9NS69,Q9H4I9,O75964,Q14165,O75306,P35222,P41440,O43464,P62072,Q8IYU8,Q13277,P14406,O96000,Q13505,Q9Y3B3 | Localization | GO Cellular component | msigdb_gocc | 6,256,10,11,12,268,14,275,409,282,27,283,404,286,417,165,168,169,302,177,449,54,308,190,323,438,437,436,321,460,72,75,206,78,208,89,217,223,219,466,220,496,355,492,105,234,107,252,378,489,108,483,239,369,117,372,371,370,118,122,384 | 2536,1609,2361,1547,1586,256,2590,466,2844,2437,996,654,308,694,282,165,655,1249,1250,1549,2565,369,842,283,1113,78,2819,2833,1683,737,10,957,108,2503,2637,586,2537,404,1215,2003,1032,378,1251,767,1888,2439,696,2906,1736,2072,1931,1373,118,1189,436,6,1554,219,54,552,1080,2261,1117,1476,1288,2689,1741,2441,1081,2237,1555,1556,1375,2598,806,437,2822,2948,438,867,698,1891,370,2262,2960,929,2618,1558,286,2079,12,1963,268,1860,2762,2340,3019,2868,2763,2341,1123,2008,483,2824,808,871,2508,1059,2982,1896,239,2410,14,1480,520,2954,1694,1657,890,977,1968,1155,1379,1752,2412,1482,2154,417,1445,1564,1446,2344,1625,571,1793,2643,630,2213,1380,409,2268,1663,2345,2312,117,11,1260,1664,1125,1223,746,1864,1007,2417,574,460,2966,2048,2886,220,371,1632,122,2128,489,2217,2193,677,940,960,1064,1764,502,2158,941,2876,1012,979,492,321,678,1704,2162,680,2934,1165,168,355,726,1915,372,827,668,1772,105,1269,2972,2813,634,2773,797,1234,798,1838,1600,729,1775,223,919,323,897,1272,2226,75,756,527,1310,1043,2656,2199,27,2775,2321,1778,2229,832,1533,496,1045,169,1675,2231,985,2323,1208,252,1428,1948,1641,1924,89,859,107,449,2967,2430,950,275,302,922,2831,1245,1105,217,653,2499,234,1360,1210,2562,1509,2466,1182,2952,2433,2534,206,1397,190,2755,384,177,2295,565,72,2756,971,3001,208,1026,1106,1467,2992 | 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| 3,040 |
Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen | 9 | 34 | 2.413064 | 0.015819 | Q14534,Q6UW02,P30519,Q16850,Q15800,Q9BU89,P09601,P16435,Q8NB78 | Functions | GO Molecular function | msigdb_gomf | 319,294,70,18,179,187,284,285,126 | 2362,1548,1854,1433,1434,2998,2936,1328,2037,284,1687,285,1290,70,743,2271,1630,319,179,18,1134,2222,1768,294,2094,917,945,126,187,858,343,1950,564,2293 | -0.6366330002875932,-0.11471723023422291,-0.2899790727297725,-0.05057146887282142,-0.05057146887282142,-2.052859180393565,-1.5019546528638092,0.012752580513801317,-0.4027967817372936,1.186695066202737,-0.2015654664810097,1.186695066202737,0.03368205509537154,2.377189975700653,0.45409450442527205,-0.5652838070018109,-0.1579495805967917,1.0516490831696563,1.6185402139192084,3.631156676050709,0.13702781813267018,-0.5182986952552782,-0.22351964620585527,1.153258456656166,-0.42567786323215334,0.29805874290970236,0.2782103405843624,1.9318759771760645,1.5567327633064831,0.35713869105956414,1.000093579058044,-0.334793033079157,0.6426230676699337,-0.5652838070018109 | 3,040 |
Nucleophile aminohydrolases, N-terminal [IPR029055] | 9 | 19 | 2.404377 | 0.0162 | P28070,Q99436,P49721,Q9UJ14,P28072,P49720,P60900,P28074,P20618 | Sequence | InterPro Superfamily | interpro_homologous_superfamily | 193,420,142,180,277,278,85,312,154 | 2807,739,154,2445,2007,1082,1083,1823,193,277,312,278,142,85,470,612,2093,420,180 | -1.088736557366239,0.45409450442527205,1.7550590252104994,-0.6847954503580282,-0.3800230309908234,0.1574422653969169,0.1574422653969169,-0.26772543458963366,1.509903867033398,1.2033338913699734,1.0687216574483722,1.2033338913699734,1.8294352882830525,2.2006057669567936,0.7524899549765799,0.5867930584046154,-0.42567786323215334,0.8244516693582026,1.6031550889336454 | 3,040 |
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