term stringlengths 2 121 | overlap int64 6 281 | setsize int64 7 499 | score float64 1.96 10.6 | pval float64 0 0.05 | edge stringlengths 41 1.97k | type stringclasses 5 values | subtype stringclasses 24 values | subtype_key stringclasses 24 values | edge_idxs stringlengths 11 1.17k | ann_idxs stringlengths 19 2.31k | ann_vals stringlengths 124 9.94k | sig_size int64 2.2k 3.73k |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Abnormal biliary tract morphology | 9 | 24 | 2.493429 | 0.012652 | Q9NSD9,P07602,P09601,Q14108,Q10713,P04062,P50542,Q92889,Q14739 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 322,65,98,4,170,76,270,316,126 | 706,1385,76,65,98,511,2127,2774,2967,1081,270,2138,170,4,126,1863,316,1474,2500,322,598,405,2520,1436 | 0.3039647528659509,-0.08397003066656783,2.732827412432188,3.049800312599363,2.3402615879978588,0.5092850756510509,-0.3448944504989137,-0.6342192735405214,-0.7931210294366591,0.07168366704405241,1.0939960112015843,-0.3448944504989137,1.646238301853119,5.4604731281181715,2.0687191415996717,-0.24029329531427543,0.91687882319615,-0.10997668458835863,-0.47609517429475745,0.8915181244165605,0.43241340517931676,0.6880929270902055,-0.47609517429475745,-0.08397003066656783 | 3,246 |
Hydrolase activity acting on glycosyl bonds | 11 | 30 | 2.491516 | 0.01272 | P29372,P13051,P16278,Q01459,O60502,P04062,P10253,Q9NUJ1,O75503,P17900,P54802 | Functions | GO Molecular function | msigdb_gomf | 161,194,33,330,134,76,298,79,82,214,217 | 503,702,1498,134,82,76,630,370,2193,3105,1445,298,1580,194,33,214,1275,3057,161,2669,217,1086,330,1998,1926,1142,570,79,2837,3166 | 0.5092850756510509,0.3039647528659509,-0.1360020577956454,1.9448246105356892,2.634944712077862,2.732827412432188,0.38108381849412826,0.739040326321,-0.3710941852773667,-1.0062644931084461,-0.10997668458835863,0.9928729317279787,-0.1620462766525934,1.4712243043141844,3.7268890651643467,1.3458212477032034,-0.03201238316427893,-0.899505788360606,1.6961270173061391,-0.5814265778010619,1.3207004867153997,0.07168366704405241,0.8661426282602883,-0.29255459388450233,-0.2664141933665721,0.04578676244131425,0.4580535594777235,2.732827412432188,-0.6606479316905032,-1.2209550696577467 | 3,246 |
Alcohol binding | 6 | 16 | 2.487913 | 0.01285 | O15118,Q14108,P61916,O95772,P21796,P45880 | Functions | GO Molecular function | msigdb_gomf | 131,4,105,237,53,31 | 1662,131,1268,1224,249,237,2048,53,2818,3145,2873,31,105,4,2442,2948 | -0.18810946914769616,1.994418108265382,-0.03201238316427893,-0.006061144709344608,1.1696891723387541,1.2200813591990216,-0.31871463345796447,3.219774416782617,-0.6606479316905032,-1.1134097681064297,-0.713570697362591,3.7990028619728236,2.266341771441869,5.4604731281181715,-0.4498143273913549,-0.7665818624827188 | 3,246 |
Abnormality of femur morphology | 16 | 64 | 2.473212 | 0.01339 | Q9UHX1,P51798,P16278,P07602,Q96AY3,Q9Y487,Q9Y619,P04062,P50542,Q9BXW9,O75431,Q92889,P06280,Q14739,P51812,O75844 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 0,251,33,65,99,122,303,76,270,240,248,316,370,126,279,190 | 393,1813,2807,702,704,1439,2720,248,826,789,190,2869,528,529,1385,76,630,1669,370,2768,65,580,33,1272,2775,2728,2843,2874,3042,1331,270,251,279,1986,1084,1909,126,2974,2083,2300,769,2830,1141,1540,1050,2587,727,316,642,99,472,2016,1254,240,1257,1307,3232,1067,598,0,2386,122,1655,303 | 0.6880929270902055,-0.24029329531427543,-0.6606479316905032,0.3039647528659509,0.3039647528659509,-0.10997668458835863,-0.6078122100368903,1.1696891723387541,0.22669361755482975,0.25246773267811196,1.4962652266439553,-0.713570697362591,0.4836774176196852,0.4836774176196852,-0.08397003066656783,2.732827412432188,0.38108381849412826,-0.18810946914769616,0.739040326321,-0.6342192735405214,3.049800312599363,0.43241340517931676,3.7268890651643467,-0.03201238316427893,-0.6342192735405214,-0.6078122100368903,-0.6870983502389405,-0.713570697362591,-0.8728750171589886,-0.05798197126028844,1.0939960112015843,1.1696891723387541,1.0687366974464951,-0.29255459388450233,0.07168366704405241,-0.2664141933665721,2.0687191415996717,-0.7931210294366591,-0.31871463345796447,-0.39731397995833206,0.27822474270062764,-0.6606479316905032,0.04578676244131425,-0.1360020577956454,0.09756269387250471,-0.5287189651896583,0.3039647528659509,0.91687882319615,0.38108381849412826,2.3156329202480475,0.5604521702536023,-0.29255459388450233,-0.006061144709344608,1.2200813591990216,-0.006061144709344608,-0.03201238316427893,-2.2094772855618086,0.09756269387250471,0.43241340517931676,8.366255129812147,-0.4235539786397383,2.118194303237033,-0.1620462766525934,0.9928729317279787 | 3,246 |
Phospholipid binding | 15 | 93 | 2.466822 | 0.013632 | P07602,P50897,Q14108,O00291,Q9UM22,Q9Y5X1,Q96L92,Q9Y4G8,Q8NCC3,P21796,P53367,Q08431,Q8WTV0,Q9Y5X3,P45880 | Functions | GO Molecular function | msigdb_gomf | 65,66,4,288,9,141,208,81,52,53,55,314,29,324,31 | 1264,1657,288,1813,551,2522,787,3079,2334,705,1115,1816,1267,1820,942,2042,2956,871,1575,2195,65,1444,2048,1174,984,1579,2404,985,53,2130,1677,363,469,1594,31,3083,317,606,66,2825,55,637,756,1921,314,1993,880,3024,762,1287,4,881,2786,2975,2146,665,2906,2540,52,29,851,810,1418,1146,208,3075,1634,2441,2242,2981,2442,2948,1018,818,1065,1154,1727,598,2515,785,3052,901,499,695,9,1809,674,2330,81,464,141,324,481 | -0.03201238316427893,-0.18810946914769616,1.0181752334237035,-0.24029329531427543,0.4580535594777235,-0.5023966694843781,0.25246773267811196,-0.9528376270712595,-0.4235539786397383,0.3039647528659509,0.04578676244131425,-0.24029329531427543,-0.03201238316427893,-0.24029329531427543,0.14926757041348834,-0.31871463345796447,-0.7931210294366591,0.2009022908471458,-0.1620462766525934,-0.3710941852773667,3.049800312599363,-0.10997668458835863,-0.31871463345796447,0.019871864265687718,0.1234239573228073,-0.1620462766525934,-0.4498143273913549,0.1234239573228073,3.219774416782617,-0.3448944504989137,-0.18810946914769616,0.7644910395751178,0.5604521702536023,-0.1620462766525934,3.7990028619728236,-0.9528376270712595,0.8915181244165605,0.40675685759510555,2.8793375078697796,-0.6606479316905032,3.195521831934781,0.38108381849412826,0.27822474270062764,-0.2664141933665721,0.91687882319615,-0.29255459388450233,0.2009022908471458,-0.8462674242732842,0.27822474270062764,-0.03201238316427893,5.4604731281181715,0.2009022908471458,-0.6342192735405214,-0.7931210294366591,-0.3448944504989137,0.355394188525345,-0.7400651437154296,-0.5023966694843781,3.244017289535622,3.8470341251685394,0.22669361755482975,0.25246773267811196,-0.08397003066656783,0.04578676244131425,1.3960224207311585,-0.9261599274787706,-0.1620462766525934,-0.4498143273913549,-0.3710941852773667,-0.7931210294366591,-0.4498143273913549,-0.7665818624827188,0.1234239573228073,0.25246773267811196,0.09756269387250471,0.04578676244131425,-0.18810946914769616,0.43241340517931676,-0.47609517429475745,0.27822474270062764,-0.8728750171589886,0.2009022908471458,0.5348766285518468,0.32968786719872717,5.154797269034447,-0.21419176492469524,0.355394188525345,-0.39731397995833206,2.6839072164913147,0.5860117936562828,1.9200098581999967,0.8915181244165605,0.5604521702536023 | 3,246 |
Abnormality of the lymph nodes | 7 | 39 | 2.458561 | 0.01395 | P51798,P13051,Q9NZ08,P10644,P33991,P28070,Q5HYI8 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 251,194,35,222,8,142,178 | 1733,1027,2189,1169,2460,629,790,1669,2122,222,194,511,2204,142,1510,8,1749,1452,1398,950,251,2063,557,996,1918,2359,272,761,2786,1244,178,2538,1348,2156,1252,2097,3033,35,1560 | -0.21419176492469524,0.09756269387250471,-0.3710941852773667,0.019871864265687718,-0.47609517429475745,0.38108381849412826,0.25246773267811196,-0.18810946914769616,-0.3448944504989137,1.2955661860369987,1.4712243043141844,0.5092850756510509,-0.3710941852773667,1.8951830310030808,-0.1360020577956454,5.225447598312084,-0.21419176492469524,-0.10997668458835863,-0.08397003066656783,0.14926757041348834,1.1696891723387541,-0.31871463345796447,0.4580535594777235,0.1234239573228073,-0.2664141933665721,-0.4235539786397383,1.0939960112015843,0.27822474270062764,-0.6342192735405214,-0.006061144709344608,1.5962987576738683,-0.5023966694843781,-0.05798197126028844,-0.3448944504989137,-0.006061144709344608,-0.31871463345796447,-0.8462674242732842,3.7028331681230524,-0.1360020577956454 | 3,246 |
Mapk family signaling cascades | 21 | 90 | 2.45796 | 0.013973 | P49354,Q15334,P49721,Q9UL46,P28070,Q96S59,P49356,O60725,Q9HCE1,P61289,P20618,Q99956,O00231,P28072,O43924,P46940,P07196,Q9Y4G8,Q13555,P28074,P60900 | Processes and pathways | Reactome Pathways | msigdb_reactome | 1,386,5,406,142,403,146,30,294,408,290,302,304,184,64,317,327,81,338,224,114 | 304,3054,1315,1959,1495,3079,742,64,30,2610,654,747,944,327,1176,1325,1273,290,1587,1230,1179,1832,2203,2729,1897,1589,142,184,224,2843,1677,435,604,1234,1976,469,2730,910,2572,2619,317,1515,1,146,676,5,1983,3127,1847,114,2065,408,2935,840,1130,2355,954,2473,756,1041,1191,758,1529,957,338,1194,1092,718,1856,585,1698,386,1930,2850,2149,1791,778,403,617,1940,302,294,2598,1951,406,2557,3196,1491,2330,81 | 0.9675561480174244,-0.899505788360606,-0.05798197126028844,-0.29255459388450233,-0.1360020577956454,-0.9528376270712595,0.27822474270062764,3.074111943417051,3.7990028619728236,-0.5550622157783601,0.355394188525345,0.27822474270062764,0.14926757041348834,0.8661426282602883,0.019871864265687718,-0.05798197126028844,-0.03201238316427893,1.0181752334237035,-0.1620462766525934,-0.006061144709344608,0.019871864265687718,-0.24029329531427543,-0.3710941852773667,-0.6078122100368903,-0.2664141933665721,-0.1620462766525934,1.8951830310030808,1.5463078978712268,1.2955661860369987,-0.6870983502389405,-0.18810946914769616,0.6115555906448871,0.40675685759510555,-0.006061144709344608,-0.29255459388450233,0.5604521702536023,-0.6078122100368903,0.1750936448097422,-0.5287189651896583,-0.5550622157783601,0.8915181244165605,-0.1360020577956454,7.522780284208136,1.845492931563142,0.32968786719872717,5.413525936075921,-0.29255459388450233,-1.059787988728998,-0.24029329531427543,2.167622859137434,-0.31871463345796447,0.6625960679420675,-0.7665818624827188,0.22669361755482975,0.04578676244131425,-0.4235539786397383,0.14926757041348834,-0.47609517429475745,0.27822474270062764,0.09756269387250471,0.019871864265687718,0.27822474270062764,-0.1360020577956454,0.14926757041348834,0.8407522538471938,0.019871864265687718,0.07168366704405241,0.3039647528659509,-0.24029329531427543,0.43241340517931676,-0.18810946914769616,0.7135743175341883,-0.2664141933665721,-0.6870983502389405,-0.3448944504989137,-0.21419176492469524,0.27822474270062764,0.6880929270902055,0.40675685759510555,-0.2664141933665721,0.9928729317279787,1.0181752334237035,-0.5287189651896583,-0.2664141933665721,0.6880929270902055,-0.5023966694843781,-1.4916652636686065,-0.10997668458835863,-0.39731397995833206,2.6839072164913147 | 3,246 |
Carboxylic acid transport | 7 | 34 | 2.4489 | 0.014329 | Q7L0J3,P07602,Q9H2D1,Q9Y619,Q9UBX3,P41440,P30825 | Processes and pathways | GO Biological process | msigdb_gobp | 96,65,71,303,143,108,215 | 2391,296,788,1380,2397,1575,1269,65,2049,511,1747,215,108,2209,951,1084,1404,1137,2148,2944,96,1251,1479,967,71,1426,2323,2918,1640,2377,598,143,1312,303 | -0.4498143273913549,0.9928729317279787,0.25246773267811196,-0.08397003066656783,-0.4498143273913549,-0.1620462766525934,-0.03201238316427893,3.049800312599363,-0.31871463345796447,0.5092850756510509,-0.21419176492469524,1.3458212477032034,2.2416791937316303,-0.3710941852773667,0.14926757041348834,0.07168366704405241,-0.08397003066656783,0.04578676244131425,-0.3448944504989137,-0.7665818624827188,2.389485348920194,-0.006061144709344608,-0.10997668458835863,0.14926757041348834,2.854945010826298,-0.08397003066656783,-0.39731397995833206,-0.7400651437154296,-0.1620462766525934,-0.4235539786397383,0.43241340517931676,1.8951830310030808,-0.03201238316427893,0.9928729317279787 | 3,246 |
membrane trafficking regulatory protein | 9 | 19 | 2.441643 | 0.014621 | P24390,Q15334,Q14108,Q96EA4,O43760,P50542,O00560,Q13439,Q8WTV0 | Functions | Panther Protein class | panther_protein_class | 2,386,4,493,262,270,551,470,29 | 2389,550,551,262,2046,791,2,270,470,4,2146,386,29,2095,2544,493,1256,1646,2030 | -0.4498143273913549,0.4580535594777235,0.4580535594777235,1.119241145820181,-0.31871463345796447,0.25246773267811196,7.063640679323355,1.0939960112015843,0.5604521702536023,5.4604731281181715,-0.3448944504989137,0.7135743175341883,3.8470341251685394,-0.31871463345796447,-0.5023966694843781,0.5348766285518468,-0.006061144709344608,-0.1620462766525934,-0.29255459388450233 | 3,246 |
Abnormality of the spleen | 21 | 124 | 2.432784 | 0.014983 | P51798,O15118,Q14108,P33991,P28070,Q13510,P16278,Q9NZ08,Q10713,Q15392,Q15437,Q5HYI8,P07602,P10619,P04062,O96028,P54802,Q9NPE3,P61916,O95155,Q14739 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 251,131,4,8,142,272,33,35,170,46,177,178,65,199,76,213,217,226,105,244,126 | 2990,1659,1813,702,553,1663,131,1268,2868,2189,1119,2458,244,1501,2998,213,2460,629,790,1385,76,630,2767,1669,2665,2400,2122,65,3105,1445,2196,298,199,2770,2404,2726,580,1390,1322,511,530,33,1972,2872,337,1032,2129,2204,142,1747,1510,363,8,2930,2533,3230,1749,2779,2573,1081,1452,2057,950,2137,2138,251,2210,1128,2063,217,2578,3098,105,2213,1039,557,1918,1191,170,2679,272,761,1998,4,126,46,177,1288,1532,683,178,1861,769,428,1933,2231,562,2092,2587,1252,811,2543,2097,642,2544,472,2500,1209,855,1012,2370,1061,2701,3033,226,2028,35,598,1312,3166,698,3200,1160,1655 | -0.819682822993657,-0.18810946914769616,-0.24029329531427543,0.3039647528659509,0.4580535594777235,-0.18810946914769616,1.994418108265382,-0.03201238316427893,-0.713570697362591,-0.3710941852773667,0.04578676244131425,-0.47609517429475745,1.1948922097827732,-0.1360020577956454,-0.819682822993657,1.3458212477032034,-0.47609517429475745,0.38108381849412826,0.25246773267811196,-0.08397003066656783,2.732827412432188,0.38108381849412826,-0.6342192735405214,-0.18810946914769616,-0.5814265778010619,-0.4498143273913549,-0.3448944504989137,3.049800312599363,-1.0062644931084461,-0.10997668458835863,-0.3710941852773667,0.9928729317279787,1.4461702390450293,-0.6342192735405214,-0.4498143273913549,-0.6078122100368903,0.43241340517931676,-0.08397003066656783,-0.05798197126028844,0.5092850756510509,0.4836774176196852,3.7268890651643467,-0.29255459388450233,-0.713570697362591,0.8407522538471938,0.09756269387250471,-0.3448944504989137,-0.3710941852773667,1.8951830310030808,-0.21419176492469524,-0.1360020577956454,0.7644910395751178,5.225447598312084,-0.7665818624827188,-0.5023966694843781,-2.1814737775608597,-0.21419176492469524,-0.6342192735405214,-0.5287189651896583,0.07168366704405241,-0.10997668458835863,-0.31871463345796447,0.14926757041348834,-0.3448944504989137,-0.3448944504989137,1.1696891723387541,-0.3710941852773667,0.04578676244131425,-0.31871463345796447,1.3207004867153997,-0.5287189651896583,-0.9795390827213797,2.266341771441869,-0.3710941852773667,0.09756269387250471,0.4580535594777235,-0.2664141933665721,0.019871864265687718,1.646238301853119,-0.5814265778010619,1.0939960112015843,0.27822474270062764,-0.29255459388450233,5.4604731281181715,2.0687191415996717,3.3166879953213755,1.5962987576738683,-0.03201238316427893,-0.1360020577956454,0.32968786719872717,1.5962987576738683,-0.24029329531427543,0.27822474270062764,0.6370836521056745,-0.2664141933665721,-0.3710941852773667,0.4580535594777235,-0.31871463345796447,-0.5287189651896583,-0.006061144709344608,0.25246773267811196,-0.5023966694843781,-0.31871463345796447,0.38108381849412826,-0.5023966694843781,0.5604521702536023,-0.47609517429475745,0.019871864265687718,0.22669361755482975,0.1234239573228073,-0.4235539786397383,0.09756269387250471,-0.5814265778010619,-0.8462674242732842,1.2955661860369987,-0.29255459388450233,3.7028331681230524,0.43241340517931676,-0.03201238316427893,-1.2209550696577467,0.32968786719872717,-1.5461400051345588,0.04578676244131425,-0.1620462766525934 | 3,246 |
Intracellular protein transmembrane transport | 8 | 23 | 2.430612 | 0.015073 | Q15388,P31751,Q9Y5Y5,Q15629,O60830,O75298,P50542,Q99595 | Processes and pathways | GO Biological process | msigdb_gobp | 259,195,261,166,11,168,270,50 | 334,938,11,168,2338,1500,528,509,1969,580,195,270,2934,1909,1520,259,166,1345,1794,50,2246,648,261 | 0.8407522538471938,0.14926757041348834,4.895169327756598,1.646238301853119,-0.4235539786397383,-0.1360020577956454,0.4836774176196852,0.5092850756510509,-0.29255459388450233,0.43241340517931676,1.4712243043141844,1.0939960112015843,-0.7665818624827188,-0.2664141933665721,-0.1360020577956454,1.14447217515618,1.6711889830807138,-0.05798197126028844,-0.21419176492469524,3.2682504863299298,-0.3710941852773667,0.38108381849412826,1.14447217515618 | 3,246 |
Poor eye contact | 7 | 39 | 2.42297 | 0.015394 | Q9UHX1,Q5KU26,Q96CU9,O96000,Q9Y6M9,Q86Y39,O43676 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 0,69,73,203,145,282,95 | 95,2841,1666,2394,1380,203,2528,3134,1182,2782,1845,2209,994,756,716,1341,2360,1534,69,1863,282,2690,1298,1790,73,2321,2695,1717,2370,2371,1303,459,2836,2513,1311,295,0,701,145 | 2.4140805364413698,-0.6870983502389405,-0.18810946914769616,-0.4498143273913549,-0.08397003066656783,1.4211029662479921,-0.5023966694843781,-1.086586487466602,0.019871864265687718,-0.6342192735405214,-0.24029329531427543,-0.3710941852773667,0.1234239573228073,0.27822474270062764,0.3039647528659509,-0.05798197126028844,-0.4235539786397383,-0.1360020577956454,2.854945010826298,-0.24029329531427543,1.0687366974464951,-0.5814265778010619,-0.03201238316427893,-0.21419176492469524,2.806129116763043,-0.39731397995833206,-0.5814265778010619,-0.18810946914769616,-0.4235539786397383,-0.4235539786397383,-0.03201238316427893,0.5860117936562828,-0.6606479316905032,-0.47609517429475745,-0.03201238316427893,1.0181752334237035,8.366255129812147,0.32968786719872717,1.8703440739483437 | 3,246 |
Respirasome | 13 | 42 | 2.419311 | 0.01555 | Q9P0J0,Q13423,Q96CU9,O14949,P14406,O96000,Q9Y6M9,P00403,Q86Y39,Q6DKK2,P22695,Q9UDW1,O43676 | Localization | GO Cellular component | msigdb_gocc | 295,130,73,138,43,203,145,181,282,89,25,247,95 | 2606,1113,138,422,95,3143,1266,2841,1666,2394,3039,2766,2997,203,181,2564,2343,832,484,43,2961,2528,749,1228,25,3134,2410,2133,2782,1984,130,2787,1621,89,339,282,73,2513,295,247,2520,145 | -0.5550622157783601,0.04578676244131425,1.9200098581999967,0.6370836521056745,2.4140805364413698,-1.1134097681064297,-0.03201238316427893,-0.6870983502389405,-0.18810946914769616,-0.4498143273913549,-0.8728750171589886,-0.6342192735405214,-0.819682822993657,1.4211029662479921,1.5713097730015686,-0.5287189651896583,-0.4235539786397383,0.22669361755482975,0.5348766285518468,3.3650872278199344,-0.7931210294366591,-0.5023966694843781,0.27822474270062764,-0.006061144709344608,3.919014730047917,-1.086586487466602,-0.4498143273913549,-0.3448944504989137,-0.6342192735405214,-0.29255459388450233,2.0191969613257443,-0.6342192735405214,-0.1620462766525934,2.5859395556139195,0.8407522538471938,1.0687366974464951,2.806129116763043,-0.47609517429475745,1.0181752334237035,1.1948922097827732,-0.47609517429475745,1.8703440739483437 | 3,246 |
Protein import | 25 | 85 | 2.419215 | 0.015554 | O95071,Q15388,Q9Y5Y5,O00410,O60830,O96008,P50542,Q8N1F7,Q8TEX9,Q9NS69,Q9Y512,O15397,Q92973,Q13501,P52292,Q99595,Q7Z4Q2,O75312,O14925,O14737,P55060,P40855,P61970,Q9UKG1,P31749 | Processes and pathways | GO Biological process | msigdb_gobp | 505,259,261,502,11,509,270,401,144,21,157,527,429,427,44,50,56,187,334,212,344,227,365,499,363 | 502,2561,936,212,334,527,938,941,2719,11,187,2338,1739,1500,505,710,905,528,509,1385,1669,944,945,1225,1969,1579,1505,2772,2775,363,1327,2056,1594,1749,227,2575,1752,1398,270,44,1903,1753,344,1608,1756,365,1338,1757,1921,2477,2847,2359,427,1136,2682,259,3146,1859,1345,806,1291,2230,56,401,144,1300,429,778,2859,1633,50,2017,2917,1799,2246,1556,3092,21,2326,2517,499,2953,157,1436,261 | 0.5092850756510509,-0.5287189651896583,0.14926757041348834,1.3458212477032034,0.8407522538471938,0.4836774176196852,0.14926757041348834,0.14926757041348834,-0.6078122100368903,4.895169327756598,1.5212930700276128,-0.4235539786397383,-0.21419176492469524,-0.1360020577956454,0.5092850756510509,0.3039647528659509,0.1750936448097422,0.4836774176196852,0.5092850756510509,-0.08397003066656783,-0.18810946914769616,0.14926757041348834,0.14926757041348834,-0.006061144709344608,-0.29255459388450233,-0.1620462766525934,-0.1360020577956454,-0.6342192735405214,-0.6342192735405214,0.7644910395751178,-0.05798197126028844,-0.31871463345796447,-0.1620462766525934,-0.21419176492469524,1.2704182773309,-0.5287189651896583,-0.21419176492469524,-0.08397003066656783,1.0939960112015843,3.340892378532978,-0.2664141933665721,-0.21419176492469524,0.8153469194562949,-0.1620462766525934,-0.21419176492469524,0.7644910395751178,-0.05798197126028844,-0.21419176492469524,-0.2664141933665721,-0.47609517429475745,-0.6870983502389405,-0.4235539786397383,0.6370836521056745,0.04578676244131425,-0.5814265778010619,1.14447217515618,-1.1134097681064297,-0.24029329531427543,-0.05798197126028844,0.25246773267811196,-0.03201238316427893,-0.3710941852773667,3.195521831934781,0.6880929270902055,1.8703440739483437,-0.03201238316427893,0.6370836521056745,0.27822474270062764,-0.6870983502389405,-0.1620462766525934,3.2682504863299298,-0.29255459388450233,-0.7400651437154296,-0.21419176492469524,-0.3710941852773667,-0.1360020577956454,-0.9528376270712595,4.2300299284583565,-0.39731397995833206,-0.47609517429475745,0.5348766285518468,-0.7665818624827188,1.7459653822593797,-0.08397003066656783,1.14447217515618 | 3,246 |
Outer membrane | 18 | 90 | 2.418638 | 0.015579 | P09601,P57105,Q5HYI7,Q8N4H5,Q07820,Q8N2A8,Q8WY22,Q9NQZ5,P21796,Q9NS69,Q13505,O43169,Q99536,Q9HCL2,O75431,Q9Y512,Q99720,P45880 | Localization | GO Cellular component | msigdb_gocc | 98,229,135,75,169,47,176,149,53,21,23,120,183,58,248,157,62,31 | 578,935,3228,120,1267,2041,2119,248,1500,2265,2459,509,2723,2612,1968,98,2872,53,2411,2874,1035,2281,31,1453,533,582,2577,229,365,169,2292,23,1618,259,883,803,2487,135,960,1863,486,2306,2230,453,1707,2429,563,47,75,1350,1145,2159,2313,964,176,2589,2857,3185,1053,2166,1012,3147,183,2017,62,890,2702,2981,2757,1943,58,2105,149,21,2554,1107,3193,523,2106,392,598,524,672,738,3204,1111,1732,358,157,549 | 0.43241340517931676,0.14926757041348834,-2.069767972458231,2.118194303237033,-0.03201238316427893,-0.31871463345796447,-0.3448944504989137,1.1696891723387541,-0.1360020577956454,-0.39731397995833206,-0.47609517429475745,0.5092850756510509,-0.6078122100368903,-0.5550622157783601,-0.29255459388450233,2.3402615879978588,-0.713570697362591,3.219774416782617,-0.4498143273913549,-0.713570697362591,0.09756269387250471,-0.39731397995833206,3.7990028619728236,-0.10997668458835863,0.4836774176196852,0.43241340517931676,-0.5287189651896583,1.2704182773309,0.7644910395751178,1.646238301853119,-0.39731397995833206,4.062740258133748,-0.1620462766525934,1.14447217515618,0.2009022908471458,0.25246773267811196,-0.47609517429475745,1.9448246105356892,0.14926757041348834,-0.24029329531427543,0.5348766285518468,-0.39731397995833206,-0.3710941852773667,0.5860117936562828,-0.18810946914769616,-0.4498143273913549,0.4580535594777235,3.3166879953213755,2.757271750668178,-0.05798197126028844,0.04578676244131425,-0.3448944504989137,-0.39731397995833206,0.14926757041348834,1.6212749135794295,-0.5287189651896583,-0.6870983502389405,-1.3559712226120229,0.09756269387250471,-0.3448944504989137,0.1234239573228073,-1.1134097681064297,1.5713097730015686,-0.29255459388450233,3.0984136398458118,0.2009022908471458,-0.5814265778010619,-0.7931210294366591,-0.6078122100368903,-0.2664141933665721,3.195521831934781,-0.31871463345796447,1.845492931563142,4.2300299284583565,-0.5023966694843781,0.07168366704405241,-1.4373042480210472,0.5092850756510509,-0.31871463345796447,0.7135743175341883,0.43241340517931676,0.5092850756510509,0.355394188525345,0.3039647528659509,-1.5734207251531536,0.07168366704405241,-0.18810946914769616,0.7899265425128388,1.7459653822593797,0.4836774176196852 | 3,246 |
Aurka activation by tpx2 | 10 | 31 | 2.417262 | 0.015638 | P43034,Q15154,P41208,P04350,O94927,O95684,Q9H6D7,Q13561,P30153,O75935 | Processes and pathways | Reactome Pathways | msigdb_reactome | 128,411,34,510,297,19,151,471,435,125 | 623,1317,125,297,19,510,944,1270,945,1176,435,34,128,1985,878,799,534,714,1690,1342,471,2785,1003,2082,411,764,1785,690,814,151,2987 | 0.38108381849412826,-0.05798197126028844,2.0687191415996717,0.9928729317279787,4.3492703956282925,0.5092850756510509,0.14926757041348834,-0.03201238316427893,0.14926757041348834,0.019871864265687718,0.6115555906448871,3.7268890651643467,2.0439639548690964,-0.29255459388450233,0.2009022908471458,0.25246773267811196,0.4836774176196852,0.3039647528659509,-0.18810946914769616,-0.05798197126028844,0.5604521702536023,-0.6342192735405214,0.1234239573228073,-0.31871463345796447,0.6625960679420675,0.27822474270062764,-0.21419176492469524,0.32968786719872717,0.25246773267811196,1.7957538664939172,-0.7931210294366591 | 3,246 |
Recruitment of numa to mitotic centrosomes | 10 | 35 | 2.410283 | 0.01594 | P43034,Q15154,P41208,P04350,O94927,O95684,Q9H6D7,Q13561,P30153,O75935 | Processes and pathways | Reactome Pathways | msigdb_reactome | 128,411,34,510,297,19,151,471,435,125 | 1317,125,297,19,510,944,1270,945,1176,435,34,128,1985,878,799,534,714,1690,1342,471,1044,2785,1003,2082,2786,411,764,1785,690,1099,814,1015,646,2173,151 | -0.05798197126028844,2.0687191415996717,0.9928729317279787,4.3492703956282925,0.5092850756510509,0.14926757041348834,-0.03201238316427893,0.14926757041348834,0.019871864265687718,0.6115555906448871,3.7268890651643467,2.0439639548690964,-0.29255459388450233,0.2009022908471458,0.25246773267811196,0.4836774176196852,0.3039647528659509,-0.18810946914769616,-0.05798197126028844,0.5604521702536023,0.09756269387250471,-0.6342192735405214,0.1234239573228073,-0.31871463345796447,-0.6342192735405214,0.6625960679420675,0.27822474270062764,-0.21419176492469524,0.32968786719872717,0.07168366704405241,0.25246773267811196,0.1234239573228073,0.38108381849412826,-0.3448944504989137,1.7957538664939172 | 3,246 |
Glycosphingolipid metabolism | 7 | 17 | 2.404296 | 0.016204 | P07602,P16278,P10619,P04062,Q16739,Q13510,P17900 | Processes and pathways | Reactome Pathways | msigdb_reactome | 65,33,199,76,78,272,214 | 1264,706,76,370,2193,65,3105,199,2127,33,214,272,78,2242,2106,1727,598 | -0.03201238316427893,0.3039647528659509,2.732827412432188,0.739040326321,-0.3710941852773667,3.049800312599363,-1.0062644931084461,1.4461702390450293,-0.3448944504989137,3.7268890651643467,1.3458212477032034,1.0939960112015843,2.732827412432188,-0.3710941852773667,-0.31871463345796447,-0.18810946914769616,0.43241340517931676 | 3,246 |
Azurophil granule | 26 | 74 | 2.40349 | 0.016239 | O00462,P42785,O75629,P15586,Q9BRF8,P16278,Q9BTY2,Q9H7Z7,P10253,O00560,O00584,Q99536,O15260,P07602,Q9NZJ7,P10619,Q9NQX7,P17900,P53634,P61916,P78371,Q07065,Q8NF37,P15291,P27105,P06280 | Localization | GO Cellular component | msigdb_gocc | 503,7,139,530,159,33,570,432,298,551,552,183,63,65,598,199,211,214,352,105,366,235,491,362,238,370 | 2713,503,551,552,702,63,1072,706,2042,2956,745,139,1826,873,2723,630,370,2193,2195,1270,65,3105,1445,298,199,1743,791,2127,362,530,33,214,238,2843,2054,2207,7,1082,1842,2825,1844,1036,1333,352,1237,2064,1609,105,1690,366,3155,1992,235,999,2082,2088,2639,491,614,1867,1357,1940,183,1634,159,570,2550,3033,432,211,2178,598,1646,2449 | -0.6078122100368903,0.5092850756510509,0.4580535594777235,0.4580535594777235,0.3039647528659509,3.074111943417051,0.07168366704405241,0.3039647528659509,-0.31871463345796447,-0.7931210294366591,0.27822474270062764,1.9200098581999967,-0.24029329531427543,0.2009022908471458,-0.6078122100368903,0.38108381849412826,0.739040326321,-0.3710941852773667,-0.3710941852773667,-0.03201238316427893,3.049800312599363,-1.0062644931084461,-0.10997668458835863,0.9928729317279787,1.4461702390450293,-0.21419176492469524,0.25246773267811196,-0.3448944504989137,0.7644910395751178,0.4836774176196852,3.7268890651643467,1.3458212477032034,1.2200813591990216,-0.6870983502389405,-0.31871463345796447,-0.3710941852773667,5.248982947695327,0.07168366704405241,-0.24029329531427543,-0.6606479316905032,-0.24029329531427543,0.09756269387250471,-0.05798197126028844,0.7899265425128388,-0.006061144709344608,-0.31871463345796447,-0.1620462766525934,2.266341771441869,-0.18810946914769616,0.7644910395751178,-1.167131539845109,-0.29255459388450233,1.2452566916042276,0.1234239573228073,-0.31871463345796447,-0.31871463345796447,-0.5550622157783601,0.5348766285518468,0.40675685759510555,-0.24029329531427543,-0.05798197126028844,-0.2664141933665721,1.5713097730015686,-0.1620462766525934,1.7210524640385625,0.4580535594777235,-0.5023966694843781,-0.8462674242732842,0.6370836521056745,1.3709285366908623,-0.3448944504989137,0.43241340517931676,-0.1620462766525934,-0.4498143273913549 | 3,246 |
Serine hydrolase activity | 7 | 18 | 2.397723 | 0.016497 | P53634,P42785,P10619,Q16740,Q9H3G5,Q9HB40,O75976 | Functions | GO Molecular function | msigdb_gomf | 352,7,199,38,313,57,342 | 2522,1073,342,199,1582,1510,2967,7,2932,1753,352,1282,38,371,560,2089,313,57 | -0.5023966694843781,0.07168366704405241,0.8153469194562949,1.4461702390450293,-0.1620462766525934,-0.1360020577956454,-0.7931210294366591,5.248982947695327,-0.7665818624827188,-0.21419176492469524,0.7899265425128388,-0.03201238316427893,3.461771979995661,0.739040326321,0.4580535594777235,-0.31871463345796447,0.9422248046510306,3.195521831934781 | 3,246 |
Sphingolipid metabolism in senescence | 6 | 12 | 2.391647 | 0.016773 | P16278,P04062,Q16739,Q13510,Q96G23,Q06136 | Processes and pathways | WikiPathways | msigdb_wp | 33,76,78,272,113,345 | 741,76,2768,383,33,1509,2843,1035,345,272,78,113 | 0.27822474270062764,2.732827412432188,-0.6342192735405214,0.7135743175341883,3.7268890651643467,-0.1360020577956454,-0.6870983502389405,0.09756269387250471,0.8153469194562949,1.0939960112015843,2.732827412432188,2.2170052153908957 | 3,246 |
Ascites | 8 | 25 | 2.388225 | 0.01693 | P10644,O15118,Q14108,P61916,P04062,Q13510,Q92889,Q14739 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 222,131,4,105,76,272,316,126 | 131,3121,1377,1319,76,1445,222,2345,1972,3230,1398,2138,105,1189,1990,2290,996,272,4,126,1244,2156,316,322,1436 | 1.994418108265382,-1.059787988728998,-0.08397003066656783,-0.05798197126028844,2.732827412432188,-0.10997668458835863,1.2955661860369987,-0.4235539786397383,-0.29255459388450233,-2.1814737775608597,-0.08397003066656783,-0.3448944504989137,2.266341771441869,0.019871864265687718,-0.29255459388450233,-0.39731397995833206,0.1234239573228073,1.0939960112015843,5.4604731281181715,2.0687191415996717,-0.006061144709344608,-0.3448944504989137,0.91687882319615,0.8915181244165605,-0.08397003066656783 | 3,246 |
Establishment of protein localization to organelle | 46 | 183 | 2.383792 | 0.017135 | O95071,P55786,Q14108,Q9Y5Y5,Q15388,O00410,P46379,O60830,O96008,P50542,Q8N1F7,Q8TEX9,Q9NS69,P49257,P0DP25,Q9Y512,O15397,Q9P0J0,Q15070,Q15629,Q92973,Q13501,Q10713,P52292,Q99595,Q8N8Q8,Q7Z4Q2,O75312,Q9Y2T2,Q8N4H5,O14925,P50991,Q99523,O14737,P55060,P46934,Q9Y3D6,O43765,O00170,P40855,P61970,Q9UHB9,Q9UKG1,P78371,P31749,P20645 | Processes and pathways | GO Biological process | msigdb_gobp | 505,3,4,261,259,502,10,11,509,270,401,144,21,278,277,157,527,295,410,166,429,427,170,44,50,179,56,187,463,75,334,80,209,212,344,225,358,466,465,227,365,368,499,366,363,121 | 465,1659,502,2561,936,553,212,334,787,527,1073,938,706,466,941,2719,11,2868,1378,187,2190,2338,2043,1739,2523,1500,505,2265,710,2664,1502,905,528,509,1385,1669,944,945,1225,2403,1446,277,1969,1579,2197,791,1505,2772,1973,2872,1829,121,2775,874,1511,363,1327,2056,1683,1594,2618,1749,227,10,225,1397,278,1516,1126,2575,1752,1398,1517,270,1842,80,1454,1083,44,1903,582,1753,344,3,1608,2934,2902,1909,2068,1520,1756,365,1338,1757,1759,366,1921,2477,170,2847,2359,427,4,2581,1136,2682,1196,1137,410,259,166,3146,1859,883,1345,2487,560,806,3045,1347,2539,1291,2540,2230,56,1865,1543,401,75,179,144,1300,1628,1418,429,778,2859,1012,1794,209,1633,779,50,2017,644,593,1058,2701,2917,1799,857,3006,2803,893,2246,1556,3092,21,2326,1308,295,2838,1488,1647,648,368,2517,3077,2805,499,2953,933,1431,2520,463,1732,358,2865,157,699,1436,1223,261 | 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| 3,246 |
Protein transmembrane import into intracellular organelle | 7 | 14 | 2.37914 | 0.017353 | Q15388,Q9Y5Y5,O60830,O96008,P50542,O14925,Q99595 | Processes and pathways | GO Biological process | msigdb_gobp | 259,261,11,509,270,334,50 | 334,938,11,2338,1500,528,509,1969,270,259,1345,50,2246,261 | 0.8407522538471938,0.14926757041348834,4.895169327756598,-0.4235539786397383,-0.1360020577956454,0.4836774176196852,0.5092850756510509,-0.29255459388450233,1.0939960112015843,1.14447217515618,-0.05798197126028844,3.2682504863299298,-0.3710941852773667,1.14447217515618 | 3,246 |
Selective autophagy | 10 | 33 | 2.374846 | 0.017556 | P54619,Q15388,Q13501,P04350,P08670,Q8N4H5,P50542,Q8IWA4,Q9NS69,P21796 | Processes and pathways | Reactome Pathways | msigdb_reactome | 514,259,427,510,198,75,270,453,21,53 | 1496,1886,1500,2265,509,510,945,198,1579,1829,53,270,514,2064,635,714,841,1690,1342,427,1044,2082,259,453,75,1053,1208,2166,2696,646,2173,21,1024 | -0.1360020577956454,-0.2664141933665721,-0.1360020577956454,-0.39731397995833206,0.5092850756510509,0.5092850756510509,0.14926757041348834,1.4461702390450293,-0.1620462766525934,-0.24029329531427543,3.219774416782617,1.0939960112015843,0.5092850756510509,-0.31871463345796447,0.38108381849412826,0.3039647528659509,0.22669361755482975,-0.18810946914769616,-0.05798197126028844,0.6370836521056745,0.09756269387250471,-0.31871463345796447,1.14447217515618,0.5860117936562828,2.757271750668178,0.09756269387250471,0.019871864265687718,-0.3448944504989137,-0.5814265778010619,0.38108381849412826,-0.3448944504989137,4.2300299284583565,0.1234239573228073 | 3,246 |
Protease | 18 | 83 | 2.372143 | 0.017685 | P07858,P55786,Q9NZ08,P28072,Q8TCT8,Q16740,P42785,P10619,P53634,O95630,Q9H3G5,P42892,Q9UIQ6,Q7Z2K6,O75976,P28074,O75844,Q9HB40 | Functions | Protein Atlas Molecular function | protein_atlas_molecular_function | 153,3,35,184,287,38,7,199,352,361,313,54,119,26,342,224,190,57 | 1566,1315,2522,1073,1438,2043,190,342,1824,361,1388,153,1742,199,1322,1323,3056,184,224,3041,1510,2967,425,7,54,1898,2932,1399,3217,1037,1753,660,352,2901,3,2902,1282,3235,1093,2423,1196,38,371,560,923,807,2490,2307,26,1293,287,3231,2750,810,1356,1474,1419,1631,543,2240,473,1055,617,2696,733,644,816,313,1427,2176,1258,57,1363,2379,3232,1557,35,119,1430,1222,1069,1070,1654 | -0.1620462766525934,-0.05798197126028844,-0.5023966694843781,0.07168366704405241,-0.10997668458835863,-0.31871463345796447,1.4962652266439553,0.8153469194562949,-0.24029329531427543,0.7644910395751178,-0.08397003066656783,1.7708658304290625,-0.21419176492469524,1.4461702390450293,-0.05798197126028844,-0.05798197126028844,-0.899505788360606,1.5463078978712268,1.2955661860369987,-0.8728750171589886,-0.1360020577956454,-0.7931210294366591,0.6370836521056745,5.248982947695327,3.195521831934781,-0.2664141933665721,-0.7665818624827188,-0.08397003066656783,-1.8755094393685137,0.09756269387250471,-0.21419176492469524,0.355394188525345,0.7899265425128388,-0.7400651437154296,5.788310865118061,-0.7400651437154296,-0.03201238316427893,-2.5762000466031605,0.07168366704405241,-0.4498143273913549,0.019871864265687718,3.461771979995661,0.739040326321,0.4580535594777235,0.1750936448097422,0.25246773267811196,-0.47609517429475745,-0.39731397995833206,3.919014730047917,-0.03201238316427893,1.0434631299656707,-2.1814737775608597,-0.6078122100368903,0.25246773267811196,-0.05798197126028844,-0.10997668458835863,-0.08397003066656783,-0.1620462766525934,0.4836774176196852,-0.3710941852773667,0.5604521702536023,0.09756269387250471,0.40675685759510555,-0.5814265778010619,0.3039647528659509,0.38108381849412826,0.25246773267811196,0.9422248046510306,-0.08397003066656783,-0.3448944504989137,-0.006061144709344608,3.195521831934781,-0.05798197126028844,-0.4235539786397383,-2.2094772855618086,-0.1360020577956454,3.7028331681230524,2.1429143813660745,-0.08397003066656783,0.019871864265687718,0.09756269387250471,0.09756269387250471,-0.1620462766525934 | 3,246 |
Splenomegaly | 19 | 93 | 2.366019 | 0.017981 | P51798,O15118,Q14108,P33991,P28070,Q13510,P16278,Q9NZ08,Q10713,Q15392,P10253,Q15437,P07602,P04062,P21281,P54802,Q9NPE3,P61916,Q14739 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 251,131,4,8,142,272,33,35,170,46,298,177,65,76,337,217,226,105,126 | 2990,1659,1813,702,553,1663,131,1268,2868,2189,1119,2458,2998,2460,629,790,1385,76,630,2767,1669,2665,2400,2122,65,1445,298,2770,2404,2726,580,1390,1322,511,530,33,1972,2872,337,1032,2129,2204,142,1747,1510,363,8,2930,2533,3230,1452,950,2138,251,2210,1128,2063,217,3098,105,1039,557,1918,170,272,761,4,126,46,177,1288,1532,683,769,428,2231,811,2543,2097,642,2544,472,2500,1209,1012,1061,2701,3033,226,2028,35,598,3166 | -0.819682822993657,-0.18810946914769616,-0.24029329531427543,0.3039647528659509,0.4580535594777235,-0.18810946914769616,1.994418108265382,-0.03201238316427893,-0.713570697362591,-0.3710941852773667,0.04578676244131425,-0.47609517429475745,-0.819682822993657,-0.47609517429475745,0.38108381849412826,0.25246773267811196,-0.08397003066656783,2.732827412432188,0.38108381849412826,-0.6342192735405214,-0.18810946914769616,-0.5814265778010619,-0.4498143273913549,-0.3448944504989137,3.049800312599363,-0.10997668458835863,0.9928729317279787,-0.6342192735405214,-0.4498143273913549,-0.6078122100368903,0.43241340517931676,-0.08397003066656783,-0.05798197126028844,0.5092850756510509,0.4836774176196852,3.7268890651643467,-0.29255459388450233,-0.713570697362591,0.8407522538471938,0.09756269387250471,-0.3448944504989137,-0.3710941852773667,1.8951830310030808,-0.21419176492469524,-0.1360020577956454,0.7644910395751178,5.225447598312084,-0.7665818624827188,-0.5023966694843781,-2.1814737775608597,-0.10997668458835863,0.14926757041348834,-0.3448944504989137,1.1696891723387541,-0.3710941852773667,0.04578676244131425,-0.31871463345796447,1.3207004867153997,-0.9795390827213797,2.266341771441869,0.09756269387250471,0.4580535594777235,-0.2664141933665721,1.646238301853119,1.0939960112015843,0.27822474270062764,5.4604731281181715,2.0687191415996717,3.3166879953213755,1.5962987576738683,-0.03201238316427893,-0.1360020577956454,0.32968786719872717,0.27822474270062764,0.6370836521056745,-0.3710941852773667,0.25246773267811196,-0.5023966694843781,-0.31871463345796447,0.38108381849412826,-0.5023966694843781,0.5604521702536023,-0.47609517429475745,0.019871864265687718,0.1234239573228073,0.09756269387250471,-0.5814265778010619,-0.8462674242732842,1.2955661860369987,-0.29255459388450233,3.7028331681230524,0.43241340517931676,-1.2209550696577467 | 3,246 |
Cell activation | 42 | 134 | 2.365461 | 0.018008 | P24390,P35579,P46379,P14174,Q08722,Q9UNH7,Q5RKV6,Q8WXW3,Q96FZ2,P62942,Q96IZ0,Q07954,P42574,Q9NRA0,P17812,Q5HYI8,O14617,Q9HCL2,Q9UQ84,P55327,P13051,P04062,Q96L92,P11274,P30825,Q92614,Q9NQT8,O96028,Q92542,Q9BY67,P09601,P10644,P53634,P01130,Q99584,P31749,Q9BXW9,Q9Y4B6,Q9NUQ9,Q9NQT5,P78318,P00813 | Processes and pathways | GO Biological process | msigdb_gobp | 2,512,10,511,537,674,666,283,543,286,292,409,425,571,299,178,553,58,59,556,194,76,208,580,215,340,349,213,614,219,98,222,352,351,496,363,240,649,246,378,252,629 | 2713,2389,1659,1314,553,2390,1114,3132,1665,1737,943,1169,906,213,2460,1966,629,351,1076,76,1575,711,1669,747,1172,2527,1269,2402,1174,98,2769,222,1969,580,791,2268,1122,1892,194,511,299,1273,2775,1275,2,1231,215,363,1396,1748,1976,875,512,2207,835,1749,2572,1035,425,876,10,1081,2731,1185,2352,1036,1903,1603,660,352,556,2070,2215,286,252,1458,3211,1850,879,2938,1191,409,2477,537,1240,1995,2581,1004,2000,1927,3180,2850,178,2302,666,2851,1538,2742,2154,1251,283,851,614,2012,340,1207,1713,1420,543,292,2500,2887,208,732,496,2017,2981,240,219,2550,58,378,349,571,2026,246,901,2114,674,59,2865,2330,649,1884 | -0.6078122100368903,-0.4498143273913549,-0.18810946914769616,-0.05798197126028844,0.4580535594777235,-0.4498143273913549,0.04578676244131425,-1.086586487466602,-0.18810946914769616,-0.21419176492469524,0.14926757041348834,0.019871864265687718,0.1750936448097422,1.3458212477032034,-0.47609517429475745,-0.29255459388450233,0.38108381849412826,0.7899265425128388,0.07168366704405241,2.732827412432188,-0.1620462766525934,0.3039647528659509,-0.18810946914769616,0.27822474270062764,0.019871864265687718,-0.5023966694843781,-0.03201238316427893,-0.4498143273913549,0.019871864265687718,2.3402615879978588,-0.6342192735405214,1.2955661860369987,-0.29255459388450233,0.43241340517931676,0.25246773267811196,-0.39731397995833206,0.04578676244131425,-0.2664141933665721,1.4712243043141844,0.5092850756510509,0.9928729317279787,-0.03201238316427893,-0.6342192735405214,-0.03201238316427893,7.063640679323355,-0.006061144709344608,1.3458212477032034,0.7644910395751178,-0.08397003066656783,-0.21419176492469524,-0.29255459388450233,0.2009022908471458,0.5092850756510509,-0.3710941852773667,0.22669361755482975,-0.21419176492469524,-0.5287189651896583,0.09756269387250471,0.6370836521056745,0.2009022908471458,4.989685390213567,0.07168366704405241,-0.6078122100368903,0.019871864265687718,-0.4235539786397383,0.09756269387250471,-0.2664141933665721,-0.1620462766525934,0.355394188525345,0.7899265425128388,0.4580535594777235,-0.31871463345796447,-0.3710941852773667,1.0434631299656707,1.1696891723387541,-0.10997668458835863,-1.6828394367657349,-0.24029329531427543,0.2009022908471458,-0.7665818624827188,0.019871864265687718,0.6625960679420675,-0.47609517429475745,0.4836774176196852,-0.006061144709344608,-0.29255459388450233,-0.5287189651896583,0.1234239573228073,-0.29255459388450233,-0.2664141933665721,-1.3289147692140848,-0.6870983502389405,1.5962987576738683,-0.39731397995833206,0.355394188525345,-0.6870983502389405,-0.1360020577956454,-0.6078122100368903,-0.3448944504989137,-0.006061144709344608,1.0687366974464951,0.22669361755482975,0.40675685759510555,-0.29255459388450233,0.8407522538471938,0.019871864265687718,-0.18810946914769616,-0.08397003066656783,0.4836774176196852,1.0181752334237035,-0.47609517429475745,-0.713570697362591,1.3960224207311585,0.3039647528659509,0.5348766285518468,-0.29255459388450233,-0.7931210294366591,1.2200813591990216,1.3207004867153997,-0.5023966694843781,3.195521831934781,0.739040326321,0.8153469194562949,0.4580535594777235,-0.29255459388450233,1.1948922097827732,0.2009022908471458,-0.31871463345796447,0.355394188525345,3.171259498599697,-0.6870983502389405,-0.39731397995833206,0.38108381849412826,-0.24029329531427543 | 3,246 |
Cardiac muscle contraction | 7 | 20 | 2.363131 | 0.018121 | P09493,O14949,P14406,P00403,Q9UDW1,P67936,P22695 | Processes and pathways | KEGG Pathways | msigdb_kegg | 160,138,43,181,247,280,25 | 1113,138,181,1387,1320,336,2564,160,2343,832,484,43,2961,1031,749,25,2133,2622,280,247 | 0.04578676244131425,1.9200098581999967,1.5713097730015686,-0.08397003066656783,-0.05798197126028844,0.8407522538471938,-0.5287189651896583,1.6961270173061391,-0.4235539786397383,0.22669361755482975,0.5348766285518468,3.3650872278199344,-0.7931210294366591,0.09756269387250471,0.27822474270062764,3.919014730047917,-0.3448944504989137,-0.5550622157783601,1.0687366974464951,1.1948922097827732 | 3,246 |
Establishment of protein localization to mitochondrial membrane | 6 | 16 | 2.356195 | 0.018463 | Q9P0J0,Q8N8Q8,Q9NS69,O14737,P0DP25,Q9Y512 | Processes and pathways | GO Biological process | msigdb_gobp | 295,179,21,212,277,157 | 1659,212,1500,945,277,874,1327,410,2487,179,1628,21,295,2520,157,699 | -0.18810946914769616,1.3458212477032034,-0.1360020577956454,0.14926757041348834,1.0687366974464951,0.2009022908471458,-0.05798197126028844,0.6625960679420675,-0.47609517429475745,1.5962987576738683,-0.1620462766525934,4.2300299284583565,1.0181752334237035,-0.47609517429475745,1.7459653822593797,0.32968786719872717 | 3,246 |
Sterol metabolic process | 12 | 38 | 2.354621 | 0.018542 | O15118,P49748,P01130,O94905,P61916,Q9BQE5,P04062,Q15392,Q16850,Q8WTV0,Q14739,P48449 | Processes and pathways | GO Biological process | msigdb_gobp | 131,318,351,249,105,12,76,46,175,29,126,191 | 131,1224,249,2723,351,76,1172,1390,1175,1272,2569,2873,1979,3230,657,191,318,1333,105,2141,3161,1918,2848,1617,126,2975,3099,2425,46,2684,175,2906,372,29,12,2442,672,2603 | 1.994418108265382,-0.006061144709344608,1.1696891723387541,-0.6078122100368903,0.7899265425128388,2.732827412432188,0.019871864265687718,-0.08397003066656783,0.019871864265687718,-0.03201238316427893,-0.5287189651896583,-0.713570697362591,-0.29255459388450233,-2.1814737775608597,0.355394188525345,1.4962652266439553,0.8915181244165605,-0.05798197126028844,2.266341771441869,-0.3448944504989137,-1.19403047232757,-0.2664141933665721,-0.6870983502389405,-0.1620462766525934,2.0687191415996717,-0.7931210294366591,-0.9795390827213797,-0.4498143273913549,3.3166879953213755,-0.5814265778010619,1.6212749135794295,-0.7400651437154296,0.739040326321,3.8470341251685394,4.7768512995189685,-0.4498143273913549,0.355394188525345,-0.5287189651896583 | 3,246 |
Abnormal oral mucosa morphology | 12 | 59 | 2.35143 | 0.018701 | P16278,P10644,Q9NZ08,Q14108,Q96JJ3,P04062,Q15392,P21281,O75431,P49257,Q14739,Q9NPE3 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 33,222,35,4,321,76,46,337,248,278,126,226 | 1657,1659,702,2718,2868,2189,248,2998,790,76,2122,1445,222,3154,33,1745,337,2055,1749,3083,278,1452,1398,352,1909,2624,1458,1614,1761,1918,3085,1132,1616,761,4,126,2786,681,1618,46,2223,768,2538,1348,1540,2586,1207,1474,321,2701,226,2028,35,672,2654,1651,2386,2559,786 | -0.18810946914769616,-0.18810946914769616,0.3039647528659509,-0.6078122100368903,-0.713570697362591,-0.3710941852773667,1.1696891723387541,-0.819682822993657,0.25246773267811196,2.732827412432188,-0.3448944504989137,-0.10997668458835863,1.2955661860369987,-1.167131539845109,3.7268890651643467,-0.21419176492469524,0.8407522538471938,-0.31871463345796447,-0.21419176492469524,-0.9528376270712595,1.0687366974464951,-0.10997668458835863,-0.08397003066656783,0.7899265425128388,-0.2664141933665721,-0.5550622157783601,-0.10997668458835863,-0.1620462766525934,-0.21419176492469524,-0.2664141933665721,-0.9528376270712595,0.04578676244131425,-0.1620462766525934,0.27822474270062764,5.4604731281181715,2.0687191415996717,-0.6342192735405214,0.32968786719872717,-0.1620462766525934,3.3166879953213755,-0.3710941852773667,0.27822474270062764,-0.5023966694843781,-0.05798197126028844,-0.1360020577956454,-0.5287189651896583,0.019871864265687718,-0.10997668458835863,0.8915181244165605,-0.5814265778010619,1.2955661860369987,-0.29255459388450233,3.7028331681230524,0.355394188525345,-0.5550622157783601,-0.1620462766525934,-0.4235539786397383,-0.5023966694843781,0.27822474270062764 | 3,246 |
Secondary alcohol metabolic process | 12 | 43 | 2.350116 | 0.018768 | O15118,P49748,P01130,O94905,P61916,Q9BQE5,P04062,Q15392,Q16850,Q8WTV0,Q14739,P48449 | Processes and pathways | GO Biological process | msigdb_gobp | 131,318,351,249,105,12,76,46,175,29,126,191 | 131,2337,1224,2957,249,2723,351,76,1172,1390,1175,1272,2569,2873,1979,657,191,3022,318,2621,2285,1333,105,2141,3161,1918,2848,1617,126,2975,3099,2425,46,2684,175,2906,372,29,2644,12,2442,672,2603 | 1.994418108265382,-0.4235539786397383,-0.006061144709344608,-0.7931210294366591,1.1696891723387541,-0.6078122100368903,0.7899265425128388,2.732827412432188,0.019871864265687718,-0.08397003066656783,0.019871864265687718,-0.03201238316427893,-0.5287189651896583,-0.713570697362591,-0.29255459388450233,0.355394188525345,1.4962652266439553,-0.8462674242732842,0.8915181244165605,-0.5550622157783601,-0.39731397995833206,-0.05798197126028844,2.266341771441869,-0.3448944504989137,-1.19403047232757,-0.2664141933665721,-0.6870983502389405,-0.1620462766525934,2.0687191415996717,-0.7931210294366591,-0.9795390827213797,-0.4498143273913549,3.3166879953213755,-0.5814265778010619,1.6212749135794295,-0.7400651437154296,0.739040326321,3.8470341251685394,-0.5550622157783601,4.7768512995189685,-0.4498143273913549,0.355394188525345,-0.5287189651896583 | 3,246 |
Cis golgi network | 6 | 16 | 2.348316 | 0.018859 | P24390,O43617,Q9UNK9,Q9NPR9,Q96JB2,O00461 | Localization | GO Cellular component | msigdb_gocc | 2,446,480,420,347,93 | 93,446,2,1590,796,843,664,492,2095,851,347,1209,814,420,480,863 | 2.4632377586710623,0.5860117936562828,7.063640679323355,-0.1620462766525934,0.25246773267811196,0.22669361755482975,0.355394188525345,0.5348766285518468,-0.31871463345796447,0.22669361755482975,0.8153469194562949,0.019871864265687718,0.25246773267811196,0.6625960679420675,0.5604521702536023,0.22669361755482975 | 3,246 |
Inorganic molecular entity transmembrane transporter activity | 16 | 71 | 2.346544 | 0.018948 | P51798,Q13423,P00846,Q96ES6,O15439,Q9UBX3,Q9HD20,P21281,O75964,Q7KZN9,P21796,P00403,Q93050,Q9Y487,Q9UDW1,P45880 | Functions | GO Molecular function | msigdb_gomf | 251,130,101,173,296,143,51,337,210,339,53,181,85,122,247,31 | 1314,2892,1113,296,706,2811,210,1501,181,101,1387,1320,2527,830,2195,2048,2049,2564,2769,832,1391,484,1031,948,749,337,2346,53,1229,1394,2133,1448,1328,1276,31,3061,992,251,1084,2783,952,2903,1520,1991,3112,1404,130,3026,3219,339,1251,1351,1868,85,173,2502,644,390,3033,1426,2323,2918,51,1154,143,247,1730,1651,1111,122,2560 | -0.05798197126028844,-0.7400651437154296,0.04578676244131425,0.9928729317279787,0.3039647528659509,-0.6606479316905032,1.3709285366908623,-0.1360020577956454,1.5713097730015686,2.290992997439851,-0.08397003066656783,-0.05798197126028844,-0.5023966694843781,0.22669361755482975,-0.3710941852773667,-0.31871463345796447,-0.31871463345796447,-0.5287189651896583,-0.6342192735405214,0.22669361755482975,-0.08397003066656783,0.5348766285518468,0.09756269387250471,0.14926757041348834,0.27822474270062764,0.8407522538471938,-0.4235539786397383,3.219774416782617,-0.006061144709344608,-0.08397003066656783,-0.3448944504989137,-0.10997668458835863,-0.05798197126028844,-0.03201238316427893,3.7990028619728236,-0.899505788360606,0.1234239573228073,1.1696891723387541,0.07168366704405241,-0.6342192735405214,0.14926757041348834,-0.7400651437154296,-0.1360020577956454,-0.29255459388450233,-1.0330140600804507,-0.08397003066656783,2.0191969613257443,-0.8462674242732842,-1.8755094393685137,0.8407522538471938,-0.006061144709344608,-0.05798197126028844,-0.24029329531427543,2.634944712077862,1.646238301853119,-0.47609517429475745,0.38108381849412826,0.7135743175341883,-0.8462674242732842,-0.08397003066656783,-0.39731397995833206,-0.7400651437154296,3.2682504863299298,0.04578676244131425,1.8951830310030808,1.1948922097827732,-0.18810946914769616,-0.1620462766525934,0.07168366704405241,2.118194303237033,-0.5023966694843781 | 3,246 |
Pink1 prkn mediated mitophagy | 6 | 10 | 2.338259 | 0.019374 | Q15388,Q13501,Q8N4H5,Q8IWA4,P21796,Q9NS69 | Processes and pathways | Reactome Pathways | msigdb_reactome | 259,427,75,453,53,21 | 1500,2265,509,53,427,259,453,75,1053,21 | -0.1360020577956454,-0.39731397995833206,0.5092850756510509,3.219774416782617,0.6370836521056745,1.14447217515618,0.5860117936562828,2.757271750668178,0.09756269387250471,4.2300299284583565 | 3,246 |
Transport vesicle | 29 | 95 | 2.336721 | 0.019454 | P24390,Q15334,O76024,O43760,Q9Y6B6,P11717,Q9BT78,O60499,P49257,P0DP25,Q92572,P35606,Q15437,Q9Y3B3,P10321,O15260,P50897,Q9NR31,Q99523,Q92542,O00461,Q7L0J3,Q8TBA6,O95487,Q9UBV8,Q96A57,P20645,Q15363,O15126 | Localization | GO Cellular component | msigdb_gocc | 2,386,382,262,548,397,274,395,278,277,415,300,177,576,434,63,66,596,209,614,93,96,492,350,380,520,121,638,624 | 935,93,703,1162,624,63,1072,978,1665,262,1819,395,1886,1440,3133,1379,382,2525,1964,350,1826,2047,790,711,1172,1504,2342,277,434,791,397,948,1830,1508,1177,121,2,3057,2053,300,1276,1331,278,796,66,1454,2416,2417,992,1036,2286,2062,2210,2212,2067,2068,1335,2903,2071,1910,1688,1522,1043,3024,2535,2220,1197,665,386,638,763,177,96,1250,492,614,415,1356,520,209,274,1017,858,2104,1154,596,1068,380,2517,1262,2116,576,1372,548,824 | 0.14926757041348834,2.4632377586710623,0.3039647528659509,0.019871864265687718,0.38108381849412826,3.074111943417051,0.07168366704405241,0.1234239573228073,-0.18810946914769616,1.119241145820181,-0.24029329531427543,0.6880929270902055,-0.2664141933665721,-0.10997668458835863,-1.086586487466602,-0.08397003066656783,0.7135743175341883,-0.5023966694843781,-0.29255459388450233,0.7899265425128388,-0.24029329531427543,-0.31871463345796447,0.25246773267811196,0.3039647528659509,0.019871864265687718,-0.1360020577956454,-0.4235539786397383,1.0687366974464951,0.6115555906448871,0.25246773267811196,0.6880929270902055,0.14926757041348834,-0.24029329531427543,-0.1360020577956454,0.019871864265687718,2.118194303237033,7.063640679323355,-0.899505788360606,-0.31871463345796447,0.9928729317279787,-0.03201238316427893,-0.05798197126028844,1.0687366974464951,0.25246773267811196,2.8793375078697796,-0.10997668458835863,-0.4498143273913549,-0.4498143273913549,0.1234239573228073,0.09756269387250471,-0.39731397995833206,-0.31871463345796447,-0.3710941852773667,-0.3710941852773667,-0.31871463345796447,-0.31871463345796447,-0.05798197126028844,-0.7400651437154296,-0.31871463345796447,-0.2664141933665721,-0.18810946914769616,-0.1360020577956454,0.09756269387250471,-0.8462674242732842,-0.5023966694843781,-0.3710941852773667,0.019871864265687718,0.355394188525345,0.7135743175341883,0.38108381849412826,0.27822474270062764,1.5962987576738683,2.389485348920194,-0.006061144709344608,0.5348766285518468,0.40675685759510555,0.6625960679420675,-0.05798197126028844,0.5092850756510509,1.3960224207311585,1.0939960112015843,0.1234239573228073,0.22669361755482975,-0.31871463345796447,0.04578676244131425,0.43241340517931676,0.09756269387250471,0.739040326321,-0.47609517429475745,-0.006061144709344608,-0.31871463345796447,0.4580535594777235,-0.05798197126028844,0.4836774176196852,0.25246773267811196 | 3,246 |
Abc transporter disorders | 11 | 43 | 2.33547 | 0.019519 | P20618,P49721,Q9GZP9,Q9UL46,P28070,P60900,O00231,P28072,Q9BUN8,P28074,O94905 | Processes and pathways | Reactome Pathways | msigdb_reactome | 290,5,268,406,142,114,304,184,417,224,249 | 304,3054,1315,1959,742,1224,654,249,1325,290,1230,1179,1832,2203,1589,142,184,224,2730,2619,1515,676,5,1983,1847,2064,114,408,840,1130,2355,758,957,585,1698,1791,617,1940,417,268,573,406,2557 | 0.9675561480174244,-0.899505788360606,-0.05798197126028844,-0.29255459388450233,0.27822474270062764,-0.006061144709344608,0.355394188525345,1.1696891723387541,-0.05798197126028844,1.0181752334237035,-0.006061144709344608,0.019871864265687718,-0.24029329531427543,-0.3710941852773667,-0.1620462766525934,1.8951830310030808,1.5463078978712268,1.2955661860369987,-0.6078122100368903,-0.5550622157783601,-0.1360020577956454,0.32968786719872717,5.413525936075921,-0.29255459388450233,-0.24029329531427543,-0.31871463345796447,2.167622859137434,0.6625960679420675,0.22669361755482975,0.04578676244131425,-0.4235539786397383,0.27822474270062764,0.14926757041348834,0.43241340517931676,-0.18810946914769616,-0.21419176492469524,0.40675685759510555,-0.2664141933665721,0.6625960679420675,1.119241145820181,0.4580535594777235,0.6880929270902055,-0.5023966694843781 | 3,246 |
Defective cftr causes cystic fibrosis | 11 | 43 | 2.33547 | 0.019519 | P20618,P49721,Q9GZP9,Q9UL46,P28070,P60900,O00231,P28072,Q9BUN8,P28074,O94905 | Processes and pathways | Reactome Pathways | msigdb_reactome | 290,5,268,406,142,114,304,184,417,224,249 | 304,3054,1315,1959,742,1224,654,249,1325,290,1230,1179,1832,2203,1589,142,184,224,2730,2619,1515,676,5,1983,1847,2064,114,408,840,1130,2355,758,957,585,1698,1791,617,1940,417,268,573,406,2557 | 0.9675561480174244,-0.899505788360606,-0.05798197126028844,-0.29255459388450233,0.27822474270062764,-0.006061144709344608,0.355394188525345,1.1696891723387541,-0.05798197126028844,1.0181752334237035,-0.006061144709344608,0.019871864265687718,-0.24029329531427543,-0.3710941852773667,-0.1620462766525934,1.8951830310030808,1.5463078978712268,1.2955661860369987,-0.6078122100368903,-0.5550622157783601,-0.1360020577956454,0.32968786719872717,5.413525936075921,-0.29255459388450233,-0.24029329531427543,-0.31871463345796447,2.167622859137434,0.6625960679420675,0.22669361755482975,0.04578676244131425,-0.4235539786397383,0.27822474270062764,0.14926757041348834,0.43241340517931676,-0.18810946914769616,-0.21419176492469524,0.40675685759510555,-0.2664141933665721,0.6625960679420675,1.119241145820181,0.4580535594777235,0.6880929270902055,-0.5023966694843781 | 3,246 |
Mitophagy | 6 | 13 | 2.327944 | 0.019915 | Q15388,Q13501,Q8N4H5,Q8IWA4,Q9NS69,P21796 | Processes and pathways | Reactome Pathways | msigdb_reactome | 259,427,75,453,21,53 | 1500,2265,509,1829,53,841,427,259,453,75,1053,2166,21 | -0.1360020577956454,-0.39731397995833206,0.5092850756510509,-0.24029329531427543,3.219774416782617,0.22669361755482975,0.6370836521056745,1.14447217515618,0.5860117936562828,2.757271750668178,0.09756269387250471,-0.3448944504989137,4.2300299284583565 | 3,246 |
Intra golgi and retrograde golgi to er traffic | 22 | 94 | 2.325153 | 0.020064 | P43034,P24390,P04350,Q9UJW0,P11717,O60499,P35606,Q9Y3B3,O15260,P84085,Q9NQT8,P18085,Q96JB2,Q13561,P40616,Q13439,O00461,Q8TBA6,Q9P2W9,P20645,Q8TD16,O75935 | Processes and pathways | Reactome Pathways | msigdb_reactome | 128,2,510,405,397,395,300,576,63,72,349,88,347,471,343,470,93,492,242,121,519,125 | 2038,93,703,63,978,1496,2040,1819,395,1886,1379,125,1319,1963,873,510,397,88,1177,121,2,949,300,343,128,1980,2282,1330,1331,796,2416,912,1904,2286,2062,1186,878,2071,1688,714,1690,1339,1039,72,1761,1087,1341,956,1132,1765,1043,1342,470,471,1044,1003,2082,2974,1137,558,638,847,769,1543,2946,1049,2910,492,519,851,1208,347,2694,2697,1795,646,2173,1017,2593,1063,1018,858,3006,1876,349,2178,1158,242,1068,405,576,1022,1372,1024 | -0.31871463345796447,2.4632377586710623,0.3039647528659509,3.074111943417051,0.1234239573228073,-0.1360020577956454,-0.31871463345796447,-0.24029329531427543,0.6880929270902055,-0.2664141933665721,-0.08397003066656783,2.0687191415996717,-0.05798197126028844,-0.29255459388450233,0.2009022908471458,0.5092850756510509,0.6880929270902055,2.5859395556139195,0.019871864265687718,2.118194303237033,7.063640679323355,0.14926757041348834,0.9928729317279787,0.8153469194562949,2.0439639548690964,-0.29255459388450233,-0.39731397995833206,-0.05798197126028844,-0.05798197126028844,0.25246773267811196,-0.4498143273913549,0.1750936448097422,-0.2664141933665721,-0.39731397995833206,-0.31871463345796447,0.019871864265687718,0.2009022908471458,-0.31871463345796447,-0.18810946914769616,0.3039647528659509,-0.18810946914769616,-0.05798197126028844,0.09756269387250471,2.806129116763043,-0.21419176492469524,0.07168366704405241,-0.05798197126028844,0.14926757041348834,0.04578676244131425,-0.21419176492469524,0.09756269387250471,-0.05798197126028844,0.5604521702536023,0.5604521702536023,0.09756269387250471,0.1234239573228073,-0.31871463345796447,-0.7931210294366591,0.04578676244131425,0.4580535594777235,0.38108381849412826,0.22669361755482975,0.27822474270062764,-0.1360020577956454,-0.7665818624827188,0.09756269387250471,-0.7400651437154296,0.5348766285518468,0.5092850756510509,0.22669361755482975,0.019871864265687718,0.8153469194562949,-0.5814265778010619,-0.5814265778010619,-0.21419176492469524,0.38108381849412826,-0.3448944504989137,0.1234239573228073,-0.5287189651896583,0.09756269387250471,0.1234239573228073,0.22669361755482975,-0.819682822993657,-0.24029329531427543,0.8153469194562949,-0.3448944504989137,0.04578676244131425,1.2200813591990216,0.09756269387250471,0.6880929270902055,0.4580535594777235,0.1234239573228073,-0.05798197126028844,0.1234239573228073 | 3,246 |
Modified amino acid binding | 8 | 25 | 2.324757 | 0.020085 | Q14108,Q9H7Z7,O43813,Q9UKG1,P41440,P00374,Q08431,Q8WTV0 | Functions | GO Molecular function | msigdb_gomf | 4,432,325,499,108,152,314,29 | 325,1075,152,1386,2195,2048,1174,1579,2774,2129,1181,108,1451,1452,513,1921,314,4,29,1057,1634,2948,432,499,2330 | 0.8661426282602883,0.07168366704405241,1.7708658304290625,-0.08397003066656783,-0.3710941852773667,-0.31871463345796447,0.019871864265687718,-0.1620462766525934,-0.6342192735405214,-0.3448944504989137,0.019871864265687718,2.2416791937316303,-0.10997668458835863,-0.10997668458835863,0.5092850756510509,-0.2664141933665721,0.91687882319615,5.4604731281181715,3.8470341251685394,0.09756269387250471,-0.1620462766525934,-0.7665818624827188,0.6370836521056745,0.5348766285518468,-0.39731397995833206 | 3,246 |
T cell activation | 13 | 60 | 2.307484 | 0.021028 | Q96IZ0,P24390,P10644,P04062,P17812,Q9BXW9,Q5HYI8,P30825,Q9NQT8,Q9NUQ9,Q9HCL2,Q9BY67,P62942 | Processes and pathways | GO Biological process | msigdb_gobp | 292,2,222,76,299,240,178,215,349,246,58,219,286 | 1659,553,3132,1169,906,2460,629,1076,76,1575,711,1669,2402,1174,2769,222,1969,299,1275,2,1231,215,363,1396,1748,875,512,2207,1749,2572,1035,425,1185,2352,2070,2215,286,1458,3211,1850,1191,2477,537,2581,1004,178,1538,2742,614,2012,1207,1713,292,2500,240,219,58,349,246,901 | -0.18810946914769616,0.4580535594777235,-1.086586487466602,0.019871864265687718,0.1750936448097422,-0.47609517429475745,0.38108381849412826,0.07168366704405241,2.732827412432188,-0.1620462766525934,0.3039647528659509,-0.18810946914769616,-0.4498143273913549,0.019871864265687718,-0.6342192735405214,1.2955661860369987,-0.29255459388450233,0.9928729317279787,-0.03201238316427893,7.063640679323355,-0.006061144709344608,1.3458212477032034,0.7644910395751178,-0.08397003066656783,-0.21419176492469524,0.2009022908471458,0.5092850756510509,-0.3710941852773667,-0.21419176492469524,-0.5287189651896583,0.09756269387250471,0.6370836521056745,0.019871864265687718,-0.4235539786397383,-0.31871463345796447,-0.3710941852773667,1.0434631299656707,-0.10997668458835863,-1.6828394367657349,-0.24029329531427543,0.019871864265687718,-0.47609517429475745,0.4836774176196852,-0.5287189651896583,0.1234239573228073,1.5962987576738683,-0.1360020577956454,-0.6078122100368903,0.40675685759510555,-0.29255459388450233,0.019871864265687718,-0.18810946914769616,1.0181752334237035,-0.47609517429475745,1.2200813591990216,1.3207004867153997,3.195521831934781,0.8153469194562949,1.1948922097827732,0.2009022908471458 | 3,246 |
Vacuole organization | 7 | 50 | 2.305704 | 0.021127 | P11117,P50897,Q14108,P04062,O75503,P54802,Q8N511 | Processes and pathways | GO Biological process | msigdb_gobp | 223,66,4,76,82,217,188 | 1659,2522,1378,1379,82,2265,905,76,2195,3105,298,223,1031,1508,1035,950,66,1454,217,1907,1335,1688,4,1137,665,2088,1347,3156,1250,188,771,1354,2095,2544,854,616,858,1483,3006,2803,1154,1877,971,2030,933,821,903,1369,1732,1069 | -0.18810946914769616,-0.5023966694843781,-0.08397003066656783,-0.08397003066656783,2.634944712077862,-0.39731397995833206,0.1750936448097422,2.732827412432188,-0.3710941852773667,-1.0062644931084461,0.9928729317279787,1.2955661860369987,0.09756269387250471,-0.1360020577956454,0.09756269387250471,0.14926757041348834,2.8793375078697796,-0.10997668458835863,1.3207004867153997,-0.2664141933665721,-0.05798197126028844,-0.18810946914769616,5.4604731281181715,0.04578676244131425,0.355394188525345,-0.31871463345796447,-0.05798197126028844,-1.167131539845109,-0.006061144709344608,1.5212930700276128,0.27822474270062764,-0.05798197126028844,-0.31871463345796447,-0.5023966694843781,0.22669361755482975,0.40675685759510555,0.22669361755482975,-0.10997668458835863,-0.819682822993657,-0.6342192735405214,0.04578676244131425,-0.24029329531427543,0.14926757041348834,-0.29255459388450233,0.1750936448097422,0.25246773267811196,0.2009022908471458,-0.05798197126028844,-0.18810946914769616,0.09756269387250471 | 3,246 |
Regulation of pten stability and activity | 11 | 45 | 2.301556 | 0.02136 | P31751,P20618,P49721,Q9UL46,P28070,P31749,P60900,O00231,P28072,P28074,P46934 | Processes and pathways | Reactome Pathways | msigdb_reactome | 195,290,5,406,142,363,114,304,184,224,225 | 304,3054,1315,1959,742,654,1325,1829,290,1230,1179,1832,2203,1589,142,184,224,363,195,2730,2619,225,1515,676,5,1983,1847,114,408,840,1130,2355,841,557,758,957,585,1698,1791,617,1940,406,2328,2557,1652 | 0.9675561480174244,-0.899505788360606,-0.05798197126028844,-0.29255459388450233,0.27822474270062764,0.355394188525345,-0.05798197126028844,-0.24029329531427543,1.0181752334237035,-0.006061144709344608,0.019871864265687718,-0.24029329531427543,-0.3710941852773667,-0.1620462766525934,1.8951830310030808,1.5463078978712268,1.2955661860369987,0.7644910395751178,1.4712243043141844,-0.6078122100368903,-0.5550622157783601,1.2955661860369987,-0.1360020577956454,0.32968786719872717,5.413525936075921,-0.29255459388450233,-0.24029329531427543,2.167622859137434,0.6625960679420675,0.22669361755482975,0.04578676244131425,-0.4235539786397383,0.22669361755482975,0.4580535594777235,0.27822474270062764,0.14926757041348834,0.43241340517931676,-0.18810946914769616,-0.21419176492469524,0.40675685759510555,-0.2664141933665721,0.6880929270902055,-0.39731397995833206,-0.5023966694843781,-0.1620462766525934 | 3,246 |
Anion transport | 14 | 69 | 2.297196 | 0.021608 | P51798,P07602,Q7L0J3,Q9UHG3,Q9H2D1,Q9Y619,P54105,Q9UBX3,P41440,P30825,P21796,Q8TB61,P08183,P45880 | Processes and pathways | GO Biological process | msigdb_gobp | 251,65,96,103,71,303,174,143,108,215,53,218,250,31 | 1314,2892,2391,296,706,743,869,788,1380,2397,1575,2527,1269,65,250,2049,2769,2770,1391,908,511,53,1747,215,108,31,992,251,2209,951,174,1084,1991,1404,537,761,3086,1137,2148,3026,3219,2741,2944,96,1251,218,1479,2502,3171,967,390,1018,71,1426,2323,2918,1640,2104,2377,1727,598,143,103,1312,1111,1435,464,303,2560 | -0.05798197126028844,-0.7400651437154296,-0.4498143273913549,0.9928729317279787,0.3039647528659509,0.27822474270062764,0.2009022908471458,0.25246773267811196,-0.08397003066656783,-0.4498143273913549,-0.1620462766525934,-0.5023966694843781,-0.03201238316427893,3.049800312599363,1.1696891723387541,-0.31871463345796447,-0.6342192735405214,-0.6342192735405214,-0.08397003066656783,0.1750936448097422,0.5092850756510509,3.219774416782617,-0.21419176492469524,1.3458212477032034,2.2416791937316303,3.7990028619728236,0.1234239573228073,1.1696891723387541,-0.3710941852773667,0.14926757041348834,1.6212749135794295,0.07168366704405241,-0.29255459388450233,-0.08397003066656783,0.4836774176196852,0.27822474270062764,-0.9528376270712595,0.04578676244131425,-0.3448944504989137,-0.8462674242732842,-1.8755094393685137,-0.6078122100368903,-0.7665818624827188,2.389485348920194,-0.006061144709344608,1.3207004867153997,-0.10997668458835863,-0.47609517429475745,-1.274882183219594,0.14926757041348834,0.7135743175341883,0.1234239573228073,2.854945010826298,-0.08397003066656783,-0.39731397995833206,-0.7400651437154296,-0.1620462766525934,-0.31871463345796447,-0.4235539786397383,-0.18810946914769616,0.43241340517931676,1.8951830310030808,2.290992997439851,-0.03201238316427893,0.07168366704405241,-0.08397003066656783,0.5860117936562828,0.9928729317279787,-0.5023966694843781 | 3,246 |
Impaired social interactions | 8 | 46 | 2.291118 | 0.021957 | Q9UHX1,Q5KU26,Q96CU9,O96000,Q15067,Q9Y6M9,Q86Y39,O43676 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 0,69,73,203,263,145,282,95 | 1073,95,2841,1666,2394,1380,203,2725,2770,2528,3134,1182,2782,1845,2209,994,756,716,1341,2360,263,1534,69,1863,282,2690,1298,1790,73,2590,2321,2695,1717,2370,2696,2371,1303,2508,459,2836,2513,1311,295,0,701,145 | 0.07168366704405241,2.4140805364413698,-0.6870983502389405,-0.18810946914769616,-0.4498143273913549,-0.08397003066656783,1.4211029662479921,-0.6078122100368903,-0.6342192735405214,-0.5023966694843781,-1.086586487466602,0.019871864265687718,-0.6342192735405214,-0.24029329531427543,-0.3710941852773667,0.1234239573228073,0.27822474270062764,0.3039647528659509,-0.05798197126028844,-0.4235539786397383,1.119241145820181,-0.1360020577956454,2.854945010826298,-0.24029329531427543,1.0687366974464951,-0.5814265778010619,-0.03201238316427893,-0.21419176492469524,2.806129116763043,-0.5287189651896583,-0.39731397995833206,-0.5814265778010619,-0.18810946914769616,-0.4235539786397383,-0.5814265778010619,-0.4235539786397383,-0.03201238316427893,-0.47609517429475745,0.5860117936562828,-0.6606479316905032,-0.47609517429475745,-0.03201238316427893,1.0181752334237035,8.366255129812147,0.32968786719872717,1.8703440739483437 | 3,246 |
serine protease | 6 | 16 | 2.288103 | 0.022132 | Q8N2K0,P42785,P10619,Q16740,Q9H3G5,Q9HB40 | Functions | Panther Protein class | panther_protein_class | 355,7,199,38,313,57 | 2522,1073,199,2464,1582,1510,2967,7,2932,1282,38,371,355,313,57,2709 | -0.5023966694843781,0.07168366704405241,1.4461702390450293,-0.47609517429475745,-0.1620462766525934,-0.1360020577956454,-0.7931210294366591,5.248982947695327,-0.7665818624827188,-0.03201238316427893,3.461771979995661,0.739040326321,0.7899265425128388,0.9422248046510306,3.195521831934781,-0.5814265778010619 | 3,246 |
Parkinsons disease | 10 | 53 | 2.281812 | 0.0225 | P00846,O14949,P14406,O96000,Q9Y6M9,P21796,P00403,P22695,O43676,P45880 | Processes and pathways | KEGG Pathways | msigdb_kegg | 101,138,43,203,145,53,181,25,95,31 | 2606,1113,138,1073,422,95,3143,1266,2841,1666,2394,2811,3039,2766,2997,203,181,101,2527,830,2564,2343,832,1391,908,484,43,2961,2528,749,53,1228,2274,25,1229,1394,3134,2410,2133,1448,425,31,3061,2782,1984,1759,1462,2787,1621,2696,247,1111,145 | -0.5550622157783601,0.04578676244131425,1.9200098581999967,0.07168366704405241,0.6370836521056745,2.4140805364413698,-1.1134097681064297,-0.03201238316427893,-0.6870983502389405,-0.18810946914769616,-0.4498143273913549,-0.6606479316905032,-0.8728750171589886,-0.6342192735405214,-0.819682822993657,1.4211029662479921,1.5713097730015686,2.290992997439851,-0.5023966694843781,0.22669361755482975,-0.5287189651896583,-0.4235539786397383,0.22669361755482975,-0.08397003066656783,0.1750936448097422,0.5348766285518468,3.3650872278199344,-0.7931210294366591,-0.5023966694843781,0.27822474270062764,3.219774416782617,-0.006061144709344608,-0.39731397995833206,3.919014730047917,-0.006061144709344608,-0.08397003066656783,-1.086586487466602,-0.4498143273913549,-0.3448944504989137,-0.10997668458835863,0.6370836521056745,3.7990028619728236,-0.899505788360606,-0.6342192735405214,-0.29255459388450233,-0.21419176492469524,-0.10997668458835863,-0.6342192735405214,-0.1620462766525934,-0.5814265778010619,1.1948922097827732,0.07168366704405241,1.8703440739483437 | 3,246 |
Hand polydactyly | 7 | 31 | 2.280576 | 0.022574 | Q9UHX1,Q10713,Q15067,Q9BXW9,O96028,Q14739,O43924 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 0,170,263,240,213,126,64 | 2990,64,1501,213,2775,1032,1447,2210,2576,1128,800,170,880,2679,126,2424,263,3099,3199,283,811,2543,2174,240,2023,672,0,1651,2383,1652,1953 | -0.819682822993657,3.074111943417051,-0.1360020577956454,1.3458212477032034,-0.6342192735405214,0.09756269387250471,-0.10997668458835863,-0.3710941852773667,-0.5287189651896583,0.04578676244131425,0.25246773267811196,1.646238301853119,0.2009022908471458,-0.5814265778010619,2.0687191415996717,-0.4498143273913549,1.119241145820181,-0.9795390827213797,-1.5461400051345588,1.0687366974464951,0.25246773267811196,-0.5023966694843781,-0.3448944504989137,1.2200813591990216,-0.29255459388450233,0.355394188525345,8.366255129812147,-0.1620462766525934,-0.4235539786397383,-0.1620462766525934,-0.2664141933665721 | 3,246 |
Coated vesicle membrane | 16 | 62 | 2.27999 | 0.022608 | P24390,P10321,Q14108,P01130,O95487,O00291,P35606,Q9Y6B6,P11717,Q15437,Q9Y3B3,Q9Y6I3,Q9UBV8,P20645,P49257,Q8N511 | Localization | GO Cellular component | msigdb_gocc | 2,434,4,351,350,288,300,548,397,177,576,481,380,121,278,188 | 1659,288,703,1162,1665,1440,871,3133,1379,1825,2525,1964,350,2047,351,790,1076,711,1504,2342,434,1579,397,1508,121,2,300,1331,278,796,1036,2286,2062,1605,2210,2071,1910,1612,1522,1043,4,881,665,638,763,177,2906,188,2009,2590,1209,596,1485,1068,380,2862,1489,576,1372,548,481,824 | -0.18810946914769616,1.0181752334237035,0.3039647528659509,0.019871864265687718,-0.18810946914769616,-0.10997668458835863,0.2009022908471458,-1.086586487466602,-0.08397003066656783,-0.24029329531427543,-0.5023966694843781,-0.29255459388450233,0.7899265425128388,-0.31871463345796447,0.7899265425128388,0.25246773267811196,0.07168366704405241,0.3039647528659509,-0.1360020577956454,-0.4235539786397383,0.6115555906448871,-0.1620462766525934,0.6880929270902055,-0.1360020577956454,2.118194303237033,7.063640679323355,0.9928729317279787,-0.05798197126028844,1.0687366974464951,0.25246773267811196,0.09756269387250471,-0.39731397995833206,-0.31871463345796447,-0.1620462766525934,-0.3710941852773667,-0.31871463345796447,-0.2664141933665721,-0.1620462766525934,-0.1360020577956454,0.09756269387250471,5.4604731281181715,0.2009022908471458,0.355394188525345,0.38108381849412826,0.27822474270062764,1.5962987576738683,-0.7400651437154296,1.5212930700276128,-0.29255459388450233,-0.5287189651896583,0.019871864265687718,0.43241340517931676,-0.10997668458835863,0.09756269387250471,0.739040326321,-0.6870983502389405,-0.10997668458835863,0.4580535594777235,-0.05798197126028844,0.4836774176196852,0.5604521702536023,0.25246773267811196 | 3,246 |
Mitochondrion organization | 44 | 193 | 2.277656 | 0.022747 | P55786,Q15388,Q5HYI7,Q96A26,O60830,P50542,Q9Y6M9,Q9UDX5,Q9NS69,Q13505,Q86Y39,P49257,P0DP25,Q9H3K2,Q9Y512,P45880,Q9P0J0,Q15070,Q69YU5,P14406,Q10713,Q13501,O43674,Q8N2A8,Q99595,Q8N8Q8,P21796,Q99536,Q9Y5P4,Q96CU9,Q8N4H5,P04062,O96000,O14925,Q7L592,O14737,Q6DKK2,O43676,Q9Y3D6,O43819,P31749,O75153,Q9NUQ9,O75431 | Processes and pathways | GO Biological process | msigdb_gobp | 3,259,135,402,11,270,145,150,21,23,282,278,277,418,157,31,295,410,42,43,170,427,422,47,50,179,53,183,464,73,75,76,203,334,451,212,89,95,358,360,363,112,246,248 | 650,465,1659,935,1113,212,334,623,1073,938,422,95,3143,360,1266,1267,11,1378,871,112,2765,2841,1666,2119,248,2043,2394,654,2263,1500,2894,2265,3039,1501,2997,2664,1502,905,528,203,509,1385,1076,76,2192,1669,2527,945,1968,2565,277,1969,2197,1391,43,1829,53,1588,3057,3134,2929,2966,874,363,1327,1976,3059,2967,2874,3060,657,2134,31,1081,2731,278,1398,1517,2284,270,950,797,1083,1984,582,3,1907,1759,2290,3112,1763,170,427,23,2295,410,1618,259,883,682,2787,1621,803,2086,1345,2487,135,560,1469,2685,1863,42,89,2306,1704,451,3156,1865,282,453,1707,2429,2310,1472,2690,47,75,1350,179,1351,1790,2749,1628,2857,402,73,1713,2166,616,1012,1055,2696,183,50,2017,2888,644,1059,1013,1101,569,2371,890,2981,857,2594,1212,418,1065,2375,2246,1154,2105,21,1877,246,3108,1107,1644,2513,3193,523,1311,295,1488,150,738,3077,901,1652,2520,2764,1732,577,358,2865,1069,1070,157,699,464,549,145 | 0.355394188525345,0.5604521702536023,-0.18810946914769616,0.14926757041348834,0.04578676244131425,1.3458212477032034,0.8407522538471938,0.38108381849412826,0.07168366704405241,0.14926757041348834,0.6370836521056745,2.4140805364413698,-1.1134097681064297,0.7644910395751178,-0.03201238316427893,-0.03201238316427893,4.895169327756598,-0.08397003066656783,0.2009022908471458,2.2170052153908957,-0.6342192735405214,-0.6870983502389405,-0.18810946914769616,-0.3448944504989137,1.1696891723387541,-0.31871463345796447,-0.4498143273913549,0.355394188525345,-0.39731397995833206,-0.1360020577956454,-0.7400651437154296,-0.39731397995833206,-0.8728750171589886,-0.1360020577956454,-0.819682822993657,-0.5814265778010619,-0.1360020577956454,0.1750936448097422,0.4836774176196852,1.4211029662479921,0.5092850756510509,-0.08397003066656783,0.07168366704405241,2.732827412432188,-0.3710941852773667,-0.18810946914769616,-0.5023966694843781,0.14926757041348834,-0.29255459388450233,-0.5287189651896583,1.0687366974464951,-0.29255459388450233,-0.3710941852773667,-0.08397003066656783,3.3650872278199344,-0.24029329531427543,3.219774416782617,-0.1620462766525934,-0.899505788360606,-1.086586487466602,-0.7665818624827188,-0.7931210294366591,0.2009022908471458,0.7644910395751178,-0.05798197126028844,-0.29255459388450233,-0.899505788360606,-0.7931210294366591,-0.713570697362591,-0.899505788360606,0.355394188525345,-0.3448944504989137,3.7990028619728236,0.07168366704405241,-0.6078122100368903,1.0687366974464951,-0.08397003066656783,-0.1360020577956454,-0.39731397995833206,1.0939960112015843,0.14926757041348834,0.25246773267811196,0.07168366704405241,-0.29255459388450233,0.43241340517931676,5.788310865118061,-0.2664141933665721,-0.21419176492469524,-0.39731397995833206,-1.0330140600804507,-0.21419176492469524,1.646238301853119,0.6370836521056745,4.062740258133748,-0.39731397995833206,0.6625960679420675,-0.1620462766525934,1.14447217515618,0.2009022908471458,0.32968786719872717,-0.6342192735405214,-0.1620462766525934,0.25246773267811196,-0.31871463345796447,-0.05798197126028844,-0.47609517429475745,1.9448246105356892,0.4580535594777235,-0.10997668458835863,-0.5814265778010619,-0.24029329531427543,3.389272578075928,2.5859395556139195,-0.39731397995833206,-0.18810946914769616,0.5860117936562828,-1.167131539845109,-0.24029329531427543,1.0687366974464951,0.5860117936562828,-0.18810946914769616,-0.4498143273913549,-0.39731397995833206,-0.10997668458835863,-0.5814265778010619,3.3166879953213755,2.757271750668178,-0.05798197126028844,1.5962987576738683,-0.05798197126028844,-0.21419176492469524,-0.6078122100368903,-0.1620462766525934,-0.6870983502389405,0.6880929270902055,2.806129116763043,-0.18810946914769616,-0.3448944504989137,0.40675685759510555,0.1234239573228073,0.09756269387250471,-0.5814265778010619,1.5713097730015686,3.2682504863299298,-0.29255459388450233,-0.713570697362591,0.38108381849412826,0.09756269387250471,0.1234239573228073,0.07168366704405241,0.4580535594777235,-0.4235539786397383,0.2009022908471458,-0.7931210294366591,0.22669361755482975,-0.5287189651896583,0.019871864265687718,0.6625960679420675,0.09756269387250471,-0.4235539786397383,-0.3710941852773667,0.04578676244131425,-0.31871463345796447,4.2300299284583565,-0.24029329531427543,1.1948922097827732,-1.0062644931084461,0.07168366704405241,-0.1620462766525934,-0.47609517429475745,-1.4373042480210472,0.5092850756510509,-0.03201238316427893,1.0181752334237035,-0.10997668458835863,1.845492931563142,0.3039647528659509,-0.9261599274787706,0.2009022908471458,-0.1620462766525934,-0.47609517429475745,-0.6078122100368903,-0.18810946914769616,0.4580535594777235,0.7899265425128388,-0.6870983502389405,0.09756269387250471,0.09756269387250471,1.7459653822593797,0.32968786719872717,0.5860117936562828,0.4836774176196852,1.8703440739483437 | 3,246 |
Protein targeting to membrane | 11 | 35 | 2.276863 | 0.022794 | P31751,P40855,Q9Y5Y5,Q15629,Q9UL54,P46379,P50542,P27105,P43307,O60725,Q9Y3D6 | Processes and pathways | GO Biological process | msigdb_gobp | 195,227,261,166,369,10,270,238,156,30,358 | 2331,551,706,466,30,2523,2403,1446,238,1678,195,1683,227,156,10,1126,270,2934,1909,1520,3112,3176,166,2539,1794,2803,893,1877,648,368,2517,369,358,1435,261 | -0.4235539786397383,0.4580535594777235,0.3039647528659509,0.5604521702536023,3.7990028619728236,-0.5023966694843781,-0.4498143273913549,-0.10997668458835863,1.2200813591990216,-0.18810946914769616,1.4712243043141844,-0.18810946914769616,1.2704182773309,1.7459653822593797,4.989685390213567,0.04578676244131425,1.0939960112015843,-0.7665818624827188,-0.2664141933665721,-0.1360020577956454,-1.0330140600804507,-1.3018851715713253,1.6711889830807138,-0.5023966694843781,-0.21419176492469524,-0.6342192735405214,0.2009022908471458,-0.24029329531427543,0.38108381849412826,0.7644910395751178,-0.47609517429475745,0.7644910395751178,0.7899265425128388,-0.08397003066656783,1.14447217515618 | 3,246 |
EF-hand domain [IPR002048] | 13 | 45 | 2.267824 | 0.02334 | O75071,P41208,Q9BRK5,Q96AY3,Q14257,P80303,Q9UBV8,Q9NWM8,O43852,P0DP25,P35609,Q02818,Q8IYU8 | Sequence | InterPro Domain | interpro_domain | 258,34,260,99,106,16,380,118,189,277,469,27,413 | 1165,652,189,258,3133,1380,1501,1388,277,1122,2771,2345,3056,947,1591,1593,469,34,1080,2414,1188,16,27,3233,1092,106,2973,1770,2741,1707,2429,413,491,99,1938,1719,260,1064,2758,118,3131,782,380,1312,1217 | 0.019871864265687718,0.355394188525345,1.4962652266439553,1.14447217515618,-1.086586487466602,-0.08397003066656783,-0.1360020577956454,-0.08397003066656783,1.0687366974464951,0.04578676244131425,-0.6342192735405214,-0.4235539786397383,-0.899505788360606,0.14926757041348834,-0.1620462766525934,-0.1620462766525934,0.5604521702536023,3.7268890651643467,0.07168366704405241,-0.4498143273913549,0.019871864265687718,4.468304578365973,3.8470341251685394,-2.2655750573285,0.07168366704405241,2.266341771441869,-0.7931210294366591,-0.21419176492469524,-0.6078122100368903,-0.18810946914769616,-0.4498143273913549,0.6625960679420675,0.5348766285518468,2.3156329202480475,-0.2664141933665721,-0.18810946914769616,1.14447217515618,0.09756269387250471,-0.6078122100368903,2.1429143813660745,-1.059787988728998,0.27822474270062764,0.739040326321,-0.03201238316427893,0.019871864265687718 | 3,246 |
Regulation of plk1 activity at g2 m transition | 17 | 37 | 2.260558 | 0.023787 | P43034,Q15154,P41208,P62258,Q96CS2,P63167,O95067,P04350,O94927,O14965,Q13561,O95684,Q9H6D7,Q99996,P30153,O75935,Q15691 | Processes and pathways | Reactome Pathways | msigdb_reactome | 128,411,34,534,690,714,601,510,297,623,471,19,151,814,435,125,764 | 623,937,1317,125,297,601,19,510,944,1270,945,2568,1176,435,34,128,1985,2212,878,799,2935,534,714,1457,1690,1342,471,1467,2785,1003,2082,411,764,1785,690,814,151 | 0.38108381849412826,0.14926757041348834,-0.05798197126028844,2.0687191415996717,0.9928729317279787,0.40675685759510555,4.3492703956282925,0.5092850756510509,0.14926757041348834,-0.03201238316427893,0.14926757041348834,-0.5287189651896583,0.019871864265687718,0.6115555906448871,3.7268890651643467,2.0439639548690964,-0.29255459388450233,-0.3710941852773667,0.2009022908471458,0.25246773267811196,-0.7665818624827188,0.4836774176196852,0.3039647528659509,-0.10997668458835863,-0.18810946914769616,-0.05798197126028844,0.5604521702536023,-0.10997668458835863,-0.6342192735405214,0.1234239573228073,-0.31871463345796447,0.6625960679420675,0.27822474270062764,-0.21419176492469524,0.32968786719872717,0.25246773267811196,1.7957538664939172 | 3,246 |
Cyclin a cdk2 associated events at s phase entry | 11 | 46 | 2.25654 | 0.024037 | P31751,P20618,P49721,P11802,Q9UL46,P28070,P31749,P60900,O00231,P28072,P28074 | Processes and pathways | Reactome Pathways | msigdb_reactome | 195,290,5,383,406,142,363,114,304,184,224 | 304,3054,1315,1959,742,654,2768,383,1325,909,290,1509,1230,1179,1832,2203,1589,142,184,224,363,195,2730,2619,1515,676,5,1983,1847,114,408,840,1130,2355,1457,758,957,2678,1467,1698,1791,617,1940,406,2557,1652 | 0.9675561480174244,-0.899505788360606,-0.05798197126028844,-0.29255459388450233,0.27822474270062764,0.355394188525345,-0.6342192735405214,0.7135743175341883,-0.05798197126028844,0.1750936448097422,1.0181752334237035,-0.1360020577956454,-0.006061144709344608,0.019871864265687718,-0.24029329531427543,-0.3710941852773667,-0.1620462766525934,1.8951830310030808,1.5463078978712268,1.2955661860369987,0.7644910395751178,1.4712243043141844,-0.6078122100368903,-0.5550622157783601,-0.1360020577956454,0.32968786719872717,5.413525936075921,-0.29255459388450233,-0.24029329531427543,2.167622859137434,0.6625960679420675,0.22669361755482975,0.04578676244131425,-0.4235539786397383,-0.10997668458835863,0.27822474270062764,0.14926757041348834,-0.5814265778010619,-0.10997668458835863,-0.18810946914769616,-0.21419176492469524,0.40675685759510555,-0.2664141933665721,0.6880929270902055,-0.5023966694843781,-0.1620462766525934 | 3,246 |
Abnormality of the gingiva | 10 | 46 | 2.254756 | 0.024149 | P16278,P10644,Q96JJ3,Q14108,P04062,Q15392,P21281,P49257,Q14739,Q9NPE3 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 33,222,321,4,76,46,337,278,126,226 | 1657,1659,702,2718,2868,2998,76,2122,1445,222,3154,33,1745,337,2055,1749,3083,278,1398,352,1909,2624,1614,1761,1132,1616,4,126,2786,681,46,2223,768,2538,1348,2586,1474,321,2701,226,2028,672,2654,1651,2386,786 | -0.18810946914769616,-0.18810946914769616,0.3039647528659509,-0.6078122100368903,-0.713570697362591,-0.819682822993657,2.732827412432188,-0.3448944504989137,-0.10997668458835863,1.2955661860369987,-1.167131539845109,3.7268890651643467,-0.21419176492469524,0.8407522538471938,-0.31871463345796447,-0.21419176492469524,-0.9528376270712595,1.0687366974464951,-0.08397003066656783,0.7899265425128388,-0.2664141933665721,-0.5550622157783601,-0.1620462766525934,-0.21419176492469524,0.04578676244131425,-0.1620462766525934,5.4604731281181715,2.0687191415996717,-0.6342192735405214,0.32968786719872717,3.3166879953213755,-0.3710941852773667,0.27822474270062764,-0.5023966694843781,-0.05798197126028844,-0.5287189651896583,-0.10997668458835863,0.8915181244165605,-0.5814265778010619,1.2955661860369987,-0.29255459388450233,0.355394188525345,-0.5550622157783601,-0.1620462766525934,-0.4235539786397383,0.27822474270062764 | 3,246 |
Sphingolipid metabolism | 6 | 13 | 2.250832 | 0.024396 | P16278,P04062,O95470,Q16739,Q13510,Q06136 | Processes and pathways | KEGG Pathways | msigdb_kegg | 33,76,326,78,272,345 | 741,2893,706,326,76,370,2127,33,345,272,78,571,2106 | 0.27822474270062764,-0.7400651437154296,0.3039647528659509,0.8661426282602883,2.732827412432188,0.739040326321,-0.3448944504989137,3.7268890651643467,0.8153469194562949,1.0939960112015843,2.732827412432188,0.4580535594777235,-0.31871463345796447 | 3,246 |
Retrograde transport endosome to golgi | 8 | 35 | 2.249285 | 0.024494 | O15260,O75503,Q4J6C6,Q8NBN3,P53367,P49257,P40616,Q9Y5X3 | Processes and pathways | GO Biological process | msigdb_gobp | 63,82,371,84,55,278,343,324 | 63,978,940,1820,395,942,1118,82,1177,343,278,1454,2416,55,1522,1043,1287,1003,371,2486,847,2689,1543,2946,84,851,1419,616,1017,1423,2515,673,3052,674,324 | 3.074111943417051,0.1234239573228073,0.14926757041348834,-0.24029329531427543,0.6880929270902055,0.14926757041348834,0.04578676244131425,2.634944712077862,0.019871864265687718,0.8153469194562949,1.0687366974464951,-0.10997668458835863,-0.4498143273913549,3.195521831934781,-0.1360020577956454,0.09756269387250471,-0.03201238316427893,0.1234239573228073,0.739040326321,-0.47609517429475745,0.22669361755482975,-0.5814265778010619,-0.1360020577956454,-0.7665818624827188,2.634944712077862,0.22669361755482975,-0.08397003066656783,0.40675685759510555,0.1234239573228073,-0.08397003066656783,-0.47609517429475745,0.355394188525345,-0.8728750171589886,0.355394188525345,0.8915181244165605 | 3,246 |
Protease binding | 10 | 25 | 2.248147 | 0.024567 | P07602,P01130,O75955,P04080,Q9GZP9,P46379,P42574,P14174,P41440,Q9BUN8 | Functions | GO Molecular function | msigdb_gomf | 65,351,504,289,268,10,425,511,108,417 | 2841,504,1169,351,289,1669,1269,2195,65,511,1394,1591,1977,108,425,10,2064,1522,719,1773,1717,2696,417,268,598 | -0.6870983502389405,0.5092850756510509,0.019871864265687718,0.7899265425128388,1.0181752334237035,-0.18810946914769616,-0.03201238316427893,-0.3710941852773667,3.049800312599363,0.5092850756510509,-0.08397003066656783,-0.1620462766525934,-0.29255459388450233,2.2416791937316303,0.6370836521056745,4.989685390213567,-0.31871463345796447,-0.1360020577956454,0.3039647528659509,-0.21419176492469524,-0.18810946914769616,-0.5814265778010619,0.6625960679420675,1.119241145820181,0.43241340517931676 | 3,246 |
Establishment of protein localization to membrane | 20 | 87 | 2.245238 | 0.024753 | O15118,Q9Y5Y5,P46379,P50542,Q9NS69,P0DP25,P43307,Q9Y512,O60725,Q9P0J0,Q15629,Q9HD20,Q8N8Q8,P31751,O14737,Q9Y3D6,P40855,Q9UL54,Q9UHB9,P27105 | Processes and pathways | GO Biological process | msigdb_gobp | 131,261,10,270,21,277,156,157,30,295,166,51,179,195,212,358,227,369,368,238 | 2331,1659,551,212,1162,131,2336,706,466,30,2610,2523,1500,2459,1320,945,2403,1446,277,238,874,1678,195,1327,1683,227,2572,156,10,1980,1126,270,1454,1606,2934,2212,1909,2068,1520,3023,3112,756,3176,470,2581,2221,1137,410,166,1532,371,2487,610,2539,1543,2586,179,1145,1628,642,616,1794,3006,2803,1065,1104,893,51,2104,2551,21,1877,3094,295,648,368,2517,785,3052,369,1217,2520,358,1435,157,699,261 | -0.4235539786397383,-0.18810946914769616,0.4580535594777235,1.3458212477032034,0.019871864265687718,1.994418108265382,-0.4235539786397383,0.3039647528659509,0.5604521702536023,3.7990028619728236,-0.5550622157783601,-0.5023966694843781,-0.1360020577956454,-0.47609517429475745,-0.05798197126028844,0.14926757041348834,-0.4498143273913549,-0.10997668458835863,1.0687366974464951,1.2200813591990216,0.2009022908471458,-0.18810946914769616,1.4712243043141844,-0.05798197126028844,-0.18810946914769616,1.2704182773309,-0.5287189651896583,1.7459653822593797,4.989685390213567,-0.29255459388450233,0.04578676244131425,1.0939960112015843,-0.10997668458835863,-0.1620462766525934,-0.7665818624827188,-0.3710941852773667,-0.2664141933665721,-0.31871463345796447,-0.1360020577956454,-0.8462674242732842,-1.0330140600804507,0.27822474270062764,-1.3018851715713253,0.5604521702536023,-0.5287189651896583,-0.3710941852773667,0.04578676244131425,0.6625960679420675,1.6711889830807138,-0.1360020577956454,0.739040326321,-0.47609517429475745,0.40675685759510555,-0.5023966694843781,-0.1360020577956454,-0.5287189651896583,1.5962987576738683,0.04578676244131425,-0.1620462766525934,0.38108381849412826,0.40675685759510555,-0.21419176492469524,-0.819682822993657,-0.6342192735405214,0.09756269387250471,0.07168366704405241,0.2009022908471458,3.2682504863299298,-0.31871463345796447,-0.5023966694843781,4.2300299284583565,-0.24029329531427543,-0.9528376270712595,1.0181752334237035,0.38108381849412826,0.7644910395751178,-0.47609517429475745,0.27822474270062764,-0.8728750171589886,0.7644910395751178,0.019871864265687718,-0.47609517429475745,0.7899265425128388,-0.08397003066656783,1.7459653822593797,0.32968786719872717,1.14447217515618 | 3,246 |
Cognitive impairment | 38 | 173 | 2.238147 | 0.025211 | O15118,Q14108,Q9Y5Y5,O76024,Q9BQE5,P50542,Q13510,Q9NQZ5,Q9H9S5,P16278,Q9NZ08,Q6PGP7,P04080,Q9Y619,Q10713,Q15437,P00403,Q92889,Q99720,P07602,P50897,P07196,P04062,O95470,O75503,P17900,Q6DKK2,P54802,P10644,P40855,P00846,P61916,O43819,P35637,P31749,P06280,Q7LG56,Q9Y487 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 131,4,261,382,12,270,272,149,419,33,35,428,289,303,170,177,181,316,62,65,66,327,76,326,82,214,89,217,222,227,101,105,360,364,363,370,373,122 | 935,3079,131,1073,706,360,1267,1737,745,1666,2338,82,708,382,2265,2399,326,528,509,3191,181,101,790,76,289,510,1669,1172,370,2193,327,65,3105,2401,554,2815,2124,3018,222,2770,1391,2127,33,2666,214,1326,3111,1745,2775,1228,1032,2274,1123,2277,1588,2410,363,1682,364,1328,1276,227,1035,2281,2134,1684,876,2415,1452,1599,837,1398,270,66,2137,1845,2138,1603,217,1846,2064,661,1608,2211,1520,105,799,1522,756,1614,1524,2142,1852,716,2477,170,3137,2292,717,2847,999,427,272,4,1003,1343,2360,2633,1927,177,2299,2003,1535,1863,89,2686,1140,428,586,2687,2830,373,3199,563,1350,2009,771,1300,2096,316,3048,2315,2796,616,1012,1717,3103,2696,2914,2888,62,12,2371,2173,1303,419,1106,459,1154,2023,149,2024,1726,2652,35,598,478,1952,694,2031,1312,2328,2182,903,3166,1953,2865,122,1070,1023,261,303,1656 | 0.14926757041348834,-0.9528376270712595,1.994418108265382,0.07168366704405241,0.3039647528659509,0.7644910395751178,-0.03201238316427893,-0.21419176492469524,0.27822474270062764,-0.18810946914769616,-0.4235539786397383,2.634944712077862,0.3039647528659509,0.7135743175341883,-0.39731397995833206,-0.4498143273913549,0.8661426282602883,0.4836774176196852,0.5092850756510509,-1.4373042480210472,1.5713097730015686,2.290992997439851,0.25246773267811196,2.732827412432188,1.0181752334237035,0.5092850756510509,-0.18810946914769616,0.019871864265687718,0.739040326321,-0.3710941852773667,0.8661426282602883,3.049800312599363,-1.0062644931084461,-0.4498143273913549,0.4580535594777235,-0.6606479316905032,-0.3448944504989137,-0.8462674242732842,1.2955661860369987,-0.6342192735405214,-0.08397003066656783,-0.3448944504989137,3.7268890651643467,-0.5814265778010619,1.3458212477032034,-0.05798197126028844,-1.0330140600804507,-0.21419176492469524,-0.6342192735405214,-0.006061144709344608,0.09756269387250471,-0.39731397995833206,0.04578676244131425,-0.39731397995833206,-0.1620462766525934,-0.4498143273913549,0.7644910395751178,-0.18810946914769616,0.7644910395751178,-0.05798197126028844,-0.03201238316427893,1.2704182773309,0.09756269387250471,-0.39731397995833206,-0.3448944504989137,-0.18810946914769616,0.2009022908471458,-0.4498143273913549,-0.10997668458835863,-0.1620462766525934,0.22669361755482975,-0.08397003066656783,1.0939960112015843,2.8793375078697796,-0.3448944504989137,-0.24029329531427543,-0.3448944504989137,-0.1620462766525934,1.3207004867153997,-0.24029329531427543,-0.31871463345796447,0.355394188525345,-0.1620462766525934,-0.3710941852773667,-0.1360020577956454,2.266341771441869,0.25246773267811196,-0.1360020577956454,0.27822474270062764,-0.1620462766525934,-0.1360020577956454,-0.3448944504989137,-0.24029329531427543,0.3039647528659509,-0.47609517429475745,1.646238301853119,-1.086586487466602,-0.39731397995833206,0.3039647528659509,-0.6870983502389405,0.1234239573228073,0.6370836521056745,1.0939960112015843,5.4604731281181715,0.1234239573228073,-0.05798197126028844,-0.4235539786397383,-0.5550622157783601,-0.2664141933665721,1.5962987576738683,-0.39731397995833206,-0.29255459388450233,-0.1360020577956454,-0.24029329531427543,2.5859395556139195,-0.5814265778010619,0.04578676244131425,0.6370836521056745,0.43241340517931676,-0.5814265778010619,-0.6606479316905032,0.739040326321,-1.5461400051345588,0.4580535594777235,-0.05798197126028844,-0.29255459388450233,0.27822474270062764,-0.03201238316427893,-0.31871463345796447,0.91687882319615,-0.8728750171589886,-0.39731397995833206,-0.6342192735405214,0.40675685759510555,0.1234239573228073,-0.18810946914769616,-0.9795390827213797,-0.5814265778010619,-0.7400651437154296,-0.713570697362591,3.0984136398458118,4.7768512995189685,-0.4235539786397383,-0.3448944504989137,-0.03201238316427893,0.6625960679420675,0.07168366704405241,0.5860117936562828,0.04578676244131425,-0.29255459388450233,1.845492931563142,-0.29255459388450233,-0.18810946914769616,-0.5550622157783601,3.7028331681230524,0.43241340517931676,0.5604521702536023,-0.2664141933665721,0.32968786719872717,-0.29255459388450233,-0.03201238316427893,-0.39731397995833206,-0.3448944504989137,0.2009022908471458,-1.2209550696577467,-0.2664141933665721,-0.6870983502389405,2.118194303237033,0.09756269387250471,0.1234239573228073,1.14447217515618,0.9928729317279787,-0.1620462766525934 | 3,246 |
Abnormality of corneal stroma | 7 | 14 | 2.237059 | 0.025282 | P16278,P10619,P04062,P50542,Q13510,Q92889,O43505 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 33,199,76,270,272,316,158 | 158,351,76,199,33,1326,3111,270,1846,3175,272,683,1140,316 | 1.7210524640385625,0.7899265425128388,2.732827412432188,1.4461702390450293,3.7268890651643467,-0.05798197126028844,-1.0330140600804507,1.0939960112015843,-0.24029329531427543,-1.3018851715713253,1.0939960112015843,0.32968786719872717,0.04578676244131425,0.91687882319615 | 3,246 |
External side of plasma membrane | 7 | 26 | 2.23505 | 0.025414 | P01130,O15439,P41440,P42892,P07858,Q08431,P08183 | Localization | GO Cellular component | msigdb_gocc | 351,296,108,54,153,314,250 | 296,504,906,602,629,351,1076,1575,1269,907,153,250,791,1323,362,3056,2204,108,54,1452,992,314,1005,1538,1349,1426 | 0.9928729317279787,0.5092850756510509,0.1750936448097422,0.40675685759510555,0.38108381849412826,0.7899265425128388,0.07168366704405241,-0.1620462766525934,-0.03201238316427893,0.1750936448097422,1.7708658304290625,1.1696891723387541,0.25246773267811196,-0.05798197126028844,0.7644910395751178,-0.899505788360606,-0.3710941852773667,2.2416791937316303,3.195521831934781,-0.10997668458835863,0.1234239573228073,0.91687882319615,0.1234239573228073,-0.1360020577956454,-0.05798197126028844,-0.08397003066656783 | 3,246 |
AH/BAR domain superfamily [IPR027267] | 7 | 13 | 2.234794 | 0.025431 | Q9UKS6,Q9UKG1,Q9Y5X1,Q9UQB8,Q9UNH7,P53367,Q9Y5X3 | Sequence | InterPro Superfamily | interpro_homologous_superfamily | 695,499,141,15,674,55,324 | 942,55,1287,685,1871,499,695,1809,674,15,1732,141,324 | 0.14926757041348834,3.195521831934781,-0.03201238316427893,0.32968786719872717,-0.24029329531427543,0.5348766285518468,0.32968786719872717,-0.21419176492469524,0.355394188525345,4.492086951134466,-0.18810946914769616,1.9200098581999967,0.8915181244165605 | 3,246 |
Organic acid transport | 13 | 49 | 2.234711 | 0.025436 | Q7L0J3,P31751,P23786,Q9H2D1,Q9Y619,O15439,O43772,Q9UBX3,P31749,P41440,P30825,P08183,Q9Y3D6 | Processes and pathways | GO Biological process | msigdb_gobp | 96,195,329,71,303,296,13,143,363,108,215,250,358 | 2391,296,13,743,788,1380,2397,2459,2896,1575,1269,2401,250,2049,2770,511,329,1747,3145,215,363,195,2411,108,533,2209,951,1084,3155,1404,1137,2148,2944,1046,96,1251,416,1479,967,71,1426,2323,2918,1640,2377,143,1312,358,303 | -0.4498143273913549,0.9928729317279787,4.70576711199326,0.27822474270062764,0.25246773267811196,-0.08397003066656783,-0.4498143273913549,-0.47609517429475745,-0.7400651437154296,-0.1620462766525934,-0.03201238316427893,-0.4498143273913549,1.1696891723387541,-0.31871463345796447,-0.6342192735405214,0.5092850756510509,0.8661426282602883,-0.21419176492469524,-1.1134097681064297,1.3458212477032034,0.7644910395751178,1.4712243043141844,-0.4498143273913549,2.2416791937316303,0.4836774176196852,-0.3710941852773667,0.14926757041348834,0.07168366704405241,-1.167131539845109,-0.08397003066656783,0.04578676244131425,-0.3448944504989137,-0.7665818624827188,0.09756269387250471,2.389485348920194,-0.006061144709344608,0.6625960679420675,-0.10997668458835863,0.14926757041348834,2.854945010826298,-0.08397003066656783,-0.39731397995833206,-0.7400651437154296,-0.1620462766525934,-0.4235539786397383,1.8951830310030808,-0.03201238316427893,0.7899265425128388,0.9928729317279787 | 3,246 |
Perinuclear region of cytoplasm | 28 | 191 | 2.222397 | 0.026256 | P43034,O15118,O95684,P07858,Q8NEW0,P16278,Q9Y605,Q8IXJ6,Q15437,P42892,O75312,Q66K74,P84085,Q9Y4G8,O75503,O94788,Q99523,Q93050,Q9NQX7,P46934,P09601,Q8TAG9,Q01105,Q07065,Q9UIQ6,P20645,Q9Y487,O75935 | Localization | GO Cellular component | msigdb_gocc | 128,131,19,153,28,33,167,172,177,54,187,196,72,81,82,83,209,85,211,225,98,231,234,235,119,121,122,125 | 975,1314,935,2391,623,977,1162,131,1072,652,2718,1665,1816,940,395,1377,1029,1440,871,3015,187,3133,82,708,1381,125,83,2525,505,2459,19,528,1169,1076,1888,1172,1269,2842,153,945,2402,2048,1225,984,1968,98,1271,1579,791,397,1970,946,33,2817,1176,3056,1585,1830,1507,121,2130,2819,792,1231,1180,238,3057,2204,2054,2532,1511,1234,949,1748,2573,2281,2134,54,128,2135,3083,225,2057,1398,658,437,1083,2064,1519,556,1129,2068,1335,2215,3023,72,234,1917,716,235,1088,1341,956,1132,1993,1529,1465,3024,2738,1135,1004,881,681,1618,763,177,884,2086,2151,847,196,2830,1201,720,887,2232,1625,172,2946,1350,2157,2365,28,231,2750,1791,1356,85,1476,2544,2694,616,2696,209,733,496,1870,734,2914,2591,2549,2594,2550,858,1064,1256,1723,442,1257,2758,2101,432,1306,1556,211,2025,323,1951,1646,478,524,2111,119,862,1489,933,1563,480,2181,620,1218,697,2924,122,81,2388,464,324,167,2560,701 | 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| 3,246 |
Abnormal bleeding | 21 | 105 | 2.216433 | 0.026662 | Q9UHX1,P51798,Q14108,O76024,P49257,Q9NZ08,Q13126,O75844,Q86YV9,Q96JJ3,P23786,Q96PU5,P04062,P11117,P10644,Q8NCH0,P31749,Q9BXW9,Q9NWM8,Q9Y487,Q14739 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 0,251,4,382,278,35,41,190,319,321,329,200,76,223,222,230,363,240,118,122,126 | 465,2990,1659,1027,1819,1439,1119,190,382,790,1385,76,1669,1172,3213,1577,2665,2768,2122,2960,222,223,1122,1322,2345,1972,1176,2775,1228,1032,2129,329,2132,2204,2843,2410,2206,363,3226,1748,512,1328,2412,398,1276,1749,3069,876,3083,278,1452,1752,1398,658,251,1603,2062,2210,1128,2211,2213,2877,1761,1041,1762,1404,1918,1191,3137,41,4,3073,126,2786,1618,683,2299,3026,2538,1348,1290,319,1350,2158,230,811,2543,3048,2315,321,200,240,1256,2375,118,35,1560,648,0,1312,501,2386,122,701,1656 | 0.5604521702536023,-0.819682822993657,-0.18810946914769616,0.09756269387250471,-0.24029329531427543,-0.10997668458835863,0.04578676244131425,1.4962652266439553,0.7135743175341883,0.25246773267811196,-0.08397003066656783,2.732827412432188,-0.18810946914769616,0.019871864265687718,-1.8203017353449789,-0.1620462766525934,-0.5814265778010619,-0.6342192735405214,-0.3448944504989137,-0.7931210294366591,1.2955661860369987,1.2955661860369987,0.04578676244131425,-0.05798197126028844,-0.4235539786397383,-0.29255459388450233,0.019871864265687718,-0.6342192735405214,-0.006061144709344608,0.09756269387250471,-0.3448944504989137,0.8661426282602883,-0.3448944504989137,-0.3710941852773667,-0.6870983502389405,-0.4498143273913549,-0.3710941852773667,0.7644910395751178,-2.0419198439191044,-0.21419176492469524,0.5092850756510509,-0.05798197126028844,-0.4498143273913549,0.6880929270902055,-0.03201238316427893,-0.21419176492469524,-0.9261599274787706,0.2009022908471458,-0.9528376270712595,1.0687366974464951,-0.10997668458835863,-0.21419176492469524,-0.08397003066656783,0.355394188525345,1.1696891723387541,-0.1620462766525934,-0.31871463345796447,-0.3710941852773667,0.04578676244131425,-0.3710941852773667,-0.3710941852773667,-0.713570697362591,-0.21419176492469524,0.09756269387250471,-0.21419176492469524,-0.08397003066656783,-0.2664141933665721,0.019871864265687718,-1.086586487466602,3.389272578075928,5.4604731281181715,-0.9261599274787706,2.0687191415996717,-0.6342192735405214,-0.1620462766525934,0.32968786719872717,-0.39731397995833206,-0.8462674242732842,-0.5023966694843781,-0.05798197126028844,-0.03201238316427893,0.8915181244165605,-0.05798197126028844,-0.3448944504989137,1.2704182773309,0.25246773267811196,-0.5023966694843781,-0.8728750171589886,-0.39731397995833206,0.8915181244165605,1.4461702390450293,1.2200813591990216,-0.006061144709344608,-0.4235539786397383,2.1429143813660745,3.7028331681230524,-0.1360020577956454,0.38108381849412826,8.366255129812147,-0.03201238316427893,0.5348766285518468,-0.4235539786397383,2.118194303237033,0.32968786719872717,-0.1620462766525934 | 3,246 |
Toll like receptor signaling pathway | 6 | 15 | 2.214945 | 0.026764 | Q5KU26,Q9NQC3,Q9UKG1,P41440,Q9NPR9,P51812 | Processes and pathways | GO Biological process | msigdb_gobp | 69,333,499,108,420,279 | 1659,1567,504,1169,2402,1174,1969,108,279,1921,1004,69,420,333,499 | -0.18810946914769616,-0.1620462766525934,0.5092850756510509,0.019871864265687718,-0.4498143273913549,0.019871864265687718,-0.29255459388450233,2.2416791937316303,1.0687366974464951,-0.2664141933665721,0.1234239573228073,2.854945010826298,0.6625960679420675,0.8661426282602883,0.5348766285518468 | 3,246 |
Sphingolipid metabolism | 6 | 10 | 2.210465 | 0.027073 | P07602,P04062,O95470,Q16739,Q13510,P17900 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 65,76,326,78,272,214 | 741,2893,326,76,65,214,345,272,78,3050 | 0.27822474270062764,-0.7400651437154296,0.8661426282602883,2.732827412432188,3.049800312599363,1.3458212477032034,0.8153469194562949,1.0939960112015843,2.732827412432188,-0.8728750171589886 | 3,246 |
Negative regulation of notch4 signaling | 9 | 41 | 2.208495 | 0.02721 | P20618,P49721,Q9UL46,P28070,P31749,P60900,O00231,P28072,P28074 | Processes and pathways | Reactome Pathways | msigdb_reactome | 290,5,406,142,363,114,304,184,224 | 304,3054,1315,1959,742,654,1325,290,1230,1179,1832,2203,1589,142,184,224,363,2730,2619,1515,676,5,1983,1847,114,408,840,1130,2355,955,1457,758,957,1467,1698,1791,617,1940,406,2557,1374 | 0.9675561480174244,-0.899505788360606,-0.05798197126028844,-0.29255459388450233,0.27822474270062764,0.355394188525345,-0.05798197126028844,1.0181752334237035,-0.006061144709344608,0.019871864265687718,-0.24029329531427543,-0.3710941852773667,-0.1620462766525934,1.8951830310030808,1.5463078978712268,1.2955661860369987,0.7644910395751178,-0.6078122100368903,-0.5550622157783601,-0.1360020577956454,0.32968786719872717,5.413525936075921,-0.29255459388450233,-0.24029329531427543,2.167622859137434,0.6625960679420675,0.22669361755482975,0.04578676244131425,-0.4235539786397383,0.14926757041348834,-0.10997668458835863,0.27822474270062764,0.14926757041348834,-0.10997668458835863,-0.18810946914769616,-0.21419176492469524,0.40675685759510555,-0.2664141933665721,0.6880929270902055,-0.5023966694843781,-0.05798197126028844 | 3,246 |
EF-Hand 1, calcium-binding site [IPR018247] | 8 | 38 | 2.201432 | 0.027705 | P41208,Q9BRK5,Q96AY3,Q14257,P80303,Q9NWM8,O43852,Q02818 | Sequence | InterPro Binding site | interpro_binding_site | 34,260,99,106,16,118,189,27 | 652,189,3133,1380,1501,1388,277,1122,2771,2345,3056,947,1591,1593,34,1080,2414,16,27,3233,1092,106,2973,1770,2741,1707,2429,99,1938,1719,260,1064,2758,118,3131,782,380,1217 | 0.355394188525345,1.4962652266439553,-1.086586487466602,-0.08397003066656783,-0.1360020577956454,-0.08397003066656783,1.0687366974464951,0.04578676244131425,-0.6342192735405214,-0.4235539786397383,-0.899505788360606,0.14926757041348834,-0.1620462766525934,-0.1620462766525934,3.7268890651643467,0.07168366704405241,-0.4498143273913549,4.468304578365973,3.8470341251685394,-2.2655750573285,0.07168366704405241,2.266341771441869,-0.7931210294366591,-0.21419176492469524,-0.6078122100368903,-0.18810946914769616,-0.4498143273913549,2.3156329202480475,-0.2664141933665721,-0.18810946914769616,1.14447217515618,0.09756269387250471,-0.6078122100368903,2.1429143813660745,-1.059787988728998,0.27822474270062764,0.739040326321,0.019871864265687718 | 3,246 |
Azurophil granule membrane | 11 | 25 | 2.199042 | 0.027875 | O15260,P07602,Q9NZJ7,O00462,P42785,Q07065,Q8NF37,P10253,P15291,P27105,Q9NQX7 | Localization | GO Cellular component | msigdb_gocc | 63,65,598,503,7,235,491,298,362,238,211 | 503,63,2042,2956,745,1826,873,65,298,791,362,238,2207,7,1844,1036,235,2088,491,614,1634,3033,211,598,1646 | 0.5092850756510509,3.074111943417051,-0.31871463345796447,-0.7931210294366591,0.27822474270062764,-0.24029329531427543,0.2009022908471458,3.049800312599363,0.9928729317279787,0.25246773267811196,0.7644910395751178,1.2200813591990216,-0.3710941852773667,5.248982947695327,-0.24029329531427543,0.09756269387250471,1.2452566916042276,-0.31871463345796447,0.5348766285518468,0.40675685759510555,-0.1620462766525934,-0.8462674242732842,1.3709285366908623,0.43241340517931676,-0.1620462766525934 | 3,246 |
Nephropathy | 8 | 21 | 2.197151 | 0.02801 | P43034,Q14108,O76024,P35579,Q9UKG1,Q10713,P00403,P06280 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 128,4,382,512,499,170,181,370 | 2332,382,181,1966,370,512,2930,128,661,1608,1520,534,170,4,1140,1350,1300,1256,2596,1106,499 | -0.4235539786397383,0.7135743175341883,1.5713097730015686,-0.29255459388450233,0.739040326321,0.5092850756510509,-0.7665818624827188,2.0439639548690964,0.355394188525345,-0.1620462766525934,-0.1360020577956454,0.4836774176196852,1.646238301853119,5.4604731281181715,0.04578676244131425,-0.05798197126028844,-0.03201238316427893,-0.006061144709344608,-0.5287189651896583,0.07168366704405241,0.5348766285518468 | 3,246 |
Lysosomal transport | 13 | 46 | 2.196354 | 0.028067 | P07602,Q07954,O15118,Q14108,Q9Y2T2,Q9NZJ7,P20645,Q99816,Q96L92,P11717,Q99523,O14617,P46934 | Processes and pathways | GO Biological process | msigdb_gobp | 65,409,131,4,463,598,121,593,208,397,209,553,225 | 1659,553,787,977,131,1115,1665,872,65,1579,791,397,121,225,1454,1036,2064,409,4,847,2635,2540,1543,2946,1299,2312,2544,208,616,209,593,1256,1483,2803,2596,1154,971,1158,598,2381,2030,2515,933,1563,903,463 | -0.18810946914769616,0.4580535594777235,0.25246773267811196,0.1234239573228073,1.994418108265382,0.04578676244131425,-0.18810946914769616,0.2009022908471458,3.049800312599363,-0.1620462766525934,0.25246773267811196,0.6880929270902055,2.118194303237033,1.2955661860369987,-0.10997668458835863,0.09756269387250471,-0.31871463345796447,0.6625960679420675,5.4604731281181715,0.22669361755482975,-0.5550622157783601,-0.5023966694843781,-0.1360020577956454,-0.7665818624827188,-0.03201238316427893,-0.39731397995833206,-0.5023966694843781,1.3960224207311585,0.40675685759510555,1.3960224207311585,0.43241340517931676,-0.006061144709344608,-0.10997668458835863,-0.6342192735405214,-0.5287189651896583,0.04578676244131425,0.14926757041348834,0.04578676244131425,0.43241340517931676,-0.4235539786397383,-0.29255459388450233,-0.47609517429475745,0.1750936448097422,-0.1360020577956454,0.2009022908471458,0.5860117936562828 | 3,246 |
Antigen processing ubiquitination proteasome degradation | 17 | 91 | 2.196079 | 0.028086 | P55786,P20618,P49721,Q9BSL1,P61289,Q9UJX2,Q96PU5,P19474,P28070,Q9UL46,P60900,O00231,Q9UIQ6,P28072,Q9UBS8,P28074,P46934 | Processes and pathways | Reactome Pathways | msigdb_reactome | 3,290,5,267,408,462,200,77,142,406,114,304,119,184,155,224,225 | 2037,304,3054,1315,1959,742,654,628,1823,2664,1325,77,290,2274,1230,1179,1832,2203,1589,142,184,224,1510,1233,2730,2619,225,1515,676,5,1983,1037,1847,3,114,1755,1238,635,408,840,1130,2355,1457,1759,1131,758,957,2678,1467,2144,1194,1093,2294,449,585,1698,845,1619,3001,1620,1245,2151,2152,1347,2908,1865,2093,1791,1207,1868,2500,200,617,1940,267,1423,1303,1482,155,119,462,784,1214,2032,406,2114,2328,2557,2865,649,1810 | -0.31871463345796447,0.9675561480174244,-0.899505788360606,-0.05798197126028844,-0.29255459388450233,0.27822474270062764,0.355394188525345,0.38108381849412826,-0.24029329531427543,-0.5814265778010619,-0.05798197126028844,2.732827412432188,1.0181752334237035,-0.39731397995833206,-0.006061144709344608,0.019871864265687718,-0.24029329531427543,-0.3710941852773667,-0.1620462766525934,1.8951830310030808,1.5463078978712268,1.2955661860369987,-0.1360020577956454,-0.006061144709344608,-0.6078122100368903,-0.5550622157783601,1.2955661860369987,-0.1360020577956454,0.32968786719872717,5.413525936075921,-0.29255459388450233,0.09756269387250471,-0.24029329531427543,5.788310865118061,2.167622859137434,-0.21419176492469524,-0.006061144709344608,0.38108381849412826,0.6625960679420675,0.22669361755482975,0.04578676244131425,-0.4235539786397383,-0.10997668458835863,-0.21419176492469524,0.04578676244131425,0.27822474270062764,0.14926757041348834,-0.5814265778010619,-0.10997668458835863,-0.3448944504989137,0.019871864265687718,0.07168366704405241,-0.39731397995833206,0.5860117936562828,0.43241340517931676,-0.18810946914769616,0.22669361755482975,-0.1620462766525934,-0.819682822993657,-0.1620462766525934,-0.006061144709344608,-0.3448944504989137,-0.3448944504989137,-0.05798197126028844,-0.7400651437154296,-0.24029329531427543,-0.31871463345796447,-0.21419176492469524,0.019871864265687718,-0.24029329531427543,-0.47609517429475745,1.4461702390450293,0.40675685759510555,-0.2664141933665721,1.119241145820181,-0.08397003066656783,-0.03201238316427893,-0.10997668458835863,1.7708658304290625,2.1429143813660745,0.5860117936562828,0.27822474270062764,0.019871864265687718,-0.29255459388450233,0.6880929270902055,-0.31871463345796447,-0.39731397995833206,-0.5023966694843781,-0.6870983502389405,0.38108381849412826,-0.21419176492469524 | 3,246 |
Abnormalities of placenta or umbilical cord | 6 | 14 | 2.186746 | 0.028761 | P16278,Q6PGP7,P21281,Q9H4L7,O75844,O96017 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 33,428,337,474,190,529 | 625,190,1169,529,1385,1669,33,1272,337,1033,756,1860,428,474 | 0.38108381849412826,1.4962652266439553,0.019871864265687718,0.4836774176196852,-0.08397003066656783,-0.18810946914769616,3.7268890651643467,-0.03201238316427893,0.8407522538471938,0.09756269387250471,0.27822474270062764,-0.24029329531427543,0.6370836521056745,0.5604521702536023 | 3,246 |
Electron transport | 12 | 44 | 2.185649 | 0.028841 | Q9H1E5,Q96CU9,O14949,O96000,Q9Y6M9,P00403,Q86Y39,O43169,Q6DKK2,P22695,Q9UDW1,O43676 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 269,73,138,203,145,181,282,120,89,25,247,95 | 2606,138,120,825,422,95,3143,1266,2841,1666,2394,3039,2766,2997,982,203,181,2564,2344,2961,2528,1228,2569,25,3134,2410,2133,2968,2782,1984,440,2787,1621,1623,89,282,73,2499,269,521,2513,295,247,145 | -0.5550622157783601,1.9200098581999967,2.118194303237033,0.22669361755482975,0.6370836521056745,2.4140805364413698,-1.1134097681064297,-0.03201238316427893,-0.6870983502389405,-0.18810946914769616,-0.4498143273913549,-0.8728750171589886,-0.6342192735405214,-0.819682822993657,0.1234239573228073,1.4211029662479921,1.5713097730015686,-0.5287189651896583,-0.4235539786397383,-0.7931210294366591,-0.5023966694843781,-0.006061144709344608,-0.5287189651896583,3.919014730047917,-1.086586487466602,-0.4498143273913549,-0.3448944504989137,-0.7931210294366591,-0.6342192735405214,-0.29255459388450233,0.6115555906448871,-0.6342192735405214,-0.1620462766525934,-0.1620462766525934,2.5859395556139195,1.0687366974464951,2.806129116763043,-0.47609517429475745,1.119241145820181,0.5092850756510509,-0.47609517429475745,1.0181752334237035,1.1948922097827732,1.8703440739483437 | 3,246 |
Abnormal heart valve morphology | 15 | 75 | 2.177512 | 0.029442 | Q9UHX1,P51798,P16278,P10644,Q8NCH0,Q96PU5,P04062,P06753,Q9BXW9,O95155,Q92889,O75431,O96028,P51812,O75844 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 0,251,33,222,230,200,76,336,240,244,316,248,213,279,190 | 1657,2990,1567,704,2334,2718,2041,248,190,244,1501,213,790,1385,76,370,336,1445,2725,222,33,2775,1032,2843,2206,2055,1328,1979,1034,1900,3083,251,279,798,2210,1128,1846,634,2471,583,2213,2473,2624,756,1041,1762,1191,716,2679,1926,1856,681,1096,1288,768,2741,428,1348,1290,562,230,811,316,2543,200,2370,240,1067,2513,1560,0,2654,2182,786,701 | -0.18810946914769616,-0.819682822993657,-0.1620462766525934,0.3039647528659509,-0.4235539786397383,-0.6078122100368903,-0.31871463345796447,1.1696891723387541,1.4962652266439553,1.1948922097827732,-0.1360020577956454,1.3458212477032034,0.25246773267811196,-0.08397003066656783,2.732827412432188,0.739040326321,0.8407522538471938,-0.10997668458835863,-0.6078122100368903,1.2955661860369987,3.7268890651643467,-0.6342192735405214,0.09756269387250471,-0.6870983502389405,-0.3710941852773667,-0.31871463345796447,-0.05798197126028844,-0.29255459388450233,0.09756269387250471,-0.2664141933665721,-0.9528376270712595,1.1696891723387541,1.0687366974464951,0.25246773267811196,-0.3710941852773667,0.04578676244131425,-0.24029329531427543,0.38108381849412826,-0.47609517429475745,0.43241340517931676,-0.3710941852773667,-0.47609517429475745,-0.5550622157783601,0.27822474270062764,0.09756269387250471,-0.21419176492469524,0.019871864265687718,0.3039647528659509,-0.5814265778010619,-0.2664141933665721,-0.24029329531427543,0.32968786719872717,0.07168366704405241,-0.03201238316427893,0.27822474270062764,-0.6078122100368903,0.6370836521056745,-0.05798197126028844,-0.03201238316427893,0.4580535594777235,1.2704182773309,0.25246773267811196,0.91687882319615,-0.5023966694843781,1.4461702390450293,-0.4235539786397383,1.2200813591990216,0.09756269387250471,-0.47609517429475745,-0.1360020577956454,8.366255129812147,-0.5550622157783601,-0.3448944504989137,0.27822474270062764,0.32968786719872717 | 3,246 |
Limb ataxia | 10 | 26 | 2.17726 | 0.029461 | Q8IV08,Q14108,P04080,Q13501,Q10713,O75298,P07196,P04062,P41440,Q9NR77 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 164,4,289,427,170,168,327,76,108,180 | 2955,702,2522,3079,168,76,289,327,1388,2198,2128,2410,2777,108,170,427,4,164,2159,2914,890,1303,180,478,2328,1070 | -0.7931210294366591,0.3039647528659509,-0.5023966694843781,-0.9528376270712595,1.646238301853119,2.732827412432188,1.0181752334237035,0.8661426282602883,-0.08397003066656783,-0.3710941852773667,-0.3448944504989137,-0.4498143273913549,-0.6342192735405214,2.2416791937316303,1.646238301853119,0.6370836521056745,5.4604731281181715,1.6961270173061391,-0.3448944504989137,-0.7400651437154296,0.2009022908471458,-0.03201238316427893,1.5962987576738683,0.5604521702536023,-0.39731397995833206,0.09756269387250471 | 3,246 |
Golgi vesicle transport | 33 | 134 | 2.171148 | 0.02992 | P24390,Q12907,Q15334,Q9Y6B6,Q96PC5,O60499,Q9Y282,O14828,P49257,Q92572,Q13445,P35606,O15127,Q15437,Q9Y3B3,O14617,O00471,O15260,P84085,O43617,Q99523,Q92614,P18085,Q96JB2,P40616,Q13439,Q8TBA6,O95487,Q8TAG9,Q9P2W9,Q9UBV8,Q8TD16,Q4J6C6 | Processes and pathways | GO Biological process | msigdb_gobp | 2,385,386,548,544,395,22,394,278,415,162,300,421,177,576,553,550,63,72,446,209,340,88,347,343,470,492,350,231,242,380,519,371 | 2713,550,2808,703,553,394,977,1162,624,421,2187,63,978,2040,446,1665,1816,1820,395,942,1440,3133,1379,2610,1961,2525,827,2046,1964,350,2459,2047,791,88,1177,2,300,1447,343,2572,1080,2134,1980,1331,606,278,796,658,2417,1083,1036,2286,2062,2210,1186,2064,1907,2212,1334,2068,1335,2071,1688,3023,1039,72,756,843,385,3176,1765,1043,470,162,1287,1194,1857,386,638,763,177,371,2223,769,2006,1295,1543,2946,1049,1353,231,492,519,2095,851,415,340,1301,2436,347,1209,855,544,1012,209,1795,1017,858,1065,969,2650,2104,1556,596,1158,1646,2515,242,1068,380,1649,785,3052,1217,22,2116,1369,863,576,2559,1372,548,701,824 | -0.6078122100368903,0.4580535594777235,-0.6606479316905032,0.3039647528659509,0.4580535594777235,0.6880929270902055,0.1234239573228073,0.019871864265687718,0.38108381849412826,0.6370836521056745,-0.3710941852773667,3.074111943417051,0.1234239573228073,-0.31871463345796447,0.5860117936562828,-0.18810946914769616,-0.24029329531427543,-0.24029329531427543,0.6880929270902055,0.14926757041348834,-0.10997668458835863,-1.086586487466602,-0.08397003066656783,-0.5550622157783601,-0.29255459388450233,-0.5023966694843781,0.22669361755482975,-0.31871463345796447,-0.29255459388450233,0.7899265425128388,-0.47609517429475745,-0.31871463345796447,0.25246773267811196,2.5859395556139195,0.019871864265687718,7.063640679323355,0.9928729317279787,-0.10997668458835863,0.8153469194562949,-0.5287189651896583,0.07168366704405241,-0.3448944504989137,-0.29255459388450233,-0.05798197126028844,0.40675685759510555,1.0687366974464951,0.25246773267811196,0.355394188525345,-0.4498143273913549,0.07168366704405241,0.09756269387250471,-0.39731397995833206,-0.31871463345796447,-0.3710941852773667,0.019871864265687718,-0.31871463345796447,-0.2664141933665721,-0.3710941852773667,-0.05798197126028844,-0.31871463345796447,-0.05798197126028844,-0.31871463345796447,-0.18810946914769616,-0.8462674242732842,0.09756269387250471,2.806129116763043,0.27822474270062764,0.22669361755482975,0.7135743175341883,-1.3018851715713253,-0.21419176492469524,0.09756269387250471,0.5604521702536023,1.6961270173061391,-0.03201238316427893,0.019871864265687718,-0.24029329531427543,0.7135743175341883,0.38108381849412826,0.27822474270062764,1.5962987576738683,0.739040326321,-0.3710941852773667,0.27822474270062764,-0.29255459388450233,-0.03201238316427893,-0.1360020577956454,-0.7665818624827188,0.09756269387250471,-0.05798197126028844,1.2704182773309,0.5348766285518468,0.5092850756510509,-0.31871463345796447,0.22669361755482975,0.6625960679420675,0.8407522538471938,-0.03201238316427893,-0.4498143273913549,0.8153469194562949,0.019871864265687718,0.22669361755482975,0.4836774176196852,0.1234239573228073,1.3960224207311585,-0.21419176492469524,0.1234239573228073,0.22669361755482975,0.09756269387250471,0.14926757041348834,-0.5550622157783601,-0.31871463345796447,-0.1360020577956454,0.43241340517931676,0.04578676244131425,-0.1620462766525934,-0.47609517429475745,1.2200813591990216,0.09756269387250471,0.739040326321,-0.1620462766525934,0.27822474270062764,-0.8728750171589886,0.019871864265687718,4.1105797954064025,-0.31871463345796447,-0.05798197126028844,0.22669361755482975,0.4580535594777235,-0.5023966694843781,-0.05798197126028844,0.4836774176196852,0.32968786719872717,0.25246773267811196 | 3,246 |
Secretory granule membrane | 25 | 73 | 2.169216 | 0.030066 | O00462,P42785,P30519,Q08722,P11717,O15439,P10253,Q08431,P10321,O15260,P07602,P46940,Q9NZJ7,Q8NHP6,Q14165,Q9NQX7,Q93050,O00264,Q9BXS5,Q92542,Q07065,Q8NF37,P15291,P27105,Q15363 | Localization | GO Cellular component | msigdb_gocc | 503,7,14,537,397,296,298,314,434,63,65,317,598,454,584,211,85,578,618,614,235,491,362,238,638 | 2713,578,503,624,63,296,2262,1029,2042,2956,745,1825,1826,873,790,65,298,434,791,397,362,3154,985,1177,238,14,1591,1977,2279,2207,7,317,796,1844,1454,1036,2286,2067,2068,1335,2070,2473,714,2475,3155,1921,235,314,537,1132,762,584,1004,638,3026,2152,1469,2088,491,454,614,85,1475,691,1634,618,3033,1876,211,598,1646,1491,1024 | -0.6078122100368903,0.43241340517931676,0.5092850756510509,0.38108381849412826,3.074111943417051,0.9928729317279787,-0.39731397995833206,0.09756269387250471,-0.31871463345796447,-0.7931210294366591,0.27822474270062764,-0.24029329531427543,-0.24029329531427543,0.2009022908471458,0.25246773267811196,3.049800312599363,0.9928729317279787,0.6115555906448871,0.25246773267811196,0.6880929270902055,0.7644910395751178,-1.167131539845109,0.1234239573228073,0.019871864265687718,1.2200813591990216,4.70576711199326,-0.1620462766525934,-0.29255459388450233,-0.39731397995833206,-0.3710941852773667,5.248982947695327,0.8915181244165605,0.25246773267811196,-0.24029329531427543,-0.10997668458835863,0.09756269387250471,-0.39731397995833206,-0.31871463345796447,-0.31871463345796447,-0.05798197126028844,-0.31871463345796447,-0.47609517429475745,0.3039647528659509,-0.47609517429475745,-1.167131539845109,-0.2664141933665721,1.2452566916042276,0.91687882319615,0.4836774176196852,0.04578676244131425,0.27822474270062764,0.43241340517931676,0.1234239573228073,0.38108381849412826,-0.8462674242732842,-0.3448944504989137,-0.10997668458835863,-0.31871463345796447,0.5348766285518468,0.5860117936562828,0.40675685759510555,2.634944712077862,-0.10997668458835863,0.32968786719872717,-0.1620462766525934,0.40675685759510555,-0.8462674242732842,-0.24029329531427543,1.3709285366908623,0.43241340517931676,-0.1620462766525934,-0.10997668458835863,0.1234239573228073 | 3,246 |
Class i mhc mediated antigen processing presentation | 20 | 115 | 2.16619 | 0.030297 | P55786,P49721,Q9BSL1,Q9UL46,P28070,Q9UBS8,Q9NZ08,P20618,P61289,O00231,P28072,P10321,Q9UJX2,Q96PU5,P19474,P28074,P46934,O95487,P60900,Q9UIQ6 | Processes and pathways | Reactome Pathways | msigdb_reactome | 3,5,267,406,142,155,35,290,408,304,184,434,462,200,77,224,225,350,114,119 | 2037,2713,304,3054,1315,1959,976,1163,742,1379,654,628,1823,2525,2664,1964,350,790,711,1174,434,1325,77,290,2274,1230,1179,1832,2203,2204,2052,1589,142,184,224,1510,2616,1233,2730,2619,225,1515,676,5,1083,1983,1037,2210,1847,3,2934,114,1755,1238,635,408,1520,840,1130,2355,1457,1759,1131,758,957,2678,1467,2144,1194,1093,2294,449,585,1698,845,1619,3001,1620,763,1245,2151,2152,2490,1347,2908,1865,2093,1791,1207,1868,2500,200,617,1940,267,1423,1303,1482,35,1728,155,119,462,784,1214,2032,406,2114,2328,2557,2865,649,1810,548,1656 | -0.31871463345796447,-0.6078122100368903,0.9675561480174244,-0.899505788360606,-0.05798197126028844,-0.29255459388450233,0.1234239573228073,0.019871864265687718,0.27822474270062764,-0.08397003066656783,0.355394188525345,0.38108381849412826,-0.24029329531427543,-0.5023966694843781,-0.5814265778010619,-0.29255459388450233,0.7899265425128388,0.25246773267811196,0.3039647528659509,0.019871864265687718,0.6115555906448871,-0.05798197126028844,2.732827412432188,1.0181752334237035,-0.39731397995833206,-0.006061144709344608,0.019871864265687718,-0.24029329531427543,-0.3710941852773667,-0.3710941852773667,-0.31871463345796447,-0.1620462766525934,1.8951830310030808,1.5463078978712268,1.2955661860369987,-0.1360020577956454,-0.5550622157783601,-0.006061144709344608,-0.6078122100368903,-0.5550622157783601,1.2955661860369987,-0.1360020577956454,0.32968786719872717,5.413525936075921,0.07168366704405241,-0.29255459388450233,0.09756269387250471,-0.3710941852773667,-0.24029329531427543,5.788310865118061,-0.7665818624827188,2.167622859137434,-0.21419176492469524,-0.006061144709344608,0.38108381849412826,0.6625960679420675,-0.1360020577956454,0.22669361755482975,0.04578676244131425,-0.4235539786397383,-0.10997668458835863,-0.21419176492469524,0.04578676244131425,0.27822474270062764,0.14926757041348834,-0.5814265778010619,-0.10997668458835863,-0.3448944504989137,0.019871864265687718,0.07168366704405241,-0.39731397995833206,0.5860117936562828,0.43241340517931676,-0.18810946914769616,0.22669361755482975,-0.1620462766525934,-0.819682822993657,-0.1620462766525934,0.27822474270062764,-0.006061144709344608,-0.3448944504989137,-0.3448944504989137,-0.47609517429475745,-0.05798197126028844,-0.7400651437154296,-0.24029329531427543,-0.31871463345796447,-0.21419176492469524,0.019871864265687718,-0.24029329531427543,-0.47609517429475745,1.4461702390450293,0.40675685759510555,-0.2664141933665721,1.119241145820181,-0.08397003066656783,-0.03201238316427893,-0.10997668458835863,3.7028331681230524,-0.18810946914769616,1.7708658304290625,2.1429143813660745,0.5860117936562828,0.27822474270062764,0.019871864265687718,-0.29255459388450233,0.6880929270902055,-0.31871463345796447,-0.39731397995833206,-0.5023966694843781,-0.6870983502389405,0.38108381849412826,-0.21419176492469524,0.4836774176196852,-0.1620462766525934 | 3,246 |
Negative regulation of response to external stimulus | 7 | 50 | 2.160155 | 0.030761 | P04062,P19474,P28070,P80303,Q96G23,O43657,Q9UMX5 | Processes and pathways | GO Biological process | msigdb_gobp | 76,77,142,16,113,48,87 | 2607,1663,48,744,2044,2264,629,351,790,76,711,2768,2402,580,511,947,77,1230,142,1676,1396,2413,2352,1084,2578,1906,3211,16,1918,515,1002,1858,516,372,1785,1009,172,2235,2543,2857,113,2500,1360,616,2591,3104,861,87,1160,1222 | -0.5550622157783601,-0.18810946914769616,3.2682504863299298,0.27822474270062764,-0.31871463345796447,-0.39731397995833206,0.38108381849412826,0.7899265425128388,0.25246773267811196,2.732827412432188,0.3039647528659509,-0.6342192735405214,-0.4498143273913549,0.43241340517931676,0.5092850756510509,0.14926757041348834,2.732827412432188,-0.006061144709344608,1.8951830310030808,-0.18810946914769616,-0.08397003066656783,-0.4498143273913549,-0.4235539786397383,0.07168366704405241,-0.5287189651896583,-0.2664141933665721,-1.6828394367657349,4.468304578365973,-0.2664141933665721,0.5092850756510509,0.1234239573228073,-0.24029329531427543,0.5092850756510509,0.739040326321,-0.21419176492469524,0.1234239573228073,1.646238301853119,-0.3710941852773667,-0.5023966694843781,-0.6870983502389405,2.2170052153908957,-0.47609517429475745,-0.05798197126028844,0.40675685759510555,-0.5287189651896583,-0.9795390827213797,0.22669361755482975,2.6104474870322045,0.04578676244131425,0.019871864265687718 | 3,246 |
Carboxypeptidase activity | 6 | 12 | 2.157682 | 0.030953 | P42785,P10619,Q96KP4,Q9H3G5,Q9HB40,O75976 | Functions | GO Molecular function | msigdb_gomf | 7,199,473,313,57,342 | 342,199,1322,3041,2930,7,1093,489,473,1634,313,57 | 0.8153469194562949,1.4461702390450293,-0.05798197126028844,-0.8728750171589886,-0.7665818624827188,5.248982947695327,0.07168366704405241,0.5348766285518468,0.5604521702536023,-0.1620462766525934,0.9422248046510306,3.195521831934781 | 3,246 |
Juvenile onset | 12 | 45 | 2.154851 | 0.031173 | P51798,P16278,O15118,P04080,P07196,Q16531,P41440,Q13510,P06753,Q9NR77,P54802,Q14566 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 251,33,131,289,327,204,108,272,336,180,217,60 | 2522,131,626,2121,1385,289,370,336,327,33,1831,512,1447,3230,3060,1749,108,1397,837,2621,1453,658,2353,251,217,1608,1285,1920,717,272,1343,60,204,561,3199,771,1300,1101,3033,1483,1154,2024,180,2031,1436 | -0.5023966694843781,1.994418108265382,0.38108381849412826,-0.3448944504989137,-0.08397003066656783,1.0181752334237035,0.739040326321,0.8407522538471938,0.8661426282602883,3.7268890651643467,-0.24029329531427543,0.5092850756510509,-0.10997668458835863,-2.1814737775608597,-0.899505788360606,-0.21419176492469524,2.2416791937316303,-0.08397003066656783,0.22669361755482975,-0.5550622157783601,-0.10997668458835863,0.355394188525345,-0.4235539786397383,1.1696891723387541,1.3207004867153997,-0.1620462766525934,-0.03201238316427893,-0.2664141933665721,0.3039647528659509,1.0939960112015843,-0.05798197126028844,3.0984136398458118,1.4211029662479921,0.4580535594777235,-1.5461400051345588,0.27822474270062764,-0.03201238316427893,0.07168366704405241,-0.8462674242732842,-0.10997668458835863,0.04578676244131425,-0.29255459388450233,1.5962987576738683,-0.29255459388450233,-0.08397003066656783 | 3,246 |
Cellular ion homeostasis | 18 | 84 | 2.153523 | 0.031278 | Q7L0J3,P50897,P09601,Q15334,P52306,O76024,Q96PU5,O43819,Q9HD20,P0DP25,O75503,P78417,Q93050,Q9Y487,Q8NEW0,Q8N511,P62942,Q9Y3D6 | Processes and pathways | GO Biological process | msigdb_gobp | 96,66,98,386,384,382,200,360,51,277,82,281,85,122,28,188,286,358 | 1659,1025,553,2391,360,2262,626,82,2263,3081,382,1501,2046,1076,1387,1320,1172,830,3105,2402,2048,1174,98,2769,277,1891,1673,1970,1031,1176,947,948,2407,2729,3057,2204,1181,2843,1591,1276,2134,66,1454,1083,992,384,2622,1084,2903,534,286,281,3112,1131,2000,386,1532,803,96,2232,413,188,1351,28,1628,774,85,642,2544,2499,200,3147,1719,1152,51,1154,2517,1730,901,1651,358,122,1070,2560 | -0.18810946914769616,0.09756269387250471,0.4580535594777235,-0.4498143273913549,0.7644910395751178,-0.39731397995833206,0.38108381849412826,2.634944712077862,-0.39731397995833206,-0.9528376270712595,0.7135743175341883,-0.1360020577956454,-0.31871463345796447,0.07168366704405241,-0.08397003066656783,-0.05798197126028844,0.019871864265687718,0.22669361755482975,-1.0062644931084461,-0.4498143273913549,-0.31871463345796447,0.019871864265687718,2.3402615879978588,-0.6342192735405214,1.0687366974464951,-0.2664141933665721,-0.18810946914769616,-0.29255459388450233,0.09756269387250471,0.019871864265687718,0.14926757041348834,0.14926757041348834,-0.4498143273913549,-0.6078122100368903,-0.899505788360606,-0.3710941852773667,0.019871864265687718,-0.6870983502389405,-0.1620462766525934,-0.03201238316427893,-0.3448944504989137,2.8793375078697796,-0.10997668458835863,0.07168366704405241,0.1234239573228073,0.7135743175341883,-0.5550622157783601,0.07168366704405241,-0.7400651437154296,0.4836774176196852,1.0434631299656707,1.0687366974464951,-1.0330140600804507,0.04578676244131425,-0.29255459388450233,0.7135743175341883,-0.1360020577956454,0.25246773267811196,2.389485348920194,-0.3710941852773667,0.6625960679420675,1.5212930700276128,-0.05798197126028844,3.8470341251685394,-0.1620462766525934,0.27822474270062764,2.634944712077862,0.38108381849412826,-0.5023966694843781,-0.47609517429475745,1.4461702390450293,-1.1134097681064297,-0.18810946914769616,0.04578676244131425,3.2682504863299298,0.04578676244131425,-0.47609517429475745,-0.18810946914769616,0.2009022908471458,-0.1620462766525934,0.7899265425128388,2.118194303237033,0.09756269387250471,-0.5023966694843781 | 3,246 |
EF-hand domain pair [IPR011992] | 14 | 52 | 2.152484 | 0.031359 | O75071,P41208,Q9BRK5,Q96AY3,Q99584,Q14257,P80303,Q9UBV8,Q9NWM8,O43852,P0DP25,P35609,Q02818,Q8IYU8 | Sequence | InterPro Superfamily | interpro_homologous_superfamily | 258,34,260,99,496,106,16,380,118,189,277,469,27,413 | 1165,652,189,258,3133,1380,1501,1388,277,1122,2771,2345,3056,947,1591,1593,469,34,1080,2414,581,1188,1754,16,2733,27,3233,1092,106,2973,1770,2741,1625,1707,2429,413,1472,491,99,1938,496,1719,260,1064,2758,1258,118,3131,782,380,1312,1217 | 0.019871864265687718,0.355394188525345,1.4962652266439553,1.14447217515618,-1.086586487466602,-0.08397003066656783,-0.1360020577956454,-0.08397003066656783,1.0687366974464951,0.04578676244131425,-0.6342192735405214,-0.4235539786397383,-0.899505788360606,0.14926757041348834,-0.1620462766525934,-0.1620462766525934,0.5604521702536023,3.7268890651643467,0.07168366704405241,-0.4498143273913549,0.43241340517931676,0.019871864265687718,-0.21419176492469524,4.468304578365973,-0.6078122100368903,3.8470341251685394,-2.2655750573285,0.07168366704405241,2.266341771441869,-0.7931210294366591,-0.21419176492469524,-0.6078122100368903,-0.1620462766525934,-0.18810946914769616,-0.4498143273913549,0.6625960679420675,-0.10997668458835863,0.5348766285518468,2.3156329202480475,-0.2664141933665721,0.5348766285518468,-0.18810946914769616,1.14447217515618,0.09756269387250471,-0.6078122100368903,-0.006061144709344608,2.1429143813660745,-1.059787988728998,0.27822474270062764,0.739040326321,-0.03201238316427893,0.019871864265687718 | 3,246 |
Inorganic anion transport | 8 | 23 | 2.151083 | 0.03147 | P51798,Q9UHG3,O15439,P54105,Q9UBX3,P21796,P08183,P45880 | Processes and pathways | GO Biological process | msigdb_gobp | 251,103,296,174,143,53,250,31 | 1314,296,706,250,2769,53,31,992,251,174,1084,1991,1404,3026,3219,1251,2502,390,1018,143,103,1111,2560 | -0.05798197126028844,0.9928729317279787,0.3039647528659509,1.1696891723387541,-0.6342192735405214,3.219774416782617,3.7990028619728236,0.1234239573228073,1.1696891723387541,1.6212749135794295,0.07168366704405241,-0.29255459388450233,-0.08397003066656783,-0.8462674242732842,-1.8755094393685137,-0.006061144709344608,-0.47609517429475745,0.7135743175341883,0.1234239573228073,1.8951830310030808,2.290992997439851,0.07168366704405241,-0.5023966694843781 | 3,246 |
Endoplasmic reticulum to golgi vesicle mediated transport | 16 | 69 | 2.150858 | 0.031487 | P24390,Q12907,Q13445,O95487,O43617,P35606,Q9P2W9,Q9Y6B6,Q15437,Q9Y3B3,Q96PC5,Q9UBV8,Q9Y282,P18085,Q96JB2,P49257 | Processes and pathways | GO Biological process | msigdb_gobp | 2,385,162,350,446,300,242,548,177,576,544,380,22,88,347,278 | 2808,703,1162,978,2040,446,1440,3133,1379,2525,827,2046,1964,350,88,2,300,1331,278,796,1083,1036,2286,2062,2210,2064,1334,1688,843,385,1043,162,1194,638,763,177,2223,769,2006,1295,1353,2095,851,1301,2436,347,544,1017,858,969,2650,2104,1556,596,1158,1646,242,1068,380,1649,22,2116,1369,863,576,2559,1372,548,824 | -0.6606479316905032,0.3039647528659509,0.019871864265687718,0.1234239573228073,-0.31871463345796447,0.5860117936562828,-0.10997668458835863,-1.086586487466602,-0.08397003066656783,-0.5023966694843781,0.22669361755482975,-0.31871463345796447,-0.29255459388450233,0.7899265425128388,2.5859395556139195,7.063640679323355,0.9928729317279787,-0.05798197126028844,1.0687366974464951,0.25246773267811196,0.07168366704405241,0.09756269387250471,-0.39731397995833206,-0.31871463345796447,-0.3710941852773667,-0.31871463345796447,-0.05798197126028844,-0.18810946914769616,0.22669361755482975,0.7135743175341883,0.09756269387250471,1.6961270173061391,0.019871864265687718,0.38108381849412826,0.27822474270062764,1.5962987576738683,-0.3710941852773667,0.27822474270062764,-0.29255459388450233,-0.03201238316427893,-0.05798197126028844,-0.31871463345796447,0.22669361755482975,-0.03201238316427893,-0.4498143273913549,0.8153469194562949,0.4836774176196852,0.1234239573228073,0.22669361755482975,0.14926757041348834,-0.5550622157783601,-0.31871463345796447,-0.1360020577956454,0.43241340517931676,0.04578676244131425,-0.1620462766525934,1.2200813591990216,0.09756269387250471,0.739040326321,-0.1620462766525934,4.1105797954064025,-0.31871463345796447,-0.05798197126028844,0.22669361755482975,0.4580535594777235,-0.5023966694843781,-0.05798197126028844,0.4836774176196852,0.25246773267811196 | 3,246 |
Cdt1 association with the cdc6 orc origin complex | 9 | 41 | 2.144002 | 0.032033 | P20618,P49721,Q9Y619,Q9UL46,P28070,P60900,O00231,P28072,P28074 | Processes and pathways | Reactome Pathways | msigdb_reactome | 290,5,303,406,142,114,304,184,224 | 304,3054,1315,1959,742,1817,654,1325,290,1230,1179,1832,2203,1589,142,184,224,2730,2619,1515,676,5,1983,1847,114,408,840,1130,2355,758,957,585,1698,1791,617,1940,1254,932,406,2557,303 | 0.9675561480174244,-0.899505788360606,-0.05798197126028844,-0.29255459388450233,0.27822474270062764,-0.24029329531427543,0.355394188525345,-0.05798197126028844,1.0181752334237035,-0.006061144709344608,0.019871864265687718,-0.24029329531427543,-0.3710941852773667,-0.1620462766525934,1.8951830310030808,1.5463078978712268,1.2955661860369987,-0.6078122100368903,-0.5550622157783601,-0.1360020577956454,0.32968786719872717,5.413525936075921,-0.29255459388450233,-0.24029329531427543,2.167622859137434,0.6625960679420675,0.22669361755482975,0.04578676244131425,-0.4235539786397383,0.27822474270062764,0.14926757041348834,0.43241340517931676,-0.18810946914769616,-0.21419176492469524,0.40675685759510555,-0.2664141933665721,-0.006061144709344608,0.1750936448097422,0.6880929270902055,-0.5023966694843781,0.9928729317279787 | 3,246 |
Proteasome degradation | 10 | 42 | 2.140355 | 0.032326 | P61289,P20618,P49721,Q9UL46,P28070,P60900,O00231,P28072,P28074,P46934 | Processes and pathways | WikiPathways | msigdb_wp | 408,290,5,406,142,114,304,184,224,225 | 304,3054,1959,742,654,790,711,1171,1443,434,2271,1325,290,2274,1230,1179,1832,2203,1589,142,184,224,2730,2619,225,1515,676,5,1983,1847,114,408,840,1130,2355,758,957,1698,617,1940,406,2557 | 0.9675561480174244,-0.899505788360606,-0.29255459388450233,0.27822474270062764,0.355394188525345,0.25246773267811196,0.3039647528659509,0.019871864265687718,-0.10997668458835863,0.6115555906448871,-0.39731397995833206,-0.05798197126028844,1.0181752334237035,-0.39731397995833206,-0.006061144709344608,0.019871864265687718,-0.24029329531427543,-0.3710941852773667,-0.1620462766525934,1.8951830310030808,1.5463078978712268,1.2955661860369987,-0.6078122100368903,-0.5550622157783601,1.2955661860369987,-0.1360020577956454,0.32968786719872717,5.413525936075921,-0.29255459388450233,-0.24029329531427543,2.167622859137434,0.6625960679420675,0.22669361755482975,0.04578676244131425,-0.4235539786397383,0.27822474270062764,0.14926757041348834,-0.18810946914769616,0.40675685759510555,-0.2664141933665721,0.6880929270902055,-0.5023966694843781 | 3,246 |
Signal sequence binding | 7 | 27 | 2.138394 | 0.032485 | P24390,Q15388,P40855,Q9UHB9,P52292,P50542,Q8TEX9 | Functions | GO Molecular function | msigdb_gomf | 2,259,227,368,44,270,144 | 502,2561,936,941,2719,1500,2,2056,1683,227,2575,270,44,1903,1753,1909,1520,1612,1136,2682,259,144,429,2590,2917,1486,368 | 0.5092850756510509,-0.5287189651896583,0.14926757041348834,0.14926757041348834,-0.6078122100368903,-0.1360020577956454,7.063640679323355,-0.31871463345796447,-0.18810946914769616,1.2704182773309,-0.5287189651896583,1.0939960112015843,3.340892378532978,-0.2664141933665721,-0.21419176492469524,-0.2664141933665721,-0.1360020577956454,-0.1620462766525934,0.04578676244131425,-0.5814265778010619,1.14447217515618,1.8703440739483437,0.6370836521056745,-0.5287189651896583,-0.7400651437154296,-0.10997668458835863,0.7644910395751178 | 3,246 |
Ion transport | 9 | 51 | 2.135716 | 0.032703 | P51798,P00846,P21281,O75964,P21796,Q93050,Q9Y487,Q8NEW0,P45880 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 251,101,337,210,53,85,122,28,31 | 1025,1314,2811,210,1501,509,101,1387,1320,830,2769,1031,948,337,2346,53,1229,1394,1448,1328,1276,31,3061,992,251,2622,1084,2783,952,2903,1344,1532,3026,3219,1251,518,1351,28,85,2502,1719,2702,390,1018,1426,2323,1730,1651,1111,122,2560 | 0.09756269387250471,-0.05798197126028844,-0.6606479316905032,1.3709285366908623,-0.1360020577956454,0.5092850756510509,2.290992997439851,-0.08397003066656783,-0.05798197126028844,0.22669361755482975,-0.6342192735405214,0.09756269387250471,0.14926757041348834,0.8407522538471938,-0.4235539786397383,3.219774416782617,-0.006061144709344608,-0.08397003066656783,-0.10997668458835863,-0.05798197126028844,-0.03201238316427893,3.7990028619728236,-0.899505788360606,0.1234239573228073,1.1696891723387541,-0.5550622157783601,0.07168366704405241,-0.6342192735405214,0.14926757041348834,-0.7400651437154296,-0.05798197126028844,-0.1360020577956454,-0.8462674242732842,-1.8755094393685137,-0.006061144709344608,0.5092850756510509,-0.05798197126028844,3.8470341251685394,2.634944712077862,-0.47609517429475745,-0.18810946914769616,-0.5814265778010619,0.7135743175341883,0.1234239573228073,-0.08397003066656783,-0.39731397995833206,-0.18810946914769616,-0.1620462766525934,0.07168366704405241,2.118194303237033,-0.5023966694843781 | 3,246 |
Ceramide metabolic process | 9 | 21 | 2.134885 | 0.03277 | O95470,P04062,Q16739,Q13510,Q96G23,Q8NCC3,P17900,P30153,P06280 | Processes and pathways | GO Biological process | msigdb_gobp | 326,76,78,272,113,52,214,435,370 | 741,2893,1073,326,76,370,2193,3105,214,909,1588,435,272,78,2487,52,113,2168,571,2106,464 | 0.27822474270062764,-0.7400651437154296,0.07168366704405241,0.8661426282602883,2.732827412432188,0.739040326321,-0.3710941852773667,-1.0062644931084461,1.3458212477032034,0.1750936448097422,-0.1620462766525934,0.6115555906448871,1.0939960112015843,2.732827412432188,-0.47609517429475745,3.244017289535622,2.2170052153908957,-0.3448944504989137,0.4580535594777235,-0.31871463345796447,0.5860117936562828 | 3,246 |
Oxidative phosphorylation | 14 | 57 | 2.134661 | 0.032789 | Q9Y487,P00846,O14949,P14406,O96000,Q9Y6M9,P21281,O75964,P00403,Q93050,Q86Y39,P22695,Q9UDW1,O43676 | Processes and pathways | KEGG Pathways | msigdb_kegg | 122,101,138,43,203,145,337,210,181,85,282,25,247,95 | 2606,1113,138,422,95,3143,1266,2841,1666,2394,2811,210,3039,2766,2997,203,181,101,830,2564,2343,832,484,43,2961,2528,749,337,2346,1228,25,1229,1394,3134,2410,2133,1448,1328,1276,3061,2782,1984,2783,952,2903,3074,1532,2787,1621,339,282,85,2373,247,1730,122,145 | -0.5550622157783601,0.04578676244131425,1.9200098581999967,0.6370836521056745,2.4140805364413698,-1.1134097681064297,-0.03201238316427893,-0.6870983502389405,-0.18810946914769616,-0.4498143273913549,-0.6606479316905032,1.3709285366908623,-0.8728750171589886,-0.6342192735405214,-0.819682822993657,1.4211029662479921,1.5713097730015686,2.290992997439851,0.22669361755482975,-0.5287189651896583,-0.4235539786397383,0.22669361755482975,0.5348766285518468,3.3650872278199344,-0.7931210294366591,-0.5023966694843781,0.27822474270062764,0.8407522538471938,-0.4235539786397383,-0.006061144709344608,3.919014730047917,-0.006061144709344608,-0.08397003066656783,-1.086586487466602,-0.4498143273913549,-0.3448944504989137,-0.10997668458835863,-0.05798197126028844,-0.03201238316427893,-0.899505788360606,-0.6342192735405214,-0.29255459388450233,-0.6342192735405214,0.14926757041348834,-0.7400651437154296,-0.9261599274787706,-0.1360020577956454,-0.6342192735405214,-0.1620462766525934,0.8407522538471938,1.0687366974464951,2.634944712077862,-0.4235539786397383,1.1948922097827732,-0.18810946914769616,2.118194303237033,1.8703440739483437 | 3,246 |
Signaling by notch4 | 9 | 43 | 2.125967 | 0.033506 | P20618,P49721,Q9UL46,P28070,P31749,P60900,O00231,P28072,P28074 | Processes and pathways | Reactome Pathways | msigdb_reactome | 290,5,406,142,363,114,304,184,224 | 304,3054,1315,1959,742,654,1325,290,1230,1179,1832,2203,1589,142,184,224,363,2730,2619,1515,676,5,1983,1847,114,408,840,1130,2355,955,1457,758,957,2080,1467,1698,1791,614,617,1940,406,2557,1374 | 0.9675561480174244,-0.899505788360606,-0.05798197126028844,-0.29255459388450233,0.27822474270062764,0.355394188525345,-0.05798197126028844,1.0181752334237035,-0.006061144709344608,0.019871864265687718,-0.24029329531427543,-0.3710941852773667,-0.1620462766525934,1.8951830310030808,1.5463078978712268,1.2955661860369987,0.7644910395751178,-0.6078122100368903,-0.5550622157783601,-0.1360020577956454,0.32968786719872717,5.413525936075921,-0.29255459388450233,-0.24029329531427543,2.167622859137434,0.6625960679420675,0.22669361755482975,0.04578676244131425,-0.4235539786397383,0.14926757041348834,-0.10997668458835863,0.27822474270062764,0.14926757041348834,-0.31871463345796447,-0.10997668458835863,-0.18810946914769616,-0.21419176492469524,0.40675685759510555,0.40675685759510555,-0.2664141933665721,0.6880929270902055,-0.5023966694843781,-0.05798197126028844 | 3,246 |
Ventricular hypertrophy | 13 | 37 | 2.123471 | 0.033714 | O00170,P23786,Q7LG56,O43772,P10253,O95630,P11047,O75431,P00403,P06280,Q9H9S5,P35609,O75844 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 465,329,373,13,298,361,396,248,181,370,419,469,190 | 465,13,248,190,2263,361,181,1385,370,298,396,1391,1893,1228,329,2410,2669,469,1328,2533,2571,1900,633,2577,515,1134,1998,1096,2741,1781,373,2231,1939,1717,1256,2596,419 | 0.5604521702536023,4.70576711199326,1.1696891723387541,1.4962652266439553,-0.39731397995833206,0.7644910395751178,1.5713097730015686,-0.08397003066656783,0.739040326321,0.9928729317279787,0.6880929270902055,-0.08397003066656783,-0.2664141933665721,-0.006061144709344608,0.8661426282602883,-0.4498143273913549,-0.5814265778010619,0.5604521702536023,-0.05798197126028844,-0.5023966694843781,-0.5287189651896583,-0.2664141933665721,0.38108381849412826,-0.5287189651896583,0.5092850756510509,0.04578676244131425,-0.29255459388450233,0.07168366704405241,-0.6078122100368903,-0.21419176492469524,0.739040326321,-0.3710941852773667,-0.2664141933665721,-0.18810946914769616,-0.006061144709344608,-0.5287189651896583,0.6625960679420675 | 3,246 |
Respiratory chain | 10 | 31 | 2.120276 | 0.033983 | Q96CU9,O14949,O96000,Q9Y6M9,P00403,Q86Y39,Q6DKK2,P22695,Q9UDW1,O43676 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 73,138,203,145,181,282,89,25,247,95 | 2606,138,422,95,3143,1266,2841,1666,2394,3039,2766,2997,203,181,2564,2961,2528,25,3134,2133,2782,1984,2787,1621,89,282,73,2513,295,247,145 | -0.5550622157783601,1.9200098581999967,0.6370836521056745,2.4140805364413698,-1.1134097681064297,-0.03201238316427893,-0.6870983502389405,-0.18810946914769616,-0.4498143273913549,-0.8728750171589886,-0.6342192735405214,-0.819682822993657,1.4211029662479921,1.5713097730015686,-0.5287189651896583,-0.7931210294366591,-0.5023966694843781,3.919014730047917,-1.086586487466602,-0.3448944504989137,-0.6342192735405214,-0.29255459388450233,-0.6342192735405214,-0.1620462766525934,2.5859395556139195,1.0687366974464951,2.806129116763043,-0.47609517429475745,1.0181752334237035,1.1948922097827732,1.8703440739483437 | 3,246 |
Copi dependent golgi to er retrograde traffic | 6 | 52 | 2.110848 | 0.034785 | O15260,P24390,P84085,P35606,Q9P2W9,P18085 | Processes and pathways | Reactome Pathways | msigdb_reactome | 63,2,72,300,242,88 | 2038,703,63,2040,1819,1379,1319,1963,510,88,2,949,300,1980,1331,796,912,2286,2062,1186,2071,1688,1690,72,1761,1087,1132,1765,1044,2974,638,769,1049,2910,851,2694,2697,1795,646,2173,1017,2593,1063,1018,858,349,1158,242,1068,576,1022,1372 | -0.31871463345796447,0.3039647528659509,3.074111943417051,-0.31871463345796447,-0.24029329531427543,-0.08397003066656783,-0.05798197126028844,-0.29255459388450233,0.5092850756510509,2.5859395556139195,7.063640679323355,0.14926757041348834,0.9928729317279787,-0.29255459388450233,-0.05798197126028844,0.25246773267811196,0.1750936448097422,-0.39731397995833206,-0.31871463345796447,0.019871864265687718,-0.31871463345796447,-0.18810946914769616,-0.18810946914769616,2.806129116763043,-0.21419176492469524,0.07168366704405241,0.04578676244131425,-0.21419176492469524,0.09756269387250471,-0.7931210294366591,0.38108381849412826,0.27822474270062764,0.09756269387250471,-0.7400651437154296,0.22669361755482975,-0.5814265778010619,-0.5814265778010619,-0.21419176492469524,0.38108381849412826,-0.3448944504989137,0.1234239573228073,-0.5287189651896583,0.09756269387250471,0.1234239573228073,0.22669361755482975,0.8153469194562949,0.04578676244131425,1.2200813591990216,0.09756269387250471,0.4580535594777235,0.1234239573228073,-0.05798197126028844 | 3,246 |
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