term
stringlengths
2
121
overlap
int64
6
281
setsize
int64
7
499
score
float64
1.96
10.6
pval
float64
0
0.05
edge
stringlengths
41
1.97k
type
stringclasses
5 values
subtype
stringclasses
24 values
subtype_key
stringclasses
24 values
edge_idxs
stringlengths
11
1.17k
ann_idxs
stringlengths
19
2.31k
ann_vals
stringlengths
124
9.94k
sig_size
int64
2.2k
3.73k
Ion transmembrane transporter activity
37
102
3.96167
0.000074
P55011,Q70HW3,O95563,Q96QD8,Q13423,O43681,O43808,P30825,Q8NEW0,P00846,O43772,P0CG08,P05023,O75964,Q9UDW1,Q9HC07,Q9Y6M7,Q93050,P06576,P98194,P21796,Q9H2D1,Q96S66,Q8TB61,Q9Y487,P00403,Q4KMQ2,P13073,Q9HD20,P45880,Q9NWR8,Q6P4Q7,Q9Y5K8,P16615,Q9UBX3,Q9C0H2,Q6P4A7
Functions
GO Molecular function
msigdb_gomf
508,3,504,396,10,518,519,274,412,32,280,541,540,39,41,171,172,46,433,571,185,66,329,461,74,324,598,335,89,350,250,362,516,241,121,249,122
1179,1987,518,280,519,971,1631,39,668,504,324,32,540,911,2734,433,2404,1565,2048,939,541,1632,1518,1713,335,241,1116,886,721,2906,185,591,2670,274,2804,2417,1571,2098,1295,1193,350,915,3268,1438,2141,2773,1051,508,1125,1574,919,3150,571,2713,1302,2190,10,2342,1129,1533,598,3336,2156,3176,122,362,3,1209,412,461,1658,1975,46,1592,1168,396,329,1139,693,1365,249,1982,66,3124,1928,1741,171,89,3196,250,121,41,877,1248,2927,1421,3012,74,516,855,2519,172
0.1539519038710691,-0.2624316007781427,0.7607227005345416,1.2398050154301583,0.7607227005345416,0.3034406273252866,-0.08515151713377264,3.294063684318148,0.5758696256500044,0.7810800557959103,1.1218400811435874,3.377301896133515,0.740329474853222,0.34578486103996076,-0.6725623413977179,0.9024811471197746,-0.4654794845873636,-0.04128507261807166,-0.28480032142736955,0.32463281965659274,0.740329474853222,-0.08515151713377264,-0.019418398789169906,-0.12919720072059518,1.1020654814306523,1.3566237550487579,0.1968694596042953,0.3668969742024014,0.5135820626533416,-0.8129792586013125,1.5679201137609433,0.6583941161256206,-0.6261830525123374,1.2593535158381115,-0.7191528925187254,-0.4654794845873636,-0.04128507261807166,-0.30721638022967535,0.08925988661092682,0.1539519038710691,1.0822579505106387,0.34578486103996076,-1.4203661597491495,0.02418316160624745,-0.3296800727932999,-0.6958310323456385,0.23962088616631888,0.7810800557959103,0.1968694596042953,-0.04128507261807166,0.34578486103996076,-1.0998392081028667,0.6994346651191702,-0.649346465031488,0.08925988661092682,-0.3521916978029156,4.0895286543280465,-0.4200172014503317,0.1968694596042953,-0.019418398789169906,0.6583941161256206,-1.9888702495275368,-0.3296800727932999,-1.148467709123556,1.9430943192648507,1.0624173267017085,5.649292040265413,0.1539519038710691,0.9426694105267227,0.8621544447614617,-0.08515151713377264,-0.24010992570608994,3.22711382314657,-0.04128507261807166,0.1754315665029435,0.9827206223582612,1.1218400811435874,0.1968694596042953,0.5551449816119026,0.06761072205801114,1.3372321800117861,-0.24010992570608994,2.7838210432391537,-1.051450154863121,-0.21783500662433905,-0.12919720072059518,1.6438632266775426,2.3433660052850382,-1.1973391736481231,1.3372321800117861,1.9615623146195156,3.2606290035101324,0.3879693798278019,0.13243023164297438,-0.8129792586013125,0.04591856434758408,-0.9076857627441651,2.5389712897634884,0.7810800557959103,0.4090022965830154,-0.5111409380756051,1.6438632266775426
3,381
Intrinsic component of organelle membrane
55
140
3.709216
0.000208
O95563,O60830,Q9Y287,P57105,Q9Y4W6,Q13505,Q8N8Q8,Q9Y282,Q15388,Q9NQC3,Q9NPA0,O43808,Q99595,P42892,Q96A33,Q12981,O95470,Q9BPX6,O14925,Q15125,O94901,Q8TCT9,O43752,Q8TB36,Q53H12,O95070,Q14739,Q86YN1,P98194,O15126,Q9Y5Y5,Q03518,Q86XL3,Q8TB61,Q6ZRP7,Q5HYI7,Q53S58,Q9UH99,Q9NX63,Q86UP2,Q15629,Q5T9L3,O75880,O75298,Q9Y2R0,Q9NWR8,P17152,Q9GZY8,O43292,O75844,P49069,Q9UG56,Q10471,Q8IWA4,Q6P4A7
Localization
GO Cellular component
msigdb_gocc
504,4,536,131,399,9,528,14,658,144,662,519,18,647,268,524,152,157,279,293,667,425,169,691,560,432,445,187,571,680,716,315,67,461,340,79,208,733,342,476,88,95,466,348,99,250,484,370,737,239,497,515,744,376,122
968,1843,1180,279,1468,1706,680,1329,737,997,169,519,2268,1988,4,348,1028,239,466,860,1942,667,432,152,504,1149,1847,1671,1517,1518,3346,484,1116,1897,1117,2280,942,2672,3200,647,497,1763,1395,1955,1298,1526,1126,131,1770,3150,571,2713,315,1960,744,524,9,2110,445,840,2501,2063,293,841,658,88,1778,1306,982,560,208,79,2986,2347,95,1588,122,1735,340,1268,476,67,1097,187,376,1134,2200,1589,528,1492,1209,691,461,3123,425,1065,1738,2542,820,268,1168,1874,1019,18,157,2114,776,1238,1498,1240,1462,370,1412,1741,1278,2388,662,144,1022,1245,250,342,1376,1419,1554,1555,2315,515,1625,733,2927,14,536,99,1422,808,399,2042,716,1142
0.3034406273252866,-0.1956065568925503,0.1539519038710691,1.2398050154301583,0.002404259502052453,-0.12919720072059518,0.5551449816119026,0.06761072205801114,0.4927433790687372,0.28220805924936154,1.6438632266775426,0.7607227005345416,-0.3973599555513764,-0.2624316007781427,4.919035001410219,1.0822579505106387,0.2609348885354999,1.3566237550487579,0.8419387390190867,0.3879693798278019,-0.24010992570608994,0.5758696256500044,0.9024811471197746,1.756913855622745,0.7810800557959103,0.1754315665029435,-0.1956065568925503,-0.10715181947123369,-0.019418398789169906,-0.019418398789169906,-2.1502718147921107,0.8216878926093156,0.1968694596042953,-0.21783500662433905,0.1968694596042953,-0.3973599555513764,0.32463281965659274,-0.6261830525123374,-1.221867139462494,0.5965566621544192,0.8014017254185795,-0.15128793340057795,0.04591856434758408,-0.24010992570608994,0.08925988661092682,-0.019418398789169906,0.1968694596042953,1.86895187853838,-0.15128793340057795,-1.0998392081028667,0.6994346651191702,-0.649346465031488,1.1612911271561115,-0.24010992570608994,0.4927433790687372,0.7607227005345416,4.10531535914725,-0.30721638022967535,0.8823351884307354,0.4090022965830154,-0.5111409380756051,-0.28480032142736955,1.220224679805845,0.4090022965830154,0.5965566621544192,2.3433660052850382,-0.15128793340057795,0.08925988661092682,0.3034406273252866,0.7199001923772445,1.4723284237534975,2.4504202205674956,-0.8839252917779894,-0.4200172014503317,2.271506265376009,-0.04128507261807166,1.9430943192648507,-0.12919720072059518,1.1020654814306523,0.11086630745425535,0.8419387390190867,2.7664794786953726,0.2182658209724741,1.5679201137609433,1.0226361470657186,0.1968694596042953,-0.3521916978029156,-0.04128507261807166,0.7607227005345416,0.002404259502052453,0.1539519038710691,0.5551449816119026,0.8621544447614617,-1.051450154863121,0.9225924964376042,0.23962088616631888,-0.12919720072059518,-0.5340471596998287,0.42999594114352935,1.2788703326571973,0.1754315665029435,-0.1956065568925503,0.28220805924936154,3.7862935365121144,1.700516799454386,-0.30721638022967535,0.47186627057669517,0.13243023164297438,0.002404259502052453,0.13243023164297438,0.02418316160624745,1.042543447000245,0.04591856434758408,-0.12919720072059518,0.11086630745425535,-0.44272360620966467,0.5965566621544192,1.8130577786414614,0.28220805924936154,0.13243023164297438,1.3372321800117861,1.1020654814306523,0.06761072205801114,0.04591856434758408,-0.019418398789169906,-0.019418398789169906,-0.3973599555513764,0.7810800557959103,-0.06319602389665722,0.5135820626533416,-0.8129792586013125,3.962619402550461,0.7607227005345416,2.235426922202329,0.04591856434758408,0.45095052821872006,0.9827206223582612,-0.2624316007781427,0.5343825284198839,0.1968694596042953
3,381
Mitochondrial transport
34
84
3.695114
0.00022
O60830,O60220,Q9Y5J7,Q9Y5J9,Q8N8Q8,Q15388,Q9NS69,Q99595,P49257,O14737,O00170,Q10713,Q96EK5,P00846,O43772,O14925,P52789,Q8N4H5,P30536,O75964,P55786,Q8TB36,Q53H12,P06576,O95429,O43464,P24539,O95831,P45880,Q14849,Q9GZY8,Q5JRX3,Q9UBX3,Q96QK1
Processes and pathways
GO Biological process
msigdb_gobp
4,380,272,273,528,658,16,18,649,150,517,523,153,32,280,279,542,37,40,39,48,691,560,433,683,314,591,219,350,360,370,368,121,637
2557,517,150,279,314,785,280,380,4,1028,2482,1631,39,1942,683,219,1149,32,1802,2734,433,1189,2487,3224,1518,2411,973,591,2670,3260,1995,40,2281,1571,3212,350,3268,649,704,1395,1298,542,48,1125,1574,2145,817,523,1911,360,2063,658,2012,1587,560,368,2156,2018,1134,2200,37,528,691,153,637,18,1546,2255,370,1878,1022,16,3325,1503,121,1883,1248,1837,2442,1935,2042,272,273,759
-0.5570041480733425,0.7607227005345416,1.756913855622745,1.2398050154301583,1.1612911271561115,0.45095052821872006,1.2398050154301583,1.0026952612052977,4.919035001410219,0.2609348885354999,-0.5111409380756051,-0.08515151713377264,3.294063684318148,-0.24010992570608994,0.5551449816119026,1.4146133989581882,0.1754315665029435,3.377301896133515,-0.17342429277519616,-0.6725623413977179,0.9024811471197746,0.1539519038710691,-0.5111409380756051,-1.2711098312889768,-0.019418398789169906,-0.4654794845873636,0.3034406273252866,0.6583941161256206,-0.6261830525123374,-1.3953280732566287,-0.2624316007781427,3.294063684318148,-0.3973599555513764,-0.04128507261807166,-1.2464572039127382,1.0822579505106387,-1.4203661597491495,0.5965566621544192,0.5343825284198839,0.04591856434758408,0.08925988661092682,0.740329474853222,3.2103258670728594,0.1968694596042953,-0.04128507261807166,-0.3296800727932999,0.42999594114352935,0.7607227005345416,-0.21783500662433905,1.0624173267017085,-0.28480032142736955,0.5965566621544192,-0.2624316007781427,-0.04128507261807166,0.7199001923772445,1.042543447000245,-0.3296800727932999,-0.2624316007781427,0.1968694596042953,-0.3521916978029156,3.3440660042253465,0.7607227005345416,0.5551449816119026,1.7381431283572701,0.6172062909671789,3.7862935365121144,-0.019418398789169906,-0.37475155706455276,1.042543447000245,-0.1956065568925503,0.28220805924936154,3.9466779732067017,-1.8303148472046438,0.002404259502052453,1.9615623146195156,-0.1956065568925503,0.13243023164297438,-0.17342429277519616,-0.4654794845873636,-0.21783500662433905,-0.2624316007781427,1.2788703326571973,1.2788703326571973,0.4927433790687372
3,381
Inner mitochondrial membrane protein complex
25
81
3.692313
0.000222
O60830,Q9Y5J7,Q13505,Q9Y4W6,P22695,P03886,Q99595,O14949,Q86Y39,Q9BPX6,P00846,O14925,O75964,Q9UDW1,P56556,Q8IYU8,P56378,O43676,P14406,P00403,Q5HYI7,Q9NX63,O96000,P13073,Q9NWR8
Localization
GO Cellular component
msigdb_gocc
4,272,9,399,139,15,18,147,287,157,32,279,39,41,435,176,305,58,61,324,79,342,334,335,250
2044,1987,279,147,606,58,4,2854,882,1431,1028,1604,1940,1631,39,786,2092,883,2929,334,324,32,15,433,939,2322,1632,1713,335,61,2567,1292,2905,886,1084,139,591,2670,3289,2569,2804,2134,1571,3200,915,3268,3273,2861,1125,305,1574,435,9,2780,2244,982,1587,560,79,1588,1735,287,176,1209,709,870,18,2253,157,1878,1245,250,2256,342,3325,41,2442,399,2042,272,967
-0.28480032142736955,-0.2624316007781427,1.2398050154301583,1.775656457586982,0.63781871017397,2.938901920174116,4.919035001410219,-0.765957559026696,0.3668969742024014,0.02418316160624745,0.2609348885354999,-0.06319602389665722,-0.24010992570608994,-0.08515151713377264,3.294063684318148,0.45095052821872006,-0.30721638022967535,0.3668969742024014,-0.8365724257127242,1.1020654814306523,1.1218400811435874,3.377301896133515,3.9466779732067017,0.9024811471197746,0.32463281965659274,-0.4200172014503317,-0.08515151713377264,-0.12919720072059518,1.1020654814306523,2.818437377950935,-0.5570041480733425,0.08925988661092682,-0.8129792586013125,0.3668969742024014,0.2182658209724741,1.8317167420126779,0.6583941161256206,-0.6261830525123374,-1.5211834842036118,-0.5570041480733425,-0.7191528925187254,-0.3296800727932999,-0.04128507261807166,-1.221867139462494,0.34578486103996076,-1.4203661597491495,-1.4454702271609903,-0.765957559026696,0.1968694596042953,1.1809678903438237,-0.04128507261807166,0.9024811471197746,4.10531535914725,-0.6958310323456385,-0.37475155706455276,0.3034406273252866,-0.04128507261807166,0.7199001923772445,2.4504202205674956,-0.04128507261807166,-0.12919720072059518,1.2398050154301583,1.6059499638802452,0.1539519038710691,0.5343825284198839,0.3879693798278019,3.7862935365121144,-0.37475155706455276,1.700516799454386,-0.1956065568925503,0.13243023164297438,1.3372321800117861,-0.37475155706455276,1.1020654814306523,-1.8303148472046438,3.2606290035101324,-0.4654794845873636,0.9827206223582612,-0.2624316007781427,1.2788703326571973,0.32463281965659274
3,381
Protein targeting
46
120
3.490131
0.000483
P40855,O60830,P57105,O60220,P31751,Q9Y5J7,Q9Y2T2,P46379,Q7L5D6,Q15388,Q9Y5J9,Q9NS69,O43681,Q99595,O60725,P49257,P50542,O00170,Q10713,O14737,P43307,Q9H9H4,O75381,O14925,Q8N4H5,P10909,P30536,Q13438,Q6ZWJ1,Q9UHB9,P55786,Q8TB36,Q53H12,Q15005,P33908,O95429,Q9Y5Y5,O43464,Q9Y5M8,O00159,Q15629,O95831,Q96RT1,O14964,Q9GZY8,Q5JRX3
Processes and pathways
GO Biological process
msigdb_gobp
259,4,131,380,7,272,138,11,660,658,273,16,518,18,19,649,650,517,523,150,30,677,161,279,37,166,40,423,561,697,48,691,560,688,53,683,716,314,198,700,88,219,621,605,370,368
700,2557,517,2359,2730,2173,150,279,605,314,785,518,970,380,19,4,161,2482,2091,1942,683,219,1149,1189,2405,1516,3224,166,813,3346,2411,1898,2049,3121,40,2832,7,1257,53,2281,2230,259,30,11,1119,649,1853,650,1955,1298,48,1526,131,3324,1769,2613,3150,1482,1339,1908,1200,2145,1302,523,2062,1579,1911,423,2421,688,2501,658,88,2012,726,1587,560,368,561,660,1015,1404,2018,1655,799,845,37,691,3068,2027,621,1019,1066,2589,18,2432,1546,2255,370,2884,677,1878,16,3325,1503,1377,697,2391,1883,3097,1934,138,1935,2041,2042,272,273,759,198,716
0.5343825284198839,-0.5570041480733425,0.7607227005345416,-0.44272360620966467,-0.6725623413977179,-0.3521916978029156,1.756913855622745,1.2398050154301583,0.63781871017397,1.1612911271561115,0.45095052821872006,0.7607227005345416,0.3034406273252866,1.0026952612052977,3.640406128534467,4.919035001410219,1.6816609462841285,-0.5111409380756051,-0.30721638022967535,-0.24010992570608994,0.5551449816119026,1.4146133989581882,0.1754315665029435,0.1539519038710691,-0.4654794845873636,-0.019418398789169906,-1.2711098312889768,1.6627764647279124,0.42999594114352935,-2.1502718147921107,-0.4654794845873636,-0.21783500662433905,-0.28480032142736955,-1.051450154863121,3.294063684318148,-0.7425282805304556,4.1682935038480915,0.11086630745425535,3.0922365590874046,-0.3973599555513764,-0.37475155706455276,1.2983556163200487,3.4104592394541533,4.073724975542204,0.1968694596042953,0.5965566621544192,-0.1956065568925503,0.5965566621544192,-0.24010992570608994,0.08925988661092682,3.2103258670728594,-0.019418398789169906,1.86895187853838,-1.8303148472046438,-0.15128793340057795,-0.5800122352625738,-1.0998392081028667,0.002404259502052453,0.06761072205801114,-0.21783500662433905,0.1539519038710691,-0.3296800727932999,0.08925988661092682,0.7607227005345416,-0.28480032142736955,-0.04128507261807166,-0.21783500662433905,0.9225924964376042,-0.4654794845873636,0.5551449816119026,-0.5111409380756051,0.5965566621544192,2.3433660052850382,-0.2624316007781427,0.5135820626533416,-0.04128507261807166,0.7199001923772445,1.042543447000245,0.7199001923772445,0.5965566621544192,0.28220805924936154,0.04591856434758408,-0.2624316007781427,-0.08515151713377264,0.45095052821872006,0.4090022965830154,3.3440660042253465,0.5551449816119026,-0.979308054094136,-0.2624316007781427,0.63781871017397,0.28220805924936154,0.23962088616631888,-0.5570041480733425,3.7862935365121144,-0.4654794845873636,-0.019418398789169906,-0.37475155706455276,1.042543447000245,-0.7894410947493521,0.5758696256500044,-0.1956065568925503,3.9466779732067017,-1.8303148472046438,0.002404259502052453,0.06761072205801114,0.5551449816119026,-0.44272360620966467,-0.1956065568925503,-1.0032971173184342,-0.21783500662433905,1.8503480686626494,-0.21783500662433905,-0.2624316007781427,-0.2624316007781427,1.2788703326571973,1.2788703326571973,0.4927433790687372,1.5297726164341399,0.5343825284198839
3,381
Protein localization
28
81
3.381082
0.000722
P40855,O60830,O60220,Q9Y5J7,Q13505,P46379,Q9Y5J9,Q9NS69,O43681,O43808,Q99595,Q13190,P51648,O75381,O14925,Q8N4H5,Q9NR77,Q13011,P06576,P21796,P09601,Q9NX63,O15254,Q15067,Q5JRX3,O00116,P49069,P50402
Processes and pathways
Reactome Pathways
msigdb_reactome
259,4,380,272,9,11,273,16,518,519,18,525,154,161,279,37,42,175,433,185,69,342,211,108,368,364,497,244
364,1250,279,1468,1382,211,785,518,970,519,380,4,161,3279,1028,2482,3078,971,3131,1942,1149,1082,433,939,1712,69,3224,1518,1713,1633,185,2182,2670,1719,3284,3200,259,11,497,244,650,2771,154,2140,1526,3324,2377,523,175,525,9,108,658,1587,368,1013,1817,660,1655,37,1541,691,2657,18,3207,2817,2310,1878,42,16,342,2512,3097,1248,2442,2517,2042,272,273,759,716
1.042543447000245,0.11086630745425535,1.2398050154301583,0.002404259502052453,0.04591856434758408,1.4531203598306963,0.45095052821872006,0.7607227005345416,0.3034406273252866,0.7607227005345416,1.0026952612052977,4.919035001410219,1.6816609462841285,-1.470640789074526,0.2609348885354999,-0.5111409380756051,-1.0032971173184342,0.3034406273252866,-1.07561496694313,-0.24010992570608994,0.1754315665029435,0.2182658209724741,0.9024811471197746,0.32463281965659274,-0.12919720072059518,2.6269341644334787,-1.2711098312889768,-0.019418398789169906,-0.12919720072059518,-0.08515151713377264,1.5679201137609433,-0.3521916978029156,-0.6261830525123374,-0.12919720072059518,-1.4958783657412849,-1.221867139462494,1.2983556163200487,4.073724975542204,0.8014017254185795,1.3372321800117861,0.5965566621544192,-0.6958310323456385,1.7193441514024306,-0.3296800727932999,-0.019418398789169906,-1.8303148472046438,-0.44272360620966467,0.7607227005345416,1.6059499638802452,0.7607227005345416,4.10531535914725,2.1265811273519164,0.5965566621544192,-0.04128507261807166,1.042543447000245,0.28220805924936154,-0.17342429277519616,0.5965566621544192,-0.08515151713377264,3.3440660042253465,-0.019418398789169906,0.5551449816119026,-0.603071756954555,3.7862935365121144,-1.221867139462494,-0.7191528925187254,-0.3973599555513764,-0.1956065568925503,3.243881511379576,3.9466779732067017,1.1020654814306523,-0.5111409380756051,-1.0032971173184342,0.13243023164297438,-0.4654794845873636,-0.5111409380756051,-0.2624316007781427,1.2788703326571973,1.2788703326571973,0.4927433790687372,0.5343825284198839
3,381
Outer membrane
26
95
3.300128
0.000966
P57105,Q13505,Q9NS69,Q8WWV3,O60313,Q6NUM9,Q8WXH0,P42704,Q9UKU0,Q8N4H5,P30536,O00429,Q8WY22,Q9Y6C9,P21796,P09601,Q9HCL2,Q5HYI7,O43169,Q9NX63,P45880,Q99720,Q8IWA4,Q9GZY8,P50402,Q8N2A8
Localization
GO Cellular component
msigdb_gocc
131,9,16,143,264,402,289,409,159,37,40,296,55,320,185,69,71,79,81,342,350,97,376,370,244,248
2557,568,296,3369,81,264,2176,3077,1028,1942,2826,1149,1943,3255,2487,69,3119,2095,185,40,2449,3200,1336,409,350,244,1395,542,3106,131,3034,817,543,9,1686,658,2012,982,560,79,3139,1588,402,3140,1735,2814,2020,376,770,1134,2200,574,248,37,1866,1541,691,143,289,55,2072,2691,2943,2027,426,2077,2253,97,1041,1365,1240,2591,370,2722,71,906,907,16,2552,1245,601,1880,3094,342,2119,695,1072,2513,2315,1625,159,1421,1935,2042,320
-0.5570041480733425,0.6994346651191702,1.2006123561295081,-3.5019766940373662,2.41483248829878,1.2788703326571973,-0.3521916978029156,-1.0032971173184342,0.2609348885354999,-0.24010992570608994,-0.7425282805304556,0.1754315665029435,-0.24010992570608994,-1.3703554606513444,-0.5111409380756051,2.6269341644334787,-1.051450154863121,-0.30721638022967535,1.5679201137609433,3.294063684318148,-0.48828515470051204,-1.221867139462494,0.06761072205801114,0.9426694105267227,1.0822579505106387,1.3372321800117861,0.04591856434758408,0.740329474853222,-1.0273443454433155,1.86895187853838,-0.9553767442654298,0.42999594114352935,0.740329474853222,4.10531535914725,-0.10715181947123369,0.5965566621544192,-0.2624316007781427,0.3034406273252866,0.7199001923772445,2.4504202205674956,-1.07561496694313,-0.04128507261807166,0.9627120620801529,-1.07561496694313,-0.12919720072059518,-0.7191528925187254,-0.2624316007781427,1.0226361470657186,0.47186627057669517,0.1968694596042953,-0.3521916978029156,0.6994346651191702,1.3372321800117861,3.3440660042253465,-0.1956065568925503,-0.019418398789169906,0.5551449816119026,1.8130577786414614,1.2398050154301583,3.0242997241481966,-0.28480032142736955,-0.6261830525123374,-0.8365724257127242,-0.2624316007781427,0.9225924964376042,-0.28480032142736955,-0.37475155706455276,2.235426922202329,0.2609348885354999,0.06761072205801114,0.13243023164297438,-0.5570041480733425,1.042543447000245,-0.649346465031488,2.5918188642299147,0.3668969742024014,0.3668969742024014,3.9466779732067017,-0.5340471596998287,0.13243023164297438,0.6583941161256206,-0.1956065568925503,-1.0032971173184342,1.1020654814306523,-0.30721638022967535,0.5551449816119026,0.23962088616631888,-0.5111409380756051,-0.3973599555513764,-0.06319602389665722,1.700516799454386,0.04591856434758408,-0.21783500662433905,-0.2624316007781427,1.1612911271561115
3,381
Intrinsic component of mitochondrial membrane
20
50
3.25563
0.001131
O60830,O95563,P57105,Q9Y4W6,Q13505,Q8N8Q8,Q99595,Q9BPX6,O14925,Q53S58,Q5HYI7,Q9NX63,O75880,Q9Y2R0,Q6P4A7,P17152,Q9NWR8,Q9GZY8,Q8IWA4,Q9UG56
Localization
GO Cellular component
msigdb_gocc
4,504,131,399,9,528,18,157,279,208,79,342,466,99,122,484,250,370,376,515
279,2268,4,1028,466,1942,504,1149,1518,484,3200,1763,1395,131,2713,9,2063,658,1778,982,560,208,79,1588,122,1735,376,1134,2200,528,1209,691,1168,18,157,1238,1240,370,1412,1741,1278,1022,1245,250,342,515,1625,99,399,2042
1.2398050154301583,-0.3973599555513764,4.919035001410219,0.2609348885354999,0.8419387390190867,-0.24010992570608994,0.7810800557959103,0.1754315665029435,-0.019418398789169906,0.8216878926093156,-1.221867139462494,-0.15128793340057795,0.04591856434758408,1.86895187853838,-0.649346465031488,4.10531535914725,-0.28480032142736955,0.5965566621544192,-0.15128793340057795,0.3034406273252866,0.7199001923772445,1.4723284237534975,2.4504202205674956,-0.04128507261807166,1.9430943192648507,-0.12919720072059518,1.0226361470657186,0.1968694596042953,-0.3521916978029156,0.7607227005345416,0.1539519038710691,0.5551449816119026,0.1754315665029435,3.7862935365121144,1.700516799454386,0.13243023164297438,0.13243023164297438,1.042543447000245,0.04591856434758408,-0.12919720072059518,0.11086630745425535,0.28220805924936154,0.13243023164297438,1.3372321800117861,1.1020654814306523,0.7810800557959103,-0.06319602389665722,2.235426922202329,0.9827206223582612,-0.2624316007781427
3,381
Intrinsic component of mitochondrial inner membrane
16
34
3.243264
0.001182
O75880,O14925,Q9Y2R0,O60830,O95563,Q9Y4W6,Q13505,P17152,Q9NWR8,Q8N8Q8,Q53S58,Q5HYI7,Q99595,Q9NX63,Q9UG56,Q6P4A7
Localization
GO Cellular component
msigdb_gocc
466,279,99,4,504,399,9,484,250,528,208,79,18,342,515,122
279,2268,4,1028,466,504,484,3200,1763,2713,9,2063,1778,982,560,208,79,1588,122,1735,528,1209,1168,18,1412,1741,1278,1245,250,342,515,99,399,2042
1.2398050154301583,-0.3973599555513764,4.919035001410219,0.2609348885354999,0.8419387390190867,0.7810800557959103,0.8216878926093156,-1.221867139462494,-0.15128793340057795,-0.649346465031488,4.10531535914725,-0.28480032142736955,-0.15128793340057795,0.3034406273252866,0.7199001923772445,1.4723284237534975,2.4504202205674956,-0.04128507261807166,1.9430943192648507,-0.12919720072059518,0.7607227005345416,0.1539519038710691,0.1754315665029435,3.7862935365121144,0.04591856434758408,-0.12919720072059518,0.11086630745425535,0.13243023164297438,1.3372321800117861,1.1020654814306523,0.7810800557959103,2.235426922202329,0.9827206223582612,-0.2624316007781427
3,381
Golgi cisterna membrane
10
20
3.109449
0.001874
O00461,Q8WVQ1,Q9H4A5,P0CG08,Q10472,Q08379,Q9H4A6,Q15363,Q10713,Q8NBZ7
Localization
GO Cellular component
msigdb_gocc
33,488,133,541,359,300,313,436,523,59
33,541,1298,571,2061,300,744,359,523,436,59,1820,488,2251,1066,133,313,1176,1665,783
3.360693802938071,0.740329474853222,0.08925988661092682,0.6994346651191702,-0.28480032142736955,1.2006123561295081,0.4927433790687372,1.0624173267017085,0.7607227005345416,0.9024811471197746,2.8357123156062505,-0.17342429277519616,0.8216878926093156,-0.37475155706455276,0.23962088616631888,1.86895187853838,1.1809678903438237,0.1754315665029435,-0.08515151713377264,0.47186627057669517
3,381
Establishment of protein localization to membrane
38
102
3.105489
0.0019
P40855,Q9H4A5,O60220,P31751,Q9Y5J7,P46379,Q7L5D6,Q8N8Q8,Q9Y5J9,Q9NPA0,Q9NS69,O43681,Q9BZG1,O60725,Q96A33,Q13439,P50542,O14737,Q9HD26,P43307,Q9H9H4,Q9UHB9,Q13277,Q9H4A6,Q53H12,P98194,Q9Y5Y5,Q01082,Q9UJY4,Q15629,Q9HD20,Q4J6C6,Q4V328,Q9GZY8,P0DP25,P49069,O15027,Q96QK1
Processes and pathways
GO Biological process
msigdb_gobp
259,133,380,7,272,11,660,528,273,662,16,518,146,19,268,394,650,150,549,30,677,697,422,313,560,571,716,444,480,88,89,232,361,370,240,497,495,637
700,2359,2730,150,495,1706,518,970,380,19,2399,2091,1942,2826,1081,911,1189,2405,1516,240,1898,1995,2832,7,2281,2230,259,1258,30,11,2493,497,1853,650,1955,917,1526,3324,2496,2613,1575,3150,3151,571,1302,444,817,2062,1579,422,394,2778,840,2501,1010,2063,88,897,1616,232,361,560,1783,2986,660,799,845,1589,528,1541,3068,268,637,1019,2432,146,370,962,2884,133,313,2755,677,89,549,662,16,1554,3325,1377,697,2391,480,1885,781,2442,2041,2042,272,273,759,716
0.5343825284198839,-0.44272360620966467,-0.6725623413977179,1.756913855622745,0.8014017254185795,-0.12919720072059518,0.7607227005345416,0.3034406273252866,1.0026952612052977,3.640406128534467,-0.4654794845873636,-0.30721638022967535,-0.24010992570608994,-0.7425282805304556,0.2182658209724741,0.34578486103996076,0.1539519038710691,-0.4654794845873636,-0.019418398789169906,1.3566237550487579,-0.21783500662433905,-0.2624316007781427,-0.7425282805304556,4.1682935038480915,-0.3973599555513764,-0.37475155706455276,1.2983556163200487,0.11086630745425535,3.4104592394541533,4.073724975542204,-0.5111409380756051,0.8014017254185795,-0.1956065568925503,0.5965566621544192,-0.24010992570608994,0.34578486103996076,-0.019418398789169906,-1.8303148472046438,-0.5111409380756051,-0.5800122352625738,-0.04128507261807166,-1.0998392081028667,-1.0998392081028667,0.6994346651191702,0.08925988661092682,0.8823351884307354,0.42999594114352935,-0.28480032142736955,-0.04128507261807166,0.9225924964376042,0.9827206223582612,-0.6958310323456385,0.4090022965830154,-0.5111409380756051,0.28220805924936154,-0.28480032142736955,2.3433660052850382,0.3668969742024014,-0.06319602389665722,1.3759843869710013,1.0624173267017085,0.7199001923772445,-0.15128793340057795,-0.8839252917779894,0.5965566621544192,0.45095052821872006,0.4090022965830154,-0.04128507261807166,0.7607227005345416,-0.019418398789169906,-0.979308054094136,1.2788703326571973,0.6172062909671789,0.28220805924936154,-0.4654794845873636,1.7943710577317065,1.042543447000245,0.32463281965659274,-0.7894410947493521,1.86895187853838,1.1809678903438237,-0.6725623413977179,0.5758696256500044,2.3433660052850382,0.740329474853222,0.5965566621544192,3.9466779732067017,-0.019418398789169906,-1.8303148472046438,0.06761072205801114,0.5551449816119026,-0.44272360620966467,0.8419387390190867,-0.1956065568925503,0.47186627057669517,-0.4654794845873636,-0.2624316007781427,-0.2624316007781427,1.2788703326571973,1.2788703326571973,0.4927433790687372,0.5343825284198839
3,381
Tetratricopeptide-like helical domain superfamily [IPR011990]
38
90
3.103522
0.001912
P13674,O75153,Q9H0B6,Q7L5D6,Q9Y5A7,P50542,O00170,Q9UBV2,Q96EK5,Q8IVL6,P42704,Q5VZ89,Q96TC7,Q9UJX3,Q32P28,Q96DB5,Q96EY7,O15294,P61201,O15460,O43242,Q9BXJ9,Q9Y262,Q15006,Q6PGP7,Q7Z4L5,Q6P3X3,Q6DKK2,O00231,Q92791,O95801,A0AVF1,O75718,Q96BR5,Q02790,Q9UJX4,Q9BQ70,Q6P2P2
Sequence
InterPro Superfamily
interpro_homologous_superfamily
631,6,132,660,406,650,517,290,153,288,409,411,426,826,301,302,562,440,455,828,829,479,736,840,351,96,869,225,356,102,862,603,365,500,743,251,387,127
603,517,356,1628,2266,1285,440,828,829,970,2562,6,365,860,2091,1942,3079,862,631,1435,944,2908,1336,409,889,1260,650,2932,1525,455,1644,743,1006,1399,1773,2714,948,2192,1304,2110,2683,840,1266,2811,2012,301,1535,411,225,127,869,1311,351,2198,660,96,288,3184,2352,102,500,302,153,562,426,1693,1040,1694,387,479,2080,132,1700,2550,2661,2031,1043,2257,290,995,1323,826,251,1465,736,1106,2598,406,1508,2894
0.63781871017397,0.7607227005345416,1.0624173267017085,-0.08515151713377264,-0.3973599555513764,0.08925988661092682,0.8823351884307354,0.4090022965830154,0.4090022965830154,0.3034406273252866,-0.5570041480733425,4.371143071972117,1.042543447000245,0.3879693798278019,-0.30721638022967535,-0.24010992570608994,-1.0032971173184342,0.3879693798278019,0.6172062909671789,0.02418316160624745,0.32463281965659274,-0.8129792586013125,0.06761072205801114,0.9426694105267227,0.3668969742024014,0.11086630745425535,0.5965566621544192,-0.8365724257127242,-0.019418398789169906,0.8621544447614617,-0.08515151713377264,0.4927433790687372,0.28220805924936154,0.04591856434758408,-0.15128793340057795,-0.649346465031488,0.32463281965659274,-0.3521916978029156,0.08925988661092682,-0.30721638022967535,-0.6261830525123374,0.4090022965830154,0.11086630745425535,-0.7191528925187254,-0.2624316007781427,1.2006123561295081,-0.019418398789169906,0.9426694105267227,1.3953142204299533,1.9060774234559776,0.3879693798278019,0.08925988661092682,1.0822579505106387,-0.3521916978029156,0.5965566621544192,2.235426922202329,1.2398050154301583,-1.1728728478703139,-0.4200172014503317,2.1629651899814992,0.8014017254185795,1.2006123561295081,1.7381431283572701,0.7199001923772445,0.9225924964376042,-0.10715181947123369,0.2609348885354999,-0.10715181947123369,1.0026952612052977,0.8419387390190867,-0.28480032142736955,1.86895187853838,-0.10715181947123369,-0.5340471596998287,-0.603071756954555,-0.2624316007781427,0.2609348885354999,-0.37475155706455276,1.2398050154301583,0.3034406273252866,0.08925988661092682,0.42999594114352935,1.3372321800117861,0.02418316160624745,0.5135820626533416,0.2182658209724741,-0.5570041480733425,0.9627120620801529,0.002404259502052453,-0.7894410947493521
3,381
Tetrapyrrole binding
6
16
3.088844
0.002009
Q16850,P09601,P30519,O43169,Q6UW02,Q8WUJ1
Functions
GO Molecular function
msigdb_gomf
35,69,12,81,113,21
568,291,81,939,69,2279,12,1087,35,113,21,1789,2074,584,1243,1416
0.6994346651191702,1.220224679805845,2.41483248829878,0.32463281965659274,2.6269341644334787,-0.3973599555513764,4.026211556527206,0.2182658209724741,3.360693802938071,2.053502337953164,3.6241042724046744,-0.15128793340057795,-0.28480032142736955,0.6789327034592646,0.13243023164297438,0.04591856434758408
3,381
Signaling
10
20
3.076384
0.002095
Q5JRA6,Q99627,Q07820,Q7Z4V5,O15173,O14641,Q8WUJ1,P51858,P43490,Q96PC5
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
547,322,543,261,291,243,21,119,442,386
568,243,291,1288,1475,2327,1723,442,119,817,543,1682,547,261,2816,21,1410,386,322,2391
0.6994346651191702,1.3372321800117861,1.220224679805845,0.08925988661092682,0.002404259502052453,-0.4200172014503317,-0.12919720072059518,0.8823351884307354,1.9800034950873004,0.42999594114352935,0.740329474853222,-0.10715181947123369,0.740329474853222,1.2983556163200487,-0.7191528925187254,3.6241042724046744,0.04591856434758408,1.0026952612052977,1.1415819100244504,-0.44272360620966467
3,381
Cardiac muscle contraction
9
22
3.056378
0.00224
Q9UDW1,P22695,P00403,P16615,O14949,P09493,P13073,P67936,P14406
Processes and pathways
KEGG Pathways
msigdb_kegg
41,139,324,241,147,87,335,214,61
1987,147,324,540,911,357,939,87,2322,1632,335,61,2567,1292,241,886,139,2804,915,2372,214,41
-0.2624316007781427,1.775656457586982,1.1218400811435874,0.740329474853222,0.34578486103996076,1.0624173267017085,0.32463281965659274,2.3433660052850382,-0.4200172014503317,-0.08515151713377264,1.1020654814306523,2.818437377950935,-0.5570041480733425,0.08925988661092682,1.3566237550487579,0.3668969742024014,1.8317167420126779,-0.7191528925187254,0.34578486103996076,-0.44272360620966467,1.433882064981485,3.2606290035101324
3,381
Golgi membrane
40
143
3.041983
0.00235
Q9H4A5,Q9Y287,O95197,Q9Y282,Q13439,Q8TBA6,Q13190,Q10713,Q16739,Q9HD26,P24390,O95249,O00461,P0CG08,O43752,O60476,Q9HC07,Q08379,O95721,Q8NDZ4,Q15392,Q9H4A6,Q15363,P33908,O95070,Q96S66,Q8TB61,Q8NCH0,O43731,Q6ZRP7,Q9P2W9,P49755,Q5T9L3,Q10472,Q8IUD2,Q9H9S5,Q7LGA3,O15027,Q92896,O15260
Localization
GO Cellular component
msigdb_gocc
133,536,265,14,394,276,525,523,25,549,31,281,33,541,169,298,171,300,419,177,50,313,436,53,432,329,461,72,76,340,93,470,95,359,487,114,116,495,254,125
1843,33,2266,2173,495,1329,125,1109,997,76,1801,169,298,1988,608,2270,432,265,281,419,1081,1847,1671,1992,541,1517,3135,2930,1607,1634,31,53,722,791,2608,1998,1336,1637,1678,649,470,651,1764,1298,1438,1261,2103,2494,1855,2286,2575,1768,2496,2142,1575,1679,1440,1340,1301,837,1262,571,2061,300,744,359,1646,523,1484,525,394,1055,2421,746,2580,1615,436,767,50,1232,2685,25,1306,95,340,116,1864,2018,769,1097,487,1972,1207,3252,1165,72,177,1064,461,276,2750,1820,987,1869,254,820,2251,329,1875,2432,1104,661,1020,3048,1320,1069,730,133,313,1243,2755,114,171,549,2082,1501,2119,2512,93,994,2513,2391,3220,1176,2927,14,536,3030,2759,3221,1935,2265,1328
-0.1956065568925503,3.360693802938071,-0.3973599555513764,-0.3521916978029156,0.8014017254185795,0.06761072205801114,1.9060774234559776,0.1968694596042953,0.28220805924936154,2.4859119724571785,-0.17342429277519616,1.6438632266775426,1.2006123561295081,-0.2624316007781427,0.63781871017397,-0.3973599555513764,0.9024811471197746,1.2788703326571973,1.2398050154301583,0.9225924964376042,0.2182658209724741,-0.1956065568925503,-0.10715181947123369,-0.2624316007781427,0.740329474853222,-0.019418398789169906,-1.07561496694313,-0.8365724257127242,-0.06319602389665722,-0.08515151713377264,3.393890352280565,3.0922365590874046,0.5135820626533416,0.45095052821872006,-0.5800122352625738,-0.2624316007781427,0.06761072205801114,-0.08515151713377264,-0.10715181947123369,0.5965566621544192,0.8419387390190867,0.5965566621544192,-0.15128793340057795,0.08925988661092682,0.02418316160624745,0.11086630745425535,-0.30721638022967535,-0.5111409380756051,-0.1956065568925503,-0.3973599555513764,-0.5570041480733425,-0.15128793340057795,-0.5111409380756051,-0.3296800727932999,-0.04128507261807166,-0.10715181947123369,0.02418316160624745,0.06761072205801114,0.08925988661092682,0.4090022965830154,0.11086630745425535,0.6994346651191702,-0.28480032142736955,1.2006123561295081,0.4927433790687372,1.0624173267017085,-0.08515151713377264,0.7607227005345416,0.002404259502052453,0.7607227005345416,0.9827206223582612,0.23962088616631888,-0.4654794845873636,0.4927433790687372,-0.5570041480733425,-0.06319602389665722,0.9024811471197746,0.47186627057669517,3.176688862327145,0.13243023164297438,-0.6261830525123374,3.4930124961624522,0.08925988661092682,2.271506265376009,1.1020654814306523,2.0351672840940456,-0.1956065568925503,-0.2624316007781427,0.47186627057669517,0.2182658209724741,0.8216878926093156,-0.24010992570608994,0.1539519038710691,-1.3454478213353334,0.1754315665029435,2.5742263799667753,1.6059499638802452,0.23962088616631888,0.8621544447614617,1.2593535158381115,-0.6725623413977179,-0.17342429277519616,0.3034406273252866,-0.1956065568925503,1.317809516077553,0.42999594114352935,-0.37475155706455276,1.1218400811435874,-0.1956065568925503,-0.4654794845873636,0.2182658209724741,0.5965566621544192,0.28220805924936154,-0.9553767442654298,0.08925988661092682,0.23962088616631888,0.5135820626533416,1.86895187853838,1.1809678903438237,0.13243023164297438,-0.6725623413977179,2.053502337953164,1.6438632266775426,0.740329474853222,-0.28480032142736955,0.002404259502052453,-0.30721638022967535,-0.5111409380756051,2.2895084167466937,0.3034406273252866,-0.5111409380756051,-0.44272360620966467,-1.2464572039127382,0.1754315665029435,-0.8129792586013125,3.962619402550461,0.7607227005345416,-0.9315027811368324,-0.6725623413977179,-1.2464572039127382,-0.21783500662433905,-0.37475155706455276,0.08925988661092682
3,381
Inorganic molecular entity transmembrane transporter activity
28
77
3.014829
0.002571
P55011,Q96QD8,Q13423,O43681,P00846,P0CG08,P05023,O75964,Q9UDW1,Q9HC07,Q9Y6M7,Q93050,P06576,P21796,P98194,Q96S66,Q9Y487,P00403,Q4KMQ2,P13073,Q9HD20,P45880,Q6P4Q7,Q9Y5K8,P16615,Q9UBX3,Q9C0H2,Q9NWR8
Functions
GO Molecular function
msigdb_gomf
508,396,10,518,32,541,540,39,41,171,172,46,433,185,571,329,74,324,598,335,89,350,362,516,241,121,249,250
1179,1987,518,1631,39,668,324,32,540,911,2734,433,2404,1565,2048,939,541,1632,1518,335,241,1116,886,721,2906,185,591,2670,2804,2417,1571,2098,1295,350,915,3268,1438,2141,508,1125,1574,919,3150,571,2713,1302,2190,10,598,3336,362,1209,1658,1975,46,1592,396,329,1546,249,1982,3124,1928,171,89,3196,250,121,41,877,2927,1421,3012,74,516,2519,172
0.1539519038710691,-0.2624316007781427,0.7607227005345416,-0.08515151713377264,3.294063684318148,0.5758696256500044,1.1218400811435874,3.377301896133515,0.740329474853222,0.34578486103996076,-0.6725623413977179,0.9024811471197746,-0.4654794845873636,-0.04128507261807166,-0.28480032142736955,0.32463281965659274,0.740329474853222,-0.08515151713377264,-0.019418398789169906,1.1020654814306523,1.3566237550487579,0.1968694596042953,0.3668969742024014,0.5135820626533416,-0.8129792586013125,1.5679201137609433,0.6583941161256206,-0.6261830525123374,-0.7191528925187254,-0.4654794845873636,-0.04128507261807166,-0.30721638022967535,0.08925988661092682,1.0822579505106387,0.34578486103996076,-1.4203661597491495,0.02418316160624745,-0.3296800727932999,0.7810800557959103,0.1968694596042953,-0.04128507261807166,0.34578486103996076,-1.0998392081028667,0.6994346651191702,-0.649346465031488,0.08925988661092682,-0.3521916978029156,4.0895286543280465,0.6583941161256206,-1.9888702495275368,1.0624173267017085,0.1539519038710691,-0.08515151713377264,-0.24010992570608994,3.22711382314657,-0.04128507261807166,0.9827206223582612,1.1218400811435874,-0.019418398789169906,1.3372321800117861,-0.24010992570608994,-1.051450154863121,-0.21783500662433905,1.6438632266775426,2.3433660052850382,-1.1973391736481231,1.3372321800117861,1.9615623146195156,3.2606290035101324,0.3879693798278019,-0.8129792586013125,0.04591856434758408,-0.9076857627441651,2.5389712897634884,0.7810800557959103,-0.5111409380756051,1.6438632266775426
3,381
Disproportionate short limb short stature
10
22
3.010832
0.002605
Q7RTS9,Q15125,Q32P28,O00116,Q03164,Q15392,O75718,Q7LGA3,Q8NCM8,Q14739
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
2,293,301,364,17,50,365,116,477,445
364,1382,2701,365,1190,3211,1336,1637,17,745,445,293,50,301,1403,116,2,477,488,3275,2315,1602
1.042543447000245,0.04591856434758408,-0.649346465031488,1.042543447000245,0.1539519038710691,-1.2464572039127382,0.06761072205801114,-0.08515151713377264,3.898748651222953,0.4927433790687372,0.8823351884307354,1.220224679805845,3.176688862327145,1.2006123561295081,0.04591856434758408,2.0351672840940456,5.706293515755285,0.8419387390190867,0.8216878926093156,-1.4454702271609903,-0.3973599555513764,-0.04128507261807166
3,381
Cation transmembrane transporter activity
25
70
2.983083
0.002854
P55011,Q70HW3,Q96QD8,Q13423,O43808,P30825,Q8NEW0,P00846,O43772,P05023,O75964,Q9UDW1,Q9HC07,Q9Y6M7,Q93050,P06576,P98194,Q9Y487,P00403,Q4KMQ2,P13073,Q9HD20,Q6P4Q7,P16615,Q9Y5K8
Functions
GO Molecular function
msigdb_gomf
508,3,396,10,519,274,412,32,280,540,39,41,171,172,46,433,571,74,324,598,335,89,362,241,516
1987,280,519,1631,39,668,324,32,540,911,2734,433,2404,1565,2048,939,1632,1518,335,241,1116,886,721,2906,591,2670,274,2804,1571,2098,1295,915,3268,1438,508,1125,1574,919,3150,571,2713,1302,10,1533,598,362,3,1209,412,1975,46,1592,1168,396,1139,1982,3124,1928,1741,171,89,3196,41,877,2927,3012,74,516,855,172
-0.2624316007781427,1.2398050154301583,0.7607227005345416,-0.08515151713377264,3.294063684318148,0.5758696256500044,1.1218400811435874,3.377301896133515,0.740329474853222,0.34578486103996076,-0.6725623413977179,0.9024811471197746,-0.4654794845873636,-0.04128507261807166,-0.28480032142736955,0.32463281965659274,-0.08515151713377264,-0.019418398789169906,1.1020654814306523,1.3566237550487579,0.1968694596042953,0.3668969742024014,0.5135820626533416,-0.8129792586013125,0.6583941161256206,-0.6261830525123374,1.2593535158381115,-0.7191528925187254,-0.04128507261807166,-0.30721638022967535,0.08925988661092682,0.34578486103996076,-1.4203661597491495,0.02418316160624745,0.7810800557959103,0.1968694596042953,-0.04128507261807166,0.34578486103996076,-1.0998392081028667,0.6994346651191702,-0.649346465031488,0.08925988661092682,4.0895286543280465,-0.019418398789169906,0.6583941161256206,1.0624173267017085,5.649292040265413,0.1539519038710691,0.9426694105267227,-0.24010992570608994,3.22711382314657,-0.04128507261807166,0.1754315665029435,0.9827206223582612,0.1968694596042953,-0.24010992570608994,-1.051450154863121,-0.21783500662433905,-0.12919720072059518,1.6438632266775426,2.3433660052850382,-1.1973391736481231,3.2606290035101324,0.3879693798278019,-0.8129792586013125,-0.9076857627441651,2.5389712897634884,0.7810800557959103,0.4090022965830154,1.6438632266775426
3,381
Disproportionate short stature
12
26
2.965756
0.003019
Q7RTS9,Q15125,Q32P28,O00116,Q03164,Q15392,O75718,Q7LGA3,Q8NCM8,Q14739,Q96HY6,Q9UHX1
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
2,293,301,364,17,50,365,116,477,445,222,63
364,1382,2701,365,1190,3120,3211,1336,1637,17,745,445,1912,293,50,301,1403,116,2,477,488,222,3275,2315,63,1602
1.042543447000245,0.04591856434758408,-0.649346465031488,1.042543447000245,0.1539519038710691,-1.051450154863121,-1.2464572039127382,0.06761072205801114,-0.08515151713377264,3.898748651222953,0.4927433790687372,0.8823351884307354,-0.21783500662433905,1.220224679805845,3.176688862327145,1.2006123561295081,0.04591856434758408,2.0351672840940456,5.706293515755285,0.8419387390190867,0.8216878926093156,1.4146133989581882,-1.4454702271609903,-0.3973599555513764,2.818437377950935,-0.04128507261807166
3,381
protein modifying enzyme
11
29
2.933529
0.003351
Q92791,O60476,Q6P2P2,O60678,O75718,O60725,P33908,Q86X55,Q86YN1,Q6PK18,Q15418
Functions
Panther Protein class
panther_protein_class
102,298,127,238,365,19,53,307,187,186,375
2600,1107,440,828,298,1183,238,19,365,631,53,2101,792,1397,1730,1773,1685,375,2380,127,186,307,187,2427,102,1547,963,2083,2599
-0.5800122352625738,0.1968694596042953,0.8823351884307354,0.4090022965830154,1.2006123561295081,0.1539519038710691,1.3566237550487579,3.640406128534467,1.042543447000245,0.6172062909671789,3.0922365590874046,-0.30721638022967535,0.45095052821872006,0.04591856434758408,-0.12919720072059518,-0.15128793340057795,-0.10715181947123369,1.0226361470657186,-0.44272360620966467,1.9060774234559776,1.5679201137609433,1.1809678903438237,1.5679201137609433,-0.4654794845873636,2.1629651899814992,-0.019418398789169906,0.32463281965659274,-0.28480032142736955,-0.5570041480733425
3,381
primary active transporter
10
25
2.9313
0.003375
O60888,O75381,Q8N4H5,P05023,Q9Y5J7,P12270,Q9NS69,P16615,Q6P4A7,P98194
Functions
Panther Protein class
panther_protein_class
64,161,37,540,272,578,16,241,122,571
64,161,1942,1149,540,911,1516,578,241,1116,2372,571,658,1533,122,37,1590,1168,1498,1462,3124,1741,1878,16,272
2.8011403149891057,1.6816609462841285,-0.24010992570608994,0.1754315665029435,0.740329474853222,0.34578486103996076,-0.019418398789169906,0.6789327034592646,1.3566237550487579,0.1968694596042953,-0.44272360620966467,0.6994346651191702,0.5965566621544192,-0.019418398789169906,1.9430943192648507,3.3440660042253465,-0.04128507261807166,0.1754315665029435,0.002404259502052453,0.02418316160624745,-1.051450154863121,-0.12919720072059518,-0.1956065568925503,3.9466779732067017,1.2788703326571973
3,381
Rhizomelia
6
13
2.913545
0.003574
Q7RTS9,Q15125,O00116,O75718,Q15392,Q03164
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
2,293,364,365,50,17
364,1382,2701,365,1336,1637,17,445,293,50,2,2315,1602
1.042543447000245,0.04591856434758408,-0.649346465031488,1.042543447000245,0.06761072205801114,-0.08515151713377264,3.898748651222953,0.8823351884307354,1.220224679805845,3.176688862327145,5.706293515755285,-0.3973599555513764,-0.04128507261807166
3,381
Protein localization to mitochondrion
27
61
2.88323
0.003936
O60220,O60830,Q9Y5J7,Q9Y5J9,Q8N8Q8,Q15388,Q9NS69,Q99595,P49257,O14737,O00170,Q10713,O14925,P52789,Q8N4H5,P31749,O00429,P30536,P55786,Q8TB36,Q53H12,Q9Y6C9,O43464,O95831,Q9GZY8,P0DP25,Q5JRX3
Processes and pathways
GO Biological process
msigdb_gobp
380,4,272,273,528,658,16,18,649,150,517,523,279,542,37,167,296,40,48,691,560,320,314,219,370,240,368
2557,517,2359,296,150,279,314,785,380,4,2482,1942,683,219,1149,1189,240,3224,1803,2095,2411,1995,40,1334,167,2281,649,1298,542,48,2145,817,523,1911,2063,658,2012,1587,560,368,2018,37,528,691,18,1546,2255,370,1878,16,3094,3325,1503,1883,2442,1935,2042,272,273,759,320
-0.5570041480733425,0.7607227005345416,-0.44272360620966467,1.2006123561295081,1.756913855622745,1.2398050154301583,1.1612911271561115,0.45095052821872006,1.0026952612052977,4.919035001410219,-0.5111409380756051,-0.24010992570608994,0.5551449816119026,1.4146133989581882,0.1754315665029435,0.1539519038710691,1.3566237550487579,-1.2711098312889768,-0.17342429277519616,-0.30721638022967535,-0.4654794845873636,-0.2624316007781427,3.294063684318148,0.06761072205801114,1.6627764647279124,-0.3973599555513764,0.5965566621544192,0.08925988661092682,0.740329474853222,3.2103258670728594,-0.3296800727932999,0.42999594114352935,0.7607227005345416,-0.21783500662433905,-0.28480032142736955,0.5965566621544192,-0.2624316007781427,-0.04128507261807166,0.7199001923772445,1.042543447000245,-0.2624316007781427,3.3440660042253465,0.7607227005345416,0.5551449816119026,3.7862935365121144,-0.019418398789169906,-0.37475155706455276,1.042543447000245,-0.1956065568925503,3.9466779732067017,-1.0032971173184342,-1.8303148472046438,0.002404259502052453,-0.1956065568925503,-0.4654794845873636,-0.21783500662433905,-0.2624316007781427,1.2788703326571973,1.2788703326571973,0.4927433790687372,1.1612911271561115
3,381
Golgi cisterna
13
27
2.872519
0.004072
O95249,O00461,Q8WVQ1,Q9H4A5,P0CG08,Q10472,Q08379,Q9BZG1,Q9H4A6,Q8TBA6,Q15363,Q10713,Q8NBZ7
Localization
GO Cellular component
msigdb_gocc
281,33,488,133,541,359,300,146,313,276,436,523,59
33,281,1671,541,1298,571,2061,300,744,359,523,1615,436,2685,59,276,1820,488,2251,1066,3048,146,133,313,1176,1665,783
3.360693802938071,1.2398050154301583,-0.10715181947123369,0.740329474853222,0.08925988661092682,0.6994346651191702,-0.28480032142736955,1.2006123561295081,0.4927433790687372,1.0624173267017085,0.7607227005345416,-0.06319602389665722,0.9024811471197746,-0.6261830525123374,2.8357123156062505,1.2593535158381115,-0.17342429277519616,0.8216878926093156,-0.37475155706455276,0.23962088616631888,-0.9553767442654298,1.7943710577317065,1.86895187853838,1.1809678903438237,0.1754315665029435,-0.08515151713377264,0.47186627057669517
3,381
Variable expressivity
27
80
2.843673
0.00446
Q8NI60,Q13813,Q70HW3,Q9Y5P6,Q9Y4W6,P03886,O95470,Q15125,O00429,Q9NR77,Q8TD16,Q53H12,O43707,Q9Y3Z3,Q00577,P00403,P00374,Q13868,Q8WVQ1,P07196,P06753,P07602,Q9H9S5,Q9UEY8,Q15058,Q6P4A7,Q9H3H1
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
128,383,3,666,399,15,152,293,296,42,309,560,431,332,580,324,452,85,488,100,357,611,114,643,510,122,389
296,431,1890,1252,1512,2521,152,452,324,739,15,357,100,611,1710,1567,3160,834,1392,1996,1295,1225,2523,3163,946,648,2573,1479,1953,1766,2419,2233,1957,1052,1906,580,1644,2106,2377,1812,3321,1343,3190,383,85,1486,2291,510,293,2344,560,2152,3206,122,2157,3,128,1406,309,488,1273,1457,871,2254,802,389,2386,2885,114,2032,42,1072,2822,643,1507,2442,2443,332,399,666
1.2006123561295081,0.9024811471197746,-0.21783500662433905,0.11086630745425535,-0.019418398789169906,-0.5340471596998287,1.756913855622745,0.8621544447614617,1.1218400811435874,0.4927433790687372,3.9466779732067017,1.0624173267017085,2.181118763924772,0.63781871017397,-0.12919720072059518,-0.04128507261807166,-1.124123309901249,0.4090022965830154,0.04591856434758408,-0.2624316007781427,0.08925988661092682,0.13243023164297438,-0.5340471596998287,-1.124123309901249,0.32463281965659274,0.5965566621544192,-0.5570041480733425,0.002404259502052453,-0.24010992570608994,-0.15128793340057795,-0.4654794845873636,-0.37475155706455276,-0.24010992570608994,0.23962088616631888,-0.21783500662433905,0.6789327034592646,-0.08515151713377264,-0.30721638022967535,-0.44272360620966467,-0.17342429277519616,-1.752059420069416,0.06761072205801114,-1.1973391736481231,1.0026952612052977,2.379148008871439,0.002404259502052453,-0.3973599555513764,0.7810800557959103,1.220224679805845,-0.4200172014503317,0.7199001923772445,-0.3296800727932999,-1.221867139462494,1.9430943192648507,-0.3296800727932999,5.649292040265413,1.9060774234559776,0.04591856434758408,1.1809678903438237,0.8216878926093156,0.11086630745425535,0.02418316160624745,0.3879693798278019,-0.37475155706455276,0.45095052821872006,1.0026952612052977,-0.44272360620966467,-0.7894410947493521,2.053502337953164,-0.2624316007781427,3.243881511379576,0.23962088616631888,-0.7191528925187254,0.6172062909671789,0.002404259502052453,-0.4654794845873636,-0.4654794845873636,1.1218400811435874,0.9827206223582612,0.5965566621544192
3,381
Golgi organization
24
59
2.827778
0.004687
Q7RTS9,Q9H4A5,Q9BVK6,Q8TBA6,Q13190,P49257,P50570,P42858,Q5VU43,Q8NHH9,O43752,Q08379,Q9H4A6,Q15363,Q9H6U6,Q99996,Q8NCM8,Q9P2W9,P49755,Q9UID3,O60763,P06493,O15027,O15260
Processes and pathways
GO Biological process
msigdb_gobp
2,133,661,276,525,649,651,285,286,424,169,300,313,436,449,478,477,93,470,105,608,610,495,125
1107,1469,495,125,1220,169,608,1147,2270,610,941,1256,1998,285,1725,649,470,651,1768,2142,1340,1200,1262,1577,300,1484,525,1963,746,1093,436,286,2,2298,2880,2018,845,477,424,1620,276,987,1869,2251,3219,478,1275,661,133,313,449,2755,93,105,1703,1466,1106,699,1075
0.1968694596042953,0.002404259502052453,0.8014017254185795,1.9060774234559776,0.13243023164297438,1.6438632266775426,0.63781871017397,0.1754315665029435,-0.3973599555513764,0.63781871017397,0.32463281965659274,0.11086630745425535,-0.2624316007781427,1.2398050154301583,-0.12919720072059518,0.5965566621544192,0.8419387390190867,0.5965566621544192,-0.15128793340057795,-0.3296800727932999,0.06761072205801114,0.1539519038710691,0.11086630745425535,-0.04128507261807166,1.2006123561295081,0.002404259502052453,0.7607227005345416,-0.24010992570608994,0.4927433790687372,0.2182658209724741,0.9024811471197746,1.2398050154301583,5.706293515755285,-0.3973599555513764,-0.7894410947493521,-0.2624316007781427,0.4090022965830154,0.8419387390190867,0.9225924964376042,-0.06319602389665722,1.2593535158381115,0.3034406273252866,-0.1956065568925503,-0.37475155706455276,-1.2464572039127382,0.8419387390190867,0.11086630745425535,0.5965566621544192,1.86895187853838,1.1809678903438237,0.8823351884307354,-0.6725623413977179,2.2895084167466937,2.1447860132579213,-0.10715181947123369,0.02418316160624745,0.2182658209724741,0.5551449816119026,0.23962088616631888
3,381
Phosphatase regulator activity
7
23
2.803263
0.005059
Q86XL3,P30154,O43768,P0DP25,P78318,Q01105,Q6IN85
Functions
GO Molecular function
msigdb_gomf
67,299,141,240,112,51,475
1428,141,240,1475,1994,943,299,469,1611,112,51,1529,1531,1402,2346,475,67,3071,1170,1595,1375,2758,2599
0.02418316160624745,1.8130577786414614,1.3566237550487579,0.002404259502052453,-0.2624316007781427,0.32463281965659274,1.2006123561295081,0.8419387390190867,-0.06319602389665722,2.053502337953164,3.1429699146944947,-0.019418398789169906,-0.019418398789169906,0.04591856434758408,-0.4200172014503317,0.8419387390190867,2.7664794786953726,-0.979308054094136,0.1754315665029435,-0.04128507261807166,0.06761072205801114,-0.6725623413977179,-0.5570041480733425
3,381
Alzheimers disease and mirna effects
19
88
2.771562
0.005579
P28072,Q9H0B6,P31751,Q08209,Q9NQC3,O95197,P28074,P20618,P28070,P31749,P33176,P21796,P25054,P49721,P45880,Q99436,P0DP25,P16615,O14641
Processes and pathways
WikiPathways
msigdb_wp
258,132,7,393,144,265,142,266,34,167,420,185,204,221,350,363,240,241,243
810,2995,969,243,811,2520,812,829,265,2797,1082,2734,833,2979,1289,240,1518,1713,1633,241,2904,719,1994,2411,266,185,204,2606,790,2228,2737,941,2229,34,258,142,1256,3260,167,7,420,1335,3055,1336,1952,350,2611,1725,1852,2711,221,704,454,2054,1527,1004,1199,1856,1053,920,1301,1302,1577,1006,2191,393,1399,795,1343,1580,1486,1266,1967,1209,1621,870,363,1545,2589,3292,871,2254,132,144,1043,1505,1025,1421
0.42999594114352935,-0.9076857627441651,0.3034406273252866,1.3372321800117861,0.42999594114352935,-0.5340471596998287,0.42999594114352935,0.4090022965830154,1.2788703326571973,-0.7191528925187254,0.2182658209724741,-0.6725623413977179,0.4090022965830154,-0.8839252917779894,0.08925988661092682,1.3566237550487579,-0.019418398789169906,-0.12919720072059518,-0.08515151713377264,1.3566237550487579,-0.8129792586013125,0.5135820626533416,-0.2624316007781427,-0.4654794845873636,1.2788703326571973,1.5679201137609433,1.4915063959259396,-0.5800122352625738,0.45095052821872006,-0.37475155706455276,-0.6725623413977179,0.32463281965659274,-0.37475155706455276,3.360693802938071,1.2983556163200487,1.8130577786414614,0.11086630745425535,-1.3953280732566287,1.6627764647279124,4.1682935038480915,0.9225924964376042,0.06761072205801114,-0.979308054094136,0.06761072205801114,-0.24010992570608994,1.0822579505106387,-0.5800122352625738,-0.12919720072059518,-0.1956065568925503,-0.649346465031488,1.4146133989581882,0.5343825284198839,0.8621544447614617,-0.28480032142736955,-0.019418398789169906,0.28220805924936154,0.1539519038710691,-0.1956065568925503,0.23962088616631888,0.34578486103996076,0.08925988661092682,0.08925988661092682,-0.04128507261807166,0.28220805924936154,-0.3521916978029156,0.9827206223582612,0.04591856434758408,0.45095052821872006,0.06761072205801114,-0.04128507261807166,0.002404259502052453,0.11086630745425535,-0.24010992570608994,0.1539519038710691,-0.06319602389665722,0.3879693798278019,1.0624173267017085,-0.019418398789169906,-0.5570041480733425,-1.5211834842036118,0.3879693798278019,-0.37475155706455276,1.86895187853838,1.8130577786414614,0.2609348885354999,0.002404259502052453,0.28220805924936154,0.04591856434758408
3,381
Cellular ion homeostasis
27
90
2.771422
0.005581
P55011,P62942,Q9Y4W6,Q96A33,P42858,Q8NEW0,Q9BPX6,Q96TC7,P0CG08,P05023,Q9HC07,P78417,Q9Y6M7,Q93050,Q8IYU8,P06576,P98194,P09601,Q9Y487,Q05086,Q8N511,Q9HD20,O75880,P0DP25,P16615,P09429,Q9NWR8
Processes and pathways
GO Biological process
msigdb_gobp
508,382,399,268,285,412,157,426,541,540,171,44,172,46,176,433,571,69,74,205,83,89,466,240,241,496,250
2359,2173,2268,1184,589,1752,3017,466,3280,860,668,2733,2705,540,911,1082,433,3358,2954,1565,496,69,541,240,1756,1191,1331,241,2736,1715,1116,2096,999,941,3121,2280,1570,1256,2097,1295,285,2101,1955,1298,1438,2418,2372,508,919,1339,382,44,571,1302,205,817,2340,1615,897,982,1162,1268,2539,176,83,1209,412,636,46,268,821,2544,2472,426,2432,157,3111,1983,171,89,3196,250,2391,877,1837,2927,74,399,2519,172
-0.44272360620966467,-0.3521916978029156,-0.3973599555513764,0.1539519038710691,0.6583941161256206,-0.15128793340057795,-0.9315027811368324,0.8419387390190867,-1.470640789074526,0.3879693798278019,0.5758696256500044,-0.6725623413977179,-0.649346465031488,0.740329474853222,0.34578486103996076,0.2182658209724741,0.9024811471197746,-2.595820943289011,-0.8602209755086283,-0.04128507261807166,0.8014017254185795,2.6269341644334787,0.740329474853222,1.3566237550487579,-0.15128793340057795,0.1539519038710691,0.06761072205801114,1.3566237550487579,-0.6725623413977179,-0.12919720072059518,0.1968694596042953,-0.30721638022967535,0.28220805924936154,0.32463281965659274,-1.051450154863121,-0.3973599555513764,-0.04128507261807166,0.11086630745425535,-0.30721638022967535,0.08925988661092682,1.2398050154301583,-0.30721638022967535,-0.24010992570608994,0.08925988661092682,0.02418316160624745,-0.4654794845873636,-0.44272360620966467,0.7810800557959103,0.34578486103996076,0.06761072205801114,1.0026952612052977,3.22711382314657,0.6994346651191702,0.08925988661092682,1.4915063959259396,0.42999594114352935,-0.4200172014503317,-0.06319602389665722,0.3668969742024014,0.3034406273252866,0.1754315665029435,0.11086630745425535,-0.5340471596998287,1.6059499638802452,2.3970023903006923,0.1539519038710691,0.9426694105267227,0.6172062909671789,3.22711382314657,1.2788703326571973,0.42999594114352935,-0.5340471596998287,-0.48828515470051204,0.9225924964376042,-0.4654794845873636,1.700516799454386,-1.0273443454433155,-0.24010992570608994,1.6438632266775426,2.3433660052850382,-1.1973391736481231,1.3372321800117861,-0.44272360620966467,0.3879693798278019,-0.17342429277519616,-0.8129792586013125,2.5389712897634884,0.9827206223582612,-0.5111409380756051,1.6438632266775426
3,381
Cis golgi network
10
17
2.76988
0.005608
O95249,O00461,Q9NPR9,Q08379,P30533,O43731,Q8TBA6,Q99996,P49755,P24390
Localization
GO Cellular component
msigdb_gocc
281,33,228,300,391,76,276,478,470,31
33,76,281,31,391,470,571,300,746,2685,276,1820,987,2251,478,228,699
3.360693802938071,2.4859119724571785,1.2398050154301583,3.393890352280565,0.9827206223582612,0.8419387390190867,0.6994346651191702,1.2006123561295081,0.4927433790687372,-0.6261830525123374,1.2593535158381115,-0.17342429277519616,0.3034406273252866,-0.37475155706455276,0.8419387390190867,1.3953142204299533,0.5551449816119026
3,381
Alzheimers disease
19
87
2.747213
0.00601
P28072,Q9H0B6,P31751,Q08209,Q9NQC3,O95197,P28074,P20618,P28070,P31749,P33176,P21796,P25054,P49721,P45880,Q99436,P0DP25,P16615,O14641
Processes and pathways
WikiPathways
msigdb_wp
258,132,7,393,144,265,142,266,34,167,420,185,204,221,350,363,240,241,243
810,2995,969,243,811,2520,812,829,265,2797,1082,2734,833,2979,1289,240,1518,1713,1633,241,2904,719,1994,2411,266,185,204,2606,790,2228,2737,941,2229,34,258,142,1256,3260,167,7,420,1335,3055,1336,1952,350,2611,1725,1852,2711,221,704,454,2054,1527,1004,1199,1856,1053,920,1301,1302,1577,1006,2191,393,1399,795,1343,1580,1486,1266,1967,1209,1621,363,1545,2589,3292,871,2254,132,144,1043,1505,1025,1421
0.42999594114352935,-0.9076857627441651,0.3034406273252866,1.3372321800117861,0.42999594114352935,-0.5340471596998287,0.42999594114352935,0.4090022965830154,1.2788703326571973,-0.7191528925187254,0.2182658209724741,-0.6725623413977179,0.4090022965830154,-0.8839252917779894,0.08925988661092682,1.3566237550487579,-0.019418398789169906,-0.12919720072059518,-0.08515151713377264,1.3566237550487579,-0.8129792586013125,0.5135820626533416,-0.2624316007781427,-0.4654794845873636,1.2788703326571973,1.5679201137609433,1.4915063959259396,-0.5800122352625738,0.45095052821872006,-0.37475155706455276,-0.6725623413977179,0.32463281965659274,-0.37475155706455276,3.360693802938071,1.2983556163200487,1.8130577786414614,0.11086630745425535,-1.3953280732566287,1.6627764647279124,4.1682935038480915,0.9225924964376042,0.06761072205801114,-0.979308054094136,0.06761072205801114,-0.24010992570608994,1.0822579505106387,-0.5800122352625738,-0.12919720072059518,-0.1956065568925503,-0.649346465031488,1.4146133989581882,0.5343825284198839,0.8621544447614617,-0.28480032142736955,-0.019418398789169906,0.28220805924936154,0.1539519038710691,-0.1956065568925503,0.23962088616631888,0.34578486103996076,0.08925988661092682,0.08925988661092682,-0.04128507261807166,0.28220805924936154,-0.3521916978029156,0.9827206223582612,0.04591856434758408,0.45095052821872006,0.06761072205801114,-0.04128507261807166,0.002404259502052453,0.11086630745425535,-0.24010992570608994,0.1539519038710691,-0.06319602389665722,1.0624173267017085,-0.019418398789169906,-0.5570041480733425,-1.5211834842036118,0.3879693798278019,-0.37475155706455276,1.86895187853838,1.8130577786414614,0.2609348885354999,0.002404259502052453,0.28220805924936154,0.04591856434758408
3,381
Golgi apparatus
61
191
2.725969
0.006411
Q7RTS9,Q5MNZ6,Q9H4A5,O00178,Q9Y287,Q9UNW9,P67812,Q9NX62,Q13439,Q8IXU6,Q8TBA6,P80303,Q13190,Q5VZ89,Q5VU43,Q8N4Q0,Q8NEW0,P24390,P10586,O00461,O43752,O60476,Q9HC07,Q08379,Q93050,Q8TD16,Q969F9,Q9H4A6,Q5VW38,P33908,O95070,Q9NWM8,Q8IYS2,Q9BV57,Q01082,O15212,O95456,P53365,Q9HD45,P09601,Q8NCH0,P25054,Q6ZRP7,Q5BKZ1,Q9UJY4,Q99996,P49755,Q9NPR9,Q8WVQ1,O00231,Q6P179,Q9UID3,O95302,P55327,Q9H9S5,O15027,A6NJ78,Q92896,Q9UG56,Q8NEY8,O15260
Localization
Protein Atlas Subcellular
protein_atlas_subcellular_location_all
2,130,133,379,536,535,135,137,394,145,276,20,525,411,286,29,412,31,282,33,169,298,171,300,46,309,49,313,52,53,432,56,188,448,444,191,441,443,196,69,72,204,340,473,480,478,470,228,488,356,103,105,106,498,114,495,493,254,515,123,125
626,3278,493,379,2359,356,33,2266,604,1469,495,1219,191,1329,125,1668,3076,169,607,298,2176,1988,1251,608,2666,1147,2701,1754,1188,432,106,441,2828,1671,1082,3101,2954,69,282,2980,3135,3120,2410,1607,1634,31,204,2368,2568,2856,53,2282,722,2570,1998,2493,1900,1637,470,650,651,1049,2101,2185,1572,443,2103,2494,1855,498,135,20,837,1262,571,444,1645,2578,2061,300,744,1646,525,394,1861,2837,1683,1231,746,950,2685,473,3242,130,2534,286,2154,52,411,1538,2583,1038,1096,103,1310,340,3294,2,2297,769,2067,3323,1097,845,2426,145,1490,188,1207,1269,29,3252,1165,1691,72,412,123,276,309,2468,1658,488,1016,987,254,1975,46,49,1455,1739,3069,1923,1496,2251,2166,1362,1066,822,1875,478,3155,638,1594,1876,448,2030,1069,3299,1276,730,3027,133,313,3194,2387,2755,114,2629,2886,171,549,196,228,2696,1464,1501,56,137,2513,1281,515,1625,105,480,1885,3312,535,536,2759,3248,1328
0.6172062909671789,-1.470640789074526,0.8014017254185795,1.0026952612052977,-0.44272360620966467,1.0624173267017085,3.360693802938071,-0.3973599555513764,0.63781871017397,0.002404259502052453,0.8014017254185795,0.13243023164297438,1.5297726164341399,0.06761072205801114,1.9060774234559776,-0.10715181947123369,-1.0032971173184342,1.6438632266775426,0.63781871017397,1.2006123561295081,-0.3521916978029156,-0.2624316007781427,0.11086630745425535,0.63781871017397,-0.6261830525123374,0.1754315665029435,-0.649346465031488,-0.15128793340057795,0.1539519038710691,0.9024811471197746,2.1265811273519164,0.8823351884307354,-0.7425282805304556,-0.10715181947123369,0.2182658209724741,-1.0273443454433155,-0.8602209755086283,2.6269341644334787,1.2398050154301583,-0.8839252917779894,-1.07561496694313,-1.051450154863121,-0.4654794845873636,-0.06319602389665722,-0.08515151713377264,3.393890352280565,1.4915063959259396,-0.44272360620966467,-0.5570041480733425,-0.765957559026696,3.0922365590874046,-0.3973599555513764,0.5135820626533416,-0.5570041480733425,-0.2624316007781427,-0.5111409380756051,-0.21783500662433905,-0.08515151713377264,0.8419387390190867,0.5965566621544192,0.5965566621544192,0.23962088616631888,-0.30721638022967535,-0.3521916978029156,-0.04128507261807166,0.8823351884307354,-0.30721638022967535,-0.5111409380756051,-0.1956065568925503,0.8014017254185795,1.8503480686626494,3.6241042724046744,0.4090022965830154,0.11086630745425535,0.6994346651191702,0.8823351884307354,-0.08515151713377264,-0.5570041480733425,-0.28480032142736955,1.2006123561295081,0.4927433790687372,-0.08515151713377264,0.7607227005345416,0.9827206223582612,-0.1956065568925503,-0.7425282805304556,-0.10715181947123369,0.13243023164297438,0.4927433790687372,0.32463281965659274,-0.6261830525123374,0.8419387390190867,-1.3206046610312334,1.8875282907253164,-0.5340471596998287,1.2398050154301583,-0.3296800727932999,3.109168434773678,0.9426694105267227,-0.019418398789169906,-0.5570041480733425,0.2609348885354999,0.2182658209724741,2.1447860132579213,0.08925988661092682,1.1020654814306523,-1.5465566784191769,5.706293515755285,-0.3973599555513764,0.47186627057669517,-0.28480032142736955,-1.8041554667666404,0.2182658209724741,0.4090022965830154,-0.4654794845873636,1.7943710577317065,0.002404259502052453,1.5679201137609433,0.1539519038710691,0.11086630745425535,3.4270086253384453,-1.3454478213353334,0.1754315665029435,-0.10715181947123369,2.5742263799667753,0.9426694105267227,1.9430943192648507,1.2593535158381115,1.1809678903438237,-0.48828515470051204,-0.08515151713377264,0.8216878926093156,0.28220805924936154,0.3034406273252866,1.317809516077553,-0.24010992570608994,3.22711382314657,3.193517570996255,0.02418316160624745,-0.12919720072059518,-0.979308054094136,-0.21783500662433905,0.002404259502052453,-0.37475155706455276,-0.3296800727932999,0.06761072205801114,0.23962088616631888,0.42999594114352935,-0.1956065568925503,0.8419387390190867,-1.0998392081028667,0.6172062909671789,-0.04128507261807166,-0.1956065568925503,0.8823351884307354,-0.2624316007781427,0.23962088616631888,-1.5719984893884524,0.11086630745425535,0.5135820626533416,-0.9315027811368324,1.86895187853838,1.1809678903438237,-1.1973391736481231,-0.44272360620966467,-0.6725623413977179,2.053502337953164,-0.5800122352625738,-0.7894410947493521,1.6438632266775426,0.740329474853222,1.5297726164341399,1.3953142204299533,-0.6261830525123374,0.02418316160624745,0.002404259502052453,3.0072628005053503,1.8503480686626494,-0.5111409380756051,0.11086630745425535,0.7810800557959103,-0.06319602389665722,2.1447860132579213,0.8419387390190867,-0.1956065568925503,-1.674462974706239,0.7607227005345416,0.7607227005345416,-0.6725623413977179,-1.3206046610312334,0.08925988661092682
3,381
Golgi apparatus subcompartment
26
96
2.721554
0.006498
Q9H4A5,Q9NX62,Q13439,Q96ED9,Q9BZG1,Q8TBA6,Q10713,O95249,O00461,P0CG08,O43752,Q9HC07,Q08379,Q9H4A6,Q15363,Q8NBZ7,P53365,Q9BWS9,Q9UJY4,Q99996,Q5T9L3,Q9NPR9,Q8WVQ1,Q10472,Q4J6C6,Q9UID3
Localization
GO Cellular component
msigdb_gocc
133,137,394,403,146,276,523,281,33,541,169,171,300,313,436,59,443,330,480,478,95,228,488,359,232,105
2043,33,760,680,1219,1801,169,2851,1988,1183,608,1147,2792,281,2402,1671,1082,863,541,3135,1607,2873,1634,3225,1998,2493,651,1764,2370,1298,1808,443,2103,2286,2496,1575,1679,2005,1262,571,1644,2059,2061,300,744,359,1646,523,394,746,1615,436,2685,232,95,2534,1132,1864,845,2748,1590,59,276,1820,488,2881,987,1869,403,2251,1066,3219,478,1275,330,3048,1320,146,1368,133,313,171,228,2696,137,2119,966,105,480,1176,2262,1466,3030,1665,1425,783
-0.28480032142736955,3.360693802938071,0.47186627057669517,0.5551449816119026,0.13243023164297438,-0.17342429277519616,1.6438632266775426,-0.765957559026696,-0.2624316007781427,0.1539519038710691,0.63781871017397,0.1754315665029435,-0.7191528925187254,1.2398050154301583,-0.4654794845873636,-0.10715181947123369,0.2182658209724741,0.3879693798278019,0.740329474853222,-1.07561496694313,-0.06319602389665722,-0.7894410947493521,-0.08515151713377264,-1.2711098312889768,-0.2624316007781427,-0.5111409380756051,0.5965566621544192,-0.15128793340057795,-0.44272360620966467,0.08925988661092682,-0.17342429277519616,0.8823351884307354,-0.30721638022967535,-0.3973599555513764,-0.5111409380756051,-0.04128507261807166,-0.10715181947123369,-0.2624316007781427,0.11086630745425535,0.6994346651191702,-0.08515151713377264,-0.28480032142736955,-0.28480032142736955,1.2006123561295081,0.4927433790687372,1.0624173267017085,-0.08515151713377264,0.7607227005345416,0.9827206223582612,0.4927433790687372,-0.06319602389665722,0.9024811471197746,-0.6261830525123374,1.3759843869710013,2.271506265376009,-0.5340471596998287,0.1968694596042953,-0.1956065568925503,0.4090022965830154,-0.6725623413977179,-0.04128507261807166,2.8357123156062505,1.2593535158381115,-0.17342429277519616,0.8216878926093156,-0.7894410947493521,0.3034406273252866,-0.1956065568925503,0.9627120620801529,-0.37475155706455276,0.23962088616631888,-1.2464572039127382,0.8419387390190867,0.11086630745425535,1.1218400811435874,-0.9553767442654298,0.08925988661092682,1.7943710577317065,0.06761072205801114,1.86895187853838,1.1809678903438237,1.6438632266775426,1.3953142204299533,-0.6261830525123374,1.8503480686626494,-0.30721638022967535,0.32463281965659274,2.1447860132579213,0.8419387390190867,0.1754315665029435,-0.37475155706455276,0.02418316160624745,-0.9315027811368324,-0.08515151713377264,0.04591856434758408,0.47186627057669517
3,381
Protein targeting to mitochondrion
21
46
2.700593
0.006922
O60220,O60830,Q9Y5J7,Q9Y5J9,Q15388,Q9NS69,Q99595,P49257,O14737,O00170,Q10713,O14925,Q8N4H5,P30536,P55786,Q8TB36,Q53H12,O43464,O95831,Q9GZY8,Q5JRX3
Processes and pathways
GO Biological process
msigdb_gobp
380,4,272,273,658,16,18,649,150,517,523,279,37,40,48,691,560,314,219,370,368
2557,517,150,279,314,785,380,4,2482,1942,683,219,1149,1189,3224,2411,40,2281,649,1298,48,2145,523,1911,658,2012,1587,560,368,2018,37,691,18,1546,2255,370,1878,16,3325,1503,1883,1935,2042,272,273,759
-0.5570041480733425,0.7607227005345416,1.756913855622745,1.2398050154301583,1.1612911271561115,0.45095052821872006,1.0026952612052977,4.919035001410219,-0.5111409380756051,-0.24010992570608994,0.5551449816119026,1.4146133989581882,0.1754315665029435,0.1539519038710691,-1.2711098312889768,-0.4654794845873636,3.294063684318148,-0.3973599555513764,0.5965566621544192,0.08925988661092682,3.2103258670728594,-0.3296800727932999,0.7607227005345416,-0.21783500662433905,0.5965566621544192,-0.2624316007781427,-0.04128507261807166,0.7199001923772445,1.042543447000245,-0.2624316007781427,3.3440660042253465,0.5551449816119026,3.7862935365121144,-0.019418398789169906,-0.37475155706455276,1.042543447000245,-0.1956065568925503,3.9466779732067017,-1.8303148472046438,0.002404259502052453,-0.1956065568925503,-0.21783500662433905,-0.2624316007781427,1.2788703326571973,1.2788703326571973,0.4927433790687372
3,381
Phenotypic variability
32
105
2.677738
0.007412
Q8NI60,Q13813,Q70HW3,Q9Y5P6,Q9UBB4,Q9Y4W6,P03886,O60313,O95470,P00846,Q15125,O00429,O60333,Q9NR77,Q8TD16,Q53H12,O43707,O14979,Q9Y3Z3,Q00577,P00403,P00374,Q13868,Q8WVQ1,P07196,P06753,P07602,Q9H9S5,Q9UEY8,Q15058,Q6P4A7,Q9H3H1
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
128,383,3,666,664,399,15,264,152,32,293,296,297,42,309,560,431,430,332,580,324,452,85,488,100,357,611,114,643,510,122,389
296,3209,430,431,264,297,1890,1252,1512,2521,152,452,324,32,739,15,357,100,611,3281,1710,1567,3160,1084,834,1335,1392,1996,2137,2739,1295,1225,2523,1394,3163,946,648,2573,1479,1260,1953,2524,1572,1766,2419,2233,1957,1052,1906,580,1644,2106,794,2377,1812,3321,1343,3190,383,85,1486,3058,2291,510,293,2344,560,1159,2152,3206,3007,122,2157,2425,3,128,1406,309,488,901,728,1273,1457,871,2254,802,389,2386,2885,114,2032,42,1071,2925,1072,664,2822,643,1504,1507,2442,2443,332,399,666
1.2006123561295081,-1.2464572039127382,0.9024811471197746,0.9024811471197746,1.2788703326571973,1.2006123561295081,-0.21783500662433905,0.11086630745425535,-0.019418398789169906,-0.5340471596998287,1.756913855622745,0.8621544447614617,1.1218400811435874,3.377301896133515,0.4927433790687372,3.9466779732067017,1.0624173267017085,2.181118763924772,0.63781871017397,-1.470640789074526,-0.12919720072059518,-0.04128507261807166,-1.124123309901249,0.2182658209724741,0.4090022965830154,0.06761072205801114,0.04591856434758408,-0.2624316007781427,-0.3296800727932999,-0.6725623413977179,0.08925988661092682,0.13243023164297438,-0.5340471596998287,0.04591856434758408,-1.124123309901249,0.32463281965659274,0.5965566621544192,-0.5570041480733425,0.002404259502052453,0.11086630745425535,-0.24010992570608994,-0.5340471596998287,-0.04128507261807166,-0.15128793340057795,-0.4654794845873636,-0.37475155706455276,-0.24010992570608994,0.23962088616631888,-0.21783500662433905,0.6789327034592646,-0.08515151713377264,-0.30721638022967535,0.45095052821872006,-0.44272360620966467,-0.17342429277519616,-1.752059420069416,0.06761072205801114,-1.1973391736481231,1.0026952612052977,2.379148008871439,0.002404259502052453,-0.979308054094136,-0.3973599555513764,0.7810800557959103,1.220224679805845,-0.4200172014503317,0.7199001923772445,0.1754315665029435,-0.3296800727932999,-1.221867139462494,-0.9076857627441651,1.9430943192648507,-0.3296800727932999,-0.4654794845873636,5.649292040265413,1.9060774234559776,0.04591856434758408,1.1809678903438237,0.8216878926093156,0.3668969742024014,0.5135820626533416,0.11086630745425535,0.02418316160624745,0.3879693798278019,-0.37475155706455276,0.45095052821872006,1.0026952612052977,-0.44272360620966467,-0.7894410947493521,2.053502337953164,-0.2624316007781427,3.243881511379576,0.23962088616631888,-0.8129792586013125,0.23962088616631888,0.5965566621544192,-0.7191528925187254,0.6172062909671789,0.002404259502052453,0.002404259502052453,-0.4654794845873636,-0.4654794845873636,1.1218400811435874,0.9827206223582612,0.5965566621544192
3,381
Transporter activity
53
183
2.675978
0.007451
P55011,Q70HW3,O95563,O60830,Q96QD8,Q13423,Q9Y5J9,P03886,Q9NS69,O43681,O43808,Q99595,Q8IXU6,P30825,Q8NEW0,P00846,O43772,O14925,Q07820,P0CG08,P30536,O75964,Q9UDW1,O15173,Q9HC07,Q9Y6M7,Q93050,P56556,Q99567,P06576,O43676,P21796,Q8WTV0,Q03518,Q9H2D1,Q96S66,Q8TB61,Q9Y487,P00403,O96000,P13073,Q9HD20,P38435,P49755,P45880,Q14849,Q9NWR8,Q6P4Q7,Q9Y5K8,P16615,Q9UBX3,Q9C0H2,Q6P4A7
Functions
GO Molecular function
msigdb_gomf
508,3,504,4,396,10,273,15,16,518,519,18,145,274,412,32,280,279,543,541,40,39,41,291,171,172,46,435,311,433,58,185,190,315,66,329,461,74,324,334,335,89,220,470,350,360,250,362,516,241,121,249,122
1843,1179,2044,2558,1987,3271,279,1468,1706,291,606,58,518,280,519,4,1752,2854,882,1431,1604,1940,971,1631,39,1942,786,2092,668,883,2929,504,334,1149,324,32,15,2402,540,911,2734,433,2404,1565,1151,2048,939,541,1632,1518,1713,335,241,3160,2905,1116,886,721,2906,185,1634,591,2670,1719,3289,40,274,2804,2417,1571,2098,220,1295,1193,350,915,3268,1678,470,3273,1438,2141,2861,890,1639,2773,1051,508,1125,1574,435,919,3150,3362,1858,571,2713,1302,2959,2190,315,1960,817,543,10,2962,2342,1129,360,658,1533,2780,2244,598,3336,2156,3176,122,362,3,1268,1864,145,1590,1541,800,1209,412,461,1658,190,1975,46,1456,1592,1168,396,329,1362,311,18,1546,1139,2433,693,639,1365,2030,2355,2923,249,1982,66,3124,1276,1928,1741,171,89,1022,16,2593,1550,3196,250,3325,121,41,1377,877,1248,2927,1838,1177,1421,3012,74,273,516,855,2519,172,967
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3,381
Receptor
7
26
2.663622
0.00773
O75381,P57105,Q567V2,Q9NR77,P41214,A6NIH7,Q8WTV0
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
161,131,101,42,182,184,190
184,1603,1801,161,2565,3132,1944,3135,182,131,978,2458,2421,101,2380,1162,190,1543,1498,1462,1984,875,42,1282,3113,202
1.5679201137609433,-0.06319602389665722,-0.17342429277519616,1.6816609462841285,-0.5570041480733425,-1.07561496694313,-0.24010992570608994,-1.07561496694313,1.5869496781055785,1.86895187853838,0.3034406273252866,-0.48828515470051204,-0.4654794845873636,2.181118763924772,-0.44272360620966467,0.1754315665029435,1.5488611378657986,-0.019418398789169906,0.002404259502052453,0.02418316160624745,-0.24010992570608994,0.3879693798278019,3.243881511379576,0.11086630745425535,-1.0273443454433155,1.5106544144638607
3,381
Endoplasmic reticulum golgi intermediate compartment membrane
13
27
2.654035
0.007954
Q03518,Q10472,Q9BVK6,Q08379,Q9Y282,Q15363,Q8N511,P49257,Q13190,O95070,P49755,O15260,P24390
Localization
GO Cellular component
msigdb_gocc
315,359,661,300,14,436,83,649,525,432,470,125,31
125,1109,2270,432,31,2280,649,470,1298,3201,2142,315,1960,300,359,1484,525,1963,436,897,83,820,661,1411,1069,14,699
1.9060774234559776,0.1968694596042953,-0.3973599555513764,0.9024811471197746,3.393890352280565,-0.3973599555513764,0.5965566621544192,0.8419387390190867,0.08925988661092682,-1.221867139462494,-0.3296800727932999,1.1612911271561115,-0.24010992570608994,1.2006123561295081,1.0624173267017085,0.002404259502052453,0.7607227005345416,-0.24010992570608994,0.9024811471197746,0.3668969742024014,2.3970023903006923,0.42999594114352935,0.5965566621544192,0.04591856434758408,0.23962088616631888,3.962619402550461,0.5551449816119026
3,381
Intra golgi traffic
7
16
2.627865
0.008592
O95249,O00461,O43752,O60476,O95721,Q8TBA6,P33908
Processes and pathways
Reactome Pathways
msigdb_reactome
281,33,169,298,419,276,53
33,1109,169,298,281,419,53,2493,1525,1262,525,2685,276,2251,1694,2082
3.360693802938071,0.1968694596042953,1.6438632266775426,1.2006123561295081,1.2398050154301583,0.9225924964376042,3.0922365590874046,-0.5111409380756051,-0.019418398789169906,0.11086630745425535,0.7607227005345416,-0.6261830525123374,1.2593535158381115,-0.37475155706455276,-0.10715181947123369,-0.28480032142736955
3,381
Endomembrane system organization
65
182
2.571815
0.010117
O43633,Q7RTS9,Q9H4A5,P31751,Q9BVK6,P46379,Q7L5D6,Q9NQC3,O95197,Q9NPA0,Q96A33,O43681,Q96ED9,Q8TBA6,Q13190,P49257,Q12981,P50542,P50570,Q16739,P42858,Q5VU43,Q9H9H4,Q5JRA6,Q8NHH9,P10909,P31749,O94901,O43752,O00429,O95721,Q08379,Q13277,Q9H4A6,Q15363,Q8N1F7,Q9H6U6,Q01082,Q13501,Q86XL3,Q9UQB8,Q15075,Q4KMQ2,Q99996,Q8NCM8,P16220,Q15629,Q9P2W9,P49755,Q8IXJ6,Q9UID3,O43760,O14964,O60763,P06493,P16615,Q8WUX9,O75844,P35579,P50402,Q9BRG1,P49069,O15027,Q8N3R9,O15260
Processes and pathways
GO Biological process
msigdb_gobp
256,2,133,7,661,11,660,144,265,662,268,518,403,276,525,649,524,650,651,25,285,286,677,547,424,166,167,667,169,296,419,300,422,313,436,308,449,444,457,67,202,597,598,478,477,336,88,93,470,104,105,607,605,608,610,241,499,239,371,244,388,497,495,385,125
968,2123,3075,296,2173,3209,2481,1107,605,1469,495,125,1220,256,518,169,607,970,2045,608,1147,2047,2270,3223,1989,239,1754,667,2445,265,2733,419,739,610,1565,166,336,241,2955,887,1634,941,1256,167,7,371,1998,1193,285,3163,11,2493,1725,497,649,470,244,650,651,1955,1438,2371,916,1126,1768,2142,1770,1575,3150,1340,1200,837,1262,977,444,1577,2578,300,1484,2062,524,3153,525,422,1963,457,2421,706,746,1093,840,2501,1010,597,1686,436,88,25,1131,598,2986,547,3087,1012,286,2583,1059,660,2,2298,1864,2880,2018,67,845,104,308,385,1656,1589,1492,477,1210,424,1620,276,1543,499,987,1869,2503,1358,268,403,3089,2251,1364,3219,478,388,2114,1275,776,661,962,2884,133,313,756,449,2755,677,1070,2212,3112,662,144,2757,3196,2119,965,1554,2512,2390,93,733,105,1703,2698,1986,1934,1838,1466,202,2393,1747,1106,1422,1935,699,1425,1075
0.3034406273252866,-0.3296800727932999,-1.0032971173184342,1.2006123561295081,-0.3521916978029156,-1.2464572039127382,-0.5111409380756051,0.1968694596042953,0.63781871017397,0.002404259502052453,0.8014017254185795,1.9060774234559776,0.13243023164297438,1.2983556163200487,0.7607227005345416,1.6438632266775426,0.63781871017397,0.3034406273252866,-0.28480032142736955,0.63781871017397,0.1754315665029435,-0.28480032142736955,-0.3973599555513764,-1.2711098312889768,-0.2624316007781427,1.3566237550487579,-0.15128793340057795,0.5758696256500044,-0.48828515470051204,1.2788703326571973,-0.6725623413977179,0.9225924964376042,0.4927433790687372,0.63781871017397,-0.04128507261807166,1.6627764647279124,1.1020654814306523,1.3566237550487579,-0.8602209755086283,0.3668969742024014,-0.08515151713377264,0.32463281965659274,0.11086630745425535,1.6627764647279124,4.1682935038480915,1.0226361470657186,-0.2624316007781427,0.1539519038710691,1.2398050154301583,-1.124123309901249,4.073724975542204,-0.5111409380756051,-0.12919720072059518,0.8014017254185795,0.5965566621544192,0.8419387390190867,1.3372321800117861,0.5965566621544192,0.5965566621544192,-0.24010992570608994,0.02418316160624745,-0.44272360620966467,0.34578486103996076,0.1968694596042953,-0.15128793340057795,-0.3296800727932999,-0.15128793340057795,-0.04128507261807166,-1.0998392081028667,0.06761072205801114,0.1539519038710691,0.4090022965830154,0.11086630745425535,0.3034406273252866,0.8823351884307354,-0.04128507261807166,-0.5570041480733425,1.2006123561295081,0.002404259502052453,-0.28480032142736955,0.7607227005345416,-1.0998392081028667,0.7607227005345416,0.9225924964376042,-0.24010992570608994,0.8621544447614617,-0.4654794845873636,0.5343825284198839,0.4927433790687372,0.2182658209724741,0.4090022965830154,-0.5111409380756051,0.28220805924936154,0.6583941161256206,-0.10715181947123369,0.9024811471197746,2.3433660052850382,3.4930124961624522,0.1968694596042953,0.6583941161256206,-0.8839252917779894,0.740329474853222,-1.0032971173184342,0.28220805924936154,1.2398050154301583,-0.5570041480733425,0.23962088616631888,0.5965566621544192,5.706293515755285,-0.3973599555513764,-0.1956065568925503,-0.7894410947493521,-0.2624316007781427,2.7664794786953726,0.4090022965830154,2.1447860132579213,1.1809678903438237,1.0026952612052977,-0.08515151713377264,-0.04128507261807166,0.002404259502052453,0.8419387390190867,0.1539519038710691,0.9225924964376042,-0.06319602389665722,1.2593535158381115,-0.019418398789169906,0.8014017254185795,0.3034406273252866,-0.1956065568925503,-0.5111409380756051,0.06761072205801114,1.2788703326571973,0.9627120620801529,-1.0032971173184342,-0.37475155706455276,0.06761072205801114,-1.2464572039127382,0.8419387390190867,1.0026952612052977,-0.30721638022967535,0.11086630745425535,0.47186627057669517,0.5965566621544192,0.32463281965659274,-0.7894410947493521,1.86895187853838,1.1809678903438237,0.4927433790687372,0.8823351884307354,-0.6725623413977179,0.5758696256500044,0.23962088616631888,-0.3521916978029156,-1.0273443454433155,0.5965566621544192,1.8130577786414614,-0.6725623413977179,-1.1973391736481231,-0.30721638022967535,0.32463281965659274,-0.019418398789169906,-0.5111409380756051,-0.44272360620966467,2.2895084167466937,0.5135820626533416,2.1447860132579213,-0.10715181947123369,-0.6261830525123374,-0.24010992570608994,-0.21783500662433905,-0.17342429277519616,0.02418316160624745,1.5106544144638607,-0.44272360620966467,-0.12919720072059518,0.2182658209724741,0.04591856434758408,-0.21783500662433905,0.5551449816119026,0.04591856434758408,0.23962088616631888
3,381
Calcium ion import
6
13
2.547688
0.010844
Q8IYU8,P16615,O75844,Q9NWR8,P21796,Q9BPX6
Processes and pathways
GO Biological process
msigdb_gobp
176,241,239,250,185,157
856,239,241,1475,185,1335,1302,176,1209,157,3156,250,399
0.3879693798278019,1.3566237550487579,1.3566237550487579,0.002404259502052453,1.5679201137609433,0.06761072205801114,0.08925988661092682,1.6059499638802452,0.1539519038710691,1.700516799454386,-1.0998392081028667,1.3372321800117861,0.9827206223582612
3,381
Bulbar signs
6
12
2.545875
0.0109
P00846,Q99720,P06753,P03886,P35637,O43681
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
32,97,357,15,242,518
518,32,15,2402,357,611,242,946,1453,97,1072,1507
0.7607227005345416,3.377301896133515,3.9466779732067017,-0.4654794845873636,1.0624173267017085,0.63781871017397,1.3566237550487579,0.32463281965659274,0.02418316160624745,2.235426922202329,0.23962088616631888,0.002404259502052453
3,381
Metal ion transport
34
109
2.540997
0.011054
P55011,P62942,Q08209,Q9Y4W6,Q96QD8,P42858,Q8NEW0,Q9BPX6,P05023,P30536,P31749,O15173,O00429,Q9HC07,P78417,Q9Y6M7,P33176,Q8IYU8,O43707,Q14BN4,P21796,P98194,O43865,Q13555,P61201,Q99996,Q9UMX0,Q9HD20,P35609,Q6P4Q7,P0DP25,P16615,O75844,Q9NWR8
Processes and pathways
GO Biological process
msigdb_gobp
508,382,393,399,396,285,412,157,540,40,167,291,296,171,44,172,420,176,431,558,185,571,203,595,455,478,218,89,349,362,240,241,239,250
296,856,291,431,203,1184,1752,3077,2482,239,860,668,1253,2705,2602,540,911,1944,2404,2954,1565,2048,240,2735,884,1191,241,2736,1475,1715,1116,2873,185,974,1898,3121,1570,40,2097,167,420,1335,349,285,2493,1119,1002,651,1197,2372,508,455,2187,3150,1339,382,44,1858,571,1302,1644,743,1127,794,817,393,2776,2062,978,595,2459,558,1616,2244,598,362,1162,2539,176,1209,412,1975,2544,2472,396,2432,1459,478,157,3156,1982,3111,3124,1597,1741,171,89,2593,3196,250,2391,1837,2927,218,2216,3012,1423,399,172
1.2006123561295081,0.3879693798278019,1.220224679805845,0.9024811471197746,1.4915063959259396,0.1539519038710691,-0.15128793340057795,-1.0032971173184342,-0.5111409380756051,1.3566237550487579,0.3879693798278019,0.5758696256500044,0.11086630745425535,-0.649346465031488,-0.5800122352625738,0.740329474853222,0.34578486103996076,-0.24010992570608994,-0.4654794845873636,-0.8602209755086283,-0.04128507261807166,-0.28480032142736955,1.3566237550487579,-0.6725623413977179,0.3668969742024014,0.1539519038710691,1.3566237550487579,-0.6725623413977179,0.002404259502052453,-0.12919720072059518,0.1968694596042953,-0.7894410947493521,1.5679201137609433,0.3034406273252866,-0.21783500662433905,-1.051450154863121,-0.04128507261807166,3.294063684318148,-0.30721638022967535,1.6627764647279124,0.9225924964376042,0.06761072205801114,1.0822579505106387,1.2398050154301583,-0.5111409380756051,0.1968694596042953,0.28220805924936154,0.5965566621544192,0.1539519038710691,-0.44272360620966467,0.7810800557959103,0.8621544447614617,-0.3521916978029156,-1.0998392081028667,0.06761072205801114,1.0026952612052977,3.22711382314657,-0.1956065568925503,0.6994346651191702,0.08925988661092682,-0.08515151713377264,0.4927433790687372,0.1968694596042953,0.45095052821872006,0.42999594114352935,0.9827206223582612,-0.6958310323456385,-0.28480032142736955,0.3034406273252866,0.6583941161256206,-0.48828515470051204,0.7199001923772445,-0.06319602389665722,-0.37475155706455276,0.6583941161256206,1.0624173267017085,0.1754315665029435,-0.5340471596998287,1.6059499638802452,0.1539519038710691,0.9426694105267227,-0.24010992570608994,-0.5340471596998287,-0.48828515470051204,0.9827206223582612,-0.4654794845873636,0.02418316160624745,0.8419387390190867,1.700516799454386,-1.0998392081028667,-0.24010992570608994,-1.0273443454433155,-1.051450154863121,-0.04128507261807166,-0.12919720072059518,1.6438632266775426,2.3433660052850382,-0.5570041480733425,-1.1973391736481231,1.3372321800117861,-0.44272360620966467,-0.17342429277519616,-0.8129792586013125,1.433882064981485,-0.3521916978029156,-0.9076857627441651,0.04591856434758408,0.9827206223582612,1.6438632266775426
3,381
Calcium-binding protein
7
22
2.53574
0.011221
P0DP25,Q8IYU8,P80303,O43852,Q14257,P43307,Q9BPX6
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
240,176,20,117,54,30,157
117,240,2280,3329,284,30,593,1809,20,1645,54,559,3228,2426,176,708,710,157,1104,638,1876,1423
2.016805866932396,1.3566237550487579,-0.3973599555513764,-1.909245977734405,1.2398050154301583,3.4104592394541533,0.6583941161256206,-0.17342429277519616,3.6241042724046744,-0.08515151713377264,3.041315484994378,0.7199001923772445,-1.2711098312889768,-0.4654794845873636,1.6059499638802452,0.5343825284198839,0.5343825284198839,1.700516799454386,0.2182658209724741,0.6172062909671789,-0.1956065568925503,0.04591856434758408
3,381
er
27
91
2.487284
0.012872
P48449,Q9NQC3,Q8TBX8,Q96A33,Q969V3,Q13190,Q12981,O95470,Q07065,Q16850,Q8NHH9,Q9NR31,Q15125,P04843,O15173,O96005,Q15392,Q15363,O00264,Q14739,Q9Y5M8,Q9Y487,Q9P2W9,P49755,Q06136,Q8WUX9,Q969Q5
Localization
OpenCell Localization
opencell_localization
507,144,529,268,267,525,524,152,26,35,424,429,293,539,291,174,50,436,568,445,198,74,93,470,107,499,512
568,1180,291,761,1562,1988,3129,2270,577,1186,2733,152,1222,174,2828,1943,539,1330,2405,1516,2129,2568,942,1997,741,507,1259,470,1764,2370,1298,2233,3324,2613,2142,1575,3352,3038,977,107,26,524,525,445,840,2501,293,436,50,1585,951,35,2986,1059,3176,2538,2584,844,1589,1492,1064,424,529,1407,499,1820,3068,512,267,268,3089,729,1875,2114,873,2355,3194,756,2212,662,144,429,1501,1554,2512,93,2927,2265,74,198,783
0.6994346651191702,0.1539519038710691,1.220224679805845,0.47186627057669517,-0.04128507261807166,-0.2624316007781427,-1.07561496694313,-0.3973599555513764,0.6789327034592646,0.1539519038710691,-0.6725623413977179,1.756913855622745,0.13243023164297438,1.6059499638802452,-0.7425282805304556,-0.24010992570608994,0.740329474853222,0.06761072205801114,-0.4654794845873636,-0.019418398789169906,-0.3296800727932999,-0.5570041480733425,0.32463281965659274,-0.2624316007781427,0.4927433790687372,0.7810800557959103,0.11086630745425535,0.8419387390190867,-0.15128793340057795,-0.44272360620966467,0.08925988661092682,-0.37475155706455276,-1.8303148472046438,-0.5800122352625738,-0.3296800727932999,-0.04128507261807166,-2.342379224436572,-0.9553767442654298,0.3034406273252866,2.1265811273519164,3.4765404463007283,0.7607227005345416,0.7607227005345416,0.8823351884307354,0.4090022965830154,-0.5111409380756051,1.220224679805845,0.9024811471197746,3.176688862327145,-0.04128507261807166,0.32463281965659274,3.360693802938071,-0.8839252917779894,0.23962088616631888,-1.148467709123556,-0.5340471596998287,-0.5570041480733425,0.4090022965830154,-0.04128507261807166,0.002404259502052453,0.23962088616631888,0.9225924964376042,0.7607227005345416,0.04591856434758408,0.8014017254185795,-0.17342429277519616,-0.979308054094136,0.7810800557959103,1.2788703326571973,1.2788703326571973,-1.0032971173184342,0.5135820626533416,-0.1956065568925503,-0.30721638022967535,0.3879693798278019,-0.4200172014503317,-1.1973391736481231,0.4927433790687372,-0.3521916978029156,0.5965566621544192,1.8130577786414614,0.9225924964376042,0.002404259502052453,-0.019418398789169906,-0.5111409380756051,2.2895084167466937,-0.8129792586013125,-0.37475155706455276,2.5389712897634884,1.5297726164341399,0.47186627057669517
3,381
Protein transmembrane transport
8
28
2.478104
0.013208
O75381,O14925,O60830,P31751,Q9NS69,Q99595,Q15629,O95831
Processes and pathways
GO Biological process
msigdb_gobp
161,279,4,7,16,18,88,219
279,785,4,348,161,1942,219,1149,3224,7,470,650,3324,2613,3150,543,658,88,1587,1655,799,1019,18,1878,16,1377,1284,716
1.2398050154301583,0.45095052821872006,4.919035001410219,1.0822579505106387,1.6816609462841285,-0.24010992570608994,1.4146133989581882,0.1754315665029435,-1.2711098312889768,4.1682935038480915,0.8419387390190867,0.5965566621544192,-1.8303148472046438,-0.5800122352625738,-1.0998392081028667,0.740329474853222,0.5965566621544192,2.3433660052850382,-0.04128507261807166,-0.08515151713377264,0.45095052821872006,0.28220805924936154,3.7862935365121144,-0.1956065568925503,3.9466779732067017,0.06761072205801114,0.11086630745425535,0.5343825284198839
3,381
Intracellular protein transmembrane transport
7
24
2.476365
0.013273
O75381,O14925,O60830,P31751,Q99595,Q15629,O95831
Processes and pathways
GO Biological process
msigdb_gobp
161,279,4,7,18,88,219
279,785,4,348,161,1942,219,1149,3224,7,650,3324,2613,3150,658,88,1587,1655,799,1019,18,1878,1377,716
1.2398050154301583,0.45095052821872006,4.919035001410219,1.0822579505106387,1.6816609462841285,-0.24010992570608994,1.4146133989581882,0.1754315665029435,-1.2711098312889768,4.1682935038480915,0.5965566621544192,-1.8303148472046438,-0.5800122352625738,-1.0998392081028667,0.5965566621544192,2.3433660052850382,-0.04128507261807166,-0.08515151713377264,0.45095052821872006,0.28220805924936154,3.7862935365121144,-0.1956065568925503,0.06761072205801114,0.5343825284198839
3,381
Abnormal muscle fiber morphology
22
73
2.472317
0.013424
Q8NI60,Q70HW3,Q9Y4W6,P03886,O60313,Q8WXH0,Q9BPX6,P00846,O14979,O43676,Q13501,Q9H2D1,P00403,P61978,O95831,P35609,Q99720,P07196,P06753,P35637,Q9H9S5,P50402
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
128,3,399,15,264,289,157,32,430,58,457,66,324,339,219,349,97,100,357,242,114,244
2044,430,58,1845,264,3129,1708,219,1149,324,32,739,15,3296,1082,357,100,1710,1894,2799,1518,569,2802,762,973,2569,646,349,242,2710,946,648,244,651,1050,2773,2774,2233,339,1730,2106,457,2459,2779,2810,2533,3087,3,2298,486,928,128,2540,289,2027,1873,97,157,990,776,1041,3111,66,3194,114,2118,2551,2949,2442,2823,399,1840,666
-0.28480032142736955,0.9024811471197746,2.938901920174116,-0.1956065568925503,1.2788703326571973,-1.07561496694313,-0.12919720072059518,1.4146133989581882,0.1754315665029435,1.1218400811435874,3.377301896133515,0.4927433790687372,3.9466779732067017,-1.5719984893884524,0.2182658209724741,1.0624173267017085,2.181118763924772,-0.12919720072059518,-0.21783500662433905,-0.7191528925187254,-0.019418398789169906,0.6994346651191702,-0.7191528925187254,0.47186627057669517,0.3034406273252866,-0.5570041480733425,0.5965566621544192,1.0822579505106387,1.3566237550487579,-0.649346465031488,0.32463281965659274,0.5965566621544192,1.3372321800117861,0.5965566621544192,0.23962088616631888,-0.6958310323456385,-0.6958310323456385,-0.37475155706455276,1.1020654814306523,-0.12919720072059518,-0.30721638022967535,0.8621544447614617,-0.48828515470051204,-0.6958310323456385,-0.7191528925187254,-0.5340471596998287,-1.0032971173184342,5.649292040265413,-0.3973599555513764,0.8216878926093156,0.34578486103996076,1.9060774234559776,-0.5340471596998287,1.2398050154301583,-0.2624316007781427,-0.1956065568925503,2.235426922202329,1.700516799454386,0.3034406273252866,0.47186627057669517,0.2609348885354999,-1.0273443454433155,2.7838210432391537,-1.1973391736481231,2.053502337953164,-0.30721638022967535,-0.5340471596998287,-0.8365724257127242,-0.4654794845873636,-0.7191528925187254,0.9827206223582612,-0.17342429277519616,0.5965566621544192
3,381
Chloride transport
6
12
2.46185
0.013822
P55011,Q96S66,P30536,P54105,Q9C0H2,Q9UHG3
Processes and pathways
GO Biological process
msigdb_gobp
508,329,40,373,249,62
1179,1151,40,1438,2141,373,508,598,329,249,62,2519
0.1539519038710691,0.1754315665029435,3.294063684318148,0.02418316160624745,-0.3296800727932999,1.0226361470657186,0.7810800557959103,0.6583941161256206,1.1218400811435874,1.3372321800117861,2.818437377950935,-0.5111409380756051
3,381
Central scotoma
7
11
2.454916
0.014092
P00846,O60220,O00429,P03886,Q8WWV3,O60313,Q9H6K4
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
32,380,296,15,143,264,319
296,380,264,882,32,15,2803,143,802,319,536
1.2006123561295081,1.0026952612052977,1.2788703326571973,0.3668969742024014,3.377301896133515,3.9466779732067017,-0.7191528925187254,1.8130577786414614,0.45095052821872006,1.1612911271561115,0.7607227005345416
3,381
Class i peroxisomal membrane protein import
6
11
2.439841
0.014694
O75381,P40855,Q9NR77,Q8TB36,O43808,P51648
Processes and pathways
Reactome Pathways
msigdb_reactome
161,259,42,691,519,154
519,161,1719,259,154,1526,1013,1541,691,42,716
0.7607227005345416,1.6816609462841285,-0.12919720072059518,1.2983556163200487,1.7193441514024306,-0.019418398789169906,0.28220805924936154,-0.019418398789169906,0.5551449816119026,3.243881511379576,0.5343825284198839
3,381
Positive regulation of establishment of protein localization
29
100
2.433095
0.01497
O95563,Q9H4A5,P31751,Q9Y282,O14737,Q9H3S7,Q9NR31,O75312,O00410,O00429,P55786,Q9H4A6,Q9C0E2,P15311,Q9H6U6,P98194,O43464,P12270,Q66GS9,P78371,P49755,Q5T9L3,P35580,Q9GZY8,P06493,P50402,Q92544,P49368,Q96QK1
Processes and pathways
GO Biological process
msigdb_gobp
504,133,7,14,150,428,429,538,537,296,48,313,312,555,449,571,314,578,200,456,470,95,367,370,610,244,636,120,637
700,810,537,296,2558,150,314,2176,2870,538,1942,1472,2366,504,2826,2566,610,1710,1672,578,2604,555,2736,1714,2411,2873,1634,1898,1995,2097,7,367,2909,1437,120,470,704,244,1903,763,1298,48,1768,1339,3215,1907,3151,2145,456,1729,571,1302,2578,1399,2062,1579,1911,3153,1613,2936,1008,657,1779,2839,95,200,2814,2018,1786,799,1209,636,1869,1101,3276,637,2432,1364,1458,3178,2255,312,370,428,133,313,449,1832,429,1550,1502,1503,2391,1884,14,1935,936,2041,1249,783
0.5343825284198839,0.42999594114352935,0.740329474853222,1.2006123561295081,-0.5570041480733425,1.756913855622745,1.1612911271561115,-0.3521916978029156,-0.7894410947493521,0.740329474853222,-0.24010992570608994,0.002404259502052453,-0.44272360620966467,0.7810800557959103,-0.7425282805304556,-0.5570041480733425,0.63781871017397,-0.12919720072059518,-0.10715181947123369,0.6789327034592646,-0.5800122352625738,0.7199001923772445,-0.6725623413977179,-0.12919720072059518,-0.4654794845873636,-0.7894410947493521,-0.08515151713377264,-0.21783500662433905,-0.2624316007781427,-0.30721638022967535,4.1682935038480915,1.042543447000245,-0.8129792586013125,0.02418316160624745,1.9615623146195156,0.8419387390190867,0.5343825284198839,1.3372321800117861,-0.21783500662433905,0.47186627057669517,0.08925988661092682,3.2103258670728594,-0.15128793340057795,0.06761072205801114,-1.2464572039127382,-0.21783500662433905,-1.0998392081028667,-0.3296800727932999,0.8621544447614617,-0.12919720072059518,0.6994346651191702,0.08925988661092682,-0.5570041480733425,0.04591856434758408,-0.28480032142736955,-0.04128507261807166,-0.21783500662433905,-1.0998392081028667,-0.06319602389665722,-0.8365724257127242,0.28220805924936154,0.5965566621544192,-0.15128793340057795,-0.7425282805304556,2.271506265376009,1.5106544144638607,-0.7191528925187254,-0.2624316007781427,-0.15128793340057795,0.45095052821872006,0.1539519038710691,0.6172062909671789,-0.1956065568925503,0.2182658209724741,-1.4454702271609903,0.6172062909671789,-0.4654794845873636,0.06761072205801114,0.02418316160624745,-1.148467709123556,-0.37475155706455276,1.1809678903438237,1.042543447000245,0.9225924964376042,1.86895187853838,1.1809678903438237,0.8823351884307354,-0.17342429277519616,0.9225924964376042,-0.019418398789169906,0.002404259502052453,0.002404259502052453,-0.44272360620966467,-0.1956065568925503,3.962619402550461,-0.21783500662433905,0.34578486103996076,-0.2624316007781427,0.13243023164297438,0.47186627057669517
3,381
Endopeptidase activity
20
68
2.422641
0.015408
P28072,Q9Y4E8,P67812,Q9Y4W6,Q96RU2,P22695,P28074,P20618,P28070,Q9NZ08,P13798,O43464,P52888,P49721,Q6P179,Q4J6C6,Q99436,Q5JRX3,O75844,Q96K76
Functions
GO Molecular function
msigdb_gomf
258,134,135,399,269,139,142,266,34,43,181,314,86,221,103,232,363,368,239,124
1844,737,314,831,2482,239,1709,2178,2979,2486,181,1633,2904,266,139,2737,34,258,142,1001,2672,2051,647,1478,1226,2711,221,1153,86,3201,2525,1527,135,1301,523,1303,2936,1036,1345,2620,1687,232,368,1536,103,899,1655,3123,425,1621,1738,955,2657,1138,124,269,931,363,3311,1546,2433,3048,624,43,134,575,399,2868
-0.1956065568925503,0.4927433790687372,1.1612911271561115,0.4090022965830154,-0.5111409380756051,1.3566237550487579,-0.12919720072059518,-0.3521916978029156,-0.8839252917779894,-0.5111409380756051,1.5869496781055785,-0.08515151713377264,-0.8129792586013125,1.2788703326571973,1.8317167420126779,-0.6725623413977179,3.360693802938071,1.2983556163200487,1.8130577786414614,0.28220805924936154,-0.6261830525123374,-0.28480032142736955,0.5965566621544192,0.002404259502052453,0.13243023164297438,-0.649346465031488,1.4146133989581882,0.1754315665029435,2.3612692465651026,-1.221867139462494,-0.5340471596998287,-0.019418398789169906,1.8503480686626494,0.08925988661092682,0.7607227005345416,0.08925988661092682,-0.8365724257127242,0.2609348885354999,0.06761072205801114,-0.5800122352625738,-0.10715181947123369,1.3759843869710013,1.042543447000245,-0.019418398789169906,2.1447860132579213,0.3668969742024014,-0.08515151713377264,-1.051450154863121,0.9225924964376042,-0.06319602389665722,-0.12919720072059518,0.32463281965659274,-0.603071756954555,0.1968694596042953,1.9245993941184603,1.2788703326571973,0.34578486103996076,1.0624173267017085,-1.674462974706239,-0.019418398789169906,-0.4654794845873636,-0.9553767442654298,0.63781871017397,3.243881511379576,1.86895187853838,0.6994346651191702,0.9827206223582612,-0.765957559026696
3,381
Ion homeostasis
31
108
2.419266
0.015552
P55011,P62942,Q9Y4W6,P30519,Q96A33,P42858,Q8NEW0,Q9BPX6,Q9Y5X3,Q96TC7,P0CG08,P05023,P30536,Q9HC07,P78417,Q9Y6M7,Q93050,Q8IYU8,P06576,Q14BN4,P09601,Q9Y487,Q05086,Q8N511,Q9HD20,O75880,Q6P4Q7,P0DP25,P16615,P09429,Q9NWR8
Processes and pathways
GO Biological process
msigdb_gobp
508,382,399,12,268,285,412,157,554,426,541,540,40,171,44,172,46,176,433,558,69,74,205,83,89,466,362,240,241,496,250
2359,2173,1429,2268,1184,589,1752,3017,466,3280,860,3118,668,2733,2705,3331,2602,540,911,1082,433,3358,2954,1565,496,69,1895,541,240,1756,1191,1331,241,2736,1715,1116,2096,999,941,3121,2280,1570,1256,12,40,2097,1295,285,2101,1955,1298,1438,2418,2372,508,919,1339,382,3151,44,571,1302,205,817,2062,2193,2459,2340,558,1615,897,982,362,1162,1268,2539,176,83,800,1209,412,636,46,268,821,2544,2472,426,2432,157,3046,3156,3111,1983,1597,171,89,3196,250,2391,877,1837,2927,74,399,554,2519,172
-0.44272360620966467,-0.3521916978029156,0.02418316160624745,-0.3973599555513764,0.1539519038710691,0.6583941161256206,-0.15128793340057795,-0.9315027811368324,0.8419387390190867,-1.470640789074526,0.3879693798278019,-1.051450154863121,0.5758696256500044,-0.6725623413977179,-0.649346465031488,-1.9357095033877805,-0.5800122352625738,0.740329474853222,0.34578486103996076,0.2182658209724741,0.9024811471197746,-2.595820943289011,-0.8602209755086283,-0.04128507261807166,0.8014017254185795,2.6269341644334787,-0.21783500662433905,0.740329474853222,1.3566237550487579,-0.15128793340057795,0.1539519038710691,0.06761072205801114,1.3566237550487579,-0.6725623413977179,-0.12919720072059518,0.1968694596042953,-0.30721638022967535,0.28220805924936154,0.32463281965659274,-1.051450154863121,-0.3973599555513764,-0.04128507261807166,0.11086630745425535,4.026211556527206,3.294063684318148,-0.30721638022967535,0.08925988661092682,1.2398050154301583,-0.30721638022967535,-0.24010992570608994,0.08925988661092682,0.02418316160624745,-0.4654794845873636,-0.44272360620966467,0.7810800557959103,0.34578486103996076,0.06761072205801114,1.0026952612052977,-1.0998392081028667,3.22711382314657,0.6994346651191702,0.08925988661092682,1.4915063959259396,0.42999594114352935,-0.28480032142736955,-0.3521916978029156,-0.48828515470051204,-0.4200172014503317,0.7199001923772445,-0.06319602389665722,0.3668969742024014,0.3034406273252866,1.0624173267017085,0.1754315665029435,0.11086630745425535,-0.5340471596998287,1.6059499638802452,2.3970023903006923,0.45095052821872006,0.1539519038710691,0.9426694105267227,0.6172062909671789,3.22711382314657,1.2788703326571973,0.42999594114352935,-0.5340471596998287,-0.48828515470051204,0.9225924964376042,-0.4654794845873636,1.700516799454386,-0.9553767442654298,-1.0998392081028667,-1.0273443454433155,-0.24010992570608994,-0.04128507261807166,1.6438632266775426,2.3433660052850382,-1.1973391736481231,1.3372321800117861,-0.44272360620966467,0.3879693798278019,-0.17342429277519616,-0.8129792586013125,2.5389712897634884,0.9827206223582612,0.740329474853222,-0.5111409380756051,1.6438632266775426
3,381
Inability to walk
17
88
2.412631
0.015838
P00846,Q99720,Q7RTS9,Q5MNZ6,P07196,O60220,O00429,Q9UID3,Q9NR77,Q9GZY8,P35637,Q9H9S5,O14949,Q96D71,P61978,P42858,Q71SY5
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
32,97,2,130,100,380,296,105,42,370,242,114,147,277,339,285,352
296,147,761,1562,737,380,3017,1433,2445,3307,32,100,2275,1945,1518,2128,2095,1994,1084,1805,1223,943,1333,2569,242,2051,1675,1295,3272,409,285,2742,2494,1956,1767,2002,339,2646,1812,2335,2336,765,1343,3190,2810,1583,2501,1686,130,2157,352,1653,2,2298,2880,3110,1164,1270,750,691,2022,1065,1453,821,3070,2025,709,277,1457,729,1235,2027,1873,1874,3359,3292,97,1979,1041,370,114,42,663,2993,105,1424,666,2397
1.2006123561295081,1.775656457586982,0.47186627057669517,-0.04128507261807166,0.4927433790687372,1.0026952612052977,-0.9315027811368324,0.02418316160624745,-0.48828515470051204,-1.64874114122769,3.377301896133515,2.181118763924772,-0.3973599555513764,-0.24010992570608994,-0.019418398789169906,-0.3296800727932999,-0.30721638022967535,-0.2624316007781427,0.2182658209724741,-0.17342429277519616,0.13243023164297438,0.32463281965659274,0.06761072205801114,-0.5570041480733425,1.3566237550487579,-0.28480032142736955,-0.10715181947123369,0.08925988661092682,-1.4454702271609903,0.9426694105267227,1.2398050154301583,-0.6725623413977179,-0.5111409380756051,-0.24010992570608994,-0.15128793340057795,-0.2624316007781427,1.1020654814306523,-0.603071756954555,-0.17342429277519616,-0.4200172014503317,-0.4200172014503317,0.47186627057669517,0.06761072205801114,-1.1973391736481231,-0.7191528925187254,-0.04128507261807166,-0.5111409380756051,-0.10715181947123369,1.8875282907253164,-0.3296800727932999,1.0822579505106387,-0.08515151713377264,5.706293515755285,-0.3973599555513764,-0.7894410947493521,-1.0273443454433155,0.1754315665029435,0.11086630745425535,0.4927433790687372,0.5551449816119026,-0.2624316007781427,0.23962088616631888,0.02418316160624745,0.42999594114352935,-0.979308054094136,-0.2624316007781427,0.5343825284198839,1.2593535158381115,0.02418316160624745,0.5135820626533416,0.13243023164297438,-0.2624316007781427,-0.1956065568925503,-0.1956065568925503,-2.595820943289011,-1.5211834842036118,2.235426922202329,-0.24010992570608994,0.2609348885354999,1.042543447000245,2.053502337953164,3.243881511379576,0.5965566621544192,-0.8839252917779894,2.1447860132579213,0.04591856434758408,0.5965566621544192,-0.44272360620966467
3,381
Abnormal epiphyseal ossification
11
20
2.407813
0.016048
O75381,Q7RTS9,P40855,Q15125,Q2M1P5,O00116,P50542,Q14739,Q9UG56,P38435,Q96HY6
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
161,2,259,293,659,364,650,445,515,220,222
364,2701,161,1112,1190,220,259,650,1526,445,1912,293,1585,659,2,222,3359,2315,515,716
1.042543447000245,-0.649346465031488,1.6816609462841285,0.1968694596042953,0.1539519038710691,1.4146133989581882,1.2983556163200487,0.5965566621544192,-0.019418398789169906,0.8823351884307354,-0.21783500662433905,1.220224679805845,-0.04128507261807166,0.5965566621544192,5.706293515755285,1.4146133989581882,-2.595820943289011,-0.3973599555513764,0.7810800557959103,0.5343825284198839
3,381
calmodulin-related
6
15
2.405163
0.016165
P0DP25,Q8IYU8,P80303,O43852,Q14257,Q9BPX6
Functions
Panther Protein class
panther_protein_class
240,176,20,117,54,157
117,240,2097,3329,284,1809,20,1645,54,559,176,710,157,638,1876
2.016805866932396,1.3566237550487579,-0.30721638022967535,-1.909245977734405,1.2398050154301583,-0.17342429277519616,3.6241042724046744,-0.08515151713377264,3.041315484994378,0.7199001923772445,1.6059499638802452,0.5343825284198839,1.700516799454386,0.6172062909671789,-0.1956065568925503
3,381
Mitochondrial protein import
12
36
2.398219
0.016475
O14925,O60220,O60830,Q8N4H5,Q9Y5J7,Q13505,Q9Y5J9,Q5JRX3,Q9NS69,Q99595,Q9NX63,P21796
Processes and pathways
Reactome Pathways
msigdb_reactome
279,380,4,37,272,9,273,368,16,18,342,185
279,785,380,4,3279,1028,2482,971,1942,1149,433,939,3224,1518,1713,185,2670,3200,2771,523,9,658,1587,368,37,18,3207,1878,16,342,1248,2442,2042,272,273,759
1.2398050154301583,0.45095052821872006,1.0026952612052977,4.919035001410219,-1.470640789074526,0.2609348885354999,-0.5111409380756051,0.3034406273252866,-0.24010992570608994,0.1754315665029435,0.9024811471197746,0.32463281965659274,-1.2711098312889768,-0.019418398789169906,-0.12919720072059518,1.5679201137609433,-0.6261830525123374,-1.221867139462494,-0.6958310323456385,0.7607227005345416,4.10531535914725,0.5965566621544192,-0.04128507261807166,1.042543447000245,3.3440660042253465,3.7862935365121144,-1.221867139462494,-0.1956065568925503,3.9466779732067017,1.1020654814306523,0.13243023164297438,-0.4654794845873636,-0.2624316007781427,1.2788703326571973,1.2788703326571973,0.4927433790687372
3,381
Mitochondrial transmembrane transport
20
53
2.39231
0.016743
O60830,O95563,Q9Y4W6,Q15388,Q99595,Q9BPX6,P00846,O43772,O14925,O95202,O75964,Q8IYU8,P06576,P21796,Q9H2D1,P24539,O95831,Q9NWR8,Q9BSK2,Q6P4A7
Processes and pathways
GO Biological process
msigdb_gobp
4,504,399,658,18,157,32,280,279,668,39,176,433,185,66,591,219,250,639,122
279,785,280,4,1752,2482,971,1631,39,1942,668,504,219,1149,32,2734,433,3224,1518,1713,185,973,591,2670,1571,3268,1395,2773,1125,1574,2713,658,3060,1587,122,176,1209,2540,1168,18,157,693,639,66,1928,1741,1878,2593,250,1248,1837,399,855
1.2398050154301583,0.45095052821872006,1.2398050154301583,4.919035001410219,-0.15128793340057795,-0.5111409380756051,0.3034406273252866,-0.08515151713377264,3.294063684318148,-0.24010992570608994,0.5758696256500044,0.7810800557959103,1.4146133989581882,0.1754315665029435,3.377301896133515,-0.6725623413977179,0.9024811471197746,-1.2711098312889768,-0.019418398789169906,-0.12919720072059518,1.5679201137609433,0.3034406273252866,0.6583941161256206,-0.6261830525123374,-0.04128507261807166,-1.4203661597491495,0.04591856434758408,-0.6958310323456385,0.1968694596042953,-0.04128507261807166,-0.649346465031488,0.5965566621544192,-0.979308054094136,-0.04128507261807166,1.9430943192648507,1.6059499638802452,0.1539519038710691,-0.5340471596998287,0.1754315665029435,3.7862935365121144,1.700516799454386,0.5551449816119026,0.6172062909671789,2.7838210432391537,-0.21783500662433905,-0.12919720072059518,-0.1956065568925503,-0.5570041480733425,1.3372321800117861,0.13243023164297438,-0.17342429277519616,0.9827206223582612,0.4090022965830154
3,381
Retrograde vesicle mediated transport golgi to endoplasmic reticulum
7
30
2.38112
0.01726
Q9H4A5,O43731,Q9Y282,Q8TD16,P42858,Q9P2W9,P24390
Processes and pathways
GO Biological process
msigdb_gobp
133,76,14,309,285,93,31
3278,2266,1329,76,2270,2129,1607,31,722,285,1637,1678,470,1855,1440,1262,1484,524,1038,309,1820,987,820,2251,133,313,3169,93,994,14
-1.470640789074526,-0.3973599555513764,0.06761072205801114,2.4859119724571785,-0.3973599555513764,-0.3296800727932999,-0.06319602389665722,3.393890352280565,0.5135820626533416,1.2398050154301583,-0.08515151713377264,-0.10715181947123369,0.8419387390190867,-0.1956065568925503,0.02418316160624745,0.11086630745425535,0.002404259502052453,0.7607227005345416,0.2609348885354999,1.1809678903438237,-0.17342429277519616,0.3034406273252866,0.42999594114352935,-0.37475155706455276,1.86895187853838,1.1809678903438237,-1.124123309901249,2.2895084167466937,0.3034406273252866,3.962619402550461
3,381
FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]
6
12
2.374093
0.017592
P62942,Q96AY3,O95302,Q9Y680,Q9NWM8,Q5T1M5
Sequence
InterPro Domain
interpro_domain
382,168,106,149,56,511
517,106,1118,382,2647,743,1304,2110,511,168,56,149
0.7607227005345416,2.1265811273519164,0.1968694596042953,1.0026952612052977,-0.603071756954555,0.4927433790687372,0.08925988661092682,-0.30721638022967535,0.7810800557959103,1.6627764647279124,3.0072628005053503,1.775656457586982
3,381
Coxa vara
6
16
2.363592
0.018099
Q7RTS9,Q96AY3,Q9Y487,O75718,O95831,Q96HY6
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
2,168,74,365,219,222
2701,365,219,999,2326,650,2613,1159,2,488,168,222,1925,993,2395,74
-0.649346465031488,1.042543447000245,1.4146133989581882,0.28220805924936154,-0.4200172014503317,0.5965566621544192,-0.5800122352625738,0.1754315665029435,5.706293515755285,0.8216878926093156,1.6627764647279124,1.4146133989581882,-0.21783500662433905,0.3034406273252866,-0.44272360620966467,2.5389712897634884
3,381
Decreased number of peripheral myelinated nerve fibers
7
16
2.358926
0.018328
P07196,Q9H0B6,O60333,Q9NR77,Q8TB36,P02545,P50570
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
100,132,297,42,691,739,651
761,297,1148,739,100,2095,1758,651,1955,1812,691,1453,2027,132,1597,42
0.47186627057669517,1.2006123561295081,0.1754315665029435,0.4927433790687372,2.181118763924772,-0.30721638022967535,-0.15128793340057795,0.5965566621544192,-0.24010992570608994,-0.17342429277519616,0.5551449816119026,0.02418316160624745,-0.2624316007781427,1.86895187853838,-0.04128507261807166,3.243881511379576
3,381
Aplasia hypoplasia involving bones of the lower limbs
31
98
2.35173
0.018686
P55011,O95155,Q7RTS9,Q9NX62,Q96A33,Q03164,P50542,P42858,Q9UQE7,Q5JRA6,Q9H3S7,Q96AY3,P00813,Q8N0X7,Q9UHX1,Q96PZ0,O75419,Q13555,P25054,Q08J23,Q8NCM8,P13073,Q8IWS0,O95831,Q96HY6,Q7Z4L5,Q8WVQ1,Q9UGU0,O00116,Q7LGA3,Q8N3R9
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
508,257,2,137,268,17,650,285,679,547,428,168,60,574,63,583,576,595,204,594,477,335,620,219,222,96,488,625,364,116,385
364,2995,2043,2318,812,2223,2089,2701,576,1028,1708,2563,257,668,3188,219,1755,1254,60,739,1190,335,2641,721,2873,3211,204,1948,2135,2492,285,650,2742,2774,508,17,2060,794,594,744,2984,2336,1343,3190,595,2290,2579,1583,2008,2344,2650,2502,547,1689,1816,116,2,96,2018,1489,620,574,385,477,488,2657,1138,268,168,222,583,1874,2918,1925,2384,1213,1215,962,3093,428,1744,1931,2925,137,2315,625,63,996,2040,679,3030,1026,1602,3248,1424,2977,1560,855
1.042543447000245,-0.9076857627441651,-0.28480032142736955,-0.4200172014503317,0.42999594114352935,-0.37475155706455276,-0.30721638022967535,-0.649346465031488,0.6789327034592646,0.2609348885354999,-0.12919720072059518,-0.5570041480733425,1.2983556163200487,0.5758696256500044,-1.1973391736481231,1.4146133989581882,-0.15128793340057795,0.11086630745425535,2.818437377950935,0.4927433790687372,0.1539519038710691,1.1020654814306523,-0.603071756954555,0.5135820626533416,-0.7894410947493521,-1.2464572039127382,1.4915063959259396,-0.24010992570608994,-0.3296800727932999,-0.5111409380756051,1.2398050154301583,0.5965566621544192,-0.6725623413977179,-0.6958310323456385,0.7810800557959103,3.898748651222953,-0.28480032142736955,0.45095052821872006,0.6583941161256206,0.4927433790687372,-0.8839252917779894,-0.4200172014503317,0.06761072205801114,-1.1973391736481231,0.6583941161256206,-0.3973599555513764,-0.5570041480733425,-0.04128507261807166,-0.2624316007781427,-0.4200172014503317,-0.603071756954555,-0.5111409380756051,0.740329474853222,-0.10715181947123369,-0.17342429277519616,2.0351672840940456,5.706293515755285,2.235426922202329,-0.2624316007781427,0.002404259502052453,0.63781871017397,0.6994346651191702,1.0026952612052977,0.8419387390190867,0.8216878926093156,-0.603071756954555,0.1968694596042953,1.2788703326571973,1.6627764647279124,1.4146133989581882,0.6789327034592646,-0.1956065568925503,-0.8129792586013125,-0.21783500662433905,-0.44272360620966467,0.1539519038710691,0.1539519038710691,0.32463281965659274,-1.0032971173184342,0.9225924964376042,-0.12919720072059518,-0.21783500662433905,-0.8129792586013125,1.8503480686626494,-0.3973599555513764,0.63781871017397,2.818437377950935,0.3034406273252866,-0.2624316007781427,0.5758696256500044,-0.9315027811368324,0.28220805924936154,-0.04128507261807166,-1.3206046610312334,0.04591856434758408,-0.8602209755086283,-0.019418398789169906,0.4090022965830154
3,381
Peripheral demyelination
9
16
2.335223
0.019532
P00846,P07196,Q9NR77,P03886,P07602,O43681,P50570,P42704,Q01082
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
32,100,42,15,611,518,651,409,444
518,32,15,100,611,2128,2095,887,409,651,444,691,3192,42,1072,2438
0.7607227005345416,3.377301896133515,3.9466779732067017,2.181118763924772,0.63781871017397,-0.3296800727932999,-0.30721638022967535,0.3668969742024014,0.9426694105267227,0.5965566621544192,0.8823351884307354,0.5551449816119026,-1.1973391736481231,3.243881511379576,0.23962088616631888,-0.4654794845873636
3,381
Ciliary basal body
13
26
2.333877
0.019602
P28070,Q9H3S7,P31749,Q8IUD2,Q9BV73,O75419,Q2M1P5,A0AVF1,Q9P2S5,P15311,O43805,Q96C92,P41208
Localization
GO Cellular component
msigdb_gocc
34,428,167,487,271,576,659,603,207,555,84,215,284
603,84,576,1753,555,34,167,284,1725,2496,3302,657,1057,659,1783,487,2881,215,271,1368,428,207,1884,1074,1602,3116
0.63781871017397,2.379148008871439,0.6789327034592646,-0.15128793340057795,0.7199001923772445,3.360693802938071,1.6627764647279124,1.2398050154301583,-0.12919720072059518,-0.5111409380756051,-1.5975094652852055,0.5965566621544192,0.23962088616631888,0.5965566621544192,-0.15128793340057795,0.8216878926093156,-0.7894410947493521,1.433882064981485,1.2788703326571973,0.06761072205801114,0.9225924964376042,1.4915063959259396,-0.1956065568925503,0.23962088616631888,-0.04128507261807166,-1.0273443454433155
3,381
Abnormal peripheral myelination
13
31
2.319102
0.020389
P00846,P07196,Q9H0B6,O60333,Q9NR77,P03886,Q8TB36,O43681,P02545,P07602,P50570,P42704,Q01082
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
32,100,132,297,42,15,691,518,739,611,651,409,444
761,518,1845,297,1148,32,739,15,100,611,2128,2095,887,1758,409,651,1955,444,1812,1647,952,691,1453,3192,2027,132,1597,42,1072,2438,2397
0.47186627057669517,0.7607227005345416,-0.1956065568925503,1.2006123561295081,0.1754315665029435,3.377301896133515,0.4927433790687372,3.9466779732067017,2.181118763924772,0.63781871017397,-0.3296800727932999,-0.30721638022967535,0.3668969742024014,-0.15128793340057795,0.9426694105267227,0.5965566621544192,-0.24010992570608994,0.8823351884307354,-0.17342429277519616,-0.08515151713377264,0.32463281965659274,0.5551449816119026,0.02418316160624745,-1.1973391736481231,-0.2624316007781427,1.86895187853838,-0.04128507261807166,3.243881511379576,0.23962088616631888,-0.4654794845873636,-0.44272360620966467
3,381
Ensheathment of neurons
12
30
2.317331
0.020486
Q96P11,P10909,P31749,Q9Y4W6,P31751,O75312,Q9NR77,Q8IXJ6,Q15058,Q96PU8,Q7L576,Q8N3R9
Processes and pathways
GO Biological process
msigdb_gobp
156,166,167,399,7,538,42,104,510,216,306,385
1382,538,971,3358,166,998,167,7,1335,1336,613,3201,978,1859,1962,1647,510,1686,2013,306,104,385,1621,156,216,42,2594,1797,1747,399
0.04591856434758408,0.740329474853222,0.3034406273252866,-2.595820943289011,1.6627764647279124,0.28220805924936154,1.6627764647279124,4.1682935038480915,0.06761072205801114,0.06761072205801114,0.63781871017397,-1.221867139462494,0.3034406273252866,-0.1956065568925503,-0.24010992570608994,-0.08515151713377264,0.7810800557959103,-0.10715181947123369,-0.2624316007781427,1.1809678903438237,2.1447860132579213,1.0026952612052977,-0.06319602389665722,1.700516799454386,1.433882064981485,3.243881511379576,-0.5570041480733425,-0.15128793340057795,-0.12919720072059518,0.9827206223582612
3,381
Ion transmembrane transport
47
165
2.316763
0.020517
P55011,Q70HW3,O95563,P62942,Q9Y4W6,Q13423,O43808,P30825,P42858,Q8NEW0,Q9HD26,Q9BPX6,P00846,O43772,P0CG08,P05023,O75964,Q9UDW1,Q9HC07,P78417,Q9Y6M7,Q8IYU8,P06576,O43707,Q14BN4,P98194,P21796,Q9UHG3,Q9H2D1,Q8TB61,O43865,P00403,Q4KMQ2,Q99996,P13073,Q9HD20,Q9UMX0,P45880,P35609,Q9NWR8,Q6P4Q7,P0DP25,P16615,O75844,Q9UBX3,Q9C0H2,Q6P4A7
Processes and pathways
GO Biological process
msigdb_gobp
508,3,504,382,399,10,519,274,285,412,549,157,32,280,541,540,39,41,171,44,172,176,433,431,558,571,185,62,66,461,203,324,598,478,335,89,218,350,349,250,362,240,241,239,121,249,122
1179,2044,1987,431,280,519,203,1184,2046,1752,2852,2854,3077,2482,971,239,1186,1631,39,668,504,1253,324,32,540,911,1082,2734,1944,433,2404,2979,2954,1565,1151,2048,939,541,240,1632,884,1518,1713,335,241,2736,1715,1116,886,721,2906,2873,185,591,2670,1898,3121,1570,3260,2097,274,2804,2417,349,1571,2098,1295,1193,285,350,1119,1002,915,3268,651,1438,2141,2773,1051,1197,2372,508,1125,1574,919,3150,1339,382,44,1858,571,2713,1302,2190,1127,794,817,2776,2062,978,10,2459,2342,1129,558,2501,1615,1533,598,122,362,1162,3,2539,176,1590,1209,412,461,1658,1975,1592,2544,1168,2472,3218,2253,2432,478,157,693,754,1365,3156,249,1982,3111,66,3124,1597,1928,1741,171,89,549,2593,3196,250,121,41,2391,62,877,1248,1837,2927,218,1421,3012,1423,2041,399,855,2519,172
0.1539519038710691,-0.28480032142736955,-0.2624316007781427,0.9024811471197746,1.2398050154301583,0.7607227005345416,1.4915063959259396,0.1539519038710691,-0.28480032142736955,-0.15128793340057795,-0.765957559026696,-0.765957559026696,-1.0032971173184342,-0.5111409380756051,0.3034406273252866,1.3566237550487579,0.1539519038710691,-0.08515151713377264,3.294063684318148,0.5758696256500044,0.7810800557959103,0.11086630745425535,1.1218400811435874,3.377301896133515,0.740329474853222,0.34578486103996076,0.2182658209724741,-0.6725623413977179,-0.24010992570608994,0.9024811471197746,-0.4654794845873636,-0.8839252917779894,-0.8602209755086283,-0.04128507261807166,0.1754315665029435,-0.28480032142736955,0.32463281965659274,0.740329474853222,1.3566237550487579,-0.08515151713377264,0.3668969742024014,-0.019418398789169906,-0.12919720072059518,1.1020654814306523,1.3566237550487579,-0.6725623413977179,-0.12919720072059518,0.1968694596042953,0.3668969742024014,0.5135820626533416,-0.8129792586013125,-0.7894410947493521,1.5679201137609433,0.6583941161256206,-0.6261830525123374,-0.21783500662433905,-1.051450154863121,-0.04128507261807166,-1.3953280732566287,-0.30721638022967535,1.2593535158381115,-0.7191528925187254,-0.4654794845873636,1.0822579505106387,-0.04128507261807166,-0.30721638022967535,0.08925988661092682,0.1539519038710691,1.2398050154301583,1.0822579505106387,0.1968694596042953,0.28220805924936154,0.34578486103996076,-1.4203661597491495,0.5965566621544192,0.02418316160624745,-0.3296800727932999,-0.6958310323456385,0.23962088616631888,0.1539519038710691,-0.44272360620966467,0.7810800557959103,0.1968694596042953,-0.04128507261807166,0.34578486103996076,-1.0998392081028667,0.06761072205801114,1.0026952612052977,3.22711382314657,-0.1956065568925503,0.6994346651191702,-0.649346465031488,0.08925988661092682,-0.3521916978029156,0.1968694596042953,0.45095052821872006,0.42999594114352935,-0.6958310323456385,-0.28480032142736955,0.3034406273252866,4.0895286543280465,-0.48828515470051204,-0.4200172014503317,0.1968694596042953,0.7199001923772445,-0.5111409380756051,-0.06319602389665722,-0.019418398789169906,0.6583941161256206,1.9430943192648507,1.0624173267017085,0.1754315665029435,5.649292040265413,-0.5340471596998287,1.6059499638802452,-0.04128507261807166,0.1539519038710691,0.9426694105267227,0.8621544447614617,-0.08515151713377264,-0.24010992570608994,-0.04128507261807166,-0.5340471596998287,0.1754315665029435,-0.48828515470051204,-1.2464572039127382,-0.37475155706455276,-0.4654794845873636,0.8419387390190867,1.700516799454386,0.5551449816119026,0.4927433790687372,0.06761072205801114,-1.0998392081028667,1.3372321800117861,-0.24010992570608994,-1.0273443454433155,2.7838210432391537,-1.051450154863121,-0.04128507261807166,-0.21783500662433905,-0.12919720072059518,1.6438632266775426,2.3433660052850382,0.740329474853222,-0.5570041480733425,-1.1973391736481231,1.3372321800117861,1.9615623146195156,3.2606290035101324,-0.44272360620966467,2.818437377950935,0.3879693798278019,0.13243023164297438,-0.17342429277519616,-0.8129792586013125,1.433882064981485,0.04591856434758408,-0.9076857627441651,0.04591856434758408,-0.2624316007781427,0.9827206223582612,0.4090022965830154,-0.5111409380756051,1.6438632266775426
3,381
Macromolecule transmembrane transporter activity
6
12
2.313037
0.020721
O14925,Q07820,O60830,Q9NS69,Q99595,P49755
Functions
GO Molecular function
msigdb_gomf
279,543,4,16,18,470
279,4,1942,1149,470,890,3150,543,658,18,16,1377
1.2398050154301583,4.919035001410219,-0.24010992570608994,0.1754315665029435,0.8419387390190867,0.3668969742024014,-1.0998392081028667,0.740329474853222,0.5965566621544192,3.7862935365121144,3.9466779732067017,0.06761072205801114
3,381
Mitotic g2 g2 m phases
24
96
2.303302
0.021262
P28072,Q9BV73,P28074,P20618,O94927,Q14997,Q9Y297,P61289,P41208,Q9BSJ2,P28070,P30154,O75935,Q9H6D7,Q06323,Q66GS9,P51665,O95684,Q9UL46,O43805,Q99996,P49721,O00231,Q99436
Processes and pathways
Reactome Pathways
msigdb_reactome
258,271,142,266,151,546,553,410,284,414,34,299,179,57,316,200,454,82,481,84,478,221,356,363
356,2995,969,2520,1428,1603,829,84,1891,2732,179,151,1188,82,1802,610,1289,1189,1672,2367,2736,719,885,266,720,974,2606,790,2228,2737,2229,34,258,142,943,299,3055,284,3163,1952,2611,2711,221,454,2371,2054,1527,2496,918,410,1482,3326,1004,1199,1339,1856,1611,1857,1005,920,316,795,765,1343,545,2337,1486,2148,706,2779,546,1266,657,1057,200,2880,798,929,1871,1924,363,1545,1875,478,414,871,271,2254,57,1884,481,2975,1025,553,2599,1887
1.0624173267017085,-0.9076857627441651,0.3034406273252866,-0.5340471596998287,0.02418316160624745,-0.06319602389665722,0.4090022965830154,2.379148008871439,-0.21783500662433905,-0.6725623413977179,1.5869496781055785,1.756913855622745,0.1539519038710691,2.3970023903006923,-0.17342429277519616,0.63781871017397,0.08925988661092682,0.1539519038710691,-0.10715181947123369,-0.44272360620966467,-0.6725623413977179,0.5135820626533416,0.3668969742024014,1.2788703326571973,0.5135820626533416,0.3034406273252866,-0.5800122352625738,0.45095052821872006,-0.37475155706455276,-0.6725623413977179,-0.37475155706455276,3.360693802938071,1.2983556163200487,1.8130577786414614,0.32463281965659274,1.2006123561295081,-0.979308054094136,1.2398050154301583,-1.124123309901249,-0.24010992570608994,-0.5800122352625738,-0.649346465031488,1.4146133989581882,0.8621544447614617,-0.44272360620966467,-0.28480032142736955,-0.019418398789169906,-0.5111409380756051,0.34578486103996076,0.9426694105267227,0.002404259502052453,-1.8565492999059354,0.28220805924936154,0.1539519038710691,0.06761072205801114,-0.1956065568925503,-0.06319602389665722,-0.1956065568925503,0.28220805924936154,0.34578486103996076,1.1612911271561115,0.45095052821872006,0.47186627057669517,0.06761072205801114,0.740329474853222,-0.4200172014503317,0.002404259502052453,-0.3296800727932999,0.5343825284198839,-0.6958310323456385,0.740329474853222,0.11086630745425535,0.5965566621544192,0.23962088616631888,1.5106544144638607,-0.7894410947493521,0.45095052821872006,0.34578486103996076,-0.1956065568925503,-0.21783500662433905,1.0624173267017085,-0.019418398789169906,-0.1956065568925503,0.8419387390190867,0.9426694105267227,0.3879693798278019,1.2788703326571973,-0.37475155706455276,2.9560242750898142,-0.1956065568925503,0.8419387390190867,-0.8602209755086283,0.28220805924936154,0.740329474853222,-0.5570041480733425,-0.1956065568925503
3,381
Cation transmembrane transport
34
126
2.300189
0.021438
P55011,Q70HW3,P62942,Q9Y4W6,Q13423,P30825,P42858,Q8NEW0,Q9BPX6,P00846,O43772,P05023,O75964,Q9UDW1,Q9HC07,P78417,Q9Y6M7,Q8IYU8,P06576,O43707,Q14BN4,P21796,P98194,P00403,Q4KMQ2,Q99996,P13073,Q9UMX0,Q9HD20,P35609,Q6P4Q7,P0DP25,P16615,Q9NWR8
Processes and pathways
GO Biological process
msigdb_gobp
508,3,382,399,10,274,285,412,157,32,280,540,39,41,171,44,172,176,433,431,558,185,571,324,598,478,335,218,89,349,362,240,241,250
2044,1987,431,280,1184,1752,2854,3077,2482,1631,39,668,1253,324,32,540,911,1082,2734,1944,433,2404,2979,2954,1565,2048,939,240,1632,884,1518,335,241,2736,1715,1116,886,721,2906,2873,185,591,2670,1898,3121,1570,3260,2097,274,2804,349,1571,2098,1295,285,1119,1002,915,3268,651,1438,1197,2372,508,1125,1574,919,3150,1339,382,44,571,2713,1302,1127,794,817,2776,2062,978,10,2459,558,1615,1533,598,362,1162,3,2539,176,1209,412,1975,1592,2544,1168,2472,3218,2253,2432,478,157,754,3156,1982,3111,3124,1597,1928,1741,171,89,2593,3196,250,41,2391,877,1837,2927,218,1423,399,855,172
-0.28480032142736955,-0.2624316007781427,0.9024811471197746,1.2398050154301583,0.1539519038710691,-0.15128793340057795,-0.765957559026696,-1.0032971173184342,-0.5111409380756051,-0.08515151713377264,3.294063684318148,0.5758696256500044,0.11086630745425535,1.1218400811435874,3.377301896133515,0.740329474853222,0.34578486103996076,0.2182658209724741,-0.6725623413977179,-0.24010992570608994,0.9024811471197746,-0.4654794845873636,-0.8839252917779894,-0.8602209755086283,-0.04128507261807166,-0.28480032142736955,0.32463281965659274,1.3566237550487579,-0.08515151713377264,0.3668969742024014,-0.019418398789169906,1.1020654814306523,1.3566237550487579,-0.6725623413977179,-0.12919720072059518,0.1968694596042953,0.3668969742024014,0.5135820626533416,-0.8129792586013125,-0.7894410947493521,1.5679201137609433,0.6583941161256206,-0.6261830525123374,-0.21783500662433905,-1.051450154863121,-0.04128507261807166,-1.3953280732566287,-0.30721638022967535,1.2593535158381115,-0.7191528925187254,1.0822579505106387,-0.04128507261807166,-0.30721638022967535,0.08925988661092682,1.2398050154301583,0.1968694596042953,0.28220805924936154,0.34578486103996076,-1.4203661597491495,0.5965566621544192,0.02418316160624745,0.1539519038710691,-0.44272360620966467,0.7810800557959103,0.1968694596042953,-0.04128507261807166,0.34578486103996076,-1.0998392081028667,0.06761072205801114,1.0026952612052977,3.22711382314657,0.6994346651191702,-0.649346465031488,0.08925988661092682,0.1968694596042953,0.45095052821872006,0.42999594114352935,-0.6958310323456385,-0.28480032142736955,0.3034406273252866,4.0895286543280465,-0.48828515470051204,0.7199001923772445,-0.06319602389665722,-0.019418398789169906,0.6583941161256206,1.0624173267017085,0.1754315665029435,5.649292040265413,-0.5340471596998287,1.6059499638802452,0.1539519038710691,0.9426694105267227,-0.24010992570608994,-0.04128507261807166,-0.5340471596998287,0.1754315665029435,-0.48828515470051204,-1.2464572039127382,-0.37475155706455276,-0.4654794845873636,0.8419387390190867,1.700516799454386,0.4927433790687372,-1.0998392081028667,-0.24010992570608994,-1.0273443454433155,-1.051450154863121,-0.04128507261807166,-0.21783500662433905,-0.12919720072059518,1.6438632266775426,2.3433660052850382,-0.5570041480733425,-1.1973391736481231,1.3372321800117861,3.2606290035101324,-0.44272360620966467,0.3879693798278019,-0.17342429277519616,-0.8129792586013125,1.433882064981485,0.04591856434758408,0.9827206223582612,0.4090022965830154,1.6438632266775426
3,381
Calcium ion binding
26
95
2.278555
0.022694
Q13813,Q9Y4G8,Q08209,Q96A33,P80303,Q9Y680,Q96D71,P12814,P41208,Q9BPX6,Q96AY3,O60476,Q8IYU8,P33908,Q14257,P43304,Q9NWM8,O43707,P61201,P67936,P35609,Q8WVQ1,O95302,P0DP25,P16615,O43852
Functions
GO Molecular function
msigdb_gomf
383,263,393,268,20,149,277,408,284,157,168,298,176,53,54,304,56,431,455,214,349,488,106,240,241,117
968,2267,784,518,431,117,298,3129,2792,971,1892,668,106,3295,2485,2178,2404,2979,1565,240,408,1191,3344,1291,1331,241,2904,2130,1715,1293,999,1294,2280,942,2981,2097,3329,53,349,284,1636,304,1194,2524,498,593,1809,455,214,20,1858,2680,1645,3368,2191,393,1773,3282,383,2149,54,3204,1684,559,1233,2156,799,1134,2200,176,1064,986,488,268,168,277,710,2432,2433,157,1104,638,2114,1876,713,1413,56,934,3229,2391,1248,3114,781,263,149
0.3034406273252866,-0.3973599555513764,0.45095052821872006,0.7607227005345416,0.9024811471197746,2.016805866932396,1.2006123561295081,-1.07561496694313,-0.7191528925187254,0.3034406273252866,-0.21783500662433905,0.5758696256500044,2.1265811273519164,-1.5719984893884524,-0.5111409380756051,-0.3521916978029156,-0.4654794845873636,-0.8839252917779894,-0.04128507261807166,1.3566237550487579,0.9426694105267227,0.1539519038710691,-2.0961457331392235,0.08925988661092682,0.06761072205801114,1.3566237550487579,-0.8129792586013125,-0.3296800727932999,-0.12919720072059518,0.08925988661092682,0.28220805924936154,0.08925988661092682,-0.3973599555513764,0.32463281965659274,-0.8839252917779894,-0.30721638022967535,-1.909245977734405,3.0922365590874046,1.0822579505106387,1.2398050154301583,-0.08515151713377264,1.1809678903438237,0.1539519038710691,-0.5340471596998287,0.8014017254185795,0.6583941161256206,-0.17342429277519616,0.8621544447614617,1.433882064981485,3.6241042724046744,-0.1956065568925503,-0.6261830525123374,-0.08515151713377264,-3.4700273528571666,-0.3521916978029156,0.9827206223582612,-0.15128793340057795,-1.470640789074526,1.0026952612052977,-0.3296800727932999,3.041315484994378,-1.221867139462494,-0.10715181947123369,0.7199001923772445,0.13243023164297438,-0.3296800727932999,0.45095052821872006,0.1968694596042953,-0.3521916978029156,1.6059499638802452,0.23962088616631888,0.3034406273252866,0.8216878926093156,1.2788703326571973,1.6627764647279124,1.2593535158381115,0.5343825284198839,-0.4654794845873636,-0.4654794845873636,1.700516799454386,0.2182658209724741,0.6172062909671789,-0.30721638022967535,-0.1956065568925503,0.5343825284198839,0.04591856434758408,3.0072628005053503,0.34578486103996076,-1.2711098312889768,-0.44272360620966467,0.13243023164297438,-1.0273443454433155,0.47186627057669517,1.2983556163200487,1.775656457586982
3,381
Protein transmembrane transporter activity
6
11
2.277732
0.022743
O14925,Q07820,O60830,Q9NS69,Q99595,P49755
Functions
GO Molecular function
msigdb_gomf
279,543,4,16,18,470
279,4,1942,1149,470,3150,543,658,18,16,1377
1.2398050154301583,4.919035001410219,-0.24010992570608994,0.1754315665029435,0.8419387390190867,-1.0998392081028667,0.740329474853222,0.5965566621544192,3.7862935365121144,3.9466779732067017,0.06761072205801114
3,381
Organelle biogenesis and maintenance
29
100
2.274203
0.022954
Q13505,Q9BV73,O94927,Q10713,P41208,P00846,Q13561,O75964,O75935,P06576,Q86X55,Q9H6D7,A6NIH7,Q15648,Q66GS9,P78371,O95684,Q9NX63,O43805,Q99996,P24539,P16220,Q8NCM8,Q92973,Q7Z4L5,Q96A65,P17152,A0AVF1,P49368
Processes and pathways
Reactome Pathways
msigdb_reactome
9,271,151,523,284,32,545,39,179,433,307,57,184,572,200,456,82,342,84,478,591,336,477,353,96,489,484,603,120
603,184,1628,2360,84,2897,3349,1028,1753,179,1631,39,151,82,2566,32,3331,610,433,1289,1189,336,484,2736,1714,2129,591,2670,943,2608,1571,3200,284,3163,3268,1437,3238,120,1903,763,3105,2371,1154,1125,1574,2496,918,1482,1339,1857,920,456,1442,2334,523,765,9,1343,545,1486,2148,706,2779,669,657,572,1057,1779,982,1588,200,1735,2880,798,96,307,477,751,3361,987,353,489,1871,3177,2842,1873,478,871,271,2254,1020,57,1744,1245,342,1884,1074,1602,1467,2042
0.63781871017397,1.5679201137609433,-0.08515151713377264,-0.44272360620966467,2.379148008871439,-0.8129792586013125,-2.1774595055002277,0.2609348885354999,-0.15128793340057795,1.5869496781055785,-0.08515151713377264,3.294063684318148,1.756913855622745,2.3970023903006923,-0.5570041480733425,3.377301896133515,-1.9357095033877805,0.63781871017397,0.9024811471197746,0.08925988661092682,0.1539519038710691,1.1020654814306523,0.8216878926093156,-0.6725623413977179,-0.12919720072059518,-0.3296800727932999,0.6583941161256206,-0.6261830525123374,0.32463281965659274,-0.5800122352625738,-0.04128507261807166,-1.221867139462494,1.2398050154301583,-1.124123309901249,-1.4203661597491495,0.02418316160624745,-1.3206046610312334,1.9615623146195156,-0.21783500662433905,0.47186627057669517,-1.0273443454433155,-0.44272360620966467,0.1754315665029435,0.1968694596042953,-0.04128507261807166,-0.5111409380756051,0.34578486103996076,0.002404259502052453,0.06761072205801114,-0.1956065568925503,0.34578486103996076,0.8621544447614617,0.02418316160624745,-0.4200172014503317,0.7607227005345416,0.47186627057669517,4.10531535914725,0.06761072205801114,0.740329474853222,0.002404259502052453,-0.3296800727932999,0.5343825284198839,-0.6958310323456385,0.5758696256500044,0.5965566621544192,0.6994346651191702,0.23962088616631888,-0.15128793340057795,0.3034406273252866,-0.04128507261807166,1.5106544144638607,-0.12919720072059518,-0.7894410947493521,0.45095052821872006,2.235426922202329,1.1809678903438237,0.8419387390190867,0.4927433790687372,-2.6820141819181047,0.3034406273252866,1.0822579505106387,0.8216878926093156,-0.1956065568925503,-1.148467709123556,-0.7425282805304556,-0.1956065568925503,0.8419387390190867,0.3879693798278019,1.2788703326571973,-0.37475155706455276,0.28220805924936154,2.9560242750898142,-0.12919720072059518,0.13243023164297438,1.1020654814306523,-0.1956065568925503,0.23962088616631888,-0.04128507261807166,0.02418316160624745,-0.2624316007781427
3,381
Nucleophile aminohydrolases, N-terminal [IPR029055]
6
17
2.267448
0.023363
P28072,P28070,P28074,P20618,Q06203,P49721
Sequence
InterPro Superfamily
interpro_homologous_superfamily
258,34,142,266,275,221
2520,1893,266,2606,790,2228,2737,2229,34,258,142,2711,221,1527,275,2106,363
-0.5340471596998287,-0.21783500662433905,1.2788703326571973,-0.5800122352625738,0.45095052821872006,-0.37475155706455276,-0.6725623413977179,-0.37475155706455276,3.360693802938071,1.2983556163200487,1.8130577786414614,-0.649346465031488,1.4146133989581882,-0.019418398789169906,1.2593535158381115,-0.30721638022967535,1.0624173267017085
3,381
Cytosolic calcium ion transport
9
25
2.266065
0.023447
P62942,P78417,P0DP25,Q8IYU8,P16615,P42858,Q9NWR8,P21796,Q9BPX6
Processes and pathways
GO Biological process
msigdb_gobp
382,44,240,176,241,285,250,185,157
1184,668,2954,240,241,2736,1715,1116,185,3121,1570,2097,285,1339,382,44,817,2539,176,1209,2544,157,3196,250,399
0.1539519038710691,0.5758696256500044,-0.8602209755086283,1.3566237550487579,1.3566237550487579,-0.6725623413977179,-0.12919720072059518,0.1968694596042953,1.5679201137609433,-1.051450154863121,-0.04128507261807166,-0.30721638022967535,1.2398050154301583,0.06761072205801114,1.0026952612052977,3.22711382314657,0.42999594114352935,-0.5340471596998287,1.6059499638802452,0.1539519038710691,-0.5340471596998287,1.700516799454386,-1.1973391736481231,1.3372321800117861,0.9827206223582612
3,381
Mitochondrion organization
79
202
2.263549
0.023602
O60830,O75153,Q13505,Q8N8Q8,P03886,Q9NS69,Q99595,O00170,Q10713,Q69YU5,P52789,Q9NUQ9,Q8N4H5,P30536,P55786,Q53H12,O43676,P14406,Q9Y4P1,Q9NVT9,Q5HYI7,Q5T9A4,Q9BRT2,Q9Y2R0,O43674,Q9BSK2,Q96QK1,Q7L592,Q5MNZ6,Q9NVI7,Q15388,P49257,P50542,O14737,O95202,P31749,P10909,Q96A26,Q8TB36,O95429,P21796,Q96CU9,Q9NVA1,Q8N163,P49841,Q16543,O95831,Q6DKK2,Q9BSH4,Q9Y5L4,P0DP25,Q8N2A8,Q9Y5J7,Q9Y5J9,O60313,P42858,Q86Y39,O14925,O00429,Q9H4A6,Q9Y6C9,O43464,Q9UDX5,Q9NX63,O96000,P49815,P45880,Q9GZY8,Q5JRX3,Q8IWA4,O60220,Q9Y4W6,P56556,P53365,Q13501,O75880,Q7Z406,P17152,Q9UG56
Processes and pathways
GO Biological process
msigdb_gobp
4,6,9,528,15,16,18,517,523,28,542,36,37,40,48,560,58,61,575,601,79,618,623,99,606,639,637,634,130,663,658,649,650,150,668,167,166,173,691,683,185,709,715,708,704,726,219,225,754,759,240,248,272,273,264,285,287,279,296,313,320,314,343,342,334,338,350,370,368,376,380,399,435,443,457,466,486,484,515
1842,2557,517,2359,296,1987,150,279,314,785,606,58,2268,380,264,4,6,2953,2854,882,3077,1028,1604,2482,1940,2732,466,1942,786,668,883,2929,683,219,334,1149,739,2705,15,2402,3331,1802,2734,1189,2487,1895,240,3224,166,1803,1518,61,484,2411,185,2491,3121,3289,2768,3260,1995,40,167,2281,2134,3284,2051,3200,3212,285,350,915,649,338,704,2232,650,1049,1298,2861,542,443,48,435,2575,2145,1442,1302,2334,817,523,1911,1264,3057,457,9,1683,2063,1686,658,2012,726,2685,2780,2244,982,952,1587,560,79,368,130,618,2746,1588,28,225,1735,2879,634,1864,486,2018,287,376,1134,2200,2717,708,1452,248,37,1866,1787,528,1209,691,1406,2540,2503,173,709,1740,2691,637,2027,931,3218,2077,18,2253,3292,1546,990,623,754,639,2473,1238,1041,1240,2255,3283,370,802,1412,313,2312,1878,906,16,36,715,1245,663,601,1880,2256,3094,342,2438,3325,1503,343,515,1625,1883,1837,1177,2442,99,935,1935,936,575,399,2042,272,273,759,320,967
-0.1956065568925503,-0.5570041480733425,0.7607227005345416,-0.44272360620966467,1.2006123561295081,-0.2624316007781427,1.756913855622745,1.2398050154301583,1.1612911271561115,0.45095052821872006,0.63781871017397,2.938901920174116,-0.3973599555513764,1.0026952612052977,1.2788703326571973,4.919035001410219,4.371143071972117,-0.8602209755086283,-0.765957559026696,0.3668969742024014,-1.0032971173184342,0.2609348885354999,-0.06319602389665722,-0.5111409380756051,-0.24010992570608994,-0.6725623413977179,0.8419387390190867,-0.24010992570608994,0.45095052821872006,0.5758696256500044,0.3668969742024014,-0.8365724257127242,0.5551449816119026,1.4146133989581882,1.1020654814306523,0.1754315665029435,0.4927433790687372,-0.649346465031488,3.9466779732067017,-0.4654794845873636,-1.9357095033877805,-0.17342429277519616,-0.6725623413977179,0.1539519038710691,-0.5111409380756051,-0.21783500662433905,1.3566237550487579,-1.2711098312889768,1.6627764647279124,-0.17342429277519616,-0.019418398789169906,2.818437377950935,0.8216878926093156,-0.4654794845873636,1.5679201137609433,-0.5111409380756051,-1.051450154863121,-1.5211834842036118,-0.6958310323456385,-1.3953280732566287,-0.2624316007781427,3.294063684318148,1.6627764647279124,-0.3973599555513764,-0.3296800727932999,-1.4958783657412849,-0.28480032142736955,-1.221867139462494,-1.2464572039127382,1.2398050154301583,1.0822579505106387,0.34578486103996076,0.5965566621544192,1.1020654814306523,0.5343825284198839,-0.37475155706455276,0.5965566621544192,0.23962088616631888,0.08925988661092682,-0.765957559026696,0.740329474853222,0.8823351884307354,3.2103258670728594,0.9024811471197746,-0.5570041480733425,-0.3296800727932999,0.02418316160624745,0.08925988661092682,-0.4200172014503317,0.42999594114352935,0.7607227005345416,-0.21783500662433905,0.11086630745425535,-0.979308054094136,0.8621544447614617,4.10531535914725,-0.10715181947123369,-0.28480032142736955,-0.10715181947123369,0.5965566621544192,-0.2624316007781427,0.5135820626533416,-0.6261830525123374,-0.6958310323456385,-0.37475155706455276,0.3034406273252866,0.32463281965659274,-0.04128507261807166,0.7199001923772445,2.4504202205674956,1.042543447000245,1.8875282907253164,0.63781871017397,-0.6725623413977179,-0.04128507261807166,3.4270086253384453,1.3953142204299533,-0.12919720072059518,-0.7894410947493521,0.6172062909671789,-0.1956065568925503,0.8216878926093156,-0.2624316007781427,1.2398050154301583,1.0226361470657186,0.1968694596042953,-0.3521916978029156,-0.649346465031488,0.5343825284198839,0.02418316160624745,1.3372321800117861,3.3440660042253465,-0.1956065568925503,-0.15128793340057795,0.7607227005345416,0.1539519038710691,0.5551449816119026,0.04591856434758408,-0.5340471596998287,-0.5111409380756051,1.6249211030705555,0.5343825284198839,-0.12919720072059518,-0.6261830525123374,0.6172062909671789,-0.2624316007781427,0.34578486103996076,-1.2464572039127382,-0.28480032142736955,3.7862935365121144,-0.37475155706455276,-1.5211834842036118,-0.019418398789169906,0.3034406273252866,0.63781871017397,0.4927433790687372,0.6172062909671789,-0.48828515470051204,0.13243023164297438,0.2609348885354999,0.13243023164297438,-0.37475155706455276,-1.470640789074526,1.042543447000245,0.45095052821872006,0.04591856434758408,1.1809678903438237,-0.3973599555513764,-0.1956065568925503,0.3668969742024014,3.9466779732067017,3.360693802938071,0.5343825284198839,0.13243023164297438,0.5965566621544192,0.6583941161256206,-0.1956065568925503,-0.37475155706455276,-1.0032971173184342,1.1020654814306523,-0.4654794845873636,-1.8303148472046438,0.002404259502052453,1.1020654814306523,0.7810800557959103,-0.06319602389665722,-0.1956065568925503,-0.17342429277519616,0.1754315665029435,-0.4654794845873636,2.235426922202329,0.34578486103996076,-0.21783500662433905,0.34578486103996076,0.6994346651191702,0.9827206223582612,-0.2624316007781427,1.2788703326571973,1.2788703326571973,0.4927433790687372,1.1612911271561115,0.32463281965659274
3,381
Cristae formation
6
20
2.251963
0.024325
P00846,O75964,Q13505,P17152,Q9NX63,P06576
Processes and pathways
Reactome Pathways
msigdb_reactome
32,39,9,484,342,433
1028,1631,39,32,433,484,591,2670,1571,3200,3268,1125,1574,9,982,1588,1735,1245,342,2042
0.2609348885354999,-0.08515151713377264,3.294063684318148,3.377301896133515,0.9024811471197746,0.8216878926093156,0.6583941161256206,-0.6261830525123374,-0.04128507261807166,-1.221867139462494,-1.4203661597491495,0.1968694596042953,-0.04128507261807166,4.10531535914725,0.3034406273252866,-0.04128507261807166,-0.12919720072059518,0.13243023164297438,1.1020654814306523,-0.2624316007781427
3,381
ATP synthase
12
21
2.246232
0.024689
P00846,Q9UI12,O75964,Q9Y487,Q9Y5K8,Q93050,P06576,Q15904,P24539,Q96IX5,Q6IN85,P21281
Functions
Panther Protein class
panther_protein_class
32,877,39,74,516,46,433,897,591,870,475,721
1631,39,32,433,721,2906,591,2670,1571,1295,3268,1125,1574,919,897,475,46,870,877,74,516
-0.08515151713377264,3.294063684318148,3.377301896133515,0.9024811471197746,0.5135820626533416,-0.8129792586013125,0.6583941161256206,-0.6261830525123374,-0.04128507261807166,0.08925988661092682,-1.4203661597491495,0.1968694596042953,-0.04128507261807166,0.34578486103996076,0.3668969742024014,0.8419387390190867,3.22711382314657,0.3879693798278019,0.3879693798278019,2.5389712897634884,0.7810800557959103
3,381
Hemiparesis
6
17
2.233366
0.025525
P31749,O00429,Q9NZ08,P00403,P03886,O60313
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
167,296,43,324,15,264
296,264,324,1847,15,1001,167,1392,3284,1336,1852,338,2060,3321,728,2254,43
1.2006123561295081,1.2788703326571973,1.1218400811435874,-0.1956065568925503,3.9466779732067017,0.28220805924936154,1.6627764647279124,0.04591856434758408,-1.4958783657412849,0.06761072205801114,-0.1956065568925503,1.1020654814306523,-0.28480032142736955,-1.752059420069416,0.5135820626533416,-0.37475155706455276,3.243881511379576
3,381
Limb muscle weakness
32
85
2.232645
0.025572
Q9BTV4,Q7RTS9,Q9Y5P6,Q9Y4W6,P31483,P46976,P50570,Q8WXH0,P00846,P05023,P31749,O60333,Q9NR77,Q9BQT8,Q8TB36,Q14739,Q8N0X7,Q8IY17,Q13501,Q14203,Q13126,Q969G3,P35609,Q99720,O75298,P07196,P06753,Q7Z406,Q15067,P02545,Q96BR5,P50402
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
776,2,666,399,646,648,651,289,32,540,167,297,42,693,691,445,574,317,457,706,73,728,349,97,348,100,357,486,108,739,500,244
2729,761,1562,2268,297,348,1433,32,739,2996,540,357,100,2979,2798,3224,1518,2095,2569,646,167,1392,349,2137,1675,2099,2571,2710,648,2573,1763,244,651,1955,2773,1123,1956,2233,3106,1767,1957,2189,1730,1812,3321,73,457,3190,2459,706,2779,2810,445,1532,108,2343,1686,2650,1586,952,3206,2425,2,486,928,317,574,691,289,1453,728,820,500,2027,1873,2720,97,693,776,42,2949,2823,399,666,2397
-0.6725623413977179,0.47186627057669517,-0.04128507261807166,-0.3973599555513764,1.2006123561295081,1.0822579505106387,0.02418316160624745,3.377301896133515,0.4927433790687372,-0.9076857627441651,0.740329474853222,1.0624173267017085,2.181118763924772,-0.8839252917779894,-0.7191528925187254,-1.2711098312889768,-0.019418398789169906,-0.30721638022967535,-0.5570041480733425,0.5965566621544192,1.6627764647279124,0.04591856434758408,1.0822579505106387,-0.3296800727932999,-0.10715181947123369,-0.30721638022967535,-0.5570041480733425,-0.649346465031488,0.5965566621544192,-0.5570041480733425,-0.15128793340057795,1.3372321800117861,0.5965566621544192,-0.24010992570608994,-0.6958310323456385,0.1968694596042953,-0.24010992570608994,-0.37475155706455276,-1.0273443454433155,-0.15128793340057795,-0.24010992570608994,-0.3521916978029156,-0.12919720072059518,-0.17342429277519616,-1.752059420069416,2.5389712897634884,0.8621544447614617,-1.1973391736481231,-0.48828515470051204,0.5343825284198839,-0.6958310323456385,-0.7191528925187254,0.8823351884307354,-0.019418398789169906,2.1265811273519164,-0.4200172014503317,-0.10715181947123369,-0.603071756954555,-0.04128507261807166,0.32463281965659274,-1.221867139462494,-0.4654794845873636,5.706293515755285,0.8216878926093156,0.34578486103996076,1.1612911271561115,0.6994346651191702,0.5551449816119026,1.2398050154301583,0.02418316160624745,0.5135820626533416,0.42999594114352935,0.8014017254185795,-0.2624316007781427,-0.1956065568925503,-0.649346465031488,2.235426922202329,0.5551449816119026,0.47186627057669517,3.243881511379576,-0.8365724257127242,-0.7191528925187254,0.9827206223582612,0.5965566621544192,-0.44272360620966467
3,381
Plasma membrane organization
10
32
2.22783
0.025892
O43633,P10909,P31749,P31751,Q9UQB8,P16615,P35579,Q16739,Q8N3R9,Q01082
Processes and pathways
GO Biological process
msigdb_gobp
256,166,167,7,202,241,371,25,385,444
256,1754,1565,166,241,167,7,371,1193,2493,651,444,2578,2062,1686,25,598,1012,1864,385,499,3089,2884,1070,2757,965,1838,202,2393,1747,1935,1425
1.2983556163200487,-0.15128793340057795,-0.04128507261807166,1.6627764647279124,1.3566237550487579,1.6627764647279124,4.1682935038480915,1.0226361470657186,0.1539519038710691,-0.5111409380756051,0.5965566621544192,0.8823351884307354,-0.5570041480733425,-0.28480032142736955,-0.10715181947123369,3.4930124961624522,0.6583941161256206,0.28220805924936154,-0.1956065568925503,1.0026952612052977,0.8014017254185795,-1.0032971173184342,-0.7894410947493521,0.23962088616631888,-0.6725623413977179,0.32463281965659274,-0.17342429277519616,1.5106544144638607,-0.44272360620966467,-0.12919720072059518,-0.21783500662433905,0.04591856434758408
3,381
Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen
9
35
2.224817
0.026094
Q16850,P09601,P30519,Q32P28,Q9BU89,Q6UW02,Q9UPP1,Q8IVL6,Q6PK18
Functions
GO Molecular function
msigdb_gomf
35,69,12,301,109,113,252,288,186
2600,1180,828,1027,1183,2792,577,1048,702,69,631,337,1635,12,653,1730,1773,925,526,35,301,2380,1310,186,113,2462,2350,288,771,109,3246,1623,1745,252,2597
-0.5800122352625738,0.1539519038710691,0.4090022965830154,0.2609348885354999,0.1539519038710691,-0.7191528925187254,0.6789327034592646,0.23962088616631888,0.5343825284198839,2.6269341644334787,0.6172062909671789,1.1020654814306523,-0.08515151713377264,4.026211556527206,0.5965566621544192,-0.12919720072059518,-0.15128793340057795,0.34578486103996076,0.7607227005345416,3.360693802938071,1.2006123561295081,-0.44272360620966467,0.08925988661092682,1.5679201137609433,2.053502337953164,-0.48828515470051204,-0.4200172014503317,1.2398050154301583,0.47186627057669517,2.0900937986973496,-1.3206046610312334,-0.06319602389665722,-0.12919720072059518,1.3372321800117861,-0.5570041480733425
3,381
Proto-oncogene
13
46
2.221853
0.026293
Q92804,P06753,Q9NZQ3,P31749,P31751,Q5M775,Q06136,P35637,Q03164,Q01105,Q01844,Q8WY22,Q16204
Drugs and Diseases
Protein Atlas Disease involvement
protein_atlas_disease_involvement
226,357,398,167,7,327,107,242,17,51,245,55,94
2445,1254,1081,2829,357,2179,2954,2407,578,1294,1948,167,7,2134,242,1608,1721,1636,1195,2674,917,2496,2187,51,245,17,1341,107,2876,2193,2009,657,94,327,55,1453,226,2627,3339,2208,2385,3154,1411,1368,449,398
-0.48828515470051204,0.11086630745425535,0.2182658209724741,-0.7425282805304556,1.0624173267017085,-0.3521916978029156,-0.8602209755086283,-0.4654794845873636,0.6789327034592646,0.08925988661092682,-0.24010992570608994,1.6627764647279124,4.1682935038480915,-0.3296800727932999,1.3566237550487579,-0.06319602389665722,-0.12919720072059518,-0.08515151713377264,0.1539519038710691,-0.6261830525123374,0.34578486103996076,-0.5111409380756051,-0.3521916978029156,3.1429699146944947,1.3372321800117861,3.898748651222953,0.06761072205801114,2.1265811273519164,-0.7894410947493521,-0.3521916978029156,-0.2624316007781427,0.5965566621544192,2.271506265376009,1.1218400811435874,3.0242997241481966,0.02418316160624745,1.3953142204299533,-0.5800122352625738,-2.0155688273638632,-0.3521916978029156,-0.44272360620966467,-1.0998392081028667,0.04591856434758408,0.06761072205801114,0.8823351884307354,0.9827206223582612
3,381
K Homology domain, type 1 [IPR004088]
12
26
2.217026
0.026621
O75525,Q92945,Q9Y6M1,Q9UNW9,Q9Y2W6,Q07666,P61978,Q13868,Q96PU8,P51116,Q96I24,Q96AE4
Sequence
InterPro Domain
interpro_domain
465,773,333,535,567,655,339,85,216,652,514,354
2087,1471,465,1050,652,1765,339,1443,794,655,85,2684,1777,1446,1973,2540,2072,773,354,514,216,2032,1216,535,567,333
-0.30721638022967535,0.002404259502052453,0.8419387390190867,0.23962088616631888,0.5965566621544192,-0.15128793340057795,1.1020654814306523,0.02418316160624745,0.45095052821872006,0.5965566621544192,2.379148008871439,-0.6261830525123374,-0.15128793340057795,0.02418316160624745,-0.24010992570608994,-0.5340471596998287,-0.28480032142736955,0.47186627057669517,1.0822579505106387,0.7810800557959103,1.433882064981485,-0.2624316007781427,0.1539519038710691,0.7607227005345416,0.7199001923772445,1.1218400811435874
3,381
Endoplasmic reticulum golgi intermediate compartment
19
53
2.207556
0.027275
Q9BVK6,P30533,Q9Y282,P49257,Q13190,P80303,P24390,Q9Y3A6,Q08379,Q15363,P33908,O95070,Q03518,Q8N511,P49755,Q10472,P09429,Q8N3R9,O15260
Localization
GO Cellular component
msigdb_gocc
661,391,14,649,525,20,31,699,300,436,53,432,315,83,470,359,496,385,125
1329,125,1109,2270,432,702,496,31,2280,391,53,649,470,2676,1298,2494,3201,916,2142,20,1645,315,1960,300,359,1484,525,1963,746,2194,436,897,1132,1971,385,83,987,1869,3044,820,2432,1236,661,1411,1069,2037,994,2391,1326,14,699,1328,1075
0.06761072205801114,1.9060774234559776,0.1968694596042953,-0.3973599555513764,0.9024811471197746,0.5343825284198839,0.8014017254185795,3.393890352280565,-0.3973599555513764,0.9827206223582612,3.0922365590874046,0.5965566621544192,0.8419387390190867,-0.6261830525123374,0.08925988661092682,-0.5111409380756051,-1.221867139462494,0.34578486103996076,-0.3296800727932999,3.6241042724046744,-0.08515151713377264,1.1612911271561115,-0.24010992570608994,1.2006123561295081,1.0624173267017085,0.002404259502052453,0.7607227005345416,-0.24010992570608994,0.4927433790687372,-0.3521916978029156,0.9024811471197746,0.3668969742024014,0.1968694596042953,-0.24010992570608994,1.0026952612052977,2.3970023903006923,0.3034406273252866,-0.1956065568925503,-0.9553767442654298,0.42999594114352935,-0.4654794845873636,0.13243023164297438,0.5965566621544192,0.04591856434758408,0.23962088616631888,-0.2624316007781427,0.3034406273252866,-0.44272360620966467,0.08925988661092682,3.962619402550461,0.5551449816119026,0.08925988661092682,0.23962088616631888
3,381
Golgi stack
18
36
2.199959
0.02781
O95249,O00461,Q8WVQ1,Q9H4A5,P0CG08,Q10472,Q08379,O60763,Q9BZG1,Q9H4A6,Q8TBA6,Q15363,Q99996,Q10471,Q14789,Q10713,P98194,Q8NBZ7
Localization
GO Cellular component
msigdb_gocc
281,33,488,133,541,359,300,608,146,313,276,436,478,744,746,523,571,59
33,608,281,1671,541,2493,1298,1679,571,2059,2061,300,744,359,523,746,1615,436,2685,59,276,1820,488,2251,1066,3219,478,3048,146,133,313,1176,1466,3030,1665,783
3.360693802938071,0.63781871017397,1.2398050154301583,-0.10715181947123369,0.740329474853222,-0.5111409380756051,0.08925988661092682,-0.10715181947123369,0.6994346651191702,-0.28480032142736955,-0.28480032142736955,1.2006123561295081,0.4927433790687372,1.0624173267017085,0.7607227005345416,0.4927433790687372,-0.06319602389665722,0.9024811471197746,-0.6261830525123374,2.8357123156062505,1.2593535158381115,-0.17342429277519616,0.8216878926093156,-0.37475155706455276,0.23962088616631888,-1.2464572039127382,0.8419387390190867,-0.9553767442654298,1.7943710577317065,1.86895187853838,1.1809678903438237,0.1754315665029435,0.02418316160624745,-0.9315027811368324,-0.08515151713377264,0.47186627057669517
3,381
Inner mitochondrial membrane organization
9
22
2.194486
0.0282
O60220,Q9Y4W6,Q13505,Q9Y5J7,Q9Y5J9,P17152,O60313,Q5HYI7,Q9NX63
Processes and pathways
GO Biological process
msigdb_gobp
380,399,9,272,273,484,264,79,342
380,264,1028,1942,668,484,3200,9,982,560,79,1588,1735,1412,1245,342,3325,399,2042,272,273,759
1.0026952612052977,1.2788703326571973,0.2609348885354999,-0.24010992570608994,0.5758696256500044,0.8216878926093156,-1.221867139462494,4.10531535914725,0.3034406273252866,0.7199001923772445,2.4504202205674956,-0.04128507261807166,-0.12919720072059518,0.04591856434758408,0.13243023164297438,1.1020654814306523,-1.8303148472046438,0.9827206223582612,-0.2624316007781427,1.2788703326571973,1.2788703326571973,0.4927433790687372
3,381
Calcium mediated signaling
6
23
2.190958
0.028455
P78417,P0DP25,P16615,O75844,P42858,P00813
Processes and pathways
GO Biological process
msigdb_gobp
44,240,241,239,285,60
239,1081,60,911,240,241,2736,1715,2490,1570,1336,285,704,1298,44,393,1911,2539,1209,1170,2432,3196,2391
1.3566237550487579,0.2182658209724741,2.818437377950935,0.34578486103996076,1.3566237550487579,1.3566237550487579,-0.6725623413977179,-0.12919720072059518,-0.5111409380756051,-0.04128507261807166,0.06761072205801114,1.2398050154301583,0.5343825284198839,0.08925988661092682,3.22711382314657,0.9827206223582612,-0.21783500662433905,-0.5340471596998287,0.1539519038710691,0.1754315665029435,-0.4654794845873636,-1.1973391736481231,-0.44272360620966467
3,381
Scotoma
7
14
2.190935
0.028457
P00846,O60220,O00429,P03886,Q8WWV3,O60313,Q9H6K4
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
32,380,296,15,143,264,319
296,2635,380,264,882,32,15,1671,2803,143,3207,802,319,536
1.2006123561295081,-0.603071756954555,1.0026952612052977,1.2788703326571973,0.3668969742024014,3.377301896133515,3.9466779732067017,-0.10715181947123369,-0.7191528925187254,1.8130577786414614,-1.221867139462494,0.45095052821872006,1.1612911271561115,0.7607227005345416
3,381
Inorganic anion transport
12
27
2.187416
0.028712
P55011,Q96S66,P0CG08,P30536,Q9Y6M7,O43681,P54105,Q9UBX3,Q9C0H2,P21796,Q9UHG3,P45880
Processes and pathways
GO Biological process
msigdb_gobp
508,329,541,40,172,518,373,121,249,185,62,350
1179,518,1151,541,185,999,40,2417,350,1438,2141,373,508,2713,2190,598,3336,1658,329,249,2753,121,62,1421,3012,2519,172
0.1539519038710691,0.7607227005345416,0.1754315665029435,0.740329474853222,1.5679201137609433,0.28220805924936154,3.294063684318148,-0.4654794845873636,1.0822579505106387,0.02418316160624745,-0.3296800727932999,1.0226361470657186,0.7810800557959103,-0.649346465031488,-0.3521916978029156,0.6583941161256206,-1.9888702495275368,-0.08515151713377264,1.1218400811435874,1.3372321800117861,-0.6725623413977179,1.9615623146195156,2.818437377950935,0.04591856434758408,-0.9076857627441651,-0.5111409380756051,1.6438632266775426
3,381
Intracellular calcium-sensing protein
11
17
2.169209
0.030067
Q99584,P0DP25,Q8IYU8,Q9BRK5,P80303,Q15293,Q14257,O43852,P60660,P41208,Q9BPX6
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
710,240,176,638,20,559,54,117,593,284,157
117,240,3329,284,593,1809,20,1645,54,559,3228,2426,176,708,710,157,638
2.016805866932396,1.3566237550487579,-1.909245977734405,1.2398050154301583,0.6583941161256206,-0.17342429277519616,3.6241042724046744,-0.08515151713377264,3.041315484994378,0.7199001923772445,-1.2711098312889768,-0.4654794845873636,1.6059499638802452,0.5343825284198839,0.5343825284198839,1.700516799454386,0.6172062909671789
3,381
Calmodulin
11
17
2.169209
0.030067
Q99584,P0DP25,Q8IYU8,Q9BRK5,P80303,Q15293,Q14257,O43852,P60660,P41208,Q9BPX6
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
710,240,176,638,20,559,54,117,593,284,157
117,240,3329,284,593,1809,20,1645,54,559,3228,2426,176,708,710,157,638
2.016805866932396,1.3566237550487579,-1.909245977734405,1.2398050154301583,0.6583941161256206,-0.17342429277519616,3.6241042724046744,-0.08515151713377264,3.041315484994378,0.7199001923772445,-1.2711098312889768,-0.4654794845873636,1.6059499638802452,0.5343825284198839,0.5343825284198839,1.700516799454386,0.6172062909671789
3,381
Muscle contraction
10
27
2.1608
0.030711
P35609,P06753,P05023,O43865,Q13555,P08670,P16615,Q99996,P09493,P67936
Processes and pathways
Reactome Pathways
msigdb_reactome
349,357,540,203,595,77,241,478,87,214
203,2485,540,911,357,2404,1565,77,87,241,2736,1391,1116,1522,2097,349,2372,593,214,838,1773,1007,595,2581,478,824,1799
1.4915063959259396,-0.5111409380756051,0.740329474853222,0.34578486103996076,1.0624173267017085,-0.4654794845873636,-0.04128507261807166,2.4681780465301033,2.3433660052850382,1.3566237550487579,-0.6725623413977179,0.04591856434758408,0.1968694596042953,-0.019418398789169906,-0.30721638022967535,1.0822579505106387,-0.44272360620966467,0.6583941161256206,1.433882064981485,0.4090022965830154,-0.15128793340057795,0.28220805924936154,0.6583941161256206,-0.5570041480733425,0.8419387390190867,0.42999594114352935,-0.15128793340057795
3,381
Prostate cancer
7
17
2.153825
0.031254
P31749,P49841,P31751,P16220,O15111,P62993,P27361
Processes and pathways
KEGG Pathways
msigdb_kegg
167,704,7,336,812,723,941
812,1081,1802,1189,1672,1331,336,974,941,1256,167,7,1335,1336,704,723,1577
0.42999594114352935,0.2182658209724741,-0.17342429277519616,0.1539519038710691,-0.10715181947123369,0.06761072205801114,1.1020654814306523,0.3034406273252866,0.32463281965659274,0.11086630745425535,1.6627764647279124,4.1682935038480915,0.06761072205801114,0.06761072205801114,0.5343825284198839,0.5135820626533416,-0.04128507261807166
3,381
Metal ion homeostasis
25
81
2.146366
0.031844
P55011,P62942,Q9Y4W6,P30519,Q96A33,P42858,Q8NEW0,Q9BPX6,Q9Y5X3,Q96TC7,P05023,Q9HC07,P78417,Q8IYU8,P98194,P09601,Q9Y487,Q8N511,Q9HD20,O75880,Q6P4Q7,P0DP25,P16615,P09429,Q9NWR8
Processes and pathways
GO Biological process
msigdb_gobp
508,382,399,12,268,285,412,157,554,426,540,171,44,176,571,69,74,83,89,466,362,240,241,496,250
2359,2173,1429,2268,1184,589,1752,466,3280,860,668,2733,2705,3331,2602,540,911,1082,3358,2954,1565,496,69,240,1191,1331,241,2736,1715,1116,2096,3121,2280,1570,12,2097,1295,285,1298,2418,2372,508,919,1339,382,44,571,1302,817,2062,2193,2340,1615,897,982,362,1162,1268,2539,176,83,800,1209,412,268,2544,2472,426,157,3046,3111,1983,171,89,3196,250,1837,2927,74,399,554
-0.44272360620966467,-0.3521916978029156,0.02418316160624745,-0.3973599555513764,0.1539519038710691,0.6583941161256206,-0.15128793340057795,0.8419387390190867,-1.470640789074526,0.3879693798278019,0.5758696256500044,-0.6725623413977179,-0.649346465031488,-1.9357095033877805,-0.5800122352625738,0.740329474853222,0.34578486103996076,0.2182658209724741,-2.595820943289011,-0.8602209755086283,-0.04128507261807166,0.8014017254185795,2.6269341644334787,1.3566237550487579,0.1539519038710691,0.06761072205801114,1.3566237550487579,-0.6725623413977179,-0.12919720072059518,0.1968694596042953,-0.30721638022967535,-1.051450154863121,-0.3973599555513764,-0.04128507261807166,4.026211556527206,-0.30721638022967535,0.08925988661092682,1.2398050154301583,0.08925988661092682,-0.4654794845873636,-0.44272360620966467,0.7810800557959103,0.34578486103996076,0.06761072205801114,1.0026952612052977,3.22711382314657,0.6994346651191702,0.08925988661092682,0.42999594114352935,-0.28480032142736955,-0.3521916978029156,-0.4200172014503317,-0.06319602389665722,0.3668969742024014,0.3034406273252866,1.0624173267017085,0.1754315665029435,0.11086630745425535,-0.5340471596998287,1.6059499638802452,2.3970023903006923,0.45095052821872006,0.1539519038710691,0.9426694105267227,1.2788703326571973,-0.5340471596998287,-0.48828515470051204,0.9225924964376042,1.700516799454386,-0.9553767442654298,-1.0273443454433155,-0.24010992570608994,1.6438632266775426,2.3433660052850382,-1.1973391736481231,1.3372321800117861,-0.17342429277519616,-0.8129792586013125,2.5389712897634884,0.9827206223582612,0.740329474853222
3,381
Sensorimotor neuropathy
9
33
2.144983
0.031954
P00846,Q9Y2R0,P07196,O00429,Q9NR77,P00403,P03886,O60313,O95831
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
32,99,100,296,42,324,15,264,219
296,1562,264,1077,219,324,32,15,540,100,611,1083,3147,2769,2099,2571,1193,1953,2140,2233,3106,1812,948,2343,3242,1135,1453,2720,42,992,1072,99,399
1.2006123561295081,-0.04128507261807166,1.2788703326571973,0.2182658209724741,1.4146133989581882,1.1218400811435874,3.377301896133515,3.9466779732067017,0.740329474853222,2.181118763924772,0.63781871017397,0.2182658209724741,-1.0998392081028667,-0.6958310323456385,-0.30721638022967535,-0.5570041480733425,0.1539519038710691,-0.24010992570608994,-0.3296800727932999,-0.37475155706455276,-1.0273443454433155,-0.17342429277519616,0.32463281965659274,-0.4200172014503317,-1.3206046610312334,0.1968694596042953,0.02418316160624745,-0.649346465031488,3.243881511379576,0.3034406273252866,0.23962088616631888,2.235426922202329,0.9827206223582612
3,381
Cytochrome complex assembly
8
14
2.140952
0.032278
O75880,Q9Y2R0,Q6DKK2,Q8N8Q8,Q9BSK2,Q69YU5,Q9NVA1,Q9BRT2
Processes and pathways
GO Biological process
msigdb_gobp
466,99,225,528,639,28,715,623
2268,466,915,1087,2063,28,225,528,623,754,639,715,2442,99
-0.3973599555513764,0.8419387390190867,0.34578486103996076,0.2182658209724741,-0.28480032142736955,3.4270086253384453,1.3953142204299533,0.7607227005345416,0.63781871017397,0.4927433790687372,0.6172062909671789,0.5343825284198839,-0.4654794845873636,2.235426922202329
3,381