term
stringlengths
2
121
overlap
int64
6
281
setsize
int64
7
499
score
float64
1.96
10.6
pval
float64
0
0.05
edge
stringlengths
41
1.97k
type
stringclasses
5 values
subtype
stringclasses
24 values
subtype_key
stringclasses
24 values
edge_idxs
stringlengths
11
1.17k
ann_idxs
stringlengths
19
2.31k
ann_vals
stringlengths
124
9.94k
sig_size
int64
2.2k
3.73k
Protein kinase complex
14
27
2.818143
0.00483
P50750,Q00534,Q9P287,P11802,O15111,P14635,Q92759,P49736,Q9NYV4,P12004,Q93100,P54646,P13010,Q00535
Localization
GO Cellular component
msigdb_gocc
611,188,278,555,652,713,478,609,454,500,953,568,848,569
652,2113,1356,1190,555,500,918,848,2075,713,1062,1754,1365,609,611,1518,568,1320,188,569,1926,478,953,1671,454,278,2006
0.794898196074666,-0.4156376825645661,0.2693890486299308,0.41375298229412827,0.8893530432986828,0.9364602576476364,0.6050042976186534,0.6526028648357912,-0.366054672771204,0.7475489758869491,0.5095518305985256,-0.07070541701478243,0.2693890486299308,0.842165951616307,0.842165951616307,0.12420299769392679,0.8893530432986828,0.3176003848945597,1.4033026844567509,0.8893530432986828,-0.2179206085639643,0.9834883672939752,0.6050042976186534,0.02694194594229031,1.030438131327194,1.2640374297013774,-0.2671955040084828
3,216
Il3 signaling pathway
7
12
2.807108
0.004999
Q06124,P40763,P22681,P12931,P27348,P46109,P31946
Processes and pathways
WikiPathways
msigdb_wp
676,262,285,283,505,58,183
2117,283,1132,285,505,1475,183,262,58,1524,675,676
-0.4156376825645661,1.2174684580139272,0.4616961579572844,1.2174684580139272,0.9364602576476364,0.17269137095443782,1.4033026844567509,1.2640374297013774,1.8629293399977658,0.12420299769392679,0.794898196074666,0.794898196074666
3,216
Formation of tubulin folding intermediates by cct tric
11
12
2.791891
0.00524
Q9BUF5,P50991,Q13885,P40227,Q99832,P50990,P17987,P48643,P04350,P78371,P68371
Processes and pathways
Reactome Pathways
msigdb_reactome
640,863,804,931,1036,565,502,670,255,734,733
255,502,931,670,995,565,863,733,734,804,1036,640
1.2640374297013774,0.9364602576476364,0.6050042976186534,0.794898196074666,0.5573209122218296,0.8893530432986828,0.6526028648357912,0.7475489758869491,0.7475489758869491,0.7001174756266921,0.5573209122218296,0.842165951616307
3,216
Genes related to primary cilium development based on crispr
8
14
2.791711
0.005243
Q6UVJ0,Q9H0F7,Q8IW35,Q9BW83,Q9ULC3,Q9Y547,Q8NCM8,Q7Z392
Processes and pathways
WikiPathways
msigdb_wp
102,34,629,583,490,137,630,473
795,2082,1318,2363,102,473,629,630,583,34,1544,490,651,137
0.7001174756266921,-0.366054672771204,0.3176003848945597,-0.6650560527011644,1.6799041353764064,0.9834883672939752,0.842165951616307,0.842165951616307,0.8893530432986828,2.0902274206098244,0.12420299769392679,0.9834883672939752,0.842165951616307,1.5879835753717237
3,216
Phenol containing compound metabolic process
7
14
2.791573
0.005245
O14908,P00492,Q9UKG1,P58546,P30046,P16930,Q99497
Processes and pathways
GO Biological process
msigdb_gobp
457,553,79,388,205,422,301
457,553,2209,2210,422,1964,205,388,1148,1530,638,301,79,1743
0.9834883672939752,0.8893530432986828,-0.5151066365455765,-0.5151066365455765,1.030438131327194,-0.2671955040084828,1.3569538751932833,1.077310295637479,0.4616961579572844,0.12420299769392679,0.842165951616307,1.2174684580139272,1.7715511827549129,-0.021832892459727565
3,216
ubiquitin-protein ligase
33
67
2.780381
0.00543
Q9NT62,O95155,Q8TDB6,Q9UBE0,Q86UK7,O75155,Q7Z7E8,Q13619,Q99816,Q9H944,P61086,P38398,P61088,Q92990,Q8IWV7,P22314,Q13616,Q5T447,Q9Y263,P63208,Q53EP0,Q05086,Q7Z6Z7,P68036,O95376,O95352,Q15386,Q13564,Q93034,Q9UBT2,Q9HB71,Q8TBC4,A0AVT1
Functions
Panther Protein class
panther_protein_class
276,7,8,153,396,251,810,679,24,694,513,508,294,580,445,663,437,190,595,430,324,433,747,322,551,310,742,738,364,648,536,400,597
597,1464,251,845,1749,2399,1625,7,310,551,2677,663,2465,508,939,513,294,1261,430,322,433,944,2512,1429,738,437,1269,1649,679,1585,1432,2172,742,324,1593,190,1328,2429,1334,747,810,396,1025,445,400,8,580,364,2913,2052,24,1398,2783,694,536,2145,276,153,648,833,2708,1679,1504,1109,595,2923,1235
0.842165951616307,0.17269137095443782,1.2640374297013774,0.6526028648357912,-0.07070541701478243,-0.7152351825377116,0.02694194594229031,3.116277872220779,1.1708247446272457,0.8893530432986828,-1.0183189340779024,0.794898196074666,-0.7655111190576772,0.9364602576476364,0.6050042976186534,0.9364602576476364,1.2174684580139272,0.36572137390740567,1.030438131327194,1.1708247446272457,1.030438131327194,0.6050042976186534,-0.8158831663999228,0.22108637922276436,0.7475489758869491,1.030438131327194,0.36572137390740567,0.02694194594229031,0.794898196074666,0.07562021229046627,0.22108637922276436,-0.4653219270618636,0.7475489758869491,1.1708247446272457,0.07562021229046627,1.4033026844567509,0.3176003848945597,-0.7152351825377116,0.3176003848945597,0.7475489758869491,0.7001174756266921,1.077310295637479,0.5573209122218296,1.030438131327194,1.077310295637479,3.072289711116106,0.8893530432986828,1.124105593246472,-1.324744331610297,-0.3165736808932445,2.225840718700203,0.2693890486299308,-1.1200961902344955,0.794898196074666,0.9364602576476364,-0.4156376825645661,1.2640374297013774,1.541919243533965,0.842165951616307,0.7001174756266921,-1.0183189340779024,0.02694194594229031,0.17269137095443782,0.5095518305985256,0.8893530432986828,-1.324744331610297,0.41375298229412827
3,216
Cyclin dependent protein kinase holoenzyme complex
8
12
2.767775
0.005644
P50750,Q00534,Q9P287,P11802,P49736,Q9NYV4,P12004,Q00535
Localization
GO Cellular component
msigdb_gocc
611,188,278,555,609,454,500,569
2113,1356,555,500,713,1365,609,611,188,569,454,278
-0.4156376825645661,0.2693890486299308,0.8893530432986828,0.9364602576476364,0.7475489758869491,0.2693890486299308,0.842165951616307,0.842165951616307,1.4033026844567509,0.8893530432986828,1.030438131327194,1.2640374297013774
3,216
Signaling by interleukins
64
108
2.76055
0.00577
Q13126,P51665,P51452,Q13200,P62333,P43686,P40763,P28070,Q9UNM6,O00232,P17987,P05388,P40222,P26038,P09429,O75832,P62195,Q99460,P48556,Q99436,Q53EL6,P61088,Q06124,P52907,O15111,Q02750,P25787,Q16539,P22681,P61289,Q13616,P78417,P20618,O00233,P46109,P35998,Q07820,P30153,P63208,O43242,P30154,P25789,Q92530,O00487,P28074,P49721,P28072,P60900,P55036,P37837,Q13177,Q15008,P25788,Q99439,P17980,Q06323,P28066,P11142,P25786,Q9UL46,P14174,P49720,O00231,P42224
Processes and pathways
Reactome Pathways
msigdb_reactome
0,725,865,622,617,510,262,506,412,248,502,256,20,504,257,384,389,959,511,958,31,294,676,292,652,675,156,574,285,177,437,51,786,414,58,667,189,666,430,548,182,181,751,773,791,187,925,937,428,930,875,877,560,89,716,100,465,712,719,119,349,358,838,856
1116,838,248,414,773,1050,2790,652,548,384,1909,3023,2458,256,2502,3160,2116,1302,2015,2117,2304,257,1809,1912,712,2073,349,2716,1132,716,502,786,3212,2986,285,1134,719,156,560,181,504,2505,465,506,925,791,1475,666,182,667,930,2121,20,262,856,1196,510,58,511,358,187,865,2873,725,1760,1141,292,428,937,1521,294,177,1003,389,617,1261,1524,1374,430,51,675,676,100,189,2994,2728,0,875,622,1429,437,1436,1771,877,1488,1867,1327,574,1020,31,751,958,89,959,1103,1456,119,412
0.4616961579572844,0.6526028648357912,1.2640374297013774,1.030438131327194,0.7001174756266921,0.5095518305985256,-1.1711224385842194,0.794898196074666,0.8893530432986828,1.077310295637479,-0.2179206085639643,-1.5825561231311243,-0.7655111190576772,1.2640374297013774,-0.8158831663999228,-2.1045905550594624,-0.4156376825645661,0.3176003848945597,-0.3165736808932445,-0.4156376825645661,-0.6149744369312105,1.2640374297013774,-0.11967676552251524,-0.2179206085639643,0.7475489758869491,-0.366054672771204,1.124105593246472,-1.0691614811317376,0.4616961579572844,0.7475489758869491,0.9364602576476364,0.7001174756266921,-3.8826837401113194,-1.4791685400274208,1.2174684580139272,0.4616961579572844,0.7475489758869491,1.4957847330195655,0.8893530432986828,1.4033026844567509,0.9364602576476364,-0.8158831663999228,0.9834883672939752,0.9364602576476364,0.6050042976186534,0.7001174756266921,0.17269137095443782,0.794898196074666,1.4033026844567509,0.794898196074666,0.6050042976186534,-0.4156376825645661,2.2709206091816405,1.2640374297013774,0.6526028648357912,0.41375298229412827,0.9364602576476364,1.8629293399977658,0.9364602576476364,1.124105593246472,1.4033026844567509,0.6526028648357912,-1.2734471088745247,0.7475489758869491,-0.07070541701478243,0.4616961579572844,1.2174684580139272,1.030438131327194,0.6050042976186534,0.12420299769392679,1.2174684580139272,1.4495794234747916,0.5573209122218296,1.077310295637479,0.842165951616307,0.36572137390740567,0.12420299769392679,0.2693890486299308,1.030438131327194,1.9085189906980928,0.794898196074666,0.794898196074666,1.6799041353764064,1.4033026844567509,-1.4791685400274208,-1.0691614811317376,9.177325366097879,0.6526028648357912,0.842165951616307,0.22108637922276436,1.030438131327194,0.22108637922276436,-0.07070541701478243,0.6526028648357912,0.17269137095443782,-0.1687481002224421,0.3176003848945597,0.8893530432986828,0.5573209122218296,2.1354946214911243,0.7475489758869491,0.6050042976186534,1.7257615558657298,0.6050042976186534,0.5095518305985256,0.22108637922276436,1.633978339030236,1.077310295637479
3,216
Toll like receptor 9 tlr9 cascade
8
18
2.757295
0.005828
P63208,P30154,P61088,O15111,Q02750,Q16539,Q13616,P09429
Processes and pathways
Reactome Pathways
msigdb_reactome
430,182,294,652,675,574,437,257
652,257,1475,666,182,865,294,430,675,1429,437,1436,1773,1488,1867,574,1884,2099
0.794898196074666,1.2640374297013774,0.17269137095443782,0.794898196074666,1.4033026844567509,0.6526028648357912,1.2174684580139272,1.030438131327194,0.794898196074666,0.22108637922276436,1.030438131327194,0.22108637922276436,-0.07070541701478243,0.17269137095443782,-0.1687481002224421,0.8893530432986828,-0.1687481002224421,-0.366054672771204
3,216
Negative regulation of peptidase activity
17
35
2.75076
0.005946
P54578,Q92530,Q9C0C9,Q9Y5K5,Q9NR09,P61201,Q13492,Q13464,P12931,P04080,Q13177,P30086,P06744,P20810,Q96K76,Q9NWS0,Q99497
Processes and pathways
GO Biological process
msigdb_gobp
123,751,642,378,644,615,208,468,283,312,875,221,499,259,892,761,301
1900,2540,312,1414,499,2116,2210,283,2404,259,1420,1756,221,1565,852,2023,1569,123,615,1863,875,468,208,2173,1715,1488,3134,751,892,301,642,644,1106,761,378
-0.2179206085639643,-0.8663506399354521,1.1708247446272457,0.22108637922276436,0.9364602576476364,-0.4156376825645661,-0.5151066365455765,1.2174684580139272,-0.7152351825377116,1.2640374297013774,0.22108637922276436,-0.07070541701478243,1.3105323443353172,0.07562021229046627,0.6526028648357912,-0.3165736808932445,0.07562021229046627,1.5879835753717237,0.842165951616307,-0.1687481002224421,0.6526028648357912,0.9834883672939752,1.3569538751932833,-0.4653219270618636,-0.021832892459727565,0.17269137095443782,-1.8947739810490956,0.7475489758869491,0.6526028648357912,1.2174684580139272,0.842165951616307,0.842165951616307,0.5095518305985256,0.7475489758869491,1.124105593246472
3,216
G1 to s cell cycle control
12
27
2.739582
0.006152
O43929,Q00534,P27694,P42771,P35244,P11802,P06400,P12004,P49643,P49642,P33991,P49736
Processes and pathways
WikiPathways
msigdb_wp
56,188,463,185,39,555,658,500,290,671,352,609
1688,56,2458,658,1356,555,500,713,1252,1365,1253,463,352,989,1516,39,185,671,290,609,1424,188,1266,1484,1528,3034,1346
-0.021832892459727565,1.8629293399977658,-0.7655111190576772,0.794898196074666,0.2693890486299308,0.8893530432986828,0.9364602576476364,0.7475489758869491,0.36572137390740567,0.2693890486299308,0.36572137390740567,0.9834883672939752,1.124105593246472,0.5573209122218296,0.12420299769392679,1.9995021737690988,1.4033026844567509,0.794898196074666,1.2174684580139272,0.842165951616307,0.22108637922276436,1.4033026844567509,0.36572137390740567,0.17269137095443782,0.12420299769392679,-1.5825561231311243,0.3176003848945597
3,216
ThiF/MoeB/HesA family [IPR045886]
6
8
2.736043
0.006218
P22314,Q9UBE0,O95352,Q9UBT2,Q8TBC4,A0AVT1
Sequence
InterPro Family
interpro_family
663,153,310,648,400,597
597,310,663,738,400,1398,153,648
0.842165951616307,1.1708247446272457,0.794898196074666,0.7475489758869491,1.077310295637479,0.2693890486299308,1.541919243533965,0.842165951616307
3,216
THIF-type NAD/FAD binding fold [IPR000594]
6
8
2.736043
0.006218
P22314,Q9UBE0,O95352,Q9UBT2,Q8TBC4,A0AVT1
Sequence
InterPro Domain
interpro_domain
663,153,310,648,400,597
597,310,663,738,400,1398,153,648
0.842165951616307,1.1708247446272457,0.794898196074666,0.7475489758869491,1.077310295637479,0.2693890486299308,1.541919243533965,0.842165951616307
3,216
Ubiquitin like modifier activating enzyme activity
6
8
2.736043
0.006218
P22314,Q9UBE0,O95352,Q9UBT2,Q8TBC4,A0AVT1
Functions
GO Molecular function
msigdb_gomf
663,153,310,648,400,597
597,310,663,738,400,1398,153,648
0.842165951616307,1.1708247446272457,0.794898196074666,0.7475489758869491,1.077310295637479,0.2693890486299308,1.541919243533965,0.842165951616307
3,216
Ubiquitin-activating enzyme [IPR035985]
6
8
2.736043
0.006218
P22314,Q9UBE0,O95352,Q9UBT2,Q8TBC4,A0AVT1
Sequence
InterPro Superfamily
interpro_homologous_superfamily
663,153,310,648,400,597
597,310,663,738,400,1398,153,648
0.842165951616307,1.1708247446272457,0.794898196074666,0.7475489758869491,1.077310295637479,0.2693890486299308,1.541919243533965,0.842165951616307
3,216
Mismatch repair
9
13
2.728698
0.006358
Q15054,P27694,P35244,P12004,P09429,Q9UQ84,O75792,P43246,P52701
Processes and pathways
GO Biological process
msigdb_gobp
805,463,39,500,257,19,911,607,726
911,257,500,1252,1630,1418,463,39,607,726,936,805,19
0.6050042976186534,1.2640374297013774,0.9364602576476364,0.36572137390740567,0.02694194594229031,0.22108637922276436,0.9834883672939752,1.9995021737690988,0.842165951616307,0.7475489758869491,0.6050042976186534,0.7001174756266921,2.31593904512126
3,216
Translation factor activity rna binding
36
56
2.719164
0.006545
P62495,O15372,P05198,P41091,Q7L2H7,Q04637,Q05639,Q92616,Q9BY44,O00303,Q9NR50,P41567,P55010,Q92905,O43432,P06730,Q9Y262,P26641,O43583,O60573,P29692,O75822,O00178,P13639,Q14240,P57772,P60228,Q9Y450,Q14232,Q9UBQ5,P41214,P15170,Q13144,P24534,Q7Z2Z2,P60842
Functions
GO Molecular function
msigdb_gomf
618,978,1125,992,521,1007,147,952,823,494,967,33,293,447,778,915,1112,664,1053,1056,793,550,1047,556,876,1072,1073,906,1015,647,854,220,113,351,522,869
1047,494,1556,978,778,1053,1056,1845,1409,550,1125,915,556,220,1512,1364,351,664,793,992,854,33,3011,2633,2313,1198,293,1372,2163,1072,1073,869,618,1147,1648,1007,147,113,1268,1434,1982,1015,876,521,522,1879,952,447,2239,823,967,647,1796,1738,1112,906
0.5095518305985256,0.9364602576476364,0.07562021229046627,0.5573209122218296,0.7001174756266921,0.5095518305985256,0.5095518305985256,-0.1687481002224421,0.22108637922276436,0.8893530432986828,0.4616961579572844,0.6050042976186534,0.8893530432986828,1.3105323443353172,0.12420299769392679,0.2693890486299308,1.124105593246472,0.794898196074666,0.7001174756266921,0.5573209122218296,0.6526028648357912,2.0902274206098244,-1.5308188918515426,-0.9675691815600861,-0.6149744369312105,0.41375298229412827,1.2174684580139272,0.2693890486299308,-0.4653219270618636,0.5095518305985256,0.5095518305985256,0.6526028648357912,0.842165951616307,0.4616961579572844,0.02694194594229031,0.5573209122218296,1.541919243533965,1.633978339030236,0.36572137390740567,0.22108637922276436,-0.2671955040084828,0.5573209122218296,0.6526028648357912,0.9364602576476364,0.9364602576476364,-0.1687481002224421,0.6050042976186534,1.030438131327194,-0.5151066365455765,0.7001174756266921,0.6050042976186534,0.842165951616307,-0.07070541701478243,-0.021832892459727565,0.5095518305985256,0.6526028648357912
3,216
Microtubule cytoskeleton regulation
7
19
2.719068
0.006547
Q15691,P40763,Q13464,P12931,P46821,O60610,Q16555
Processes and pathways
WikiPathways
msigdb_wp
161,262,468,283,356,458,393
458,1356,283,920,1132,1511,262,356,1199,1521,1646,468,161,518,393,2230,1333,1281,1620
0.9834883672939752,0.2693890486299308,1.2174684580139272,0.6050042976186534,0.4616961579572844,0.12420299769392679,1.2640374297013774,1.124105593246472,0.41375298229412827,0.12420299769392679,0.02694194594229031,0.9834883672939752,1.4957847330195655,0.9364602576476364,1.077310295637479,-0.5151066365455765,0.3176003848945597,0.36572137390740567,0.07562021229046627
3,216
Netrin 1 signaling
7
12
2.715456
0.006618
Q06124,O00401,P15311,P12931,Q16539,P16333,Q16512
Processes and pathways
Reactome Pathways
msigdb_reactome
676,307,714,283,574,385,518
307,2112,283,714,385,1361,1521,1646,735,676,518,574
1.1708247446272457,-0.4156376825645661,1.2174684580139272,0.7475489758869491,1.077310295637479,0.2693890486299308,0.12420299769392679,0.02694194594229031,0.7475489758869491,0.794898196074666,0.9364602576476364,0.8893530432986828
3,216
Trna modification
26
42
2.69987
0.006937
Q9NXG2,Q96EB1,P05455,Q96FX7,P57081,Q13395,Q08J23,Q2VPK5,Q96BT7,Q9NWX6,O95163,O60294,Q96G46,Q5T6V5,Q7Z2T5,Q9H9T3,Q9NPF4,Q9BV44,Q7Z4G4,Q9UI30,Q9UBP6,Q9Y3C4,Q9NX74,Q6YHU6,Q9H974,Q6P1R4
Processes and pathways
GO Biological process
msigdb_gobp
539,403,121,954,998,945,391,296,38,969,779,172,72,68,745,483,484,755,474,107,106,377,645,231,1037,269
172,1690,779,121,1310,998,391,945,296,2811,68,2041,269,231,2276,745,474,1095,2485,38,403,954,72,1500,2570,1885,755,2385,2821,1037,483,2058,484,969,645,539,106,1548,107,3095,377,1182
1.4495794234747916,-0.021832892459727565,0.7001174756266921,1.5879835753717237,0.3176003848945597,0.5573209122218296,1.077310295637479,0.6050042976186534,1.2174684580139272,-1.1711224385842194,1.8172735893082128,-0.3165736808932445,1.2640374297013774,1.3105323443353172,-0.5649910544332091,0.7475489758869491,0.9834883672939752,0.5095518305985256,-0.7655111190576772,2.0448967765740447,1.077310295637479,0.6050042976186534,1.8172735893082128,0.17269137095443782,-0.8663506399354521,-0.1687481002224421,0.7475489758869491,-0.6650560527011644,-1.1711224385842194,0.5573209122218296,0.9834883672939752,-0.3165736808932445,0.9834883672939752,0.6050042976186534,0.842165951616307,0.9364602576476364,1.6799041353764064,0.12420299769392679,1.6799041353764064,-1.738283680672314,1.124105593246472,0.4616961579572844
3,216
Negative regulation of protein modification by small protein conjugation or removal
14
37
2.698584
0.006964
Q9UHD1,Q96FW1,Q92990,P62841,Q8TDB6,Q00535,Q9Y263,O95816,O60566,O60678,Q6DKJ4,Q9UL15,P62081,Q99497
Processes and pathways
GO Biological process
msigdb_gobp
305,104,580,85,8,569,595,421,602,138,163,171,59,301
1119,980,602,138,2399,1625,421,1251,986,2017,3194,1256,1565,2408,1421,669,1480,1202,59,1645,85,1861,569,1863,1821,2172,163,8,580,2380,104,301,2854,2195,305,171,595
0.4616961579572844,0.5573209122218296,0.842165951616307,1.541919243533965,-0.7152351825377116,0.02694194594229031,1.030438131327194,0.36572137390740567,0.5573209122218296,-0.3165736808932445,-2.4748813591361145,0.36572137390740567,0.07562021229046627,-0.7152351825377116,0.22108637922276436,0.794898196074666,0.17269137095443782,0.41375298229412827,1.8629293399977658,0.02694194594229031,1.7257615558657298,-0.1687481002224421,0.8893530432986828,-0.1687481002224421,-0.11967676552251524,-0.4653219270618636,1.4957847330195655,3.072289711116106,0.8893530432986828,-0.6650560527011644,1.6799041353764064,1.2174684580139272,-1.2222396128348902,-0.4653219270618636,1.2174684580139272,1.4957847330195655,0.8893530432986828
3,216
Toll like receptor cascades
10
25
2.691049
0.007123
P63208,P30154,P61088,Q06124,Q6SZW1,O15111,Q02750,Q16539,Q13616,P09429
Processes and pathways
Reactome Pathways
msigdb_reactome
430,182,294,676,70,652,675,574,437,257
652,2210,257,2716,1475,666,182,1069,865,294,430,675,676,1429,1710,437,1436,1773,1488,1867,574,70,1884,2099,1456
0.794898196074666,-0.5151066365455765,1.2640374297013774,-1.0691614811317376,0.17269137095443782,0.794898196074666,1.4033026844567509,0.5095518305985256,0.6526028648357912,1.2174684580139272,1.030438131327194,0.794898196074666,0.794898196074666,0.22108637922276436,-0.021832892459727565,1.030438131327194,0.22108637922276436,-0.07070541701478243,0.17269137095443782,-0.1687481002224421,0.8893530432986828,1.8172735893082128,-0.1687481002224421,-0.366054672771204,0.22108637922276436
3,216
Regulation of cellular protein catabolic process
60
89
2.690391
0.007137
P54578,O15372,P0DMV9,P63244,P60520,P43686,O15294,P62333,Q05397,P62191,P17612,P26038,O75832,Q86UE8,P62195,O75150,Q9UL15,P61086,P35241,Q99497,Q92990,Q96JB5,P78559,P19784,P61289,Q9UNE7,Q9C0D3,P10398,Q9Y4X5,Q9BW61,O94966,P48506,P08238,P35998,P62081,O95816,O14980,O00487,Q92530,Q05086,O95376,Q9H2J4,Q9H270,P55072,P49841,Q9UNN5,P46379,Q15370,Q96KB5,Q9Y5K5,O14908,Q96QK1,Q8NEZ5,P17980,Q06323,P15311,Q9UL46,O43765,Q9NZL4,P45974
Processes and pathways
GO Biological process
msigdb_gobp
123,978,1251,1262,124,510,1119,617,735,1003,1132,504,384,1090,389,1246,171,513,1137,301,580,1097,157,284,177,1109,588,783,1235,195,913,669,1059,667,59,421,547,773,751,433,551,756,482,1201,1199,491,1065,1019,236,378,457,638,1029,716,100,714,119,842,135,608
1460,773,457,1352,547,1119,978,842,1298,1246,384,1624,2399,913,551,421,2758,2116,1302,1059,1251,783,714,1132,716,284,1365,504,1137,667,510,608,1065,1421,669,1199,2026,1971,2081,123,1519,1201,124,513,177,59,1003,389,617,1645,1261,1861,1262,157,1863,433,735,100,2168,1433,1019,2734,1090,2325,1029,751,2741,580,1387,1391,1097,236,638,301,195,588,1608,482,756,1453,135,171,119,1504,1109,491,1235,1953,378
0.17269137095443782,0.7001174756266921,0.9834883672939752,0.2693890486299308,0.8893530432986828,0.4616961579572844,0.5573209122218296,0.6526028648357912,0.3176003848945597,0.36572137390740567,1.077310295637479,0.02694194594229031,-0.7152351825377116,0.6050042976186534,0.8893530432986828,1.030438131327194,-1.1200961902344955,-0.4156376825645661,0.3176003848945597,0.5095518305985256,0.36572137390740567,0.7001174756266921,0.7475489758869491,0.4616961579572844,0.7475489758869491,1.2174684580139272,0.2693890486299308,0.9364602576476364,0.4616961579572844,0.794898196074666,0.9364602576476364,0.842165951616307,0.5095518305985256,0.22108637922276436,0.794898196074666,0.41375298229412827,-0.3165736808932445,-0.2671955040084828,-0.366054672771204,1.5879835753717237,0.12420299769392679,0.41375298229412827,1.5879835753717237,0.9364602576476364,1.4495794234747916,1.8629293399977658,0.5573209122218296,1.077310295637479,0.842165951616307,0.02694194594229031,0.36572137390740567,-0.1687481002224421,0.36572137390740567,1.4957847330195655,-0.1687481002224421,1.030438131327194,0.7475489758869491,1.6799041353764064,-0.4653219270618636,0.22108637922276436,0.5573209122218296,-1.0691614811317376,0.5095518305985256,-0.6149744369312105,0.5573209122218296,0.7475489758869491,-1.0691614811317376,0.8893530432986828,0.2693890486299308,0.2693890486299308,0.5095518305985256,1.3105323443353172,0.842165951616307,1.2174684580139272,1.4033026844567509,0.8893530432986828,0.07562021229046627,0.9834883672939752,0.7475489758869491,0.22108637922276436,1.5879835753717237,1.4957847330195655,1.633978339030236,0.17269137095443782,0.5095518305985256,0.9834883672939752,0.41375298229412827,-0.2179206085639643,1.124105593246472
3,216
Regulation of protein modification by small protein conjugation or removal
37
86
2.690174
0.007141
P50750,Q9NW82,Q8TDB6,Q9UBE0,O75832,O60678,Q96GX5,Q6DKJ4,Q9UL15,Q99497,P38398,Q9UHD1,P61088,Q92990,O75340,Q9Y263,P48506,Q13309,O95816,Q00535,P62081,Q9BTE7,P63208,Q05086,Q01804,Q7Z6Z7,P68036,Q9UBV8,Q96DY7,Q9NVI1,P62841,Q96GG9,Q96FW1,P62942,Q9UBT2,O60566,Q9NZL4
Processes and pathways
GO Biological process
msigdb_gobp
611,411,8,153,384,138,300,163,171,301,508,305,294,580,654,595,669,570,421,569,59,754,430,433,323,747,322,214,480,486,85,235,104,98,648,602,135
1900,1119,980,2349,602,138,1246,654,845,384,1624,2399,1625,421,1302,1059,1251,919,986,2017,3194,1256,1565,2408,508,1421,669,611,1971,1201,1480,294,1202,59,1645,85,1261,1861,98,430,322,569,323,1863,433,737,1821,570,2226,1429,1014,1649,2172,1931,1329,163,1933,747,1939,8,580,2380,480,104,235,300,2913,1097,820,301,754,2056,2522,2854,486,2195,411,135,153,648,214,1547,305,171,1109,595
-0.2179206085639643,0.4616961579572844,0.5573209122218296,-0.6650560527011644,0.842165951616307,1.541919243533965,0.36572137390740567,0.794898196074666,0.6526028648357912,1.077310295637479,0.02694194594229031,-0.7152351825377116,0.02694194594229031,1.030438131327194,0.3176003848945597,0.5095518305985256,0.36572137390740567,0.6050042976186534,0.5573209122218296,-0.3165736808932445,-2.4748813591361145,0.36572137390740567,0.07562021229046627,-0.7152351825377116,0.9364602576476364,0.22108637922276436,0.794898196074666,0.842165951616307,-0.2671955040084828,0.41375298229412827,0.17269137095443782,1.2174684580139272,0.41375298229412827,1.8629293399977658,0.02694194594229031,1.7257615558657298,0.36572137390740567,-0.1687481002224421,1.6799041353764064,1.030438131327194,1.1708247446272457,0.8893530432986828,1.1708247446272457,-0.1687481002224421,1.030438131327194,0.7475489758869491,-0.11967676552251524,0.8893530432986828,-0.5151066365455765,0.22108637922276436,0.5573209122218296,0.02694194594229031,-0.4653219270618636,-0.2179206085639643,0.3176003848945597,1.4957847330195655,-0.2179206085639643,0.7475489758869491,-0.2179206085639643,3.072289711116106,0.8893530432986828,-0.6650560527011644,0.9834883672939752,1.6799041353764064,1.3105323443353172,1.2174684580139272,-1.324744331610297,0.5095518305985256,0.7001174756266921,1.2174684580139272,0.7475489758869491,-0.3165736808932445,-0.8158831663999228,-1.2222396128348902,0.9834883672939752,-0.4653219270618636,1.077310295637479,1.5879835753717237,1.541919243533965,0.842165951616307,1.3569538751932833,0.12420299769392679,1.2174684580139272,1.4957847330195655,0.5095518305985256,0.8893530432986828
3,216
Toll like receptor tlr1 tlr2 cascade
8
16
2.679159
0.007381
P63208,P30154,P61088,O15111,Q02750,Q16539,Q13616,P09429
Processes and pathways
Reactome Pathways
msigdb_reactome
430,182,294,652,675,574,437,257
652,257,1475,666,182,865,294,430,675,1429,437,1436,1488,1867,574,2099
0.794898196074666,1.2640374297013774,0.17269137095443782,0.794898196074666,1.4033026844567509,0.6526028648357912,1.2174684580139272,1.030438131327194,0.794898196074666,0.22108637922276436,1.030438131327194,0.22108637922276436,0.17269137095443782,-0.1687481002224421,0.8893530432986828,-0.366054672771204
3,216
Interleukin 17 signaling
8
14
2.676128
0.007448
P63208,P30154,P61088,O15111,Q02750,Q16539,Q13616,P30153
Processes and pathways
Reactome Pathways
msigdb_reactome
430,182,294,652,675,574,437,666
652,1475,666,182,865,294,430,675,1429,437,1436,1488,1867,574
0.794898196074666,0.17269137095443782,0.794898196074666,1.4033026844567509,0.6526028648357912,1.2174684580139272,1.030438131327194,0.794898196074666,0.22108637922276436,1.030438131327194,0.22108637922276436,0.17269137095443782,-0.1687481002224421,0.8893530432986828
3,216
Positive regulation of erk1 and erk2 cascade
9
16
2.675708
0.007457
Q02952,Q06124,Q96AC1,P12931,P18615,P14174,P09429,P30046,P46109
Processes and pathways
GO Biological process
msigdb_gobp
431,676,233,283,43,349,257,205,58
977,1911,257,283,349,43,205,1565,2360,58,675,431,676,233,2914,1743
0.5573209122218296,-0.2179206085639643,1.2640374297013774,1.2174684580139272,1.124105593246472,1.9540430888750042,1.3569538751932833,0.07562021229046627,-0.6650560527011644,1.8629293399977658,0.794898196074666,1.030438131327194,0.794898196074666,1.3105323443353172,-1.324744331610297,-0.021832892459727565
3,216
Extrinsic apoptotic signaling pathway
19
40
2.666816
0.007657
Q92974,P42575,P21359,Q99497,P38398,P12931,P61289,O95817,Q12933,P26583,Q99504,P48506,P30153,Q07820,P30154,Q9NVQ4,Q9UNN5,Q9NR09,Q86WB0
Processes and pathways
GO Biological process
msigdb_gobp
686,21,25,301,508,283,177,174,434,424,52,669,666,189,182,487,491,644,525
1900,977,174,2834,1809,1251,283,25,424,3064,666,182,721,1917,508,21,994,669,1139,1369,1199,177,1643,189,2994,434,875,1710,1081,525,3144,686,301,52,2144,644,487,1547,1178,491
-0.2179206085639643,0.5573209122218296,1.4495794234747916,-1.2222396128348902,-0.11967676552251524,0.36572137390740567,1.2174684580139272,2.1806988872910344,1.030438131327194,-1.6862890512220343,0.794898196074666,1.4033026844567509,0.7475489758869491,-0.2179206085639643,0.9364602576476364,2.2709206091816405,0.5573209122218296,0.794898196074666,0.4616961579572844,0.2693890486299308,0.41375298229412827,1.4495794234747916,0.02694194594229031,1.4033026844567509,-1.4791685400274208,1.030438131327194,0.6526028648357912,-0.021832892459727565,0.5095518305985256,0.9364602576476364,-1.9471045239939413,0.794898196074666,1.2174684580139272,1.9085189906980928,-0.4156376825645661,0.842165951616307,0.9834883672939752,0.12420299769392679,0.4616961579572844,0.9834883672939752
3,216
Perinuclear region of cytoplasm
63
178
2.662476
0.007757
Q9Y5X3,Q15437,Q96A49,P58546,Q7L5N1,P26038,Q9H6S0,Q9H223,Q9UL15,Q9UBF8,Q9BZE9,Q99497,Q9UII4,Q16513,Q92597,P22681,Q92905,O14976,O75340,P12931,Q13614,Q5T447,Q9Y224,P26583,O00299,P31946,Q92530,Q8NC51,Q27J81,P30041,Q13492,Q13177,Q9H2J4,Q15642,Q15436,P39687,Q9H4M9,Q14240,P17655,Q9UNN5,Q9UN37,Q99627,O15027,P27695,Q96QK1,Q9UI30,O75935,Q9BZG1,Q9UNS2,Q9UPY3,P15311,P84085,Q9UBB4,P11142,Q07960,O60645,O43709,O75592,O60271,O00429,O60566,P46821,P49593
Localization
GO Cellular component
msigdb_gocc
544,6,402,388,809,504,825,693,171,169,167,301,833,806,579,285,447,775,654,283,44,190,199,424,546,183,751,749,67,314,208,875,756,881,879,563,757,876,204,491,905,639,82,464,638,107,460,641,245,246,714,99,646,712,873,459,601,845,844,703,602,356,357
546,703,1407,1352,775,82,1685,1844,601,1054,2670,844,602,459,1354,654,1957,845,1409,460,1188,1625,1412,2756,2501,2070,1414,2502,915,2210,1302,2117,1962,1059,2402,1809,1251,712,1470,1510,283,2716,714,2262,1132,204,1851,922,1963,1363,285,2211,1253,504,424,464,2895,314,1420,2631,1256,183,1307,2408,2552,563,856,2312,994,1197,1634,356,357,3012,1069,1479,2026,1201,2939,388,1920,1641,1203,3013,1262,99,1150,2416,2168,1768,873,1011,1924,1583,2994,875,1821,208,44,876,2424,1272,1487,2130,879,6,1984,881,806,67,190,1871,1160,2692,1778,809,1659,1090,2178,2884,1601,2969,2737,749,1445,1492,751,579,447,2435,2281,402,1166,2236,638,1448,301,1998,639,1170,2187,2854,167,641,2190,1674,693,2290,1172,756,1173,757,825,1288,1453,2950,1613,2662,646,169,1230,107,833,2447,171,1896,905,1617,491,245,246,1619,199,2619,1743,1349,544,1236
0.8893530432986828,0.7475489758869491,0.22108637922276436,0.2693890486299308,0.7001174756266921,1.7257615558657298,-0.021832892459727565,-0.1687481002224421,0.842165951616307,0.5095518305985256,-1.0183189340779024,0.6526028648357912,0.842165951616307,0.9834883672939752,0.2693890486299308,0.794898196074666,-0.2671955040084828,0.6526028648357912,0.22108637922276436,0.9834883672939752,0.41375298229412827,0.02694194594229031,0.22108637922276436,-1.1200961902344955,-0.8158831663999228,-0.366054672771204,0.22108637922276436,-0.8158831663999228,0.6050042976186534,-0.5151066365455765,0.3176003848945597,-0.4156376825645661,-0.2671955040084828,0.5095518305985256,-0.7152351825377116,-0.11967676552251524,0.36572137390740567,0.7475489758869491,0.17269137095443782,0.12420299769392679,1.2174684580139272,-1.0691614811317376,0.7475489758869491,-0.5649910544332091,0.4616961579572844,1.3569538751932833,-0.1687481002224421,0.6050042976186534,-0.2671955040084828,0.2693890486299308,1.2174684580139272,-0.5151066365455765,0.36572137390740567,0.9364602576476364,1.030438131327194,0.9834883672939752,-1.324744331610297,1.1708247446272457,0.22108637922276436,-0.9675691815600861,0.36572137390740567,1.4033026844567509,0.3176003848945597,-0.7152351825377116,-0.8663506399354521,0.8893530432986828,0.6526028648357912,-0.6149744369312105,0.5573209122218296,0.41375298229412827,0.02694194594229031,1.124105593246472,1.124105593246472,-1.5308188918515426,0.5095518305985256,0.17269137095443782,-0.3165736808932445,0.41375298229412827,-1.3761306947603842,1.077310295637479,-0.2179206085639643,0.02694194594229031,0.41375298229412827,-1.5308188918515426,0.36572137390740567,1.6799041353764064,0.4616961579572844,-0.7152351825377116,-0.4653219270618636,-0.07070541701478243,0.6526028648357912,0.5573209122218296,-0.2179206085639643,0.07562021229046627,-1.4791685400274208,0.6526028648357912,-0.11967676552251524,1.3569538751932833,1.9540430888750042,0.6526028648357912,-0.7152351825377116,0.36572137390740567,0.17269137095443782,-0.4156376825645661,0.6526028648357912,3.2917003609170967,-0.2671955040084828,0.6526028648357912,0.7001174756266921,1.8172735893082128,1.4033026844567509,-0.1687481002224421,0.4616961579572844,-1.0183189340779024,-0.07070541701478243,0.7001174756266921,0.02694194594229031,0.5095518305985256,-0.4653219270618636,-1.2734471088745247,0.07562021229046627,-1.4276056206522965,-1.0691614811317376,0.7475489758869491,0.22108637922276436,0.17269137095443782,0.7475489758869491,0.8893530432986828,1.030438131327194,-0.7152351825377116,-0.5649910544332091,1.077310295637479,0.4616961579572844,-0.5151066365455765,0.842165951616307,0.22108637922276436,1.2174684580139272,-0.2671955040084828,0.842165951616307,0.4616961579572844,-0.4653219270618636,-1.2222396128348902,1.4957847330195655,0.842165951616307,-0.4653219270618636,0.02694194594229031,0.794898196074666,-0.5649910544332091,0.4616961579572844,0.7475489758869491,0.4616961579572844,0.7475489758869491,0.7001174756266921,0.36572137390740567,0.22108637922276436,-1.3761306947603842,0.07562021229046627,-0.9675691815600861,0.842165951616307,1.4957847330195655,0.41375298229412827,1.6799041353764064,0.7001174756266921,-0.7152351825377116,1.4957847330195655,-0.1687481002224421,0.6526028648357912,0.07562021229046627,0.9834883672939752,1.3105323443353172,1.3105323443353172,0.07562021229046627,1.4033026844567509,-0.9169128659873441,-0.021832892459727565,0.3176003848945597,0.9364602576476364,0.41375298229412827
3,216
Macrocytic anemia
18
34
2.649052
0.008072
Q99707,Q7Z2Z2,P00492,P42766,P22314,P08708,P62847,P62244,P62899,Q5F1R6,O00429,P11172,Q9Y3A5,O43175,P62854,P11586,P62081,P61011
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
273,522,553,36,663,554,9,1004,50,950,703,917,769,600,266,1060,59,799
703,600,2623,553,554,917,1060,2799,663,2122,36,1421,1635,1480,799,2511,1075,59,1004,1705,1523,9,266,1428,50,1861,1708,950,2042,522,273,1291,769,1294
0.7475489758869491,0.842165951616307,-0.9675691815600861,0.8893530432986828,0.8893530432986828,0.6050042976186534,0.5095518305985256,-1.1711224385842194,0.794898196074666,-0.4156376825645661,2.0448967765740447,0.22108637922276436,0.02694194594229031,0.17269137095443782,0.7001174756266921,-0.8158831663999228,0.5095518305985256,1.8629293399977658,0.5573209122218296,-0.021832892459727565,0.12420299769392679,2.8515348159764975,1.2640374297013774,0.22108637922276436,1.9085189906980928,-0.1687481002224421,-0.021832892459727565,0.6050042976186534,-0.3165736808932445,0.9364602576476364,1.2640374297013774,0.36572137390740567,0.7475489758869491,0.36572137390740567
3,216
Phosphatidylinositol phosphate biosynthetic process
6
12
2.639353
0.008306
O95861,Q92551,O00443,Q8TBX8,P29218,Q9UBF8
Processes and pathways
GO Biological process
msigdb_gobp
497,14,382,890,665,169
382,497,665,1703,1578,1651,890,14,1884,898,1225,169
1.077310295637479,0.9364602576476364,0.794898196074666,-0.021832892459727565,0.07562021229046627,0.02694194594229031,0.6526028648357912,2.49540773157476,-0.1687481002224421,0.6526028648357912,0.41375298229412827,1.4957847330195655
3,216
Secondary metabolic process
6
12
2.634451
0.008427
O14908,Q8N4T8,Q9Y5N5,O43488,Q9UKG1,P30046
Processes and pathways
GO Biological process
msigdb_gobp
457,361,215,309,79,205
457,309,845,1061,1131,205,509,361,2057,79,1743,215
0.9834883672939752,1.1708247446272457,0.6526028648357912,0.5095518305985256,0.4616961579572844,1.3569538751932833,0.9364602576476364,1.124105593246472,-0.3165736808932445,1.7715511827549129,-0.021832892459727565,1.3569538751932833
3,216
Telomere c strand lagging strand synthesis
11
23
2.627169
0.00861
Q15054,P39748,Q8WVB6,P27694,P35244,P40937,P09884,P12004,P49643,P49642,P35250
Processes and pathways
Reactome Pathways
msigdb_reactome
805,184,750,463,39,427,282,500,290,671,425
282,500,1252,1630,463,792,39,1194,425,1813,184,427,1702,1368,671,290,1763,1484,805,2689,750,1041,2496
1.2174684580139272,0.9364602576476364,0.36572137390740567,0.02694194594229031,0.9834883672939752,0.7001174756266921,1.9995021737690988,0.41375298229412827,1.030438131327194,-0.11967676552251524,1.4033026844567509,1.030438131327194,-0.021832892459727565,0.2693890486299308,0.794898196074666,1.2174684580139272,-0.07070541701478243,0.17269137095443782,0.7001174756266921,-1.0183189340779024,0.7475489758869491,0.5573209122218296,-0.7655111190576772
3,216
Ficolin 1 rich granule
51
92
2.621386
0.008757
P51665,Q9UJU6,Q13200,Q9UNM6,P04075,P06744,Q96G03,O00232,P09429,Q9NZ32,Q9P000,Q99436,Q9Y6G9,P25787,Q16539,Q9Y315,O75874,Q08554,P12268,P15924,P20618,P12956,P68402,P35998,O14727,O43242,O00487,Q9UBI1,Q7Z6Z7,P13639,P13798,O95352,P04080,P53618,P50990,Q15008,P61160,Q86VP6,O60610,P17858,P20839,P17980,P28066,P11142,P35237,P09972,P14174,P36871,P09960,P18669,O00231
Localization
GO Cellular component
msigdb_gocc
725,541,622,412,498,499,688,248,257,697,27,958,701,156,574,179,655,943,660,785,786,918,801,667,55,548,773,341,747,556,558,310,312,567,565,877,319,1025,458,715,717,716,465,712,852,348,349,354,603,605,838
838,248,773,1900,55,548,458,655,1692,310,1355,498,312,1127,499,1301,2210,1302,2459,1059,257,603,348,1251,2305,712,1470,660,918,556,558,349,1130,1562,2798,785,2262,715,716,1628,605,786,717,1852,156,465,1475,852,1632,667,354,1566,3104,565,725,1071,567,1201,319,1574,1576,1646,2082,1318,1972,801,943,1925,2558,622,2685,1431,1016,877,574,1328,2561,1828,747,1025,2281,688,958,2747,697,27,341,541,412,1948,179,701
0.6526028648357912,1.2640374297013774,0.7001174756266921,-0.2179206085639643,1.8629293399977658,0.8893530432986828,0.9834883672939752,0.794898196074666,-0.021832892459727565,1.1708247446272457,0.2693890486299308,0.9364602576476364,1.1708247446272457,0.4616961579572844,0.9364602576476364,0.3176003848945597,-0.5151066365455765,0.3176003848945597,-0.7655111190576772,0.5095518305985256,1.2640374297013774,0.842165951616307,1.124105593246472,0.36572137390740567,-0.6149744369312105,0.7475489758869491,0.17269137095443782,0.794898196074666,0.6050042976186534,0.8893530432986828,0.8893530432986828,1.124105593246472,0.4616961579572844,0.07562021229046627,-1.1711224385842194,0.7001174756266921,-0.5649910544332091,0.7475489758869491,0.7475489758869491,0.02694194594229031,0.842165951616307,0.7001174756266921,0.7475489758869491,-0.1687481002224421,1.4957847330195655,0.9834883672939752,0.17269137095443782,0.6526028648357912,0.02694194594229031,0.794898196074666,1.124105593246472,0.07562021229046627,-1.7903630545253904,0.8893530432986828,0.7475489758869491,0.5095518305985256,0.8893530432986828,0.41375298229412827,1.1708247446272457,0.07562021229046627,0.07562021229046627,0.02694194594229031,-0.366054672771204,0.3176003848945597,-0.2671955040084828,0.7001174756266921,0.6050042976186534,-0.2179206085639643,-0.8663506399354521,0.842165951616307,-1.0183189340779024,0.22108637922276436,0.5573209122218296,0.6526028648357912,0.8893530432986828,0.3176003848945597,-0.8663506399354521,-0.11967676552251524,0.7475489758869491,0.5573209122218296,-0.5649910544332091,0.794898196074666,0.6050042976186534,-1.0691614811317376,0.794898196074666,2.1806988872910344,1.1708247446272457,0.9364602576476364,1.077310295637479,-0.2179206085639643,1.4495794234747916,0.794898196074666
3,216
Threonine type peptidase activity
8
9
2.614013
0.008949
P25789,P28074,P49721,P28070,Q7L266,P20618,P49720,Q99436
Functions
GO Molecular function
msigdb_gomf
181,791,187,506,471,786,358,958
786,181,506,925,791,358,187,471,958
0.7001174756266921,1.4033026844567509,0.9364602576476364,0.6050042976186534,0.7001174756266921,1.124105593246472,1.4033026844567509,0.9834883672939752,0.6050042976186534
3,216
Anion transmembrane transport
14
37
3.511708
0.000445
P45880,Q9H2D1,P21796,Q8TB61,Q9UBX3,Q13546,P53007,O43808,Q96NB2,Q9UHG3,Q15758,Q9H9B4,Q00325,Q9Y277
Processes and pathways
GO Biological process
msigdb_gobp
66,1,65,341,236,99,326,96,113,20,373,296,330,272
96,1338,359,2748,988,654,2586,1644,1070,584,65,1650,66,326,2704,2758,330,757,99,1776,373,1587,2722,341,1024,113,499,1,296,2174,1616,236,20,883,272,1326,890
1.6756866487455853,0.15633251874022483,0.9185169053570901,-0.854852845001873,0.38007859388666043,0.598934426926407,-0.6687843869463775,-0.014824683336963967,0.32460928917017773,0.6529098806119115,1.9633274991781329,-0.014824683336963967,1.9633274991781329,0.9708057586304926,-0.7924421870337799,-0.854852845001873,0.9708057586304926,0.5446668824908113,1.6756866487455853,-0.07253494183063504,0.9185169053570901,0.04255405207435462,-0.7924421870337799,0.9708057586304926,0.38007859388666043,1.62694013996398,0.7599973733245824,6.1027541191014,1.0745745880220183,-0.3067719053974511,0.04255405207435462,1.1772838549439275,3.697105660578045,0.4901039644802168,1.1260602689980173,0.21273986061826164,0.4901039644802168
3,216
Respirasome
17
37
3.38444
0.000713
Q9Y276,Q9UDW1,Q96CU9,O75380,Q6DKK2,Q16795,O00483,O75306,O95182,P13073,O43678,P47985,P49821,Q13423,P08574,O75489,O43674
Localization
GO Cellular component
msigdb_gocc
238,107,450,70,618,72,241,162,522,219,21,125,325,25,478,398,57
241,57,21,815,162,70,398,580,522,1439,1443,1161,478,1343,219,1345,659,1072,1746,1173,1549,1651,1079,125,325,836,25,3084,72,1977,618,2330,450,1048,107,238,2516
1.1260602689980173,2.104137155032703,3.4551147492200505,0.4901039644802168,1.3294092295054736,1.9159521152124348,0.8659545453435412,0.6529098806119115,0.7065964713851883,0.09960517303232037,0.09960517303232037,0.26883090389803893,0.7599973733245824,0.15633251874022483,1.1772838549439275,0.15633251874022483,0.598934426926407,0.32460928917017773,-0.07253494183063504,0.26883090389803893,0.04255405207435462,-0.014824683336963967,0.32460928917017773,1.5287351424822555,0.9708057586304926,0.4901039644802168,3.2072507817126157,-1.6361198796349998,1.9159521152124348,-0.18896601992068227,0.6529098806119115,-0.4259865462215386,0.8131157079420699,0.38007859388666043,1.6756866487455853,1.1772838549439275,-0.546645177342604
3,216
SLC superfamily of solute carriers
13
34
3.207432
0.001339
Q9H2D1,Q9UBX3,Q8TB61,O43772,Q70HW3,P53007,O43808,Q9Y6C9,Q96NB2,Q15758,Q9NZJ7,Q9H9B4,Q00325
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
1,236,341,5,7,326,96,78,113,373,124,296,330
5,96,359,1250,988,654,1644,1070,584,1650,326,2704,2758,330,757,373,619,1381,7,2722,341,113,3207,786,499,1,2001,296,2174,124,236,883,78,890
5.247861600040695,1.6756866487455853,0.9185169053570901,0.21273986061826164,0.38007859388666043,0.598934426926407,-0.014824683336963967,0.32460928917017773,0.6529098806119115,-0.014824683336963967,0.9708057586304926,-0.7924421870337799,-0.854852845001873,0.9708057586304926,0.5446668824908113,0.9185169053570901,0.6529098806119115,0.15633251874022483,5.213527788933368,-0.7924421870337799,0.9708057586304926,1.62694013996398,-4.621457222623344,0.5446668824908113,0.7599973733245824,6.1027541191014,-0.18896601992068227,1.0745745880220183,-0.3067719053974511,1.5779570986245492,1.1772838549439275,0.4901039644802168,1.868353764466578,0.4901039644802168
3,216
Atp synthesis coupled electron transport
15
33
3.041104
0.002357
Q9UDW1,O75380,Q16795,P13073,O75306,O00483,O95182,O95168,P14635,O43678,P47985,P49821,O43674,P08574,O75489
Processes and pathways
GO Biological process
msigdb_gobp
107,70,72,219,162,241,522,580,140,21,125,325,57,478,398
241,57,21,815,162,70,398,580,522,1439,1443,1161,907,478,1645,1343,219,140,659,1072,1549,1651,125,325,836,3084,72,1977,1216,2416,2002,107,2516
1.1260602689980173,2.104137155032703,3.4551147492200505,0.4901039644802168,1.3294092295054736,1.9159521152124348,0.8659545453435412,0.6529098806119115,0.7065964713851883,0.09960517303232037,0.09960517303232037,0.26883090389803893,0.4352423338200509,0.7599973733245824,-0.014824683336963967,0.15633251874022483,1.1772838549439275,1.4295647732720183,0.598934426926407,0.32460928917017773,0.04255405207435462,-0.014824683336963967,1.5287351424822555,0.9708057586304926,0.4901039644802168,-1.6361198796349998,1.9159521152124348,-0.18896601992068227,0.26883090389803893,-0.48613310875494586,-0.18896601992068227,1.6756866487455853,-0.546645177342604
3,216
Biological oxidations
23
49
3.014386
0.002575
P48507,P05091,O00170,O43488,Q5VT66,P07099,Q96IU4,O43169,P30837,Q9NUJ1,Q16850,Q99735,Q969Z3,P78417,P21964,P21266,Q8TB61,P00387,P16435,O60701,P28161,O43708,O95861
Processes and pathways
Reactome Pathways
msigdb_reactome
596,247,240,242,549,13,158,27,34,40,284,453,314,182,175,427,341,198,586,469,590,467,582
240,1820,27,1244,242,467,469,2441,1252,582,198,247,13,2448,2522,1344,913,586,427,175,915,1842,590,34,2595,1847,596,1083,182,1968,284,2321,549,341,702,314,864,158,1405,1994,453,2001,1888,797,40,1812,882,1056,1239
1.1260602689980173,-0.13058070315460985,2.953211606238473,0.21273986061826164,1.1260602689980173,0.7599973733245824,0.7599973733245824,-0.546645177342604,0.21273986061826164,0.6529098806119115,1.2282480860545921,1.1260602689980173,4.42772984322683,-0.546645177342604,-0.6075273683129577,0.15633251874022483,0.4352423338200509,0.6529098806119115,0.8131157079420699,1.2789556593345546,0.4352423338200509,-0.13058070315460985,0.6529098806119115,2.6926708657040783,-0.6687843869463775,-0.13058070315460985,0.6529098806119115,0.32460928917017773,1.2789556593345546,-0.18896601992068227,1.0745745880220183,-0.4259865462215386,0.7065964713851883,0.9708057586304926,0.598934426926407,1.0228240276985572,0.4901039644802168,1.3796114098899142,0.15633251874022483,-0.18896601992068227,0.8131157079420699,-0.18896601992068227,-0.13058070315460985,0.5446668824908113,2.559853153319494,-0.07253494183063504,0.4901039644802168,0.38007859388666043,0.26883090389803893
3,216
Primary active transmembrane transporter activity
17
43
2.942419
0.003257
P06576,Q9UDW1,O75380,Q16795,P13073,O75306,O00483,O95182,P23634,Q9HD20,O43678,P47985,P61421,P49821,O43674,P08574,O75489
Functions
GO Molecular function
msigdb_gomf
477,107,70,72,219,162,241,522,46,51,21,125,535,325,57,478,398
241,57,21,1731,815,162,70,398,580,522,1439,1443,1161,1835,734,477,478,1343,219,1345,1259,659,1931,1072,1348,1545,46,1175,1549,1079,2873,1455,125,325,836,535,3084,72,51,1889,107,1714,2516
1.1260602689980173,2.104137155032703,3.4551147492200505,-0.07253494183063504,0.4901039644802168,1.3294092295054736,1.9159521152124348,0.8659545453435412,0.6529098806119115,0.7065964713851883,0.09960517303232037,0.09960517303232037,0.26883090389803893,-0.13058070315460985,0.5446668824908113,0.7599973733245824,0.7599973733245824,0.15633251874022483,1.1772838549439275,0.15633251874022483,0.21273986061826164,0.598934426926407,-0.18896601992068227,0.32460928917017773,0.15633251874022483,0.04255405207435462,2.3345548914896983,0.26883090389803893,0.04255405207435462,0.32460928917017773,-1.0444731823352504,0.09960517303232037,1.5287351424822555,0.9708057586304926,0.4901039644802168,0.7065964713851883,-1.6361198796349998,1.9159521152124348,2.1969339488404867,-0.13058070315460985,1.6756866487455853,-0.014824683336963967,-0.546645177342604
3,216
Mitochondrial transmembrane transport
24
44
2.941467
0.003267
Q9H2D1,O43772,Q6P4A7,Q3ZCQ8,O60830,Q9H9B4,P05141,P24539,O75964,P56134,O95831,O96008,P21796,Q8TAA5,P23786,Q8NE86,P53007,Q00325,Q9Y4W6,P12236,Q96NB2,Q9UJZ1,O75746,P06576
Processes and pathways
GO Biological process
msigdb_gobp
1,5,699,253,24,296,654,527,54,533,58,652,65,340,76,339,326,330,642,584,113,391,359,477
1060,983,5,24,1731,1063,359,818,54,1639,1250,988,58,652,654,477,2450,1070,584,65,76,527,1934,3025,671,3115,326,533,330,253,699,2722,339,340,2406,1211,113,955,1,296,2731,883,391,642
0.32460928917017773,0.38007859388666043,5.247861600040695,3.2489818306311413,-0.07253494183063504,0.32460928917017773,0.9185169053570901,0.4901039644802168,2.1506418231566373,-0.014824683336963967,0.21273986061826164,0.38007859388666043,2.104137155032703,0.598934426926407,0.598934426926407,0.7599973733245824,-0.546645177342604,0.32460928917017773,0.6529098806119115,1.9633274991781329,1.868353764466578,0.7065964713851883,-0.18896601992068227,-1.3687923128782735,0.598934426926407,-1.8414697677680782,0.9708057586304926,0.7065964713851883,0.9708057586304926,1.1260602689980173,0.598934426926407,-0.7924421870337799,0.9708057586304926,0.9708057586304926,-0.48613310875494586,0.26883090389803893,1.62694013996398,0.4352423338200509,6.1027541191014,1.0745745880220183,-0.7924421870337799,0.4901039644802168,0.9185169053570901,0.6529098806119115
3,216
Electron transport
17
41
2.880106
0.003975
Q9H3N1,Q9UDW1,Q96CU9,O75380,Q6DKK2,Q16795,O00483,O75306,O95182,O43678,P47985,P49821,O43674,O43169,P08574,O75489,O95864
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
170,107,450,70,618,72,241,162,522,21,125,325,57,27,478,398,423
241,27,812,57,21,815,162,70,398,580,522,1439,423,1443,1161,478,994,659,1746,915,1173,1549,1651,1079,2213,125,325,836,936,3084,72,1376,618,2330,450,1304,2173,170,1048,107,2516
1.1260602689980173,2.953211606238473,0.4901039644802168,2.104137155032703,3.4551147492200505,0.4901039644802168,1.3294092295054736,1.9159521152124348,0.8659545453435412,0.6529098806119115,0.7065964713851883,0.09960517303232037,0.8131157079420699,0.09960517303232037,0.26883090389803893,0.7599973733245824,0.38007859388666043,0.598934426926407,-0.07253494183063504,0.4352423338200509,0.26883090389803893,0.04255405207435462,-0.014824683336963967,0.32460928917017773,-0.36620096012652253,1.5287351424822555,0.9708057586304926,0.4901039644802168,0.4352423338200509,-1.6361198796349998,1.9159521152124348,0.15633251874022483,0.6529098806119115,-0.4259865462215386,0.8131157079420699,0.21273986061826164,-0.3067719053974511,1.3294092295054736,0.38007859388666043,1.6756866487455853,-0.546645177342604
3,216
Electron transport chain oxphos system in mitochondria
21
42
2.74998
0.00596
P06576,O00483,O43678,O75489,O75306,P05141,O95182,P19404,P24539,O75964,P56134,O43674,O75380,Q16795,P49821,Q9UDW1,P13073,P12236,O95168,O75880,P47985
Processes and pathways
WikiPathways
msigdb_wp
477,241,21,398,162,654,522,659,527,54,533,57,70,72,325,107,219,584,580,470,125
241,57,21,815,162,70,398,470,818,54,580,522,1439,1443,1161,654,477,1343,1070,584,219,1345,659,1072,1746,1173,527,1934,1549,1651,1079,3025,125,671,325,836,533,3084,72,107,2516,2691
1.1260602689980173,2.104137155032703,3.4551147492200505,0.4901039644802168,1.3294092295054736,1.9159521152124348,0.8659545453435412,0.7599973733245824,0.4901039644802168,2.1506418231566373,0.6529098806119115,0.7065964713851883,0.09960517303232037,0.09960517303232037,0.26883090389803893,0.598934426926407,0.7599973733245824,0.15633251874022483,0.32460928917017773,0.6529098806119115,1.1772838549439275,0.15633251874022483,0.598934426926407,0.32460928917017773,-0.07253494183063504,0.26883090389803893,0.7065964713851883,-0.18896601992068227,0.04255405207435462,-0.014824683336963967,0.32460928917017773,-1.3687923128782735,1.5287351424822555,0.598934426926407,0.9708057586304926,0.4901039644802168,0.7065964713851883,-1.6361198796349998,1.9159521152124348,1.6756866487455853,-0.546645177342604,-0.7304210297875838
3,216
Ragged red muscle fibers
6
18
2.622326
0.008733
Q9Y276,Q9H2D1,Q70HW3,P54098,O75648,O95831
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
238,1,7,47,109,58
1912,109,58,1161,1070,1651,1269,47,2139,1482,7,2556,1501,787,1,1806,300,238
-0.18896601992068227,1.62694013996398,2.104137155032703,0.26883090389803893,0.32460928917017773,-0.014824683336963967,0.21273986061826164,2.3345548914896983,-0.3067719053974511,0.09960517303232037,5.213527788933368,-0.6075273683129577,0.09960517303232037,0.5446668824908113,6.1027541191014,-0.07253494183063504,1.0745745880220183,1.1772838549439275
3,216
Intrinsic component of mitochondrial membrane
21
41
2.574411
0.010041
Q8IXI2,Q6P4A7,Q9BUR5,Q9H9B4,Q13505,O60830,P50336,Q8IWA4,Q53H12,O43819,O96008,Q16891,Q8NE86,Q00325,Q9Y4W6,Q9NVH1,Q8TB36,Q6UXV4,Q96NB2,O75880,Q9UH62
Localization
GO Cellular component
msigdb_gocc
552,699,159,296,26,24,279,442,440,173,652,615,339,330,642,507,104,376,113,470,798
1060,173,24,731,470,1639,1640,988,652,1070,2599,279,3115,330,26,936,615,440,2483,699,376,442,1116,552,339,104,113,955,159,2089,2002,296,2174,1889,507,1710,1142,798,642,976,2691
0.32460928917017773,1.2789556593345546,3.2489818306311413,0.5446668824908113,0.7599973733245824,-0.014824683336963967,-0.014824683336963967,0.38007859388666043,0.598934426926407,0.32460928917017773,-0.6687843869463775,1.0745745880220183,-1.8414697677680782,0.9708057586304926,3.2072507817126157,0.4352423338200509,0.6529098806119115,0.8131157079420699,-0.546645177342604,0.598934426926407,0.9185169053570901,0.8131157079420699,0.32460928917017773,0.7065964713851883,0.9708057586304926,1.6756866487455853,1.62694013996398,0.4352423338200509,1.3796114098899142,-0.24769501940385638,-0.18896601992068227,1.0745745880220183,-0.3067719053974511,-0.13058070315460985,0.7599973733245824,-0.014824683336963967,0.32460928917017773,0.5446668824908113,0.6529098806119115,0.4352423338200509,-0.7304210297875838
3,216
Carbohydrate derivative catabolic process
9
37
2.550516
0.010756
P54802,Q9BTY2,P33908,Q9NUJ1,Q9H773,Q9Y315,Q13126,O60502,Q9UJ70
Processes and pathways
GO Biological process
msigdb_gobp
179,169,130,40,211,115,15,17,237
1526,17,653,1162,1066,1165,655,2026,1447,1171,249,2751,1546,3114,130,593,3129,1561,2217,832,179,1275,2976,15,2157,2492,863,953,169,2268,1510,211,565,40,237,115,2013
0.04255405207435462,3.8944812172553123,0.598934426926407,0.26883090389803893,0.32460928917017773,0.26883090389803893,0.598934426926407,-0.24769501940385638,0.09960517303232037,0.26883090389803893,1.1260602689980173,-0.854852845001873,0.04255405207435462,-1.8414697677680782,1.4792718527358455,0.6529098806119115,-1.9807820245726757,0.04255405207435462,-0.36620096012652253,0.4901039644802168,1.2789556593345546,0.21273986061826164,-1.2377883135314274,4.126418509720479,-0.3067719053974511,-0.546645177342604,0.4901039644802168,0.4352423338200509,1.3294092295054736,-0.36620096012652253,0.09960517303232037,1.2282480860545921,0.7065964713851883,2.559853153319494,1.1772838549439275,1.62694013996398,-0.18896601992068227
3,216
Parkinsons disease
22
49
2.548082
0.010832
P06576,O00483,O43678,O75489,O75306,P05141,O95182,P19404,P24539,O43674,P45880,P21796,O75380,Q16795,P49821,Q9UDW1,P13073,P12236,O95168,Q9Y277,P08574,P47985
Processes and pathways
KEGG Pathways
msigdb_kegg
477,241,21,398,162,654,522,659,527,57,66,65,70,72,325,107,219,584,580,272,478,125
241,1151,57,21,815,162,70,398,818,580,522,1439,1443,1161,654,477,478,1343,1070,584,219,1345,659,1072,65,1746,1932,1173,527,1934,1549,1651,1079,3025,1356,66,125,671,325,836,1762,928,1960,3084,72,1216,107,272,2516
1.1260602689980173,0.26883090389803893,2.104137155032703,3.4551147492200505,0.4901039644802168,1.3294092295054736,1.9159521152124348,0.8659545453435412,0.4901039644802168,0.6529098806119115,0.7065964713851883,0.09960517303232037,0.09960517303232037,0.26883090389803893,0.598934426926407,0.7599973733245824,0.7599973733245824,0.15633251874022483,0.32460928917017773,0.6529098806119115,1.1772838549439275,0.15633251874022483,0.598934426926407,0.32460928917017773,1.9633274991781329,-0.07253494183063504,-0.18896601992068227,0.26883090389803893,0.7065964713851883,-0.18896601992068227,0.04255405207435462,-0.014824683336963967,0.32460928917017773,-1.3687923128782735,0.15633251874022483,1.9633274991781329,1.5287351424822555,0.598934426926407,0.9708057586304926,0.4901039644802168,-0.07253494183063504,0.4352423338200509,-0.18896601992068227,-1.6361198796349998,1.9159521152124348,0.26883090389803893,1.6756866487455853,1.1260602689980173,-0.546645177342604
3,216
Abnormal basal ganglia mri signal intensity
11
27
2.517091
0.011833
Q92947,Q16795,O00483,O75306,Q8NI60,Q4G0N4,P16278,Q86YH6,O43678,P49821,O75489
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
379,72,241,162,208,254,249,81,21,325,398
241,21,815,162,1912,398,1439,3020,249,659,1549,1078,1651,2042,325,1269,72,254,81,208,379,1303,450,1498,955,2565,2006
1.1260602689980173,3.4551147492200505,0.4901039644802168,1.3294092295054736,-0.18896601992068227,0.8659545453435412,0.09960517303232037,-1.3687923128782735,1.1260602689980173,0.598934426926407,0.04255405207435462,0.32460928917017773,-0.014824683336963967,-0.24769501940385638,0.9708057586304926,0.21273986061826164,1.9159521152124348,1.1260602689980173,1.8205302691917176,1.2282480860545921,0.9185169053570901,0.21273986061826164,0.8131157079420699,0.09960517303232037,0.4352423338200509,-0.6075273683129577,-0.18896601992068227
3,216
Oxidative phosphorylation
22
51
2.496625
0.012538
P06576,O00483,Q9H2U2,O43678,O75489,Q15904,O75306,O95182,P24539,P61421,O75964,P56134,O43674,O75380,Q16795,Q93050,P49821,Q9UDW1,P13073,Q15181,P08574,P47985
Processes and pathways
KEGG Pathways
msigdb_kegg
477,241,562,21,398,164,162,522,527,535,54,533,57,70,72,83,325,107,219,372,478,125
241,57,21,815,162,70,398,818,54,580,522,1439,1443,1161,477,478,1343,219,1345,659,1072,1348,1545,1746,1173,527,1934,1549,1651,1079,3025,2873,1455,125,671,325,836,533,535,372,164,3084,72,2330,83,562,107,1714,2100,2516,2691
1.1260602689980173,2.104137155032703,3.4551147492200505,0.4901039644802168,1.3294092295054736,1.9159521152124348,0.8659545453435412,0.4901039644802168,2.1506418231566373,0.6529098806119115,0.7065964713851883,0.09960517303232037,0.09960517303232037,0.26883090389803893,0.7599973733245824,0.7599973733245824,0.15633251874022483,1.1772838549439275,0.15633251874022483,0.598934426926407,0.32460928917017773,0.15633251874022483,0.04255405207435462,-0.07253494183063504,0.26883090389803893,0.7065964713851883,-0.18896601992068227,0.04255405207435462,-0.014824683336963967,0.32460928917017773,-1.3687923128782735,-1.0444731823352504,0.09960517303232037,1.5287351424822555,0.598934426926407,0.9708057586304926,0.4901039644802168,0.7065964713851883,0.7065964713851883,0.9185169053570901,1.3294092295054736,-1.6361198796349998,1.9159521152124348,-0.4259865462215386,1.8205302691917176,0.7065964713851883,1.6756866487455853,-0.014824683336963967,-0.24769501940385638,-0.546645177342604,-0.7304210297875838
3,216
Glycoprotein biosynthetic process
24
42
2.490365
0.012761
P39656,P33908,P04844,Q02809,O60502,Q9Y673,Q14165,O00469,Q10471,Q99805,P04843,O95394,O60762,Q96JB2,Q9H488,O14734,Q86SF2,Q9UHD1,Q9H4A6,Q2TAA5,Q86YN1,O60701,O43505,P35610
Processes and pathways
GO Biological process
msigdb_gobp
365,130,246,689,17,420,764,892,281,43,906,650,302,870,60,644,621,881,347,80,229,469,108,593
892,644,895,108,17,985,469,302,1912,986,650,906,246,130,1753,593,365,1657,2383,689,2139,2847,281,1374,764,80,1291,1489,621,229,2492,870,2674,43,3088,1806,60,347,1519,1712,881,420
0.4352423338200509,0.598934426926407,0.4352423338200509,1.62694013996398,3.8944812172553123,0.38007859388666043,0.7599973733245824,1.0228240276985572,-0.18896601992068227,0.38007859388666043,0.598934426926407,0.4352423338200509,1.1260602689980173,1.4792718527358455,-0.07253494183063504,0.6529098806119115,0.9185169053570901,-0.014824683336963967,-0.48613310875494586,0.598934426926407,-0.3067719053974511,-0.9808631043501542,1.0745745880220183,0.15633251874022483,0.5446668824908113,1.8205302691917176,0.21273986061826164,0.09960517303232037,0.6529098806119115,1.1772838549439275,-0.546645177342604,0.4901039644802168,-0.7304210297875838,2.425275325896919,-1.6361198796349998,-0.07253494183063504,2.104137155032703,0.9708057586304926,0.09960517303232037,-0.014824683336963967,0.4901039644802168,0.8659545453435412
3,216
Oxidoreductase activity acting on nad p h
14
28
2.464568
0.013718
O75380,Q16795,P16435,O75306,O00483,O95182,Q08257,O43678,P00387,P49821,Q13423,O95831,O75489,O43674
Functions
GO Molecular function
msigdb_gomf
70,72,586,162,241,522,77,21,198,325,25,58,398,57
241,57,21,815,162,70,398,580,522,1439,58,1443,198,2121,586,659,1549,325,836,77,25,3084,72,940,2721,970,1626,2516
1.1260602689980173,2.104137155032703,3.4551147492200505,0.4901039644802168,1.3294092295054736,1.9159521152124348,0.8659545453435412,0.6529098806119115,0.7065964713851883,0.09960517303232037,2.104137155032703,0.09960517303232037,1.2282480860545921,-0.3067719053974511,0.6529098806119115,0.598934426926407,0.04255405207435462,0.9708057586304926,0.4901039644802168,1.868353764466578,3.2072507817126157,-1.6361198796349998,1.9159521152124348,0.4352423338200509,-0.7924421870337799,0.4352423338200509,0.04255405207435462,-0.546645177342604
3,216
Inner mitochondrial membrane protein complex
31
65
2.461243
0.013846
P06576,O00483,Q3ZCQ8,O43678,Q9BUR5,O60830,Q13505,O75489,Q96CU9,O75306,O95182,P24539,O75964,P56134,O43674,Q53H12,Q8TAA5,O75380,Q16795,Q16891,Q8NE86,P49821,Q9Y4W6,Q9Y276,Q9NVH1,Q6UXV4,Q9UDW1,P13073,P12236,P08574,P47985
Localization
GO Cellular component
msigdb_gocc
477,241,253,21,159,24,26,398,450,162,522,527,54,533,57,440,340,70,72,615,339,325,642,238,507,376,107,219,584,478,125
241,1060,57,21,24,815,162,70,731,398,818,54,580,522,1439,1443,1161,477,478,1343,584,219,1345,659,1072,1746,1173,527,1934,1549,1651,1079,1553,3025,2599,125,671,325,836,533,26,3084,72,615,253,440,2483,376,2330,339,340,450,1497,1505,955,159,2731,507,1048,1710,107,238,642,976,2516
1.1260602689980173,0.32460928917017773,2.104137155032703,3.4551147492200505,3.2489818306311413,0.4901039644802168,1.3294092295054736,1.9159521152124348,0.5446668824908113,0.8659545453435412,0.4901039644802168,2.1506418231566373,0.6529098806119115,0.7065964713851883,0.09960517303232037,0.09960517303232037,0.26883090389803893,0.7599973733245824,0.7599973733245824,0.15633251874022483,0.6529098806119115,1.1772838549439275,0.15633251874022483,0.598934426926407,0.32460928917017773,-0.07253494183063504,0.26883090389803893,0.7065964713851883,-0.18896601992068227,0.04255405207435462,-0.014824683336963967,0.32460928917017773,0.04255405207435462,-1.3687923128782735,-0.6687843869463775,1.5287351424822555,0.598934426926407,0.9708057586304926,0.4901039644802168,0.7065964713851883,3.2072507817126157,-1.6361198796349998,1.9159521152124348,0.6529098806119115,1.1260602689980173,0.8131157079420699,-0.546645177342604,0.9185169053570901,-0.4259865462215386,0.9708057586304926,0.9708057586304926,0.8131157079420699,0.09960517303232037,0.09960517303232037,0.4352423338200509,1.3796114098899142,-0.7924421870337799,0.7599973733245824,0.38007859388666043,-0.014824683336963967,1.6756866487455853,1.1772838549439275,0.6529098806119115,0.4352423338200509,-0.546645177342604
3,216
Hormone metabolic process
9
28
2.43478
0.014901
Q8NBN7,Q99714,O75844,Q92506,P30536,Q6UWP2,Q53GQ0,Q9HB40,Q9Y394
Processes and pathways
GO Biological process
msigdb_gobp
103,381,75,260,19,375,156,88,239
730,75,1252,361,1835,735,2031,1448,586,19,2045,1183,1855,2886,156,1290,375,103,947,777,260,1304,381,88,1415,1713,1319,239
0.5446668824908113,1.868353764466578,0.21273986061826164,0.9185169053570901,-0.13058070315460985,0.5446668824908113,-0.24769501940385638,0.09960517303232037,0.6529098806119115,3.697105660578045,-0.24769501940385638,0.26883090389803893,-0.13058070315460985,-1.0444731823352504,1.3796114098899142,0.21273986061826164,0.9185169053570901,1.6756866487455853,0.4352423338200509,0.5446668824908113,1.1260602689980173,0.21273986061826164,0.9185169053570901,1.7724794192359936,0.15633251874022483,-0.014824683336963967,0.21273986061826164,1.1772838549439275
3,216
Intrinsic component of mitochondrial inner membrane
15
28
2.423096
0.015389
Q9NVH1,Q6UXV4,P50336,Q16891,Q96NB2,Q00325,O75880,Q8NE86,Q9BUR5,Q9H9B4,Q13505,Q53H12,Q9Y4W6,O60830,O43819
Localization
GO Cellular component
msigdb_gocc
507,376,279,615,113,330,470,339,159,296,26,440,642,24,173
1060,173,24,731,470,988,2599,279,330,26,936,615,440,2483,699,376,339,113,159,2002,296,2174,507,1710,1142,642,976,2691
0.32460928917017773,1.2789556593345546,3.2489818306311413,0.5446668824908113,0.7599973733245824,0.38007859388666043,-0.6687843869463775,1.0745745880220183,0.9708057586304926,3.2072507817126157,0.4352423338200509,0.6529098806119115,0.8131157079420699,-0.546645177342604,0.598934426926407,0.9185169053570901,0.9708057586304926,1.62694013996398,1.3796114098899142,-0.18896601992068227,1.0745745880220183,-0.3067719053974511,0.7599973733245824,-0.014824683336963967,0.32460928917017773,0.6529098806119115,0.4352423338200509,-0.7304210297875838
3,216
Proton transmembrane transport
18
38
2.416567
0.015668
P06576,P61421,Q9UDW1,P13073,Q9UHD1,O00483,P05141,P56134,O14745,P24539,O75947,P48047,Q9UJZ1,P47985,O75964,Q13423,P08574,Q00325
Processes and pathways
GO Biological process
msigdb_gobp
477,535,107,219,881,241,654,533,727,527,818,671,391,125,54,25,478,330
241,727,1824,815,818,54,1161,1835,654,477,478,1343,1070,219,1345,1072,1348,1545,527,1934,996,1079,3025,2873,1455,125,671,533,535,330,25,1216,1505,2565,107,881,1714,391
1.1260602689980173,0.5446668824908113,-0.13058070315460985,0.4901039644802168,0.4901039644802168,2.1506418231566373,0.26883090389803893,-0.13058070315460985,0.598934426926407,0.7599973733245824,0.7599973733245824,0.15633251874022483,0.32460928917017773,1.1772838549439275,0.15633251874022483,0.32460928917017773,0.15633251874022483,0.04255405207435462,0.7065964713851883,-0.18896601992068227,0.38007859388666043,0.32460928917017773,-1.3687923128782735,-1.0444731823352504,0.09960517303232037,1.5287351424822555,0.598934426926407,0.7065964713851883,0.7065964713851883,0.9708057586304926,3.2072507817126157,0.26883090389803893,0.09960517303232037,-0.6075273683129577,1.6756866487455853,0.4901039644802168,-0.014824683336963967,0.9185169053570901
3,216
Glycosylation
12
39
2.397042
0.016528
P39656,Q86YN1,O75503,P33908,P04844,Q10471,O60762,O60502,Q2TAA5,O43505,Q9NR45,Q9H488
Processes and pathways
GO Biological process
msigdb_gobp
365,229,274,130,246,281,302,17,80,108,297,60
892,895,108,17,985,302,1912,986,274,650,1066,906,246,130,365,1657,2383,689,2139,2847,281,1374,764,80,1291,1489,621,229,2492,870,2674,3088,1806,60,297,1712,881,2430,420
0.4352423338200509,0.4352423338200509,1.62694013996398,3.8944812172553123,0.38007859388666043,1.0228240276985572,-0.18896601992068227,0.38007859388666043,1.0745745880220183,0.598934426926407,0.32460928917017773,0.4352423338200509,1.1260602689980173,1.4792718527358455,0.9185169053570901,-0.014824683336963967,-0.48613310875494586,0.598934426926407,-0.3067719053974511,-0.9808631043501542,1.0745745880220183,0.15633251874022483,0.5446668824908113,1.8205302691917176,0.21273986061826164,0.09960517303232037,0.6529098806119115,1.1772838549439275,-0.546645177342604,0.4901039644802168,-0.7304210297875838,-1.6361198796349998,-0.07253494183063504,2.104137155032703,1.0745745880220183,-0.014824683336963967,0.4901039644802168,-0.48613310875494586,0.8659545453435412
3,216
Respiratory chain
15
28
2.355344
0.018506
Q9UDW1,Q96CU9,O75380,Q6DKK2,Q16795,O75306,O00483,O95182,O95168,O43678,P47985,P49821,O43674,P08574,O75489
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
107,450,70,618,72,162,241,522,580,21,125,325,57,478,398
241,57,21,815,162,70,398,580,522,1439,1443,1161,478,659,1173,1549,1079,125,325,836,3084,72,618,2330,450,1048,107,2516
1.1260602689980173,2.104137155032703,3.4551147492200505,0.4901039644802168,1.3294092295054736,1.9159521152124348,0.8659545453435412,0.6529098806119115,0.7065964713851883,0.09960517303232037,0.09960517303232037,0.26883090389803893,0.7599973733245824,0.598934426926407,0.26883090389803893,0.04255405207435462,0.32460928917017773,1.5287351424822555,0.9708057586304926,0.4901039644802168,-1.6361198796349998,1.9159521152124348,0.6529098806119115,-0.4259865462215386,0.8131157079420699,0.38007859388666043,1.6756866487455853,-0.546645177342604
3,216
SLC25 family of mitochondrial transporters
9
18
2.35441
0.018552
Q9H2D1,Q9UBX3,O43772,Q70HW3,O43808,Q9Y6C9,Q9NZJ7,P53007,Q00325
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
1,236,5,7,96,78,124,326,330
5,96,359,654,1070,584,326,330,757,619,7,2722,1,2174,124,236,883,78
5.247861600040695,1.6756866487455853,0.9185169053570901,0.598934426926407,0.32460928917017773,0.6529098806119115,0.9708057586304926,0.9708057586304926,0.5446668824908113,0.6529098806119115,5.213527788933368,-0.7924421870337799,6.1027541191014,-0.3067719053974511,1.5779570986245492,1.1772838549439275,0.4901039644802168,1.868353764466578
3,216
Mitochondrial carrier domain superfamily [IPR023395]
9
18
2.35441
0.018552
Q9H2D1,Q9UBX3,O43772,Q70HW3,O43808,Q9Y6C9,Q9NZJ7,P53007,Q00325
Sequence
InterPro Superfamily
interpro_homologous_superfamily
1,236,5,7,96,78,124,326,330
5,96,359,654,1070,584,326,330,757,619,7,2722,1,2174,124,236,883,78
5.247861600040695,1.6756866487455853,0.9185169053570901,0.598934426926407,0.32460928917017773,0.6529098806119115,0.9708057586304926,0.9708057586304926,0.5446668824908113,0.6529098806119115,5.213527788933368,-0.7924421870337799,6.1027541191014,-0.3067719053974511,1.5779570986245492,1.1772838549439275,0.4901039644802168,1.868353764466578
3,216
Mitochondrial substrate/solute carrier [IPR018108]
9
18
2.35441
0.018552
Q9H2D1,Q9UBX3,O43772,Q70HW3,O43808,Q9Y6C9,Q9NZJ7,P53007,Q00325
Sequence
InterPro Repeat
interpro_repeat
1,236,5,7,96,78,124,326,330
5,96,359,654,1070,584,326,330,757,619,7,2722,1,2174,124,236,883,78
5.247861600040695,1.6756866487455853,0.9185169053570901,0.598934426926407,0.32460928917017773,0.6529098806119115,0.9708057586304926,0.9708057586304926,0.5446668824908113,0.6529098806119115,5.213527788933368,-0.7924421870337799,6.1027541191014,-0.3067719053974511,1.5779570986245492,1.1772838549439275,0.4901039644802168,1.868353764466578
3,216
Tetrapyrrole binding
6
13
2.354333
0.018556
P09601,Q96EY8,P30519,Q16850,P12931,O43169
Functions
GO Molecular function
msigdb_gomf
2,105,11,284,138,27
726,27,478,2,138,1260,11,1953,284,105,1994,385,1327
0.5446668824908113,2.953211606238473,0.7599973733245824,5.782242867167574,1.4295647732720183,0.21273986061826164,4.5384813683737315,-0.18896601992068227,1.0745745880220183,1.6756866487455853,-0.18896601992068227,0.9185169053570901,0.21273986061826164
3,216
Oxidative phosphorylation
19
27
2.353971
0.018574
O00483,O43678,O75489,Q15904,O75306,O95182,P19404,P24539,O75964,P56134,O43674,O75380,Q16795,O75947,P48047,P49821,O75251,O95168,P06576
Processes and pathways
WikiPathways
msigdb_wp
241,21,398,164,162,522,659,527,54,533,57,70,72,818,671,325,815,580,477
241,57,21,815,162,70,398,818,54,580,522,1439,1443,477,659,527,1934,1549,671,325,836,533,164,3084,72,2330,2516
1.1260602689980173,2.104137155032703,3.4551147492200505,0.4901039644802168,1.3294092295054736,1.9159521152124348,0.8659545453435412,0.4901039644802168,2.1506418231566373,0.6529098806119115,0.7065964713851883,0.09960517303232037,0.09960517303232037,0.7599973733245824,0.598934426926407,0.7065964713851883,-0.18896601992068227,0.04255405207435462,0.598934426926407,0.9708057586304926,0.4901039644802168,0.7065964713851883,1.3294092295054736,-1.6361198796349998,1.9159521152124348,-0.4259865462215386,-0.546645177342604
3,216
transferase
13
30
2.332656
0.019666
P19623,P36957,P21266,O14772,Q32NB8,P49903,Q99735,P28161,Q2TAA5,O43505,P55809,P43490,P25325
Functions
Panther Protein class
panther_protein_class
425,595,427,514,616,672,453,590,80,108,30,118,176
893,514,1820,108,1732,1536,2292,1836,425,427,176,590,665,595,918,118,2303,672,2656,30,1856,80,616,1022,1214,453,1610,1515,1228,1056
0.4352423338200509,0.7065964713851883,-0.13058070315460985,1.62694013996398,-0.07253494183063504,0.04255405207435462,-0.4259865462215386,-0.13058070315460985,0.8131157079420699,0.8131157079420699,1.2789556593345546,0.6529098806119115,0.598934426926407,0.6529098806119115,0.4352423338200509,1.5779570986245492,-0.4259865462215386,0.598934426926407,-0.7304210297875838,2.823775345048234,-0.13058070315460985,1.8205302691917176,0.6529098806119115,0.38007859388666043,0.26883090389803893,0.8131157079420699,0.04255405207435462,0.09960517303232037,0.26883090389803893,0.38007859388666043
3,216
Oxidoreduction driven active transmembrane transporter activity
14
27
2.316791
0.020515
Q9UDW1,O75380,Q16795,P13073,O75306,O00483,O95182,O95168,O43678,P47985,P49821,O43674,P08574,O75489
Functions
GO Molecular function
msigdb_gomf
107,70,72,219,162,241,522,580,21,125,325,57,478,398
241,57,21,815,162,70,398,580,522,1439,1443,1161,478,1343,219,1345,659,1072,1549,1079,125,325,836,3084,72,107,2516
1.1260602689980173,2.104137155032703,3.4551147492200505,0.4901039644802168,1.3294092295054736,1.9159521152124348,0.8659545453435412,0.6529098806119115,0.7065964713851883,0.09960517303232037,0.09960517303232037,0.26883090389803893,0.7599973733245824,0.15633251874022483,1.1772838549439275,0.15633251874022483,0.598934426926407,0.32460928917017773,0.04255405207435462,0.32460928917017773,1.5287351424822555,0.9708057586304926,0.4901039644802168,-1.6361198796349998,1.9159521152124348,1.6756866487455853,-0.546645177342604
3,216
Flavin adenine dinucleotide binding
9
31
2.287546
0.022164
Q9Y2Z2,A1L0T0,Q15392,P50336,Q92947,P00387,O95831,P45954,Q8NB78
Functions
GO Molecular function
msigdb_gomf
128,511,6,279,379,198,58,530,29
511,808,1728,58,198,2363,1645,2029,994,3023,586,1452,1651,530,924,279,1585,6,936,1376,1980,854,29,379,2410,1304,792,1423,1626,128,1327
0.7065964713851883,0.4901039644802168,-0.07253494183063504,2.104137155032703,1.2282480860545921,-0.48613310875494586,-0.014824683336963967,-0.24769501940385638,0.38007859388666043,-1.3687923128782735,0.6529098806119115,0.09960517303232037,-0.014824683336963967,0.7065964713851883,0.4352423338200509,1.0745745880220183,0.04255405207435462,5.247861600040695,0.4352423338200509,0.15633251874022483,-0.18896601992068227,0.4901039644802168,2.867103951921783,0.9185169053570901,-0.48613310875494586,0.21273986061826164,0.5446668824908113,0.15633251874022483,0.04255405207435462,1.5287351424822555,0.21273986061826164
3,216
Translocase
9
18
2.285235
0.022299
O75306,P23634,Q9HD20,Q8NBU5,P49821,Q13423,P08574,P47985,O75489
Functions
Protein Atlas Molecular function
protein_atlas_molecular_function
162,46,51,189,325,25,478,125,398
815,162,398,1161,1835,477,478,1259,659,1931,46,1549,1455,125,325,25,189,51
0.4901039644802168,1.3294092295054736,0.8659545453435412,0.26883090389803893,-0.13058070315460985,0.7599973733245824,0.7599973733245824,0.21273986061826164,0.598934426926407,-0.18896601992068227,2.3345548914896983,0.04255405207435462,0.09960517303232037,1.5287351424822555,0.9708057586304926,3.2072507817126157,1.2789556593345546,2.1969339488404867
3,216
Membrane lipid metabolic process
15
30
2.244451
0.024803
Q96G23,P07602,Q96S52,Q99805,O15269,Q9NZ01,Q99735,P16278,Q92643,P06865,Q9NZJ7,Q9P0L0,O60762,Q53H12,O95470
Processes and pathways
GO Biological process
msigdb_gobp
69,64,345,43,578,414,453,249,261,655,124,637,302,440,361
578,981,302,361,1066,1165,655,64,2026,249,2751,661,1453,834,2976,1578,1964,440,2256,261,1400,69,345,453,43,2682,414,124,2178,637
0.6529098806119115,0.38007859388666043,1.0228240276985572,0.9185169053570901,0.32460928917017773,0.26883090389803893,0.598934426926407,1.9633274991781329,-0.24769501940385638,1.1260602689980173,-0.854852845001873,0.598934426926407,0.09960517303232037,0.4901039644802168,-1.2377883135314274,0.04255405207435462,-0.18896601992068227,0.8131157079420699,-0.36620096012652253,1.1260602689980173,0.15633251874022483,1.9633274991781329,0.9708057586304926,0.8131157079420699,2.425275325896919,-0.7304210297875838,0.8659545453435412,1.5779570986245492,-0.3067719053974511,0.6529098806119115
3,216
Glycerolipid biosynthetic process
14
44
2.242142
0.024952
Q8WVX9,Q8WTV0,Q8NF37,Q16822,Q96S52,Q32NB8,Q6IAN0,O15228,P17655,Q8WUK0,Q92643,Q9BTU6,O60762,Q92551
Processes and pathways
GO Biological process
msigdb_gobp
553,68,207,488,345,616,227,466,526,112,261,55,302,94
810,893,466,302,1535,1536,582,526,1649,997,2215,2303,1191,1095,1098,2232,2234,488,616,227,2612,1207,2404,207,2491,68,112,553,94,1397,261,1400,1693,1799,345,2564,1701,55,1610,1222,1229,1621,1142,1718
0.4901039644802168,0.4352423338200509,0.7599973733245824,1.0228240276985572,0.04255405207435462,0.04255405207435462,0.6529098806119115,0.7065964713851883,-0.014824683336963967,0.38007859388666043,-0.36620096012652253,-0.4259865462215386,0.26883090389803893,0.32460928917017773,0.32460928917017773,-0.36620096012652253,-0.36620096012652253,0.7599973733245824,0.6529098806119115,1.1772838549439275,-0.6687843869463775,0.26883090389803893,-0.48613310875494586,1.2282480860545921,-0.546645177342604,1.9633274991781329,1.62694013996398,0.7065964713851883,1.7241989713949182,0.15633251874022483,1.1260602689980173,0.15633251874022483,-0.014824683336963967,-0.07253494183063504,0.9708057586304926,-0.6075273683129577,-0.014824683336963967,2.1506418231566373,0.04255405207435462,0.26883090389803893,0.26883090389803893,0.04255405207435462,0.32460928917017773,-0.014824683336963967
3,216
Transporter complex
20
50
2.240992
0.025027
O00483,O43678,Q9Y5L4,P18433,O75489,P54709,Q92796,Q96CU9,O75306,O43674,O75380,Q16795,P62942,Q9Y5J9,Q8NE86,P49821,Q9Y276,Q9UDW1,P08574,P47985
Localization
GO Cellular component
msigdb_gocc
241,21,573,153,398,402,168,450,162,57,70,72,434,352,339,325,238,107,478,125
891,241,57,21,897,815,162,70,1339,398,580,522,1439,1443,1835,734,478,3022,2034,153,659,1173,1549,1079,125,325,836,2132,402,434,1969,2477,3084,72,1587,2330,946,339,1024,168,450,2262,955,1048,107,238,352,573,2744,2516
0.4352423338200509,1.1260602689980173,2.104137155032703,3.4551147492200505,0.4352423338200509,0.4901039644802168,1.3294092295054736,1.9159521152124348,0.15633251874022483,0.8659545453435412,0.6529098806119115,0.7065964713851883,0.09960517303232037,0.09960517303232037,-0.13058070315460985,0.5446668824908113,0.7599973733245824,-1.3687923128782735,-0.24769501940385638,1.3796114098899142,0.598934426926407,0.26883090389803893,0.04255405207435462,0.32460928917017773,1.5287351424822555,0.9708057586304926,0.4901039644802168,-0.3067719053974511,0.8659545453435412,0.8131157079420699,-0.18896601992068227,-0.546645177342604,-1.6361198796349998,1.9159521152124348,0.04255405207435462,-0.4259865462215386,0.4352423338200509,0.9708057586304926,0.38007859388666043,1.3294092295054736,0.8131157079420699,-0.36620096012652253,0.4352423338200509,0.38007859388666043,1.6756866487455853,1.1772838549439275,0.9708057586304926,0.7065964713851883,-0.7924421870337799,-0.546645177342604
3,216
Oxidoreductase activity acting on ch oh group of donors
30
51
2.230554
0.025711
P48507,Q8NBQ5,Q16836,O43488,Q7Z4W1,Q8N8N7,Q53GQ0,Q00796,P51648,Q9UBQ7,P00338,P20839,P31937,P12268,P14550,Q15738,P40926,Q8TC12,Q9Y394,P48735,Q8NBN7,Q6IAN0,P23368,P35270,Q99714,P56545,O60701,Q92506,Q6UWP2,P11413
Functions
GO Molecular function
msigdb_gomf
596,947,695,242,940,16,156,755,746,718,904,660,177,911,913,849,429,777,239,89,103,227,587,827,381,838,469,260,375,480
1155,242,2360,469,2198,904,1922,480,1344,911,913,1448,2121,660,587,177,827,2756,429,1458,1557,2216,596,89,2839,925,2130,746,1183,2047,2052,838,755,1581,849,695,1200,156,227,375,940,2721,16,103,947,777,260,381,1415,718,239
0.26883090389803893,1.1260602689980173,-0.48613310875494586,0.7599973733245824,-0.36620096012652253,0.4352423338200509,-0.18896601992068227,0.7599973733245824,0.15633251874022483,0.4352423338200509,0.4352423338200509,0.09960517303232037,-0.3067719053974511,0.598934426926407,0.6529098806119115,1.2789556593345546,0.4901039644802168,-0.854852845001873,0.8131157079420699,0.09960517303232037,0.04255405207435462,-0.36620096012652253,0.6529098806119115,1.7241989713949182,-0.9808631043501542,0.4352423338200509,-0.3067719053974511,0.5446668824908113,0.26883090389803893,-0.24769501940385638,-0.24769501940385638,0.4901039644802168,0.5446668824908113,0.04255405207435462,0.4901039644802168,0.598934426926407,0.26883090389803893,1.3796114098899142,1.1772838549439275,0.9185169053570901,0.4352423338200509,-0.7924421870337799,3.9335038093148667,1.6756866487455853,0.4352423338200509,0.5446668824908113,1.1260602689980173,0.9185169053570901,0.15633251874022483,0.598934426926407,1.1772838549439275
3,216
Glycoprotein metabolic process
28
48
2.214447
0.026798
P39656,O75352,P33908,P04844,Q02809,O60502,Q9Y673,Q14165,O00469,Q10471,Q99805,P62820,P04843,O95394,O15294,O60762,Q96JB2,Q9H488,O14734,Q86SF2,Q9UHD1,Q9H4A6,Q2TAA5,Q9H0U4,Q86YN1,O60701,O43505,P35610
Processes and pathways
GO Biological process
msigdb_gobp
365,986,130,246,689,17,420,764,892,281,43,683,906,650,895,302,870,60,644,621,881,347,80,1042,229,469,108,593
892,644,895,108,17,985,469,302,1912,986,650,906,246,1647,130,1753,593,365,1657,2383,683,689,2139,2847,281,1374,764,1965,80,1291,1489,621,229,2492,870,2674,1216,43,2166,3088,1042,1806,60,347,1519,1712,881,420
0.4352423338200509,0.598934426926407,0.4352423338200509,1.62694013996398,3.8944812172553123,0.38007859388666043,0.7599973733245824,1.0228240276985572,-0.18896601992068227,0.38007859388666043,0.598934426926407,0.4352423338200509,1.1260602689980173,-0.014824683336963967,1.4792718527358455,-0.07253494183063504,0.6529098806119115,0.9185169053570901,-0.014824683336963967,-0.48613310875494586,0.598934426926407,0.598934426926407,-0.3067719053974511,-0.9808631043501542,1.0745745880220183,0.15633251874022483,0.5446668824908113,-0.18896601992068227,1.8205302691917176,0.21273986061826164,0.09960517303232037,0.6529098806119115,1.1772838549439275,-0.546645177342604,0.4901039644802168,-0.7304210297875838,0.26883090389803893,2.425275325896919,-0.3067719053974511,-1.6361198796349998,0.38007859388666043,-0.07253494183063504,2.104137155032703,0.9708057586304926,0.09960517303232037,-0.014824683336963967,0.4901039644802168,0.8659545453435412
3,216
Proton transmembrane transporter activity
13
30
2.203487
0.02756
P06576,Q9UDW1,P13073,P05141,P56134,P24539,Q93050,O75964,P47985,P61421,Q13423,P08574,Q00325
Functions
GO Molecular function
msigdb_gomf
477,107,219,654,533,527,83,54,125,535,25,478,330
818,54,1250,1161,654,477,478,1343,1070,219,1345,1072,1348,1545,527,1934,1079,3025,2873,1455,125,671,533,535,330,25,83,107,1714,2100
0.4901039644802168,2.1506418231566373,0.21273986061826164,0.26883090389803893,0.598934426926407,0.7599973733245824,0.7599973733245824,0.15633251874022483,0.32460928917017773,1.1772838549439275,0.15633251874022483,0.32460928917017773,0.15633251874022483,0.04255405207435462,0.7065964713851883,-0.18896601992068227,0.32460928917017773,-1.3687923128782735,-1.0444731823352504,0.09960517303232037,1.5287351424822555,0.598934426926407,0.7065964713851883,0.7065964713851883,0.9708057586304926,3.2072507817126157,1.8205302691917176,1.6756866487455853,-0.014824683336963967,-0.24769501940385638
3,216
Protein targeting to mitochondrion
11
42
2.183427
0.029004
Q9NS69,P55786,O00170,Q8TAA5,Q8TB36,Q3ZCQ8,Q9Y5J9,P30536,O60830,O95831,P19784
Processes and pathways
GO Biological process
msigdb_gobp
0,32,240,340,104,253,352,19,24,58,399
240,1060,983,897,24,1063,1639,1640,900,2585,58,652,2587,2450,399,19,2651,1357,2046,32,928,1098,1578,2481,253,440,769,2775,340,104,3149,3054,1138,2731,0,2934,1051,2012,1902,976,352,573
1.1260602689980173,0.32460928917017773,0.38007859388666043,0.4352423338200509,3.2489818306311413,0.32460928917017773,-0.014824683336963967,-0.014824683336963967,0.4352423338200509,-0.6687843869463775,2.104137155032703,0.598934426926407,-0.6687843869463775,-0.546645177342604,0.8659545453435412,3.697105660578045,-0.7304210297875838,0.15633251874022483,-0.24769501940385638,2.7802613951530453,0.4352423338200509,0.32460928917017773,0.04255405207435462,-0.546645177342604,1.1260602689980173,0.8131157079420699,0.5446668824908113,-0.854852845001873,0.9708057586304926,1.6756866487455853,-2.1220907295805977,-1.4349500541120128,0.32460928917017773,-0.7924421870337799,6.5354785451653035,-1.1084937197910267,0.38007859388666043,-0.18896601992068227,-0.13058070315460985,0.4352423338200509,0.9708057586304926,0.7065964713851883
3,216
Phase ii conjugation of compounds
12
32
2.177083
0.029474
P48507,P21266,Q8TB61,Q9NUJ1,O60701,Q99735,P28161,O43708,O95861,Q96IU4,P78417,P21964
Processes and pathways
Reactome Pathways
msigdb_reactome
596,427,341,40,469,453,590,467,582,158,182,175
1820,1244,467,469,2441,1252,582,2522,913,427,175,1842,590,2595,1847,596,1083,182,2321,341,702,158,1405,1994,453,2001,1888,40,1812,882,1056,1239
-0.13058070315460985,0.21273986061826164,0.7599973733245824,0.7599973733245824,-0.546645177342604,0.21273986061826164,0.6529098806119115,-0.6075273683129577,0.4352423338200509,0.8131157079420699,1.2789556593345546,-0.13058070315460985,0.6529098806119115,-0.6687843869463775,-0.13058070315460985,0.6529098806119115,0.32460928917017773,1.2789556593345546,-0.4259865462215386,0.9708057586304926,0.598934426926407,1.3796114098899142,0.15633251874022483,-0.18896601992068227,0.8131157079420699,-0.18896601992068227,-0.13058070315460985,2.559853153319494,-0.07253494183063504,0.4901039644802168,0.38007859388666043,0.26883090389803893
3,216
Muscle abnormality related to mitochondrial dysfunction
11
34
2.176849
0.029492
Q9UBX3,Q96CU9,O75380,O75306,O00483,P54098,O75648,P49821,Q53H12,Q9UHN1,O75489
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
236,450,70,162,241,47,109,325,440,300,398
241,1246,815,162,70,398,109,473,1443,1161,1070,1345,659,1549,2042,325,1269,47,440,2330,3050,2406,450,1501,2565,2088,2416,1048,2933,236,300,975,807,2516
1.1260602689980173,0.21273986061826164,0.4901039644802168,1.3294092295054736,1.9159521152124348,0.8659545453435412,1.62694013996398,0.7599973733245824,0.09960517303232037,0.26883090389803893,0.32460928917017773,0.15633251874022483,0.598934426926407,0.04255405207435462,-0.24769501940385638,0.9708057586304926,0.21273986061826164,2.3345548914896983,0.8131157079420699,-0.4259865462215386,-1.4349500541120128,-0.48613310875494586,0.8131157079420699,0.09960517303232037,-0.6075273683129577,-0.24769501940385638,-0.48613310875494586,0.38007859388666043,-1.1084937197910267,1.1772838549439275,1.0745745880220183,0.4352423338200509,0.5446668824908113,-0.546645177342604
3,216
Glycosyl compound metabolic process
12
31
2.160518
0.030733
Q9BTY2,O43488,P23919,O60294,Q9NUJ1,Q9BQ69,O60256,Q9Y315,Q13126,Q9NRW3,O43598,O60725
Processes and pathways
GO Biological process
msigdb_gobp
169,242,588,217,40,41,520,115,15,565,355,28
242,355,520,217,28,653,1162,1066,820,1165,2292,1836,583,913,1448,588,1551,3129,832,2133,750,1766,1856,15,2721,41,169,565,40,115,3039
1.1260602689980173,0.9185169053570901,0.7065964713851883,1.1772838549439275,2.9102488385419973,0.598934426926407,0.26883090389803893,0.32460928917017773,0.4901039644802168,0.26883090389803893,-0.4259865462215386,-0.13058070315460985,0.6529098806119115,0.4352423338200509,0.09960517303232037,0.6529098806119115,0.04255405207435462,-1.9807820245726757,0.4901039644802168,-0.3067719053974511,0.5446668824908113,-0.07253494183063504,-0.13058070315460985,4.126418509720479,-0.7924421870337799,2.5151918167778486,1.3294092295054736,0.7065964713851883,2.559853153319494,1.62694013996398,-1.3687923128782735
3,216
Glycosyltransferase
8
33
2.154459
0.031204
Q10471,Q9UGN5,Q13126,Q2TAA5,O43505,P43490,O60762,Q9H488
Functions
Protein Atlas Molecular function
protein_atlas_molecular_function
281,269,15,80,108,118,302,60
895,108,985,302,653,1162,1066,2025,2292,2294,1836,1837,1257,2698,118,1657,3060,1856,281,15,2149,80,1489,621,1789,2492,2674,3088,1806,60,1712,269,420
0.4352423338200509,1.62694013996398,0.38007859388666043,1.0228240276985572,0.598934426926407,0.26883090389803893,0.32460928917017773,-0.24769501940385638,-0.4259865462215386,-0.4259865462215386,-0.13058070315460985,-0.13058070315460985,0.21273986061826164,-0.7924421870337799,1.5779570986245492,-0.014824683336963967,-1.5015530517801203,-0.13058070315460985,1.0745745880220183,4.126418509720479,-0.3067719053974511,1.8205302691917176,0.09960517303232037,0.6529098806119115,-0.07253494183063504,-0.546645177342604,-0.7304210297875838,-1.6361198796349998,-0.07253494183063504,2.104137155032703,-0.014824683336963967,1.1260602689980173,0.8659545453435412
3,216
Glycerophospholipid biosynthetic process
12
40
2.138476
0.032478
Q8WVX9,Q8NF37,Q6IAN0,Q96S52,Q32NB8,O15228,P17655,Q8WUK0,Q92643,Q9BTU6,O60762,Q92551
Processes and pathways
GO Biological process
msigdb_gobp
553,207,227,345,616,466,526,112,261,55,302,94
810,893,466,302,1535,1536,582,526,1649,2215,2303,1191,1095,1098,2232,2234,616,227,2612,1207,2404,207,2491,112,553,94,261,1400,1693,1799,345,2564,1701,55,1610,1222,1229,1621,1142,1718
0.4901039644802168,0.4352423338200509,0.7599973733245824,1.0228240276985572,0.04255405207435462,0.04255405207435462,0.6529098806119115,0.7065964713851883,-0.014824683336963967,-0.36620096012652253,-0.4259865462215386,0.26883090389803893,0.32460928917017773,0.32460928917017773,-0.36620096012652253,-0.36620096012652253,0.6529098806119115,1.1772838549439275,-0.6687843869463775,0.26883090389803893,-0.48613310875494586,1.2282480860545921,-0.546645177342604,1.62694013996398,0.7065964713851883,1.7241989713949182,1.1260602689980173,0.15633251874022483,-0.014824683336963967,-0.07253494183063504,0.9708057586304926,-0.6075273683129577,-0.014824683336963967,2.1506418231566373,0.04255405207435462,0.26883090389803893,0.26883090389803893,0.04255405207435462,0.32460928917017773,-0.014824683336963967
3,216
Oxidative phosphorylation
23
53
2.134822
0.032776
P61586,P06576,O00483,P14635,O43678,O75489,O75306,O95182,P19404,P24539,O75964,P56134,O43674,O75380,Q16795,P34897,P49821,Q9UDW1,P13073,O95168,Q9UJZ1,P08574,P47985
Processes and pathways
GO Biological process
msigdb_gobp
603,477,241,140,21,398,162,522,659,527,54,533,57,70,72,666,325,107,219,580,391,478,125
241,57,21,815,162,2801,70,398,818,54,580,522,1439,1443,1161,907,477,478,1645,1343,219,140,659,1072,1173,527,1934,1549,996,1651,1079,666,3025,1656,125,671,325,836,2051,533,603,3084,72,1977,1018,1307,1216,1038,2416,2002,107,391,2516
1.1260602689980173,2.104137155032703,3.4551147492200505,0.4901039644802168,1.3294092295054736,-0.9176580886776406,1.9159521152124348,0.8659545453435412,0.4901039644802168,2.1506418231566373,0.6529098806119115,0.7065964713851883,0.09960517303232037,0.09960517303232037,0.26883090389803893,0.4352423338200509,0.7599973733245824,0.7599973733245824,-0.014824683336963967,0.15633251874022483,1.1772838549439275,1.4295647732720183,0.598934426926407,0.32460928917017773,0.26883090389803893,0.7065964713851883,-0.18896601992068227,0.04255405207435462,0.38007859388666043,-0.014824683336963967,0.32460928917017773,0.598934426926407,-1.3687923128782735,-0.014824683336963967,1.5287351424822555,0.598934426926407,0.9708057586304926,0.4901039644802168,-0.24769501940385638,0.7065964713851883,0.6529098806119115,-1.6361198796349998,1.9159521152124348,-0.18896601992068227,0.38007859388666043,0.21273986061826164,0.26883090389803893,0.38007859388666043,-0.48613310875494586,-0.18896601992068227,1.6756866487455853,0.9185169053570901,-0.546645177342604
3,216
Mitochondrial membrane organization
14
43
2.132527
0.032964
Q9NS69,P45880,Q9Y276,Q9NVH1,Q6UXV4,Q8IXI2,Q8IWA4,Q16891,Q3ZCQ8,Q9Y5J9,Q9BUR5,Q13505,Q9Y5L4,Q53H12
Processes and pathways
GO Biological process
msigdb_gobp
0,66,238,507,376,552,442,615,253,352,159,26,573,440
2192,897,1246,731,1639,1640,1250,1445,654,2587,1169,3022,1070,996,665,2651,2599,829,66,1847,1360,2876,1467,26,615,253,440,2483,376,442,1116,552,1211,159,2002,0,507,1710,238,642,976,352,573
-0.36620096012652253,0.4352423338200509,0.21273986061826164,0.5446668824908113,-0.014824683336963967,-0.014824683336963967,0.21273986061826164,0.09960517303232037,0.598934426926407,-0.6687843869463775,0.26883090389803893,-1.3687923128782735,0.32460928917017773,0.38007859388666043,0.598934426926407,-0.7304210297875838,-0.6687843869463775,0.4901039644802168,1.9633274991781329,-0.13058070315460985,0.15633251874022483,-1.0444731823352504,0.09960517303232037,3.2072507817126157,0.6529098806119115,1.1260602689980173,0.8131157079420699,-0.546645177342604,0.9185169053570901,0.8131157079420699,0.32460928917017773,0.7065964713851883,0.26883090389803893,1.3796114098899142,-0.18896601992068227,6.5354785451653035,0.7599973733245824,-0.014824683336963967,1.1772838549439275,0.6529098806119115,0.4352423338200509,0.9708057586304926,0.7065964713851883
3,216
oxidoreductase
14
43
2.121664
0.033866
O75380,Q16795,Q99714,Q9BUP3,O75306,O00483,Q08257,Q9Y320,Q92506,O43678,P49821,O43674,O95831,O43169
Functions
Panther Protein class
panther_protein_class
70,72,381,74,162,241,77,351,260,21,325,57,58,27
241,27,812,57,21,162,70,580,522,58,1443,1161,3171,1645,994,586,915,587,2697,2213,2216,325,836,2535,77,1585,936,3084,72,1200,3046,375,2330,2721,260,1304,2859,381,74,2899,1048,351,2516
1.1260602689980173,2.953211606238473,0.4901039644802168,2.104137155032703,3.4551147492200505,1.3294092295054736,1.9159521152124348,0.6529098806119115,0.7065964713851883,2.104137155032703,0.09960517303232037,0.26883090389803893,-2.4844975409145102,-0.014824683336963967,0.38007859388666043,0.6529098806119115,0.4352423338200509,0.6529098806119115,-0.7924421870337799,-0.36620096012652253,-0.36620096012652253,0.9708057586304926,0.4901039644802168,-0.6075273683129577,1.868353764466578,0.04255405207435462,0.4352423338200509,-1.6361198796349998,1.9159521152124348,0.26883090389803893,-1.4349500541120128,0.9185169053570901,-0.4259865462215386,-0.7924421870337799,1.1260602689980173,0.21273986061826164,-0.9808631043501542,0.9185169053570901,1.9159521152124348,-1.0444731823352504,0.38007859388666043,0.9708057586304926,-0.546645177342604
3,216
Exercise intolerance
7
32
2.113487
0.034559
Q9Y276,Q9H2D1,Q92947,Q8NI60,P54098,P23786,Q9UHN1
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
238,1,379,208,47,76,300
904,1161,1642,1539,2364,1070,1257,76,1547,1177,1651,1556,1458,2217,47,2052,3182,440,1022,208,379,1501,787,2416,1,792,1618,300,238,974,975,807
0.4352423338200509,0.26883090389803893,-0.014824683336963967,0.04255405207435462,-0.48613310875494586,0.32460928917017773,0.21273986061826164,1.868353764466578,0.04255405207435462,0.26883090389803893,-0.014824683336963967,0.04255405207435462,0.09960517303232037,-0.36620096012652253,2.3345548914896983,-0.24769501940385638,-2.7843617665368554,0.8131157079420699,0.38007859388666043,1.2282480860545921,0.9185169053570901,0.09960517303232037,0.5446668824908113,-0.48613310875494586,6.1027541191014,0.5446668824908113,0.04255405207435462,1.0745745880220183,1.1772838549439275,0.4352423338200509,0.4352423338200509,0.5446668824908113
3,216
Phase i functionalization of compounds
7
16
2.111451
0.034734
P05091,O00170,P30837,Q16850,P07099,P00387,O43169
Processes and pathways
Reactome Pathways
msigdb_reactome
247,240,34,284,13,198,27
240,27,198,247,13,2448,1344,586,915,34,1968,284,549,314,864,797
1.1260602689980173,2.953211606238473,1.2282480860545921,1.1260602689980173,4.42772984322683,-0.546645177342604,0.15633251874022483,0.6529098806119115,0.4352423338200509,2.6926708657040783,-0.18896601992068227,1.0745745880220183,0.7065964713851883,1.0228240276985572,0.4901039644802168,0.5446668824908113
3,216
Respiratory electron transport chain
14
46
2.108677
0.034972
Q9UDW1,O75380,Q16795,P13073,O75306,O00483,P14635,O43678,P47985,P49821,O43674,O75746,Q9UHN1,O43819
Processes and pathways
GO Biological process
msigdb_gobp
107,70,72,219,162,241,140,21,125,325,57,359,300,173
241,57,21,173,815,162,70,398,359,580,522,1439,1443,1161,1066,3171,907,478,1645,1343,219,994,140,659,1072,1746,1549,1651,2213,1557,125,325,836,2238,936,3084,72,1977,1216,2898,2416,2002,107,300,883,2516
1.1260602689980173,2.104137155032703,3.4551147492200505,1.2789556593345546,0.4901039644802168,1.3294092295054736,1.9159521152124348,0.8659545453435412,0.9185169053570901,0.6529098806119115,0.7065964713851883,0.09960517303232037,0.09960517303232037,0.26883090389803893,0.32460928917017773,-2.4844975409145102,0.4352423338200509,0.7599973733245824,-0.014824683336963967,0.15633251874022483,1.1772838549439275,0.38007859388666043,1.4295647732720183,0.598934426926407,0.32460928917017773,-0.07253494183063504,0.04255405207435462,-0.014824683336963967,-0.36620096012652253,0.04255405207435462,1.5287351424822555,0.9708057586304926,0.4901039644802168,-0.36620096012652253,0.4352423338200509,-1.6361198796349998,1.9159521152124348,-0.18896601992068227,0.26883090389803893,-1.0444731823352504,-0.48613310875494586,-0.18896601992068227,1.6756866487455853,1.0745745880220183,0.4901039644802168,-0.546645177342604
3,216
Acyltransferase
14
35
2.087771
0.036818
P36957,Q9BWD1,Q9NWU1,Q86UY6,Q8NF37,O75600,P09110,P35610,P23786,O15228,O15269,O14929,O95251,Q9NPF4
Functions
Protein Atlas Molecular function
protein_atlas_molecular_function
595,134,136,377,207,244,248,593,76,466,578,396,360,504
396,466,578,981,2193,244,360,248,1342,823,2207,76,1546,665,593,595,1844,829,3115,2052,2612,1207,377,207,1397,1796,1799,1701,134,2505,2269,961,504,136,1899
0.8659545453435412,0.7599973733245824,0.6529098806119115,0.38007859388666043,-0.36620096012652253,1.1260602689980173,0.9185169053570901,1.1260602689980173,0.15633251874022483,0.4901039644802168,-0.36620096012652253,1.868353764466578,0.04255405207435462,0.598934426926407,0.6529098806119115,0.6529098806119115,-0.13058070315460985,0.4901039644802168,-1.8414697677680782,-0.24769501940385638,-0.6687843869463775,0.26883090389803893,0.9185169053570901,1.2282480860545921,0.15633251874022483,-0.07253494183063504,-0.07253494183063504,-0.014824683336963967,1.4792718527358455,-0.546645177342604,-0.36620096012652253,0.4352423338200509,0.7599973733245824,1.4792718527358455,-0.13058070315460985
3,216
Mitochondrial protein import
11
35
2.083872
0.037172
Q9NS69,Q9Y276,P21796,Q8TAA5,Q3ZCQ8,Q9Y5J9,O60830,O75746,Q13505,P08574,P06576
Processes and pathways
Reactome Pathways
msigdb_reactome
0,238,65,340,253,352,24,359,26,478,477
1060,983,897,24,1732,731,1063,359,1639,652,477,478,2450,1070,584,65,1934,2599,2130,1098,26,253,769,1977,340,1506,3212,2731,0,1710,883,238,976,352,573
0.32460928917017773,0.38007859388666043,0.4352423338200509,3.2489818306311413,-0.07253494183063504,0.5446668824908113,0.32460928917017773,0.9185169053570901,-0.014824683336963967,0.598934426926407,0.7599973733245824,0.7599973733245824,-0.546645177342604,0.32460928917017773,0.6529098806119115,1.9633274991781329,-0.18896601992068227,-0.6687843869463775,-0.3067719053974511,0.32460928917017773,3.2072507817126157,1.1260602689980173,0.5446668824908113,-0.18896601992068227,0.9708057586304926,0.09960517303232037,-5.4830992734920185,-0.7924421870337799,6.5354785451653035,-0.014824683336963967,0.4901039644802168,1.1772838549439275,0.4352423338200509,0.9708057586304926,0.7065964713851883
3,216
Cation transmembrane transporter activity
22
61
2.075284
0.03796
P06576,O43772,Q70HW3,Q9H9B4,Q13423,P23634,P24539,Q9HD20,P61421,O75964,Q8NE86,Q93050,Q9BXP2,Q6P4Q7,Q00325,Q9UDW1,P13073,O43808,Q96NB2,Q15758,P08574,P47985
Functions
GO Molecular function
msigdb_gomf
477,5,7,296,25,46,527,51,535,54,339,83,499,87,330,107,219,96,113,373,478,125
5,96,818,54,1250,1161,1835,734,654,477,2117,2750,1644,478,1343,1070,219,1345,1259,1931,1072,1348,1545,46,527,1934,1650,1079,3025,2873,1455,125,671,2758,533,535,1367,330,841,25,373,1587,87,7,2722,339,1302,83,113,3207,786,499,2001,296,2174,51,107,1714,1627,2100,890
5.247861600040695,1.6756866487455853,0.4901039644802168,2.1506418231566373,0.21273986061826164,0.26883090389803893,-0.13058070315460985,0.5446668824908113,0.598934426926407,0.7599973733245824,-0.3067719053974511,-0.854852845001873,-0.014824683336963967,0.7599973733245824,0.15633251874022483,0.32460928917017773,1.1772838549439275,0.15633251874022483,0.21273986061826164,-0.18896601992068227,0.32460928917017773,0.15633251874022483,0.04255405207435462,2.3345548914896983,0.7065964713851883,-0.18896601992068227,-0.014824683336963967,0.32460928917017773,-1.3687923128782735,-1.0444731823352504,0.09960517303232037,1.5287351424822555,0.598934426926407,-0.854852845001873,0.7065964713851883,0.7065964713851883,0.15633251874022483,0.9708057586304926,0.4901039644802168,3.2072507817126157,0.9185169053570901,0.04255405207435462,1.7724794192359936,5.213527788933368,-0.7924421870337799,0.9708057586304926,0.21273986061826164,1.8205302691917176,1.62694013996398,-4.621457222623344,0.5446668824908113,0.7599973733245824,-0.18896601992068227,1.0745745880220183,-0.3067719053974511,2.1969339488404867,1.6756866487455853,-0.014824683336963967,0.04255405207435462,-0.24769501940385638,0.4901039644802168
3,216
Nonalcoholic fatty liver disease
15
45
2.046451
0.040712
Q9UDW1,O75380,Q16795,P13073,O75306,O00483,O95182,O95168,O43678,P47985,P49821,O43674,P08574,P54646,O75489
Processes and pathways
WikiPathways
msigdb_wp
107,70,72,219,162,241,522,580,21,125,325,57,478,599,398
241,57,21,815,162,70,398,580,522,1439,1443,1161,1255,478,1343,219,1345,659,1072,1746,1173,1549,1651,1079,1356,125,2839,325,1360,836,1567,599,1270,1089,1188,2538,1578,3084,72,2330,2341,869,1048,107,2516
1.1260602689980173,2.104137155032703,3.4551147492200505,0.4901039644802168,1.3294092295054736,1.9159521152124348,0.8659545453435412,0.6529098806119115,0.7065964713851883,0.09960517303232037,0.09960517303232037,0.26883090389803893,0.21273986061826164,0.7599973733245824,0.15633251874022483,1.1772838549439275,0.15633251874022483,0.598934426926407,0.32460928917017773,-0.07253494183063504,0.26883090389803893,0.04255405207435462,-0.014824683336963967,0.32460928917017773,0.15633251874022483,1.5287351424822555,-0.9808631043501542,0.9708057586304926,0.15633251874022483,0.4901039644802168,0.04255405207435462,0.6529098806119115,0.21273986061826164,0.32460928917017773,0.26883090389803893,-0.6075273683129577,0.04255405207435462,-1.6361198796349998,1.9159521152124348,-0.4259865462215386,-0.4259865462215386,0.4901039644802168,0.38007859388666043,1.6756866487455853,-0.546645177342604
3,216
Ventricular arrhythmia
8
36
2.03913
0.041437
O43772,P50336,O75306,P54098,P23786,Q9BTV4,O60783,Q9UHN1
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
5,279,162,47,76,294,174,300
5,174,162,2694,1161,2642,733,2293,3022,2992,1070,323,1927,2366,1746,76,669,1556,1844,924,2914,279,1000,47,756,2848,2314,1394,1022,1604,1303,2496,1501,294,1048,300
5.247861600040695,1.2789556593345546,1.3294092295054736,-0.7924421870337799,0.26883090389803893,-0.7304210297875838,0.5446668824908113,-0.4259865462215386,-1.3687923128782735,-1.3030737250573206,0.32460928917017773,0.9708057586304926,-0.18896601992068227,-0.48613310875494586,-0.07253494183063504,1.868353764466578,0.598934426926407,0.04255405207435462,-0.13058070315460985,0.4352423338200509,-1.1084937197910267,1.0745745880220183,0.38007859388666043,2.3345548914896983,0.5446668824908113,-0.9808631043501542,-0.4259865462215386,0.15633251874022483,0.38007859388666043,0.04255405207435462,0.21273986061826164,-0.546645177342604,0.09960517303232037,1.0745745880220183,0.38007859388666043,1.0745745880220183
3,216
Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen
11
29
2.033529
0.041999
Q6P6C2,P09601,Q8IVL6,Q8IUF8,P16435,Q32P28,P30519,Q16850,Q9BU89,Q8NB78,O95864
Functions
GO Molecular function
msigdb_gomf
228,2,286,622,586,617,11,284,295,29,423
892,2518,982,1728,985,2024,2112,423,2116,2,912,586,742,11,2997,689,2311,284,617,228,2668,622,286,29,1874,295,1612,2794,2280
0.4352423338200509,-0.6075273683129577,0.38007859388666043,-0.07253494183063504,0.38007859388666043,-0.24769501940385638,-0.3067719053974511,0.8131157079420699,-0.3067719053974511,5.782242867167574,0.4352423338200509,0.6529098806119115,0.5446668824908113,4.5384813683737315,-1.3030737250573206,0.598934426926407,-0.4259865462215386,1.0745745880220183,0.6529098806119115,1.1772838549439275,-0.7304210297875838,0.6529098806119115,1.0745745880220183,2.867103951921783,-0.13058070315460985,1.0745745880220183,0.04255405207435462,-0.854852845001873,-0.36620096012652253
3,216
Cellular hormone metabolic process
8
17
2.024442
0.042925
Q8NBN7,Q99714,Q92506,P30536,Q6UWP2,Q53GQ0,Q9HB40,Q9Y394
Processes and pathways
GO Biological process
msigdb_gobp
103,381,260,19,375,156,88,239
730,361,1448,19,1183,2886,156,1290,375,103,947,777,260,381,88,1415,239
0.5446668824908113,0.9185169053570901,0.09960517303232037,3.697105660578045,0.26883090389803893,-1.0444731823352504,1.3796114098899142,0.21273986061826164,0.9185169053570901,1.6756866487455853,0.4352423338200509,0.5446668824908113,1.1260602689980173,0.9185169053570901,1.7724794192359936,0.15633251874022483,1.1772838549439275
3,216
Xenobiotic metabolic process
8
15
2.00345
0.045129
P21266,O00170,P16435,P09110,Q08257,P07099,P78417,O43169
Processes and pathways
GO Biological process
msigdb_gobp
427,240,586,248,77,13,182,27
240,27,13,248,2121,586,427,590,997,182,77,864,2001,1888,1239
1.1260602689980173,2.953211606238473,4.42772984322683,1.1260602689980173,-0.3067719053974511,0.6529098806119115,0.8131157079420699,0.6529098806119115,0.38007859388666043,1.2789556593345546,1.868353764466578,0.4901039644802168,-0.18896601992068227,-0.13058070315460985,0.26883090389803893
3,216
Respiratory electron transport
16
46
2.00181
0.045305
Q9UDW1,O75380,Q16795,P13073,O75306,O00483,O75880,Q9BQ95,Q7L592,O43678,P47985,P49821,O43674,P08574,O75489,O43819
Processes and pathways
Reactome Pathways
msigdb_reactome
107,70,72,219,162,241,470,456,337,21,125,325,57,478,398,173
241,57,21,173,815,162,70,398,470,580,522,1439,1443,1161,478,1343,219,994,1345,659,1072,1746,1173,1549,1651,1079,2213,2042,125,325,836,1669,936,3084,72,337,2330,3050,456,2565,792,1048,2933,107,2516,2691
1.1260602689980173,2.104137155032703,3.4551147492200505,1.2789556593345546,0.4901039644802168,1.3294092295054736,1.9159521152124348,0.8659545453435412,0.7599973733245824,0.6529098806119115,0.7065964713851883,0.09960517303232037,0.09960517303232037,0.26883090389803893,0.7599973733245824,0.15633251874022483,1.1772838549439275,0.38007859388666043,0.15633251874022483,0.598934426926407,0.32460928917017773,-0.07253494183063504,0.26883090389803893,0.04255405207435462,-0.014824683336963967,0.32460928917017773,-0.36620096012652253,-0.24769501940385638,1.5287351424822555,0.9708057586304926,0.4901039644802168,-0.014824683336963967,0.4352423338200509,-1.6361198796349998,1.9159521152124348,0.9708057586304926,-0.4259865462215386,-1.4349500541120128,0.8131157079420699,-0.6075273683129577,0.5446668824908113,0.38007859388666043,-1.1084937197910267,1.6756866487455853,-0.546645177342604,-0.7304210297875838
3,216
Amide transport
11
37
1.986563
0.046971
Q9H2D1,Q16836,P07602,Q16822,O00233,P80404,P62820,Q8NE86,Q9NZJ7,Q9P0L0,P55809
Processes and pathways
GO Biological process
msigdb_gobp
1,695,64,488,463,251,683,339,124,637,30
1150,463,727,1532,988,905,2290,64,2364,2032,1743,661,2525,1458,3115,2704,30,683,251,1854,1855,1278,1577,1962,1582,488,695,2396,1984,339,1028,1216,1038,1,124,637,2573
0.26883090389803893,0.7599973733245824,0.5446668824908113,0.04255405207435462,0.38007859388666043,0.4352423338200509,-0.4259865462215386,1.9633274991781329,-0.48613310875494586,-0.24769501940385638,-0.07253494183063504,0.598934426926407,-0.6075273683129577,0.09960517303232037,-1.8414697677680782,-0.7924421870337799,2.823775345048234,0.598934426926407,1.1260602689980173,-0.13058070315460985,-0.13058070315460985,0.21273986061826164,0.04255405207435462,-0.18896601992068227,0.04255405207435462,0.7599973733245824,0.598934426926407,-0.48613310875494586,-0.18896601992068227,0.9708057586304926,0.38007859388666043,0.26883090389803893,0.38007859388666043,6.1027541191014,1.5779570986245492,0.6529098806119115,-0.6075273683129577
3,216
Anion transmembrane transporter activity
20
38
1.986004
0.047033
Q9H2D1,O14745,Q9H9B4,Q02978,P05141,Q6NUK1,Q9Y6M7,P45880,P21796,Q8TB61,Q9BXP2,P53007,Q9UBX3,Q99808,P12236,O43808,Q96NB2,Q15758,O75746,Q9Y277
Functions
GO Molecular function
msigdb_gomf
1,727,296,757,654,619,890,66,65,341,499,326,236,786,584,96,113,373,359,272
891,727,1334,96,359,988,654,1644,1070,584,65,1650,66,326,2704,2758,757,373,1587,619,1381,2722,341,1024,113,3207,2262,786,499,1,2001,296,2174,236,883,272,2744,890
0.4352423338200509,0.5446668824908113,0.15633251874022483,1.6756866487455853,0.9185169053570901,0.38007859388666043,0.598934426926407,-0.014824683336963967,0.32460928917017773,0.6529098806119115,1.9633274991781329,-0.014824683336963967,1.9633274991781329,0.9708057586304926,-0.7924421870337799,-0.854852845001873,0.5446668824908113,0.9185169053570901,0.04255405207435462,0.6529098806119115,0.15633251874022483,-0.7924421870337799,0.9708057586304926,0.38007859388666043,1.62694013996398,-4.621457222623344,-0.36620096012652253,0.5446668824908113,0.7599973733245824,6.1027541191014,-0.18896601992068227,1.0745745880220183,-0.3067719053974511,1.1772838549439275,0.4901039644802168,1.1260602689980173,-0.7924421870337799,0.4901039644802168
3,216
Increased csf lactate
13
44
1.985865
0.047048
Q96CU9,O75380,Q16795,P13073,O75306,O00483,Q99714,Q8NI60,O43678,P49821,O95831,O75489,O43819
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
450,70,72,219,162,241,381,208,21,325,58,398,173
241,21,173,815,162,70,398,1439,58,1443,1161,3020,219,1345,659,1549,1177,1078,1651,2372,429,2042,325,835,836,1269,1189,72,1382,1112,2330,776,208,3050,2406,450,868,1215,381,2565,2174,1048,2933,2516
1.1260602689980173,3.4551147492200505,1.2789556593345546,0.4901039644802168,1.3294092295054736,1.9159521152124348,0.8659545453435412,0.09960517303232037,2.104137155032703,0.09960517303232037,0.26883090389803893,-1.3687923128782735,1.1772838549439275,0.15633251874022483,0.598934426926407,0.04255405207435462,0.26883090389803893,0.32460928917017773,-0.014824683336963967,-0.48613310875494586,0.8131157079420699,-0.24769501940385638,0.9708057586304926,0.4901039644802168,0.4901039644802168,0.21273986061826164,0.26883090389803893,1.9159521152124348,0.15633251874022483,0.32460928917017773,-0.4259865462215386,0.5446668824908113,1.2282480860545921,-1.4349500541120128,-0.48613310875494586,0.8131157079420699,0.4901039644802168,0.26883090389803893,0.9185169053570901,-0.6075273683129577,-0.3067719053974511,0.38007859388666043,-1.1084937197910267,-0.546645177342604
3,216
Dicarboxylic aciduria
9
24
1.962187
0.049741
Q96EY8,O43772,Q92947,P35914,P54098,P23786,P53007,Q4G176,P48735
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
105,5,379,400,47,76,326,93,89
5,470,2029,994,3023,1260,76,400,2213,1458,89,924,2464,326,1269,47,936,695,93,379,105,792,1050,1327
5.247861600040695,0.7599973733245824,-0.24769501940385638,0.38007859388666043,-1.3687923128782735,0.21273986061826164,1.868353764466578,0.8659545453435412,-0.36620096012652253,0.09960517303232037,1.7241989713949182,0.4352423338200509,-0.546645177342604,0.9708057586304926,0.21273986061826164,2.3345548914896983,0.4352423338200509,0.598934426926407,1.7241989713949182,0.9185169053570901,1.6756866487455853,0.5446668824908113,0.38007859388666043,0.21273986061826164
3,216
cytoplasmic
183
425
5.58738
0
P16333,P51114,P04792,O14976,P42766,P63244,P25787,Q9P253,Q9NT62,P50570,O14757,O43301,O95747,P08134,P13807,P55212,Q99460,Q99615,Q99816,P61923,Q9H074,Q9UHB9,P0DP25,Q9NR45,P47756,Q9Y3I0,O15144,O43709,P11413,P28074,Q13614,P46379,P48643,O43237,P51116,P61160,Q15691,O00429,Q92530,Q9Y496,Q9BT73,Q9Y295,Q9UKS6,Q9UL46,Q9NVZ3,O75832,P09132,P10398,P15104,Q9Y6W5,P55036,Q06323,Q03426,P60953,Q99543,Q9UDY2,Q7L2H7,Q86UK7,Q8NB46,Q92538,Q13409,Q9H0U4,Q9H269,Q9ULC3,Q9Y5X3,O95433,Q2NL82,Q9Y6I3,O60684,O95352,Q96B36,O95861,Q8IZ83,P07947,P14550,Q9H0F7,Q8N6T3,Q04917,Q7Z4Q2,Q9Y3A5,Q9NZL4,Q99439,Q9Y4P1,P00966,Q9UBB4,Q96KB5,Q16543,Q00535,O60524,P42566,P19784,P14635,P25098,P49720,Q96GA3,P68371,Q13561,Q9H0A8,Q9Y3P9,Q969U7,Q92973,P25789,O95456,O43175,P49721,Q9BUB5,Q969T9,P84098,P28482,Q96FJ2,P26373,P20618,O75792,O60566,P61020,P14174,Q02750,Q13555,Q16637,P55010,P52732,P50579,Q96EK5,Q96D46,Q16513,Q96F86,O15145,Q96S59,Q99436,Q9BVS4,Q9Y237,Q13596,Q7KZI7,O00231,O00505,O60701,O75821,P06493,P28072,P42574,P78362,P61586,Q15437,P61081,P53367,P40616,P36405,Q9Y547,Q9H7E9,Q86VN1,Q9UQB8,P35998,Q9UNM6,O00233,Q15185,Q13685,P41240,P46777,Q9UHY1,Q9UJX5,P62906,Q13418,P52294,P25788,P55210,P24941,Q15126,Q13907,Q0VDF9,Q8WUX9,Q6P2P2,Q9UBF8,Q9Y6G9,Q99747,P62330,Q07866,O75122,O75165,P12004,P20339,O43414,P50395,P11802
Localization
OpenCell Localization
opencell_localization
487,492,8,478,13,553,22,27,568,549,531,533,536,58,542,67,603,604,71,76,79,618,85,613,585,89,577,579,581,582,95,583,586,91,94,589,592,110,652,131,661,674,669,144,143,623,626,627,631,161,636,151,150,639,177,181,707,708,173,709,700,716,718,722,724,185,202,209,680,682,205,683,203,684,687,223,762,216,758,779,235,770,236,226,776,254,751,247,730,244,242,735,736,246,276,746,270,278,280,827,825,265,261,259,268,831,296,291,288,319,793,790,783,782,805,307,808,810,313,802,801,800,893,891,882,895,333,897,898,900,909,879,375,847,355,356,854,858,360,363,366,875,370,873,869,865,864,433,426,955,432,406,973,393,411,943,921,922,474,475,935,942,929,440,930,439,1009,1008,1006,515,505,1023,528,518,1004,1005,981,982,987,988,480,997,485
1383,2515,847,1091,393,2963,1092,1600,2157,110,1029,355,1518,1030,531,478,1031,577,333,1167,1095,1743,259,91,1672,533,480,1169,1746,579,730,782,1244,680,356,1171,1674,981,982,1098,783,854,623,1812,1678,2289,2937,682,1174,185,261,536,1895,1814,683,2292,1036,1319,226,1466,8,858,2294,1524,1252,2167,684,58,2035,626,2230,1682,2523,85,627,1178,2682,581,485,987,1392,2995,542,307,1181,687,1255,735,631,1256,487,1527,1182,1325,1755,2970,2040,242,2582,2771,988,790,1684,1469,439,736,1110,1260,22,440,265,1042,793,1184,2684,1974,1975,1471,1530,360,582,3068,288,3069,2110,2587,2526,1472,2358,1532,1330,1759,2171,1396,1689,1760,406,1825,864,2173,1190,2174,2426,1475,865,2360,1331,921,1477,3015,1901,2811,244,363,13,1902,1978,1617,583,922,1398,585,586,1114,2300,1828,2362,1048,246,268,1115,997,549,800,1336,1829,1116,492,94,1693,1117,1980,929,801,1761,1195,869,1981,2115,999,1762,1763,2304,802,636,1907,930,67,1982,2305,1267,2534,1543,1480,639,805,873,1403,589,1340,1985,875,76,2429,2921,1547,3035,2478,2308,1054,1341,1004,1405,1911,2179,935,2696,2479,1836,2883,1342,553,746,366,1407,291,247,2370,1485,1343,808,2851,150,216,1768,2885,151,1005,1271,1006,2433,1699,1990,1273,2483,2123,1490,700,942,1345,810,270,879,95,943,1492,1008,1991,2313,2315,1059,2375,1916,1846,2250,2821,1203,1350,1553,1918,1009,411,2062,1774,3001,370,592,1206,2190,882,2130,1208,751,313,202,2700,1998,1850,1135,505,375,707,1282,1355,2197,758,1708,708,955,203,2072,762,173,1138,1287,1428,515,2667,1429,652,709,1430,1360,1070,2389,825,296,827,2140,1503,205,891,3074,893,895,319,276,254,1569,1935,897,898,770,603,177,604,1655,518,71,1571,1076,2011,1869,661,831,900,2714,1657,3196,1222,79,278,1574,223,716,718,1724,1368,1443,426,613,568,2276,143,1950,2336,1663,1664,235,27,776,1952,1023,2338,181,618,474,1587,2022,1882,475,1590,3167,669,144,722,2150,1379,1884,2025,2756,973,432,2215,1954,909,1801,674,2457,1456,779,2153,89,280,131,3194,236,433,1160,1313,724,2221,528,209,161
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3,216
Proteolysis
117
385
5.241343
0
P81605,Q5VTR2,P33908,P62081,Q9NWV8,Q8TDB6,P48147,P63244,Q5TDH0,P25787,Q86UE8,O95155,Q7L5Y9,Q9NZJ0,P35222,P04080,P49773,P49593,P10619,P42575,P35237,P60604,Q13492,Q8NEZ5,P55212,Q96HY6,Q99460,Q99816,Q9UL15,P28074,P46379,Q96KP4,Q99497,Q96DE0,O75150,P17655,P07355,Q92530,Q9BW61,Q9H8M7,Q9UKS6,P42785,Q9UNN5,Q9UL46,O75832,O14967,Q9BWJ5,Q96RU2,P10398,P14735,Q15366,Q06323,P55036,O94782,O14727,P62877,P60520,P55786,Q14999,Q9NXR7,Q6GQQ9,Q86UK7,Q92769,P78559,Q99829,P12931,Q9UPT9,Q96FZ2,Q92820,O14773,Q9NZL4,Q9Y4P1,P13798,Q13867,Q9H7D7,Q96KB5,Q00535,P19784,P49720,Q9HB40,P48506,P25789,P49721,Q9Y3I1,Q9UBW8,Q9BXI6,Q96FW1,Q9GZP4,Q93009,P53634,Q8TBC4,Q7L266,Q86TI2,Q92896,Q9Y5K5,P28072,P42574,Q12765,P52888,Q92990,Q9NY33,Q7Z6J8,P35998,O43765,O75116,P07384,O00233,Q14674,P30086,Q92905,Q9UJX5,P25788,P24941,Q13309,P63208,Q8WUX9,Q9UNE7
Processes and pathways
GO Biological process
msigdb_gobp
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