term
stringlengths
2
121
overlap
int64
6
281
setsize
int64
7
499
score
float64
1.96
10.6
pval
float64
0
0.05
edge
stringlengths
41
1.97k
type
stringclasses
5 values
subtype
stringclasses
24 values
subtype_key
stringclasses
24 values
edge_idxs
stringlengths
11
1.17k
ann_idxs
stringlengths
19
2.31k
ann_vals
stringlengths
124
9.94k
sig_size
int64
2.2k
3.73k
Protein targeting
19
89
2.696617
0.007005
Q8IWJ2,P31751,O60725,Q15041,O60830,Q9UII2,Q99595,Q5JRX3,O95831,Q99797,O43615,O14737,Q9NS69,O43464,Q15785,P55786,P43307,O43681,O00170
Processes and pathways
GO Biological process
msigdb_gobp
262,254,9,273,13,149,24,41,39,45,294,293,53,74,212,100,99,116,121
1449,812,121,1887,1205,293,2181,74,294,116,2128,9,13,1891,443,1852,1038,900,2363,39,728,1219,2291,1990,678,1402,534,1283,1593,254,1228,1527,1147,99,601,909,1233,2281,1152,912,100,2209,1535,1346,1814,311,690,1417,781,1418,742,372,1475,2396,1422,273,1359,790,212,1965,1771,1016,41,752,538,1115,1116,1827,262,1779,1927,660,24,45,714,485,53,1734,1692,522,1566,2146,149,1570,2394,988,1387,491,811
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2,451
Small molecule metabolic process
76
390
2.636931
0.008366
P78417,Q14914,Q9NUJ1,O15382,Q969T7,Q8N4Q0,Q15067,O60725,P14550,P31751,P17812,Q14849,P35914,Q9BWD1,P35270,P41440,Q9H773,P16930,Q86W56,Q9HCC0,Q9UDR5,Q9BV57,P43304,Q9NSE4,P37268,P11413,Q9BYT8,Q8N8N7,Q16850,P34897,Q9H2D1,P06576,Q9UDY2,Q9Y2Z4,Q8WTV0,P25325,O75844,P07099,P34896,Q9H0R6,Q9UJZ1,Q8IWA4,O94788,Q9BQE5,O43808,P30837,P50213,Q9UHB6,Q9UJS0,Q9H7Z7,Q5ST30,Q92947,P00374,Q15120,O60701,O00330,Q8N2K0,P38435,P23786,P23919,Q6PI48,O00116,Q9NP81,Q04760,Q8NFF5,Q9H845,Q9Y3B8,Q96PU8,Q14739,P28288,P23378,A1L0T0,Q9NRN7,P49748,O75947,O43708
Processes and pathways
GO Biological process
msigdb_gobp
2,3,4,5,6,7,132,9,134,254,253,272,267,21,144,23,25,26,286,157,158,30,155,32,281,279,165,37,36,167,42,170,172,173,46,296,48,49,297,187,189,59,182,62,191,192,310,69,198,339,334,336,200,78,323,207,81,328,83,210,213,87,215,91,227,229,230,96,224,220,97,104,109,236,234,244
104,769,87,897,724,207,2180,2308,990,1984,1207,2268,2384,1077,1208,5,1034,1392,1452,2345,244,1511,191,639,586,1210,442,1133,1740,1849,1700,323,9,2380,1574,771,2129,1137,385,48,2201,641,234,940,182,495,527,2204,1331,1576,1214,1396,1515,200,1893,1215,464,1640,1454,1081,496,1332,1703,2417,729,857,994,677,1744,2413,1216,2246,1516,170,1641,1082,49,1517,590,1802,2046,819,1401,591,2068,998,1334,1580,530,2018,2434,1581,1949,999,499,2414,279,2292,1403,1000,1085,2047,1275,679,859,326,406,134,367,1705,500,465,2439,562,2395,643,26,425,253,680,1090,1521,732,466,861,1748,1587,1898,467,1523,97,906,1461,1225,83,210,1642,408,596,296,948,1004,1643,1706,2101,220,863,564,2365,345,1093,192,1410,1143,1708,254,391,1806,1336,1644,1044,297,167,1809,144,267,597,736,2450,2104,1594,281,685,2157,328,737,2207,1468,1095,599,1469,1859,23,950,1096,2019,155,1530,1648,1599,1232,869,2437,2346,2106,1753,1286,1287,2347,236,1413,2281,2282,686,871,1234,310,2183,2381,604,427,2072,605,829,830,470,2348,1048,1343,1758,535,873,1759,1290,740,1344,1534,1102,1158,1235,1715,2410,1904,959,1292,2,1958,2107,1419,1718,2294,2108,649,1237,91,1013,1162,651,2184,2431,372,2382,2386,415,2313,1111,698,1866,876,2026,1015,224,272,3,449,2139,132,78,396,2447,2353,792,1113,1612,1483,615,450,36,704,1613,451,2236,569,616,334,431,1614,1554,1431,1305,213,751,511,1618,1173,433,286,59,1118,1486,81,7,37,434,2117,227,883,1176,1309,46,658,884,336,2060,6,1313,543,1021,1782,96,2373,1877,1441,2174,1370,2359,1178,62,2120,574,545,2335,1373,2448,30,759,418,21,1733,663,165,2193,187,42,1686,25,339,229,1183,1787,2409,2289,157,215,457,1627,1500,520,109,1378,32,4,667,1027,2390,380,1261,1189,1936,1792,2224,158,172,69,2147,198,189,1567,2340,2228,2179,1030,173,1198,2319,230,985,987,1389,768
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2,451
Transporter
37
146
2.58349
0.009781
P37198,P20020,O75746,Q6NT16,P08183,O95202,Q6NUK1,P41440,O15439,P51809,P24539,P12235,O75027,Q8IXU6,Q9H2D1,P06576,O60645,P08195,Q9BQE5,O43808,Q9UJS0,Q8N1F7,O60664,Q9BSK2,P53985,O95721,Q70HW3,Q96AX1,P28288,P30040,P24390,Q8WUX9,O43772,O00400,O75947,Q92572,P05026
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
135,389,385,17,18,265,285,23,151,282,408,405,276,38,42,170,295,175,62,191,198,77,208,82,90,93,226,363,220,353,105,239,232,112,234,247,366
1797,1887,112,1508,2066,2242,1205,1328,151,1739,232,191,295,208,1134,1636,276,1268,385,234,423,265,901,818,2429,93,728,1745,366,1578,170,18,175,2392,405,1221,1897,946,389,1405,905,1225,105,408,948,220,353,1529,736,135,737,23,951,1860,909,603,912,282,1153,1100,1713,1651,90,2053,1289,832,411,688,1344,1102,1714,447,1814,1009,1605,1542,1816,1763,609,448,2342,1161,2304,963,1353,964,1298,1820,1358,613,1359,703,1428,17,285,1305,226,1115,539,38,77,1487,1176,1780,477,239,708,247,659,2253,363,1874,1317,1679,660,628,62,1681,82,805,1683,1882,1180,42,2040,1183,2289,1126,1072,1127,2254,2361,2064,1504,2224,1505,720,198,2196,2264,1028,1981,809,768,1571,523
-0.3786655961593971,-0.4398329878954713,1.359227380748379,-0.22741793501362412,-0.5944992697412328,-0.815463659775052,-0.0784557007759784,-0.1377740898892939,1.1494772064741625,-0.34822722873979567,0.8277550450555999,0.9359825972271626,0.6910167868939782,0.8819955449514524,-0.04892699603974394,-0.28763581239975017,0.7184965916047329,-0.10807109727927224,0.524705739682176,0.8277550450555999,0.46870852015967773,0.7459097574001678,0.09744671117039397,0.15541928815000872,-2.528431000652648,1.4885192775711327,0.21307185932672598,-0.34822722873979567,0.5525977560753771,-0.257480688132458,1.016496960173559,4.147422713743819,0.9897203299451159,-1.5136596600643046,0.49674287398114536,-0.0784557007759784,-0.4398329878954713,0.0683384434312082,0.524705739682176,-0.16756559926044762,0.09744671117039397,-0.0784557007759784,1.4369643345051797,0.49674287398114536,0.0683384434312082,0.8549072385416738,0.5804195522374354,-0.22741793501362412,0.21307185932672598,1.2285598984577069,0.21307185932672598,3.425644227114312,0.0683384434312082,-0.40920048646832796,0.09744671117039397,0.29896409097336984,0.09744671117039397,0.7184965916047329,-0.04892699603974394,-0.019484094638846886,-0.3178843166402954,-0.28763581239975017,1.514217019711359,-0.5633616250295993,-0.10807109727927224,0.15541928815000872,0.49674287398114536,0.24178007074161137,-0.1377740898892939,-0.019484094638846886,-0.3178843166402954,0.4406020294542778,-0.3786655961593971,0.039147774693997224,-0.257480688132458,-0.22741793501362412,-0.3786655961593971,-0.34822722873979567,0.29896409097336984,0.4406020294542778,-1.1409505733515366,-0.04892699603974394,-0.9766874655426719,0.0683384434312082,-0.1377740898892939,0.0683384434312082,-0.10807109727927224,-0.3786655961593971,-0.1377740898892939,0.29896409097336984,-0.1377740898892939,0.24178007074161137,-0.16756559926044762,4.211472069811639,0.7184965916047329,-0.10807109727927224,0.8549072385416738,-0.019484094638846886,0.3558430944471442,2.621213590195934,1.6673111019721019,-0.19744656278221268,-0.04892699603974394,-0.34822722873979567,0.412422742929421,0.8277550450555999,0.24178007074161137,0.8005384298975836,0.2704105689905207,-0.815463659775052,0.5804195522374354,-0.40920048646832796,-0.10807109727927224,-0.28763581239975017,0.2704105689905207,0.29896409097336984,1.8686241919102264,-0.28763581239975017,1.6164853429596542,0.1842851856536623,-0.28763581239975017,-0.40920048646832796,-0.04892699603974394,2.5501516672317077,-0.5323273632124869,-0.04892699603974394,-0.9118443106940877,-0.019484094638846886,0.00987387634422139,-0.019484094638846886,-0.815463659775052,-1.2410510014930003,-0.5633616250295993,-0.19744656278221268,-0.751782004665589,-0.19744656278221268,0.24178007074161137,0.9359825972271626,-0.7201085576537448,-0.8474746725329925,0.039147774693997224,-0.4705642099006684,0.1842851856536623,0.21307185932672598,-0.22741793501362412,0.38416999124999995
2,451
Abnormal blood glucose concentration
24
76
2.534659
0.011256
Q14738,Q00059,P31751,P83436,Q8N183,P16930,Q9HCC0,Q9Y375,Q9NSE4,O75844,O43676,Q9H0R6,Q9NPL8,Q4J6C6,O00330,P22695,P23786,P53985,Q9H845,Q8IUX1,P49748,O43772,Q9P032,P49419
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
131,257,254,256,141,26,157,159,32,48,174,187,188,71,207,209,83,90,229,101,236,232,120,123
207,174,232,494,402,1394,48,641,2015,1331,1515,942,2246,1516,997,1334,2414,2292,679,562,26,445,209,83,596,1525,254,1006,267,2104,685,2207,599,950,468,123,236,1813,427,777,90,1758,1290,471,256,257,1768,131,792,450,1613,2236,71,1061,1485,657,101,141,2399,336,2373,1370,2219,1024,187,229,157,188,1378,32,1185,120,420,159,1385,421
0.8819955449514524,0.9897203299451159,0.8277550450555999,0.38416999124999995,0.49674287398114536,-0.16756559926044762,2.310642065567253,0.2704105689905207,-0.5323273632124869,-0.1377740898892939,-0.22741793501362412,0.0683384434312082,-0.815463659775052,-0.22741793501362412,0.039147774693997224,-0.1377740898892939,-1.8655830315992803,-0.9442059292838775,0.24178007074161137,0.3274413616771643,3.20020104613835,0.4406020294542778,0.8819955449514524,1.5909959114922732,0.29896409097336984,-0.22741793501362412,0.7732568507472157,0.039147774693997224,0.7459097574001678,-0.6257415222865993,0.24178007074161137,-0.751782004665589,0.29896409097336984,0.0683384434312082,0.412422742929421,1.2809952793799848,0.8277550450555999,-0.3786655961593971,0.46870852015967773,0.1842851856536623,1.514217019711359,-0.34822722873979567,-0.10807109727927224,0.412422742929421,0.7732568507472157,0.7732568507472157,-0.34822722873979567,1.25480593816419,0.1842851856536623,0.4406020294542778,-0.257480688132458,-0.7835665762622805,1.7431723198248983,0.00987387634422139,-0.19744656278221268,0.2704105689905207,1.4627685117962506,1.2022567249634681,-1.5830700950355348,0.6358549527434101,-1.3084367659564569,-0.1377740898892939,-0.751782004665589,0.039147774693997224,0.9628823750360523,0.8549072385416738,1.1229999616061817,0.9628823750360523,-0.1377740898892939,2.832301970314483,-0.04892699603974394,1.3071283517404273,0.49674287398114536,1.1229999616061817,-0.1377740898892939,0.49674287398114536
2,451
Increased serum lactate
32
84
2.532351
0.01133
P13073,Q8N183,P35914,Q9BW92,Q9BWD1,Q7L0Y3,Q9Y6M9,Q9Y375,P12235,O75306,P82650,Q5JRX3,O95831,Q5T160,Q99797,Q9Y2Z4,O75439,O43464,P19404,O00330,P36776,P22695,Q6PI48,Q9H845,P42704,Q70HW3,Q8IUX1,O75648,P82673,P82930,Q96RP9,P20674
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
388,141,267,418,21,417,421,159,405,402,163,41,39,431,45,173,443,74,445,207,327,209,213,229,468,226,101,218,471,472,518,122
207,989,1204,725,74,494,402,443,1394,218,2015,642,39,1396,1215,1454,997,591,944,1896,1334,2292,405,388,445,122,861,209,596,1525,863,1410,267,327,1095,468,2352,953,1813,2072,775,777,1343,1758,163,471,472,1816,649,694,2139,615,1613,1771,1016,41,616,431,1061,1431,213,226,417,657,101,141,2117,976,801,518,1370,45,2009,418,21,1024,229,716,718,2224,173,159,2391,421
0.8819955449514524,0.039147774693997224,-0.0784557007759784,0.21307185932672598,1.6673111019721019,0.38416999124999995,0.49674287398114536,0.4406020294542778,-0.16756559926044762,0.8549072385416738,-0.5323273632124869,0.2704105689905207,2.57387865209091,-0.16756559926044762,-0.0784557007759784,-0.19744656278221268,0.039147774693997224,0.29896409097336984,0.0683384434312082,-0.4398329878954713,-0.1377740898892939,-0.9442059292838775,0.49674287398114536,0.524705739682176,0.4406020294542778,1.2809952793799848,0.12647339246637346,0.8819955449514524,0.29896409097336984,-0.22741793501362412,0.12647339246637346,-0.16756559926044762,0.7459097574001678,0.6358549527434101,-0.019484094638846886,0.412422742929421,-1.2075530729273112,0.0683384434312082,-0.3786655961593971,-0.5944992697412328,0.1842851856536623,0.1842851856536623,-0.1377740898892939,-0.34822722873979567,1.0698682053374946,0.412422742929421,0.412422742929421,-0.3786655961593971,0.2704105689905207,0.24178007074161137,-0.6570896327307384,0.29896409097336984,-0.257480688132458,-0.34822722873979567,0.039147774693997224,2.57387865209091,0.29896409097336984,0.46870852015967773,0.00987387634422139,-0.16756559926044762,0.8819955449514524,0.8549072385416738,0.49674287398114536,0.2704105689905207,1.4627685117962506,1.2022567249634681,-0.6257415222865993,0.0683384434312082,0.1842851856536623,0.38416999124999995,-0.1377740898892939,2.4309120584409074,-0.5013952837666465,0.49674287398114536,3.581513700189797,0.039147774693997224,0.8549072385416738,0.24178007074161137,0.24178007074161137,-0.751782004665589,1.016496960173559,1.1229999616061817,-1.4791407275236588,0.49674287398114536
2,451
Abnormal circulating carboxylic acid concentration
19
76
2.494698
0.012606
O15382,P35270,P41440,P16930,Q9HCC0,Q9UDR5,P37268,Q9UDY2,Q99797,Q9UJS0,O00330,P22695,P23786,Q14739,Q8IUX1,P28288,O75648,P23378,P20674
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
5,144,23,26,157,158,281,172,45,198,207,209,83,224,101,220,218,97,122
207,5,1034,218,2015,1577,1081,729,2413,2246,1516,2046,819,591,1896,1334,730,279,2292,679,1141,26,1521,122,209,97,1461,83,948,220,144,866,281,1231,685,1468,23,2019,2106,2162,829,777,740,1346,1765,1995,224,2139,792,1613,451,2236,1061,1772,417,1173,1917,101,336,543,2373,2174,45,1180,1497,1787,157,1378,1189,158,172,522,198,1939,1389,768
0.8819955449514524,6.375134995207417,0.00987387634422139,0.8549072385416738,-0.5323273632124869,-0.257480688132458,-0.019484094638846886,0.21307185932672598,-1.8655830315992803,-0.815463659775052,-0.22741793501362412,-0.5633616250295993,0.15541928815000872,0.29896409097336984,-0.4398329878954713,-0.1377740898892939,0.21307185932672598,0.7184965916047329,-0.9442059292838775,0.24178007074161137,-0.04892699603974394,3.20020104613835,-0.22741793501362412,1.2809952793799848,0.8819955449514524,1.4627685117962506,-0.19744656278221268,1.5909959114922732,0.0683384434312082,0.8549072385416738,1.1758959766163357,0.12647339246637346,0.7184965916047329,-0.0784557007759784,0.24178007074161137,-0.19744656278221268,3.425644227114312,-0.5323273632124869,-0.6257415222865993,-0.6885448770013346,0.15541928815000872,0.1842851856536623,0.21307185932672598,-0.1377740898892939,-0.34822722873979567,-0.5013952837666465,0.8549072385416738,-0.6570896327307384,0.1842851856536623,-0.257480688132458,0.4406020294542778,-0.7835665762622805,0.00987387634422139,-0.34822722873979567,0.49674287398114536,-0.04892699603974394,-0.4398329878954713,1.4627685117962506,0.6358549527434101,0.3558430944471442,-1.3084367659564569,-0.6885448770013346,2.4309120584409074,-0.04892699603974394,-0.19744656278221268,-0.34822722873979567,1.1229999616061817,-0.1377740898892939,-0.04892699603974394,1.1229999616061817,1.016496960173559,0.38416999124999995,0.9359825972271626,-0.4398329878954713,-0.1377740898892939,0.21307185932672598
2,451
Cell cell junction
11
85
2.348168
0.018866
Q9NR77,Q9UQB8,Q13177,Q16625,Q13112,Q9UDY2,Q99797,Q9Y2S7,Q92692,P41440,Q9NYL9
Localization
GO Cellular component
msigdb_gocc
0,1,66,154,76,172,45,181,147,23,127
1032,937,1942,1270,1892,2417,366,2413,528,1947,1274,1804,2100,1276,2050,1586,2155,1749,1463,1284,1528,1337,1146,1466,565,644,23,1649,2341,2163,2164,1103,1536,2210,1715,959,413,647,177,1865,1658,1659,507,1475,76,66,697,332,1300,876,1301,919,791,1427,154,1362,1823,315,1825,2002,841,1621,147,799,2004,802,625,1624,1441,45,1835,1930,2420,0,127,1379,1127,172,1565,1569,1,181,1982,636,637
0.00987387634422139,0.0683384434312082,-0.4705642099006684,-0.10807109727927224,-0.4398329878954713,-1.9374039400839855,0.5525977560753771,-1.8655830315992803,0.3558430944471442,-0.4705642099006684,-0.10807109727927224,-0.3786655961593971,-0.6257415222865993,-0.10807109727927224,-0.5633616250295993,-0.257480688132458,-0.6885448770013346,-0.34822722873979567,-0.19744656278221268,-0.10807109727927224,-0.22741793501362412,-0.1377740898892939,-0.04892699603974394,-0.19744656278221268,0.3274413616771643,0.2704105689905207,3.425644227114312,-0.28763581239975017,-1.1409505733515366,-0.6885448770013346,-0.6885448770013346,-0.019484094638846886,-0.22741793501362412,-0.751782004665589,-0.3178843166402954,0.0683384434312082,0.49674287398114536,0.2704105689905207,0.9897203299451159,-0.40920048646832796,-0.28763581239975017,-0.28763581239975017,0.38416999124999995,-0.19744656278221268,1.6673111019721019,1.8185889485528128,0.24178007074161137,0.6358549527434101,-0.10807109727927224,0.12647339246637346,-0.10807109727927224,0.09744671117039397,0.1842851856536623,-0.16756559926044762,1.1494772064741625,-0.1377740898892939,-0.3786655961593971,0.6634697684133223,-0.3786655961593971,-0.5013952837666465,0.15541928815000872,-0.257480688132458,1.1758959766163357,0.1842851856536623,-0.5013952837666465,0.1842851856536623,0.29896409097336984,-0.257480688132458,-0.16756559926044762,2.4309120584409074,-0.3786655961593971,-0.4398329878954713,-2.1189915114141065,8.08208815617794,1.2809952793799848,-0.1377740898892939,-0.019484094638846886,1.016496960173559,-0.22741793501362412,-0.22741793501362412,7.641208038841144,0.9897203299451159,-0.4705642099006684,0.29896409097336984,0.29896409097336984
2,451
Sensorimotor neuropathy
6
24
2.296396
0.021653
Q9NR77,Q9NSE4,O95831,Q15120,Q8N2K0,P41440
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
0,32,39,78,81,23
989,442,39,1215,1745,2045,731,1461,130,599,23,954,830,1759,1290,373,78,81,1019,0,32,1072,635,810
0.039147774693997224,0.4406020294542778,2.57387865209091,-0.0784557007759784,-0.34822722873979567,-0.5633616250295993,0.21307185932672598,-0.19744656278221268,1.25480593816419,0.29896409097336984,3.425644227114312,0.0683384434312082,0.15541928815000872,-0.34822722873979567,-0.10807109727927224,0.5525977560753771,1.6419236197042295,1.6164853429596542,0.039147774693997224,8.08208815617794,2.832301970314483,0.00987387634422139,0.29896409097336984,0.1842851856536623
2,451
Abnormality of the cerebrospinal fluid
36
109
2.25827
0.023929
Q9NR77,O75251,Q14738,P08236,O15382,P13073,P07237,Q8N183,O95202,Q6NUK1,Q7L0Y3,Q9Y6M9,Q16625,Q9Y375,O75306,O95831,Q5T160,O43676,Q9NPL8,O14802,O43464,P19404,Q92947,O00330,P36776,P23786,Q6PI48,P42704,Q8IUX1,Q96AX1,P48651,P82930,O43681,Q96RP9,Q9P032,Q10713
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
0,494,131,498,5,388,387,141,265,285,417,421,154,159,402,39,431,174,188,440,74,445,336,207,327,83,213,468,101,363,222,472,116,518,120,372
207,1204,440,5,74,2182,174,116,2320,494,402,1394,1212,900,265,642,39,2290,1215,1332,677,387,498,591,1582,388,643,1003,445,1855,1335,2155,1406,83,2231,1525,863,1526,1410,1336,1337,1645,327,2157,1095,468,222,1413,1812,1813,2072,777,778,2053,688,1049,472,1764,1765,649,1051,1052,783,372,1108,610,1357,131,2139,2447,1060,154,615,431,285,213,417,657,972,101,141,1249,2117,976,2273,336,2060,542,363,2035,518,2037,1370,2009,1258,1497,2289,188,0,1789,1260,1185,1072,120,1936,2265,159,987,421
0.8819955449514524,-0.0784557007759784,0.4406020294542778,6.375134995207417,1.6673111019721019,-0.7201085576537448,0.9897203299451159,1.3071283517404273,-1.0420166552866306,0.38416999124999995,0.49674287398114536,-0.16756559926044762,-0.0784557007759784,0.09744671117039397,0.7459097574001678,0.2704105689905207,2.57387865209091,-0.9442059292838775,-0.0784557007759784,-0.1377740898892939,0.24178007074161137,0.524705739682176,0.38416999124999995,0.29896409097336984,-0.257480688132458,0.524705739682176,0.2704105689905207,0.039147774693997224,0.4406020294542778,-0.40920048646832796,-0.1377740898892939,-0.6885448770013346,-0.16756559926044762,1.5909959114922732,-0.7835665762622805,-0.22741793501362412,0.12647339246637346,-0.22741793501362412,-0.16756559926044762,-0.1377740898892939,-0.1377740898892939,-0.28763581239975017,0.6358549527434101,-0.6885448770013346,-0.019484094638846886,0.412422742929421,0.8549072385416738,-0.16756559926044762,-0.3786655961593971,-0.3786655961593971,-0.5944992697412328,0.1842851856536623,0.1842851856536623,-0.5633616250295993,0.24178007074161137,0.00987387634422139,0.412422742929421,-0.34822722873979567,-0.34822722873979567,0.2704105689905207,0.00987387634422139,0.00987387634422139,0.1842851856536623,0.5525977560753771,-0.019484094638846886,0.29896409097336984,-0.1377740898892939,1.25480593816419,-0.6570896327307384,-3.7101286452620776,0.00987387634422139,1.1494772064741625,0.29896409097336984,0.46870852015967773,0.7184965916047329,0.8819955449514524,0.49674287398114536,0.2704105689905207,0.0683384434312082,1.4627685117962506,1.2022567249634681,-0.0784557007759784,-0.6257415222865993,0.0683384434312082,-0.8796010627908111,0.6358549527434101,-0.5633616250295993,0.3558430944471442,0.5804195522374354,-0.5323273632124869,0.38416999124999995,-0.5323273632124869,-0.1377740898892939,-0.5013952837666465,-0.0784557007759784,-0.19744656278221268,-0.9118443106940877,0.9628823750360523,8.08208815617794,-0.34822722873979567,-0.0784557007759784,-0.04892699603974394,0.00987387634422139,1.3071283517404273,-0.4398329878954713,-0.8474746725329925,1.1229999616061817,0.0683384434312082,0.49674287398114536
2,451
Ion transmembrane transport
37
121
2.24025
0.025075
Q93034,P78417,P30626,P20020,P13073,Q15041,O75746,P08183,O95202,P41440,O15439,P24539,P17612,P11413,P12235,O75027,Q9H2D1,P06576,Q9UM00,O75844,Q9UHG3,P08195,P31930,Q9UJZ1,O43808,Q8N4V1,Q9UJS0,O75439,P61421,Q96HE7,P53985,Q70HW3,O43772,O00400,O75947,P05026,P20674
Processes and pathways
GO Biological process
msigdb_gobp
399,2,390,389,388,273,385,18,265,23,151,408,407,279,405,276,42,170,305,48,180,175,426,189,191,67,198,443,447,347,90,226,232,112,234,366,122
1983,112,1204,1848,151,1453,232,191,586,1987,2428,276,1942,494,443,385,48,1944,234,940,265,1215,1745,366,2413,1578,528,170,1947,1333,1518,18,175,944,1948,279,405,1221,388,1897,407,389,122,1405,905,2155,466,1225,408,948,1283,1592,390,426,736,1230,737,23,2312,2051,2105,1232,911,2407,90,832,688,1344,1102,447,1814,690,2,1816,742,448,1865,1474,1659,1475,1768,917,1478,1057,1962,273,613,703,840,226,1308,2343,67,1176,399,347,2334,1441,1068,2403,2009,2274,1836,1882,42,2040,1183,2289,761,2224,1381,2146,180,1505,198,189,305,1029,988,810,768
-0.5013952837666465,1.359227380748379,-0.0784557007759784,-0.40920048646832796,1.1494772064741625,-0.19744656278221268,0.8277550450555999,0.9359825972271626,0.29896409097336984,-0.5013952837666465,-2.528431000652648,0.7184965916047329,-0.4705642099006684,0.38416999124999995,0.4406020294542778,0.524705739682176,2.310642065567253,-0.4705642099006684,0.8277550450555999,0.0683384434312082,0.7459097574001678,-0.0784557007759784,-0.34822722873979567,0.5525977560753771,-1.8655830315992803,-0.257480688132458,0.3558430944471442,1.016496960173559,-0.4705642099006684,-0.1377740898892939,-0.22741793501362412,4.147422713743819,0.9897203299451159,0.0683384434312082,-0.4705642099006684,0.7184965916047329,0.49674287398114536,-0.0784557007759784,0.524705739682176,-0.4398329878954713,0.49674287398114536,0.524705739682176,1.2809952793799848,-0.16756559926044762,0.09744671117039397,-0.6885448770013346,0.412422742929421,-0.0784557007759784,0.49674287398114536,0.0683384434312082,-0.10807109727927224,-0.257480688132458,0.524705739682176,0.46870852015967773,0.21307185932672598,-0.0784557007759784,0.21307185932672598,3.425644227114312,-1.0092905014838178,-0.5633616250295993,-0.6257415222865993,-0.0784557007759784,0.09744671117039397,-1.7587385123710009,1.514217019711359,0.15541928815000872,0.24178007074161137,-0.1377740898892939,-0.019484094638846886,0.4406020294542778,-0.3786655961593971,0.24178007074161137,7.587705668152999,-0.3786655961593971,0.21307185932672598,0.4406020294542778,-0.40920048646832796,-0.19744656278221268,-0.28763581239975017,-0.19744656278221268,-0.34822722873979567,0.09744671117039397,-0.19744656278221268,0.00987387634422139,-0.4705642099006684,0.7459097574001678,0.29896409097336984,0.24178007074161137,0.15541928815000872,0.8549072385416738,-0.10807109727927224,-1.1409505733515366,1.8185889485528128,-0.04892699603974394,0.524705739682176,0.6081717477181001,-1.0748675824795813,-0.16756559926044762,0.00987387634422139,-1.652972814945418,-0.5013952837666465,-0.8796010627908111,-0.3786655961593971,-0.40920048646832796,2.5501516672317077,-0.5323273632124869,-0.04892699603974394,-0.9118443106940877,0.21307185932672598,-0.751782004665589,-0.1377740898892939,-0.6570896327307384,0.9897203299451159,-0.19744656278221268,0.9359825972271626,0.9628823750360523,0.6910167868939782,0.039147774693997224,0.0683384434312082,0.1842851856536623,0.21307185932672598
2,451
transporter
11
49
2.236807
0.025299
Q9NR77,Q9UI26,P37198,Q567V2,Q9H2D1,Q8N1F7,O60830,O43681,P41440,Q99595,P53985
Functions
Panther Protein class
panther_protein_class
0,64,135,10,42,77,13,116,23,24,90
1507,2066,2242,1205,899,556,294,116,232,13,1943,2203,865,135,23,1860,2270,1153,1100,1154,90,1289,646,1714,1814,1542,963,1358,10,1115,77,1487,1780,477,659,1874,1367,628,24,1681,1683,42,340,1126,0,64,720,189,768
-0.22741793501362412,-0.5944992697412328,-0.815463659775052,-0.0784557007759784,0.09744671117039397,0.3274413616771643,0.6910167868939782,1.3071283517404273,0.8277550450555999,4.6945921414418414,-0.4705642099006684,-0.751782004665589,0.12647339246637346,1.2285598984577069,3.425644227114312,-0.40920048646832796,-0.8796010627908111,-0.04892699603974394,-0.019484094638846886,-0.04892699603974394,1.514217019711359,-0.10807109727927224,0.2704105689905207,-0.3178843166402954,-0.3786655961593971,-0.22741793501362412,0.0683384434312082,-0.1377740898892939,5.563649503172797,-0.019484094638846886,1.6673111019721019,-0.19744656278221268,-0.34822722873979567,0.412422742929421,0.2704105689905207,-0.40920048646832796,-0.1377740898892939,0.29896409097336984,3.2455574249475116,-0.28763581239975017,-0.28763581239975017,2.5501516672317077,0.6358549527434101,-0.019484094638846886,8.08208815617794,1.8436306014864579,0.24178007074161137,0.9628823750360523,0.21307185932672598
2,451
Primary mitochondrial disease
40
70
2.230286
0.025728
O75251,Q00059,P13073,Q8N183,Q9BW92,O75879,Q7L0Y3,Q9Y2R9,Q9Y6M9,Q9Y375,P12235,O75306,P82650,O95831,Q99797,Q6DKK2,Q9Y2Z4,O43676,Q9H0R6,Q9Y3D9,Q9NPL8,O60313,P19404,Q5ST30,Q5JTZ9,Q16795,P22695,Q96IX5,Q8NFF5,Q9H845,P42704,Q9Y2R0,Q70HW3,Q8IUX1,P82930,P08559,Q96RP9,Q9P032,Q86Y39,P20674
Drugs and Diseases
Protein Atlas Disease involvement
protein_atlas_disease_involvement
494,257,388,141,418,641,417,420,421,159,405,402,163,39,45,178,173,174,187,583,188,442,445,334,616,615,209,348,227,229,468,635,226,101,472,591,518,120,657,122
1204,725,174,442,494,402,1394,641,2015,642,39,1215,591,944,1896,405,388,445,122,209,948,1525,1410,468,2352,953,1813,775,777,163,472,257,694,615,1613,1016,616,334,1061,178,226,417,657,101,141,227,976,801,348,518,45,1371,2009,418,187,229,716,188,1185,120,1189,2224,635,420,173,159,1385,583,2391,421
-0.0784557007759784,0.21307185932672598,0.9897203299451159,0.4406020294542778,0.38416999124999995,0.49674287398114536,-0.16756559926044762,0.2704105689905207,-0.5323273632124869,0.2704105689905207,2.57387865209091,-0.0784557007759784,0.29896409097336984,0.0683384434312082,-0.4398329878954713,0.49674287398114536,0.524705739682176,0.4406020294542778,1.2809952793799848,0.8819955449514524,0.0683384434312082,-0.22741793501362412,-0.16756559926044762,0.412422742929421,-1.2075530729273112,0.0683384434312082,-0.3786655961593971,0.1842851856536623,0.1842851856536623,1.0698682053374946,0.412422742929421,0.7732568507472157,0.24178007074161137,0.29896409097336984,-0.257480688132458,0.039147774693997224,0.29896409097336984,0.6358549527434101,0.00987387634422139,0.9897203299451159,0.8549072385416738,0.49674287398114536,0.2704105689905207,1.4627685117962506,1.2022567249634681,0.8549072385416738,0.0683384434312082,0.1842851856536623,0.6081717477181001,0.38416999124999995,2.4309120584409074,-0.1377740898892939,-0.5013952837666465,0.49674287398114536,0.9628823750360523,0.8549072385416738,0.24178007074161137,0.9628823750360523,-0.04892699603974394,1.3071283517404273,-0.04892699603974394,-0.751782004665589,0.29896409097336984,0.49674287398114536,1.016496960173559,1.1229999616061817,-0.1377740898892939,0.3274413616771643,-1.4791407275236588,0.49674287398114536
2,451
Mitochondrial transport
20
71
2.221169
0.026339
O60830,Q14849,Q9UII2,Q6NUK1,Q99595,Q5JRX3,O95831,P06576,Q99797,O43615,Q9NS69,Q9UJZ1,Q9UJS0,O43464,P23786,Q15785,P55786,O43772,O75947,O00170
Processes and pathways
GO Biological process
msigdb_gobp
13,272,149,285,24,41,39,170,45,294,53,189,198,74,83,212,100,232,234,121
812,121,293,2181,74,294,232,13,1037,443,234,940,1038,900,2363,39,728,677,1578,170,1219,998,678,405,83,408,948,1592,2365,1527,736,1096,2051,1232,909,2281,2282,912,2348,100,1344,1102,1418,372,272,1359,212,1771,1016,41,285,1827,2306,454,1779,924,1317,24,45,714,485,53,1734,1692,2224,149,198,189,2394,1387,491
0.15541928815000872,1.2809952793799848,0.6910167868939782,-0.7201085576537448,1.6673111019721019,0.6910167868939782,0.8277550450555999,4.6945921414418414,0.00987387634422139,0.4406020294542778,0.8277550450555999,0.0683384434312082,0.00987387634422139,0.09744671117039397,-1.274679154319205,2.57387865209091,0.21307185932672598,0.24178007074161137,-0.257480688132458,1.016496960173559,-0.0784557007759784,0.039147774693997224,0.24178007074161137,0.49674287398114536,1.5909959114922732,0.49674287398114536,0.0683384434312082,-0.257480688132458,-1.274679154319205,-0.22741793501362412,0.21307185932672598,-0.019484094638846886,-0.5633616250295993,-0.0784557007759784,0.09744671117039397,-0.9118443106940877,-0.9118443106940877,0.09744671117039397,-1.174186146206551,1.4627685117962506,-0.1377740898892939,-0.019484094638846886,-0.16756559926044762,0.5525977560753771,0.7459097574001678,-0.1377740898892939,0.8819955449514524,-0.34822722873979567,0.039147774693997224,2.57387865209091,0.7184965916047329,-0.3786655961593971,-0.9766874655426719,0.4406020294542778,-0.34822722873979567,0.09744671117039397,-0.10807109727927224,3.2455574249475116,2.4309120584409074,0.24178007074161137,0.412422742929421,2.017594295286358,-0.3178843166402954,-0.28763581239975017,-0.751782004665589,1.1758959766163357,0.9359825972271626,0.9628823750360523,-1.5136596600643046,-0.1377740898892939,0.412422742929421
2,451
Abnormality of the mitochondrion
31
77
2.200168
0.027795
P13073,Q8N183,P82663,P35914,P35637,Q9Y6M9,Q9Y375,P12235,O75306,O43676,Q9H0R6,Q9NPL8,Q4G0N4,Q16836,Q4J6C6,P19404,Q13501,O00330,P23786,Q9H845,P42704,Q70HW3,Q8IUX1,O75648,P49748,O43772,Q96RP9,Q96EY7,Q9P032,P11177,P20674
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
388,141,15,267,145,421,159,405,402,174,187,188,451,450,71,445,331,207,83,229,468,226,101,218,236,232,518,248,120,499,122
207,989,1204,174,232,494,402,1394,218,2015,642,1215,591,1334,1581,499,2414,405,388,679,445,122,861,83,2231,1525,863,1410,145,267,685,599,468,2352,236,1813,775,777,535,1759,15,1816,745,331,2139,792,615,450,1613,1771,451,71,1431,226,2252,1917,657,101,141,976,801,248,518,1370,2009,187,229,188,1185,120,1189,2224,635,159,583,810,421
0.8819955449514524,0.039147774693997224,-0.0784557007759784,0.9897203299451159,0.8277550450555999,0.38416999124999995,0.49674287398114536,-0.16756559926044762,0.8549072385416738,-0.5323273632124869,0.2704105689905207,-0.0784557007759784,0.29896409097336984,-0.1377740898892939,-0.257480688132458,0.38416999124999995,-1.8655830315992803,0.49674287398114536,0.524705739682176,0.24178007074161137,0.4406020294542778,1.2809952793799848,0.12647339246637346,1.5909959114922732,-0.7835665762622805,-0.22741793501362412,0.12647339246637346,-0.16756559926044762,1.1758959766163357,0.7459097574001678,0.24178007074161137,0.29896409097336984,0.412422742929421,-1.2075530729273112,0.8277550450555999,-0.3786655961593971,0.1842851856536623,0.1842851856536623,0.3558430944471442,-0.34822722873979567,4.317676785197601,-0.3786655961593971,0.21307185932672598,0.6358549527434101,-0.6570896327307384,0.1842851856536623,0.29896409097336984,0.4406020294542778,-0.257480688132458,-0.34822722873979567,0.4406020294542778,1.7431723198248983,-0.16756559926044762,0.8549072385416738,-0.815463659775052,-0.4398329878954713,0.2704105689905207,1.4627685117962506,1.2022567249634681,0.0683384434312082,0.1842851856536623,0.8005384298975836,0.38416999124999995,-0.1377740898892939,-0.5013952837666465,0.9628823750360523,0.8549072385416738,0.9628823750360523,-0.04892699603974394,1.3071283517404273,-0.04892699603974394,-0.751782004665589,0.29896409097336984,1.1229999616061817,0.3274413616771643,0.1842851856536623,0.49674287398114536
2,451
Abnormal pyramidal sign
13
104
2.185995
0.028816
Q9NR77,Q15067,P35251,O15382,P37198,O95831,P34897,Q8N2K0,O00400,P35637,O43681,Q9NZ08,P41440
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
0,132,130,5,135,39,167,81,112,145,116,86,23
112,989,1204,2125,1889,440,5,116,442,1740,323,276,494,402,1212,495,900,39,1894,2045,1333,1802,998,1581,678,1458,1705,2364,946,1003,1855,1335,861,2231,1643,1525,1410,1593,167,130,145,135,1095,599,23,2312,1811,1650,1753,1287,686,912,2072,2162,605,2324,1756,873,1759,1290,1049,957,1164,745,373,331,2139,132,1823,1616,178,213,1917,1557,1671,81,884,1019,2033,621,1313,624,1876,2446,2009,2194,1024,1444,1787,0,1934,668,551,2222,86,1072,669,1565,2146,983,2179,987,810,768
1.359227380748379,0.039147774693997224,-0.0784557007759784,-0.6570896327307384,-0.4398329878954713,0.4406020294542778,6.375134995207417,1.3071283517404273,0.4406020294542778,-0.34822722873979567,0.6358549527434101,0.7184965916047329,0.38416999124999995,0.49674287398114536,-0.0784557007759784,0.38416999124999995,0.09744671117039397,2.57387865209091,-0.4398329878954713,-0.5633616250295993,-0.1377740898892939,-0.3786655961593971,0.039147774693997224,-0.257480688132458,0.24178007074161137,-0.19744656278221268,-0.3178843166402954,-1.274679154319205,0.0683384434312082,0.039147774693997224,-0.40920048646832796,-0.1377740898892939,0.12647339246637346,-0.7835665762622805,-0.28763581239975017,-0.22741793501362412,-0.16756559926044762,-0.257480688132458,1.043212757088441,1.25480593816419,1.1758959766163357,1.2285598984577069,-0.019484094638846886,0.29896409097336984,3.425644227114312,-1.0092905014838178,-0.3786655961593971,-0.28763581239975017,-0.34822722873979567,-0.10807109727927224,0.24178007074161137,0.09744671117039397,-0.5944992697412328,-0.6885448770013346,0.29896409097336984,-1.0420166552866306,-0.34822722873979567,0.12647339246637346,-0.34822722873979567,-0.10807109727927224,0.00987387634422139,0.0683384434312082,-0.04892699603974394,0.21307185932672598,0.5525977560753771,0.6358549527434101,-0.6570896327307384,1.25480593816419,-0.3786655961593971,-0.257480688132458,0.9897203299451159,0.8819955449514524,-0.4398329878954713,-0.22741793501362412,-0.28763581239975017,1.6164853429596542,0.12647339246637346,0.039147774693997224,-0.5323273632124869,0.29896409097336984,-0.10807109727927224,0.29896409097336984,-0.40920048646832796,-3.628539984810455,-0.5013952837666465,-0.7201085576537448,0.039147774693997224,-0.16756559926044762,-0.34822722873979567,8.08208815617794,-0.4398329878954713,0.2704105689905207,0.3558430944471442,-0.751782004665589,1.5909959114922732,0.00987387634422139,0.2704105689905207,-0.22741793501362412,-0.6570896327307384,0.0683384434312082,-0.6885448770013346,0.0683384434312082,0.1842851856536623,0.21307185932672598
2,451
Hyperreflexia
31
185
2.184163
0.02895
Q9NR77,Q15067,O15382,P37198,Q13409,Q92620,Q8N183,P82663,P35637,P35270,Q16625,Q9HCC0,Q9UDR5,Q5JRX3,O95831,P34897,Q6DKK2,Q9H0B6,O43464,Q8N2K0,Q6PI48,Q9NZ08,Q14739,P23378,O00400,Q86XL3,O43681,O75340,Q9P032,P35250,P20674
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
0,132,5,135,139,274,141,15,145,144,154,157,158,41,39,167,178,197,74,81,213,86,224,97,112,115,116,233,120,245,122
112,989,1204,2125,1889,440,725,5,584,2309,524,74,116,1329,1511,639,442,1133,1740,323,2380,588,276,494,402,233,1891,1394,2440,1989,1800,385,495,1271,423,900,642,2204,39,1640,1894,1332,1333,2435,1401,591,998,1581,678,2292,388,1458,1705,946,1003,445,1855,122,1335,861,97,2231,1643,1525,863,1093,1410,167,245,144,1529,145,1645,135,2157,737,2425,1469,2312,1045,1599,1650,1753,1287,1813,686,954,310,2072,1343,873,688,1759,1049,874,1293,15,472,2337,1765,783,372,139,331,1550,1421,224,273,2167,702,2188,132,749,1360,154,615,704,1613,1771,1428,41,431,1061,1616,178,2251,1431,1916,213,361,1827,1917,115,1557,1671,141,81,1968,1310,884,922,274,1019,621,1313,435,711,348,1876,712,518,2373,1441,2037,2446,1122,2009,1023,2088,1024,197,1444,157,1025,930,0,1934,1260,668,86,1072,120,669,158,2146,2124,983,2228,1031,1199,1200,490,810,1389,768
1.359227380748379,0.039147774693997224,-0.0784557007759784,-0.6570896327307384,-0.4398329878954713,0.4406020294542778,0.21307185932672598,6.375134995207417,0.29896409097336984,-1.0092905014838178,0.3558430944471442,1.6673111019721019,1.3071283517404273,-0.1377740898892939,-0.22741793501362412,0.2704105689905207,0.4406020294542778,-0.04892699603974394,-0.34822722873979567,0.6358549527434101,-1.4104788749430137,0.29896409097336984,0.7184965916047329,0.38416999124999995,0.49674287398114536,0.8277550450555999,-0.4398329878954713,-0.16756559926044762,-3.186817599807399,-0.5013952837666465,-0.3786655961593971,0.524705739682176,0.38416999124999995,-0.10807109727927224,0.46870852015967773,0.09744671117039397,0.2704105689905207,-0.751782004665589,2.57387865209091,-0.28763581239975017,-0.4398329878954713,-0.1377740898892939,-0.1377740898892939,-2.912061527756883,-0.16756559926044762,0.29896409097336984,0.039147774693997224,-0.257480688132458,0.24178007074161137,-0.9442059292838775,0.524705739682176,-0.19744656278221268,-0.3178843166402954,0.0683384434312082,0.039147774693997224,0.4406020294542778,-0.40920048646832796,1.2809952793799848,-0.1377740898892939,0.12647339246637346,1.4627685117962506,-0.7835665762622805,-0.28763581239975017,-0.22741793501362412,0.12647339246637346,-0.019484094638846886,-0.16756559926044762,1.043212757088441,0.8005384298975836,1.1758959766163357,-0.22741793501362412,1.1758959766163357,-0.28763581239975017,1.2285598984577069,-0.6885448770013346,0.21307185932672598,-2.303431129297027,-0.19744656278221268,-1.0092905014838178,0.00987387634422139,-0.257480688132458,-0.28763581239975017,-0.34822722873979567,-0.10807109727927224,-0.3786655961593971,0.24178007074161137,0.0683384434312082,0.6634697684133223,-0.5944992697412328,-0.1377740898892939,0.12647339246637346,0.24178007074161137,-0.34822722873979567,0.00987387634422139,0.12647339246637346,-0.10807109727927224,4.317676785197601,0.412422742929421,-1.10784497717408,-0.34822722873979567,0.1842851856536623,0.5525977560753771,1.2022567249634681,0.6358549527434101,-0.22741793501362412,-0.16756559926044762,0.8549072385416738,0.7459097574001678,-0.6885448770013346,0.24178007074161137,-0.7201085576537448,1.25480593816419,0.21307185932672598,-0.1377740898892939,1.1494772064741625,0.29896409097336984,0.24178007074161137,-0.257480688132458,-0.34822722873979567,-0.16756559926044762,2.57387865209091,0.46870852015967773,0.00987387634422139,-0.257480688132458,0.9897203299451159,-0.815463659775052,-0.16756559926044762,-0.4398329878954713,0.8819955449514524,0.5804195522374354,-0.3786655961593971,-0.4398329878954713,1.3332055793229365,-0.22741793501362412,-0.28763581239975017,1.2022567249634681,1.6164853429596542,-0.4705642099006684,-0.10807109727927224,0.12647339246637346,0.09744671117039397,0.7459097574001678,0.039147774693997224,0.29896409097336984,-0.10807109727927224,0.46870852015967773,0.24178007074161137,0.6081717477181001,-0.40920048646832796,0.24178007074161137,0.38416999124999995,-1.3084367659564569,-0.16756559926044762,-0.5323273632124869,-3.628539984810455,-0.019484094638846886,-0.5013952837666465,0.039147774693997224,-0.5944992697412328,0.039147774693997224,0.9359825972271626,-0.16756559926044762,1.1229999616061817,0.039147774693997224,0.09744671117039397,8.08208815617794,-0.4398329878954713,-0.0784557007759784,0.2704105689905207,1.5909959114922732,0.00987387634422139,1.3071283517404273,0.2704105689905207,1.1229999616061817,-0.6570896327307384,-0.6257415222865993,0.0683384434312082,-0.751782004665589,0.039147774693997224,-0.04892699603974394,-0.04892699603974394,0.412422742929421,0.1842851856536623,-0.1377740898892939,0.21307185932672598
2,451
Ion transmembrane transporter activity
28
77
2.162342
0.030592
Q93034,P20020,P13073,O75746,O95202,Q6NUK1,P41440,O15439,P24539,P12235,Q9H2D1,P06576,Q9UM00,P08195,P31930,O43808,Q8N4V1,Q9UJS0,P61421,Q02978,P53985,Q70HW3,O43772,O00400,O75947,O43681,P05026,P20674
Functions
GO Molecular function
msigdb_gomf
399,389,388,385,265,285,23,151,408,405,42,170,305,175,426,191,67,198,447,448,90,226,232,112,234,116,366,122
1983,112,1848,151,116,232,191,385,234,940,265,1215,1745,366,1578,170,1947,1518,175,944,1948,405,1221,388,1897,389,122,1405,905,466,1225,408,948,426,736,1230,737,23,2051,1232,2407,90,688,1344,1102,447,1814,1816,742,448,1768,1962,703,285,1305,840,226,67,1176,399,2253,2274,1836,1882,42,2040,1183,2289,761,2224,1381,1505,198,305,1029,809,768
-0.5013952837666465,1.359227380748379,-0.40920048646832796,1.1494772064741625,1.3071283517404273,0.8277550450555999,0.9359825972271626,0.524705739682176,0.8277550450555999,0.0683384434312082,0.7459097574001678,-0.0784557007759784,-0.34822722873979567,0.5525977560753771,-0.257480688132458,1.016496960173559,-0.4705642099006684,-0.22741793501362412,0.9897203299451159,0.0683384434312082,-0.4705642099006684,0.49674287398114536,-0.0784557007759784,0.524705739682176,-0.4398329878954713,0.524705739682176,1.2809952793799848,-0.16756559926044762,0.09744671117039397,0.412422742929421,-0.0784557007759784,0.49674287398114536,0.0683384434312082,0.46870852015967773,0.21307185932672598,-0.0784557007759784,0.21307185932672598,3.425644227114312,-0.5633616250295993,-0.0784557007759784,-1.7587385123710009,1.514217019711359,0.24178007074161137,-0.1377740898892939,-0.019484094638846886,0.4406020294542778,-0.3786655961593971,-0.3786655961593971,0.21307185932672598,0.4406020294542778,-0.34822722873979567,-0.4705642099006684,0.24178007074161137,0.7184965916047329,-0.10807109727927224,0.15541928815000872,0.8549072385416738,1.8185889485528128,-0.04892699603974394,0.524705739682176,-0.815463659775052,-0.8796010627908111,-0.3786655961593971,-0.40920048646832796,2.5501516672317077,-0.5323273632124869,-0.04892699603974394,-0.9118443106940877,0.21307185932672598,-0.751782004665589,-0.1377740898892939,-0.19744656278221268,0.9359825972271626,0.6910167868939782,0.039147774693997224,0.1842851856536623,0.21307185932672598
2,451
Alpha amino acid metabolic process
21
64
2.094021
0.036258
P17812,O15382,O60725,O75746,P31937,P35914,P16930,Q9HCC0,Q9UDR5,Q9BV57,P34897,P25325,P34896,Q9UJS0,Q92947,P00374,P30520,P23378,A1L0T0,Q9NRN7,O43708
Processes and pathways
GO Biological process
msigdb_gobp
253,5,9,385,391,267,26,157,158,30,167,296,297,198,336,200,345,97,104,109,244
104,2180,1207,5,1034,244,1849,9,2129,385,527,1515,200,1454,729,1401,1403,26,425,253,1587,97,1225,596,296,1004,2101,345,391,1336,297,167,267,1594,871,1234,2072,829,873,1958,1237,1013,651,2184,415,698,1431,511,1618,336,1313,2373,1441,2174,1370,1373,30,157,520,109,158,198,2340,1389
1.4369643345051797,-0.7201085576537448,-0.0784557007759784,6.375134995207417,0.00987387634422139,0.8005384298975836,-0.40920048646832796,5.95432640274315,-0.6570896327307384,0.524705739682176,0.3558430944471442,-0.22741793501362412,0.9090204913108676,-0.19744656278221268,0.21307185932672598,-0.16756559926044762,-0.16756559926044762,3.20020104613835,0.46870852015967773,0.7732568507472157,-0.257480688132458,1.4627685117962506,-0.0784557007759784,0.29896409097336984,0.6910167868939782,0.039147774693997224,-0.6257415222865993,0.6081717477181001,0.524705739682176,-0.1377740898892939,0.6910167868939782,1.043212757088441,0.7459097574001678,-0.257480688132458,0.12647339246637346,-0.0784557007759784,-0.5944992697412328,0.15541928815000872,0.12647339246637346,-0.4705642099006684,-0.0784557007759784,0.039147774693997224,0.2704105689905207,-0.7201085576537448,0.49674287398114536,0.24178007074161137,-0.16756559926044762,0.38416999124999995,-0.257480688132458,0.6358549527434101,-0.10807109727927224,-1.3084367659564569,-0.16756559926044762,-0.6885448770013346,-0.1377740898892939,-0.1377740898892939,3.109076697157546,1.1229999616061817,0.38416999124999995,1.4369643345051797,1.1229999616061817,0.9359825972271626,-1.10784497717408,-0.1377740898892939
2,451
Peripheral neuropathy
38
133
2.092947
0.036354
Q9NR77,Q15067,P35251,P04792,Q15041,Q8N183,P41440,O15460,P16930,Q9NSE4,P12235,P09651,O75306,P34897,O95831,P31930,P22626,Q96BR5,Q9NPL8,Q16836,Q9H0B6,O14802,O60313,P19404,Q92947,Q15120,O00330,Q8N2K0,Q6PI48,O95721,P42704,P22307,Q7Z392,O43681,Q13217,O94905,Q10713,Q03001
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
0,132,130,252,273,141,23,152,26,32,405,404,402,167,39,426,176,319,188,450,197,440,442,445,336,78,207,81,213,93,468,467,361,116,373,495,372,506
207,989,1204,440,1077,152,116,1511,1635,1132,442,2067,2380,494,402,1394,1212,1639,495,900,1854,642,1331,93,39,1215,1894,252,1745,2045,1333,591,404,1582,405,26,1585,1003,731,1521,445,1855,1405,467,1749,176,906,1461,2231,1643,1525,863,1410,426,167,130,866,2207,599,1469,23,468,1650,1286,1813,954,911,1152,830,2408,873,1759,1290,1049,1534,1235,1765,1543,506,1474,2304,372,2374,373,2166,1357,273,2167,2139,132,78,1482,615,450,1613,2418,1428,2297,213,361,2252,1829,1556,1557,141,81,1672,976,1019,336,319,711,1876,1927,1178,2403,2009,197,1838,2289,1025,188,0,1934,32,718,1072,1189,1128,1195,635,987,810
0.8819955449514524,0.039147774693997224,-0.0784557007759784,0.4406020294542778,-0.019484094638846886,1.1494772064741625,1.3071283517404273,-0.22741793501362412,-0.28763581239975017,-0.04892699603974394,0.4406020294542778,-0.5944992697412328,-1.4104788749430137,0.38416999124999995,0.49674287398114536,-0.16756559926044762,-0.0784557007759784,-0.28763581239975017,0.38416999124999995,0.09744671117039397,-0.40920048646832796,0.2704105689905207,-0.1377740898892939,1.4885192775711327,2.57387865209091,-0.0784557007759784,-0.4398329878954713,0.7732568507472157,-0.34822722873979567,-0.5633616250295993,-0.1377740898892939,0.29896409097336984,0.49674287398114536,-0.257480688132458,0.49674287398114536,3.20020104613835,-0.257480688132458,0.039147774693997224,0.21307185932672598,-0.22741793501362412,0.4406020294542778,-0.40920048646832796,-0.16756559926044762,0.412422742929421,-0.34822722873979567,0.9897203299451159,0.09744671117039397,-0.19744656278221268,-0.7835665762622805,-0.28763581239975017,-0.22741793501362412,0.12647339246637346,-0.16756559926044762,0.46870852015967773,1.043212757088441,1.25480593816419,0.12647339246637346,-0.751782004665589,0.29896409097336984,-0.19744656278221268,3.425644227114312,0.412422742929421,-0.28763581239975017,-0.10807109727927224,-0.3786655961593971,0.0683384434312082,0.09744671117039397,-0.04892699603974394,0.15541928815000872,-1.7587385123710009,0.12647339246637346,-0.34822722873979567,-0.10807109727927224,0.00987387634422139,-0.22741793501362412,-0.0784557007759784,-0.34822722873979567,-0.22741793501362412,0.38416999124999995,-0.19744656278221268,-0.9766874655426719,0.5525977560753771,-1.342323082785766,0.5525977560753771,-0.6885448770013346,-0.1377740898892939,0.7459097574001678,-0.6885448770013346,-0.6570896327307384,1.25480593816419,1.6419236197042295,-0.19744656278221268,0.29896409097336984,0.4406020294542778,-0.257480688132458,-1.9734899914383972,-0.16756559926044762,-0.9442059292838775,0.8819955449514524,0.5804195522374354,-0.815463659775052,-0.3786655961593971,-0.22741793501362412,-0.22741793501362412,1.2022567249634681,1.6164853429596542,-0.28763581239975017,0.0683384434312082,0.039147774693997224,0.6358549527434101,0.6634697684133223,0.24178007074161137,-0.40920048646832796,-0.4398329878954713,-0.04892699603974394,-1.652972814945418,-0.5013952837666465,0.9359825972271626,-0.3786655961593971,-0.9118443106940877,0.039147774693997224,0.9628823750360523,8.08208815617794,-0.4398329878954713,2.832301970314483,0.24178007074161137,0.00987387634422139,-0.04892699603974394,-0.019484094638846886,-0.04892699603974394,0.29896409097336984,0.0683384434312082,0.1842851856536623
2,451
Tetrapyrrole binding
7
14
2.082204
0.037324
O43169,Q16850,Q8WUJ1,P30519,Q9NRV9,O15173,Q8WYQ5
Functions
GO Molecular function
msigdb_gomf
128,36,11,202,80,56,317
672,56,128,944,592,202,778,36,11,317,543,2174,339,80
0.24178007074161137,1.9681243483352855,1.25480593816419,0.0683384434312082,0.29896409097336984,0.9090204913108676,0.1842851856536623,2.6683913673159614,5.2852521154266645,0.6634697684133223,0.3558430944471442,-0.6885448770013346,0.6358549527434101,1.6419236197042295
2,451
Abnormal circulating protein concentration
33
121
2.079754
0.037548
Q00059,P83436,P31483,O14979,P41440,P16930,Q9UDR5,Q9NWM8,Q5JRX3,O95831,P22626,Q9H0R6,Q96BR5,Q14126,Q9UJS0,Q8N1F7,Q13501,Q15120,O00330,P14174,P23786,Q8NFF5,P53985,Q9H845,Q96AX1,Q86U42,P35250,O75648,P49748,O43772,O00400,O75340,Q14C86
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
257,256,266,142,23,26,158,31,41,39,176,187,319,332,198,77,331,78,207,326,83,227,90,229,363,362,245,218,236,232,112,233,125
1448,2362,207,112,142,2182,1453,1329,232,1132,2380,233,218,641,1331,39,1396,942,1703,2098,2045,404,2434,2414,405,326,2050,26,1586,1749,176,1461,83,1410,266,1809,1337,245,1006,1230,866,2104,737,599,23,868,1149,1045,2352,236,773,911,1288,1651,90,1759,1290,874,1714,1346,1293,256,257,2184,694,783,2304,963,331,1057,332,2213,700,125,702,78,1241,450,1613,2418,41,881,1061,2419,1772,453,1173,361,2252,433,1917,362,77,227,1487,2058,1311,1252,1019,363,319,1927,2403,662,980,187,229,1690,1378,31,1189,158,2124,198,1075,1030,1939,809,490,636,2391
-0.19744656278221268,-1.274679154319205,0.8819955449514524,1.359227380748379,1.1758959766163357,-0.7201085576537448,-0.19744656278221268,-0.1377740898892939,0.8277550450555999,-0.04892699603974394,-1.4104788749430137,0.8277550450555999,0.8549072385416738,0.2704105689905207,-0.1377740898892939,2.57387865209091,-0.16756559926044762,0.0683384434312082,-0.3178843166402954,-0.6257415222865993,-0.5633616250295993,0.49674287398114536,-2.8344894951683424,-1.8655830315992803,0.49674287398114536,0.6358549527434101,-0.5633616250295993,3.20020104613835,-0.257480688132458,-0.34822722873979567,0.9897203299451159,-0.19744656278221268,1.5909959114922732,-0.16756559926044762,0.7459097574001678,-0.3786655961593971,-0.1377740898892939,0.8005384298975836,0.039147774693997224,-0.0784557007759784,0.12647339246637346,-0.6257415222865993,0.21307185932672598,0.29896409097336984,3.425644227114312,0.12647339246637346,-0.04892699603974394,0.00987387634422139,-1.2075530729273112,0.8277550450555999,0.1842851856536623,0.09744671117039397,-0.10807109727927224,-0.28763581239975017,1.514217019711359,-0.34822722873979567,-0.10807109727927224,0.12647339246637346,-0.3178843166402954,-0.1377740898892939,-0.10807109727927224,0.7732568507472157,0.7732568507472157,-0.7201085576537448,0.24178007074161137,0.1842851856536623,-0.9766874655426719,0.0683384434312082,0.6358549527434101,0.00987387634422139,0.6358549527434101,-0.751782004665589,0.24178007074161137,1.2809952793799848,0.24178007074161137,1.6419236197042295,-0.0784557007759784,0.4406020294542778,-0.257480688132458,-1.9734899914383972,2.57387865209091,0.12647339246637346,0.00987387634422139,-2.1189915114141065,-0.34822722873979567,0.4406020294542778,-0.04892699603974394,0.5804195522374354,-0.815463659775052,0.46870852015967773,-0.4398329878954713,0.5804195522374354,1.6673111019721019,0.8549072385416738,-0.19744656278221268,-0.5633616250295993,-0.10807109727927224,-0.0784557007759784,0.039147774693997224,0.5804195522374354,0.6634697684133223,-0.4398329878954713,-1.652972814945418,0.2704105689905207,0.0683384434312082,0.9628823750360523,0.8549072385416738,-0.28763581239975017,-0.1377740898892939,2.9019854718131817,-0.04892699603974394,1.1229999616061817,-0.6257415222865993,0.9359825972271626,0.00987387634422139,0.039147774693997224,-0.4398329878954713,0.1842851856536623,0.412422742929421,0.29896409097336984,-1.4791407275236588
2,451
Muscle weakness
59
222
2.077126
0.03779
Q9NR77,Q15067,P35251,P04792,P37198,P13073,Q8N183,P82663,P31483,P35637,Q6NUK1,P35270,O14979,P41440,O15460,Q13126,Q9Y6M9,Q9Y375,Q9NWM8,P17612,P12235,Q15165,P09651,O75306,P34897,O95831,Q96GM8,Q9Y2Z4,Q6DKK2,P22626,O43676,Q96BR5,Q9NPL8,P61981,Q4J6C6,P00374,Q15120,Q13501,P23786,Q6PI48,P61978,Q8NFF5,O95721,Q9H845,Q70HW3,Q14739,Q8IUX1,Q86U42,Q7Z392,O75648,P48651,Q92804,P49748,O43772,O00400,O75340,O43681,Q9P032,Q10713
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
0,132,130,252,135,388,141,15,266,145,285,144,142,23,152,415,421,159,31,407,405,35,404,402,167,39,435,173,178,176,174,319,188,311,71,200,78,331,83,213,330,227,93,229,226,224,101,362,361,218,222,110,236,232,112,233,116,120,372
2362,112,2125,1205,440,142,1077,152,2182,174,116,232,1132,442,1740,494,402,233,1891,443,1394,218,495,900,901,642,93,39,200,1215,1081,1894,942,1703,729,677,252,1745,1082,1217,2098,2441,2045,1333,2435,1400,819,404,2434,1582,678,2414,1084,405,388,679,562,407,946,731,1521,445,1335,861,1749,176,1461,83,1525,1410,1593,266,167,130,144,1006,145,866,2104,135,685,737,2207,1095,599,1469,23,468,2312,2019,1045,2352,222,1286,2347,236,1413,1813,773,911,1754,2071,1152,2072,2162,2324,775,777,1343,1758,873,1759,1290,1049,1534,2133,1235,330,311,15,1763,1543,1012,2184,1474,372,1108,415,745,331,2313,1057,1421,2166,2213,700,2138,224,2113,2139,132,78,1241,35,749,1482,792,879,1613,2418,1771,71,1428,1016,881,616,431,1061,178,2251,285,656,213,2305,226,361,2252,362,657,101,1557,1671,141,1728,707,227,976,884,2399,1311,1019,110,2033,542,319,435,1927,544,2037,1370,2446,1122,2403,662,546,2219,2194,229,2289,188,930,0,1934,31,1185,2222,1072,120,1189,2146,1128,1976,2228,2179,1075,173,159,1200,671,810,2391,421
-1.274679154319205,1.359227380748379,-0.6570896327307384,-0.0784557007759784,0.4406020294542778,1.1758959766163357,-0.019484094638846886,1.1494772064741625,-0.7201085576537448,0.9897203299451159,1.3071283517404273,0.8277550450555999,-0.04892699603974394,0.4406020294542778,-0.34822722873979567,0.38416999124999995,0.49674287398114536,0.8277550450555999,-0.4398329878954713,0.4406020294542778,-0.16756559926044762,0.8549072385416738,0.38416999124999995,0.09744671117039397,0.09744671117039397,0.2704105689905207,1.4885192775711327,2.57387865209091,0.9090204913108676,-0.0784557007759784,-0.019484094638846886,-0.4398329878954713,0.0683384434312082,-0.3178843166402954,0.21307185932672598,0.24178007074161137,0.7732568507472157,-0.34822722873979567,-0.019484094638846886,-0.0784557007759784,-0.6257415222865993,-3.346054874636426,-0.5633616250295993,-0.1377740898892939,-2.912061527756883,-0.16756559926044762,0.15541928815000872,0.49674287398114536,-2.8344894951683424,-0.257480688132458,0.24178007074161137,-1.8655830315992803,-0.019484094638846886,0.49674287398114536,0.524705739682176,0.24178007074161137,0.3274413616771643,0.49674287398114536,0.0683384434312082,0.21307185932672598,-0.22741793501362412,0.4406020294542778,-0.1377740898892939,0.12647339246637346,-0.34822722873979567,0.9897203299451159,-0.19744656278221268,1.5909959114922732,-0.22741793501362412,-0.16756559926044762,-0.257480688132458,0.7459097574001678,1.043212757088441,1.25480593816419,1.1758959766163357,0.039147774693997224,1.1758959766163357,0.12647339246637346,-0.6257415222865993,1.2285598984577069,0.24178007074161137,0.21307185932672598,-0.751782004665589,-0.019484094638846886,0.29896409097336984,-0.19744656278221268,3.425644227114312,0.412422742929421,-1.0092905014838178,-0.5323273632124869,0.00987387634422139,-1.2075530729273112,0.8549072385416738,-0.10807109727927224,-1.174186146206551,0.8277550450555999,-0.16756559926044762,-0.3786655961593971,0.1842851856536623,0.09744671117039397,-0.34822722873979567,-0.5944992697412328,-0.04892699603974394,-0.5944992697412328,-0.6885448770013346,-1.0420166552866306,0.1842851856536623,0.1842851856536623,-0.1377740898892939,-0.34822722873979567,0.12647339246637346,-0.34822722873979567,-0.10807109727927224,0.00987387634422139,-0.22741793501362412,-0.6570896327307384,-0.0784557007759784,0.6358549527434101,0.6634697684133223,4.317676785197601,-0.34822722873979567,-0.22741793501362412,0.039147774693997224,-0.7201085576537448,-0.19744656278221268,0.5525977560753771,-0.019484094638846886,0.49674287398114536,0.21307185932672598,0.6358549527434101,-1.0092905014838178,0.00987387634422139,-0.16756559926044762,-0.6885448770013346,-0.751782004665589,0.24178007074161137,-0.6570896327307384,0.8549072385416738,-0.6257415222865993,-0.6570896327307384,1.25480593816419,1.6419236197042295,-0.0784557007759784,2.6919218922452197,0.21307185932672598,-0.19744656278221268,0.1842851856536623,0.12647339246637346,-0.257480688132458,-1.9734899914383972,-0.34822722873979567,1.7431723198248983,-0.16756559926044762,0.039147774693997224,0.12647339246637346,0.29896409097336984,0.46870852015967773,0.00987387634422139,0.9897203299451159,-0.815463659775052,0.7184965916047329,0.2704105689905207,0.8819955449514524,-0.9766874655426719,0.8549072385416738,0.5804195522374354,-0.815463659775052,0.5804195522374354,0.2704105689905207,1.4627685117962506,-0.22741793501362412,-0.28763581239975017,1.2022567249634681,-0.3178843166402954,0.24178007074161137,0.8549072385416738,0.0683384434312082,0.12647339246637346,-1.5830700950355348,-0.10807109727927224,0.039147774693997224,1.4111063529203423,-0.5323273632124869,0.3558430944471442,0.6634697684133223,0.46870852015967773,-0.4398329878954713,0.3558430944471442,-0.5323273632124869,-0.1377740898892939,-3.628539984810455,-0.019484094638846886,-1.652972814945418,0.2704105689905207,0.3558430944471442,-0.751782004665589,-0.7201085576537448,0.8549072385416738,-0.9118443106940877,0.9628823750360523,0.09744671117039397,8.08208815617794,-0.4398329878954713,2.9019854718131817,-0.04892699603974394,-0.751782004665589,0.00987387634422139,1.3071283517404273,-0.04892699603974394,-0.6570896327307384,-0.019484094638846886,-0.4705642099006684,-0.751782004665589,-0.6885448770013346,0.00987387634422139,1.016496960173559,1.1229999616061817,-0.04892699603974394,0.2704105689905207,0.1842851856536623,-1.4791407275236588,0.49674287398114536
2,451
Hyporeflexia
23
94
2.068784
0.038566
Q9NR77,Q15067,P35251,P04792,P83436,P35914,P35637,O14979,P41440,Q9NSE4,O95831,Q96BR5,O95453,P61981,Q9H0B6,Q13501,Q15120,Q8N2K0,Q6PI48,Q96AX1,O75648,P23378,O43681
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
0,132,130,252,256,267,145,142,23,32,39,319,307,311,197,331,78,81,213,363,218,97,116
142,1077,2182,116,1511,1850,218,900,1854,901,2204,307,39,942,1332,252,1745,2098,2045,499,405,1003,1521,1855,1405,97,906,596,2231,1643,130,145,267,737,1095,599,1469,23,1286,954,911,1152,829,830,2408,1759,1290,2133,1235,311,256,1763,1012,1474,372,2374,745,331,1057,2166,2213,2139,132,78,879,615,1613,2418,213,361,2252,1557,81,1175,1728,976,2004,363,319,1927,2446,1178,197,2289,0,32,668,1072,1189,669,1128,1075,582,671
1.1758959766163357,-0.019484094638846886,-0.7201085576537448,1.3071283517404273,-0.22741793501362412,-0.40920048646832796,0.8549072385416738,0.09744671117039397,-0.40920048646832796,0.09744671117039397,-0.751782004665589,0.6634697684133223,2.57387865209091,0.0683384434312082,-0.1377740898892939,0.7732568507472157,-0.34822722873979567,-0.6257415222865993,-0.5633616250295993,0.38416999124999995,0.49674287398114536,0.039147774693997224,-0.22741793501362412,-0.40920048646832796,-0.16756559926044762,1.4627685117962506,0.09744671117039397,0.29896409097336984,-0.7835665762622805,-0.28763581239975017,1.25480593816419,1.1758959766163357,0.7459097574001678,0.21307185932672598,-0.019484094638846886,0.29896409097336984,-0.19744656278221268,3.425644227114312,-0.10807109727927224,0.0683384434312082,0.09744671117039397,-0.04892699603974394,0.15541928815000872,0.15541928815000872,-1.7587385123710009,-0.34822722873979567,-0.10807109727927224,-0.6570896327307384,-0.0784557007759784,0.6634697684133223,0.7732568507472157,-0.34822722873979567,0.039147774693997224,-0.19744656278221268,0.5525977560753771,-1.342323082785766,0.21307185932672598,0.6358549527434101,0.00987387634422139,-0.6885448770013346,-0.751782004665589,-0.6570896327307384,1.25480593816419,1.6419236197042295,0.12647339246637346,0.29896409097336984,-0.257480688132458,-1.9734899914383972,0.8819955449514524,0.5804195522374354,-0.815463659775052,-0.22741793501362412,1.6164853429596542,-0.04892699603974394,-0.3178843166402954,0.0683384434312082,-0.5013952837666465,0.5804195522374354,0.6634697684133223,-0.4398329878954713,-3.628539984810455,-0.04892699603974394,0.9359825972271626,-0.9118443106940877,8.08208815617794,2.832301970314483,0.2704105689905207,0.00987387634422139,-0.04892699603974394,0.2704105689905207,-0.019484094638846886,0.00987387634422139,0.3274413616771643,0.2704105689905207
2,451
Nucleotide transport
6
12
2.065772
0.03885
Q9H2D1,Q9BSK2,O00400,P41440,O15439,O43808
Processes and pathways
GO Biological process
msigdb_gobp
42,82,112,23,151,191
112,151,191,1578,405,1221,23,285,1176,82,42,2289
1.359227380748379,1.1494772064741625,0.9359825972271626,-0.257480688132458,0.49674287398114536,-0.0784557007759784,3.425644227114312,0.7184965916047329,-0.04892699603974394,1.6164853429596542,2.5501516672317077,-0.9118443106940877
2,451
Organophosphate ester transmembrane transporter activity
6
12
2.065772
0.03885
Q9H2D1,Q9BSK2,O00400,P41440,O15439,O43808
Functions
GO Molecular function
msigdb_gomf
42,82,112,23,151,191
112,151,191,1578,405,1221,23,285,1176,82,42,2289
1.359227380748379,1.1494772064741625,0.9359825972271626,-0.257480688132458,0.49674287398114536,-0.0784557007759784,3.425644227114312,0.7184965916047329,-0.04892699603974394,1.6164853429596542,2.5501516672317077,-0.9118443106940877
2,451
Nucleotide transmembrane transporter activity
6
12
2.065772
0.03885
Q9H2D1,Q9BSK2,O00400,P41440,O15439,O43808
Functions
GO Molecular function
msigdb_gomf
42,82,112,23,151,191
112,151,191,1578,405,1221,23,285,1176,82,42,2289
1.359227380748379,1.1494772064741625,0.9359825972271626,-0.257480688132458,0.49674287398114536,-0.0784557007759784,3.425644227114312,0.7184965916047329,-0.04892699603974394,1.6164853429596542,2.5501516672317077,-0.9118443106940877
2,451
S phase
12
81
2.020998
0.04328
Q16763,P40938,P35251,P31751,P28070,Q96DE5,O75832,Q9Y2S7,P28074,P41440,P35250,P28072
Processes and pathways
Reactome Pathways
msigdb_reactome
194,221,130,254,98,70,199,181,16,23,245,94
1131,1203,2197,1206,1078,1635,199,1274,1084,1585,532,1407,1462,1142,733,823,563,1465,1092,98,94,16,1409,1005,254,1145,1901,1808,1902,1094,245,130,1339,1952,1148,221,23,1007,870,1151,1470,602,410,1098,2282,566,1652,536,1653,1473,1955,961,962,1053,1054,1548,2136,1299,1479,1357,1303,1963,1913,194,1720,1724,1249,70,289,1680,927,2288,2195,581,933,1383,634,721,1195,181,768
-0.04892699603974394,-0.0784557007759784,-0.751782004665589,-0.0784557007759784,-0.019484094638846886,-0.28763581239975017,0.9090204913108676,-0.10807109727927224,-0.019484094638846886,-0.257480688132458,0.3558430944471442,-0.16756559926044762,-0.19744656278221268,-0.04892699603974394,0.21307185932672598,0.15541928815000872,0.3274413616771643,-0.19744656278221268,-0.019484094638846886,1.4627685117962506,1.4885192775711327,4.232767107176705,-0.16756559926044762,0.039147774693997224,0.7732568507472157,-0.04892699603974394,-0.4398329878954713,-0.3786655961593971,-0.4398329878954713,-0.019484094638846886,0.8005384298975836,1.25480593816419,-0.1377740898892939,-0.4705642099006684,-0.04892699603974394,0.8549072385416738,3.425644227114312,0.039147774693997224,0.12647339246637346,-0.04892699603974394,-0.19744656278221268,0.29896409097336984,0.49674287398114536,-0.019484094638846886,-0.9118443106940877,0.3274413616771643,-0.28763581239975017,0.3558430944471442,-0.28763581239975017,-0.19744656278221268,-0.4705642099006684,0.0683384434312082,0.0683384434312082,0.00987387634422139,0.00987387634422139,-0.22741793501362412,-0.6570896327307384,-0.10807109727927224,-0.19744656278221268,-0.1377740898892939,-0.10807109727927224,-0.4705642099006684,-0.4398329878954713,0.9359825972271626,-0.3178843166402954,-0.3178843166402954,-0.0784557007759784,1.768360141085143,0.7184965916047329,-0.28763581239975017,0.09744671117039397,-0.9118443106940877,-0.7201085576537448,0.3274413616771643,0.09744671117039397,-0.1377740898892939,0.29896409097336984,0.24178007074161137,-0.04892699603974394,0.9897203299451159,0.21307185932672598
2,451
Abnormal glucose homeostasis
46
150
2.015094
0.043895
Q14738,Q00059,P31751,P83436,Q92620,Q8N183,P35914,Q9Y2R9,Q9Y6M9,P16930,Q9HCC0,Q9Y375,P43304,Q9NSE4,P17612,P12235,O75306,O75844,P51570,O43676,Q9H0R6,Q9NPL8,O95453,P50213,Q16836,O14802,Q4J6C6,O60313,P19404,Q92947,O00330,P22695,P23786,Q9NP81,Q9Y4P3,P53985,Q9H845,P42704,Q8IUX1,P49748,O43772,Q13217,Q9P032,P35250,O00170,P49419
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
131,257,254,256,274,141,267,420,421,26,157,159,155,32,407,405,402,48,427,174,187,188,307,310,450,440,71,442,445,336,207,209,83,215,490,90,229,468,101,236,232,373,120,245,121,123
1448,121,207,989,440,584,524,174,1329,232,639,442,1850,494,402,1037,1394,1989,1800,1212,48,641,2015,1639,1271,900,307,1331,2402,1515,1215,942,677,2246,1516,997,1217,1334,1582,2414,2292,405,679,562,26,1279,407,1747,445,209,83,596,1525,1409,1951,254,1809,1337,245,1006,267,1645,2104,685,2157,2207,2425,599,1859,950,468,155,123,1287,236,1813,310,1903,427,777,90,1157,1758,1290,1049,1346,1815,1293,471,256,257,1052,1162,1474,373,1768,131,702,1360,792,450,1613,2236,71,2372,1061,1916,1173,1485,1917,657,101,1557,141,1672,2399,922,885,274,1019,336,847,1316,2373,1370,758,2219,1024,187,229,157,215,188,1378,32,1185,1629,2276,120,2124,983,420,1197,159,1385,1939,671,987,490,421
-0.19744656278221268,1.2809952793799848,0.8819955449514524,0.039147774693997224,0.4406020294542778,0.29896409097336984,0.3558430944471442,0.9897203299451159,-0.1377740898892939,0.8277550450555999,0.2704105689905207,0.4406020294542778,-0.40920048646832796,0.38416999124999995,0.49674287398114536,0.00987387634422139,-0.16756559926044762,-0.5013952837666465,-0.3786655961593971,-0.0784557007759784,2.310642065567253,0.2704105689905207,-0.5323273632124869,-0.28763581239975017,-0.10807109727927224,0.09744671117039397,0.6634697684133223,-0.1377740898892939,-1.652972814945418,-0.22741793501362412,-0.0784557007759784,0.0683384434312082,0.24178007074161137,-0.815463659775052,-0.22741793501362412,0.039147774693997224,-0.0784557007759784,-0.1377740898892939,-0.257480688132458,-1.8655830315992803,-0.9442059292838775,0.49674287398114536,0.24178007074161137,0.3274413616771643,3.20020104613835,-0.10807109727927224,0.49674287398114536,-0.34822722873979567,0.4406020294542778,0.8819955449514524,1.5909959114922732,0.29896409097336984,-0.22741793501362412,-0.16756559926044762,-0.4705642099006684,0.7732568507472157,-0.3786655961593971,-0.1377740898892939,0.8005384298975836,0.039147774693997224,0.7459097574001678,-0.28763581239975017,-0.6257415222865993,0.24178007074161137,-0.6885448770013346,-0.751782004665589,-2.303431129297027,0.29896409097336984,-0.40920048646832796,0.0683384434312082,0.412422742929421,1.1229999616061817,1.2809952793799848,-0.10807109727927224,0.8277550450555999,-0.3786655961593971,0.6634697684133223,-0.4398329878954713,0.46870852015967773,0.1842851856536623,1.514217019711359,-0.04892699603974394,-0.34822722873979567,-0.10807109727927224,0.00987387634422139,-0.1377740898892939,-0.3786655961593971,-0.10807109727927224,0.412422742929421,0.7732568507472157,0.7732568507472157,0.00987387634422139,-0.04892699603974394,-0.19744656278221268,0.5525977560753771,-0.34822722873979567,1.25480593816419,0.24178007074161137,-0.1377740898892939,0.1842851856536623,0.4406020294542778,-0.257480688132458,-0.7835665762622805,1.7431723198248983,-1.3084367659564569,0.00987387634422139,-0.4398329878954713,-0.04892699603974394,-0.19744656278221268,-0.4398329878954713,0.2704105689905207,1.4627685117962506,-0.22741793501362412,1.2022567249634681,-0.28763581239975017,-1.5830700950355348,0.09744671117039397,0.12647339246637346,0.7459097574001678,0.039147774693997224,0.6358549527434101,0.15541928815000872,-0.10807109727927224,-1.3084367659564569,-0.1377740898892939,0.21307185932672598,-0.751782004665589,0.039147774693997224,0.9628823750360523,0.8549072385416738,1.1229999616061817,0.8819955449514524,0.9628823750360523,-0.1377740898892939,2.832301970314483,-0.04892699603974394,-0.257480688132458,-0.8796010627908111,1.3071283517404273,-0.6257415222865993,0.0683384434312082,0.49674287398114536,-0.04892699603974394,1.1229999616061817,-0.1377740898892939,-0.4398329878954713,0.2704105689905207,0.0683384434312082,0.412422742929421,0.49674287398114536
2,451
Proteasome beta-type subunit, conserved site [IPR016050]
7
8
2.007541
0.044692
P25789,P20618,P28070,P28074,Q99436,P49721,P28072
Sequence
InterPro Conserved site
interpro_conserved_site
563,532,98,16,289,410,94
532,563,98,94,16,602,410,289
0.3558430944471442,0.3274413616771643,1.4627685117962506,1.4885192775711327,4.232767107176705,0.29896409097336984,0.49674287398114536,0.7184965916047329
2,451
Threonine type endopeptidase activity
7
8
2.007541
0.044692
P25789,P20618,P28070,P28074,Q99436,P49721,P28072
Functions
GO Molecular function
msigdb_gomf
563,532,98,16,289,410,94
532,563,98,94,16,602,410,289
0.3558430944471442,0.3274413616771643,1.4627685117962506,1.4885192775711327,4.232767107176705,0.29896409097336984,0.49674287398114536,0.7184965916047329
2,451
Reduced tendon reflexes
32
127
1.989794
0.046614
Q9NR77,Q14738,Q15067,P35251,P04792,P83436,Q15041,P35914,P35637,O14979,P41440,Q96AY3,Q9NSE4,O95831,Q96BR5,O95453,P61981,Q9H0B6,Q13501,Q15120,O60701,Q8N2K0,Q6PI48,P61978,O95721,Q96AX1,Q7Z392,O75648,P23378,O75340,O43681,Q13217
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
0,131,132,130,252,256,273,267,145,142,23,288,32,39,319,307,311,197,331,78,323,81,213,330,93,363,361,218,97,233,116,373
989,142,1077,2182,116,1511,1132,442,323,1850,233,1891,218,900,1854,901,2204,307,93,39,942,1332,252,1745,2098,2045,2434,499,2414,405,1003,731,1521,1855,1405,1749,97,906,596,2231,1643,130,145,267,737,1095,599,1469,23,1286,954,773,911,2071,1152,829,830,777,2408,873,1759,1290,1534,2133,1235,330,311,256,742,1763,1543,506,1012,2184,1474,372,2374,745,373,331,2313,1057,2166,2213,131,273,2139,132,78,1241,879,615,1613,2418,1428,213,361,2252,1557,81,1175,1728,976,1310,1311,1019,2004,363,288,319,1927,2446,1178,662,197,1444,2289,0,32,668,1072,1189,669,1128,1075,582,671
0.039147774693997224,1.1758959766163357,-0.019484094638846886,-0.7201085576537448,1.3071283517404273,-0.22741793501362412,-0.04892699603974394,0.4406020294542778,0.6358549527434101,-0.40920048646832796,0.8277550450555999,-0.4398329878954713,0.8549072385416738,0.09744671117039397,-0.40920048646832796,0.09744671117039397,-0.751782004665589,0.6634697684133223,1.4885192775711327,2.57387865209091,0.0683384434312082,-0.1377740898892939,0.7732568507472157,-0.34822722873979567,-0.6257415222865993,-0.5633616250295993,-2.8344894951683424,0.38416999124999995,-1.8655830315992803,0.49674287398114536,0.039147774693997224,0.21307185932672598,-0.22741793501362412,-0.40920048646832796,-0.16756559926044762,-0.34822722873979567,1.4627685117962506,0.09744671117039397,0.29896409097336984,-0.7835665762622805,-0.28763581239975017,1.25480593816419,1.1758959766163357,0.7459097574001678,0.21307185932672598,-0.019484094638846886,0.29896409097336984,-0.19744656278221268,3.425644227114312,-0.10807109727927224,0.0683384434312082,0.1842851856536623,0.09744671117039397,-0.5944992697412328,-0.04892699603974394,0.15541928815000872,0.15541928815000872,0.1842851856536623,-1.7587385123710009,0.12647339246637346,-0.34822722873979567,-0.10807109727927224,-0.22741793501362412,-0.6570896327307384,-0.0784557007759784,0.6358549527434101,0.6634697684133223,0.7732568507472157,0.21307185932672598,-0.34822722873979567,-0.22741793501362412,0.38416999124999995,0.039147774693997224,-0.7201085576537448,-0.19744656278221268,0.5525977560753771,-1.342323082785766,0.21307185932672598,0.5525977560753771,0.6358549527434101,-1.0092905014838178,0.00987387634422139,-0.6885448770013346,-0.751782004665589,1.25480593816419,0.7459097574001678,-0.6570896327307384,1.25480593816419,1.6419236197042295,-0.0784557007759784,0.12647339246637346,0.29896409097336984,-0.257480688132458,-1.9734899914383972,-0.16756559926044762,0.8819955449514524,0.5804195522374354,-0.815463659775052,-0.22741793501362412,1.6164853429596542,-0.04892699603974394,-0.3178843166402954,0.0683384434312082,-0.10807109727927224,-0.10807109727927224,0.039147774693997224,-0.5013952837666465,0.5804195522374354,0.7184965916047329,0.6634697684133223,-0.4398329878954713,-3.628539984810455,-0.04892699603974394,0.2704105689905207,0.9359825972271626,-0.16756559926044762,-0.9118443106940877,8.08208815617794,2.832301970314483,0.2704105689905207,0.00987387634422139,-0.04892699603974394,0.2704105689905207,-0.019484094638846886,0.00987387634422139,0.3274413616771643,0.2704105689905207
2,451
Organic acid transmembrane transporter activity
6
16
1.987362
0.046882
Q9H2D1,P08195,P08183,P41440,O15439,P53985
Functions
GO Molecular function
msigdb_gomf
42,175,18,23,151,90
1848,151,385,18,175,23,90,448,703,1305,42,2040,1183,2224,198,768
-0.40920048646832796,1.1494772064741625,0.524705739682176,4.147422713743819,0.9897203299451159,3.425644227114312,1.514217019711359,0.4406020294542778,0.24178007074161137,-0.10807109727927224,2.5501516672317077,-0.5323273632124869,-0.04892699603974394,-0.751782004665589,0.9359825972271626,0.21307185932672598
2,451
Predicted membrane proteins
102
396
4.12392
0.000037
Q6UXD5,P05067,P11117,Q8IXU6,Q567V2,Q9UIQ6,Q9C0H2,P42892,Q14108,Q15392,Q8IV08,P02786,Q06481,Q8NC54,O75976,P11279,P11717,Q15904,O94813,Q14739,Q15375,Q5J8M3,Q99720,O60830,Q99523,Q9Y624,Q5BJF2,Q9UBM7,Q9H2J7,Q8WTV0,O15118,Q14849,P51790,Q92542,P10321,O00461,O43657,Q9Y320,Q9Y6C9,O15269,Q14126,O14967,P35613,O15439,Q03519,Q99595,Q92692,Q8N4V1,Q9HD45,Q9H9B4,P24390,P08195,Q9Y3E5,Q8IY95,Q9Y487,O43464,Q6NT16,P55011,Q5W0Z9,Q9H3N1,Q96G23,Q9Y639,Q9BUN8,Q8WY22,Q15041,O15127,Q9UNK0,P48651,Q8TCJ2,Q9UBU6,P05026,O43808,O14880,Q8TB61,Q9BVK6,P28288,Q93050,Q9BQE5,Q9UH62,Q9NS69,Q8IXI2,Q658P3,Q5T4S7,Q15631,P56134,P49755,Q9UG56,Q96N66,Q3SXM5,Q9Y3P9,P60903,Q9UDW1,Q9H4I3,Q15758,P46783,P05556,P50402,Q96IX5,P01889,P00403,Q12907,Q8TCG1
Functions
Protein Atlas Protein class
protein_atlas_protein_class
1,3,4,6,7,8,13,15,18,19,21,22,26,29,28,30,32,36,40,42,44,45,48,47,49,50,52,53,54,55,58,59,60,61,63,67,73,83,86,88,89,91,96,95,98,103,102,115,118,123,131,134,146,153,158,147,152,149,151,161,166,169,167,176,173,178,180,182,197,200,190,188,187,204,206,202,210,211,212,226,230,229,239,238,248,247,273,271,266,283,278,304,303,297,290,285,292,316,307,306,329,331
2222,2078,1401,621,1738,67,2240,553,2396,663,1872,2348,361,187,899,91,58,2390,178,2366,554,88,340,555,95,1046,2402,1048,147,2054,73,1741,587,625,188,2271,1476,1640,47,1537,2255,520,754,1925,849,664,951,2055,665,953,1411,903,28,1478,40,363,955,904,321,1005,2242,1174,1412,1050,2056,717,1593,434,957,306,307,22,629,1645,1646,1299,190,3,630,285,909,2186,134,2168,1542,1056,63,4,1693,30,32,451,721,672,452,1183,910,389,1746,1699,1836,856,131,1597,2026,202,1839,1932,366,1784,860,765,96,1654,914,1485,638,1060,1116,15,770,290,437,1312,182,1993,2171,247,2409,1120,292,1607,2117,1313,1122,1556,60,411,863,1969,326,149,248,1431,412,919,1893,278,1251,370,603,1845,869,817,1071,2313,818,2435,98,2212,2196,26,2065,2430,328,1436,2383,329,1498,2143,690,2066,1660,2144,1259,2230,18,89,1025,569,1662,42,2304,59,1852,538,173,1663,44,2387,19,826,238,395,297,36,927,876,1265,877,1382,2148,266,1383,1758,828,7,52,45,2417,1566,1133,441,2213,239,1384,741,151,229,152,2328,1625,571,1029,1508,2036,351,1,442,1945,1805,880,742,2397,2322,1512,2068,354,929,21,2284,418,1948,230,6,543,153,503,2151,1276,115,780,1446,1721,2443,29,379,471,2152,204,331,197,647,1515,55,473,648,2154,176,61,883,884,698,102,2388,504,380,210,506,356,382,1083,507,1332,333,1334,835,166,700,316,1910,271,1336,2128,2129,1281,1088,49,2100,103,48,2406,987,837,211,1456,2046,1813,2101,167,1147,2452,1521,206,13,2048,1284,2102,839,1862,2159,54,1814,1772,161,1150,303,2338,658,2296,123,1815,787,788,118,2251,704,1579,445,548,1732,1580,2447,2163,226,843,2379,1464,994,1819,790,1465,706,2252,1466,891,1774,1581,619,53,516,200,2108,1583,304,2015,273,1288,212,1396,8,1290,180,661,707,1161,426,1041,1532,1293,2111,83,1398,146,283,1351,158,1162,2238,709,1635,793,50,169,895,86
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2,453
Innate immune system
25
229
3.644172
0.000268
P05067,O00584,Q99538,P06280,Q9BTY2,P17900,P61916,Q8IV08,P10253,P11279,P15586,P11717,P16278,P42785,Q99519,Q92820,P10619,P07686,Q92542,P10321,Q13510,P08236,O75874,O60784,Q14738
Processes and pathways
Reactome Pathways
msigdb_reactome
3,5,9,10,14,16,17,21,23,30,31,32,33,35,38,39,46,51,61,63,71,84,93,105,107
518,1637,1534,621,2347,663,5,711,1588,2390,1165,753,2254,449,362,1591,1826,105,799,628,93,955,1539,956,957,1006,307,1298,559,629,3,10,1110,909,1744,591,631,51,1009,1692,84,2057,1594,1542,1010,2021,1832,23,63,46,2022,593,30,32,1303,2367,1882,1111,1544,364,1883,1694,2025,1545,31,2341,33,286,111,16,1649,2243,911,245,390,2190,1651,760,455,1187,392,675,1701,1424,762,1886,1307,1189,1839,2061,764,1788,765,1934,1653,1935,1484,861,807,638,1427,35,1310,2226,728,1062,183,639,184,1554,862,1843,1608,368,457,1366,680,863,1017,1968,1557,600,1611,1612,729,459,491,293,1559,527,682,920,369,2283,2401,1894,261,528,17,1995,1370,1253,415,1070,294,463,295,565,1939,1021,814,345,1371,1895,1199,2065,1374,1203,1497,1798,1498,374,71,160,1848,2119,1974,1025,1322,2353,107,926,1851,1262,825,2437,239,2177,241,1210,742,1903,21,501,2004,471,696,61,355,39,210,885,333,887,270,2286,1727,475,1088,38,1574,9,655,1812,1089,14,225,2130,1034,2279,839,1772,2050,704,942,1466,1774,1865,2109,360,1468,945,1777,2221,1041,662,1985,158,2019
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2,453
Endoplasmic reticulum
105
376
3.477844
0.000505
Q6UXD5,P05067,O00584,O75503,Q9BTY2,P61916,Q14108,Q15392,Q8IV08,Q06481,Q15904,Q14739,Q5J8M3,P10619,Q99720,Q99523,Q5BJF2,Q9UBM7,O15118,Q14849,Q92542,P10321,Q13510,Q13501,O43852,P04062,O75340,Q9Y320,Q86YV9,O15269,O15460,O14967,P35613,Q03519,Q9H2J4,P48723,Q8N4V1,Q02818,P83881,P24390,Q01105,Q9BRR6,Q8IY95,Q9BRK5,O43464,Q5W0Z9,O95456,Q9H3N1,Q96G23,Q9BUN8,Q9Y217,Q15334,Q15041,Q9UNK0,P48651,Q9NWM8,Q9NZ08,Q8TCJ2,Q9UBU6,Q14257,O94979,O14880,Q8TB61,Q9BVK6,Q9BQE5,Q32P28,P80303,Q96AY3,Q15631,P27635,P49755,Q9Y678,Q96N66,Q07020,P26373,P27695,P50402,P83731,P01889,O75718,Q12907,Q96CS3,Q10472,P35606,Q969V3,P84095,P63241,P23396,Q15006,Q13217,O43681,P62266,P61106,P61803,Q9NR31,P18031,O95433,Q15738,Q9UNE7,Q9Y282,Q9Y4P3,Q8IXB1,P51809,P57088,P62847
Localization
GO Cellular component
msigdb_gocc
1,3,5,12,14,17,18,19,21,26,36,42,45,46,48,49,52,53,58,59,61,63,71,74,77,78,80,83,87,88,92,91,96,98,99,106,115,125,133,131,136,138,153,154,147,151,159,161,166,167,177,175,173,180,182,185,198,197,200,193,189,187,204,206,211,221,218,232,238,234,247,275,271,263,259,287,292,310,307,305,329,333,328,323,356,345,344,341,348,374,362,372,369,370,405,389,388,395,425,426,429,418,411,412,413
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2,453
Hydrolase
36
310
3.461169
0.000538
Q8NHP8,Q9HB40,P11117,O00584,Q9UIQ6,Q99538,P06280,Q9BTY2,P42892,P17900,Q8IV08,P50897,P10253,Q9H3G5,P06865,O75976,P15586,P16278,P42785,Q99519,Q92820,O14773,P10619,P07686,P38571,P54802,Q13510,P11233,P04062,P08236,Q9UQ84,Q99956,O00148,Q9Y6V7,Q05D32,Q9Y2L1
Functions
Protein Atlas Molecular function
protein_atlas_molecular_function
0,2,4,5,8,9,10,14,15,16,21,20,23,25,27,28,31,33,35,38,39,43,46,51,57,62,71,75,78,84,97,112,110,119,120,122
186,2346,110,1232,710,622,2347,663,5,43,2164,1922,1045,147,1740,362,798,1873,1639,2223,2419,1827,1779,1234,951,1877,588,665,28,2331,1172,904,214,715,716,78,10,27,2139,591,51,1692,84,1541,1010,23,46,1057,4,2022,75,483,2367,1882,1417,1544,2188,1695,31,33,1184,673,1698,16,389,1419,911,484,563,2190,1186,634,1837,1652,287,1929,762,1886,1887,1930,961,635,1307,1703,289,1889,913,1362,765,1935,2451,1791,57,1191,1192,2403,678,1428,1486,35,15,1936,727,1792,1749,1657,1793,917,1707,1554,1843,1121,20,368,457,1366,2030,2211,1892,1430,601,681,62,864,1612,1613,1794,564,491,1250,1614,293,1559,528,641,686,1070,1845,132,869,1433,814,1755,120,2172,1374,2173,2143,71,568,2230,494,1074,2175,219,607,1075,1757,1850,1711,1502,538,1712,377,495,1714,238,2147,417,1665,1944,1623,1269,1624,299,1326,1271,1507,693,352,1510,1902,980,1671,2037,1567,2125,1274,1030,2323,21,2284,400,1948,230,543,2150,1212,1276,1277,2344,2152,0,2041,647,1950,1569,933,613,39,1675,1979,1570,1571,1627,1724,1140,474,403,886,1388,653,2374,2129,1727,1144,38,9,252,1218,112,2044,1728,2156,1911,14,1033,2452,511,421,785,2200,2418,1683,2049,1286,1036,1578,992,1772,2071,25,1955,1524,840,938,2296,2182,1462,358,1092,1526,1915,2,2072,1287,2436,1094,939,1463,1773,2073,843,1038,2365,1982,2105,2379,1817,1820,1465,1863,1222,198,255,1348,8,1918,360,1157,1100,1866,2075,2381,97,177,1984,1160,1226,122,747,2076,585,146,1400,243,2238,1633,2291,119
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2,453
Ceramide metabolic process
9
14
3.15953
0.00158
Q99519,Q13510,P06280,P04062,P17900,P07686,O15269,O43464,P06865
Processes and pathways
GO Biological process
msigdb_gobp
38,71,10,78,16,51,88,147,27
88,147,1412,78,10,27,51,16,1189,71,1209,166,38,1465
1.4511688358424328,0.957569843538065,-0.14840819738674113,1.5877530843654364,5.112674566713143,3.74435860301373,2.8666565464518214,4.480069380026726,-0.03883864144469215,1.7892843924133246,-0.03883864144469215,0.9091852010520033,3.2640396895366344,-0.14840819738674113
2,453
Transporters
75
294
3.13448
0.001722
P61803,O14828,P05067,P24390,O75436,Q8IXU6,P08195,Q96N66,Q15287,Q9C0H2,P61421,P61916,Q14108,Q8IY95,P02786,Q9BRK5,Q07021,Q6NT16,P60903,P55011,P11279,Q5W0Z9,P11717,Q9H3N1,Q9Y639,Q15904,Q9BUN8,Q15758,Q8WY22,Q5J8M3,Q99720,P05556,Q99523,O15127,Q9NPA8,Q5BJF2,Q8NFH3,Q9H2J7,Q8WTV0,O15118,Q14849,Q8TCJ2,P00403,Q9UBU6,P05026,O94979,O43808,Q8TB61,P28288,P09132,O75340,P37198,Q93050,Q9Y320,P54709,Q5SRE5,Q9Y6C9,Q9H2D1,Q969V3,Q9UI26,Q6UW68,P35613,O15439,Q03519,P63241,Q658P3,Q15006,O60784,Q9UPT5,Q9Y4P1,Q96KP1,Q8N4V1,O43681,Q9H9B4,P49755
Functions
Protein Atlas Protein class
protein_atlas_protein_class
370,361,3,131,130,6,134,271,265,13,261,17,18,153,22,154,279,152,278,149,30,151,32,161,169,36,167,297,176,45,48,285,49,178,318,52,313,54,55,58,59,197,306,200,190,189,188,204,202,322,80,324,210,83,326,350,86,357,356,94,351,96,95,98,344,229,348,105,109,243,383,115,362,123,247
2222,518,1587,1738,1163,1688,622,2308,1871,663,2389,2205,361,1104,58,2390,178,554,1000,95,2376,362,1296,625,188,1591,2223,1297,1105,1001,1874,105,1537,2255,80,2079,754,130,1828,1538,665,1411,667,1478,1479,1642,1539,189,904,2242,1174,1175,388,1742,434,1644,306,1108,22,559,2349,629,1051,1645,1646,1299,190,3,630,285,1053,1744,1879,2186,134,2057,322,1926,1693,30,32,451,721,2400,672,452,910,2189,1746,725,2190,1651,1962,1239,856,131,202,1931,2115,96,2209,1935,861,324,807,1191,638,1060,1118,1604,1792,437,1993,2171,598,247,2274,1891,1843,1751,457,1122,2085,969,1892,1969,1065,326,149,1316,1612,412,2087,1893,278,1614,1754,261,1251,370,17,462,1254,644,344,1255,531,869,1709,814,817,1615,818,2435,98,279,2065,1896,1127,2382,1201,2383,2144,494,18,925,2386,59,926,348,265,826,297,36,1565,1265,2034,1666,52,45,2417,350,741,151,229,152,540,571,1029,351,1945,1805,2245,929,2284,6,153,1719,2364,2151,115,1446,1329,313,1138,2414,2152,2358,204,197,781,1515,443,55,981,176,884,1450,833,210,356,1083,507,1332,699,1086,652,383,271,1142,508,2399,49,2100,48,1861,154,1456,2046,2101,167,1147,1521,1148,1034,888,13,2102,839,357,54,2305,161,2160,123,1093,1815,787,788,1579,318,2447,1733,1527,1466,1774,1098,200,1153,2108,1583,844,1288,1467,1865,94,1396,407,2268,1530,1290,661,109,83,2184,1398,2018,243,1230,1959,751,793,169,86
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636,-0.6320109548770719,1.101222532398343,0.015351842220474437,-0.3440813155434071,0.17566672540232964,0.17566672540232964,-0.20380625761557572,0.5629592712307787,-5.217254591382774,-0.287669225677637,-0.1760557512169116,-0.14840819738674113,-0.31582532471033525,0.015351842220474437,0.8116357880463558,-0.011694963440921587,-0.573657045269454,-0.20380625761557572,0.14917574717760415,-0.06608047527750467,-0.14840819738674113,-0.3724366140244755,1.4052256408261132,-0.12086389363611108,0.46144338568076554,-0.8093110242796977,-0.1760557512169116,-0.06608047527750467,0.25461208410977504,1.242719326702117,1.5196912422366828,-0.6613290382750641,-0.12086389363611108,-0.4868395050717645,0.6881817808837658,-0.03883864144469215,-0.4294428411231804,0.2020690599158886,0.17566672540232964,0.9091852010520033,1.4969021778921914
2,453
Glycosphingolipid metabolism
8
14
3.132934
0.001731
P16278,Q99519,Q13510,P06280,P10619,P17900,P07686,P06865
Processes and pathways
Reactome Pathways
msigdb_reactome
33,38,71,10,46,16,51,27
2222,362,78,10,27,51,46,33,16,71,38,1456,1465,1466
-0.7498418476188665,0.48693710960367753,1.5877530843654364,5.112674566713143,3.74435860301373,2.8666565464518214,2.967179422029158,3.515947665912546,4.480069380026726,1.7892843924133246,3.2640396895366344,-0.14840819738674113,-0.14840819738674113,-0.14840819738674113
2,453
Lysosomal lumen
22
30
3.002348
0.002679
Q8NHP8,P11117,O00584,Q99538,P06280,P17900,P61916,Q14108,Q8IV08,P50897,P10253,P06865,P15586,P16278,Q99519,O14773,P10619,P07686,P38571,P54802,Q13510,P04062
Localization
GO Cellular component
msigdb_gocc
0,4,5,9,10,16,17,18,21,20,23,27,31,33,38,43,46,51,57,62,71,78
5,43,362,78,10,27,51,1692,84,23,46,4,2022,31,33,16,1485,57,20,62,17,71,18,21,2004,0,38,9,1090,1466
5.3520399209533815,3.0071633344987623,0.48693710960367753,1.5877530843654364,5.112674566713143,3.74435860301373,2.8666565464518214,-0.287669225677637,1.4969021778921914,4.171950719968975,2.967179422029158,5.369004334201069,-0.515682880321347,3.6306313072401735,3.515947665912546,4.480069380026726,-0.1760557512169116,2.5393209088333624,4.281433897456435,2.223991046325372,4.480069380026726,1.7892843924133246,4.444149955886005,4.281433897456435,-0.4868395050717645,6.357189361817599,3.2640396895366344,5.249884528644196,0.015351842220474437,-0.14840819738674113
2,453
Host cell receptor for virus entry
7
14
2.996926
0.002727
Q14108,Q9Y624,P02786,Q8WTV0,O15118,P11279,P35613
Functions
Protein Atlas Molecular function
protein_atlas_molecular_function
18,50,22,55,58,30,96
58,22,285,1053,1055,1832,30,1695,96,18,297,55,102,50
2.5185627027049047,4.24503039697022,0.5881497579803545,0.015351842220474437,0.015351842220474437,-0.3724366140244755,3.6686452238951888,-0.287669225677637,1.3590690210496719,4.444149955886005,0.5881497579803545,2.6631141752887224,1.2894258439182555,2.886826237557072
2,453
Exogenous protein binding
7
14
2.996926
0.002727
Q14108,Q9Y624,P02786,Q8WTV0,O15118,P11279,P35613
Functions
GO Molecular function
msigdb_gomf
18,50,22,55,58,30,96
58,22,285,1053,1055,1832,30,1695,96,18,297,55,102,50
2.5185627027049047,4.24503039697022,0.5881497579803545,0.015351842220474437,0.015351842220474437,-0.3724366140244755,3.6686452238951888,-0.287669225677637,1.3590690210496719,4.444149955886005,0.5881497579803545,2.6631141752887224,1.2894258439182555,2.886826237557072
2,453
Vesicle mediated transport
63
252
2.987243
0.002815
Q9Y678,P05067,P24390,O75436,P51148,P15531,O14828,Q9NR31,Q08380,O75503,Q15286,Q14108,A4D1P6,P18031,P50897,P02786,Q99747,Q9BRK5,P60903,Q06481,Q9H269,P11279,Q9Y282,P11717,Q9Y3E7,Q15904,P40616,P61020,Q9Y217,P27695,Q15334,P05556,Q99523,O15127,Q9UNK0,Q8WTV0,O15118,Q14849,P51790,Q12907,Q92572,O94979,Q13501,Q8NC96,P11233,Q9BVK6,P35606,O75340,Q86Y82,Q7Z392,O15439,P84095,P54920,O60784,Q6IAA8,Q9UPT5,Q96KP1,Q9UHY1,P83436,Q96AX1,P61163,P49755,P61106
Processes and pathways
GO Biological process
msigdb_gobp
275,3,131,130,368,135,361,405,11,12,264,18,139,389,20,22,282,154,278,26,422,30,426,32,428,36,165,293,177,287,175,285,49,178,180,55,58,59,60,329,332,189,74,76,75,206,323,80,354,353,95,345,343,105,241,109,383,117,237,250,249,247,369
2222,139,1233,2239,622,2308,430,361,1536,1403,58,2390,178,554,555,95,556,1405,1296,587,1825,2271,1297,1105,1001,2207,2112,2137,105,1171,80,1779,849,130,12,951,1477,667,1539,189,1005,1174,589,2448,1050,956,1742,22,2349,1052,3,285,1744,592,1594,1542,1832,2022,75,30,32,1885,135,910,389,960,563,1962,131,1928,287,858,2026,1361,1748,435,860,764,2208,1934,323,1790,1655,165,1603,1060,1116,1792,966,1119,1993,2171,247,2409,1120,862,1843,20,1751,368,457,1491,1122,60,411,1557,1658,1752,343,1612,1367,278,491,1432,1196,293,1559,369,249,1369,1318,686,415,1070,1254,1255,237,345,1846,1615,1996,1371,1895,26,464,11,870,2382,1200,329,1562,1204,74,2385,1973,18,1500,2120,1379,2386,59,1976,1620,1323,264,175,875,36,1440,1665,1131,1505,2417,497,741,241,1506,1210,353,1077,694,354,2439,1857,930,1444,1328,2004,1721,76,2152,55,2069,2153,1673,1215,1448,332,2388,1571,1724,250,699,2263,383,1143,508,2399,1678,475,49,282,1768,655,615,154,206,2267,1034,616,1459,992,1149,422,1150,1220,787,2103,405,1345,790,2107,1774,1224,619,1775,2289,1098,2407,117,1865,791,2109,1397,2053,944,1919,1734,180,661,109,177,1471,426,2298,1398,428,2018,1959,2356,275,1823
-0.7498418476188665,0.9816668449808295,-0.06608047527750467,-0.7795306887569614,0.25461208410977504,-0.9595690419277156,0.41022127826622157,0.48693710960367753,-0.20380625761557572,-0.14840819738674113,2.5185627027049047,-1.3919365530823733,0.8605422247461364,0.30681317218691295,0.30681317218691295,1.3590690210496719,0.30681317218691295,-0.14840819738674113,-0.0934217780812221,0.2807548615748546,-0.3724366140244755,-0.8391823888505335,-0.0934217780812221,-0.011694963440921587,0.0423030303136774,-0.7202449724403305,-0.6027867889099643,-0.6320109548770719,1.242719326702117,-0.03883864144469215,1.5196912422366828,-0.3440813155434071,0.12259502497299368,1.0296732296083115,5.043629738470276,0.06915982780459791,-0.1760557512169116,0.22838382789555492,-0.20380625761557572,0.8116357880463558,0.0423030303136774,-0.03883864144469215,0.2807548615748546,-5.96721793340267,0.015351842220474437,0.06915982780459791,-0.31582532471033525,4.24503039697022,-1.1120471207717453,0.015351842220474437,5.8371756458828,0.5881497579803545,-0.31582532471033525,0.2807548615748546,-0.23165908496291274,-0.20380625761557572,-0.3724366140244755,-0.515682880321347,1.6778049667911492,3.6686452238951888,3.535129278103945,-0.4008906448040487,1.005701108892365,0.09592343471852349,0.46144338568076554,0.06915982780459791,0.30681317218691295,-0.4580926446081327,1.0296732296083115,-0.4294428411231804,0.5881497579803545,0.12259502497299368,-0.515682880321347,-0.12086389363611108,-0.31582532471033525,0.41022127826622157,0.12259502497299368,0.17566672540232964,-0.7202449724403305,-0.4294428411231804,0.5376942136598729,-0.3440813155434071,-0.25961361162023794,0.9091852010520033,-0.23165908496291274,0.015351842220474437,-0.011694963440921587,-0.3440813155434071,0.06915982780459791,-0.011694963440921587,-0.4868395050717645,-0.6613290382750641,0.6632817213848923,-1.6143034879767137,-0.011694963440921587,0.12259502497299368,-0.3724366140244755,4.281433897456435,-0.31582532471033525,0.48693710960367753,0.3844911176822035,-0.1760557512169116,-0.011694963440921587,2.414217620077897,0.4358717352001903,-0.20380625761557572,-0.25961361162023794,-0.31582532471033525,0.5123537700339801,-0.23165908496291274,-0.12086389363611108,0.6132664740350646,0.3586803384631244,-0.14840819738674113,-0.03883864144469215,0.5881497579803545,-0.20380625761557572,0.48693710960367753,0.6632817213848923,-0.12086389363611108,-0.0934217780812221,0.22838382789555492,0.4358717352001903,0.015351842220474437,-0.06608047527750467,-0.06608047527750467,0.6881817808837658,0.5123537700339801,-0.3724366140244755,-0.23165908496291274,-0.4868395050717645,-0.12086389363611108,-0.4008906448040487,3.9318558675678688,0.3844911176822035,5.095441173333071,0.12259502497299368,-1.3291467261308327,-0.03883864144469215,0.5376942136598729,-0.20380625761557572,-0.03883864144469215,1.7001960684604143,-1.3291467261308327,-0.4580926446081327,4.444149955886005,-0.1760557512169116,-0.6027867889099643,-0.12086389363611108,-1.3291467261308327,2.4977678795050133,-0.4580926446081327,-0.23165908496291274,-0.0934217780812221,0.6383102048089089,0.8848963209599016,0.12259502497299368,3.419625726577343,-0.14840819738674113,-0.25961361162023794,-0.011694963440921587,-0.1760557512169116,-1.743154580938761,0.3586803384631244,0.2020690599158886,0.6881817808837658,-0.1760557512169116,-0.03883864144469215,0.5123537700339801,0.015351842220474437,0.22838382789555492,0.5123537700339801,-2.7141309997253065,-0.3724366140244755,0.09592343471852349,-0.14840819738674113,-0.0934217780812221,-0.4868395050717645,-0.287669225677637,1.6778049667911492,-0.6320109548770719,2.6631141752887224,-0.5446222359725705,-0.6320109548770719,-0.25961361162023794,-0.03883864144469215,-0.14840819738674113,0.5376942136598729,-1.3291467261308327,-0.20380625761557572,-0.287669225677637,0.6632817213848923,0.22838382789555492,-0.8093110242796977,0.48693710960367753,-0.011694963440921587,0.3586803384631244,-1.4550592541183711,-0.25961361162023794,0.3844911176822035,2.9270675607263192,0.6132664740350646,-0.31582532471033525,0.25461208410977504,0.2807548615748546,0.957569843538065,0.7870821214860848,-0.8093110242796977,0.0423030303136774,0.2807548615748546,-0.14840819738674113,0.06915982780459791,-0.011694963440921587,0.4358717352001903,-0.011694963440921587,-0.03883864144469215,0.17566672540232964,-0.573657045269454,0.46144338568076554,-0.0934217780812221,0.17566672540232964,-0.573657045269454,-0.31582532471033525,-0.03883864144469215,0.2807548615748546,-0.31582532471033525,-0.8691443232390553,0.015351842220474437,-1.582291761318393,1.1722330401086165,-0.3724366140244755,0.17566672540232964,-0.573657045269454,-0.12086389363611108,-0.515682880321347,0.09592343471852349,-0.4008906448040487,-0.287669225677637,0.8605422247461364,0.25461208410977504,1.242719326702117,0.8848963209599016,-0.14840819738674113,0.4358717352001903,-0.89919637419257,-0.12086389363611108,0.4358717352001903,-0.4868395050717645,-0.4294428411231804,-1.1120471207717453,0.6383102048089089,-0.3440813155434071
2,453
Glycoside hydrolase superfamily [IPR017853]
9
14
2.967943
0.002998
P16278,P06280,P04062,Q9BTY2,P07686,P08236,P10253,P06865,P54802
Sequence
InterPro Superfamily
interpro_homologous_superfamily
33,10,78,14,51,84,23,27,62
2419,78,10,27,51,134,84,23,33,765,62,1711,14,1090
-1.77556674425155,1.5877530843654364,5.112674566713143,3.74435860301373,2.8666565464518214,1.005701108892365,1.4969021778921914,4.171950719968975,3.515947665912546,0.17566672540232964,2.223991046325372,-0.287669225677637,4.658398490383113,0.015351842220474437
2,453
Glycosidase
9
15
2.937336
0.00331
P16278,Q99519,P06280,Q9BTY2,P04062,P07686,P10253,P06865,P54802
Functions
Protein Atlas Molecular function
protein_atlas_molecular_function
33,38,10,14,78,51,23,27,62
1740,2419,78,10,27,51,84,23,33,765,62,2230,1711,38,14
-0.31582532471033525,-1.77556674425155,1.5877530843654364,5.112674566713143,3.74435860301373,2.8666565464518214,1.4969021778921914,4.171950719968975,3.515947665912546,0.17566672540232964,2.223991046325372,-0.7498418476188665,-0.287669225677637,3.2640396895366344,4.658398490383113
2,453
Spasticity
29
237
2.928492
0.003406
P11117,O00584,Q01105,O75503,P17900,P61916,Q15392,Q9P032,P50897,Q9Y487,O43464,P55011,P16278,O43505,Q99519,Q15056,Q15041,Q99720,P07686,O15118,P35270,O94979,Q13510,Q13501,Q8NC96,P04062,O60701,Q9Y320,Q5XKP0
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
4,5,136,12,16,17,19,156,20,158,147,149,33,37,38,174,173,48,51,58,69,189,71,74,76,78,207,83,108
1401,1736,1737,1738,622,553,663,5,711,58,2254,1590,2402,147,37,362,319,2223,2432,207,2423,901,714,520,754,1234,902,12,1538,588,1642,189,904,1174,1480,717,957,1006,755,1108,78,2292,591,51,720,1782,1300,1054,1541,1543,521,2082,4,1238,1885,33,2391,16,1419,2189,1421,484,1834,2301,1962,1239,2060,456,1241,1783,1702,1245,1931,1787,764,962,69,323,766,2209,767,1935,324,807,2403,1550,1890,1116,1117,2028,2273,1705,2404,1553,1247,1840,1841,1891,1842,1707,1554,20,1751,2312,1556,1314,863,2227,1557,1315,1558,149,1612,1613,1431,209,867,17,371,295,2118,1198,327,1615,1996,136,2195,1376,1998,2033,1562,1563,1797,1618,74,71,2119,537,2120,1322,376,2176,736,173,1323,1803,174,377,19,1027,1265,877,928,1383,692,1666,2067,469,878,497,108,240,1759,1135,2214,1945,742,695,1512,543,1213,1720,1276,2040,2344,1858,1721,76,1278,648,2388,504,1979,505,1333,474,2263,1766,251,2286,383,1517,271,1980,1810,1144,38,1454,48,1145,2045,2049,1523,1912,2338,2162,1391,704,514,515,2106,1983,2252,1466,156,1864,1152,1583,2074,1529,580,2220,1289,425,2381,661,1471,83,998,708,1400,158,429,1162,2238,946,793
-0.14840819738674113,-0.31582532471033525,-0.31582532471033525,-0.31582532471033525,0.25461208410977504,0.30681317218691295,0.22838382789555492,5.3520399209533815,0.2020690599158886,2.5185627027049047,-0.8093110242796977,-0.23165908496291274,-1.5503611285496142,0.957569843538065,3.342062664558531,0.48693710960367753,0.5376942136598729,-0.7498418476188665,-2.304710296068787,0.762460586097164,-2.0376854596970393,0.09592343471852349,0.2020690599158886,0.33278800733023756,0.17566672540232964,-0.06608047527750467,0.09592343471852349,5.043629738470276,-0.20380625761557572,0.2807548615748546,-0.25961361162023794,0.8116357880463558,0.09592343471852349,-0.03883864144469215,-0.1760557512169116,0.2020690599158886,0.06915982780459791,0.0423030303136774,0.17566672540232964,-0.011694963440921587,1.5877530843654364,-0.89919637419257,0.2807548615748546,2.8666565464518214,0.2020690599158886,-0.3440813155434071,-0.0934217780812221,0.015351842220474437,-0.20380625761557572,-0.20380625761557572,0.33278800733023756,-0.573657045269454,5.369004334201069,-0.06608047527750467,-0.4008906448040487,3.515947665912546,-1.3919365530823733,4.480069380026726,-0.14840819738674113,-0.690740541170887,-0.14840819738674113,0.3586803384631244,-0.3724366140244755,-0.9293380943113951,-0.4580926446081327,-0.06608047527750467,-0.5446222359725705,0.3844911176822035,-0.06608047527750467,-0.3440813155434071,-0.287669225677637,-0.06608047527750467,-0.4294428411231804,-0.3440813155434071,0.17566672540232964,0.06915982780459791,1.8114392882780097,0.5376942136598729,0.17566672540232964,-0.7202449724403305,0.17566672540232964,-0.4294428411231804,0.5376942136598729,0.14917574717760415,-1.5503611285496142,-0.20380625761557572,-0.4008906448040487,-0.011694963440921587,-0.011694963440921587,-0.515682880321347,-0.8391823888505335,-0.287669225677637,-1.582291761318393,-0.20380625761557572,-0.06608047527750467,-0.3724366140244755,-0.3724366140244755,-0.4008906448040487,-0.3724366140244755,-0.287669225677637,-0.20380625761557572,4.281433897456435,-0.31582532471033525,-0.9595690419277156,-0.20380625761557572,-0.0934217780812221,0.12259502497299368,-0.7498418476188665,-0.20380625761557572,-0.0934217780812221,-0.20380625761557572,0.957569843538065,-0.23165908496291274,-0.23165908496291274,-0.14840819738674113,0.762460586097164,0.12259502497299368,4.480069380026726,0.48693710960367753,0.5881497579803545,-0.6027867889099643,-0.03883864144469215,0.5376942136598729,-0.23165908496291274,-0.4868395050717645,1.005701108892365,-0.690740541170887,-0.12086389363611108,-0.4868395050717645,-0.515682880321347,-0.20380625761557572,-0.20380625761557572,-0.3440813155434071,-0.23165908496291274,1.7001960684604143,1.7892843924133246,-0.6027867889099643,0.33278800733023756,-0.6027867889099643,-0.0934217780812221,0.48693710960367753,-0.6613290382750641,0.2020690599158886,0.8848963209599016,-0.0934217780812221,-0.3440813155434071,0.8848963209599016,0.48693710960367753,4.390108836903907,0.0423030303136774,-0.06608047527750467,0.12259502497299368,0.09592343471852349,-0.12086389363611108,0.22838382789555492,-0.25961361162023794,-0.5446222359725705,0.3844911176822035,0.12259502497299368,0.3586803384631244,1.242719326702117,0.6881817808837658,-0.31582532471033525,-0.011694963440921587,-0.7202449724403305,-0.4294428411231804,0.2020690599158886,0.22838382789555492,-0.1760557512169116,0.33278800733023756,-0.03883864144469215,-0.287669225677637,-0.06608047527750467,-0.515682880321347,-1.0813764681271592,-0.3724366140244755,-0.287669225677637,1.6778049667911492,-0.06608047527750467,0.25461208410977504,-1.3291467261308327,0.3586803384631244,-0.4580926446081327,0.3586803384631244,-0.0934217780812221,0.3844911176822035,-0.8093110242796977,-0.31582532471033525,0.6632817213848923,-0.8691443232390553,0.48693710960367753,-0.1760557512169116,0.6383102048089089,-0.4580926446081327,-0.3440813155434071,-0.011694963440921587,3.2640396895366344,-0.14840819738674113,2.9471395788264925,-0.011694963440921587,-0.515682880321347,-0.515682880321347,-0.1760557512169116,-0.4008906448040487,-1.0507929166127075,-0.6320109548770719,-0.12086389363611108,0.22838382789555492,0.3586803384631244,0.3586803384631244,-0.573657045269454,-0.4580926446081327,-0.7795306887569614,-0.14840819738674113,0.957569843538065,-0.3724366140244755,-0.011694963440921587,-0.20380625761557572,-0.5446222359725705,-0.1760557512169116,0.30681317218691295,-0.7202449724403305,-0.06608047527750467,0.4358717352001903,-1.2978775635186959,0.25461208410977504,-0.14840819738674113,1.5196912422366828,0.06915982780459791,0.22838382789555492,-0.12086389363611108,0.957569843538065,0.4358717352001903,-0.011694963440921587,-0.7498418476188665,0.09592343471852349,0.17566672540232964
2,453
Hypertonia
31
287
2.891971
0.003828
P05067,P11117,O00584,Q01105,O75503,P17900,P61916,Q15392,Q9P032,P50897,Q9Y487,O43464,P06865,P55011,P16278,O43505,Q99519,P31930,Q14739,Q15056,Q99720,P07686,Q9UBM7,O15118,P35270,Q13510,Q13501,Q8NC96,P04062,Q9Y320,Q5XKP0
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
3,4,5,136,12,16,17,19,156,20,158,147,27,149,33,37,38,164,42,174,48,51,53,58,69,71,74,76,78,83,108
1401,1736,1737,1738,622,553,1921,663,5,711,58,2254,1590,2402,147,37,362,319,797,1475,2223,1407,2432,207,2423,901,557,714,520,754,1234,902,12,1538,588,1642,189,904,1174,1480,715,717,1644,1357,957,1006,755,1108,78,1051,3,1178,2080,27,2292,591,51,720,1782,1300,1054,1541,1543,521,1302,2187,2082,4,451,1238,1885,365,33,2391,16,1419,2189,1650,1421,484,1834,2301,1962,1239,2060,456,1241,1783,1702,1245,1931,164,1787,764,962,69,323,766,2209,767,1935,324,807,2403,1193,1550,1890,1116,1117,2028,1992,2273,1705,2404,1553,1247,1840,1841,1891,1842,1707,1554,2116,20,1751,2312,1556,1314,863,970,2227,599,1557,1315,1558,149,1612,1613,865,1431,209,2087,867,458,17,371,295,2118,1198,327,1615,1996,136,1320,1373,2195,464,1376,1998,2033,1562,1563,1797,1618,74,71,2119,537,2120,1322,376,2176,42,736,173,1323,1803,174,824,377,19,1027,1265,1441,877,928,1383,692,1666,2067,469,878,497,108,240,1759,2096,1135,2214,2321,1945,742,695,1512,543,1213,1720,1276,2040,1446,2344,1858,1721,76,1278,2041,981,648,2388,504,1979,505,1333,474,2263,2008,1766,251,2286,383,1517,271,508,2399,1980,1810,1144,38,1454,48,1218,1861,1145,2045,1729,656,2049,1523,1912,1814,2338,2162,1815,1391,704,514,515,2106,1983,1465,2252,1466,156,1864,1152,53,1583,2074,1529,580,2220,1289,425,2381,661,2297,1471,83,998,708,1400,158,429,1162,2238,946,793
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2,453
Organelle subcompartment
44
278
2.879817
0.003979
Q6UXD5,P05067,P24390,Q9BRR6,Q14108,Q15392,Q8IV08,O43464,P11717,Q9H3N1,Q96G23,Q15904,Q9BUN8,P40616,Q14739,Q5J8M3,Q15334,Q99720,Q15041,Q99523,O15127,Q5BJF2,Q9UBM7,Q9UNK0,P48651,Q9NZ08,Q14849,Q8TCJ2,P10321,Q9UBU6,O00461,O94979,O14880,Q8TB61,Q9BVK6,O43852,P04062,O75340,Q9Y320,O15269,O14967,P35613,Q03519,Q8N4V1
Localization
GO Cellular component
msigdb_gocc
1,3,131,138,18,19,21,147,32,161,166,36,167,165,42,45,175,48,173,49,178,52,53,180,182,198,59,197,63,200,67,189,187,204,206,77,78,80,83,88,91,96,98,115
2222,2078,621,1738,622,67,2240,1872,2348,361,187,91,1403,2390,178,88,1405,2402,147,1296,1825,77,1591,1476,2272,1640,2423,2137,1171,80,849,665,1411,1478,2185,1642,189,1005,1174,1412,589,2448,1050,1593,957,307,78,629,1645,1646,3,1053,2139,1989,592,1542,63,32,2025,1183,910,389,1596,1962,1013,1836,131,524,858,2026,961,1306,1547,1839,595,525,1784,323,96,914,1485,638,165,726,770,1792,437,966,2261,182,1119,1993,2171,598,247,292,1843,1491,1313,1122,1556,411,2085,1557,1658,1752,1612,412,1893,491,1432,1250,1196,1559,369,640,528,1251,370,1369,414,1070,344,1845,237,345,1615,1071,1072,2088,2435,98,2212,2065,1375,871,328,2382,1998,2383,329,2144,1259,2230,18,1025,569,1662,42,2304,59,926,538,348,173,1323,1663,175,19,875,826,395,36,1382,1665,828,52,45,2417,497,1384,2095,2328,1506,1625,1507,571,1,880,2397,2322,1512,21,930,1079,543,1276,115,780,1446,471,2152,2358,204,1214,197,2041,647,1515,1673,1215,2154,1448,1450,506,356,1083,507,1332,333,166,652,2264,1910,271,2399,1336,49,48,2406,987,837,211,138,1089,1456,167,1147,1521,206,1090,1034,2047,616,839,992,1912,161,1684,787,788,704,1579,548,1732,1981,1527,843,1465,2252,198,891,1774,1581,619,1775,2289,53,200,2108,1288,845,791,1290,180,2202,582,426,83,2340,1473,1398,1399,429,709,2356,275,895
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2,453
Cherry red spot of the macula
6
9
2.872225
0.004076
P16278,Q99519,P10619,P17900,P07686,P06865
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
33,38,46,16,51,27
27,51,46,1238,33,16,71,38,1466
3.74435860301373,2.8666565464518214,2.967179422029158,-0.06608047527750467,3.515947665912546,4.480069380026726,1.7892843924133246,3.2640396895366344,-0.14840819738674113
2,453
Lytic vacuole organization
8
18
2.810575
0.004945
P11117,O14773,O75503,Q14108,P07686,P50897,P10253,P54802
Processes and pathways
GO Biological process
msigdb_gobp
4,43,12,18,51,20,23,62
2239,43,12,78,51,23,4,726,20,457,62,369,18,241,250,508,1224,428
-0.7795306887569614,3.0071633344987623,5.043629738470276,1.5877530843654364,2.8666565464518214,4.171950719968975,5.369004334201069,0.2020690599158886,4.281433897456435,0.3844911176822035,2.223991046325372,0.48693710960367753,4.444149955886005,0.6881817808837658,0.6632817213848923,0.3586803384631244,-0.03883864144469215,0.4358717352001903
2,453
Hydrolase activity hydrolyzing o glycosyl compounds
10
18
2.802529
0.00507
P16278,Q99519,P06280,Q9BTY2,P04062,P17900,P07686,P10253,P06865,P54802
Functions
GO Molecular function
msigdb_gomf
33,38,10,14,78,16,51,23,27,62
2419,78,10,27,51,84,23,33,16,765,62,2230,1711,1030,38,14,2365,1820
-1.77556674425155,1.5877530843654364,5.112674566713143,3.74435860301373,2.8666565464518214,1.4969021778921914,4.171950719968975,3.515947665912546,4.480069380026726,0.17566672540232964,2.223991046325372,-0.7498418476188665,-0.287669225677637,0.0423030303136774,3.2640396895366344,4.658398490383113,-1.1736480958785238,-0.3440813155434071
2,453
Aminoglycan metabolic process
6
12
2.799654
0.005116
P16278,O43505,P07686,P06865,P54802,P15586
Processes and pathways
GO Biological process
msigdb_gobp
33,37,51,27,62,31
37,207,1742,27,51,84,31,33,62,1615,1257,379
3.342062664558531,0.762460586097164,-0.31582532471033525,3.74435860301373,2.8666565464518214,1.4969021778921914,3.6306313072401735,3.515947665912546,2.223991046325372,-0.23165908496291274,-0.06608047527750467,0.48693710960367753
2,453
Membrane lipid catabolic process
7
11
2.798074
0.005141
Q99519,Q13510,P06280,P17900,P07686,P50897,P06865
Processes and pathways
GO Biological process
msigdb_gobp
38,71,10,16,51,20,27
1412,78,10,27,51,16,20,71,38,2406,1465
-0.14840819738674113,1.5877530843654364,5.112674566713143,3.74435860301373,2.8666565464518214,4.480069380026726,4.281433897456435,1.7892843924133246,3.2640396895366344,-1.582291761318393,-0.14840819738674113
2,453
Sphingolipid metabolic process
11
22
2.76794
0.005641
P16278,Q99519,Q13510,P06280,P04062,P17900,P07686,P50897,O15269,O43464,P06865
Processes and pathways
GO Biological process
msigdb_gobp
33,38,71,10,78,16,51,20,88,147,27
88,147,1412,78,10,27,51,33,16,1013,1189,20,2212,71,1209,166,38,1465,2252,1466,891,1774
1.4511688358424328,0.957569843538065,-0.14840819738674113,1.5877530843654364,5.112674566713143,3.74435860301373,2.8666565464518214,3.515947665912546,4.480069380026726,0.0423030303136774,-0.03883864144469215,4.281433897456435,-0.7202449724403305,1.7892843924133246,-0.03883864144469215,0.9091852010520033,3.2640396895366344,-0.14840819738674113,-0.7795306887569614,-0.14840819738674113,0.12259502497299368,-0.31582532471033525
2,453
Glycosaminoglycan metabolism
6
11
2.759521
0.005789
P16278,O43505,P07686,P06865,P54802,P15586
Processes and pathways
Reactome Pathways
msigdb_reactome
33,37,51,27,62,31
1047,37,27,51,84,31,33,62,379,204,580
0.015351842220474437,3.342062664558531,3.74435860301373,2.8666565464518214,1.4969021778921914,3.6306313072401735,3.515947665912546,2.223991046325372,0.48693710960367753,0.7870821214860848,0.30681317218691295
2,453
Tchem
27
261
2.758546
0.005806
P05067,Q9UIQ6,Q99538,Q9BTY2,P42892,P06865,P11717,P16278,P35790,P42785,Q15904,Q92820,Q15375,P10619,Q99523,P07686,Q5BJF2,Q9UBM7,Q9H2J7,Q8WTV0,P38571,P51790,Q13510,P04062,P08236,O15269,O75874
Drugs and Diseases
Pharos IDG Category
pharos_protein_category
3,8,9,14,15,27,32,33,34,35,36,39,44,46,49,51,52,53,54,55,57,60,71,78,84,88,93
897,1738,663,1535,1872,947,1536,1044,88,1589,2431,95,712,1740,1591,1407,2419,2136,1640,951,93,1172,1412,716,2113,140,1357,755,1109,78,1176,1177,906,1051,1007,3,1053,1780,1781,1110,27,2139,1414,1358,591,51,1782,1692,2186,84,2057,1300,1542,521,1010,46,2022,1927,32,851,1011,483,1111,722,1544,408,2188,364,1884,1694,2025,1695,2434,33,286,673,389,1650,1834,523,2190,1360,632,1186,2351,634,2060,1990,1423,1241,1598,246,1305,287,1929,961,635,1306,763,2282,1839,1244,525,435,1703,1114,289,1785,487,764,34,2451,914,2191,57,638,1192,2170,769,1603,1550,1060,35,1116,15,809,1118,1936,915,1312,1657,2352,2261,291,1793,1605,1843,1121,2116,1366,2030,2312,60,863,1493,1016,2227,2031,1248,1968,1969,601,1315,2142,681,1612,2194,1794,1431,1367,564,491,1066,641,415,922,1938,2413,1021,869,1433,1846,2275,1372,125,346,172,1847,924,2195,2196,2430,1616,2302,1941,1756,312,1798,1799,1564,2303,71,691,160,2144,1259,976,1662,1850,1711,1803,174,194,127,44,1713,2437,739,297,36,876,1382,1665,349,52,1944,1507,571,2321,1272,2125,1806,1030,1672,502,1276,781,55,39,1724,2043,653,574,1677,49,9,476,1575,14,2452,510,2267,1460,54,1955,2182,841,2050,1463,2280,198,1582,2289,53,338,8,1918,1471,256,1292,1633
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2,453
Nuclear outer membrane endoplasmic reticulum membrane network
36
238
2.701306
0.006907
Q6UXD5,P24390,Q9BRR6,Q14108,Q15392,Q8IV08,O43464,Q9H3N1,Q96G23,Q15904,Q9BUN8,Q14739,Q5J8M3,Q15041,Q99720,Q99523,Q5BJF2,Q9UBM7,P48651,Q9NZ08,Q14849,Q8TCJ2,P10321,Q9UBU6,O94979,O14880,Q8TB61,Q9BVK6,O43852,O75340,Q9Y320,O15269,O14967,P35613,Q03519,Q8N4V1
Localization
GO Cellular component
msigdb_gocc
1,131,138,18,19,21,147,161,166,36,167,42,45,173,48,49,52,53,182,198,59,197,63,200,189,187,204,206,77,80,83,88,91,96,98,115
2222,2078,621,1738,622,2240,1872,2348,187,91,1104,1403,88,1405,2402,147,77,1591,1476,2272,1640,2423,80,849,665,1411,1478,2185,1642,189,1005,1174,1412,589,2448,1050,1593,957,307,629,1645,1646,1053,1781,2139,1989,592,1542,63,2025,1183,910,389,1596,1013,1836,131,524,858,2026,1306,1547,1839,595,525,1784,323,96,914,1485,638,726,1890,770,437,966,2261,182,1119,1993,2171,598,247,1891,292,1313,1122,1556,411,2085,1557,1658,1752,1612,412,1893,491,1250,1196,1559,369,640,528,1251,370,1369,1252,414,1070,344,1845,345,1072,2088,2435,98,2212,2065,871,328,2383,329,2144,1259,2230,18,1025,569,1662,42,59,538,348,173,1323,1663,19,875,826,395,36,1382,828,52,45,2417,1384,2328,1506,1625,1507,571,1,880,2397,2322,1512,21,1079,543,1276,115,780,1446,471,2152,2358,204,1214,197,2041,647,1515,1673,2154,1450,506,356,1083,1332,333,166,652,2264,1910,271,2399,1336,49,48,2406,987,211,138,1089,1456,167,1147,1521,206,2047,839,992,1912,161,1684,787,788,704,1579,1732,1527,843,1465,2252,198,891,1774,1581,619,1775,2289,53,200,2108,1288,845,1290,2202,426,83,2340,1398,1399,429,709,275,895
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2,453
Abnormality of coordination
27
252
2.699798
0.006938
P05067,O00584,Q01105,O75503,Q9Y3E5,P61916,Q14108,Q9P032,Q8IV08,P50897,P16278,Q99519,O14773,Q99720,P07686,O15118,P35270,Q13510,Q13501,Q8NC96,P04062,O75340,Q12824,O15460,Q92974,Q14738,Q5XKP0
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
3,5,136,12,146,17,18,156,21,20,33,38,43,48,51,58,69,71,74,76,78,80,85,92,100,107,108
898,1737,622,553,1921,5,43,711,479,58,2254,92,2402,1741,362,319,797,2223,2432,2423,557,2255,714,520,80,754,1234,902,12,1478,1172,904,905,2242,1480,2166,715,1412,716,2056,956,717,1644,482,1743,306,1006,1109,307,78,559,3,909,1960,2292,591,631,51,1782,1054,1543,2187,1881,2350,1011,451,1111,1238,33,2391,1419,758,1650,1421,484,1834,2301,1239,2060,456,1241,1598,234,1783,1702,1245,1931,288,1787,962,2169,69,766,2209,767,1790,1791,324,807,2170,1426,1060,1890,1116,1117,1966,966,2273,1793,1247,1488,1840,1842,1554,2116,20,2312,1123,1314,1610,1315,1558,1612,1708,1613,865,2087,491,17,371,492,2118,1198,1319,1615,1996,136,1320,2229,1373,2195,2196,464,1998,85,1797,374,567,74,71,821,280,18,1322,2176,107,220,1803,174,824,1804,1664,1027,877,1028,692,1944,2067,2415,108,1667,240,1271,1135,2321,1671,353,2178,694,742,695,2068,929,21,543,1213,1720,1276,780,1721,76,2005,1214,831,1215,2285,1979,505,100,2317,506,935,1333,699,2263,419,316,2286,2235,508,2399,1336,1337,2129,38,1860,1454,48,1681,837,1861,1145,1520,616,2338,445,659,2447,1733,2106,1983,1818,1819,1820,198,1466,156,1864,1152,2074,580,791,1289,425,1228,146,158,429,1162,2238,793,1778
0.09592343471852349,-0.31582532471033525,0.25461208410977504,0.30681317218691295,-0.4294428411231804,5.3520399209533815,3.0071633344987623,0.2020690599158886,0.3586803384631244,2.5185627027049047,-0.8093110242796977,1.4052256408261132,-1.5503611285496142,-0.31582532471033525,0.48693710960367753,0.5376942136598729,0.14917574717760415,-0.7498418476188665,-2.304710296068787,-2.0376854596970393,0.30681317218691295,-0.8093110242796977,0.2020690599158886,0.33278800733023756,1.5196912422366828,0.17566672540232964,-0.06608047527750467,0.09592343471852349,5.043629738470276,-0.1760557512169116,-0.03883864144469215,0.09592343471852349,0.09592343471852349,-0.7795306887569614,-0.1760557512169116,-0.6613290382750641,0.2020690599158886,-0.14840819738674113,0.2020690599158886,-0.5446222359725705,0.06915982780459791,0.2020690599158886,-0.25961361162023794,0.3586803384631244,-0.31582532471033525,0.5629592712307787,0.0423030303136774,-0.011694963440921587,0.5629592712307787,1.5877530843654364,0.30681317218691295,5.8371756458828,0.09592343471852349,-0.4580926446081327,-0.89919637419257,0.2807548615748546,0.25461208410977504,2.8666565464518214,-0.3440813155434071,0.015351842220474437,-0.20380625761557572,-0.690740541170887,-0.4008906448040487,-1.1120471207717453,0.0423030303136774,0.3844911176822035,-0.011694963440921587,-0.06608047527750467,3.515947665912546,-1.3919365530823733,-0.14840819738674113,0.17566672540232964,-0.25961361162023794,-0.14840819738674113,0.3586803384631244,-0.3724366140244755,-0.9293380943113951,-0.06608047527750467,-0.5446222359725705,0.3844911176822035,-0.06608047527750467,-0.23165908496291274,0.6881817808837658,-0.3440813155434071,-0.287669225677637,-0.06608047527750467,-0.4294428411231804,0.5881497579803545,-0.3440813155434071,0.06915982780459791,-0.6613290382750641,1.8114392882780097,0.17566672540232964,-0.7202449724403305,0.17566672540232964,-0.3440813155434071,-0.3440813155434071,0.5376942136598729,0.14917574717760415,-0.6613290382750641,-0.14840819738674113,0.015351842220474437,-0.4008906448040487,-0.011694963440921587,-0.011694963440921587,-0.4580926446081327,0.06915982780459791,-0.8391823888505335,-0.3440813155434071,-0.06608047527750467,-0.1760557512169116,-0.3724366140244755,-0.3724366140244755,-0.20380625761557572,-0.6027867889099643,4.281433897456435,-0.9595690419277156,-0.011694963440921587,-0.0934217780812221,-0.23165908496291274,-0.0934217780812221,-0.20380625761557572,-0.23165908496291274,-0.287669225677637,-0.23165908496291274,0.12259502497299368,-0.573657045269454,0.3586803384631244,4.480069380026726,0.48693710960367753,0.3586803384631244,-0.6027867889099643,-0.03883864144469215,-0.0934217780812221,-0.23165908496291274,-0.4868395050717645,1.005701108892365,-0.0934217780812221,-0.7498418476188665,-0.12086389363611108,-0.690740541170887,-0.690740541170887,0.3844911176822035,-0.4868395050717645,1.4969021778921914,-0.3440813155434071,0.48693710960367753,0.30681317218691295,1.7001960684604143,1.7892843924133246,0.14917574717760415,0.6132664740350646,4.444149955886005,-0.0934217780812221,-0.6613290382750641,1.242719326702117,0.7377704894494206,-0.3440813155434071,0.8848963209599016,0.14917574717760415,-0.3440813155434071,-0.25961361162023794,0.0423030303136774,0.12259502497299368,0.0423030303136774,0.22838382789555492,-0.4294428411231804,-0.5446222359725705,-1.710821845905237,1.242719326702117,-0.25961361162023794,0.6881817808837658,-0.06608047527750467,-0.011694963440921587,-0.9898887809878759,-0.25961361162023794,0.5123537700339801,-0.6613290382750641,0.22838382789555492,0.2020690599158886,0.22838382789555492,-0.5446222359725705,0.09592343471852349,4.281433897456435,0.33278800733023756,-0.03883864144469215,-0.287669225677637,-0.06608047527750467,0.17566672540232964,-0.287669225677637,1.6778049667911492,-0.4868395050717645,-0.03883864144469215,0.14917574717760415,-0.03883864144469215,-0.8691443232390553,-0.4580926446081327,0.3586803384631244,1.3126952984073497,-0.9595690419277156,0.3586803384631244,0.09592343471852349,-0.0934217780812221,0.22838382789555492,-0.8093110242796977,0.4358717352001903,0.5629592712307787,-0.8691443232390553,-0.7498418476188665,0.3586803384631244,-1.4550592541183711,-0.0934217780812221,-0.0934217780812221,-0.6027867889099643,3.2640396895366344,-0.3724366140244755,-0.14840819738674113,2.9471395788264925,-0.25961361162023794,0.14917574717760415,-0.3724366140244755,-0.011694963440921587,-0.1760557512169116,0.2807548615748546,-1.0507929166127075,0.41022127826622157,0.25461208410977504,-5.217254591382774,-0.287669225677637,-0.573657045269454,-0.4580926446081327,-0.3440813155434071,-0.3440813155434071,-0.3440813155434071,0.8116357880463558,-0.14840819738674113,0.957569843538065,-0.3724366140244755,-0.011694963440921587,-0.5446222359725705,0.30681317218691295,0.17566672540232964,-0.06608047527750467,0.4358717352001903,-0.03883864144469215,0.9816668449808295,0.957569843538065,0.4358717352001903,-0.011694963440921587,-0.7498418476188665,0.17566672540232964,-0.31582532471033525
2,453
Sphingolipid metabolism
9
22
2.683866
0.007278
P16278,Q99519,Q13510,P06280,P10619,P04062,P17900,P07686,P06865
Processes and pathways
Reactome Pathways
msigdb_reactome
33,38,71,10,46,78,16,51,27
2222,88,362,1174,1412,78,10,27,51,46,33,16,1013,1556,2212,71,166,38,1456,1465,1466,1774
-0.7498418476188665,1.4511688358424328,0.48693710960367753,-0.03883864144469215,-0.14840819738674113,1.5877530843654364,5.112674566713143,3.74435860301373,2.8666565464518214,2.967179422029158,3.515947665912546,4.480069380026726,0.0423030303136774,-0.20380625761557572,-0.7202449724403305,1.7892843924133246,0.9091852010520033,3.2640396895366344,-0.14840819738674113,-0.14840819738674113,-0.14840819738674113,-0.31582532471033525
2,453
Lysosome
25
40
2.619569
0.008804
P11117,Q99538,P06280,O75503,P17900,P61916,Q14108,P50897,P10253,P06865,P11279,P15586,P11717,P16278,Q15904,Q99519,O14773,P10619,Q99523,P07686,P38571,O15118,P54802,Q13510,P04062
Processes and pathways
KEGG Pathways
msigdb_kegg
4,9,10,12,16,17,18,20,23,27,30,31,32,33,36,38,43,46,49,51,57,58,62,71,78
2239,430,43,58,362,1296,12,78,10,27,51,84,23,46,4,30,32,31,33,16,57,20,62,261,17,1615,2382,71,18,36,332,210,38,49,9,1034,1466,1865,2298,158
-0.7795306887569614,0.41022127826622157,3.0071633344987623,2.5185627027049047,0.48693710960367753,-0.0934217780812221,5.043629738470276,1.5877530843654364,5.112674566713143,3.74435860301373,2.8666565464518214,1.4969021778921914,4.171950719968975,2.967179422029158,5.369004334201069,3.6686452238951888,3.535129278103945,3.6306313072401735,3.515947665912546,4.480069380026726,2.5393209088333624,4.281433897456435,2.223991046325372,0.6383102048089089,4.480069380026726,-0.23165908496291274,-1.3291467261308327,1.7892843924133246,4.444149955886005,3.419625726577343,0.5376942136598729,0.762460586097164,3.2640396895366344,2.9270675607263192,5.249884528644196,0.0423030303136774,-0.14840819738674113,-0.3724366140244755,-0.89919637419257,0.957569843538065
2,453
Hydrolase activity acting on glycosyl bonds
11
24
2.608716
0.009088
P16278,Q99519,P06280,O75503,Q9BTY2,P04062,P17900,P07686,P10253,P06865,P54802
Functions
GO Molecular function
msigdb_gomf
33,38,10,12,14,78,16,51,23,27,62
1740,2419,12,78,10,27,51,84,23,1011,1417,33,16,341,287,765,62,2230,1711,1030,38,14,2365,1820
-0.31582532471033525,-1.77556674425155,5.043629738470276,1.5877530843654364,5.112674566713143,3.74435860301373,2.8666565464518214,1.4969021778921914,4.171950719968975,0.0423030303136774,-0.14840819738674113,3.515947665912546,4.480069380026726,0.5123537700339801,0.5881497579803545,0.17566672540232964,2.223991046325372,-0.7498418476188665,-0.287669225677637,0.0423030303136774,3.2640396895366344,4.658398490383113,-1.1736480958785238,-0.3440813155434071
2,453
Ceramide catabolic process
6
7
2.590696
0.009578
Q99519,Q13510,P06280,P17900,P07686,P06865
Processes and pathways
GO Biological process
msigdb_gobp
38,71,10,16,51,27
78,10,27,51,16,71,38
1.5877530843654364,5.112674566713143,3.74435860301373,2.8666565464518214,4.480069380026726,1.7892843924133246,3.2640396895366344
2,453
Glycosphingolipid metabolic process
6
7
2.590696
0.009578
P16278,Q99519,P06280,P17900,P07686,P06865
Processes and pathways
GO Biological process
msigdb_gobp
33,38,10,16,51,27
78,10,27,51,33,16,38
1.5877530843654364,5.112674566713143,3.74435860301373,2.8666565464518214,3.515947665912546,4.480069380026726,3.2640396895366344
2,453
CD markers
6
11
2.563281
0.010369
P11717,Q92692,Q9Y624,P02786,P11279,P35613
Functions
Protein Atlas Protein class
protein_atlas_protein_class
32,102,50,22,30,96
22,285,2186,134,30,32,96,326,869,102,50
4.24503039697022,0.5881497579803545,-0.690740541170887,1.005701108892365,3.6686452238951888,3.535129278103945,1.3590690210496719,0.5376942136598729,0.12259502497299368,1.2894258439182555,2.886826237557072
2,453
Diseases of glycosylation
6
14
2.553198
0.010674
P16278,O43505,Q99519,P10619,P07686,P06865
Processes and pathways
Reactome Pathways
msigdb_reactome
33,37,38,46,51,27
37,2423,80,27,51,46,33,487,1484,1492,2196,2230,379,38
3.342062664558531,-2.0376854596970393,1.5196912422366828,3.74435860301373,2.8666565464518214,2.967179422029158,3.515947665912546,0.3586803384631244,-0.1760557512169116,-0.1760557512169116,-0.690740541170887,-0.7498418476188665,0.48693710960367753,3.2640396895366344
2,453
Cellular monovalent inorganic cation homeostasis
9
17
2.492833
0.012673
P05026,Q15904,O75503,P55011,Q93050,P50897,Q9Y487,Q96AX1,P51790
Processes and pathways
GO Biological process
msigdb_gobp
190,36,12,149,210,20,158,250,60
12,1299,190,2081,20,457,60,326,149,261,36,210,250,1143,580,1865,158
5.043629738470276,-0.0934217780812221,0.8116357880463558,-0.573657045269454,4.281433897456435,0.3844911176822035,2.414217620077897,0.5376942136598729,0.957569843538065,0.6383102048089089,3.419625726577343,0.762460586097164,0.6632817213848923,-0.011694963440921587,0.30681317218691295,-0.3724366140244755,0.957569843538065
2,453
Exopeptidase activity
8
29
2.487666
0.012858
Q9HB40,P42785,Q92820,Q9UIQ6,O14773,P02786,Q9H3G5,O75976
Functions
GO Molecular function
msigdb_gomf
2,35,39,8,43,22,25,28
43,665,28,22,1010,46,483,961,635,1654,35,1121,1794,1200,1074,1507,2125,1275,39,356,2374,655,25,1955,2,1463,1863,198,8
3.0071633344987623,0.22838382789555492,3.706553969726145,4.24503039697022,0.0423030303136774,2.967179422029158,0.3586803384631244,0.06915982780459791,0.25461208410977504,-0.25961361162023794,3.419625726577343,-0.011694963440921587,-0.3440813155434071,-0.03883864144469215,0.015351842220474437,-0.1760557512169116,-0.6027867889099643,-0.06608047527750467,3.244460903129877,0.5123537700339801,-1.2666927357239461,0.25461208410977504,3.9504686698024036,-0.4294428411231804,5.903022197293731,-0.14840819738674113,-0.3724366140244755,0.8116357880463558,5.284007040232641
2,453
Monovalent inorganic cation homeostasis
9
18
2.46953
0.013529
P05026,Q15904,O75503,P55011,Q93050,P50897,Q9Y487,Q96AX1,P51790
Processes and pathways
GO Biological process
msigdb_gobp
190,36,12,149,210,20,158,250,60
12,1052,1299,190,2081,20,457,60,326,149,261,36,210,250,1143,580,1865,158
5.043629738470276,0.015351842220474437,-0.0934217780812221,0.8116357880463558,-0.573657045269454,4.281433897456435,0.3844911176822035,2.414217620077897,0.5376942136598729,0.957569843538065,0.6383102048089089,3.419625726577343,0.762460586097164,0.6632817213848923,-0.011694963440921587,0.30681317218691295,-0.3724366140244755,0.957569843538065
2,453
Regulation of cellular ph
7
12
2.463511
0.013758
Q15904,O75503,Q93050,P50897,Q9Y487,Q96AX1,P51790
Processes and pathways
GO Biological process
msigdb_gobp
36,12,210,20,158,250,60
12,2081,20,457,60,261,36,210,250,580,1865,158
5.043629738470276,-0.573657045269454,4.281433897456435,0.3844911176822035,2.414217620077897,0.6383102048089089,3.419625726577343,0.762460586097164,0.6632817213848923,0.30681317218691295,-0.3724366140244755,0.957569843538065
2,453
Regulation of ph
7
12
2.463511
0.013758
Q15904,O75503,Q93050,P50897,Q9Y487,Q96AX1,P51790
Processes and pathways
GO Biological process
msigdb_gobp
36,12,210,20,158,250,60
12,2081,20,457,60,261,36,210,250,580,1865,158
5.043629738470276,-0.573657045269454,4.281433897456435,0.3844911176822035,2.414217620077897,0.6383102048089089,3.419625726577343,0.762460586097164,0.6632817213848923,0.30681317218691295,-0.3724366140244755,0.957569843538065
2,453
Receptor
14
30
2.458748
0.013942
P11717,Q92692,Q14739,Q15375,Q99720,Q99523,Q14108,Q9Y624,P02786,Q8WTV0,Q9Y2I1,O15118,P11279,P35613
Functions
Protein Atlas Molecular function
protein_atlas_molecular_function
32,102,42,44,48,49,18,50,22,55,121,58,30,96
621,58,2366,22,285,1053,1989,1055,1832,30,32,1695,131,96,690,18,42,44,297,55,102,1451,49,1453,48,226,121,792,709,50
0.25461208410977504,2.5185627027049047,-1.204577613891265,4.24503039697022,0.5881497579803545,0.015351842220474437,-0.4868395050717645,0.015351842220474437,-0.3724366140244755,3.6686452238951888,3.535129278103945,-0.287669225677637,1.0296732296083115,1.3590690210496719,0.22838382789555492,4.444149955886005,3.0470207808857244,2.987187278496618,0.5881497579803545,2.6631141752887224,1.2894258439182555,-0.14840819738674113,2.9270675607263192,-0.14840819738674113,2.9471395788264925,0.7377704894494206,1.1249518338208409,0.17566672540232964,0.22838382789555492,2.886826237557072
2,453
Abnormal retinal artery morphology
6
19
2.429773
0.015108
P16278,Q99519,P10619,P17900,P07686,P06865
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
33,38,46,16,51,27
2408,319,27,51,46,1238,33,16,1835,962,1752,2118,71,174,1450,38,1466,1289,429
-1.6143034879767137,0.5376942136598729,3.74435860301373,2.8666565464518214,2.967179422029158,-0.06608047527750467,3.515947665912546,4.480069380026726,-0.3724366140244755,0.06915982780459791,-0.31582532471033525,-0.6027867889099643,1.7892843924133246,0.8848963209599016,-0.14840819738674113,3.2640396895366344,-0.14840819738674113,-0.06608047527750467,0.4358717352001903
2,453
Sterol metabolic process
9
29
2.384271
0.017113
P05067,Q14739,P61916,Q15392,Q9UBM7,Q8WTV0,P38571,O15118,Q14849
Processes and pathways
GO Biological process
msigdb_gobp
3,42,17,19,53,55,57,58,59
58,1642,957,78,3,1927,1182,1183,914,57,1486,2261,2029,1968,17,1972,2275,976,1662,42,59,19,395,1382,55,211,53,995,845
2.5185627027049047,-0.25961361162023794,0.06915982780459791,1.5877530843654364,5.8371756458828,-0.4294428411231804,-0.03883864144469215,-0.03883864144469215,0.09592343471852349,2.5393209088333624,-0.1760557512169116,-0.8093110242796977,-0.515682880321347,-0.4580926446081327,4.480069380026726,-0.4580926446081327,-0.8391823888505335,0.06915982780459791,-0.25961361162023794,3.0470207808857244,2.4977678795050133,4.390108836903907,0.46144338568076554,-0.12086389363611108,2.6631141752887224,0.762460586097164,2.8262181251127703,0.06915982780459791,0.14917574717760415
2,453
Vacuolar lumen
24
54
2.372393
0.017673
Q8NHP8,P11117,O00584,Q99538,P06280,Q9BTY2,P17900,P61916,Q14108,Q8IV08,P50897,P10253,P06865,P15586,P16278,Q99519,Q92820,O14773,P10619,P07686,P38571,P54802,Q13510,P04062
Localization
GO Cellular component
msigdb_gocc
0,4,5,9,10,14,16,17,18,21,20,23,27,31,33,38,39,43,46,51,57,62,71,78
5,43,362,957,78,10,27,1744,631,51,1692,84,23,46,4,2022,593,31,33,16,1307,1485,57,862,20,1608,1968,600,62,1612,2401,17,565,1939,1371,374,71,18,1322,21,2004,0,39,333,1088,38,1574,9,14,1090,2279,2050,1466,1777
5.3520399209533815,3.0071633344987623,0.48693710960367753,0.06915982780459791,1.5877530843654364,5.112674566713143,3.74435860301373,-0.31582532471033525,0.25461208410977504,2.8666565464518214,-0.287669225677637,1.4969021778921914,4.171950719968975,2.967179422029158,5.369004334201069,-0.515682880321347,0.2807548615748546,3.6306313072401735,3.515947665912546,4.480069380026726,-0.0934217780812221,-0.1760557512169116,2.5393209088333624,0.12259502497299368,4.281433897456435,-0.23165908496291274,-0.4580926446081327,0.2807548615748546,2.223991046325372,-0.23165908496291274,-1.5185119338049924,4.480069380026726,0.30681317218691295,-0.4294428411231804,-0.12086389363611108,0.48693710960367753,1.7892843924133246,4.444149955886005,-0.0934217780812221,4.281433897456435,-0.4868395050717645,6.357189361817599,3.244460903129877,0.5376942136598729,0.015351842220474437,3.2640396895366344,-0.20380625761557572,5.249884528644196,4.658398490383113,0.015351842220474437,-0.8391823888505335,-0.515682880321347,-0.14840819738674113,-0.31582532471033525
2,453
Abnormality of the liver
24
233
2.364909
0.018035
Q9Y3E5,P61916,Q14108,Q9P032,P10253,P15586,P11717,P16278,Q13546,Q15904,Q99519,Q14739,P10619,P07686,Q9UBM7,P38571,O15118,P54802,Q13510,P04062,O75340,P08236,Q12824,Q5XKP0
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
146,17,18,156,23,31,32,33,160,36,38,42,46,51,53,57,58,62,71,78,80,84,85,108
1401,2239,1737,1353,430,711,58,1741,362,319,625,2423,557,714,520,80,754,1354,902,664,1002,588,953,904,2242,715,482,1743,2256,78,1298,1051,1178,2080,801,1110,909,1179,51,2114,84,959,2140,1542,1543,521,23,46,671,1693,2350,1927,803,32,451,483,1181,364,1883,31,365,33,1184,2189,1650,1421,725,486,2190,1239,1835,1112,2410,1186,2351,2060,858,1424,202,1783,1887,635,1306,1931,435,1889,487,764,962,765,767,1654,1791,1484,963,1115,2191,57,638,2170,1426,1550,1890,1992,1966,1793,1553,2029,2409,1842,2030,1492,2312,1314,970,490,599,1752,2142,62,1612,1708,2194,1613,1431,867,458,1614,17,2118,532,237,533,1996,2405,775,2229,279,2382,1998,85,1437,567,71,160,2230,18,925,1711,42,174,824,1714,1130,36,927,1265,1441,1622,1028,108,229,1506,609,2343,353,1718,695,2068,929,543,1720,932,1080,781,1387,205,1450,505,1627,2317,984,1083,250,1516,2217,2264,270,1518,2399,1980,1810,1336,1337,38,1454,2287,420,1729,2049,839,1149,1150,2161,1526,1815,445,1630,994,2106,1819,789,1466,156,1582,53,1395,1288,1289,407,339,620,1349,748,1228,1821,146,1400,2018,429,751,793,1778
-0.14840819738674113,-0.7795306887569614,-0.31582532471033525,-0.12086389363611108,0.41022127826622157,0.2020690599158886,2.5185627027049047,-0.31582532471033525,0.48693710960367753,0.5376942136598729,0.25461208410977504,-2.0376854596970393,0.30681317218691295,0.2020690599158886,0.33278800733023756,1.5196912422366828,0.17566672540232964,-0.12086389363611108,0.09592343471852349,0.22838382789555492,0.0423030303136774,0.2807548615748546,0.06915982780459791,0.09592343471852349,-0.7795306887569614,0.2020690599158886,0.3586803384631244,-0.31582532471033525,-0.8093110242796977,1.5877530843654364,-0.0934217780812221,0.015351842220474437,-0.03883864144469215,-0.573657045269454,0.14917574717760415,-0.011694963440921587,0.09592343471852349,-0.03883864144469215,2.8666565464518214,-0.6027867889099643,1.4969021778921914,0.06915982780459791,-0.6320109548770719,-0.20380625761557572,-0.20380625761557572,0.33278800733023756,4.171950719968975,2.967179422029158,0.22838382789555492,-0.287669225677637,-1.1120471207717453,-0.4294428411231804,0.14917574717760415,3.535129278103945,0.3844911176822035,0.3586803384631244,-0.03883864144469215,0.48693710960367753,-0.4008906448040487,3.6306313072401735,0.48693710960367753,3.515947665912546,-0.03883864144469215,-0.690740541170887,-0.25961361162023794,-0.14840819738674113,0.2020690599158886,0.3586803384631244,-0.690740541170887,-0.06608047527750467,-0.3724366140244755,-0.011694963440921587,-1.6463959681470162,-0.03883864144469215,-1.1120471207717453,-0.5446222359725705,0.12259502497299368,-0.14840819738674113,0.7870821214860848,-0.3440813155434071,-0.4008906448040487,0.25461208410977504,-0.0934217780812221,-0.4294428411231804,0.41022127826622157,-0.4008906448040487,0.3586803384631244,0.17566672540232964,0.06915982780459791,0.17566672540232964,0.17566672540232964,-0.25961361162023794,-0.3440813155434071,-0.1760557512169116,0.06915982780459791,-0.011694963440921587,-0.690740541170887,2.5393209088333624,0.25461208410977504,-0.6613290382750641,-0.14840819738674113,-0.20380625761557572,-0.4008906448040487,-0.4868395050717645,-0.4580926446081327,-0.3440813155434071,-0.20380625761557572,-0.515682880321347,-1.6143034879767137,-0.3724366140244755,-0.515682880321347,-0.1760557512169116,-0.9595690419277156,-0.0934217780812221,0.06915982780459791,0.3586803384631244,0.2807548615748546,-0.31582532471033525,-0.6320109548770719,2.223991046325372,-0.23165908496291274,-0.287669225677637,-0.690740541170887,-0.23165908496291274,-0.14840819738674113,0.12259502497299368,0.3844911176822035,-0.23165908496291274,4.480069380026726,-0.6027867889099643,0.33278800733023756,0.6881817808837658,0.33278800733023756,-0.4868395050717645,-1.582291761318393,0.17566672540232964,-0.7498418476188665,0.6132664740350646,-1.3291467261308327,-0.4868395050717645,1.4969021778921914,-0.14840819738674113,0.30681317218691295,1.7892843924133246,0.933409500342636,-0.7498418476188665,4.444149955886005,0.09592343471852349,-0.287669225677637,3.0470207808857244,0.8848963209599016,0.14917574717760415,-0.287669225677637,-0.011694963440921587,3.419625726577343,0.09592343471852349,-0.06608047527750467,-0.14840819738674113,-0.23165908496291274,0.0423030303136774,1.242719326702117,0.7130111268205619,-0.1760557512169116,0.2807548615748546,-1.0813764681271592,0.5123537700339801,-0.287669225677637,0.22838382789555492,-0.5446222359725705,0.09592343471852349,0.33278800733023756,-0.287669225677637,0.09592343471852349,0.015351842220474437,0.17566672540232964,-0.12086389363611108,0.7870821214860848,-0.14840819738674113,0.3586803384631244,-0.23165908496291274,-0.9595690419277156,0.06915982780459791,0.015351842220474437,0.6632817213848923,-0.1760557512169116,-0.7202449724403305,-0.8093110242796977,0.6383102048089089,-0.1760557512169116,-1.4550592541183711,-0.4580926446081327,-0.3440813155434071,-0.0934217780812221,-0.0934217780812221,3.2640396895366344,-0.14840819738674113,-0.8691443232390553,0.4358717352001903,-0.287669225677637,-0.515682880321347,0.14917574717760415,-0.011694963440921587,-0.011694963440921587,-0.6320109548770719,-0.1760557512169116,-0.3440813155434071,0.41022127826622157,-0.23165908496291274,0.06915982780459791,-0.573657045269454,-0.3440813155434071,0.17566672540232964,-0.14840819738674113,0.957569843538065,-0.20380625761557572,2.8262181251127703,-0.12086389363611108,-0.06608047527750467,-0.06608047527750467,0.46144338568076554,0.5376942136598729,0.2807548615748546,-0.0934217780812221,0.2020690599158886,-0.03883864144469215,-0.3440813155434071,0.9816668449808295,-0.12086389363611108,-0.4868395050717645,0.4358717352001903,0.2020690599158886,0.17566672540232964,-0.31582532471033525
2,453
Entry into host
11
27
2.33597
0.019493
Q92692,Q9UPT5,Q9BTY2,Q12899,Q14108,Q9Y624,P02786,Q8WTV0,O15118,P11279,P35613
Processes and pathways
GO Biological process
msigdb_gobp
102,109,14,81,18,50,22,55,58,30,96
1871,58,1105,22,285,1053,1415,134,1055,1832,30,1695,806,96,2274,81,18,2353,297,55,102,270,383,14,1224,109,50
-0.4008906448040487,2.5185627027049047,-0.011694963440921587,4.24503039697022,0.5881497579803545,0.015351842220474437,-0.14840819738674113,1.005701108892365,0.015351842220474437,-0.3724366140244755,3.6686452238951888,-0.287669225677637,0.14917574717760415,1.3590690210496719,-0.8391823888505335,1.5196912422366828,4.444149955886005,-1.1120471207717453,0.5881497579803545,2.6631141752887224,1.2894258439182555,0.6383102048089089,0.48693710960367753,4.658398490383113,-0.03883864144469215,1.242719326702117,2.886826237557072
2,453
Abnormality of head blood vessel
8
21
2.319239
0.020382
P16278,Q99519,Q13510,Q15056,P10619,P17900,P07686,P06865
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
33,38,71,174,46,16,51,27
711,2408,319,27,51,46,1238,33,16,1835,962,182,1752,2118,71,174,1450,38,1466,1289,429
0.2020690599158886,-1.6143034879767137,0.5376942136598729,3.74435860301373,2.8666565464518214,2.967179422029158,-0.06608047527750467,3.515947665912546,4.480069380026726,-0.3724366140244755,0.06915982780459791,0.836122266218473,-0.31582532471033525,-0.6027867889099643,1.7892843924133246,0.8848963209599016,-0.14840819738674113,3.2640396895366344,-0.14840819738674113,-0.06608047527750467,0.4358717352001903
2,453
Abnormality of the abdominal organs
20
273
2.295376
0.021712
P61916,Q14108,Q15392,P10253,P15586,P11717,P16278,Q15904,Q99519,Q14739,P10619,P07686,Q9UBM7,P38571,O15118,P54802,Q13510,P04062,O75340,P08236
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
17,18,19,23,31,32,33,36,38,42,46,51,53,57,58,62,71,78,80,84
1401,2239,1737,1353,430,711,58,1741,362,1689,319,625,2423,557,1408,714,520,80,2079,754,1354,902,664,1002,588,953,1478,904,905,2242,715,482,1743,306,1006,307,2256,78,1298,1051,1178,2080,801,1110,909,1179,51,2114,84,959,1055,2140,1542,1543,521,23,46,671,1693,1237,2350,1927,803,32,756,451,483,1181,364,1883,31,365,33,1184,2189,1650,1421,725,486,2190,1239,1835,1112,2410,1186,2351,2060,858,1424,202,1783,1887,635,1306,1931,435,1889,487,764,962,765,767,1654,1791,1484,963,1115,2191,57,638,2170,1426,1550,1890,1992,1966,1793,1553,2029,2409,1842,1554,1607,2030,1492,2312,1314,1016,970,490,599,1969,1752,2142,62,1612,1708,2194,1613,1431,2087,867,458,1614,17,2118,532,237,533,1996,2405,775,2229,279,2382,1998,1201,85,1437,567,71,160,2230,18,925,1711,42,1976,174,824,19,1714,1130,36,927,1265,1441,1622,1028,1208,692,108,229,1506,1855,609,2343,353,1718,695,2068,399,929,543,1720,2151,780,932,379,1138,1080,781,981,1387,884,205,1979,1450,505,1627,2317,984,1083,250,1516,2217,2264,270,383,1518,2235,2399,1980,1810,1336,1337,38,1454,2287,1148,420,1729,2049,839,1149,1150,2161,1526,1815,445,2219,1630,994,2106,1819,789,198,1466,156,1582,53,1395,1288,517,1289,407,339,425,620,1349,1293,748,1228,1821,146,1400,2018,429,1162,1959,751,793,1778
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2,453
Homeostatic process
44
227
2.23898
0.025157
P05067,Q9UIQ6,O75503,P61421,P61916,P08708,P50897,P02786,P10253,Q9Y487,Q13642,Q06481,P55011,Q16763,P42785,Q15904,Q9Y639,Q9NYL9,P13693,O14773,P27695,Q15334,P17612,Q9Y624,P07686,Q5BJF2,Q8WTV0,P38571,O15118,P51790,Q92542,Q15120,P05026,Q13501,P04062,Q93050,Q12824,Q9Y6C9,Q86YV9,Q8IXI2,Q658P3,Q6IAA8,Q96AX1,Q9H9B4
Processes and pathways
GO Biological process
msigdb_gobp
3,8,12,261,17,258,20,22,23,158,280,26,149,298,35,36,169,168,162,43,287,175,286,50,51,52,55,57,58,60,61,194,190,74,78,210,85,86,87,230,229,241,250,123
1233,2239,1737,663,1535,1872,430,2205,43,58,1589,1404,798,1407,1826,2255,2426,12,953,1235,1478,2185,1172,904,2242,1174,589,1540,958,22,78,1298,2349,2281,1007,1052,1299,190,3,630,285,2081,1110,909,51,2114,1879,959,258,1594,1542,1543,1648,1832,23,1927,804,162,364,2025,1695,853,910,1697,723,2391,286,1419,2243,1650,1746,2083,1013,856,2351,1188,287,858,1887,635,1307,1991,342,1839,595,1425,1784,764,57,807,1964,808,2170,1426,1603,35,1116,1993,1793,2404,2029,20,457,2030,1122,60,2031,1969,1065,326,149,1613,682,261,17,492,684,1068,413,530,1255,2413,1021,869,1796,1022,1846,1373,26,1896,2430,85,1257,1562,1756,1497,1204,74,1259,280,2293,2120,1322,570,2121,824,194,1804,175,1264,36,1504,1265,298,1622,396,2034,52,229,241,1029,2321,1509,87,1079,1948,230,1444,2364,1720,471,55,61,210,1083,250,2216,652,1388,2368,2337,1143,2009,1281,1144,476,1861,1089,2452,2132,656,657,1814,2181,1150,1220,123,2250,788,1094,1732,1095,790,2107,168,891,1395,995,580,1865,406,8,2017,2395,1040,2268,1866,1290,1471,1102,585,1350,158,2238,50,169,86
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2,453
Golgi apparatus
42
219
2.225332
0.026059
Q9Y678,P05067,P24390,P06280,Q7Z5K2,O75503,O96013,Q14108,Q15392,Q8IV08,P50897,Q8IY95,Q9BRK5,Q5W0Z9,O95456,P11717,P16278,O43505,P40616,O14773,Q15334,Q99523,O15127,Q9UNK0,Q9UQR1,O15118,P51790,Q92542,P10321,O00461,Q8TB61,Q9BVK6,O43852,P04062,Q93050,P35613,P80303,Q92974,P83436,Q8N4V1,Q02818,P49755
Localization
GO Cellular component
msigdb_gocc
275,3,131,10,143,12,140,18,19,21,20,153,154,151,159,32,33,37,165,43,175,49,178,180,181,58,60,61,63,67,204,206,77,78,210,96,218,100,237,115,125,247
448,2239,1738,622,67,430,2348,947,43,361,1536,1403,58,2390,178,554,556,623,1168,37,1296,1825,77,2272,1001,2207,2137,1171,849,12,2241,1477,1005,1174,159,1050,956,1742,140,307,78,629,1299,3,10,1358,592,63,32,33,673,1418,960,1962,2083,1013,131,391,858,961,1361,1748,1601,323,96,1309,1790,165,726,1116,1792,966,1119,2171,1793,247,2409,862,1843,1607,20,457,1491,1122,60,411,2085,970,1557,1658,491,1432,1196,1559,369,1369,686,415,1070,869,218,237,1615,1895,125,1375,871,328,2382,1998,2033,329,1562,1204,2385,536,1973,18,1379,2386,1711,2304,2276,1852,1323,175,19,875,738,1665,497,741,2095,151,1625,1760,2321,442,352,353,694,143,742,1903,354,2439,1857,21,930,153,115,1328,379,471,204,1950,1673,1215,1448,61,332,380,100,210,1676,507,1143,2399,1628,49,837,1952,154,1813,1147,206,420,1090,302,1034,616,992,1149,272,1150,2050,1684,704,548,1981,405,843,790,1465,1686,1774,619,1775,2289,580,791,2109,1290,2053,180,582,661,2221,181,1161,426,2298,893,2184,1473,1398,2356,275,1823
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2,453
Azurophil granule lumen
10
35
2.208032
0.027242
P16278,O00584,Q92820,P06280,Q9BTY2,P10619,P17900,P61916,P07686,P15586
Localization
GO Cellular component
msigdb_gocc
33,5,39,10,14,46,16,17,51,31
5,362,957,10,1744,631,51,84,46,593,31,33,16,1307,862,1608,1968,600,1612,2401,17,565,1939,1371,374,1322,2004,39,333,1088,1574,14,2279,2050,1777
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2,453
Cell surface interactions at the vascular wall
8
10
2.175739
0.029575
P05026,P08195,Q92896,P05556,Q9Y624,P54709,P14174,P35613
Processes and pathways
Reactome Pathways
msigdb_reactome
190,134,380,285,50,326,364,96
190,285,134,364,96,1969,326,415,380,50
0.8116357880463558,0.5881497579803545,1.005701108892365,0.48693710960367753,1.3590690210496719,-0.4580926446081327,0.5376942136598729,0.4358717352001903,0.48693710960367753,2.886826237557072
2,453
Secondary alcohol metabolic process
10
33
2.155498
0.031123
P05067,Q14739,P04062,P61916,Q15392,Q9UBM7,Q8WTV0,O15118,Q14849,O75874
Processes and pathways
GO Biological process
msigdb_gobp
3,42,78,17,19,53,55,58,59,93
58,950,93,1642,957,78,3,1927,1182,1183,914,1486,2261,113,2029,1489,308,1968,17,1972,2275,976,1662,42,59,19,395,1382,55,1681,211,53,995
2.5185627027049047,0.06915982780459791,1.4052256408261132,-0.25961361162023794,0.06915982780459791,1.5877530843654364,5.8371756458828,-0.4294428411231804,-0.03883864144469215,-0.03883864144469215,0.09592343471852349,-0.1760557512169116,-0.8093110242796977,1.1957860157223068,-0.515682880321347,-0.1760557512169116,0.5629592712307787,-0.4580926446081327,4.480069380026726,-0.4580926446081327,-0.8391823888505335,0.06915982780459791,-0.25961361162023794,3.0470207808857244,2.4977678795050133,4.390108836903907,0.46144338568076554,-0.12086389363611108,2.6631141752887224,-0.25961361162023794,0.762460586097164,2.8262181251127703,0.06915982780459791
2,453
Liposaccharide metabolic process
6
12
2.152296
0.031374
P16278,Q99519,P06280,P17900,P07686,P06865
Processes and pathways
GO Biological process
msigdb_gobp
33,38,10,16,51,27
2402,2423,78,10,27,51,33,16,2443,506,1336,38
-1.5503611285496142,-2.0376854596970393,1.5877530843654364,5.112674566713143,3.74435860301373,2.8666565464518214,3.515947665912546,4.480069380026726,-3.3116206080143495,0.3586803384631244,-0.0934217780812221,3.2640396895366344
2,453
Amino acid transmembrane transport
6
11
2.13569
0.032705
Q15758,P08195,Q15041,P05556,Q9H2J7,Q9H9B4
Processes and pathways
GO Biological process
msigdb_gobp
297,134,173,285,54,123
1537,1538,1411,285,134,173,297,54,123,407,793
-0.20380625761557572,-0.20380625761557572,-0.14840819738674113,0.5881497579803545,1.005701108892365,0.8848963209599016,0.5881497579803545,2.683622503169627,1.101222532398343,0.46144338568076554,0.17566672540232964
2,453
Proteolysis
32
324
2.134191
0.032827
Q9HB40,P05067,Q9UIQ6,Q99538,O75503,Q9NXR7,P42892,A4D1P6,Q15392,P02786,Q9H3G5,Q06481,O43464,O75976,P42785,Q9BUN8,Q92820,O14773,Q15375,P10619,Q15041,P49721,P49427,Q9NZ08,Q8TCJ2,Q92542,Q13501,P04062,O75340,O14967,Q9H2J4,Q92688
Processes and pathways
GO Biological process
msigdb_gobp
2,3,8,9,12,144,15,139,19,22,25,26,147,28,35,167,39,43,44,46,173,184,183,198,197,61,74,78,80,91,99,101
897,139,1637,710,2347,663,1402,43,1588,91,1104,1589,431,480,449,2402,147,2165,798,2432,1923,1875,80,1779,1234,12,628,665,1411,28,1478,1830,363,2185,1642,1356,2056,717,1109,22,78,559,906,1051,3,1053,1781,909,1744,591,2057,1594,1543,1648,1010,1832,46,2082,483,1544,2025,1695,1183,286,673,1649,390,1747,1836,1422,341,1990,455,1187,392,675,858,2026,1701,1424,762,1886,961,635,1991,342,1243,1547,1483,1787,764,1788,1934,1653,1654,1791,1246,2170,2403,35,15,1310,1936,1364,772,1657,1062,291,1993,1793,183,639,184,247,1195,1120,1365,1121,1122,680,863,2211,1892,1248,600,681,2032,1611,1612,1794,1893,459,278,1250,682,920,1560,1894,528,1495,1067,1995,1370,1253,642,868,294,463,1255,1845,1197,2064,869,814,1846,1199,26,464,1998,1200,2383,466,1798,1498,374,1942,1499,1204,74,568,1848,1024,1973,2320,821,1074,537,1128,2353,2314,1850,1851,538,1262,2121,173,2231,825,737,44,2335,19,1713,2437,2001,1504,2147,298,1665,1267,1944,239,1269,978,2095,1507,1443,1945,980,398,1136,1078,742,2125,1274,418,502,1275,2097,2358,696,197,647,2069,2153,2277,61,101,613,39,1450,380,1571,2278,651,1627,1724,1451,356,382,1083,333,403,886,652,2264,270,2368,653,574,1910,2374,1143,1680,2129,1727,1088,1144,9,1217,1218,1768,655,1146,167,2200,1459,512,2279,1862,99,25,1955,1524,358,889,2,318,1463,1981,1580,1527,1095,1956,144,1863,2318,198,1466,1917,2442,255,200,2108,1958,273,1154,406,8,551,2016,274,2017,1468,1632,996,944,425,945,2202,1469,582,1471,585,428,243,2238,478,244,1634,2291,1959,2356,895
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2,453
Ascites
8
24
2.103046
0.035462
Q99519,Q13510,Q14739,P04062,P61916,Q14108,P38571,O15118
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
38,71,42,78,17,18,57,58
58,1170,2429,78,84,671,1883,1184,57,2409,1314,17,344,1198,533,2405,775,71,18,42,1130,1028,38,1630
2.5185627027049047,-0.03883864144469215,-2.2375022942825065,1.5877530843654364,1.4969021778921914,0.22838382789555492,-0.4008906448040487,-0.03883864144469215,2.5393209088333624,-1.6143034879767137,-0.0934217780812221,4.480069380026726,0.5123537700339801,-0.03883864144469215,0.33278800733023756,-1.582291761318393,0.17566672540232964,1.7892843924133246,4.444149955886005,3.0470207808857244,-0.011694963440921587,0.0423030303136774,3.2640396895366344,-0.23165908496291274
2,453
Golgi associated vesicle
8
21
2.08782
0.036814
P11717,Q9Y678,P05067,P24390,Q9BVK6,P35606,Q99523,P49755
Localization
GO Cellular component
msigdb_gocc
32,275,3,131,206,323,49,247
1296,1742,3,32,131,323,966,247,1491,1557,1658,1432,369,1369,1615,1673,49,206,1775,1398,275
-0.0934217780812221,-0.31582532471033525,5.8371756458828,3.535129278103945,1.0296732296083115,0.5376942136598729,0.06915982780459791,0.6632817213848923,-0.1760557512169116,-0.20380625761557572,-0.25961361162023794,-0.14840819738674113,0.48693710960367753,-0.12086389363611108,-0.23165908496291274,-0.25961361162023794,2.9270675607263192,0.7870821214860848,-0.31582532471033525,-0.12086389363611108,0.6383102048089089
2,453
Potential drug targets
30
390
2.08353
0.037203
P11117,O00584,P06280,P42892,P61916,Q14108,Q15392,Q8IV08,P50897,P06865,P15586,P16278,Q15904,Q99519,Q14739,O14773,P10619,Q99523,P07686,Q9UBM7,P38571,O15118,P54802,P35270,Q13510,P04062,Q9Y320,P08236,O15269,O15460
Functions
Protein Atlas Protein class
protein_atlas_protein_class
4,5,10,15,17,18,19,21,20,27,31,33,36,38,42,43,46,49,51,53,57,58,62,69,71,78,83,84,88,92
2204,710,1738,622,2240,663,5,2205,43,711,58,1044,88,1589,340,92,1590,147,276,625,1873,2223,1407,1297,1476,1105,2429,2272,207,1874,2423,2255,714,520,2079,754,1234,902,1877,1002,1828,1538,588,665,1478,1479,1642,1172,189,904,1174,2166,715,1412,2113,2056,482,718,957,306,1108,1109,719,78,1298,559,2281,1176,629,1051,1178,2080,801,10,1110,909,27,2139,1415,591,51,1009,1782,2114,84,959,1300,1054,2168,1542,1543,2187,46,2082,4,1693,1237,1881,2350,1927,803,2400,483,1417,672,408,364,1238,31,365,33,1183,1184,286,594,1419,2189,1650,1421,484,1834,725,1962,1239,1360,1836,1422,2410,632,759,633,1186,2060,454,1652,1304,1241,1598,1929,1424,202,1783,1887,1306,1245,435,1308,1889,913,487,69,765,2209,767,1935,1654,1791,1484,2225,324,914,963,2191,57,1191,638,2403,1193,1426,678,1550,15,437,1312,2261,182,2171,2404,2445,1247,1488,1840,917,2029,1891,1842,1707,1750,1843,2116,20,1751,457,1492,1122,1556,1123,1314,863,1892,490,1248,599,227,1969,601,1315,2142,62,439,1558,1612,1708,2194,1613,1431,2087,867,491,1614,528,1251,17,1070,1021,869,817,1846,1615,2313,1072,818,172,2435,98,2212,2196,279,1376,871,2382,1998,1201,2383,1756,312,71,160,2144,2230,18,925,2314,42,1502,220,1803,824,194,19,395,36,1265,2147,928,1028,221,692,1758,1665,1666,1209,2067,350,2415,878,1384,229,540,1271,571,1029,1135,1945,1805,499,1671,500,1764,1856,742,929,21,543,2150,2151,1276,1446,2344,1858,379,2005,612,1138,1214,197,2041,781,981,648,933,884,505,1627,1083,232,1333,474,699,1516,270,271,1143,2235,508,2399,1810,1680,2129,1144,38,49,2100,252,1218,1681,837,1861,1728,1148,1729,785,656,2102,547,839,357,2071,840,2162,1815,1391,578,659,1733,1527,1630,2378,1983,185,1818,1820,1465,2280,2252,1582,1864,53,1631,2074,1288,1289,407,360,1290,425,2381,661,1291,748,83,146,2018,2238,478,1959,751,1869,946,793
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2,453
Secretory vesicle
30
207
2.068019
0.038638
P05067,O00584,P06280,Q08380,Q9BTY2,P42892,P17900,P61916,P50897,P10253,Q06481,P06865,P11279,P15586,P11717,P16278,P42785,Q99519,Q92820,P10619,P07686,P51790,Q92542,P10321,Q13510,P08236,O75874,P35613,O15439,O60784
Localization
GO Cellular component
msigdb_gocc
3,5,10,11,14,15,16,17,20,23,26,27,30,31,32,33,35,38,39,46,51,60,61,63,71,84,93,96,95,105
1233,1637,1534,621,622,2347,663,5,2390,555,95,449,362,1689,587,2271,1826,1001,105,799,93,1478,1539,956,957,1006,307,1298,559,3,10,1110,909,27,1744,591,631,51,1009,1692,84,2057,592,1594,1543,1010,2021,1832,23,63,46,2082,2022,593,30,32,1303,1833,2367,1882,1111,1544,364,1694,1545,31,2341,33,286,111,16,1649,1418,2243,911,1746,1596,563,390,1187,287,858,1701,1307,1839,595,2061,1933,1788,765,1934,96,1653,2451,1484,861,807,638,678,1427,35,15,1118,2226,247,862,20,1608,1751,368,457,1491,680,60,411,1968,1557,600,1612,491,1432,293,1559,369,2401,261,528,17,1070,294,295,565,1939,345,1371,26,2065,11,1203,1497,1798,1498,374,1204,71,2119,1974,1025,1322,1380,926,1262,1620,264,175,239,2177,241,1210,742,1903,354,932,2004,2443,471,61,39,1571,210,885,507,333,887,2286,2399,1727,475,1088,38,1574,655,1089,1146,14,225,206,1034,1285,2279,839,1149,2050,704,1038,336,1466,1774,845,2109,1159,945,1777,2221,662,158,2019
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2,453
Increased bone mineral density
7
23
2.061515
0.039254
Q15056,Q14739,Q13501,P04062,Q14108,Q15392,P54802
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
174,42,74,78,18,19,62
319,2256,78,1419,484,1962,1241,962,182,62,1612,2118,1895,312,74,18,42,174,19,1027,1289,1293,429
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2,453
Amino acid transport
7
14
2.055965
0.039786
Q15758,P08195,Q15041,P05556,Q9H2J7,Q9H9B4,P55011
Processes and pathways
GO Biological process
msigdb_gobp
297,134,173,285,54,123,149
2205,1537,1538,1411,285,134,149,173,1323,297,54,123,407,793
-0.7202449724403305,-0.20380625761557572,-0.20380625761557572,-0.14840819738674113,0.5881497579803545,1.005701108892365,0.957569843538065,0.8848963209599016,-0.0934217780812221,0.5881497579803545,2.683622503169627,1.101222532398343,0.46144338568076554,0.17566672540232964
2,453
Molecular transducer activity
8
23
2.038998
0.04145
P11717,Q92692,Q15375,Q99720,Q99523,Q14108,Q8WTV0,O15118
Functions
GO Molecular function
msigdb_gomf
32,102,44,48,49,18,55,58
58,2366,2135,285,32,2170,1793,534,690,18,44,826,297,2354,55,102,1451,49,48,167,1581,1288,1866
2.5185627027049047,-1.204577613891265,-0.6320109548770719,0.5881497579803545,3.535129278103945,-0.6613290382750641,-0.3440813155434071,0.33278800733023756,0.22838382789555492,4.444149955886005,2.987187278496618,0.14917574717760415,0.5881497579803545,-1.1120471207717453,2.6631141752887224,1.2894258439182555,-0.14840819738674113,2.9270675607263192,2.9471395788264925,0.9091852010520033,-0.20380625761557572,-0.06608047527750467,-0.3724366140244755
2,453
Diseases of metabolism
11
33
2.034947
0.041856
P16278,O43505,Q99519,P10619,O75340,P07686,P08236,P10253,P06865,P54802,P15586
Processes and pathways
Reactome Pathways
msigdb_reactome
33,37,38,46,80,51,84,23,27,62,31
37,2423,80,93,1178,2080,27,51,84,23,46,803,408,31,33,1186,487,1484,963,2273,2116,1492,62,2196,1756,2230,1856,379,1516,1810,38,1860,1391
3.342062664558531,-2.0376854596970393,1.5196912422366828,1.4052256408261132,-0.03883864144469215,-0.573657045269454,3.74435860301373,2.8666565464518214,1.4969021778921914,4.171950719968975,2.967179422029158,0.14917574717760415,0.4358717352001903,3.6306313072401735,3.515947665912546,-0.03883864144469215,0.3586803384631244,-0.1760557512169116,0.06915982780459791,-0.8391823888505335,-0.6027867889099643,-0.1760557512169116,2.223991046325372,-0.690740541170887,-0.31582532471033525,-0.7498418476188665,-0.3724366140244755,0.48693710960367753,-0.1760557512169116,-0.3440813155434071,3.2640396895366344,-0.3724366140244755,-0.12086389363611108
2,453
Locomotory behavior
8
26
2.034674
0.041884
P05067,P07686,P50897,P10253,O43464,O15118,P51790,P54802
Processes and pathways
GO Biological process
msigdb_gobp
3,51,20,23,147,58,60,62
897,58,147,665,755,559,2281,3,51,1541,23,726,1117,966,20,2312,60,62,1499,175,2321,1276,508,2399,1144,1915
0.09592343471852349,2.5185627027049047,0.957569843538065,0.22838382789555492,0.17566672540232964,0.30681317218691295,-0.8691443232390553,5.8371756458828,2.8666565464518214,-0.20380625761557572,4.171950719968975,0.2020690599158886,-0.011694963440921587,0.06915982780459791,4.281433897456435,-0.9595690419277156,2.414217620077897,2.223991046325372,-0.1760557512169116,0.8848963209599016,-0.9898887809878759,-0.06608047527750467,0.3586803384631244,-1.4550592541183711,-0.011694963440921587,-0.4008906448040487
2,453
Multi multicellular organism process
7
20
2.011397
0.044284
Q9UIQ6,P47914,Q96EP5,P07686,Q9BQE5,Q07021,P35613
Processes and pathways
GO Biological process
msigdb_gobp
8,260,116,51,211,279,96
1476,51,1237,673,858,342,96,1060,260,1372,279,1437,1273,2199,116,211,512,477,8,1159
-0.1760557512169116,2.8666565464518214,-0.06608047527750467,0.22838382789555492,0.12259502497299368,0.5123537700339801,1.3590690210496719,0.015351842220474437,0.6383102048089089,-0.12086389363611108,0.6132664740350646,-0.14840819738674113,-0.06608047527750467,-0.690740541170887,1.1722330401086165,0.762460586097164,0.3586803384631244,0.3844911176822035,5.284007040232641,-0.011694963440921587
2,453
Alcohol biosynthetic process
6
25
1.99357
0.046199
P35270,Q13510,Q14739,P04062,Q15392,Q9UBM7
Processes and pathways
GO Biological process
msigdb_gobp
69,71,42,78,19,53
186,88,1642,1743,957,78,1927,1182,1183,723,69,914,1486,2261,1968,2275,71,976,42,19,395,1382,1144,1816,53
0.8116357880463558,1.4511688358424328,-0.25961361162023794,-0.31582532471033525,0.06915982780459791,1.5877530843654364,-0.4294428411231804,-0.03883864144469215,-0.03883864144469215,0.2020690599158886,1.8114392882780097,0.09592343471852349,-0.1760557512169116,-0.8093110242796977,-0.4580926446081327,-0.8391823888505335,1.7892843924133246,0.06915982780459791,3.0470207808857244,4.390108836903907,0.46144338568076554,-0.12086389363611108,-0.011694963440921587,-0.3440813155434071,2.8262181251127703
2,453
Cognition
6
29
1.973673
0.048419
Q9Y639,P05067,Q99538,P17900,P50897,Q92542
Processes and pathways
GO Biological process
msigdb_gobp
169,3,9,16,20,61
897,621,1411,3,285,909,16,960,1191,1192,1116,1117,20,2312,2401,1846,1204,175,2096,1210,1721,61,936,9,1145,839,1814,1733,169
0.09592343471852349,0.25461208410977504,-0.14840819738674113,5.8371756458828,0.5881497579803545,0.09592343471852349,4.480069380026726,0.06915982780459791,-0.03883864144469215,-0.03883864144469215,-0.011694963440921587,-0.011694963440921587,4.281433897456435,-0.9595690419277156,-1.5185119338049924,-0.3724366140244755,-0.03883864144469215,0.8848963209599016,-0.573657045269454,-0.03883864144469215,-0.287669225677637,2.2665381217327427,0.09592343471852349,5.249884528644196,-0.011694963440921587,0.14917574717760415,-0.3440813155434071,-0.287669225677637,0.9091852010520033
2,453
Ficolin 1 rich granule membrane
6
16
1.96364
0.049572
P42785,Q5T4S7,Q6IAA8,Q93050,P10253,P11279
Localization
GO Cellular component
msigdb_gocc
35,239,241,210,23,30
1826,1539,23,30,2341,1788,35,1557,528,1070,294,239,2177,241,210,2019
-0.3724366140244755,-0.20380625761557572,4.171950719968975,3.6686452238951888,-1.0813764681271592,-0.3440813155434071,3.419625726577343,-0.20380625761557572,0.33278800733023756,0.015351842220474437,0.5881497579803545,0.6881817808837658,-0.6613290382750641,0.6881817808837658,0.762460586097164,-0.4868395050717645
2,453
Anion transmembrane transport
21
32
3.68454
0.000229
Q15041,P21796,P45880,Q9HC21,P12236,Q02978,Q9H2D1,Q9UJS0,O75915,O43808,P55011,P12235,Q9UHG3,Q8TB61,Q9UBX3,P08183,O60831,P41440,Q9Y619,P53985,Q9Y277
Processes and pathways
GO Biological process
msigdb_gobp
257,4,9,395,268,269,19,190,430,199,453,328,81,89,98,102,356,113,247,243,254
934,199,356,449,430,579,1463,102,701,328,268,4,113,9,564,243,453,1164,269,1342,257,1001,89,19,537,395,98,81,190,254,752,247
0.012261766202505511,1.1888087414829134,0.6965666233732747,0.5001743392837531,0.52234553017664,0.3194792443862884,-0.2881148841460918,1.943231687090569,0.20339915436107567,0.7605096364061595,0.9275265680799114,4.74928169955365,1.803399105103299,4.32018840610342,0.34239806515772686,1.0294476924989449,0.5001743392837531,-0.11080430109146022,0.9275265680799114,-0.21138289682271152,0.9685159401768403,-0.012122264895228883,2.1969918252112093,3.615273061933848,0.38794646809693123,0.6101447149693627,2.0119466690005705,2.360488763981409,1.2279642966195432,0.988899533020003,0.1798787174258492,1.0294476924989449
2,454