term
stringlengths
2
121
overlap
int64
6
281
setsize
int64
7
499
score
float64
1.96
10.6
pval
float64
0
0.05
edge
stringlengths
41
1.97k
type
stringclasses
5 values
subtype
stringclasses
24 values
subtype_key
stringclasses
24 values
edge_idxs
stringlengths
11
1.17k
ann_idxs
stringlengths
19
2.31k
ann_vals
stringlengths
124
9.94k
sig_size
int64
2.2k
3.73k
Transport of small molecules
45
130
2.786712
0.005325
P23634,Q658P3,P51790,P28072,Q9Y487,P21796,Q9H2J7,P09601,P16615,P28288,P45880,P30519,Q70HW3,Q9UL46,O95202,P05141,Q8N4V1,Q9C0H2,Q93050,Q9Y277,P12235,Q13616,Q8WTV0,O00400,Q9UBX3,P12236,Q8TB61,Q96TA2,P61916,Q9UBV2,Q9HD20,P55011,Q99797,Q9BUN8,P53985,P08183,P05023,Q10713,Q15904,P20618,O15118,P35613,P20020,P49721,Q99623
Processes and pathways
Reactome Pathways
msigdb_reactome
388,135,395,270,13,14,143,17,146,277,22,23,153,418,157,285,33,35,36,170,299,301,46,173,48,175,57,318,317,202,78,337,211,84,214,90,217,223,226,357,102,107,247,252,382
612,2328,173,2177,1709,102,924,575,411,1741,1614,2362,654,2136,157,1579,884,217,563,285,1334,504,90,607,17,1101,299,175,1492,146,886,1102,247,1022,357,2295,2325,1056,14,388,1996,1580,1619,1863,1947,1023,270,630,277,23,860,473,673,107,2266,598,1685,2416,2023,1896,22,1516,2246,252,1025,395,214,488,337,1518,1817,1190,531,614,317,1130,1434,1691,1589,1318,2001,1901,815,223,678,1169,1405,1134,2168,301,2051,1194,664,226,135,627,153,2204,1246,33,1475,57,46,1604,36,918,920,318,724,1562,382,211,725,84,35,2258,143,78,202,48,747,952,1385,592,418,1510,995,170,13,1045
0.33196227773033055,-1.1315983345381757,1.6292815636710885,-0.851816319929439,-0.4675326981198081,2.1608111690827836,0.04337709946176049,0.3966486055076561,0.6741288888174748,-0.48787858846125165,-0.4071533609458661,-1.254512242689449,0.2660959890242387,-0.8071277827585696,1.707357730711625,-0.3872427236161005,0.07854103289676595,1.3103129401771128,0.41264038385623686,1.026794211311183,-0.23169227715850227,0.4915496270065848,2.2838588768570314,0.34824294069161715,3.312159535019784,-0.1007594861270674,0.9862888463465534,1.6179808316611837,-0.32814340269650955,1.805183895274069,0.07854103289676595,-0.1007594861270674,1.1714327633031296,-0.04604169644634782,0.8051750649785682,-1.0360339359435122,-1.1074820632844848,-0.06419045128865337,3.4383036215791014,0.7329693277559037,-0.6761532333776855,-0.3872427236161005,-0.4071533609458661,-0.5703894458091343,-0.63348914849447,-0.04604169644634782,1.08008416772596,0.2991791157749035,1.053540441532829,3.236770177586504,0.09599672590438624,0.5534510197557548,0.2494403407682528,2.1511554521015115,-0.9891352838762909,0.36445047971555095,-0.44729726533392017,-1.6764363701881217,-0.6976683628564239,-0.5913048144722944,3.2506107876916754,-0.34773878122711316,-0.9428079094452866,1.1585282871204687,-0.04604169644634782,0.7183502411380084,1.3349780380688931,0.522633995537609,0.8618984355820165,-0.34773878122711316,-0.5289062519642656,-0.15630455409864116,0.4601935811647347,0.33196227773033055,0.9177256601343565,-0.11918144832285707,-0.2892607576646261,-0.44729726533392017,-0.3872427236161005,-0.2127003983705159,-0.6761532333776855,-0.5913048144722944,0.13065927350069947,1.2979142914342985,0.2494403407682528,-0.13769618095212716,-0.26997150484729665,-0.11918144832285707,-0.8294060110663698,0.9862888463465534,-0.7193072862402492,-0.15630455409864116,0.2660959890242387,1.2854711855638465,1.889836756325383,0.31560787666756207,1.7293410708596129,-0.8743601688607926,-0.17500744981820085,3.0290421086807306,-0.3086510615816659,2.610978516529192,2.7751176885302846,-0.3872427236161005,2.9768207877432644,0.06100140790540697,0.06100140790540697,0.9177256601343565,0.2158976081565213,-0.3674382117784822,0.7475285012988273,1.3472450660860968,0.2158976081565213,2.3664570959280136,2.9843329816197044,-0.9659009950668074,1.8477745387244804,2.4470470431650044,1.4199477449748363,2.726736385136414,0.19900919256781674,0.02566734622848883,-0.2507823308904216,0.3805855015225713,0.6741288888174748,-0.32814340269650955,-0.010011590331103102,1.6629614855267152,3.45129403999315,-0.04604169644634782
2,454
Mitochondrial protein import
19
32
2.77858
0.00546
O60830,Q9NS69,Q99595,P21796,Q9Y512,O96008,Q5JRX3,O14925,P12235,O75746,Q9NX63,Q8N4H5,P12236,Q15388,Q9Y5J9,Q10713,Q13505,O43615,Q9UJS0
Processes and pathways
Reactome Pathways
msigdb_reactome
0,1,2,14,284,412,167,165,299,423,303,47,175,308,323,223,97,355,250
165,355,0,2292,422,1741,423,1308,412,529,576,2120,299,175,14,1104,2212,578,223,97,308,512,167,47,2,1936,1299,1,303,250,284,323
1.6741147827555374,0.8051750649785682,4.5070088122225345,-1.0360339359435122,0.6592655098222254,-0.48787858846125165,0.6592655098222254,-0.2127003983705159,0.6741288888174748,0.4601935811647347,0.3966486055076561,-0.7849801986775056,0.9862888463465534,1.6179808316611837,3.4383036215791014,-0.1007594861270674,-0.8970390410527324,0.3966486055076561,1.2979142914342985,2.1991575594968427,0.9726826435647435,0.4915496270065848,1.6741147827555374,2.751016824478013,4.326911646644879,-0.6123376390093992,-0.19380576235625954,4.336663022143436,0.9862888463465534,1.1714327633031296,1.0401928182614306,0.9038514320983293
2,454
Mitochondrial respiratory chain complex assembly
14
28
2.777896
0.005471
O75880,Q9H061,O95831,O75306,Q86Y39,Q8IUX1,Q9Y2R0,Q9BSK2,Q9Y375,O43676,Q9Y512,Q9NX14,Q69YU5,Q6DKK2
Processes and pathways
GO Biological process
msigdb_gobp
387,4,160,356,249,140,18,51,343,27,284,384,30,255
27,693,356,1769,387,503,1360,160,2159,602,1137,845,30,255,1437,249,140,647,1208,51,4,1040,384,468,18,343,284,419
3.123830761702728,0.23270776762766546,0.8051750649785682,-0.508336059704949,0.7329693277559037,0.4915496270065848,-0.2507823308904216,1.6852317773417498,-0.8294060110663698,0.36445047971555095,-0.11918144832285707,0.1133692286956227,3.102203569906441,1.1455759264064622,-0.2892607576646261,1.1714327633031296,1.8688709393675171,0.28267536563664253,-0.15630455409864116,2.702273873382328,3.7831470025227314,-0.04604169644634782,0.7475285012988273,0.5687606043241162,3.312159535019784,0.8478026431297777,1.0401928182614306,0.6741288888174748
2,454
Protein transmembrane transport
11
21
2.76412
0.005708
O60830,Q9NS69,Q99595,O95831,O43615,O14925,Q15388,P31751,O75381,Q15629,P49755
Processes and pathways
GO Biological process
msigdb_gobp
0,1,2,160,355,165,308,402,335,29,346
165,355,0,335,1308,160,412,2120,402,346,1627,1663,601,816,308,29,512,2,1299,1,498
1.6741147827555374,0.8051750649785682,4.5070088122225345,0.8618984355820165,-0.2127003983705159,1.6852317773417498,0.6741288888174748,-0.7849801986775056,0.6889304882517738,0.8336504314439626,-0.4071533609458661,-0.42717118320069314,0.36445047971555095,0.13065927350069947,0.9726826435647435,3.102203569906441,0.4915496270065848,4.326911646644879,-0.19380576235625954,4.336663022143436,0.5071254977386024
2,454
Sterol metabolic process
16
29
2.763689
0.005715
P61916,P48449,Q9BQE5,Q14849,O15118,P05067,P04062,P16435,P37268,P14324,Q9UBM7,Q8WTV0,Q14739,Q15392,Q16850,Q14534
Processes and pathways
GO Biological process
msigdb_gobp
317,291,3,5,102,199,71,103,10,171,201,46,52,374,61,190
102,654,670,71,199,1310,171,103,10,2416,1106,291,1082,1969,317,2001,2406,2002,190,52,5,374,745,61,46,3,201,392,952
2.1608111690827836,0.2660959890242387,0.2494403407682528,2.4909843512906855,1.4199477449748363,-0.2127003983705159,1.6405450993859982,2.1608111690827836,3.48994747351802,-1.6764363701881217,-0.1007594861270674,1.013344258369898,-0.08242943604018182,-0.6547605908794988,0.9177256601343565,-0.6761532333776855,-1.5395856690495455,-0.6761532333776855,1.4911509912268668,2.685863124657544,3.7597378659854743,0.7620282155096825,0.19900919256781674,2.585631778102509,2.7751176885302846,4.125008978537356,1.4199477449748363,0.7329693277559037,0.02566734622848883
2,454
Secondary active transmembrane transporter activity
10
15
2.755877
0.005854
P05141,P12235,O00400,Q9H2J7,P55011,P12236,Q9UBX3,P53985,Q02978,O95202
Functions
GO Molecular function
msigdb_gomf
285,299,173,143,337,175,48,214,281,157
173,157,285,607,299,175,508,395,214,337,616,281,664,143,48
1.6292815636710885,1.707357730711625,1.026794211311183,0.34824294069161715,0.9862888463465534,1.6179808316611837,0.4915496270065848,0.7183502411380084,1.3349780380688931,0.8618984355820165,0.33196227773033055,1.0401928182614306,0.2660959890242387,1.8477745387244804,2.726736385136414
2,454
Primary mitochondrial disease
27
70
2.755614
0.005858
O75880,P00403,Q8IUX1,Q7L0Y3,Q9Y2R0,Q9H0R6,Q70HW3,O43676,Q9Y6M9,Q53H12,O95831,P22695,P12235,Q9UBX3,O14949,Q9NPL8,P20674,Q96IX5,Q99797,Q9Y375,O75306,Q5XKP0,P13073,O60313,Q86Y39,Q9NX14,Q6DKK2
Drugs and Diseases
Protein Atlas Disease involvement
protein_atlas_disease_involvement
387,263,140,399,18,415,153,27,419,426,160,294,299,48,55,188,440,328,211,343,356,240,115,245,249,384,255
500,55,27,245,693,356,1769,1615,387,1360,160,263,885,576,2275,299,115,1776,440,294,1104,2159,1458,1967,1623,1233,2162,1548,1026,1191,987,602,742,845,1786,426,626,2202,240,255,153,399,249,140,647,584,1702,2224,328,992,211,2037,1208,803,415,1040,2152,188,384,468,1645,48,18,857,1072,343,1832,1177,2262,419
0.4915496270065848,2.652792387509817,3.123830761702728,1.184289682202268,0.23270776762766546,0.8051750649785682,-0.508336059704949,-0.4071533609458661,0.7329693277559037,-0.2507823308904216,1.6852317773417498,1.0932809768597807,0.07854103289676595,0.3966486055076561,-1.0125123853599192,0.9862888463465534,2.0230322589366674,-0.508336059704949,0.6293514881429343,0.9998425933519748,-0.1007594861270674,-0.8294060110663698,-0.3086510615816659,-0.6547605908794988,-0.4071533609458661,-0.17500744981820085,-0.8294060110663698,-0.3674382117784822,-0.04604169644634782,-0.15630455409864116,-0.010011590331103102,0.36445047971555095,0.19900919256781674,0.1133692286956227,-0.508336059704949,0.6592655098222254,0.31560787666756207,-0.8743601688607926,1.2225783190817734,1.1455759264064622,1.7293410708596129,0.7036707826264457,1.1714327633031296,1.8688709393675171,0.28267536563664253,0.3966486055076561,-0.44729726533392017,-0.8970390410527324,0.8899224210436362,-0.010011590331103102,1.3472450660860968,-0.6976683628564239,-0.15630455409864116,0.14786758317336363,0.6741288888174748,-0.04604169644634782,-0.8071277827585696,1.5145620294556341,0.7475285012988273,0.5687606043241162,-0.4071533609458661,2.726736385136414,3.312159535019784,0.1133692286956227,-0.06419045128865337,0.8478026431297777,-0.5289062519642656,-0.13769618095212716,-0.9659009950668074,0.6741288888174748
2,454
Cellular monovalent inorganic cation homeostasis
11
17
2.751952
0.005924
P50897,Q15904,Q93050,O75503,P54709,P51790,Q9Y487,P55011,P06576,Q96AX1,P05023
Processes and pathways
GO Biological process
msigdb_gobp
32,226,36,122,488,395,13,337,529,547,217
122,217,563,529,32,738,395,488,337,614,226,36,547,920,1421,1385,13
1.9622100740129906,1.3103129401771128,0.41264038385623686,0.4601935811647347,3.0364336472060622,0.19900919256781674,0.7183502411380084,0.522633995537609,0.8618984355820165,0.33196227773033055,1.2854711855638465,2.9768207877432644,0.4444122970173833,0.06100140790540697,-0.26997150484729665,-0.2507823308904216,3.45129403999315
2,454
Monovalent inorganic cation homeostasis
11
18
2.738861
0.006165
P50897,Q15904,Q93050,O75503,P54709,P51790,Q9Y487,P55011,P06576,Q96AX1,P05023
Processes and pathways
GO Biological process
msigdb_gobp
32,226,36,122,488,395,13,337,529,547,217
122,906,217,563,529,32,738,395,488,337,614,226,36,547,920,1421,1385,13
1.9622100740129906,0.06100140790540697,1.3103129401771128,0.41264038385623686,0.4601935811647347,3.0364336472060622,0.19900919256781674,0.7183502411380084,0.522633995537609,0.8618984355820165,0.33196227773033055,1.2854711855638465,2.9768207877432644,0.4444122970173833,0.06100140790540697,-0.26997150484729665,-0.2507823308904216,3.45129403999315
2,454
Organelle membrane contact site
9
13
2.738791
0.006167
O96008,Q96N66,Q14849,Q9NTJ5,Q5XKP0,Q9Y320,Q15388,P51572,P27824
Localization
GO Cellular component
msigdb_gocc
412,130,5,267,240,334,308,180,314
420,905,1426,412,314,180,5,308,240,130,853,267,334
0.6592655098222254,0.06100140790540697,-0.2892607576646261,0.6741288888174748,0.9315455033685286,1.572401341063591,3.7597378659854743,0.9726826435647435,1.2225783190817734,1.9313825785356158,0.1133692286956227,1.0932809768597807,0.8759382244797788
2,454
Protein insertion into er membrane
6
13
2.715657
0.006614
P49069,Q8N4V1,P46379,O43681,Q96A33,Q15629
Processes and pathways
GO Biological process
msigdb_gobp
127,33,81,151,155,29
151,1836,81,127,601,643,29,568,1287,33,683,155,225
1.7836865416843557,-0.5495903224499785,2.393539051580102,1.9416897191826263,0.36445047971555095,0.28267536563664253,3.102203569906441,0.41264038385623686,-0.19380576235625954,3.0290421086807306,0.2494403407682528,1.7293410708596129,1.2979142914342985
2,454
Nucleotide transmembrane transport
6
9
2.712975
0.006668
P05141,Q9H2D1,O43808,P12236,Q9BSK2,Q8TB61
Processes and pathways
GO Biological process
msigdb_gobp
285,6,168,175,51,57
924,168,285,299,175,508,57,51,6
0.04337709946176049,1.6629614855267152,1.026794211311183,0.9862888463465534,1.6179808316611837,0.4915496270065848,2.610978516529192,2.702273873382328,3.6277474447573046
2,454
Steroid biosynthetic process
12
33
2.708021
0.006769
Q14849,P16435,P37268,P14324,Q9UBM7,Q13510,Q53GQ0,P05023,Q14739,P28288,Q16850,Q14534
Processes and pathways
GO Biological process
msigdb_gobp
5,103,10,171,201,45,145,217,52,277,61,190
654,670,217,1310,171,1743,103,1103,1057,277,10,1106,291,1969,2406,45,2002,190,52,5,374,1409,745,61,145,1378,2013,873,1248,1643,201,980,952
0.2660959890242387,0.2494403407682528,1.3103129401771128,-0.2127003983705159,1.6405450993859982,-0.48787858846125165,2.1608111690827836,-0.1007594861270674,-0.06419045128865337,1.053540441532829,3.48994747351802,-0.1007594861270674,1.013344258369898,-0.6547605908794988,-1.5395856690495455,2.8227904319852435,-0.6761532333776855,1.4911509912268668,2.685863124657544,3.7597378659854743,0.7620282155096825,-0.26997150484729665,0.19900919256781674,2.585631778102509,1.8371768966766115,-0.2507823308904216,-0.6761532333776855,0.09599672590438624,-0.17500744981820085,-0.4071533609458661,1.4199477449748363,0.00787137682826172,0.02566734622848883
2,454
Cardiac muscle contraction
7
17
2.693133
0.007078
P00403,P16615,Q9UDW1,P13073,O14949,P14406,P05023
Processes and pathways
KEGG Pathways
msigdb_kegg
263,146,19,115,55,26,217
55,263,217,563,1919,576,1616,766,115,26,732,146,440,294,656,488,19
2.652792387509817,1.0932809768597807,1.3103129401771128,0.41264038385623686,-0.6123376390093992,0.3966486055076561,-0.4071533609458661,0.16499487134818433,2.0230322589366674,3.1310075169748237,0.19900919256781674,1.805183895274069,0.6293514881429343,0.9998425933519748,0.2660959890242387,0.522633995537609,3.3053793135556817
2,454
Inorganic ion transmembrane transport
42
88
2.673037
0.007517
O00483,P23634,P00403,P51790,P21796,Q9H2J7,P16615,Q9UDW1,P06576,Q9UM00,Q02978,O95202,P05141,Q8N4V1,O75027,O75964,P12235,O00400,O75947,Q9UBX3,P05026,P20674,Q13423,P08574,P78417,Q9HD20,Q9UJZ1,P24539,P55011,P61619,P56385,P05023,P08195,Q00325,P54709,P61421,Q9UHG3,Q6P4Q7,P56134,P13073,P20020,Q99623
Processes and pathways
GO Biological process
msigdb_gobp
500,388,263,395,14,143,146,19,529,279,281,157,285,33,411,40,299,173,551,48,563,440,72,576,580,78,592,80,337,601,475,217,607,616,488,614,112,366,363,115,247,382
173,500,2263,1051,2116,411,693,1741,551,40,157,263,217,563,285,671,529,1811,1684,607,576,766,1310,299,115,146,886,247,440,2295,2325,2401,14,388,80,1104,1621,1339,860,656,754,1685,2023,2198,1340,2181,718,395,488,337,363,475,614,601,1463,580,616,1670,281,1435,1240,2167,1275,72,2168,892,366,1324,1246,33,723,628,920,2269,382,725,1208,2258,143,78,48,19,1421,112,1385,592,279,1045
1.6292815636710885,0.4915496270065848,-0.9891352838762909,-0.06419045128865337,-0.7849801986775056,0.6741288888174748,0.23270776762766546,-0.48787858846125165,0.42856142165780864,2.938995264788679,1.707357730711625,1.0932809768597807,1.3103129401771128,0.41264038385623686,1.026794211311183,0.2494403407682528,0.4601935811647347,-0.5289062519642656,-0.44729726533392017,0.34824294069161715,0.3966486055076561,0.16499487134818433,-0.2127003983705159,0.9862888463465534,2.0230322589366674,1.805183895274069,0.07854103289676595,1.1714327633031296,0.6293514881429343,-1.0360339359435122,-1.1074820632844848,-1.5127841056693392,3.4383036215791014,0.7329693277559037,2.4025173766417525,-0.1007594861270674,-0.4071533609458661,-0.23169227715850227,0.09599672590438624,0.2660959890242387,0.18204184259460307,-0.44729726533392017,-0.6976683628564239,-0.8743601688607926,-0.23169227715850227,-0.851816319929439,0.2158976081565213,0.7183502411380084,0.522633995537609,0.8618984355820165,0.7764689191291888,0.5534510197557548,0.33196227773033055,0.36445047971555095,-0.3086510615816659,0.3966486055076561,0.33196227773033055,-0.42717118320069314,1.0401928182614306,-0.2892607576646261,-0.17500744981820085,-0.8294060110663698,-0.19380576235625954,2.4909843512906855,-0.8294060110663698,0.07854103289676595,0.7764689191291888,-0.2127003983705159,-0.17500744981820085,3.0290421086807306,0.2158976081565213,0.31560787666756207,0.06100140790540697,-0.9891352838762909,0.7475285012988273,0.2158976081565213,-0.15630455409864116,-0.9659009950668074,1.8477745387244804,2.4470470431650044,2.726736385136414,3.3053793135556817,-0.26997150484729665,2.0728909396765256,-0.2507823308904216,0.3805855015225713,1.053540441532829,-0.04604169644634782
2,454
Metalloendopeptidase activity
8
15
2.667326
0.007646
O43847,Q5JRX3,P22695,O75844,P42892,Q99797,Q96TA2,Q10713
Functions
GO Molecular function
msigdb_gomf
132,167,294,106,77,211,318,223
132,1741,106,1230,294,77,1750,760,223,167,353,318,211,560,1045
1.910673480620233,-0.48787858846125165,2.1511554521015115,-0.17500744981820085,0.9998425933519748,2.4470470431650044,-0.48787858846125165,0.18204184259460307,1.2979142914342985,1.6741147827555374,0.8194413803231336,0.9177256601343565,1.3472450660860968,0.42856142165780864,-0.04604169644634782
2,454
Membrane lipid biosynthetic process
7
16
2.66648
0.007665
P04062,Q8NBX0,Q13510,Q96G23,O95470,Q06136,Q9P035
Processes and pathways
GO Biological process
msigdb_gobp
71,75,45,21,116,24,187
316,203,1487,116,71,1103,24,45,426,75,2359,21,1724,2244,187,1301
0.9177256601343565,1.3958829972159683,-0.32814340269650955,2.0129711959011636,2.4909843512906855,-0.1007594861270674,3.194884274897394,2.8227904319852435,0.6592655098222254,2.4558814235873045,-1.229612257291912,3.264391530678441,-0.4675326981198081,-0.9198544438847963,1.5262080593683736,-0.19380576235625954
2,454
Ion transport
21
40
2.65852
0.007848
P23634,Q658P3,P51790,Q9Y487,P21796,Q9H2J7,P16615,P45880,Q9UM00,O95202,Q9C0H2,Q93050,O75964,Q9Y277,P24539,P55011,P05023,Q15904,Q6P4Q7,P56134,P20020
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
388,135,395,13,14,143,146,22,279,157,35,36,40,170,80,337,217,226,366,363,247
2329,551,40,157,412,217,563,529,146,247,2295,2325,14,388,80,1104,754,1685,2023,22,2181,395,488,337,363,475,614,1280,226,135,366,36,725,634,35,143,1385,279,170,13
-1.1315983345381757,0.42856142165780864,2.938995264788679,1.707357730711625,0.6741288888174748,1.3103129401771128,0.41264038385623686,0.4601935811647347,1.805183895274069,1.1714327633031296,-1.0360339359435122,-1.1074820632844848,3.4383036215791014,0.7329693277559037,2.4025173766417525,-0.1007594861270674,0.18204184259460307,-0.44729726533392017,-0.6976683628564239,3.2506107876916754,-0.851816319929439,0.7183502411380084,0.522633995537609,0.8618984355820165,0.7764689191291888,0.5534510197557548,0.33196227773033055,-0.19380576235625954,1.2854711855638465,1.889836756325383,0.7764689191291888,2.9768207877432644,0.2158976081565213,0.2991791157749035,2.9843329816197044,1.8477745387244804,-0.2507823308904216,1.053540441532829,1.6629614855267152,3.45129403999315
2,454
Mitochondrial carrier protein [IPR002067]
7
8
2.653563
0.007965
P05141,O43808,P12235,P12236,Q6NUK1,Q9UJS0,Q9HC21
Sequence
InterPro Family
interpro_family
285,168,299,175,342,250,288
168,423,285,299,175,342,288,250
1.6629614855267152,0.6592655098222254,1.026794211311183,0.9862888463465534,1.6179808316611837,0.8478026431297777,1.026794211311183,1.1714327633031296
2,454
Protein transporter activity
8
14
2.651671
0.008009
O60830,Q9NS69,Q99595,Q9Y5J9,O14925,Q9HD20,Q15388,P49755
Functions
GO Molecular function
msigdb_gomf
0,1,2,323,165,78,308,346
165,0,1308,412,346,601,816,308,557,2,78,1,498,323
1.6741147827555374,4.5070088122225345,-0.2127003983705159,0.6741288888174748,0.8336504314439626,0.36445047971555095,0.13065927350069947,0.9726826435647435,0.42856142165780864,4.326911646644879,2.4470470431650044,4.336663022143436,0.5071254977386024,0.9038514320983293
2,454
Inner mitochondrial membrane organization
10
16
2.64745
0.00811
Q13505,Q9Y5J9,Q53H12,Q9BUR5,Q5XKP0,Q9NX63,O75431,O60313,Q9Y512,O95202
Processes and pathways
GO Biological process
msigdb_gobp
97,323,426,205,240,303,422,245,284,157
245,422,1308,157,2212,97,491,426,990,240,205,1017,303,1045,284,323
1.184289682202268,0.6592655098222254,-0.2127003983705159,1.707357730711625,-0.8970390410527324,2.1991575594968427,0.522633995537609,0.6592655098222254,-0.010011590331103102,1.2225783190817734,1.3958829972159683,-0.02798234723534938,0.9862888463465534,-0.04604169644634782,1.0401928182614306,0.9038514320983293
2,454
Intracellular protein transmembrane transport
11
18
2.641066
0.008265
O96008,O60830,Q99595,O95831,O43615,O14925,Q9UGP8,O75381,P31751,Q15388,Q15629
Processes and pathways
GO Biological process
msigdb_gobp
412,0,2,160,355,165,498,335,402,308,29
165,355,0,335,1308,160,412,2120,402,1627,1663,601,308,29,512,2,1299,498
1.6741147827555374,0.8051750649785682,4.5070088122225345,0.8618984355820165,-0.2127003983705159,1.6852317773417498,0.6741288888174748,-0.7849801986775056,0.6889304882517738,-0.4071533609458661,-0.42717118320069314,0.36445047971555095,0.9726826435647435,3.102203569906441,0.4915496270065848,4.326911646644879,-0.19380576235625954,0.5071254977386024
2,454
Serine hydrolase activity
9
17
2.625767
0.008645
Q9HB40,P13798,P67812,Q5JRX3,Q4J6C6,P42785,Q16740,Q9H3G5,O43464
Functions
GO Molecular function
msigdb_gomf
164,161,37,167,295,73,74,212,272
351,272,502,454,161,2021,787,73,2199,1341,37,74,295,167,1788,212,164
0.8194413803231336,1.0668374397151672,0.4915496270065848,0.5840049324470407,1.6852317773417498,-0.6976683628564239,0.14786758317336363,2.464692228627964,-0.8743601688607926,-0.23169227715850227,2.9692910588506276,2.4558814235873045,0.9998425933519748,1.6741147827555374,-0.508336059704949,1.3472450660860968,1.6852317773417498
2,454
Lysosome
18
40
2.619671
0.008801
P50897,P11117,Q9NZJ7,Q15904,Q93050,P11279,P04062,O15118,Q9Y487,P16278,Q13510,P17900,Q14108,P10253,O43681,O75503,P54802,P61916
Processes and pathways
KEGG Pathways
msigdb_kegg
32,129,195,226,36,262,71,102,13,142,45,144,50,182,151,122,248,317
2155,1049,351,102,151,1738,122,71,552,713,638,833,182,454,129,262,2020,541,142,144,2416,32,248,614,317,1901,2353,45,50,226,477,36,467,1206,825,1567,195,1385,1831,13
-0.8294060110663698,-0.06419045128865337,0.8194413803231336,2.1608111690827836,1.7836865416843557,-0.48787858846125165,1.9622100740129906,2.4909843512906855,0.42856142165780864,0.2158976081565213,0.28267536563664253,0.1133692286956227,1.5609111596332113,0.5840049324470407,1.9313825785356158,1.1064282148367273,-0.6976683628564239,0.4444122970173833,1.8583391561768707,1.8371768966766115,-1.6764363701881217,3.0364336472060622,1.1714327633031296,0.33196227773033055,0.9177256601343565,-0.5913048144722944,-1.204872765188523,2.8227904319852435,2.702273873382328,1.2854711855638465,0.5534510197557548,2.9768207877432644,0.5687606043241162,-0.15630455409864116,0.13065927350069947,-0.3674382117784822,1.4557332011052682,-0.2507823308904216,-0.5289062519642656,3.45129403999315
2,454
Carbohydrate derivative transmembrane transporter activity
7
9
2.614161
0.008945
P05141,O43808,P12235,O00400,P12236,L0R6Q1,Q8TB61
Functions
GO Molecular function
msigdb_gomf
285,168,299,173,175,213,57
213,173,168,285,299,175,508,342,57
1.3349780380688931,1.6292815636710885,1.6629614855267152,1.026794211311183,0.9862888463465534,1.6179808316611837,0.4915496270065848,0.8478026431297777,2.610978516529192
2,454
primary active transporter
11
20
2.608541
0.009093
Q9NS69,P23634,O60888,Q8N4H5,Q9H2J7,Q15388,P16615,O75381,Q9BUN8,P20020,P05023
Functions
Panther Protein class
panther_protein_class
1,388,229,47,143,308,146,335,84,247,217
229,335,1308,412,217,563,2330,1813,146,247,388,488,308,664,47,84,143,1449,1299,1
1.2729833260513288,0.8618984355820165,-0.2127003983705159,0.6741288888174748,1.3103129401771128,0.41264038385623686,-1.1315983345381757,-0.5289062519642656,1.805183895274069,1.1714327633031296,0.7329693277559037,0.522633995537609,0.9726826435647435,0.2660959890242387,2.751016824478013,2.3664570959280136,1.8477745387244804,-0.2892607576646261,-0.19380576235625954,4.336663022143436
2,454
Lytic vacuole organization
7
18
2.60412
0.009211
P50897,P11117,P04062,Q14108,P10253,O75503,P54802
Processes and pathways
GO Biological process
msigdb_gobp
32,129,71,50,182,122,248
2155,351,122,71,638,182,129,542,32,738,248,659,50,847,547,824,1044,479
-0.8294060110663698,0.8194413803231336,1.9622100740129906,2.4909843512906855,0.28267536563664253,1.5609111596332113,1.9313825785356158,0.4444122970173833,3.0364336472060622,0.19900919256781674,1.1714327633031296,0.2660959890242387,2.702273873382328,0.1133692286956227,0.4444122970173833,0.13065927350069947,-0.04604169644634782,0.5534510197557548
2,454
Pink1 prkn mediated mitophagy
7
9
2.597561
0.009389
Q9NS69,P21796,Q8N4H5,O95140,Q15388,Q13501,Q8IWA4
Processes and pathways
Reactome Pathways
msigdb_reactome
1,14,47,273,308,404,181
1308,273,412,14,404,308,181,47,1
-0.2127003983705159,1.0668374397151672,0.6741288888174748,3.4383036215791014,0.6889304882517738,0.9726826435647435,1.572401341063591,2.751016824478013,4.336663022143436
2,454
Lipid localization
22
54
2.595266
0.009452
Q9BQE5,Q14849,Q9UHB6,Q9Y679,Q99720,P17900,P31751,P28288,Q9H6V9,O43808,Q8WTV0,Q14108,Q14534,P61916,Q9NZJ7,P23786,P04062,Q9BUR5,P08183,O15118,Q86Y82,O43772
Processes and pathways
GO Biological process
msigdb_gobp
3,5,392,394,12,144,402,277,34,168,46,50,190,317,195,197,71,205,90,102,367,114
420,2435,102,924,114,168,784,2264,1541,832,1810,71,2366,1811,638,1965,90,620,144,1103,1057,197,277,402,1265,507,928,317,1029,2001,50,190,5,847,627,367,2415,46,1378,12,3,1479,205,1706,1248,2188,1381,34,195,1301,392,520,592,394
0.6592655098222254,-2.0258318051816477,2.1608111690827836,0.04337709946176049,2.0230322589366674,1.6629614855267152,0.14786758317336363,-0.9891352838762909,-0.3674382117784822,0.1133692286956227,-0.5289062519642656,2.4909843512906855,-1.279574662903545,-0.5289062519642656,0.28267536563664253,-0.6547605908794988,2.2838588768570314,0.31560787666756207,1.8371768966766115,-0.1007594861270674,-0.06419045128865337,1.4319175188017423,1.053540441532829,0.6889304882517738,-0.19380576235625954,0.4915496270065848,0.04337709946176049,0.9177256601343565,-0.04604169644634782,-0.6761532333776855,2.702273873382328,1.4911509912268668,3.7597378659854743,0.1133692286956227,0.31560787666756207,0.7764689191291888,-1.5937499890522795,2.7751176885302846,-0.2507823308904216,3.4642312200666168,4.125008978537356,-0.3086510615816659,1.3958829972159683,-0.44729726533392017,-0.17500744981820085,-0.851816319929439,-0.2507823308904216,2.9918277160543005,1.4557332011052682,-0.19380576235625954,0.7329693277559037,0.4915496270065848,0.3805855015225713,0.7329693277559037
2,454
Organic hydroxy compound metabolic process
25
84
2.587683
0.009662
Q9BQE5,Q14849,P37268,P28288,P16930,P48449,P05091,P14324,Q13510,Q8WTV0,Q14739,Q8NBN7,P51648,Q16850,Q14534,O15269,P61916,P04062,P05067,Q9UBM7,P38435,Q10713,O15118,P16435,P21964
Processes and pathways
GO Biological process
msigdb_gobp
3,5,10,277,162,291,298,171,45,46,52,185,59,61,190,316,317,71,199,201,218,223,102,103,123
2413,102,316,1452,958,1487,423,2313,1226,654,2064,336,670,1809,71,1003,199,298,2302,1310,2324,171,2066,1743,103,162,1862,123,1103,1057,277,945,2425,10,218,2416,1106,613,291,2423,1082,2073,578,1999,1749,59,1969,1586,2336,317,2001,2406,223,45,2002,190,52,5,490,374,745,61,514,185,648,46,824,1378,2269,825,2013,1936,3,591,1447,1248,1507,1731,201,392,952,1573,667,2327
-1.5937499890522795,2.1608111690827836,0.9177256601343565,-0.3086510615816659,0.00787137682826172,-0.32814340269650955,0.6592655098222254,-1.0835170684061923,-0.17500744981820085,0.2660959890242387,-0.7410713309240917,0.8618984355820165,0.2494403407682528,-0.5289062519642656,2.4909843512906855,-0.02798234723534938,1.4199477449748363,0.9862888463465534,-1.059701599588804,-0.2127003983705159,-1.1074820632844848,1.6405450993859982,-0.7410713309240917,-0.48787858846125165,2.1608111690827836,1.6852317773417498,-0.5703894458091343,1.9519654921535743,-0.1007594861270674,-0.06419045128865337,1.053540441532829,0.02566734622848883,-1.8182597407279888,3.48994747351802,1.3103129401771128,-1.6764363701881217,-0.1007594861270674,0.33196227773033055,1.013344258369898,-1.7894811458568527,-0.08242943604018182,-0.7410713309240917,0.3966486055076561,-0.6761532333776855,-0.48787858846125165,2.5941024654889833,-0.6547605908794988,-0.3872427236161005,-1.1558676625729167,0.9177256601343565,-0.6761532333776855,-1.5395856690495455,1.2979142914342985,2.8227904319852435,-0.6761532333776855,1.4911509912268668,2.685863124657544,3.7597378659854743,0.522633995537609,0.7620282155096825,0.19900919256781674,2.585631778102509,0.4915496270065848,1.5378147610241326,0.28267536563664253,2.7751176885302846,0.13065927350069947,-0.2507823308904216,-0.9891352838762909,0.13065927350069947,-0.6761532333776855,-0.6123376390093992,4.125008978537356,0.3805855015225713,-0.2892607576646261,-0.17500744981820085,-0.32814340269650955,-0.4675326981198081,1.4199477449748363,0.7329693277559037,0.02566734622848883,-0.3674382117784822,0.2660959890242387,-1.1074820632844848
2,454
Ion transport
57
154
2.586573
0.009694
P23634,Q9H2D1,P00403,Q658P3,Q15041,P51790,P21796,Q9H2J7,P16615,Q9UDW1,P28288,P45880,O43681,Q9UM00,Q02978,Q70HW3,O95202,Q9HC21,P05141,Q8N4V1,O96008,Q9C0H2,O75027,O75964,O15173,O43808,Q9Y277,P12235,O75746,O00400,P12236,Q9UBX3,P51809,Q8TB61,O75915,Q9NZJ7,P05067,Q13423,Q9HD20,P24539,P55011,P53985,Q6NUK1,Q9Y619,P08183,P05023,Q9UJS0,O76024,O75844,Q9UHG3,Q6P4Q7,O43772,P13073,P56134,O60831,P20020,Q99623
Processes and pathways
GO Biological process
msigdb_gobp
388,6,263,135,138,395,14,143,146,19,277,22,151,279,281,153,157,288,285,33,412,35,411,40,39,168,170,299,423,173,175,48,434,57,319,195,199,72,78,80,337,214,342,350,90,217,250,231,106,112,366,114,115,363,121,247,382
2329,173,710,500,2263,39,924,151,1051,114,168,905,2116,121,411,2207,693,2264,1741,423,106,319,551,40,231,157,412,263,884,2366,906,217,563,199,285,671,529,1811,1993,1684,90,607,576,766,834,1310,299,175,115,629,620,146,886,247,440,2295,2325,2401,14,388,80,1431,1104,1621,277,1339,860,656,1459,1105,754,1685,2023,508,2198,22,2072,1340,2181,718,395,434,214,720,488,337,363,475,660,614,1520,601,1463,580,616,1670,1901,1671,281,1435,1240,2167,1275,72,1405,1134,2168,892,1280,138,1784,989,664,845,135,342,627,366,153,1324,1246,33,57,723,628,920,2269,382,725,1208,634,35,2258,6,143,1449,288,78,195,48,19,1421,112,952,1385,250,592,279,2061,651,170,535,1045,350
-1.1315983345381757,1.6292815636710885,0.2158976081565213,0.4915496270065848,-0.9891352838762909,2.938995264788679,0.04337709946176049,1.7836865416843557,-0.06419045128865337,2.0230322589366674,1.6629614855267152,0.06100140790540697,-0.7849801986775056,1.972423639877387,0.6741288888174748,-0.8970390410527324,0.23270776762766546,-0.9891352838762909,-0.48787858846125165,0.6592655098222254,2.1511554521015115,0.9038514320983293,0.42856142165780864,2.938995264788679,1.260450413484564,1.707357730711625,0.6741288888174748,1.0932809768597807,0.07854103289676595,-1.279574662903545,0.06100140790540697,1.3103129401771128,0.41264038385623686,1.4199477449748363,1.026794211311183,0.2494403407682528,0.4601935811647347,-0.5289062519642656,-0.6761532333776855,-0.44729726533392017,2.2838588768570314,0.34824294069161715,0.3966486055076561,0.16499487134818433,0.1133692286956227,-0.2127003983705159,0.9862888463465534,1.6179808316611837,2.0230322589366674,0.2991791157749035,0.31560787666756207,1.805183895274069,0.07854103289676595,1.1714327633031296,0.6293514881429343,-1.0360339359435122,-1.1074820632844848,-1.5127841056693392,3.4383036215791014,0.7329693277559037,2.4025173766417525,-0.2892607576646261,-0.1007594861270674,-0.4071533609458661,1.053540441532829,-0.23169227715850227,0.09599672590438624,0.2660959890242387,-0.3086510615816659,-0.1007594861270674,0.18204184259460307,-0.44729726533392017,-0.6976683628564239,0.4915496270065848,-0.8743601688607926,3.2506107876916754,-0.7410713309240917,-0.23169227715850227,-0.851816319929439,0.2158976081565213,0.7183502411380084,0.6443398713807004,1.3349780380688931,0.2158976081565213,0.522633995537609,0.8618984355820165,0.7764689191291888,0.5534510197557548,0.2660959890242387,0.33196227773033055,-0.34773878122711316,0.36445047971555095,-0.3086510615816659,0.3966486055076561,0.33196227773033055,-0.42717118320069314,-0.5913048144722944,-0.42717118320069314,1.0401928182614306,-0.2892607576646261,-0.17500744981820085,-0.8294060110663698,-0.19380576235625954,2.4909843512906855,-0.26997150484729665,-0.11918144832285707,-0.8294060110663698,0.07854103289676595,-0.19380576235625954,1.8688709393675171,-0.508336059704949,-0.010011590331103102,0.2660959890242387,0.1133692286956227,1.889836756325383,0.8478026431297777,0.31560787666756207,0.7764689191291888,1.7293410708596129,-0.2127003983705159,-0.17500744981820085,3.0290421086807306,2.610978516529192,0.2158976081565213,0.31560787666756207,0.06100140790540697,-0.9891352838762909,0.7475285012988273,0.2158976081565213,-0.15630455409864116,0.2991791157749035,2.9843329816197044,-0.9659009950668074,3.6277474447573046,1.8477745387244804,-0.2892607576646261,1.026794211311183,2.4470470431650044,1.4557332011052682,2.726736385136414,3.3053793135556817,-0.26997150484729665,2.0728909396765256,0.02566734622848883,-0.2507823308904216,1.1714327633031296,0.3805855015225713,1.053540441532829,-0.7193072862402492,0.28267536563664253,1.6629614855267152,0.4601935811647347,-0.04604169644634782,0.8336504314439626
2,454
Sterol metabolism
9
17
2.581868
0.009827
O15118,P04062,P37268,Q9UBM7,P14324,Q14739,Q15392,Q16850,P61916
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
102,71,10,201,171,52,374,61,317
102,654,670,71,171,10,317,2001,2406,2002,52,374,745,61,201,392,952
2.1608111690827836,0.2660959890242387,0.2494403407682528,2.4909843512906855,1.6405450993859982,3.48994747351802,0.9177256601343565,-0.6761532333776855,-1.5395856690495455,-0.6761532333776855,2.685863124657544,0.7620282155096825,0.19900919256781674,2.585631778102509,1.4199477449748363,0.7329693277559037,0.02566734622848883
2,454
Purine nucleotide transmembrane transporter activity
6
9
2.571194
0.010135
P05141,O43808,P12235,O00400,P12236,Q8TB61
Functions
GO Molecular function
msigdb_gomf
285,168,299,173,175,57
173,924,168,285,299,175,508,342,57
1.6292815636710885,0.04337709946176049,1.6629614855267152,1.026794211311183,0.9862888463465534,1.6179808316611837,0.4915496270065848,0.8478026431297777,2.610978516529192
2,454
Purine nucleotide transport
6
9
2.571194
0.010135
P05141,O43808,P12235,O00400,P12236,Q8TB61
Processes and pathways
GO Biological process
msigdb_gobp
285,168,299,173,175,57
173,924,168,285,299,175,508,342,57
1.6292815636710885,0.04337709946176049,1.6629614855267152,1.026794211311183,0.9862888463465534,1.6179808316611837,0.4915496270065848,0.8478026431297777,2.610978516529192
2,454
Mitochondrial membrane organization
18
38
2.559853
0.010472
P05141,Q9NS69,Q13505,Q9Y5J9,Q53H12,O14737,P12235,Q16891,O75431,Q9BUR5,Q9NX63,O95140,Q5XKP0,Q8IWA4,P45880,O60313,Q9Y512,O95202
Processes and pathways
GO Biological process
msigdb_gobp
285,1,97,323,426,330,299,491,422,205,303,273,240,181,22,245,284,157
2155,330,245,422,1308,273,157,1003,285,1184,1490,299,1339,1581,2071,2212,1106,22,1163,1497,1129,97,491,512,426,990,240,181,799,848,205,1,1017,303,953,1045,284,323
-0.8294060110663698,0.8759382244797788,1.184289682202268,0.6592655098222254,-0.2127003983705159,1.0668374397151672,1.707357730711625,-0.02798234723534938,1.026794211311183,-0.15630455409864116,-0.32814340269650955,0.9862888463465534,-0.23169227715850227,-0.3872427236161005,-0.7410713309240917,-0.8970390410527324,-0.1007594861270674,3.2506107876916754,-0.13769618095212716,-0.32814340269650955,-0.11918144832285707,2.1991575594968427,0.522633995537609,0.4915496270065848,0.6592655098222254,-0.010011590331103102,1.2225783190817734,1.572401341063591,0.14786758317336363,0.1133692286956227,1.3958829972159683,4.336663022143436,-0.02798234723534938,0.9862888463465534,0.02566734622848883,-0.04604169644634782,1.0401928182614306,0.9038514320983293
2,454
Lipid metabolism
33
92
2.55916
0.010493
Q96N66,A1L0T0,P09960,P48651,P37268,Q53GQ0,P17900,Q9H7Z7,Q96G23,Q9NZ01,Q06136,Q9NPH0,Q9H6V9,P48449,P14324,Q13510,O95864,Q14739,Q9UG56,Q9P035,P51648,Q16850,O15269,O00116,P23786,P04062,Q9UBM7,Q8NF37,Q13011,Q8NHP8,O15118,O00767,O95470
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
130,257,133,137,10,145,144,148,21,149,24,159,34,291,171,45,305,52,312,187,59,61,316,196,197,71,201,83,94,96,102,238,116
257,196,1254,2435,238,1255,102,316,1426,1124,654,116,832,305,670,71,2447,133,2444,2449,171,655,144,197,1338,1657,2179,2265,1265,507,10,1686,2416,483,1106,1433,291,137,1546,1082,738,59,413,1969,1690,317,2001,2406,24,94,2452,45,2002,52,490,582,1320,406,374,745,681,61,1595,145,627,2339,485,83,96,517,453,21,130,467,2013,370,685,2445,873,1447,1643,34,148,159,1507,149,187,201,312,392,952,1302
1.132575350613476,1.4319175188017423,-0.19380576235625954,-2.0258318051816477,1.2225783190817734,-0.19380576235625954,2.1608111690827836,0.9177256601343565,-0.2892607576646261,-0.11918144832285707,0.2660959890242387,2.0129711959011636,0.1133692286956227,0.9726826435647435,0.2494403407682528,2.4909843512906855,-3.3479781746602133,1.9002711628395195,-2.722727992482984,-3.609229281021436,1.6405450993859982,0.2660959890242387,1.8371768966766115,1.4319175188017423,-0.23169227715850227,-0.42717118320069314,-0.851816319929439,-0.9891352838762909,-0.19380576235625954,0.4915496270065848,3.48994747351802,-0.44729726533392017,-1.6764363701881217,0.5380756588239767,-0.1007594861270674,-0.2892607576646261,1.013344258369898,1.8793700770320063,-0.3674382117784822,-0.08242943604018182,0.19900919256781674,2.5941024654889833,0.6741288888174748,-0.6547605908794988,-0.44729726533392017,0.9177256601343565,-0.6761532333776855,-1.5395856690495455,3.194884274897394,2.237068567781521,-4.84595143444432,2.8227904319852435,-0.6761532333776855,2.685863124657544,0.522633995537609,0.3966486055076561,-0.2127003983705159,0.6889304882517738,0.7620282155096825,0.19900919256781674,0.2494403407682528,2.585631778102509,-0.3872427236161005,1.8371768966766115,0.31560787666756207,-1.1558676625729167,0.5380756588239767,2.3755090350781054,2.2086757692141044,0.4915496270065848,0.5991845180612049,3.264391530678441,1.9313825785356158,0.5687606043241162,-0.6761532333776855,0.7764689191291888,0.2494403407682528,-2.722727992482984,0.09599672590438624,-0.2892607576646261,-0.4071533609458661,2.9918277160543005,1.805183895274069,1.696312687795655,-0.32814340269650955,1.805183895274069,1.5262080593683736,1.4199477449748363,0.9453113558034467,0.7329693277559037,0.02566734622848883,-0.19380576235625954
2,454
mitochondria
7
11
2.558741
0.010505
Q969Q5,Q9NR31,Q9Y277,P21796,O95140,Q8IWA4,P45880
Localization
OpenCell Localization
opencell_localization
194,261,170,14,273,181,22
1308,273,14,22,2299,308,181,194,261,1017,170
-0.2127003983705159,1.0668374397151672,3.4383036215791014,3.2506107876916754,-1.0360339359435122,0.9726826435647435,1.572401341063591,1.4557332011052682,1.1195262258501388,-0.02798234723534938,1.6629614855267152
2,454
Cellular ion homeostasis
32
67
2.538389
0.011136
O75880,P23634,P51790,Q9Y487,P09601,P16615,P06576,Q9UM00,Q96A33,Q96AX1,O95202,P50897,O75027,Q93050,P51572,Q9Y639,P05026,P05067,P78417,Q9HD20,Q9UJZ1,P55011,P05023,Q15904,O76024,P54709,P20020,P61421,Q16891,Q96HE7,O75503,P13693
Processes and pathways
GO Biological process
msigdb_gobp
387,388,395,13,17,146,529,279,155,547,157,32,411,36,180,447,563,199,580,78,592,337,217,226,231,488,247,614,491,628,122,629
2155,1049,2263,2116,411,122,387,2362,231,157,1002,884,217,563,199,529,638,1684,730,17,767,629,1618,146,886,247,1056,388,1621,1946,860,2023,2198,32,738,180,395,488,337,614,1463,580,1670,2168,771,989,226,491,1324,1246,36,155,547,628,920,853,725,1569,78,1421,1385,592,1536,279,13,1045,447
-0.8294060110663698,-0.06419045128865337,-0.9891352838762909,-0.7849801986775056,0.6741288888174748,1.9622100740129906,0.7329693277559037,-1.254512242689449,1.260450413484564,1.707357730711625,-0.02798234723534938,0.07854103289676595,1.3103129401771128,0.41264038385623686,1.4199477449748363,0.4601935811647347,0.28267536563664253,-0.44729726533392017,0.19900919256781674,3.312159535019784,0.16499487134818433,0.2991791157749035,-0.4071533609458661,1.805183895274069,0.07854103289676595,1.1714327633031296,-0.06419045128865337,0.7329693277559037,-0.4071533609458661,-0.63348914849447,0.09599672590438624,-0.6976683628564239,-0.8743601688607926,3.0364336472060622,0.19900919256781674,1.572401341063591,0.7183502411380084,0.522633995537609,0.8618984355820165,0.33196227773033055,-0.3086510615816659,0.3966486055076561,-0.42717118320069314,-0.8294060110663698,0.16499487134818433,-0.010011590331103102,1.2854711855638465,0.522633995537609,-0.2127003983705159,-0.17500744981820085,2.9768207877432644,1.7293410708596129,0.4444122970173833,0.31560787666756207,0.06100140790540697,0.1133692286956227,0.2158976081565213,-0.3674382117784822,2.4470470431650044,-0.26997150484729665,-0.2507823308904216,0.3805855015225713,-0.34773878122711316,1.053540441532829,3.45129403999315,-0.04604169644634782,0.6293514881429343
2,454
Intrinsic component of golgi membrane
6
8
2.537751
0.011157
Q5W0Z9,Q9Y282,O15258,O43505,L0R6Q1,Q8TB61
Localization
GO Cellular component
msigdb_gocc
134,70,233,268,213,57
213,233,268,1845,134,375,57,70
1.3349780380688931,1.247872145516247,1.08008416772596,-0.5495903224499785,1.9002711628395195,0.7620282155096825,2.610978516529192,2.517068436125271
2,454
Exocytic vesicle
14
28
2.531214
0.011367
P50897,Q92905,P11279,P05067,O76024,Q86Y82,P51790,P20020,Q92542,P61026,O15400,O43760,P61020,Q96A57
Localization
GO Cellular component
msigdb_gocc
32,353,262,199,231,367,395,247,147,306,280,56,219,192
710,562,280,56,231,199,262,247,809,1621,32,738,2163,395,1462,219,306,614,1469,679,795,989,367,147,353,192,494,438
0.2158976081565213,0.41264038385623686,1.0401928182614306,2.610978516529192,1.260450413484564,1.4199477449748363,1.1064282148367273,1.1714327633031296,0.13065927350069947,-0.4071533609458661,3.0364336472060622,0.19900919256781674,-0.8294060110663698,0.7183502411380084,-0.3086510615816659,1.3103129401771128,0.9726826435647435,0.33196227773033055,-0.3086510615816659,0.2494403407682528,0.14786758317336363,-0.010011590331103102,0.7764689191291888,1.805183895274069,0.8194413803231336,1.4793854803467268,0.522633995537609,0.6443398713807004
2,454
Delusions
6
15
2.53027
0.011397
Q9NZJ7,Q9BQE5,P04062,O43681,Q9UJS0,P21964
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
195,3,71,151,250,123
151,71,123,1495,2198,1865,868,1192,776,1350,3,296,195,1535,250
1.7836865416843557,2.4909843512906855,1.9519654921535743,-0.32814340269650955,-0.8743601688607926,-0.5703894458091343,0.09599672590438624,-0.15630455409864116,0.16499487134818433,-0.23169227715850227,4.125008978537356,0.9998425933519748,1.4557332011052682,-0.34773878122711316,1.1714327633031296
2,454
Cholesterol metabolism with bloch and kandutschrussell pathways
9
18
2.529114
0.011435
P48449,P37268,Q9UBM7,P14324,O00767,O95864,Q14739,Q16850,Q14534
Processes and pathways
WikiPathways
msigdb_wp
291,10,201,171,238,305,52,61,190
238,1426,832,305,171,1265,10,291,1546,2406,2002,190,52,374,745,61,1566,201
1.2225783190817734,-0.2892607576646261,0.1133692286956227,0.9726826435647435,1.6405450993859982,-0.19380576235625954,3.48994747351802,1.013344258369898,-0.3674382117784822,-1.5395856690495455,-0.6761532333776855,1.4911509912268668,2.685863124657544,0.7620282155096825,0.19900919256781674,2.585631778102509,-0.3674382117784822,1.4199477449748363
2,454
secondary carrier transporter
8
10
2.523733
0.011612
Q02978,Q6NT16,O00400,P55011,Q9UBX3,Q9UJS0,O95202,Q8TB61
Functions
Panther Protein class
panther_protein_class
281,139,173,337,48,250,157,57
173,423,157,337,281,139,627,57,48,250
1.6292815636710885,0.6592655098222254,1.707357730711625,0.8618984355820165,1.0401928182614306,1.8688709393675171,0.31560787666756207,2.610978516529192,2.726736385136414,1.1714327633031296
2,454
Cation transmembrane transport
44
94
2.517419
0.011822
O00483,P23634,P00403,P51790,P21796,Q9H2J7,P16615,Q9UDW1,P06576,Q9UM00,Q70HW3,O95202,Q9HC21,P05141,Q8N4V1,O75027,O75964,P12235,O00400,O75947,P05026,P20674,P05067,Q13423,P08574,P78417,Q9HD20,Q9UJZ1,P24539,P55011,P61619,Q9Y619,P56385,P05023,P08195,Q00325,P54709,P61421,Q6P4Q7,O43772,P13073,P56134,P20020,Q99623
Processes and pathways
GO Biological process
msigdb_gobp
500,388,263,395,14,143,146,19,529,279,153,157,288,285,33,411,40,299,173,551,563,440,199,72,576,580,78,592,80,337,601,350,475,217,607,616,488,614,366,114,115,363,247,382
173,500,2263,1051,114,2116,411,693,1741,551,40,157,263,217,563,199,285,671,529,1811,1993,1684,607,576,766,1310,299,115,146,886,247,440,2295,2325,2401,14,388,80,1104,1621,1339,860,656,754,1685,2023,2198,1340,2181,718,395,488,337,363,475,614,601,1463,580,616,1670,1435,1240,2167,1275,72,2168,892,989,664,366,153,1324,1246,33,723,628,920,2269,382,725,1208,2258,143,1449,288,78,19,1421,1385,592,279,1045,350
1.6292815636710885,0.4915496270065848,-0.9891352838762909,-0.06419045128865337,2.0230322589366674,-0.7849801986775056,0.6741288888174748,0.23270776762766546,-0.48787858846125165,0.42856142165780864,2.938995264788679,1.707357730711625,1.0932809768597807,1.3103129401771128,0.41264038385623686,1.4199477449748363,1.026794211311183,0.2494403407682528,0.4601935811647347,-0.5289062519642656,-0.6761532333776855,-0.44729726533392017,0.34824294069161715,0.3966486055076561,0.16499487134818433,-0.2127003983705159,0.9862888463465534,2.0230322589366674,1.805183895274069,0.07854103289676595,1.1714327633031296,0.6293514881429343,-1.0360339359435122,-1.1074820632844848,-1.5127841056693392,3.4383036215791014,0.7329693277559037,2.4025173766417525,-0.1007594861270674,-0.4071533609458661,-0.23169227715850227,0.09599672590438624,0.2660959890242387,0.18204184259460307,-0.44729726533392017,-0.6976683628564239,-0.8743601688607926,-0.23169227715850227,-0.851816319929439,0.2158976081565213,0.7183502411380084,0.522633995537609,0.8618984355820165,0.7764689191291888,0.5534510197557548,0.33196227773033055,0.36445047971555095,-0.3086510615816659,0.3966486055076561,0.33196227773033055,-0.42717118320069314,-0.2892607576646261,-0.17500744981820085,-0.8294060110663698,-0.19380576235625954,2.4909843512906855,-0.8294060110663698,0.07854103289676595,-0.010011590331103102,0.2660959890242387,0.7764689191291888,1.7293410708596129,-0.2127003983705159,-0.17500744981820085,3.0290421086807306,0.2158976081565213,0.31560787666756207,0.06100140790540697,-0.9891352838762909,0.7475285012988273,0.2158976081565213,-0.15630455409864116,-0.9659009950668074,1.8477745387244804,-0.2892607576646261,1.026794211311183,2.4470470431650044,3.3053793135556817,-0.26997150484729665,-0.2507823308904216,0.3805855015225713,1.053540441532829,-0.04604169644634782,0.8336504314439626
2,454
Mitophagy
7
11
2.515056
0.011901
Q9NS69,P21796,Q8N4H5,O95140,Q15388,Q13501,Q8IWA4
Processes and pathways
Reactome Pathways
msigdb_reactome
1,14,47,273,308,404,181
1308,273,412,14,889,404,308,181,47,1679,1
-0.2127003983705159,1.0668374397151672,0.6741288888174748,3.4383036215791014,0.07854103289676595,0.6889304882517738,0.9726826435647435,1.572401341063591,2.751016824478013,-0.42717118320069314,4.336663022143436
2,454
Mitochondrial envelope
95
241
2.513777
0.011945
O60830,Q9NS69,Q99595,Q9H061,Q9H2D1,Q567V2,O43169,P21796,Q8WWV3,P09601,Q9Y2R0,Q9UDW1,P45880,P14406,O43676,Q69YU5,O75964,Q8WY22,Q8N4H5,Q9UBX3,Q9BSK2,O14949,Q96A26,Q9UDX5,P22830,Q13423,P24539,Q7Z7H8,Q13505,O43772,P13073,Q8IUX1,Q70HW3,O95202,O95831,O14925,Q9Y277,P12236,O00264,Q8IWA4,Q8NBN7,Q9NPL8,Q9NZJ7,P23786,Q9BUR5,Q16134,Q10713,Q5XKP0,O60313,Q86Y39,Q9UJS0,Q6DKK2,P00403,P53701,O95140,O43464,Q02978,Q9Y512,Q9HC21,P05141,P22695,O00165,P12235,Q9NX63,Q15388,Q9NVI7,Q9UG56,O00584,Q96TA2,Q9Y5J9,Q96IX5,Q9BWH2,Q9Y320,Q6NUK1,Q9Y375,Q9Y619,O75306,O43615,P56134,O15228,Q9NX14,Q99623,O75880,Q9BRJ2,P21912,P82933,Q6PI78,Q9NR28,Q9Y6M9,O96008,O75027,Q53H12,Q9Y6C9,O75746,O75431
Localization
GO Cellular component
msigdb_gocc
0,1,2,4,6,7,8,14,15,17,18,19,22,26,27,30,40,41,47,48,51,55,58,64,67,72,80,82,97,114,115,140,153,157,160,165,170,175,179,181,185,188,195,197,205,216,223,240,245,249,250,255,263,265,273,272,281,284,288,285,294,297,299,303,308,310,312,313,318,323,328,333,334,342,343,350,356,355,363,362,384,382,387,400,397,403,407,416,419,412,411,426,431,423,422
297,179,710,500,313,2435,165,55,362,1858,8,272,355,27,114,245,1426,0,411,693,356,422,1741,1769,1963,943,423,387,551,40,1889,1308,273,503,157,1360,832,160,412,670,263,695,285,529,2302,576,2275,1490,17,1616,766,2120,2444,299,175,907,115,26,732,2376,1655,1775,1776,440,14,397,294,67,733,197,80,1104,2159,1339,1458,656,1265,1006,473,598,754,1495,2212,483,542,613,22,2181,1924,1082,2162,1498,1129,1548,1750,265,908,658,1690,363,475,1191,790,1273,1012,963,987,403,616,1501,281,816,223,1467,867,72,97,1696,2299,1698,308,916,216,1137,845,491,512,426,7,990,1196,513,2008,240,30,255,2054,342,935,407,153,1347,82,249,140,181,799,848,1246,590,647,47,775,185,557,1702,15,41,1035,970,1604,58,1874,2149,871,453,2081,1093,919,1038,1679,328,1350,318,853,2269,437,2,382,725,585,400,51,205,2445,333,873,777,941,560,1297,4,1211,6,686,1040,1449,2152,1325,1299,288,1532,827,188,1731,416,1,1607,1017,310,1609,384,303,829,195,979,468,2060,48,19,64,312,878,250,592,170,18,857,334,690,343,1832,996,495,1177,1045,284,323,350,431,419
0.9862888463465534,1.5838531632440178,0.2158976081565213,0.4915496270065848,0.9315455033685286,-2.0258318051816477,1.6741147827555374,2.652792387509817,0.7764689191291888,-0.5703894458091343,3.5596030781502175,1.0668374397151672,0.8051750649785682,3.123830761702728,2.0230322589366674,1.184289682202268,-0.2892607576646261,4.5070088122225345,0.6741288888174748,0.23270776762766546,0.8051750649785682,0.6592655098222254,-0.48787858846125165,-0.508336059704949,-0.6547605908794988,0.02566734622848883,0.6592655098222254,0.7329693277559037,0.42856142165780864,2.938995264788679,-0.5913048144722944,-0.2127003983705159,1.0668374397151672,0.4915496270065848,1.707357730711625,-0.2507823308904216,0.1133692286956227,1.6852317773417498,0.6741288888174748,0.2494403407682528,1.0932809768597807,0.23270776762766546,1.026794211311183,0.4601935811647347,-1.059701599588804,0.3966486055076561,-1.0125123853599192,-0.32814340269650955,3.312159535019784,-0.4071533609458661,0.16499487134818433,-0.7849801986775056,-2.722727992482984,0.9862888463465534,1.6179808316611837,0.06100140790540697,2.0230322589366674,3.1310075169748237,0.19900919256781674,-1.330194747186479,-0.42717118320069314,-0.508336059704949,-0.508336059704949,0.6293514881429343,3.4383036215791014,0.7036707826264457,0.9998425933519748,2.5257174263669264,0.19900919256781674,1.4319175188017423,2.4025173766417525,-0.1007594861270674,-0.8294060110663698,-0.23169227715850227,-0.3086510615816659,0.2660959890242387,-0.19380576235625954,-0.02798234723534938,0.5534510197557548,0.36445047971555095,0.18204184259460307,-0.32814340269650955,-0.8970390410527324,0.5380756588239767,0.4444122970173833,0.33196227773033055,3.2506107876916754,-0.851816319929439,-0.6123376390093992,-0.08242943604018182,-0.8294060110663698,-0.32814340269650955,-0.11918144832285707,-0.3674382117784822,-0.48787858846125165,1.0932809768597807,0.06100140790540697,0.2660959890242387,-0.44729726533392017,0.7764689191291888,0.5534510197557548,-0.15630455409864116,0.14786758317336363,-0.19380576235625954,-0.02798234723534938,0.00787137682826172,-0.010011590331103102,0.6889304882517738,0.33196227773033055,-0.32814340269650955,1.0401928182614306,0.13065927350069947,1.2979142914342985,-0.3086510615816659,0.09599672590438624,2.4909843512906855,2.1991575594968427,-0.44729726533392017,-1.0360339359435122,-0.44729726533392017,0.9726826435647435,0.06100140790540697,1.3226674254457509,-0.11918144832285707,0.1133692286956227,0.522633995537609,0.4915496270065848,0.6592655098222254,3.5783352045461188,-0.010011590331103102,-0.15630455409864116,0.4915496270065848,-0.6761532333776855,1.2225783190817734,3.102203569906441,1.1455759264064622,-0.7193072862402492,0.8478026431297777,0.04337709946176049,0.6889304882517738,1.7293410708596129,-0.23169227715850227,2.3845363121916474,1.1714327633031296,1.8688709393675171,1.572401341063591,0.14786758317336363,0.1133692286956227,-0.17500744981820085,0.3805855015225713,0.28267536563664253,2.751016824478013,0.16499487134818433,1.5378147610241326,0.42856142165780864,-0.44729726533392017,3.4317883207651376,2.931376710300793,-0.04604169644634782,0.00787137682826172,-0.3872427236161005,2.6025513436648535,-0.5703894458091343,-0.8071277827585696,0.09599672590438624,0.5991845180612049,-0.7410713309240917,-0.08242943604018182,0.06100140790540697,-0.04604169644634782,-0.42717118320069314,0.8899224210436362,-0.23169227715850227,0.9177256601343565,0.1133692286956227,-0.9891352838762909,0.6443398713807004,4.326911646644879,0.7475285012988273,0.2158976081565213,0.3966486055076561,0.7036707826264457,2.702273873382328,1.3958829972159683,-2.722727992482984,0.8759382244797788,0.09599672590438624,0.16499487134818433,0.04337709946176049,0.42856142165780864,-0.19380576235625954,3.7831470025227314,-0.15630455409864116,3.6277474447573046,0.2494403407682528,-0.04604169644634782,-0.2892607576646261,-0.8071277827585696,-0.2127003983705159,-0.19380576235625954,1.026794211311183,-0.34773878122711316,0.13065927350069947,1.5145620294556341,-0.4675326981198081,0.6741288888174748,4.336663022143436,-0.3872427236161005,-0.02798234723534938,0.9590236072859809,-0.3872427236161005,0.7475285012988273,0.9862888463465534,0.13065927350069947,1.4557332011052682,0.00787137682826172,0.5687606043241162,-0.7193072862402492,2.726736385136414,3.3053793135556817,2.560087810726942,0.9453113558034467,0.09599672590438624,1.1714327633031296,0.3805855015225713,1.6629614855267152,3.312159535019784,0.1133692286956227,0.8759382244797788,0.2494403407682528,0.8478026431297777,-0.5289062519642656,-0.010011590331103102,0.522633995537609,-0.13769618095212716,-0.04604169644634782,1.0401928182614306,0.9038514320983293,0.8336504314439626,0.6592655098222254,0.6741288888174748
2,454
metalloprotease
10
24
2.497016
0.012524
P55786,O43847,Q5JRX3,P22695,O75844,P42892,Q9NZ08,Q99797,Q9UIQ6,Q10713
Functions
Panther Protein class
panther_protein_class
66,132,167,294,106,77,304,211,241,223
132,1741,106,884,2303,1230,294,2098,656,77,1750,66,223,167,1064,1637,1144,318,211,560,1571,304,241,1045
1.910673480620233,-0.48787858846125165,2.1511554521015115,0.07854103289676595,-1.059701599588804,-0.17500744981820085,0.9998425933519748,-0.7629618451971119,0.2660959890242387,2.4470470431650044,-0.48787858846125165,2.5343437494190257,1.2979142914342985,1.6741147827555374,-0.06419045128865337,-0.4071533609458661,-0.11918144832285707,0.9177256601343565,1.3472450660860968,0.42856142165780864,-0.3674382117784822,0.9862888463465534,1.2098621409006676,-0.04604169644634782
2,454
Endosome membrane
22
92
2.495449
0.01258
Q14849,P11279,Q658P3,Q9Y487,Q92542,O15400,Q8N4V1,Q93050,Q14108,P61026,P10321,O00461,P42892,O14828,O75436,P61020,Q8IV08,Q15904,O15118,O15127,Q86YV9,O60831
Localization
GO Cellular component
msigdb_gocc
5,262,135,13,147,280,33,36,50,306,309,54,77,340,344,219,93,226,102,113,242,121
691,54,1049,340,102,562,113,280,1257,883,784,728,121,2264,344,2136,1579,1259,884,2366,2045,671,1811,1684,309,262,2020,809,2158,1367,755,77,864,738,2163,395,434,1462,219,306,659,614,1131,1589,1901,912,1405,1110,50,5,795,989,226,1244,2007,135,847,1141,367,242,93,33,1794,147,36,547,918,872,824,1350,1378,2085,1206,1247,2374,2445,1706,1248,650,1212,1381,1044,2042,951,1386,1766,1215,651,528,955,479,13
0.23270776762766546,2.652792387509817,-0.06419045128865337,0.8478026431297777,2.1608111690827836,0.41264038385623686,2.0629782100391028,1.0401928182614306,-0.19380576235625954,0.07854103289676595,0.14786758317336363,0.19900919256781674,1.972423639877387,-0.9891352838762909,0.8336504314439626,-0.8071277827585696,-0.3872427236161005,-0.19380576235625954,0.07854103289676595,-1.279574662903545,-0.7193072862402492,0.2494403407682528,-0.5289062519642656,-0.44729726533392017,0.9590236072859809,1.1064282148367273,-0.6976683628564239,0.13065927350069947,-0.8294060110663698,-0.2507823308904216,0.18204184259460307,2.4470470431650044,0.09599672590438624,0.19900919256781674,-0.8294060110663698,0.7183502411380084,0.6443398713807004,-0.3086510615816659,1.3103129401771128,0.9726826435647435,0.2660959890242387,0.33196227773033055,-0.11918144832285707,-0.3872427236161005,-0.5913048144722944,0.06100140790540697,-0.26997150484729665,-0.1007594861270674,2.702273873382328,3.7597378659854743,0.14786758317336363,-0.010011590331103102,1.2854711855638465,-0.17500744981820085,-0.6761532333776855,1.889836756325383,0.1133692286956227,-0.11918144832285707,0.7764689191291888,1.197099367809086,2.2464793614272396,3.0290421086807306,-0.508336059704949,1.805183895274069,2.9768207877432644,0.4444122970173833,0.06100140790540697,0.09599672590438624,0.13065927350069947,-0.23169227715850227,-0.2507823308904216,-0.7410713309240917,-0.15630455409864116,-0.17500744981820085,-1.3048014939574935,-2.722727992482984,-0.44729726533392017,-0.17500744981820085,0.28267536563664253,-0.15630455409864116,-0.2507823308904216,-0.04604169644634782,-0.6976683628564239,0.02566734622848883,-0.2507823308904216,-0.48787858846125165,-0.15630455409864116,0.28267536563664253,0.47590583856156266,0.02566734622848883,0.5534510197557548,3.45129403999315
2,454
Organelle subcompartment
102
278
2.490798
0.012746
Q9BQE5,Q14849,P37268,Q99720,P09601,P43307,Q96G23,P30519,Q06136,O95197,P07099,Q15629,P24390,Q8N4V1,P67812,O60725,Q86XL3,Q14108,Q14739,Q96KC8,O00461,Q8TB61,Q5BJF2,P51648,Q16850,Q07065,Q9Y5M8,Q9Y282,P04062,Q9HD20,Q8NF37,Q9BUN8,Q9NQC3,Q8IV08,P16435,Q8TCT9,P35613,O75844,Q9BRR6,Q9NPR9,O15127,Q9Y3B3,O95470,Q9Y4P3,P49069,Q96N66,P48651,Q15041,Q53GQ0,P16615,Q9NZ01,Q10472,Q96A33,Q03519,Q86UE4,O00400,P46977,O00264,P51572,Q9UBU6,Q9P035,Q14534,Q96A57,P57088,P05067,Q9UBV2,Q9UBM7,O43292,Q9BUR5,Q15005,P38435,Q10713,Q9NPA0,Q15904,Q6NUQ4,O76024,Q96AG4,Q9P2W9,O00767,Q9H3N1,A1L0T0,O43852,Q70UQ0,Q9NTJ5,O43464,Q9UM00,P48449,Q4J6C6,Q9NZ08,Q00765,O95864,P61026,P10321,P27824,O15269,O75915,P04843,O14880,P51571,Q9Y320,O14828,Q13724
Localization
GO Cellular component
msigdb_gocc
3,5,10,12,17,20,21,23,24,25,28,29,31,33,37,42,43,50,52,53,54,57,60,59,61,63,65,70,71,78,83,84,87,93,103,105,107,106,109,110,113,118,116,128,127,130,137,138,145,146,149,150,155,158,163,173,176,179,180,184,187,190,192,193,199,202,201,203,205,210,218,223,225,226,232,231,234,236,238,244,257,260,266,267,272,279,291,295,304,307,305,306,309,314,316,319,320,324,332,334,340,347
420,257,179,173,710,54,2385,238,1255,340,324,1307,1181,562,113,316,692,203,272,1738,1257,260,905,1426,1359,42,1487,1332,1940,2157,669,106,319,231,1488,654,1942,25,1002,116,1541,2044,832,305,670,1259,71,2045,320,1429,199,807,28,2094,1364,17,309,2020,1618,103,146,1655,1456,2401,1103,2158,31,1746,1946,314,2098,2211,1367,23,860,1162,1265,1369,107,10,218,1398,639,542,20,2072,176,736,291,137,928,127,717,697,346,389,718,2163,332,180,59,434,1499,2368,2105,2165,1817,193,1627,1109,1462,1164,759,306,659,962,1520,601,2438,865,2143,1131,789,37,1669,910,1901,307,1693,2201,677,158,24,63,1167,1845,150,2353,223,678,866,1134,2168,347,50,794,2299,190,52,1525,5,1952,210,643,138,1784,933,989,374,1345,29,745,226,61,295,145,60,568,1758,2007,532,1932,514,556,232,1064,627,608,266,163,937,43,93,869,1324,2339,485,33,775,683,83,369,2128,57,648,571,1702,105,493,1200,2387,1703,2257,2172,2359,443,155,192,234,428,21,628,1291,53,130,1350,1724,1206,12,370,685,2086,3,109,1294,1479,84,205,634,438,1445,1567,1248,497,2258,826,2040,244,855,430,78,1069,225,110,87,2090,978,267,2244,149,304,187,1301,1533,236,2059,2060,201,184,202,498,952,520,279,528,2062,1802,70,334,667,1073,118,1938,128,65,1576,1612,394
0.6592655098222254,1.132575350613476,1.5838531632440178,1.6292815636710885,0.2158976081565213,2.652792387509817,-1.381488747102993,1.2225783190817734,-0.19380576235625954,0.8478026431297777,0.8899224210436362,-0.2127003983705159,-0.15630455409864116,0.41264038385623686,2.0629782100391028,0.9177256601343565,0.23270776762766546,1.3958829972159683,1.0668374397151672,-0.48787858846125165,-0.19380576235625954,1.1195262258501388,0.06100140790540697,-0.2892607576646261,-0.2507823308904216,2.9160855263377137,-0.32814340269650955,-0.23169227715850227,-0.63348914849447,-0.8294060110663698,0.2494403407682528,2.1511554521015115,0.9038514320983293,1.260450413484564,-0.32814340269650955,0.2660959890242387,-0.63348914849447,3.152441791729436,-0.02798234723534938,2.0129711959011636,-0.3674382117784822,-0.7193072862402492,0.1133692286956227,0.9726826435647435,0.2494403407682528,-0.19380576235625954,2.4909843512906855,-0.7193072862402492,0.9038514320983293,-0.2892607576646261,1.4199477449748363,0.13065927350069947,3.1166378969590314,-0.7629618451971119,-0.2507823308904216,3.312159535019784,0.9590236072859809,-0.6976683628564239,-0.4071533609458661,2.1608111690827836,1.805183895274069,-0.42717118320069314,-0.3086510615816659,-1.5127841056693392,-0.1007594861270674,-0.8294060110663698,3.0585068888661016,-0.48787858846125165,-0.63348914849447,0.9315455033685286,-0.7629618451971119,-0.8970390410527324,-0.2507823308904216,3.236770177586504,0.09599672590438624,-0.13769618095212716,-0.19380576235625954,-0.2507823308904216,2.1511554521015115,3.48994747351802,1.3103129401771128,-0.26997150484729665,0.28267536563664253,0.4444122970173833,3.2781128849833854,-0.7410713309240917,1.6179808316611837,0.19900919256781674,1.013344258369898,1.8793700770320063,0.04337709946176049,1.9416897191826263,0.2158976081565213,0.23270776762766546,0.8336504314439626,0.7329693277559037,0.2158976081565213,-0.8294060110663698,0.8759382244797788,1.572401341063591,2.5941024654889833,0.6443398713807004,-0.32814340269650955,-1.279574662903545,-0.7629618451971119,-0.8294060110663698,-0.5289062519642656,1.4557332011052682,-0.4071533609458661,-0.1007594861270674,-0.3086510615816659,-0.13769618095212716,0.18204184259460307,0.9726826435647435,0.2660959890242387,0.00787137682826172,-0.34773878122711316,0.36445047971555095,-2.149533172513409,0.09599672590438624,-0.8071277827585696,-0.11918144832285707,0.14786758317336363,2.9692910588506276,-0.42717118320069314,0.06100140790540697,-0.5913048144722944,0.9726826435647435,-0.44729726533392017,-0.8743601688607926,0.2494403407682528,1.707357730711625,3.194884274897394,2.560087810726942,-0.13769618095212716,-0.5495903224499785,1.7944522189141074,-1.204872765188523,1.2979142914342985,0.2494403407682528,0.09599672590438624,-0.11918144832285707,-0.8294060110663698,0.8336504314439626,2.702273873382328,0.14786758317336363,-1.0360339359435122,1.4911509912268668,2.685863124657544,-0.34773878122711316,3.7597378659854743,-0.63348914849447,1.3472450660860968,0.28267536563664253,1.8688709393675171,-0.508336059704949,0.04337709946176049,-0.010011590331103102,0.7620282155096825,-0.23169227715850227,3.102203569906441,0.19900919256781674,1.2854711855638465,2.585631778102509,0.9998425933519748,1.8371768966766115,2.5941024654889833,0.41264038385623686,-0.48787858846125165,-0.6761532333776855,0.4601935811647347,-0.6123376390093992,0.4915496270065848,0.42856142165780864,1.260450413484564,-0.06419045128865337,0.31560787666756207,0.34824294069161715,1.0932809768597807,1.6852317773417498,0.04337709946176049,2.9007217131059995,2.2464793614272396,0.09599672590438624,-0.2127003983705159,-1.1558676625729167,0.5380756588239767,3.0290421086807306,0.16499487134818433,0.2494403407682528,2.3755090350781054,0.7764689191291888,-0.7849801986775056,2.610978516529192,0.28267536563664253,0.41264038385623686,-0.44729726533392017,2.1608111690827836,0.522633995537609,-0.15630455409864116,-1.381488747102993,-0.44729726533392017,-0.9659009950668074,-0.8294060110663698,-1.229612257291912,0.6293514881429343,1.7293410708596129,1.4793854803467268,1.247872145516247,0.6592655098222254,3.264391530678441,0.31560787666756207,-0.19380576235625954,2.685863124657544,1.9313825785356158,-0.23169227715850227,-0.4675326981198081,-0.15630455409864116,3.4642312200666168,0.7764689191291888,0.2494403407682528,-0.7410713309240917,4.125008978537356,2.102454677098883,-0.19380576235625954,-0.3086510615816659,2.3664570959280136,1.3958829972159683,0.2991791157749035,0.6443398713807004,-0.2892607576646261,-0.3674382117784822,-0.17500744981820085,0.5071254977386024,-0.9659009950668074,0.13065927350069947,-0.6976683628564239,1.197099367809086,0.1133692286956227,0.6592655098222254,2.4470470431650044,-0.06419045128865337,1.2979142914342985,2.092629014938214,2.357380369507811,-0.7410713309240917,0.00787137682826172,1.0932809768597807,-0.9198544438847963,1.805183895274069,0.9862888463465534,1.5262080593683736,-0.19380576235625954,-0.34773878122711316,1.2352482168259986,-0.7193072862402492,-0.7193072862402492,1.4199477449748363,1.549382379998421,1.4199477449748363,0.5071254977386024,0.02566734622848883,0.4915496270065848,1.053540441532829,0.47590583856156266,-0.7193072862402492,-0.508336059704949,2.517068436125271,0.8759382244797788,0.2660959890242387,-0.06419045128865337,2.0129711959011636,-0.6123376390093992,1.9416897191826263,2.560087810726942,-0.3674382117784822,-0.3872427236161005,0.7329693277559037
2,454
Inorganic anion transmembrane transporter activity
8
11
2.483273
0.013018
Q9C0H2,Q9Y277,P21796,P55011,Q9UBX3,P45880,O43681,Q02978
Functions
GO Molecular function
msigdb_gomf
35,170,14,337,48,22,151,281
2329,924,151,14,22,395,337,281,35,48,170
-1.1315983345381757,0.04337709946176049,1.7836865416843557,3.4383036215791014,3.2506107876916754,0.7183502411380084,0.8618984355820165,1.0401928182614306,2.9843329816197044,2.726736385136414,1.6629614855267152
2,454
Sterol biosynthetic process
8
18
2.482808
0.013035
P48449,P16435,P37268,Q9UBM7,P14324,Q14739,Q16850,Q14534
Processes and pathways
GO Biological process
msigdb_gobp
291,103,10,201,171,52,61,190
654,670,1310,171,103,10,1106,291,1969,2406,2002,190,52,374,745,61,201,952
0.2660959890242387,0.2494403407682528,-0.2127003983705159,1.6405450993859982,2.1608111690827836,3.48994747351802,-0.1007594861270674,1.013344258369898,-0.6547605908794988,-1.5395856690495455,-0.6761532333776855,1.4911509912268668,2.685863124657544,0.7620282155096825,0.19900919256781674,2.585631778102509,1.4199477449748363,0.02566734622848883
2,454
Macromolecule transmembrane transporter activity
6
12
2.482005
0.013065
O60830,Q9NS69,Q99595,O14925,Q15388,P49755
Functions
GO Molecular function
msigdb_gomf
0,1,2,165,308,346
165,0,1308,412,346,929,601,816,308,2,1,498
1.6741147827555374,4.5070088122225345,-0.2127003983705159,0.6741288888174748,0.8336504314439626,0.04337709946176049,0.36445047971555095,0.13065927350069947,0.9726826435647435,4.326911646644879,4.336663022143436,0.5071254977386024
2,454
Metal ion transmembrane transporter activity
10
19
2.48113
0.013097
Q8N4V1,Q9HD20,Q9H2J7,P55011,Q6P4Q7,P16615,Q9UM00,P20020,O95202,P05023
Functions
GO Molecular function
msigdb_gomf
33,78,143,337,366,146,279,247,157,217
157,217,563,1811,1684,607,146,247,388,337,601,1670,366,33,723,2258,143,78,279
1.707357730711625,1.3103129401771128,0.41264038385623686,-0.5289062519642656,-0.44729726533392017,0.34824294069161715,1.805183895274069,1.1714327633031296,0.7329693277559037,0.8618984355820165,0.36445047971555095,-0.42717118320069314,0.7764689191291888,3.0290421086807306,0.2158976081565213,-0.9659009950668074,1.8477745387244804,2.4470470431650044,1.053540441532829
2,454
Endoplasmic reticulum organization
13
36
2.478695
0.013186
P49069,Q8N4V1,Q96A33,P57088,Q9NPA0,Q15041,Q9P2W9,P46379,Q00765,Q9NQC3,O43681,O95197,Q15629
Processes and pathways
GO Biological process
msigdb_gobp
127,33,155,193,225,138,236,81,307,87,151,25,29
420,710,2134,1181,151,1836,1942,25,1002,81,127,717,193,306,601,307,866,643,138,1784,29,568,1758,1287,33,683,369,155,1479,2040,1069,225,87,2244,1301,236
0.6592655098222254,0.2158976081565213,-0.8071277827585696,-0.15630455409864116,1.7836865416843557,-0.5495903224499785,-0.63348914849447,3.152441791729436,-0.02798234723534938,2.393539051580102,1.9416897191826263,0.2158976081565213,1.4557332011052682,0.9726826435647435,0.36445047971555095,0.9726826435647435,0.09599672590438624,0.28267536563664253,1.8688709393675171,-0.508336059704949,3.102203569906441,0.41264038385623686,-0.48787858846125165,-0.19380576235625954,3.0290421086807306,0.2494403407682528,0.7764689191291888,1.7293410708596129,-0.3086510615816659,-0.6976683628564239,-0.06419045128865337,1.2979142914342985,2.357380369507811,-0.9198544438847963,-0.19380576235625954,1.2352482168259986
2,454
Electron transport chain oxphos system in mitochondria
22
40
2.475439
0.013307
O00483,O75880,O95168,P00403,P21912,Q9UDW1,P06576,P14406,O43676,Q9Y6M9,P05141,O75964,P22695,P12235,P12236,O14949,P20674,P24539,P56385,O75306,P56134,P13073
Processes and pathways
WikiPathways
msigdb_wp
500,387,503,263,397,19,529,26,27,419,285,40,294,299,175,55,440,80,475,356,363,115
500,55,27,693,356,1769,387,551,40,503,1360,263,285,529,1616,766,299,175,115,26,732,1776,440,397,294,80,1104,2159,1458,656,754,2181,2162,363,475,1137,845,19,953,419
0.4915496270065848,2.652792387509817,3.123830761702728,0.23270776762766546,0.8051750649785682,-0.508336059704949,0.7329693277559037,0.42856142165780864,2.938995264788679,0.4915496270065848,-0.2507823308904216,1.0932809768597807,1.026794211311183,0.4601935811647347,-0.4071533609458661,0.16499487134818433,0.9862888463465534,1.6179808316611837,2.0230322589366674,3.1310075169748237,0.19900919256781674,-0.508336059704949,0.6293514881429343,0.7036707826264457,0.9998425933519748,2.4025173766417525,-0.1007594861270674,-0.8294060110663698,-0.3086510615816659,0.2660959890242387,0.18204184259460307,-0.851816319929439,-0.8294060110663698,0.7764689191291888,0.5534510197557548,-0.11918144832285707,0.1133692286956227,3.3053793135556817,0.02566734622848883,0.6741288888174748
2,454
Organic acid transport
17
33
2.469976
0.013512
O60831,P23786,Q9H2D1,Q9UJS0,O43808,Q15041,Q9H2J7,Q9UBX3,P55011,P31751,O43772,P28288,P53985,Q9Y619,Q02978,P08183,O75915
Processes and pathways
GO Biological process
msigdb_gobp
121,197,6,250,168,138,143,48,337,402,114,277,214,350,281,90,319
2263,924,114,168,121,423,319,832,1810,2366,671,1965,90,607,620,197,277,402,1265,508,214,337,281,138,1784,664,627,6,143,1449,48,250,350
-0.9891352838762909,0.04337709946176049,2.0230322589366674,1.6629614855267152,1.972423639877387,0.6592655098222254,0.9038514320983293,0.1133692286956227,-0.5289062519642656,-1.279574662903545,0.2494403407682528,-0.6547605908794988,2.2838588768570314,0.34824294069161715,0.31560787666756207,1.4319175188017423,1.053540441532829,0.6889304882517738,-0.19380576235625954,0.4915496270065848,1.3349780380688931,0.8618984355820165,1.0401928182614306,1.8688709393675171,-0.508336059704949,0.2660959890242387,0.31560787666756207,3.6277474447573046,1.8477745387244804,-0.2892607576646261,2.726736385136414,1.1714327633031296,0.8336504314439626
2,454
Calcium signaling pathway
8
14
2.468716
0.01356
P05141,Q9Y277,P12235,P21796,P12236,P16615,P45880,P20020
Processes and pathways
KEGG Pathways
msigdb_kegg
285,170,299,14,175,146,22,247
285,299,175,146,886,247,14,388,22,2166,1134,2168,1421,170
1.026794211311183,0.9862888463465534,1.6179808316611837,1.805183895274069,0.07854103289676595,1.1714327633031296,3.4383036215791014,0.7329693277559037,3.2506107876916754,-0.8294060110663698,-0.11918144832285707,-0.8294060110663698,-0.26997150484729665,1.6629614855267152
2,454
Regulation of blood pressure
7
15
2.463654
0.013753
Q9HB40,P42785,P42892,Q9UIQ6,P09601,P20020,P05023
Processes and pathways
GO Biological process
msigdb_gobp
164,73,77,241,17,247,217
2093,217,17,2324,247,73,77,1163,1749,1520,771,1064,164,304,241
-0.7629618451971119,1.3103129401771128,3.312159535019784,-1.1074820632844848,1.1714327633031296,2.464692228627964,2.4470470431650044,-0.13769618095212716,-0.48787858846125165,-0.34773878122711316,0.16499487134818433,-0.06419045128865337,1.6852317773417498,0.9862888463465534,1.2098621409006676
2,454
Secondary alcohol metabolic process
12
33
2.461373
0.013841
Q9BQE5,Q14849,O15118,P05067,P04062,P16435,P37268,P14324,Q8WTV0,Q14739,Q16850,Q14534
Processes and pathways
GO Biological process
msigdb_gobp
3,5,102,199,71,103,10,171,46,52,61,190
102,958,2313,654,670,71,199,1310,171,103,10,1106,291,2423,1082,2073,578,1969,317,2001,2406,2002,190,52,5,374,745,61,46,1936,3,201,392
2.1608111690827836,0.00787137682826172,-1.0835170684061923,0.2660959890242387,0.2494403407682528,2.4909843512906855,1.4199477449748363,-0.2127003983705159,1.6405450993859982,2.1608111690827836,3.48994747351802,-0.1007594861270674,1.013344258369898,-1.7894811458568527,-0.08242943604018182,-0.7410713309240917,0.3966486055076561,-0.6547605908794988,0.9177256601343565,-0.6761532333776855,-1.5395856690495455,-0.6761532333776855,1.4911509912268668,2.685863124657544,3.7597378659854743,0.7620282155096825,0.19900919256781674,2.585631778102509,2.7751176885302846,-0.6123376390093992,4.125008978537356,1.4199477449748363,0.7329693277559037
2,454
Cholesterol metabolism
9
16
2.457959
0.013973
O15118,P04062,P37268,Q9UBM7,P14324,Q14739,Q15392,Q16850,P61916
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
102,71,10,201,171,52,374,61,317
102,654,670,71,171,10,317,2001,2406,2002,52,374,745,61,201,392
2.1608111690827836,0.2660959890242387,0.2494403407682528,2.4909843512906855,1.6405450993859982,3.48994747351802,0.9177256601343565,-0.6761532333776855,-1.5395856690495455,-0.6761532333776855,2.685863124657544,0.7620282155096825,0.19900919256781674,2.585631778102509,1.4199477449748363,0.7329693277559037
2,454
Nuclear inner membrane
10
16
2.451778
0.014215
P50402,O75844,Q9BTV4,Q99720,Q9H1E5,Q9Y2U8,Q14739,Q03252,Q5SNT2,P20700
Localization
GO Cellular component
msigdb_gocc
389,106,526,12,111,534,52,510,186,345
106,345,1967,838,389,1818,544,510,1168,52,645,186,12,526,111,534
2.1511554521015115,0.8336504314439626,-0.6547605908794988,0.1133692286956227,0.7329693277559037,-0.5289062519642656,0.4444122970173833,0.4915496270065848,-0.13769618095212716,2.685863124657544,0.28267536563664253,1.5262080593683736,3.4642312200666168,0.47590583856156266,2.0728909396765256,0.4601935811647347
2,454
Metabolism of lipids
41
126
2.450482
0.014267
Q96N66,Q14849,P09960,P48651,P37268,Q15165,Q9NTJ5,P16278,Q53GQ0,P17900,Q9H7Z7,Q96G23,Q9NZ01,O43681,Q06136,Q9NPH0,P50897,P48449,O43808,P14324,Q13510,O95864,Q14739,Q9UG56,Q9P035,P51648,Q16850,Q14534,Q9NZJ7,O00116,P23786,P04062,Q9UBM7,Q8NF37,Q8IV08,P38435,Q10713,Q8N8N7,O00767,O43772,O95470
Processes and pathways
Reactome Pathways
msigdb_reactome
130,5,133,137,10,11,267,142,145,144,148,21,149,151,24,159,32,291,168,171,45,305,52,312,187,59,61,190,195,196,197,71,201,83,93,218,223,230,238,114,116
420,196,1254,2435,238,1255,362,316,151,114,168,1426,784,2208,1807,1002,116,1541,2044,832,305,71,2447,1773,552,713,638,133,454,2444,171,1743,2443,655,142,886,144,809,1103,1057,197,1338,2265,1265,507,1814,10,218,483,1106,613,553,291,137,928,1546,1082,32,59,413,1969,2165,1690,659,1666,931,889,2406,24,223,2452,45,2002,190,52,5,490,1952,582,11,406,374,1345,745,681,61,1195,1595,145,426,1171,93,2339,230,83,517,2373,21,130,1825,1378,2085,467,825,2036,685,1479,1566,1447,1248,148,159,1383,267,2244,149,195,187,1301,2060,201,312,1302,1155,378,956
0.6592655098222254,1.4319175188017423,-0.19380576235625954,-2.0258318051816477,1.2225783190817734,-0.19380576235625954,0.7764689191291888,0.9177256601343565,1.7836865416843557,2.0230322589366674,1.6629614855267152,-0.2892607576646261,0.14786758317336363,-0.8970390410527324,-0.5289062519642656,-0.02798234723534938,2.0129711959011636,-0.3674382117784822,-0.7193072862402492,0.1133692286956227,0.9726826435647435,2.4909843512906855,-3.3479781746602133,-0.508336059704949,0.42856142165780864,0.2158976081565213,0.28267536563664253,1.9002711628395195,0.5840049324470407,-2.722727992482984,1.6405450993859982,-0.48787858846125165,-2.650898939550229,0.2660959890242387,1.8583391561768707,0.07854103289676595,1.8371768966766115,0.13065927350069947,-0.1007594861270674,-0.06419045128865337,1.4319175188017423,-0.23169227715850227,-0.9891352838762909,-0.19380576235625954,0.4915496270065848,-0.5289062519642656,3.48994747351802,1.3103129401771128,0.5380756588239767,-0.1007594861270674,0.33196227773033055,0.42856142165780864,1.013344258369898,1.8793700770320063,0.04337709946176049,-0.3674382117784822,-0.08242943604018182,3.0364336472060622,2.5941024654889833,0.6741288888174748,-0.6547605908794988,-0.8294060110663698,-0.44729726533392017,0.2660959890242387,-0.42717118320069314,0.04337709946176049,0.07854103289676595,-1.5395856690495455,3.194884274897394,1.2979142914342985,-4.84595143444432,2.8227904319852435,-0.6761532333776855,1.4911509912268668,2.685863124657544,3.7597378659854743,0.522633995537609,-0.63348914849447,0.3966486055076561,3.4706799718977637,0.6889304882517738,0.7620282155096825,-0.23169227715850227,0.19900919256781674,0.2494403407682528,2.585631778102509,-0.15630455409864116,-0.3872427236161005,1.8371768966766115,0.6592655098222254,-0.13769618095212716,2.2464793614272396,-1.1558676625729167,1.2729833260513288,2.3755090350781054,0.4915496270065848,-1.3048014939574935,3.264391530678441,1.9313825785356158,-0.5289062519642656,-0.2507823308904216,-0.7410713309240917,0.5687606043241162,0.13065927350069947,-0.6976683628564239,0.2494403407682528,-0.3086510615816659,-0.3674382117784822,-0.2892607576646261,-0.17500744981820085,1.805183895274069,1.696312687795655,-0.2507823308904216,1.0932809768597807,-0.9198544438847963,1.805183895274069,1.4557332011052682,1.5262080593683736,-0.19380576235625954,-0.7193072862402492,1.4199477449748363,0.9453113558034467,-0.19380576235625954,-0.11918144832285707,0.7620282155096825,0.02566734622848883
2,454
Cristae formation
12
18
2.448041
0.014364
Q13505,O75964,Q16891,Q9BUR5,Q5XKP0,Q9NX63,O75431,P24539,P56134,P06576,P56385,Q9Y512
Processes and pathways
Reactome Pathways
msigdb_reactome
97,40,491,205,240,303,422,80,363,529,475,284
422,551,40,529,80,1104,754,2212,2181,363,475,97,491,240,205,1017,303,284
0.6592655098222254,0.42856142165780864,2.938995264788679,0.4601935811647347,2.4025173766417525,-0.1007594861270674,0.18204184259460307,-0.8970390410527324,-0.851816319929439,0.7764689191291888,0.5534510197557548,2.1991575594968427,0.522633995537609,1.2225783190817734,1.3958829972159683,-0.02798234723534938,0.9862888463465534,1.0401928182614306
2,454
Steroid metabolism
9
18
2.437631
0.014784
O15118,P04062,P37268,Q9UBM7,P14324,Q14739,Q15392,Q16850,P61916
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
102,71,10,201,171,52,374,61,317
102,654,670,71,171,10,317,2001,2406,2002,52,374,745,61,2013,201,392,952
2.1608111690827836,0.2660959890242387,0.2494403407682528,2.4909843512906855,1.6405450993859982,3.48994747351802,0.9177256601343565,-0.6761532333776855,-1.5395856690495455,-0.6761532333776855,2.685863124657544,0.7620282155096825,0.19900919256781674,2.585631778102509,-0.6761532333776855,1.4199477449748363,0.7329693277559037,0.02566734622848883
2,454
Microbody membrane
10
17
2.429279
0.015129
P51659,O00116,O43808,Q8NBU5,O75381,Q9NR77,O15228,P28288,Q8WVX9,P51648
Localization
GO Cellular component
msigdb_gocc
413,196,168,557,335,49,362,277,517,59
196,362,168,1426,335,832,1920,277,1265,59,413,582,557,517,1207,1447,49
1.4319175188017423,0.7764689191291888,1.6629614855267152,-0.2892607576646261,0.8618984355820165,0.1133692286956227,-0.6123376390093992,1.053540441532829,-0.19380576235625954,2.5941024654889833,0.6741288888174748,0.3966486055076561,0.42856142165780864,0.4915496270065848,-0.15630455409864116,-0.2892607576646261,2.7104484304643575
2,454
Organic acid transmembrane transporter activity
8
16
2.428717
0.015152
Q9H2D1,Q02978,Q9H2J7,Q9UBX3,P53985,Q9Y619,Q9UJS0,P08183
Functions
GO Molecular function
msigdb_gomf
6,281,143,48,214,350,250,90
2263,924,423,90,607,508,214,281,664,627,6,143,1449,48,250,350
-0.9891352838762909,0.04337709946176049,0.6592655098222254,2.2838588768570314,0.34824294069161715,0.4915496270065848,1.3349780380688931,1.0401928182614306,0.2660959890242387,0.31560787666756207,3.6277474447573046,1.8477745387244804,-0.2892607576646261,2.726736385136414,1.1714327633031296,0.8336504314439626
2,454
Dicarboxylic acid transport
8
13
2.42389
0.015355
Q9UJS0,Q9H2D1,Q02978,Q15041,P55011,Q9UBX3,O60831,O75915
Processes and pathways
GO Biological process
msigdb_gobp
250,6,281,138,337,48,121,319
121,423,319,671,508,337,281,138,1784,664,6,48,250
1.972423639877387,0.6592655098222254,0.9038514320983293,0.2494403407682528,0.4915496270065848,0.8618984355820165,1.0401928182614306,1.8688709393675171,-0.508336059704949,0.2660959890242387,3.6277474447573046,2.726736385136414,1.1714327633031296
2,454
Receptor
8
20
2.419119
0.015558
Q9UQB8,Q9HCD5,Q567V2,A6NIH7,Q8WTV0,Q9NR77,Q14108,Q9BUN8
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
256,322,7,44,46,49,50,84
44,982,1738,335,2136,1579,671,2020,50,7,46,1934,84,1354,322,49,2319,781,256,447
2.838527195199176,-0.010011590331103102,-0.48787858846125165,0.8618984355820165,-0.8071277827585696,-0.3872427236161005,0.2494403407682528,-0.6976683628564239,2.702273873382328,3.5783352045461188,2.7751176885302846,-0.6123376390093992,2.3664570959280136,-0.23169227715850227,0.9038514320983293,2.7104484304643575,-1.0835170684061923,0.16499487134818433,1.1455759264064622,0.6293514881429343
2,454
Active ion transmembrane transporter activity
24
33
2.414891
0.01574
P23634,P00403,P41440,P51790,Q9H2J7,P16615,Q9UDW1,P06576,Q02978,O95202,P05141,P12235,O00400,P12236,P05026,P20674,P08574,Q9HD20,P55011,P05023,P08195,Q00325,P13073,P20020
Functions
GO Molecular function
msigdb_gomf
388,263,508,395,143,146,19,529,281,157,285,299,173,175,563,440,576,78,337,217,607,616,115,247
173,924,157,263,217,563,285,529,607,576,766,299,175,115,146,247,440,2295,2325,388,656,1685,2023,508,395,337,614,616,281,143,78,19,1385
1.6292815636710885,0.04337709946176049,1.707357730711625,1.0932809768597807,1.3103129401771128,0.41264038385623686,1.026794211311183,0.4601935811647347,0.34824294069161715,0.3966486055076561,0.16499487134818433,0.9862888463465534,1.6179808316611837,2.0230322589366674,1.805183895274069,1.1714327633031296,0.6293514881429343,-1.0360339359435122,-1.1074820632844848,0.7329693277559037,0.2660959890242387,-0.44729726533392017,-0.6976683628564239,0.4915496270065848,0.7183502411380084,0.8618984355820165,0.33196227773033055,0.33196227773033055,1.0401928182614306,1.8477745387244804,2.4470470431650044,3.3053793135556817,-0.2507823308904216
2,454
Carboxylic acid transport
12
25
2.412839
0.015829
Q9NZJ7,O60831,Q9UJS0,Q9H2D1,Q15041,Q9H2J7,Q9UBX3,P55011,P28288,P53985,Q02978,O75915
Processes and pathways
GO Biological process
msigdb_gobp
195,121,250,6,138,143,48,337,277,214,281,319
2263,924,121,423,319,2366,671,607,620,277,508,214,337,281,138,1784,664,627,6,143,1449,195,48,250,350
-0.9891352838762909,0.04337709946176049,1.972423639877387,0.6592655098222254,0.9038514320983293,-1.279574662903545,0.2494403407682528,0.34824294069161715,0.31560787666756207,1.053540441532829,0.4915496270065848,1.3349780380688931,0.8618984355820165,1.0401928182614306,1.8688709393675171,-0.508336059704949,0.2660959890242387,0.31560787666756207,3.6277474447573046,1.8477745387244804,-0.2892607576646261,1.4557332011052682,2.726736385136414,1.1714327633031296,0.8336504314439626
2,454
Vacuolar membrane
22
92
2.412803
0.01583
P11117,Q14849,P11279,Q9Y487,Q92542,O15400,Q93050,Q8WTV0,Q14108,P10253,Q07065,Q9NZJ7,P04062,P42785,P42892,Q8NF37,Q8IV08,O15118,Q9UIQ6,Q86YV9,O75503,O75955
Localization
GO Cellular component
msigdb_gocc
129,5,262,13,147,280,36,46,50,182,63,195,71,73,77,83,93,102,241,242,122,126
2155,1049,102,280,1738,1223,2272,2208,122,126,2136,521,1579,71,1429,1811,1684,607,1489,1364,182,454,129,1812,262,2295,2325,2158,1660,1459,1685,2023,1398,508,542,73,77,2072,864,738,395,434,759,659,614,1589,1901,1466,63,2167,2353,50,5,680,847,242,93,286,83,46,1794,2387,147,36,547,918,971,824,1350,467,1206,2242,2036,2445,1567,497,518,2258,650,1212,195,1301,1044,1385,241,1801,528,955,1831,690,479,13
-0.8294060110663698,-0.06419045128865337,2.1608111690827836,1.0401928182614306,-0.48787858846125165,-0.17500744981820085,-1.0125123853599192,-0.8970390410527324,1.9622100740129906,1.9416897191826263,-0.8071277827585696,0.47590583856156266,-0.3872427236161005,2.4909843512906855,-0.2892607576646261,-0.5289062519642656,-0.44729726533392017,0.34824294069161715,-0.32814340269650955,-0.2507823308904216,1.5609111596332113,0.5840049324470407,1.9313825785356158,-0.5289062519642656,1.1064282148367273,-1.0360339359435122,-1.1074820632844848,-0.8294060110663698,-0.42717118320069314,-0.3086510615816659,-0.44729726533392017,-0.6976683628564239,-0.26997150484729665,0.4915496270065848,0.4444122970173833,2.464692228627964,2.4470470431650044,-0.7410713309240917,0.09599672590438624,0.19900919256781674,0.7183502411380084,0.6443398713807004,0.18204184259460307,0.2660959890242387,0.33196227773033055,-0.3872427236161005,-0.5913048144722944,-0.3086510615816659,2.560087810726942,-0.8294060110663698,-1.204872765188523,2.702273873382328,3.7597378659854743,0.2494403407682528,0.1133692286956227,1.197099367809086,2.2464793614272396,1.026794211311183,2.3755090350781054,2.7751176885302846,-0.508336059704949,-1.381488747102993,1.805183895274069,2.9768207877432644,0.4444122970173833,0.06100140790540697,0.00787137682826172,0.13065927350069947,-0.23169227715850227,0.5687606043241162,-0.15630455409864116,-0.9198544438847963,-0.6976683628564239,-2.722727992482984,-0.3674382117784822,0.5071254977386024,0.4915496270065848,-0.9659009950668074,0.28267536563664253,-0.15630455409864116,1.4557332011052682,-0.19380576235625954,-0.04604169644634782,-0.2507823308904216,1.2098621409006676,-0.508336059704949,0.47590583856156266,0.02566734622848883,-0.5289062519642656,0.2494403407682528,0.5534510197557548,3.45129403999315
2,454
Hydrolase activity hydrolyzing o glycosyl compounds
7
18
2.410788
0.015918
P04062,P16278,Q9BTY2,P17900,P10253,Q9NUJ1,P54802
Functions
GO Molecular function
msigdb_gomf
71,142,338,144,182,183,248
830,71,552,713,638,833,182,142,144,735,248,347,1243,949,467,338,183,2312
0.1133692286956227,2.4909843512906855,0.42856142165780864,0.2158976081565213,0.28267536563664253,0.1133692286956227,1.5609111596332113,1.8583391561768707,1.8371768966766115,0.19900919256781674,1.1714327633031296,0.8336504314439626,-0.17500744981820085,0.02566734622848883,0.5687606043241162,0.8618984355820165,1.549382379998421,-1.059701599588804
2,454
Protein transmembrane transporter activity
6
11
2.409052
0.015994
O60830,Q9NS69,Q99595,O14925,Q15388,P49755
Functions
GO Molecular function
msigdb_gomf
0,1,2,165,308,346
165,0,1308,412,346,601,816,308,2,1,498
1.6741147827555374,4.5070088122225345,-0.2127003983705159,0.6741288888174748,0.8336504314439626,0.36445047971555095,0.13065927350069947,0.9726826435647435,4.326911646644879,4.336663022143436,0.5071254977386024
2,454
Respirasome
17
32
2.398673
0.016455
O00483,O75306,P20674,P00403,P22695,Q13423,Q86Y39,P21912,Q9UDW1,Q9Y375,P13073,O14949,P14406,O43676,Q9NX14,Q9Y6M9,Q6DKK2
Localization
GO Cellular component
msigdb_gocc
500,356,440,263,294,72,249,397,19,343,115,55,26,27,384,419,255
500,55,27,693,356,1769,503,1360,263,576,1616,766,115,26,732,1776,440,397,294,2159,1458,656,2162,72,1137,845,255,249,384,19,343,419
0.4915496270065848,2.652792387509817,3.123830761702728,0.23270776762766546,0.8051750649785682,-0.508336059704949,0.4915496270065848,-0.2507823308904216,1.0932809768597807,0.3966486055076561,-0.4071533609458661,0.16499487134818433,2.0230322589366674,3.1310075169748237,0.19900919256781674,-0.508336059704949,0.6293514881429343,0.7036707826264457,0.9998425933519748,-0.8294060110663698,-0.3086510615816659,0.2660959890242387,-0.8294060110663698,2.4909843512906855,-0.11918144832285707,0.1133692286956227,1.1455759264064622,1.1714327633031296,0.7475285012988273,3.3053793135556817,0.8478026431297777,0.6741288888174748
2,454
transfer/carrier protein
6
10
2.393572
0.016685
P05141,Q9Y5M8,P12235,P12236,O15127,P17900
Functions
Panther Protein class
panther_protein_class
285,65,299,175,113,144
340,562,113,1807,285,299,175,144,1057,65
0.8478026431297777,0.41264038385623686,2.0629782100391028,-0.5289062519642656,1.026794211311183,0.9862888463465534,1.6179808316611837,1.8371768966766115,-0.06419045128865337,2.560087810726942
2,454
Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins
27
52
2.37074
0.017753
O00483,O75880,O95168,P00403,Q8IUX1,P21912,Q9UDW1,P06576,O43676,Q9Y6M9,O75964,P22695,O75947,O14949,Q9NPL8,P20674,Q9BQ95,Q9P032,P24539,Q9Y375,Q16134,P56385,O75306,P56134,P13073,Q86Y39,Q9NX14
Processes and pathways
Reactome Pathways
msigdb_reactome
500,387,503,263,140,397,19,529,27,419,40,294,551,55,188,440,585,468,80,343,216,475,356,363,115,249,384
500,55,27,693,356,1769,387,551,40,503,1360,263,529,576,1616,766,115,1861,732,1776,440,397,294,80,1104,2159,1458,656,754,1661,1967,2181,2162,363,475,1467,216,1137,845,1437,249,140,647,585,1208,1040,188,384,468,19,343,419
0.4915496270065848,2.652792387509817,3.123830761702728,0.23270776762766546,0.8051750649785682,-0.508336059704949,0.7329693277559037,0.42856142165780864,2.938995264788679,0.4915496270065848,-0.2507823308904216,1.0932809768597807,0.4601935811647347,0.3966486055076561,-0.4071533609458661,0.16499487134818433,2.0230322589366674,-0.5703894458091343,0.19900919256781674,-0.508336059704949,0.6293514881429343,0.7036707826264457,0.9998425933519748,2.4025173766417525,-0.1007594861270674,-0.8294060110663698,-0.3086510615816659,0.2660959890242387,0.18204184259460307,-0.42717118320069314,-0.6547605908794988,-0.851816319929439,-0.8294060110663698,0.7764689191291888,0.5534510197557548,-0.3086510615816659,1.3226674254457509,-0.11918144832285707,0.1133692286956227,-0.2892607576646261,1.1714327633031296,1.8688709393675171,0.28267536563664253,0.3966486055076561,-0.15630455409864116,-0.04604169644634782,1.5145620294556341,0.7475285012988273,0.5687606043241162,3.3053793135556817,0.8478026431297777,0.6741288888174748
2,454
Alcohol metabolic process
21
62
2.366245
0.01797
Q9BQE5,Q14849,P37268,P48449,P05091,P14324,Q13510,Q8WTV0,Q14739,Q8NBN7,P51648,O15269,Q14534,Q16850,P61916,P05067,P04062,Q9UBM7,Q10713,O15118,P16435
Processes and pathways
GO Biological process
msigdb_gobp
3,5,10,291,298,171,45,46,52,185,59,316,190,61,317,199,71,201,223,102,103
2413,102,316,1452,958,1487,2313,1226,654,336,670,71,199,298,1310,2324,171,2066,1743,103,1862,945,2425,10,1106,613,291,2423,1082,2073,578,1999,1749,59,1969,2336,317,2001,2406,223,45,2002,190,52,5,374,745,61,514,185,648,46,2269,1936,3,591,1447,1507,201,392,1573,667
-1.5937499890522795,2.1608111690827836,0.9177256601343565,-0.3086510615816659,0.00787137682826172,-0.32814340269650955,-1.0835170684061923,-0.17500744981820085,0.2660959890242387,0.8618984355820165,0.2494403407682528,2.4909843512906855,1.4199477449748363,0.9862888463465534,-0.2127003983705159,-1.1074820632844848,1.6405450993859982,-0.7410713309240917,-0.48787858846125165,2.1608111690827836,-0.5703894458091343,0.02566734622848883,-1.8182597407279888,3.48994747351802,-0.1007594861270674,0.33196227773033055,1.013344258369898,-1.7894811458568527,-0.08242943604018182,-0.7410713309240917,0.3966486055076561,-0.6761532333776855,-0.48787858846125165,2.5941024654889833,-0.6547605908794988,-1.1558676625729167,0.9177256601343565,-0.6761532333776855,-1.5395856690495455,1.2979142914342985,2.8227904319852435,-0.6761532333776855,1.4911509912268668,2.685863124657544,3.7597378659854743,0.7620282155096825,0.19900919256781674,2.585631778102509,0.4915496270065848,1.5378147610241326,0.28267536563664253,2.7751176885302846,-0.9891352838762909,-0.6123376390093992,4.125008978537356,0.3805855015225713,-0.2892607576646261,-0.32814340269650955,1.4199477449748363,0.7329693277559037,-0.3674382117784822,0.2660959890242387
2,454
Endoplasmic reticulum
134
376
2.348051
0.018872
Q9BQE5,Q14849,P37268,Q99720,P09601,P43307,Q96G23,P30519,Q06136,O95197,P07099,Q15629,P24390,Q8N4V1,Q9H6V9,P67812,O15173,O60725,Q86XL3,Q13510,Q14108,Q14739,Q96KC8,Q8TB61,Q5BJF2,P51648,Q16850,Q07065,Q9Y5M8,Q9Y282,P04062,Q9HD20,Q8NF37,Q9BUN8,Q9NQC3,Q8IV08,O15118,P16435,Q8TCT9,P35613,O75844,P80303,Q9BRR6,Q9Y3B3,O95470,Q9NWM8,O75503,Q02818,Q9Y4P3,P49069,Q96N66,Q5W0Z9,P48651,Q15041,Q53GQ0,P16615,Q92542,Q9NZ01,Q10472,O43681,P62847,Q96A33,Q9UMX5,Q03519,Q86UE4,Q14257,O00400,P46977,Q9Y680,O00264,P51572,Q9UBU6,Q9P035,Q14534,Q96A57,P57088,P05067,Q9UBV2,Q9UBM7,O43292,Q9BUR5,Q99797,Q15005,Q01105,P38435,P05023,Q9NPA0,Q15904,Q6NUQ4,O76024,O15258,Q96AG4,Q9P2W9,O00767,Q86YV9,Q9H3N1,Q92791,P48723,Q9UQB8,A1L0T0,Q9NR31,O43852,Q70UQ0,Q9NTJ5,O43464,Q15631,Q9UM00,Q8IY95,O95433,P48449,O00165,Q9NZ08,Q00765,O95864,P61026,P10321,O00584,P27824,O15269,P61916,O75915,P04843,Q6ZXV5,O14880,P51571,Q9Y320,Q9BTY2,P62820,Q13724,P49755,P55327,Q99735,Q8NHH9,P83881
Localization
GO Cellular component
msigdb_gocc
3,5,10,12,17,20,21,23,24,25,28,29,31,33,34,37,39,42,43,45,50,52,53,57,60,59,61,63,65,70,71,78,83,84,87,93,102,103,105,107,106,108,109,118,116,117,122,124,128,127,130,134,137,138,145,146,147,149,150,151,152,155,156,158,163,169,173,176,178,179,180,184,187,190,192,193,199,202,201,203,205,211,210,215,218,217,225,226,232,231,233,234,236,238,242,244,253,254,256,257,261,260,266,267,272,278,279,286,290,291,297,304,307,305,306,309,313,314,316,317,319,320,327,324,332,334,338,341,347,346,358,370,369,364
420,257,297,179,173,710,2385,313,238,1255,324,1307,1181,102,39,233,316,2332,574,1122,692,203,595,272,151,260,905,1426,439,1359,42,1487,1332,2157,669,122,1124,550,106,319,231,2117,1488,654,1942,25,1002,290,597,116,1541,2044,832,1390,305,749,1428,670,1259,71,2045,1003,320,1429,217,199,2230,807,28,504,2094,1364,17,1391,309,454,1860,1653,768,2192,1944,1618,103,146,2376,1655,1456,2417,1056,1103,1057,2158,2069,733,31,1311,734,1365,1746,471,1621,1946,314,2211,1366,753,1367,23,810,860,1162,1265,735,1369,107,599,10,218,1398,542,2198,20,839,1268,657,176,736,291,137,254,928,127,757,717,697,346,389,1058,1517,332,180,59,434,1499,1129,2368,2105,2165,1817,1690,358,193,1627,1109,1164,1663,759,306,659,1665,962,1520,601,2438,317,865,813,414,1317,341,152,2143,1131,1668,789,37,760,108,615,364,910,307,215,2107,1693,124,814,2201,677,158,24,912,741,63,1845,150,678,1241,866,1275,1242,842,404,45,1134,2168,347,50,1718,794,169,2299,190,1243,52,5,1952,210,643,138,1784,2077,933,1032,989,374,934,1345,29,278,948,745,226,61,1374,145,60,568,1758,532,1932,134,514,556,232,1064,627,608,2170,327,266,1821,163,937,43,242,1197,93,1324,798,2339,286,485,33,775,683,1090,1603,83,369,2128,57,648,571,1702,105,516,493,1934,1200,1703,147,2012,253,2172,2359,443,155,192,234,2149,428,21,628,1291,53,130,1350,1724,2083,2269,1206,12,370,211,685,3,573,109,1294,1479,526,338,84,205,634,438,1248,2258,826,874,2040,244,1382,34,855,430,78,1069,225,87,261,978,267,993,117,2244,1800,149,304,187,1301,1533,1356,236,2059,2060,201,184,202,2361,498,1481,1421,952,279,156,1482,528,2062,1573,256,1302,70,981,334,667,118,1938,1220,128,65,1612,394,178,637
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2,454
Abnormality of the mitochondrion
30
77
2.347175
0.018916
O75880,P00403,Q8IUX1,P21912,Q9Y2R0,Q13501,Q9H0R6,Q70HW3,O43676,Q9Y6M9,Q4J6C6,P12235,Q9UBX3,Q9NPL8,P20674,P23786,P09622,Q9P032,O00330,Q9Y375,Q16134,O75306,P40939,O75648,O43772,P13073,P35637,Q86Y39,Q3ZCQ8,Q9NX14
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
387,263,140,397,18,404,415,153,27,419,295,299,48,188,440,197,325,468,339,343,216,356,483,480,114,115,373,249,512,384
339,710,500,27,114,693,356,1769,480,387,1360,263,885,325,2095,1335,2444,299,115,1861,1776,440,397,197,1997,2159,2265,1458,373,1814,1661,483,1967,1623,1082,2162,1548,1026,908,1817,790,616,1089,404,2003,216,845,681,1786,512,1787,295,1721,153,797,1822,249,140,647,1702,2224,919,992,2013,1208,415,1040,188,384,468,1645,48,18,343,1177,1045,419
0.8478026431297777,0.2158976081565213,0.4915496270065848,3.123830761702728,2.0230322589366674,0.23270776762766546,0.8051750649785682,-0.508336059704949,0.5380756588239767,0.7329693277559037,-0.2507823308904216,1.0932809768597807,0.07854103289676595,0.8899224210436362,-0.7629618451971119,-0.23169227715850227,-2.722727992482984,0.9862888463465534,2.0230322589366674,-0.5703894458091343,-0.508336059704949,0.6293514881429343,0.7036707826264457,1.4319175188017423,-0.6761532333776855,-0.8294060110663698,-0.9891352838762909,-0.3086510615816659,0.7620282155096825,-0.5289062519642656,-0.42717118320069314,0.5380756588239767,-0.6547605908794988,-0.4071533609458661,-0.08242943604018182,-0.8294060110663698,-0.3674382117784822,-0.04604169644634782,0.06100140790540697,-0.5289062519642656,0.14786758317336363,0.33196227773033055,-0.08242943604018182,0.6889304882517738,-0.6761532333776855,1.3226674254457509,0.1133692286956227,0.2494403407682528,-0.508336059704949,0.4915496270065848,-0.508336059704949,0.9998425933519748,-0.4675326981198081,1.7293410708596129,0.14786758317336363,-0.5289062519642656,1.1714327633031296,1.8688709393675171,0.28267536563664253,-0.44729726533392017,-0.8970390410527324,0.06100140790540697,-0.010011590331103102,-0.6761532333776855,-0.15630455409864116,0.6741288888174748,-0.04604169644634782,1.5145620294556341,0.7475285012988273,0.5687606043241162,-0.4071533609458661,2.726736385136414,3.312159535019784,0.8478026431297777,-0.13769618095212716,-0.04604169644634782,0.6741288888174748
2,454
Metal ion homeostasis
22
63
2.345231
0.019015
O75880,P23634,Q658P3,Q9Y487,P09601,P16615,P30519,Q9UM00,Q96A33,O95202,O75027,P51572,Q9Y639,P05067,Q9HD20,P55011,P05023,Q15904,O76024,P54709,Q6P4Q7,P20020
Processes and pathways
GO Biological process
msigdb_gobp
387,388,135,13,17,146,23,279,155,157,411,180,447,199,78,337,217,226,231,488,366,247
2155,1049,2116,411,387,2362,231,157,1002,884,2093,906,217,563,199,638,1684,730,17,629,1618,146,886,247,1056,388,1621,1946,23,860,2023,2198,180,488,337,614,1463,580,1670,1275,1469,2168,771,989,226,491,135,366,1324,1246,155,628,920,853,725,1569,78,592,1536,279,13,1045,447
-0.8294060110663698,-0.06419045128865337,-0.7849801986775056,0.6741288888174748,0.7329693277559037,-1.254512242689449,1.260450413484564,1.707357730711625,-0.02798234723534938,0.07854103289676595,-0.7629618451971119,0.06100140790540697,1.3103129401771128,0.41264038385623686,1.4199477449748363,0.28267536563664253,-0.44729726533392017,0.19900919256781674,3.312159535019784,0.2991791157749035,-0.4071533609458661,1.805183895274069,0.07854103289676595,1.1714327633031296,-0.06419045128865337,0.7329693277559037,-0.4071533609458661,-0.63348914849447,3.236770177586504,0.09599672590438624,-0.6976683628564239,-0.8743601688607926,1.572401341063591,0.522633995537609,0.8618984355820165,0.33196227773033055,-0.3086510615816659,0.3966486055076561,-0.42717118320069314,-0.19380576235625954,-0.3086510615816659,-0.8294060110663698,0.16499487134818433,-0.010011590331103102,1.2854711855638465,0.522633995537609,1.889836756325383,0.7764689191291888,-0.2127003983705159,-0.17500744981820085,1.7293410708596129,0.31560787666756207,0.06100140790540697,0.1133692286956227,0.2158976081565213,-0.3674382117784822,2.4470470431650044,0.3805855015225713,-0.34773878122711316,1.053540441532829,3.45129403999315,-0.04604169644634782,0.6293514881429343
2,454
Electron transport
15
34
2.339717
0.019298
O75306,P00403,O43169,P22695,Q86Y39,Q9H1E5,P21912,Q9UDW1,O95864,Q9H3N1,O14949,Q16134,O43676,Q9NX14,Q6DKK2
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
356,263,8,294,249,111,397,19,305,244,55,216,27,384,255
500,55,8,668,27,693,356,1769,503,1360,305,263,576,1861,1776,397,294,2159,1458,656,1661,2162,216,1137,845,1195,255,249,628,111,244,384,19,419
0.4915496270065848,2.652792387509817,3.5596030781502175,0.2494403407682528,3.123830761702728,0.23270776762766546,0.8051750649785682,-0.508336059704949,0.4915496270065848,-0.2507823308904216,0.9726826435647435,1.0932809768597807,0.3966486055076561,-0.5703894458091343,-0.508336059704949,0.7036707826264457,0.9998425933519748,-0.8294060110663698,-0.3086510615816659,0.2660959890242387,-0.42717118320069314,-0.8294060110663698,1.3226674254457509,-0.11918144832285707,0.1133692286956227,-0.15630455409864116,1.1455759264064622,1.1714327633031296,0.31560787666756207,2.0728909396765256,1.197099367809086,0.7475285012988273,3.3053793135556817,0.6741288888174748
2,454
Protein transmembrane import into intracellular organelle
7
12
2.330399
0.019785
O60830,Q99595,O95831,O43615,O14925,O75381,Q15388
Processes and pathways
GO Biological process
msigdb_gobp
0,2,160,355,165,335,308
165,355,0,335,1308,160,412,2120,308,512,2,1299
1.6741147827555374,0.8051750649785682,4.5070088122225345,0.8618984355820165,-0.2127003983705159,1.6852317773417498,0.6741288888174748,-0.7849801986775056,0.9726826435647435,0.4915496270065848,4.326911646644879,-0.19380576235625954
2,454
Schizophrenia
6
14
2.328012
0.019911
Q9NZJ7,Q9BQE5,P04062,P16615,O43681,P21964
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
195,3,71,146,151,123
151,231,71,146,123,2165,1165,2170,2172,824,3,2251,1326,195
1.7836865416843557,1.260450413484564,2.4909843512906855,1.805183895274069,1.9519654921535743,-0.8294060110663698,-0.13769618095212716,-0.8294060110663698,-0.8294060110663698,0.13065927350069947,4.125008978537356,-0.9428079094452866,-0.2127003983705159,1.4557332011052682
2,454
Mitochondrial calcium ion transport
6
14
2.326209
0.020007
Q9Y277,P21796,P45880,Q96TA2,O95202,Q10713
Processes and pathways
Reactome Pathways
msigdb_reactome
170,14,22,318,157,223
1741,157,14,473,22,223,1246,1604,318,382,725,592,170,1045
-0.48787858846125165,1.707357730711625,3.4383036215791014,0.5534510197557548,3.2506107876916754,1.2979142914342985,-0.17500744981820085,-0.3872427236161005,0.9177256601343565,0.7475285012988273,0.2158976081565213,0.3805855015225713,1.6629614855267152,-0.04604169644634782
2,454
Antiporter activity
6
9
2.325155
0.020064
P05141,P12235,P12236,Q9UBX3,Q02978,O95202
Functions
GO Molecular function
msigdb_gomf
285,299,175,48,281,157
157,285,607,299,175,508,395,281,48
1.707357730711625,1.026794211311183,0.34824294069161715,0.9862888463465534,1.6179808316611837,0.4915496270065848,0.7183502411380084,1.0401928182614306,2.726736385136414
2,454
Lipid droplet
8
29
2.316142
0.020551
Q9H6V9,Q8NBX0,Q99720,Q8NF37,P51572,Q01105,O43760,Q07065
Localization
GO Cellular component
msigdb_gocc
34,75,12,83,180,215,56,63
692,56,1426,784,832,670,1772,1811,291,864,738,180,1817,215,63,1784,745,590,75,83,2257,428,1350,12,1381,34,1069,1329,394
0.23270776762766546,2.610978516529192,-0.2892607576646261,0.14786758317336363,0.1133692286956227,0.2494403407682528,-0.508336059704949,-0.5289062519642656,1.013344258369898,0.09599672590438624,0.19900919256781674,1.572401341063591,-0.5289062519642656,1.3226674254457509,2.560087810726942,-0.508336059704949,0.19900919256781674,0.3805855015225713,2.4558814235873045,2.3755090350781054,-0.9659009950668074,0.6592655098222254,-0.23169227715850227,3.4642312200666168,-0.2507823308904216,2.9918277160543005,-0.06419045128865337,-0.2127003983705159,0.7329693277559037
2,454
Abnormality of the biliary system
25
90
2.315909
0.020563
Q9NSD9,P09601,P28288,O43681,Q96A33,O95202,Q13510,Q14108,Q14739,P61916,Q9NZJ7,P22830,P04062,Q9UBM7,O75381,Q16134,Q10713,Q15904,P02545,Q9UJW0,O15118,Q5XKP0,Q9UJS0,P21964,Q9Y4P3
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
259,17,277,151,155,157,45,50,52,317,195,67,71,201,335,216,223,226,99,228,102,240,250,123,128
709,102,151,904,335,480,1683,157,1837,336,99,71,2293,1003,1100,925,1838,1363,17,1101,834,1310,2303,1861,620,2097,1775,2400,123,67,277,961,1814,1495,787,2195,1661,1686,2416,483,2233,1082,1999,1749,413,698,2165,1549,1690,721,1084,2336,317,2106,1669,602,1591,2353,223,2027,45,50,52,465,226,216,680,1786,240,556,1015,1822,2030,2300,2172,1935,155,872,992,650,1681,259,195,201,1251,1885,250,228,1219,128
0.2158976081565213,2.1608111690827836,1.7836865416843557,0.06100140790540697,0.8618984355820165,0.5380756588239767,-0.44729726533392017,1.707357730711625,-0.5495903224499785,0.8618984355820165,2.1896121397888693,2.4909843512906855,-1.0360339359435122,-0.02798234723534938,-0.1007594861270674,0.04337709946176049,-0.5495903224499785,-0.2507823308904216,3.312159535019784,-0.1007594861270674,0.1133692286956227,-0.2127003983705159,-1.059701599588804,-0.5703894458091343,0.31560787666756207,-0.7629618451971119,-0.508336059704949,-1.5127841056693392,1.9519654921535743,2.5257174263669264,1.053540441532829,0.00787137682826172,-0.5289062519642656,-0.32814340269650955,0.14786758317336363,-0.8743601688607926,-0.42717118320069314,-0.44729726533392017,-1.6764363701881217,0.5380756588239767,-0.9198544438847963,-0.08242943604018182,-0.6761532333776855,-0.48787858846125165,0.6741288888174748,0.23270776762766546,-0.8294060110663698,-0.3674382117784822,-0.44729726533392017,0.2158976081565213,-0.08242943604018182,-1.1558676625729167,0.9177256601343565,-0.7629618451971119,-0.42717118320069314,0.36445047971555095,-0.3872427236161005,-1.204872765188523,1.2979142914342985,-0.6976683628564239,2.8227904319852435,2.702273873382328,2.685863124657544,0.5687606043241162,1.2854711855638465,1.3226674254457509,0.2494403407682528,-0.508336059704949,1.2225783190817734,0.42856142165780864,-0.02798234723534938,-0.5289062519642656,-0.6976683628564239,-1.0360339359435122,-0.8294060110663698,-0.6123376390093992,1.7293410708596129,0.09599672590438624,-0.010011590331103102,0.28267536563664253,-0.42717118320069314,1.132575350613476,1.4557332011052682,1.4199477449748363,-0.17500744981820085,-0.5703894458091343,1.1714327633031296,1.2854711855638465,-0.15630455409864116,1.9416897191826263
2,454
Steroid biosynthesis
7
15
2.315799
0.020569
P48449,P37268,Q9UBM7,P14324,Q53GQ0,Q14739,Q16850
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
291,10,201,171,145,52,61
670,171,10,291,2406,2002,52,374,745,61,145,873,1643,201,952
0.2494403407682528,1.6405450993859982,3.48994747351802,1.013344258369898,-1.5395856690495455,-0.6761532333776855,2.685863124657544,0.7620282155096825,0.19900919256781674,2.585631778102509,1.8371768966766115,0.09599672590438624,-0.4071533609458661,1.4199477449748363,0.02566734622848883
2,454
The citric acid tca cycle and respiratory electron transport
36
84
2.305478
0.02114
O00483,O75880,O95168,P00403,Q8IUX1,P21796,Q15120,P21912,Q9UDW1,P06576,O43676,Q9Y6M9,O75964,P22695,P48163,O75947,O14949,Q9NPL8,P20674,Q9BQ95,P51553,Q13423,P09622,Q9P032,P24539,O00330,P53985,Q9Y375,Q16134,P56385,O75306,P35613,P56134,P13073,Q86Y39,Q9NX14
Processes and pathways
Reactome Pathways
msigdb_reactome
500,387,503,263,140,14,522,397,19,529,27,419,40,294,553,551,55,188,440,585,578,72,325,468,80,339,214,343,216,475,356,107,363,115,249,384
339,500,55,27,1358,958,693,356,2292,1769,387,551,40,503,1360,2064,263,529,2302,1838,885,576,325,1616,2095,766,1335,115,1861,732,1776,440,14,397,294,1995,80,1104,2159,1458,656,107,754,1544,1661,2101,1967,2181,553,2423,2162,2073,578,1026,214,363,475,1501,1927,1467,72,522,216,1137,845,1527,1437,249,140,647,969,2369,1936,585,1208,1040,1325,188,384,468,1645,19,343,419
0.8478026431297777,0.4915496270065848,2.652792387509817,3.123830761702728,-0.2507823308904216,0.00787137682826172,0.23270776762766546,0.8051750649785682,-1.0360339359435122,-0.508336059704949,0.7329693277559037,0.42856142165780864,2.938995264788679,0.4915496270065848,-0.2507823308904216,-0.7410713309240917,1.0932809768597807,0.4601935811647347,-1.059701599588804,-0.5495903224499785,0.07854103289676595,0.3966486055076561,0.8899224210436362,-0.4071533609458661,-0.7629618451971119,0.16499487134818433,-0.23169227715850227,2.0230322589366674,-0.5703894458091343,0.19900919256781674,-0.508336059704949,0.6293514881429343,3.4383036215791014,0.7036707826264457,0.9998425933519748,-0.6761532333776855,2.4025173766417525,-0.1007594861270674,-0.8294060110663698,-0.3086510615816659,0.2660959890242387,2.1511554521015115,0.18204184259460307,-0.3674382117784822,-0.42717118320069314,-0.7629618451971119,-0.6547605908794988,-0.851816319929439,0.42856142165780864,-1.7894811458568527,-0.8294060110663698,-0.7410713309240917,0.3966486055076561,-0.04604169644634782,1.3349780380688931,0.7764689191291888,0.5534510197557548,-0.32814340269650955,-0.6123376390093992,-0.3086510615816659,2.4909843512906855,0.47590583856156266,1.3226674254457509,-0.11918144832285707,0.1133692286956227,-0.34773878122711316,-0.2892607576646261,1.1714327633031296,1.8688709393675171,0.28267536563664253,0.00787137682826172,-1.279574662903545,-0.6123376390093992,0.3966486055076561,-0.15630455409864116,-0.04604169644634782,-0.2127003983705159,1.5145620294556341,0.7475285012988273,0.5687606043241162,-0.4071533609458661,3.3053793135556817,0.8478026431297777,0.6741288888174748
2,454
Postural tremor
7
14
2.302156
0.021326
O75306,Q9H6K4,O95140,Q9NR77,Q14108,P20700,O14773
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
356,141,273,49,50,345,351
351,594,356,273,1002,345,373,658,1240,50,2269,141,49,1482
0.8194413803231336,0.36445047971555095,0.8051750649785682,1.0668374397151672,-0.02798234723534938,0.8336504314439626,0.7620282155096825,0.2660959890242387,-0.17500744981820085,2.702273873382328,-0.9891352838762909,1.8688709393675171,2.7104484304643575,-0.3086510615816659
2,454
serine protease
10
17
2.296081
0.021671
Q9HB40,P13798,P67812,Q4J6C6,P42785,Q16740,P10619,Q9H3G5,O43464,O14773
Functions
Panther Protein class
panther_protein_class
164,161,37,295,73,74,454,212,272,351
351,272,454,1860,161,2021,787,73,2199,37,74,295,1788,485,212,164,1987
0.8194413803231336,1.0668374397151672,0.5840049324470407,-0.5703894458091343,1.6852317773417498,-0.6976683628564239,0.14786758317336363,2.464692228627964,-0.8743601688607926,2.9692910588506276,2.4558814235873045,0.9998425933519748,-0.508336059704949,0.5380756588239767,1.3472450660860968,1.6852317773417498,-0.6547605908794988
2,454
Nadh dehydrogenase complex assembly
9
19
2.285852
0.022263
O75306,Q9H061,Q86Y39,Q8IUX1,Q9P032,Q9Y375,O43676,Q9NX14,Q9Y6M9
Processes and pathways
GO Biological process
msigdb_gobp
356,4,249,140,468,343,27,384,419
27,693,356,1769,503,1360,2159,1137,845,1437,249,140,647,4,1040,384,468,343,419
3.123830761702728,0.23270776762766546,0.8051750649785682,-0.508336059704949,0.4915496270065848,-0.2507823308904216,-0.8294060110663698,-0.11918144832285707,0.1133692286956227,-0.2892607576646261,1.1714327633031296,1.8688709393675171,0.28267536563664253,3.7831470025227314,-0.04604169644634782,0.7475285012988273,0.5687606043241162,0.8478026431297777,0.6741288888174748
2,454
Rac2 gtpase cycle
6
27
2.281899
0.022495
P42167,Q13505,O15173,Q86XL3,Q14739,Q9Y2A7
Processes and pathways
Reactome Pathways
msigdb_reactome
191,97,39,43,52,251
39,1002,765,884,671,986,191,1897,717,389,738,946,1109,1553,770,97,1406,52,847,722,43,1479,2092,878,251,534,284
2.938995264788679,-0.02798234723534938,0.16499487134818433,0.07854103289676595,0.2494403407682528,-0.010011590331103102,1.4793854803467268,-0.5913048144722944,0.2158976081565213,0.7329693277559037,0.19900919256781674,0.02566734622848883,-0.1007594861270674,-0.3674382117784822,0.16499487134818433,2.1991575594968427,-0.26997150484729665,2.685863124657544,0.1133692286956227,0.2158976081565213,2.9007217131059995,-0.3086510615816659,-0.7410713309240917,0.09599672590438624,1.1714327633031296,0.4601935811647347,1.0401928182614306
2,454
Overlap between signal transduction pathways contributing to lmna laminopathies
7
13
2.278738
0.022683
P42167,P55209,P02545,P50402,O60725,O75844,Q9Y2U8
Processes and pathways
WikiPathways
msigdb_wp
191,352,99,389,42,106,534
42,106,99,540,1105,986,191,737,1497,389,352,701,534
2.9160855263377137,2.1511554521015115,2.1896121397888693,0.4444122970173833,-0.1007594861270674,-0.010011590331103102,1.4793854803467268,0.19900919256781674,-0.32814340269650955,0.7329693277559037,0.8194413803231336,0.23270776762766546,0.4601935811647347
2,454
Abnormal saccadic eye movements
6
17
2.275187
0.022895
Q10713,O75306,P04062,O95140,Q8IV08,O14773
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
223,356,71,273,93,351
1834,351,1512,356,273,71,2096,1395,1057,1006,1234,223,359,93,1350,1421,1045
-0.5495903224499785,0.8194413803231336,-0.34773878122711316,0.8051750649785682,1.0668374397151672,2.4909843512906855,-0.7629618451971119,-0.26997150484729665,-0.06419045128865337,-0.02798234723534938,-0.17500744981820085,1.2979142914342985,0.7908510559681761,2.2464793614272396,-0.23169227715850227,-0.26997150484729665,-0.04604169644634782
2,454
Oxidoreductase activity acting on the ch ch group of donors nad or nadp as acceptor
6
11
2.270049
0.023205
Q8N8N7,Q9UBM7,Q8N4Q0,Q9H7Z7,Q14739,Q9NZ01
Functions
GO Molecular function
msigdb_gomf
230,201,177,148,52,149
1546,698,52,490,374,177,230,1447,148,149,201
-0.3674382117784822,0.23270776762766546,2.685863124657544,0.522633995537609,0.7620282155096825,1.595266862974184,1.2729833260513288,-0.2892607576646261,1.805183895274069,1.805183895274069,1.4199477449748363
2,454
Response to endoplasmic reticulum stress
19
69
2.268457
0.023301
P16615,Q9UM00,Q96A33,O95831,P51572,Q9UBU6,P27824,P57088,Q6ZXV5,Q9UBV2,P46379,O00330,Q9BUN8,O76024,Q8TCT9,Q9H3N1,O60313,Q9Y4P3,O75955
Processes and pathways
GO Biological process
msigdb_gobp
146,279,155,160,180,184,314,193,327,202,81,339,84,231,105,244,245,128,126
339,998,1307,1181,1836,245,126,231,1488,654,1002,160,749,1003,1334,504,1653,1618,146,1655,1745,1946,314,753,1367,508,81,1497,180,1461,1817,193,1627,1691,2124,1165,868,842,2344,915,1932,327,1287,798,2128,571,105,2172,353,155,428,628,1291,1983,2269,1294,84,244,855,1800,184,202,279,1482,2062,652,1220,128,394
0.8478026431297777,-0.02798234723534938,-0.2127003983705159,-0.15630455409864116,-0.5495903224499785,1.184289682202268,1.9416897191826263,1.260450413484564,-0.32814340269650955,0.2660959890242387,-0.02798234723534938,1.6852317773417498,0.18204184259460307,-0.02798234723534938,-0.23169227715850227,0.4915496270065848,-0.42717118320069314,-0.4071533609458661,1.805183895274069,-0.42717118320069314,-0.48787858846125165,-0.63348914849447,0.9315455033685286,0.18204184259460307,-0.2507823308904216,0.4915496270065848,2.393539051580102,-0.32814340269650955,1.572401341063591,-0.3086510615816659,-0.5289062519642656,1.4557332011052682,-0.4071533609458661,-0.44729726533392017,-0.7849801986775056,-0.13769618095212716,0.09599672590438624,0.1133692286956227,-1.180291858569714,0.06100140790540697,-0.6123376390093992,0.8899224210436362,-0.19380576235625954,0.14786758317336363,-0.7849801986775056,0.41264038385623686,2.1608111690827836,-0.8294060110663698,0.8194413803231336,1.7293410708596129,0.6592655098222254,0.31560787666756207,-0.19380576235625954,-0.6547605908794988,-0.9891352838762909,-0.19380576235625954,2.3664570959280136,1.197099367809086,0.1133692286956227,-0.508336059704949,1.549382379998421,1.4199477449748363,1.053540441532829,-0.3086510615816659,-0.7193072862402492,0.28267536563664253,-0.15630455409864116,1.9416897191826263,0.7329693277559037
2,454
Proton transmembrane transporter activity
15
31
2.259404
0.023858
P05141,Q93050,P00403,O75964,Q13423,P51790,P12235,Q9Y487,O00400,P24539,P56134,Q9UDW1,P13073,O95202,P20674
Functions
GO Molecular function
msigdb_gomf
285,36,263,40,72,395,299,13,173,80,363,19,115,157,440
173,551,40,157,263,285,529,576,766,299,115,440,2295,2325,80,1104,656,754,1685,2023,2181,395,363,475,614,616,72,36,19,1385,13
1.6292815636710885,0.42856142165780864,2.938995264788679,1.707357730711625,1.0932809768597807,1.026794211311183,0.4601935811647347,0.3966486055076561,0.16499487134818433,0.9862888463465534,2.0230322589366674,0.6293514881429343,-1.0360339359435122,-1.1074820632844848,2.4025173766417525,-0.1007594861270674,0.2660959890242387,0.18204184259460307,-0.44729726533392017,-0.6976683628564239,-0.851816319929439,0.7183502411380084,0.7764689191291888,0.5534510197557548,0.33196227773033055,0.33196227773033055,2.4909843512906855,2.9768207877432644,3.3053793135556817,-0.2507823308904216,3.45129403999315
2,454
Progressive neurologic deterioration
9
18
2.25054
0.024415
Q9NZJ7,P04062,P16278,Q5XKP0,O43681,P54802,Q9NPL8,P20700,Q10713
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
195,71,142,240,151,248,188,345,223
151,71,638,142,345,397,1458,1967,248,658,1817,223,2003,240,1721,2013,188,195
1.7836865416843557,2.4909843512906855,0.28267536563664253,1.8583391561768707,0.8336504314439626,0.7036707826264457,-0.3086510615816659,-0.6547605908794988,1.1714327633031296,0.2660959890242387,-0.5289062519642656,1.2979142914342985,-0.6761532333776855,1.2225783190817734,-0.4675326981198081,-0.6761532333776855,1.5145620294556341,1.4557332011052682
2,454
Ceramide metabolic process
8
14
2.245574
0.024731
Q53H12,P04062,Q13510,P17900,O43464,Q96G23,O95470,O15269
Processes and pathways
GO Biological process
msigdb_gobp
426,71,45,144,272,21,116,316
316,272,116,71,552,713,638,144,1713,45,426,21,467,2244
0.9177256601343565,1.0668374397151672,2.0129711959011636,2.4909843512906855,0.42856142165780864,0.2158976081565213,0.28267536563664253,1.8371768966766115,-0.4675326981198081,2.8227904319852435,0.6592655098222254,3.264391530678441,0.5687606043241162,-0.9198544438847963
2,454