term stringlengths 2 121 | overlap int64 6 281 | setsize int64 7 499 | score float64 1.96 10.6 | pval float64 0 0.05 | edge stringlengths 41 1.97k | type stringclasses 5 values | subtype stringclasses 24 values | subtype_key stringclasses 24 values | edge_idxs stringlengths 11 1.17k | ann_idxs stringlengths 19 2.31k | ann_vals stringlengths 124 9.94k | sig_size int64 2.2k 3.73k |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Proteasome, subunit alpha/beta [IPR001353] | 6 | 14 | 2.640076 | 0.008289 | P28070,P25786,P20618,P28074,P49721,P28072 | Sequence | InterPro Family | interpro_family | 129,257,167,147,59,60 | 2698,167,257,1193,991,1656,2661,129,60,147,996,59,297,604 | -0.5795719264467128,1.5982387622118392,1.1713983468947904,0.04865771165184635,0.16125438838387834,-0.156840189674286,-0.5556499880877578,1.8362710532052997,2.897905946491273,1.7375864773292968,0.16125438838387834,2.970948746307514,1.0260036903302046,0.4927328204863091 | 3,329 |
Cholesterol metabolism | 7 | 27 | 2.638189 | 0.008335 | Q16850,Q15125,P37268,Q15392,Q15800,Q14739,P04062 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 193,99,7,12,173,26,191 | 400,1109,873,3058,2455,191,2412,2987,960,7,1146,795,2672,3137,1003,1488,3215,26,99,1807,12,2576,173,193,668,240,651 | 0.7728635640285376,0.09382756959687372,0.22829447058781055,-0.8463621203281708,-0.46049272408808617,1.4372284667550546,-0.4368340474097858,-0.7729219653555064,0.18364368033144304,5.721954661682018,0.07126469850274689,0.2949552633600194,-0.5556499880877578,-0.9451070759599981,0.16125438838387834,-0.08792739806811385,-1.1202684582751312,3.908602733869772,2.2051248024821013,-0.203017633379766,4.796997022347357,-0.5079660590613365,1.578216255499028,1.4372284667550546,0.4271675731360321,1.2332184926667917,0.4490621451928765 | 3,329 |
Sterol metabolism | 7 | 27 | 2.638189 | 0.008335 | Q16850,Q15125,P37268,Q15392,Q15800,Q14739,P04062 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 193,99,7,12,173,26,191 | 400,1109,873,3058,2455,191,2412,2987,960,7,1146,795,2672,3137,1003,1488,3215,26,99,1807,12,2576,173,193,668,240,651 | 0.7728635640285376,0.09382756959687372,0.22829447058781055,-0.8463621203281708,-0.46049272408808617,1.4372284667550546,-0.4368340474097858,-0.7729219653555064,0.18364368033144304,5.721954661682018,0.07126469850274689,0.2949552633600194,-0.5556499880877578,-0.9451070759599981,0.16125438838387834,-0.08792739806811385,-1.1202684582751312,3.908602733869772,2.2051248024821013,-0.203017633379766,4.796997022347357,-0.5079660590613365,1.578216255499028,1.4372284667550546,0.4271675731360321,1.2332184926667917,0.4490621451928765 | 3,329 |
Alcohol metabolic process | 14 | 88 | 2.632208 | 0.008483 | Q16850,Q15125,P37268,P48449,P00374,Q15392,O75874,Q8WTV0,Q15800,P48735,P35270,Q14739,O15270,P04062 | Processes and pathways | GO Biological process | msigdb_gobp | 193,99,7,72,41,12,76,14,173,22,86,26,216,191 | 3231,400,765,216,2651,1310,1109,76,702,873,2820,41,3058,2455,191,2048,1359,1586,2119,2412,3034,1991,1589,2354,3084,2987,1996,992,3134,86,960,7,2126,705,72,22,2422,3015,1436,2668,2514,392,1733,1146,2902,3018,795,2672,1802,3137,2430,1003,888,1488,437,1285,3215,530,26,1876,99,1807,12,2576,173,1679,193,893,668,2384,1885,857,14,3177,2847,2391,1895,2393,285,1256,2214,631,1345,838,240,651,3129,1412 | -1.1962933336355144,0.7728635640285376,0.31709249325645056,1.2947503089070345,-0.5556499880877578,-0.01943091003423015,0.09382756959687372,2.546140982982583,0.3832587355956147,0.22829447058781055,-0.6516625684987778,3.4022527556665043,-0.8463621203281708,-0.46049272408808617,1.4372284667550546,-0.29594995909674393,-0.04221734363056225,-0.13382247009957884,-0.3193053506689896,-0.4368340474097858,-0.82182395495969,-0.27264384148485665,-0.13382247009957884,-0.41322685082973565,-0.8709590302873479,-0.7729219653555064,-0.27264384148485665,0.16125438838387834,-0.9451070759599981,2.3766152947125034,0.18364368033144304,5.721954661682018,-0.3193053506689896,0.3832587355956147,2.6581035741477934,4.1646493114890495,-0.4368340474097858,-0.7973440593945568,-0.06504940216522562,-0.5556499880877578,-0.4842032649662147,0.7941527445250331,-0.17990513363585875,0.07126469850274689,-0.6999979046598092,-0.7973440593945568,0.2949552633600194,-0.5556499880877578,-0.203017633379766,-0.9451070759599981,-0.4368340474097858,0.16125438838387834,0.22829447058781055,-0.08792739806811385,0.7087780760645422,0.0033102074454991735,-1.1202684582751312,0.5796069942263014,3.908602733869772,-0.2261780242890793,2.2051248024821013,-0.203017633379766,4.796997022347357,-0.5079660590613365,1.578216255499028,-0.156840189674286,1.4372284667550546,0.22829447058781055,0.4271675731360321,-0.41322685082973565,-0.2261780242890793,0.25055651741635415,4.747880134126402,-1.0198015679513603,-0.6516625684987778,-0.41322685082973565,-0.2261780242890793,-0.41322685082973565,1.0677113479047518,0.026006314080828572,-0.34271037257634035,0.4709171468581955,-0.01943091003423015,0.27277669272882116,1.2332184926667917,0.4490621451928765,-0.9203310164531874,-0.04221734363056225 | 3,329 |
Disproportionate short limb short stature | 11 | 19 | 2.623545 | 0.008702 | Q15125,Q32P28,Q6DKJ4,Q03164,Q9UBM7,Q15392,Q7LGA3,O15228,O75718,Q14739,Q7RTS9 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 99,37,325,551,240,12,426,489,335,26,28 | 575,489,2860,335,3098,2290,1195,2179,551,26,99,12,37,325,426,28,3163,1334,240 | 0.5145094059098909,0.6228142321842982,-0.6758024598264976,0.9211394780417321,-0.8956151662633678,-0.38967075507457544,0.04865771165184635,-0.34271037257634035,0.5579462590868453,3.908602733869772,2.2051248024821013,4.796997022347357,3.596143058067744,0.9421810860656006,0.7301764410183317,3.874170839925339,-0.9948418387058783,-0.01943091003423015,1.2332184926667917 | 3,329 |
Peptide binding | 12 | 76 | 2.611496 | 0.009015 | P10321,Q15392,Q9UIQ6,Q8WTV0,Q03518,P42892,O43731,P55786,Q9NZ08,Q92973,P24390,O60925 | Functions | GO Molecular function | msigdb_gomf | 291,12,13,14,110,82,19,242,87,282,30,319 | 524,1640,1464,841,842,1354,2340,19,2409,2859,319,2168,2455,614,615,3264,1469,1585,291,617,1473,2708,2290,30,2461,1526,1479,2124,1363,1530,1849,879,82,1999,2609,2610,2128,822,997,1116,1601,242,3017,1541,728,2565,110,1859,2871,2372,2718,1875,3174,1613,12,668,799,858,14,282,975,2635,1335,1761,3223,345,1058,606,2399,909,87,1064,634,13,3181,1413 | 0.5796069942263014,-0.156840189674286,-0.08792739806811385,0.25055651741635415,0.25055651741635415,-0.04221734363056225,-0.41322685082973565,4.266012245132118,-0.4368340474097858,-0.6758024598264976,0.9421810860656006,-0.34271037257634035,-0.46049272408808617,0.4709171468581955,0.4709171468581955,-1.3760283681740184,-0.08792739806811385,-0.13382247009957884,1.0468743338568534,0.4709171468581955,-0.08792739806811385,-0.5795719264467128,-0.38967075507457544,3.8223910414490736,-0.46049272408808617,-0.1108516474371695,-0.08792739806811385,-0.3193053506689896,-0.04221734363056225,-0.1108516474371695,-0.2261780242890793,0.22829447058781055,2.452198066890038,-0.27264384148485665,-0.5317815003956151,-0.5317815003956151,-0.3193053506689896,0.27277669272882116,0.16125438838387834,0.09382756959687372,-0.13382247009957884,1.2126440410867516,-0.7973440593945568,-0.1108516474371695,0.3612439724526373,-0.5079660590613365,2.0509750105284508,-0.2261780242890793,-0.6758024598264976,-0.41322685082973565,-0.5795719264467128,-0.2261780242890793,-1.0198015679513603,-0.13382247009957884,4.796997022347357,0.4271675731360321,0.2949552633600194,0.25055651741635415,4.747880134126402,1.0677113479047518,0.18364368033144304,-0.5317815003956151,-0.01943091003423015,-0.17990513363585875,-1.1455448923699307,0.900063101102262,0.1388221277863417,0.4927328204863091,-0.41322685082973565,0.22829447058781055,2.3766152947125034,0.1388221277863417,0.4709171468581955,4.780639478907166,-1.0198015679513603,-0.04221734363056225 | 3,329 |
Signaling | 8 | 17 | 2.602475 | 0.009255 | Q96PC5,O14641,P43490,P51858,Q8WUJ1,Q5SW96,O15173,O00264 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 456,349,5,643,141,668,114,524 | 524,349,114,1577,1434,5,643,1149,1281,965,2434,668,669,141,456,1051,1134 | 0.5796069942263014,0.8789517589290488,1.9732758301648015,-0.13382247009957884,-0.06504940216522562,6.0461655933051235,0.4490621451928765,0.07126469850274689,0.0033102074454991735,0.18364368033144304,-0.4368340474097858,0.4271675731360321,0.4271675731360321,1.777144026318633,0.6873428903362069,0.1388221277863417,0.09382756959687372 | 3,329 |
Mitochondrial protein import | 7 | 35 | 2.600803 | 0.009301 | P21796,Q99595,Q9NS69,O14925,Q8N4Q1,Q5JRX3,Q8N4H5 | Processes and pathways | Reactome Pathways | msigdb_reactome | 64,35,16,241,50,124,92 | 241,701,812,2699,988,1987,1718,2168,1782,2228,1074,3099,266,1265,64,3085,2606,1436,888,1610,1613,1614,124,92,50,35,2391,1396,16,472,652,3145,488,1414,1103 | 1.2126440410867516,0.3832587355956147,0.27277669272882116,-0.5795719264467128,0.16125438838387834,-0.27264384148485665,-0.17990513363585875,-0.34271037257634035,-0.203017633379766,-0.3661653856138045,0.11634661657064145,-0.8956151662633678,1.1092852207351331,0.0033102074454991735,2.824517962466285,-0.8709590302873479,-0.5317815003956151,-0.06504940216522562,0.22829447058781055,-0.13382247009957884,-0.13382247009957884,-0.13382247009957884,1.8951501094270817,2.2815903464027634,3.1340610333831447,3.64862783763913,-0.41322685082973565,-0.04221734363056225,4.533482019529468,0.6658706672953714,0.4490621451928765,-0.9451070759599981,0.6443611882223067,-0.04221734363056225,0.11634661657064145 | 3,329 |
Intrinsic component of endoplasmic reticulum membrane | 13 | 52 | 2.586246 | 0.009703 | Q9Y282,Q15125,Q15041,O75844,Q8TCT8,Q16799,Q86YN1,Q15629,Q9UBM7,Q86XL3,Q03518,Q9NZ01,O95470 | Localization | GO Cellular component | msigdb_gocc | 97,99,199,131,71,102,264,74,240,107,110,215,91 | 2036,3009,2167,1187,131,744,91,614,615,291,2461,1361,3037,2181,565,1541,110,2571,2835,3065,199,99,74,102,1244,1551,107,264,715,2088,1816,71,3127,2807,778,2320,626,1558,1499,2637,468,1342,1099,215,397,1976,2027,240,1637,97,3220,1104 | -0.29594995909674393,-0.7973440593945568,-0.34271037257634035,0.04865771165184635,1.8165897720528055,0.3391886435203106,2.300644481221058,0.4709171468581955,0.4709171468581955,1.0468743338568534,-0.46049272408808617,-0.04221734363056225,-0.82182395495969,-0.34271037257634035,0.5362471404769038,-0.1108516474371695,2.0509750105284508,-0.5079660590613365,-0.6516625684987778,-0.8463621203281708,1.4169669380234817,2.2051248024821013,2.6022259510613153,2.1282554740320596,0.026006314080828572,-0.1108516474371695,2.089667102484907,1.1300224418606861,0.3832587355956147,-0.29594995909674393,-0.203017633379766,2.713776438256748,-0.9203310164531874,-0.6275777989300914,0.31709249325645056,-0.38967075507457544,0.4709171468581955,-0.1108516474371695,-0.08792739806811385,-0.5317815003956151,0.6658706672953714,-0.01943091003423015,0.11634661657064145,1.3151976269095578,0.7941527445250331,-0.24938664580266173,-0.27264384148485665,1.2332184926667917,-0.13382247009957884,2.243407596862186,-1.1202684582751312,0.11634661657064145 | 3,329 |
Steroid binding | 8 | 22 | 2.582714 | 0.009803 | P21796,P45880,P38435,O15118,O15173,P30536,Q14108,P04062 | Functions | GO Molecular function | msigdb_gomf | 64,67,229,400,114,212,156,191 | 524,400,114,1109,873,2497,191,845,2706,64,1431,1788,212,960,229,67,795,156,1448,2323,1896,429 | 0.5796069942263014,0.7728635640285376,1.9732758301648015,0.09382756959687372,0.22829447058781055,-0.4842032649662147,1.4372284667550546,0.25055651741635415,-0.5795719264467128,2.824517962466285,-0.06504940216522562,-0.203017633379766,1.3151976269095578,0.18364368033144304,1.253760908657221,2.750779178310562,0.2949552633600194,1.678038142292685,-0.06504940216522562,-0.38967075507457544,-0.2261780242890793,0.7301764410183317 | 3,329 |
Organic acid transmembrane transporter activity | 8 | 21 | 2.575479 | 0.01001 | P53985,Q9H2D1,Q9Y619,Q9UBX3,Q96QD8,Q02978,P41440,O95563 | Functions | GO Molecular function | msigdb_gomf | 413,69,39,398,370,106,55,93 | 2947,2817,1718,93,433,1584,55,1664,413,106,1375,2137,587,370,69,946,1901,1828,398,652,39 | -0.7485572109498702,-0.6516625684987778,-0.17990513363585875,2.262511421655104,0.7087780760645422,-0.13382247009957884,3.0073424154788886,-0.156840189674286,0.7515381995844014,2.089667102484907,-0.04221734363056225,-0.3193053506689896,0.5145094059098909,0.8578052533050858,2.7322889967086703,0.2059902824751761,-0.2261780242890793,-0.203017633379766,0.7941527445250331,0.4490621451928765,3.52590265888114 | 3,329 |
Sensorimotor neuropathy | 12 | 33 | 2.571699 | 0.01012 | Q9Y2R0,Q9NSE4,O95831,Q9NR77,P07602,O60313,P41440,P00846,O15270,Q15120,Q7LG56,Q8N2K0 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 134,265,105,15,143,217,55,24,216,250,189,94 | 740,216,217,450,105,3302,24,2821,845,306,143,1474,2415,2508,880,55,2423,1600,2361,2713,2717,250,514,189,94,444,3258,15,265,3051,866,134,1513 | 0.3391886435203106,1.2947503089070345,1.2947503089070345,0.6873428903362069,2.1089741942010813,-1.9922392137678377,4.04563696990221,-0.6516625684987778,0.25055651741635415,0.9841607712980948,1.7573792946827045,-0.08792739806811385,-0.4368340474097858,-0.4842032649662147,0.22829447058781055,3.0073424154788886,-0.4368340474097858,-0.13382247009957884,-0.41322685082973565,-0.5795719264467128,-0.5795719264467128,1.1920373832406677,0.6012295760038491,1.457459585216246,2.262511421655104,0.7087780760645422,-1.3243326104741977,4.533482019529468,1.1300224418606861,-0.82182395495969,0.25055651741635415,1.8165897720528055,-0.08792739806811385 | 3,329 |
Metallopeptidase activity | 18 | 43 | 2.570133 | 0.010166 | Q9HD42,Q7Z2K6,P78536,O75844,P02786,Q9UIQ6,O95630,Q969V3,P42892,P55786,Q96TA2,Q92905,Q99797,Q9NZ08,Q9BYT8,Q5JRX3,O75976,P09960 | Functions | GO Molecular function | msigdb_gomf | 590,455,479,131,477,13,576,340,82,242,467,602,570,87,345,124,254,434 | 1182,1573,1106,2286,1987,131,254,576,477,434,2460,1473,1593,3150,2418,82,2712,1535,621,1734,242,479,888,124,1377,2381,455,602,340,2091,2636,467,570,717,345,1763,590,1017,2975,2695,87,13,1513 | 0.04865771165184635,-0.13382247009957884,0.09382756959687372,-0.38967075507457544,-0.27264384148485665,1.8165897720528055,1.1713983468947904,0.5145094059098909,0.6443611882223067,0.7087780760645422,-0.46049272408808617,-0.08792739806811385,-0.13382247009957884,-0.9699438469321776,-0.4368340474097858,2.452198066890038,-0.5795719264467128,-0.1108516474371695,0.4709171468581955,-0.17990513363585875,1.2126440410867516,0.6443611882223067,0.22829447058781055,1.8951501094270817,-0.04221734363056225,-0.41322685082973565,0.6873428903362069,0.4927328204863091,0.9211394780417321,-0.29594995909674393,-0.5317815003956151,0.6658706672953714,0.5362471404769038,0.3832587355956147,0.900063101102262,-0.17990513363585875,0.5145094059098909,0.16125438838387834,-0.7485572109498702,-0.5556499880877578,2.3766152947125034,4.780639478907166,-0.08792739806811385 | 3,329 |
Endoplasmic reticulum golgi intermediate compartment | 10 | 50 | 2.565512 | 0.010302 | Q8N511,Q9Y282,Q92614,Q02818,P80303,Q03518,Q15363,Q8IUR0,P24390,P49257 | Localization | GO Cellular component | msigdb_gocc | 327,97,262,73,46,110,115,315,30,220 | 1355,788,1781,592,1232,1523,30,681,2461,1363,220,793,2562,2181,2613,794,1272,1538,46,73,110,887,1369,710,967,2800,115,1747,895,315,327,938,262,2263,2320,3023,1214,1893,1894,329,758,1825,2852,2217,1134,97,1461,2033,2856,422 | -0.04221734363056225,0.2949552633600194,-0.203017633379766,0.4927328204863091,0.026006314080828572,-0.1108516474371695,3.8223910414490736,0.40523318577404505,-0.46049272408808617,-0.04221734363056225,1.2947503089070345,0.2949552633600194,-0.5079660590613365,-0.34271037257634035,-0.5317815003956151,0.2949552633600194,0.0033102074454991735,-0.1108516474371695,3.313351901724999,2.6581035741477934,2.0509750105284508,0.22829447058781055,-0.04221734363056225,0.3832587355956147,0.18364368033144304,-0.6275777989300914,1.9732758301648015,-0.17990513363585875,0.22829447058781055,0.9631881196187747,0.9421810860656006,0.2059902824751761,1.1507267582378766,-0.3661653856138045,-0.38967075507457544,-0.7973440593945568,0.04865771165184635,-0.2261780242890793,-0.2261780242890793,0.9421810860656006,0.3391886435203106,-0.203017633379766,-0.6516625684987778,-0.34271037257634035,0.09382756959687372,2.243407596862186,-0.06504940216522562,-0.27264384148485665,-0.6516625684987778,0.7515381995844014 | 3,329 |
Sphingolipid metabolism | 8 | 10 | 2.557532 | 0.010542 | Q16739,P17900,P07602,Q06136,Q9NZ01,O95470,O15270,P04062 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 258,411,143,144,215,91,216,191 | 765,216,91,191,143,411,144,437,258,215 | 0.31709249325645056,1.2947503089070345,2.300644481221058,1.4372284667550546,1.7573792946827045,0.7515381995844014,1.7573792946827045,0.7087780760645422,1.1713983468947904,1.3151976269095578 | 3,329 |
Steroid biosynthetic process | 8 | 46 | 2.554166 | 0.010644 | Q16850,Q15125,P37268,P48449,Q15392,Q15800,P30536,Q14739 | Processes and pathways | GO Biological process | msigdb_gobp | 193,99,7,72,12,173,212,26 | 1022,1109,873,3058,845,3264,1586,2412,1991,1589,3084,1431,1788,2987,1658,212,7,2126,72,1733,1146,3137,1003,1488,437,3215,530,26,99,1807,12,1877,2575,2576,173,193,567,1127,2539,1448,3128,1969,2024,429,240,1406 | 0.1388221277863417,0.09382756959687372,0.22829447058781055,-0.8463621203281708,0.25055651741635415,-1.3760283681740184,-0.13382247009957884,-0.4368340474097858,-0.27264384148485665,-0.13382247009957884,-0.8709590302873479,-0.06504940216522562,-0.203017633379766,-0.7729219653555064,-0.156840189674286,1.3151976269095578,5.721954661682018,-0.3193053506689896,2.6581035741477934,-0.17990513363585875,0.07126469850274689,-0.9451070759599981,0.16125438838387834,-0.08792739806811385,0.7087780760645422,-1.1202684582751312,0.5796069942263014,3.908602733869772,2.2051248024821013,-0.203017633379766,4.796997022347357,-0.2261780242890793,-0.5079660590613365,-0.5079660590613365,1.578216255499028,1.4372284667550546,0.5362471404769038,0.09382756959687372,-0.4842032649662147,-0.06504940216522562,-0.9203310164531874,-0.24938664580266173,-0.27264384148485665,0.7301764410183317,1.2332184926667917,-0.04221734363056225 | 3,329 |
Exopeptidase activity | 14 | 32 | 2.548311 | 0.010825 | Q7Z2K6,O75844,P02786,Q92820,Q9UIQ6,Q9HB40,P42785,Q969V3,P55786,Q9NZ08,Q9H3G5,P10619,O75976,P09960 | Functions | GO Molecular function | msigdb_gomf | 455,131,477,428,13,78,17,340,242,87,89,88,254,434 | 842,131,254,477,434,88,2460,3150,2709,2418,17,2712,1734,794,242,3064,2960,455,515,428,340,2091,2636,717,89,1763,78,1017,2975,2695,87,13 | 0.25055651741635415,1.8165897720528055,1.1713983468947904,0.6443611882223067,0.7087780760645422,2.3196739353976064,-0.46049272408808617,-0.9699438469321776,-0.5795719264467128,-0.4368340474097858,4.400254146347629,-0.5795719264467128,-0.17990513363585875,0.2949552633600194,1.2126440410867516,-0.8463621203281708,-0.7485572109498702,0.6873428903362069,0.6012295760038491,0.7301764410183317,0.9211394780417321,-0.29594995909674393,-0.5317815003956151,0.3832587355956147,2.3196739353976064,-0.17990513363585875,2.5273994619272147,0.16125438838387834,-0.7485572109498702,-0.5556499880877578,2.3766152947125034,4.780639478907166 | 3,329 |
Lysosome | 17 | 47 | 2.538471 | 0.011134 | P50897,Q93050,P17900,Q99523,P20645,O15118,P07602,Q9UMR5,P07858,Q9Y487,O75503,Q8NCC3,P10619,P06280,Q13510,Q14108,P04062 | Processes and pathways | KEGG Pathways | msigdb_kegg | 128,164,411,138,365,400,143,176,336,149,54,85,88,460,437,156,191 | 2924,1067,2166,842,400,810,2285,54,191,791,460,1190,143,2822,336,656,1585,847,88,745,1314,657,2953,848,2557,411,365,3314,128,794,622,795,2471,1037,437,156,1747,85,164,138,1053,866,1909,2277,176,506,149 | -0.724249340547183,0.11634661657064145,-0.34271037257634035,0.25055651741635415,0.7728635640285376,0.27277669272882116,-0.38967075507457544,3.0073424154788886,1.4372284667550546,0.2949552633600194,0.6658706672953714,0.04865771165184635,1.7573792946827045,-0.6516625684987778,0.9211394780417321,0.4271675731360321,-0.13382247009957884,0.25055651741635415,2.3196739353976064,0.3391886435203106,-0.01943091003423015,0.4271675731360321,-0.7485572109498702,0.25055651741635415,-0.5079660590613365,0.7515381995844014,0.8578052533050858,-2.566124906447607,1.8755510915900018,0.2949552633600194,0.4709171468581955,0.2949552633600194,-0.46049272408808617,0.1388221277863417,0.7087780760645422,1.678038142292685,-0.17990513363585875,2.3955471029377042,1.6182320603396134,1.7968808074173586,0.1388221277863417,0.25055651741635415,-0.2261780242890793,-0.3661653856138045,1.55816439445645,0.6228142321842982,1.7177654379588205 | 3,329 |
Isomerase | 9 | 59 | 2.536941 | 0.011183 | P62942,P26885,Q15125,Q9Y680,Q96PZ0,P48449,Q02790,Q96AY3,Q9NWM8 | Functions | Protein Atlas Molecular function | protein_atlas_molecular_function | 0,34,99,170,9,72,83,21,183 | 2340,2650,2114,989,874,1923,1232,3099,2742,2823,2173,256,2602,2660,2290,34,3037,1479,2124,3061,2990,463,1999,72,1600,2902,0,1036,83,2570,2372,3173,182,2073,3215,2835,1085,2800,99,830,2573,3289,2019,3245,21,975,1250,1690,540,9,1057,606,2214,183,3181,448,1413,1515,170 | -0.41322685082973565,-0.5556499880877578,-0.3193053506689896,0.16125438838387834,0.22829447058781055,-0.24938664580266173,0.026006314080828572,-0.8956151662633678,-0.6035477250676271,-0.6516625684987778,-0.34271037257634035,1.1713983468947904,-0.5317815003956151,-0.5556499880877578,-0.38967075507457544,3.6835255876420354,-0.82182395495969,-0.08792739806811385,-0.3193053506689896,-0.8463621203281708,-0.7729219653555064,0.6658706672953714,-0.27264384148485665,2.6581035741477934,-0.13382247009957884,-0.6999979046598092,9.201100736968145,0.1388221277863417,2.4144547648383874,-0.5079660590613365,-0.41322685082973565,-1.0198015679513603,1.4978312091341666,-0.29594995909674393,-1.1202684582751312,-0.6516625684987778,0.11634661657064145,-0.6275777989300914,2.2051248024821013,0.27277669272882116,-0.5079660590613365,-1.6923152687852072,-0.27264384148485665,-1.2473063987901896,4.249159388964148,0.18364368033144304,0.026006314080828572,-0.156840189674286,0.5796069942263014,5.185270547408719,0.1388221277863417,0.4927328204863091,-0.34271037257634035,1.4978312091341666,-1.0198015679513603,0.7087780760645422,-0.04221734363056225,-0.08792739806811385,1.5982387622118392 | 3,329 |
transferase | 9 | 32 | 2.529896 | 0.01141 | O15217,Q9Y5P6,P43490,P37268,O43505,Q8NCH0,Q8NFF5,Q06203,O95674 | Functions | Panther Protein class | panther_protein_class | 2,332,5,7,171,146,419,354,255 | 3096,1416,2,171,2699,255,2657,2952,2413,2708,1192,1526,1660,1848,7,5,660,3253,1733,2930,354,426,146,419,942,1761,1823,1131,2850,675,2404,332 | -0.8956151662633678,-0.06504940216522562,7.076334795635697,1.578216255499028,-0.5795719264467128,1.1713983468947904,-0.5556499880877578,-0.7485572109498702,-0.4368340474097858,-0.5795719264467128,0.04865771165184635,-0.1108516474371695,-0.156840189674286,-0.2261780242890793,5.721954661682018,6.0461655933051235,0.4271675731360321,-1.2985888439224271,-0.17990513363585875,-0.724249340547183,0.8789517589290488,0.7301764410183317,1.7573792946827045,0.7515381995844014,0.2059902824751761,-0.17990513363585875,-0.203017633379766,0.09382756959687372,-0.6516625684987778,0.4271675731360321,-0.41322685082973565,0.9421810860656006 | 3,329 |
Steroid metabolism | 7 | 28 | 2.528209 | 0.011465 | Q16850,Q15125,P37268,Q15392,Q15800,Q14739,P04062 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 193,99,7,12,173,26,191 | 400,1109,873,3058,2455,191,2412,2987,960,7,1146,795,2672,3137,1003,1488,3215,26,99,1807,12,2576,173,193,668,3128,240,651 | 0.7728635640285376,0.09382756959687372,0.22829447058781055,-0.8463621203281708,-0.46049272408808617,1.4372284667550546,-0.4368340474097858,-0.7729219653555064,0.18364368033144304,5.721954661682018,0.07126469850274689,0.2949552633600194,-0.5556499880877578,-0.9451070759599981,0.16125438838387834,-0.08792739806811385,-1.1202684582751312,3.908602733869772,2.2051248024821013,-0.203017633379766,4.796997022347357,-0.5079660590613365,1.578216255499028,1.4372284667550546,0.4271675731360321,-0.9203310164531874,1.2332184926667917,0.4490621451928765 | 3,329 |
Sphingolipid metabolism | 11 | 25 | 2.513701 | 0.011947 | Q16739,P17900,Q96G23,P51648,P07602,Q06136,P10619,O95470,Q13510,O15270,P04062 | Processes and pathways | Reactome Pathways | msigdb_reactome | 258,411,165,392,143,144,88,91,437,216,191 | 2036,765,216,810,3131,91,191,460,1190,143,2822,88,2557,411,1431,392,144,437,258,165,2637,631,1831,866,1347 | -0.29594995909674393,0.31709249325645056,1.2947503089070345,0.27277669272882116,-0.9451070759599981,2.300644481221058,1.4372284667550546,0.6658706672953714,0.04865771165184635,1.7573792946827045,-0.6516625684987778,2.3196739353976064,-0.5079660590613365,0.7515381995844014,-0.06504940216522562,0.7941527445250331,1.7573792946827045,0.7087780760645422,1.1713983468947904,1.6182320603396134,-0.5317815003956151,0.4709171468581955,-0.203017633379766,0.25055651741635415,-0.01943091003423015 | 3,329 |
Mitochondrial respiratory chain complex assembly | 17 | 44 | 2.512073 | 0.012002 | Q9Y512,Q9BSK2,Q9H061,O43676,Q9Y2R0,Q15070,O95831,Q9Y6M9,Q96CU9,Q69YU5,O75306,Q8N4Q1,O75438,O95168,Q86Y39,Q6DKK2,O75880 | Processes and pathways | GO Biological process | msigdb_gobp | 488,66,260,163,134,200,105,475,142,48,234,50,403,404,377,186,311 | 1710,163,2045,3240,234,403,1716,311,844,404,1722,105,2498,2821,3161,642,1197,3274,1543,200,1879,1289,48,186,1090,377,586,518,50,2201,142,861,756,66,3158,260,2213,1063,782,1346,3145,134,488,475 | -0.17990513363585875,1.6381962943967536,-0.29594995909674393,-1.2473063987901896,1.2332184926667917,0.7728635640285376,-0.17990513363585875,0.9631881196187747,0.25055651741635415,0.7728635640285376,-0.17990513363585875,2.1089741942010813,-0.4842032649662147,-0.6516625684987778,-0.9948418387058783,0.4490621451928765,0.04865771165184635,-1.4280060568502317,-0.1108516474371695,1.4169669380234817,-0.2261780242890793,0.0033102074454991735,3.2239578076854247,1.47766044819358,0.11634661657064145,0.8366233840884401,0.5145094059098909,0.6012295760038491,3.1340610333831447,-0.34271037257634035,1.777144026318633,0.25055651741635415,0.3391886435203106,2.7692470748533924,-0.9699438469321776,1.1713983468947904,-0.34271037257634035,0.1388221277863417,0.31709249325645056,-0.01943091003423015,-0.9451070759599981,1.8165897720528055,0.6443611882223067,0.6658706672953714 | 3,329 |
Isomerase activity | 9 | 70 | 2.509244 | 0.012099 | P62942,P26885,Q15125,Q9Y680,Q96PZ0,P48449,Q02790,Q96AY3,Q9NWM8 | Functions | GO Molecular function | msigdb_gomf | 0,34,99,170,9,72,83,21,183 | 3055,2340,2650,2114,989,874,1923,1232,3099,2742,2823,2173,256,2602,2660,2290,34,1527,1269,3037,1479,2124,3061,2990,463,1999,2511,72,2128,1600,2902,0,1036,83,2570,2372,3173,182,2073,3215,2835,1085,2800,99,830,2573,1045,1295,1886,3289,2019,3245,2807,21,975,1250,1690,540,9,1894,1057,606,2214,183,3181,1916,448,1413,1515,170 | -0.8463621203281708,-0.41322685082973565,-0.5556499880877578,-0.3193053506689896,0.16125438838387834,0.22829447058781055,-0.24938664580266173,0.026006314080828572,-0.8956151662633678,-0.6035477250676271,-0.6516625684987778,-0.34271037257634035,1.1713983468947904,-0.5317815003956151,-0.5556499880877578,-0.38967075507457544,3.6835255876420354,-0.1108516474371695,0.0033102074454991735,-0.82182395495969,-0.08792739806811385,-0.3193053506689896,-0.8463621203281708,-0.7729219653555064,0.6658706672953714,-0.27264384148485665,-0.4842032649662147,2.6581035741477934,-0.3193053506689896,-0.13382247009957884,-0.6999979046598092,9.201100736968145,0.1388221277863417,2.4144547648383874,-0.5079660590613365,-0.41322685082973565,-1.0198015679513603,1.4978312091341666,-0.29594995909674393,-1.1202684582751312,-0.6516625684987778,0.11634661657064145,-0.6275777989300914,2.2051248024821013,0.27277669272882116,-0.5079660590613365,0.1388221277863417,0.0033102074454991735,-0.2261780242890793,-1.6923152687852072,-0.27264384148485665,-1.2473063987901896,-0.6275777989300914,4.249159388964148,0.18364368033144304,0.026006314080828572,-0.156840189674286,0.5796069942263014,5.185270547408719,-0.2261780242890793,0.1388221277863417,0.4927328204863091,-0.34271037257634035,1.4978312091341666,-1.0198015679513603,-0.2261780242890793,0.7087780760645422,-0.04221734363056225,-0.08792739806811385,1.5982387622118392 | 3,329 |
Steroid metabolic process | 12 | 70 | 2.506175 | 0.012205 | Q16850,Q15125,P37268,P48449,P38435,Q15392,Q15800,Q8WTV0,P30536,Q14739,O95470,P04062 | Processes and pathways | GO Biological process | msigdb_gobp | 193,99,7,72,229,12,173,14,212,26,91,191 | 1022,400,1109,873,91,3058,2455,191,845,3264,3290,1586,2412,1991,1589,3084,1431,1788,2987,2988,1658,212,3134,960,7,229,3314,2126,72,2422,2514,1600,1733,1146,795,2672,3137,1003,1241,1488,437,3215,530,26,1876,99,1807,12,1877,2575,2576,173,193,567,668,2578,1127,14,2539,1448,3128,1895,1969,2024,429,1345,240,651,1406,1459 | 0.1388221277863417,0.7728635640285376,0.09382756959687372,0.22829447058781055,2.300644481221058,-0.8463621203281708,-0.46049272408808617,1.4372284667550546,0.25055651741635415,-1.3760283681740184,-1.7191687868793748,-0.13382247009957884,-0.4368340474097858,-0.27264384148485665,-0.13382247009957884,-0.8709590302873479,-0.06504940216522562,-0.203017633379766,-0.7729219653555064,-0.7729219653555064,-0.156840189674286,1.3151976269095578,-0.9451070759599981,0.18364368033144304,5.721954661682018,1.253760908657221,-2.566124906447607,-0.3193053506689896,2.6581035741477934,-0.4368340474097858,-0.4842032649662147,-0.13382247009957884,-0.17990513363585875,0.07126469850274689,0.2949552633600194,-0.5556499880877578,-0.9451070759599981,0.16125438838387834,0.026006314080828572,-0.08792739806811385,0.7087780760645422,-1.1202684582751312,0.5796069942263014,3.908602733869772,-0.2261780242890793,2.2051248024821013,-0.203017633379766,4.796997022347357,-0.2261780242890793,-0.5079660590613365,-0.5079660590613365,1.578216255499028,1.4372284667550546,0.5362471404769038,0.4271675731360321,-0.5079660590613365,0.09382756959687372,4.747880134126402,-0.4842032649662147,-0.06504940216522562,-0.9203310164531874,-0.2261780242890793,-0.24938664580266173,-0.27264384148485665,0.7301764410183317,-0.01943091003423015,1.2332184926667917,0.4490621451928765,-0.04221734363056225,-0.06504940216522562 | 3,329 |
Reductase | 7 | 17 | 2.502414 | 0.012335 | P00374,Q9UBM7,Q15392,Q9UDW1,O95881,Q14739,Q7LG56 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 41,240,12,175,305,26,189 | 2819,404,305,41,3034,815,1991,2355,1362,725,26,12,189,2479,606,240,175 | -0.6516625684987778,0.7728635640285376,0.9841607712980948,3.4022527556665043,-0.82182395495969,0.27277669272882116,-0.27264384148485665,-0.41322685082973565,-0.04221734363056225,0.3612439724526373,3.908602733869772,4.796997022347357,1.457459585216246,-0.46049272408808617,0.4927328204863091,1.2332184926667917,1.55816439445645 | 3,329 |
Transporter activity | 50 | 166 | 2.501329 | 0.012373 | Q9UBX3,P12235,Q9HD20,Q8WTV0,Q9NS69,Q9NQ11,O15118,O75438,O95168,Q9Y487,P00846,Q96S66,Q70HW3,P53985,Q99595,O43676,Q93050,P17900,Q9Y619,Q9H4L5,O43772,Q9UDW1,Q6NT16,P41440,P04062,P21796,P08183,Q9BSK2,P45880,Q8IXU6,Q9H2D1,Q9Y6M9,P30536,Q9HC07,O95563,Q7KZN9,P51991,P20674,O75964,Q02978,P38435,Q96QD8,Q9H813,Q03518,O75306,O14925,O15173,Q6P4A7,Q00535,Q01469 | Functions | GO Molecular function | msigdb_gomf | 398,266,140,14,16,275,400,403,404,149,24,284,27,413,35,163,164,411,39,429,44,175,49,55,191,64,433,66,67,68,69,475,212,222,93,483,352,351,104,106,229,370,504,110,234,241,114,376,495,375 | 1772,1710,2925,2039,915,2947,241,400,114,2817,163,810,44,1024,2652,3240,234,680,403,1716,1718,919,104,2168,2951,844,404,1837,790,1722,93,2498,1782,3302,24,2821,191,845,1784,846,2228,2350,3264,2706,433,1584,1074,616,1651,266,1265,1471,490,411,2984,1076,351,816,3149,64,1431,748,3085,1658,3161,212,769,1077,1029,229,2239,55,67,642,2956,820,793,3172,661,1197,352,1601,1664,413,727,884,1276,3274,1541,795,2520,1002,495,375,106,110,1149,1281,796,2932,1121,1204,1613,1375,1879,1289,1327,49,585,2137,376,27,483,600,68,715,1211,2582,1047,2583,1816,14,3164,164,539,587,370,284,1448,1449,35,570,717,66,2970,2323,1896,1055,1971,69,946,3192,429,504,1901,1828,222,140,275,16,1906,1346,398,175,783,1909,652,1637,2488,870,149,1103,1834,39,2164,475 | -0.203017633379766,-0.17990513363585875,-0.724249340547183,-0.29594995909674393,0.2059902824751761,-0.7485572109498702,1.2126440410867516,0.7728635640285376,1.9732758301648015,-0.6516625684987778,1.6381962943967536,0.27277669272882116,3.33117123497569,0.1388221277863417,-0.5556499880877578,-1.2473063987901896,1.2332184926667917,0.40523318577404505,0.7728635640285376,-0.17990513363585875,-0.17990513363585875,0.2059902824751761,2.1089741942010813,-0.34271037257634035,-0.7485572109498702,0.25055651741635415,0.7728635640285376,-0.2261780242890793,0.2949552633600194,-0.17990513363585875,2.262511421655104,-0.4842032649662147,-0.203017633379766,-1.9922392137678377,4.04563696990221,-0.6516625684987778,1.4372284667550546,0.25055651741635415,-0.203017633379766,0.25055651741635415,-0.3661653856138045,-0.41322685082973565,-1.3760283681740184,-0.5795719264467128,0.7087780760645422,-0.13382247009957884,0.11634661657064145,0.4709171468581955,-0.156840189674286,1.1092852207351331,0.0033102074454991735,-0.08792739806811385,0.6228142321842982,0.7515381995844014,-0.7729219653555064,0.11634661657064145,0.8789517589290488,0.27277669272882116,-0.9699438469321776,2.824517962466285,-0.06504940216522562,0.3391886435203106,-0.8709590302873479,-0.156840189674286,-0.9948418387058783,1.3151976269095578,0.31709249325645056,0.11634661657064145,0.1388221277863417,1.253760908657221,-0.3661653856138045,3.0073424154788886,2.750779178310562,0.4490621451928765,-0.7485572109498702,0.27277669272882116,0.2949552633600194,-1.0198015679513603,0.4271675731360321,0.04865771165184635,0.8789517589290488,-0.13382247009957884,-0.156840189674286,0.7515381995844014,0.3612439724526373,0.22829447058781055,0.0033102074454991735,-1.4280060568502317,-0.1108516474371695,0.2949552633600194,-0.4842032649662147,0.16125438838387834,0.6228142321842982,0.8366233840884401,2.089667102484907,2.0509750105284508,0.07126469850274689,0.0033102074454991735,0.2949552633600194,-0.724249340547183,0.09382756959687372,0.04865771165184635,-0.13382247009957884,-0.04221734363056225,-0.2261780242890793,0.0033102074454991735,-0.01943091003423015,3.2060189747398833,0.5145094059098909,-0.3193053506689896,0.8366233840884401,3.908602733869772,0.6443611882223067,0.4927328204863091,2.7322889967086703,0.3832587355956147,0.04865771165184635,-0.5079660590613365,0.1388221277863417,-0.5079660590613365,-0.203017633379766,4.747880134126402,-0.9948418387058783,1.6182320603396134,0.5796069942263014,0.5145094059098909,0.8578052533050858,1.0677113479047518,-0.06504940216522562,-0.06504940216522562,3.64862783763913,0.5362471404769038,0.3832587355956147,2.7692470748533924,-0.7485572109498702,-0.38967075507457544,-0.2261780242890793,0.1388221277863417,-0.24938664580266173,2.7322889967086703,0.2059902824751761,-1.0448235588232042,0.7301764410183317,0.6228142321842982,-0.2261780242890793,-0.203017633379766,1.2947503089070345,1.7968808074173586,1.0885149161930745,4.533482019529468,-0.2261780242890793,-0.01943091003423015,0.7941527445250331,1.55816439445645,0.31709249325645056,-0.2261780242890793,0.4490621451928765,-0.13382247009957884,-0.46049272408808617,0.25055651741635415,1.7177654379588205,0.11634661657064145,-0.203017633379766,3.52590265888114,-0.3193053506689896,0.6658706672953714 | 3,329 |
ER-Golgi transport | 10 | 50 | 2.496925 | 0.012528 | Q9Y282,Q9P2W9,P18085,O95197,O43731,Q15363,Q8IUR0,P84085,P24390,P49257 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 97,233,292,135,19,115,315,344,30,220 | 1068,350,788,1642,19,1421,1781,1921,592,135,1424,292,1430,30,959,2179,220,793,2181,2613,2563,2515,2468,1538,1034,2365,344,2571,1546,115,1087,2434,1290,3041,315,1684,2202,444,2320,1214,2687,1342,1630,1401,233,2217,97,1222,2856,1709 | 0.11634661657064145,0.8789517589290488,0.2949552633600194,-0.156840189674286,4.266012245132118,-0.06504940216522562,-0.203017633379766,-0.24938664580266173,0.4927328204863091,1.7968808074173586,-0.06504940216522562,1.0468743338568534,-0.06504940216522562,3.8223910414490736,0.18364368033144304,-0.34271037257634035,1.2947503089070345,0.2949552633600194,-0.34271037257634035,-0.5317815003956151,-0.5079660590613365,-0.4842032649662147,-0.46049272408808617,-0.1108516474371695,0.1388221277863417,-0.41322685082973565,0.900063101102262,-0.5079660590613365,-0.1108516474371695,1.9732758301648015,0.11634661657064145,-0.4368340474097858,0.0033102074454991735,-0.82182395495969,0.9631881196187747,-0.156840189674286,-0.34271037257634035,0.7087780760645422,-0.38967075507457544,0.04865771165184635,-0.5556499880877578,-0.01943091003423015,-0.13382247009957884,-0.04221734363056225,1.253760908657221,-0.34271037257634035,2.243407596862186,0.04865771165184635,-0.6516625684987778,-0.156840189674286 | 3,329 |
Subcutaneous nodule | 8 | 19 | 2.484363 | 0.012978 | Q9NSE4,O75874,P31749,P48735,Q9NZ08,P49327,Q13510,P35637 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 265,76,209,22,87,342,437,127 | 76,614,460,746,1525,703,209,2059,127,22,342,1598,883,2430,1858,437,265,87,3095 | 2.546140982982583,0.4709171468581955,0.6658706672953714,0.3391886435203106,-0.1108516474371695,0.3832587355956147,1.3356135768468178,-0.29594995909674393,1.8755510915900018,4.1646493114890495,0.900063101102262,-0.13382247009957884,0.22829447058781055,-0.4368340474097858,-0.2261780242890793,0.7087780760645422,1.1300224418606861,2.3766152947125034,-0.8709590302873479 | 3,329 |
Glutathione metabolism | 6 | 24 | 2.482374 | 0.013051 | O15217,P78417,Q9UJ14,O75874,P48735,Q7LG56 | Processes and pathways | KEGG Pathways | msigdb_kegg | 2,198,133,76,22,189 | 1416,2,2650,1919,76,305,1922,1586,2413,2708,2355,1526,3150,725,2062,2609,22,2793,2992,198,189,1761,133,2404 | -0.06504940216522562,7.076334795635697,-0.5556499880877578,-0.24938664580266173,2.546140982982583,0.9841607712980948,-0.24938664580266173,-0.13382247009957884,-0.4368340474097858,-0.5795719264467128,-0.41322685082973565,-0.1108516474371695,-0.9699438469321776,0.3612439724526373,-0.29594995909674393,-0.5317815003956151,4.1646493114890495,-0.6275777989300914,-0.7729219653555064,1.4169669380234817,1.457459585216246,-0.17990513363585875,1.8165897720528055,-0.41322685082973565 | 3,329 |
Golgi associated vesicle | 7 | 31 | 2.480485 | 0.01312 | Q8N511,Q8TCT8,Q99523,O43731,Q15363,P42356,P24390 | Localization | GO Cellular component | msigdb_gocc | 327,71,138,19,115,219,30 | 1068,19,2285,2347,1585,657,30,959,219,2179,793,1271,2613,2563,3062,1277,1034,2471,2430,115,327,71,2202,1758,138,329,1132,1019,2217,2033,2856 | 0.11634661657064145,4.266012245132118,-0.38967075507457544,-0.41322685082973565,-0.13382247009957884,0.4271675731360321,3.8223910414490736,0.18364368033144304,1.2947503089070345,-0.34271037257634035,0.2949552633600194,0.0033102074454991735,-0.5317815003956151,-0.5079660590613365,-0.8463621203281708,0.0033102074454991735,0.1388221277863417,-0.46049272408808617,-0.4368340474097858,1.9732758301648015,0.9421810860656006,2.713776438256748,-0.34271037257634035,-0.17990513363585875,1.7968808074173586,0.9421810860656006,0.09382756959687372,0.16125438838387834,-0.34271037257634035,-0.27264384148485665,-0.6516625684987778 | 3,329 |
er | 28 | 86 | 2.466069 | 0.013661 | Q9H6H4,O96005,Q15392,Q06136,Q9Y487,Q14739,O00264,Q07065,P18085,Q969Q5,Q6NUK4,Q16850,Q15041,P48449,Q969V3,P09132,Q8NHH9,O95470,P84085,O15270,O75340,Q15125,Q9P2W9,Q96A33,O15173,Q15363,Q9Y5M8,O95674 | Localization | OpenCell Localization | opencell_localization | 521,381,12,144,149,26,524,161,292,569,440,193,199,72,340,461,601,91,344,216,459,99,233,626,114,115,523,255 | 524,3009,3096,114,765,216,2167,459,1781,2454,3131,91,255,381,1230,3058,1425,2349,2172,461,292,2234,1361,2510,1079,72,660,793,1599,1271,2181,2361,1665,3017,1538,2130,3295,344,1001,1673,144,161,964,2571,26,3065,199,99,115,12,2576,1325,193,1617,440,2137,2262,1621,715,2088,1247,1159,601,1686,3157,2202,1758,569,340,626,650,2637,1896,521,1306,1099,1401,1133,1976,1347,233,1637,1770,149,523,1709 | 0.5796069942263014,-0.7973440593945568,-0.8956151662633678,1.9732758301648015,0.31709249325645056,1.2947503089070345,-0.34271037257634035,0.6658706672953714,-0.203017633379766,-0.46049272408808617,-0.9451070759599981,2.300644481221058,1.1713983468947904,0.815405949185715,0.026006314080828572,-0.8463621203281708,-0.06504940216522562,-0.41322685082973565,-0.34271037257634035,0.6658706672953714,1.0468743338568534,-0.3661653856138045,-0.04221734363056225,-0.4842032649662147,0.11634661657064145,2.6581035741477934,0.4271675731360321,0.2949552633600194,-0.13382247009957884,0.0033102074454991735,-0.34271037257634035,-0.41322685082973565,-0.156840189674286,-0.7973440593945568,-0.1108516474371695,-0.3193053506689896,-1.8273903232840274,0.900063101102262,0.16125438838387834,-0.156840189674286,1.7573792946827045,1.6581316076819692,0.18364368033144304,-0.5079660590613365,3.908602733869772,-0.8463621203281708,1.4169669380234817,2.2051248024821013,1.9732758301648015,4.796997022347357,-0.5079660590613365,-0.01943091003423015,1.4372284667550546,-0.13382247009957884,0.7087780760645422,-0.3193053506689896,-0.3661653856138045,-0.13382247009957884,0.3832587355956147,-0.29594995909674393,0.026006314080828572,0.07126469850274689,0.4927328204863091,-0.156840189674286,-0.9699438469321776,-0.34271037257634035,-0.17990513363585875,0.5362471404769038,0.9211394780417321,0.4709171468581955,0.4490621451928765,-0.5317815003956151,-0.2261780242890793,0.6012295760038491,0.0033102074454991735,0.11634661657064145,-0.04221734363056225,0.09382756959687372,-0.24938664580266173,-0.01943091003423015,1.253760908657221,-0.13382247009957884,-0.17990513363585875,1.7177654379588205,0.6012295760038491,-0.156840189674286 | 3,329 |
Endoplasmic reticulum golgi intermediate compartment membrane | 6 | 26 | 2.459402 | 0.013917 | Q8N511,Q9Y282,Q03518,Q15363,P49257,P24390 | Localization | GO Cellular component | msigdb_gocc | 327,97,110,115,220,30 | 788,1781,592,30,681,2461,220,793,2181,794,1538,110,887,1369,710,115,1747,327,2320,1214,329,758,1825,97,1461,2033 | 0.2949552633600194,-0.203017633379766,0.4927328204863091,3.8223910414490736,0.40523318577404505,-0.46049272408808617,1.2947503089070345,0.2949552633600194,-0.34271037257634035,0.2949552633600194,-0.1108516474371695,2.0509750105284508,0.22829447058781055,-0.04221734363056225,0.3832587355956147,1.9732758301648015,-0.17990513363585875,0.9421810860656006,-0.38967075507457544,0.04865771165184635,0.9421810860656006,0.3391886435203106,-0.203017633379766,2.243407596862186,-0.06504940216522562,-0.27264384148485665 | 3,329 |
Abnormality of femur morphology | 19 | 70 | 2.454568 | 0.014105 | O75844,O15360,P07602,Q96AY3,Q9Y487,Q14739,Q7RTS9,Q32P28,Q9Y619,Q7LGA3,Q9UHX1,O43909,P04062,O95613,O75718,P06280,O95831,Q99575,P28482 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 131,401,143,21,149,26,28,37,39,426,318,185,191,452,335,460,105,503,374 | 575,2697,2926,1067,2551,401,185,843,2860,988,335,131,2227,452,105,1230,2656,191,791,2411,460,143,509,2557,1589,2743,2232,374,1531,2606,995,2666,2179,822,1437,1853,727,3017,26,2374,2755,37,3068,1290,2841,426,28,3071,1247,3163,2843,626,21,2204,2144,503,1013,1216,779,2974,1973,950,3003,866,318,1410,2032,149,1708,39 | 0.5145094059098909,-0.5795719264467128,-0.724249340547183,0.11634661657064145,-0.5079660590613365,0.7728635640285376,1.47766044819358,0.25055651741635415,-0.6758024598264976,0.16125438838387834,0.9211394780417321,1.8165897720528055,-0.3661653856138045,0.6873428903362069,2.1089741942010813,0.026006314080828572,-0.5556499880877578,1.4372284667550546,0.2949552633600194,-0.4368340474097858,0.6658706672953714,1.7573792946827045,0.6012295760038491,-0.5079660590613365,-0.13382247009957884,-0.6035477250676271,-0.3661653856138045,0.8366233840884401,-0.1108516474371695,-0.5317815003956151,0.16125438838387834,-0.5556499880877578,-0.34271037257634035,0.27277669272882116,-0.06504940216522562,-0.2261780242890793,0.3612439724526373,-0.7973440593945568,3.908602733869772,-0.41322685082973565,-0.6035477250676271,3.596143058067744,-0.8463621203281708,0.0033102074454991735,-0.6516625684987778,0.7301764410183317,3.874170839925339,-0.8463621203281708,0.026006314080828572,-0.9948418387058783,-0.6516625684987778,0.4709171468581955,4.249159388964148,-0.34271037257634035,-0.3193053506689896,0.6228142321842982,0.16125438838387834,0.04865771165184635,0.31709249325645056,-0.7485572109498702,-0.24938664580266173,0.2059902824751761,-0.7729219653555064,0.25055651741635415,0.9631881196187747,-0.04221734363056225,-0.27264384148485665,1.7177654379588205,-0.156840189674286,3.52590265888114 | 3,329 |
metalloprotease | 12 | 26 | 2.453895 | 0.014132 | Q7Z2K6,O75844,P02786,O95630,Q9UIQ6,P42892,P55786,Q96TA2,Q9NZ08,Q99797,Q9BYT8,Q5JRX3 | Functions | Panther Protein class | panther_protein_class | 455,131,477,576,13,82,242,467,87,570,345,124 | 2286,1987,131,576,477,2460,1473,1593,3150,769,82,621,1734,242,888,124,455,2636,467,570,345,1017,2695,87,13,1513 | -0.38967075507457544,-0.27264384148485665,1.8165897720528055,0.5145094059098909,0.6443611882223067,-0.46049272408808617,-0.08792739806811385,-0.13382247009957884,-0.9699438469321776,0.31709249325645056,2.452198066890038,0.4709171468581955,-0.17990513363585875,1.2126440410867516,0.22829447058781055,1.8951501094270817,0.6873428903362069,-0.5317815003956151,0.6658706672953714,0.5362471404769038,0.900063101102262,0.16125438838387834,-0.5556499880877578,2.3766152947125034,4.780639478907166,-0.08792739806811385 | 3,329 |
Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen | 11 | 33 | 2.439249 | 0.014718 | Q9BU89,Q16850,Q32P28,Q8NB78,P13674,P30519,Q15800,P09601,Q9H6W3,O15460,Q9NVH6 | Functions | GO Molecular function | msigdb_gomf | 389,193,37,251,201,11,173,53,153,247,126 | 2926,3009,247,679,843,380,3147,1232,53,201,1589,11,3018,1739,1370,1442,530,173,193,37,3070,933,690,2805,1753,251,389,1253,3236,153,126,1979,3006 | -0.724249340547183,-0.7973440593945568,1.1920373832406677,0.40523318577404505,0.25055651741635415,0.815405949185715,-0.9699438469321776,0.026006314080828572,3.025507611654335,1.396674842878999,-0.13382247009957884,4.959771689307768,-0.7973440593945568,-0.17990513363585875,-0.04221734363056225,-0.06504940216522562,0.5796069942263014,1.578216255499028,1.4372284667550546,3.596143058067744,-0.8463621203281708,0.2059902824751761,0.40523318577404505,-0.6275777989300914,-0.17990513363585875,1.1920373832406677,0.815405949185715,0.026006314080828572,-1.1962933336355144,1.6979160391392325,1.8951501094270817,-0.24938664580266173,-0.7729219653555064 | 3,329 |
Abnormal muscle fiber morphology | 25 | 73 | 2.424509 | 0.015329 | P46976,P11047,P12235,P00846,Q70HW3,O43676,Q9BUK6,O75648,P61978,P07196,Q7LG56,P51114,Q99720,Q9Y5P6,Q9H2D1,Q8NI60,Q06210,P22626,P23786,O14979,P09651,O75340,O60313,O95831,P35637 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 512,261,266,24,27,163,294,410,414,306,189,313,194,332,69,328,323,202,77,207,462,459,217,105,127 | 2039,207,163,1779,217,459,410,105,1782,3302,24,2656,2821,3011,593,306,2289,462,261,266,876,2986,202,77,1844,994,1594,127,2746,1115,512,528,961,313,1664,1853,2361,414,1739,323,2572,1202,2074,2527,2530,1809,27,189,3041,972,2198,1624,3269,328,1955,753,3298,2810,194,2727,2265,2484,294,1254,69,3179,2151,1916,3145,1917,1513,1351,332 | -0.29594995909674393,1.3559983218997487,1.6381962943967536,-0.203017633379766,1.2947503089070345,0.6658706672953714,0.7515381995844014,2.1089741942010813,-0.203017633379766,-1.9922392137678377,4.04563696990221,-0.5556499880877578,-0.6516625684987778,-0.7973440593945568,0.4927328204863091,0.9841607712980948,-0.38967075507457544,0.6658706672953714,1.1507267582378766,1.1092852207351331,0.22829447058781055,-0.7729219653555064,1.396674842878999,2.546140982982583,-0.2261780242890793,0.16125438838387834,-0.13382247009957884,1.8755510915900018,-0.6035477250676271,0.09382756959687372,0.6012295760038491,0.5796069942263014,0.18364368033144304,0.9631881196187747,-0.156840189674286,-0.2261780242890793,-0.41322685082973565,0.7515381995844014,-0.17990513363585875,0.9421810860656006,-0.5079660590613365,0.04865771165184635,-0.29594995909674393,-0.4842032649662147,-0.4842032649662147,-0.203017633379766,3.908602733869772,1.457459585216246,-0.82182395495969,0.18364368033144304,-0.34271037257634035,-0.13382247009957884,-1.3760283681740184,0.9421810860656006,-0.24938664580266173,0.3391886435203106,-1.8546517595200398,-0.6275777989300914,1.4372284667550546,-0.5795719264467128,-0.3661653856138045,-0.46049272408808617,1.0468743338568534,0.026006314080828572,2.7322889967086703,-1.0198015679513603,-0.3193053506689896,-0.2261780242890793,-0.9451070759599981,-0.2261780242890793,-0.08792739806811385,-0.01943091003423015,0.9421810860656006 | 3,329 |
primary active transporter | 7 | 22 | 2.408363 | 0.016024 | Q9BUN8,P09132,P16615,Q9NS69,Q6P4A7,O60888,Q8N4H5 | Functions | Panther Protein class | panther_protein_class | 468,461,490,16,376,25,92 | 25,2343,2168,1782,845,1784,461,2659,490,1076,2246,1613,1375,376,92,587,468,946,1828,1396,16,1414 | 4.011481464176911,-0.41322685082973565,-0.34271037257634035,-0.203017633379766,0.25055651741635415,-0.203017633379766,0.6658706672953714,-0.5556499880877578,0.6228142321842982,0.11634661657064145,-0.3661653856138045,-0.13382247009957884,-0.04221734363056225,0.8366233840884401,2.2815903464027634,0.5145094059098909,0.6658706672953714,0.2059902824751761,-0.203017633379766,-0.04221734363056225,4.533482019529468,-0.04221734363056225 | 3,329 |
Retrograde vesicle mediated transport golgi to endoplasmic reticulum | 7 | 32 | 2.40022 | 0.016385 | Q9Y282,Q9P2W9,P18085,P42858,O43731,Q96JB2,P24390 | Processes and pathways | GO Biological process | msigdb_gobp | 97,233,292,296,19,252,30 | 2223,1068,1355,19,1781,292,1430,30,959,296,2179,820,793,2563,1034,2616,344,710,2571,1290,716,2202,938,2320,252,1214,905,589,779,233,2217,97 | -0.3661653856138045,0.11634661657064145,-0.04221734363056225,4.266012245132118,-0.203017633379766,1.0468743338568534,-0.06504940216522562,3.8223910414490736,0.18364368033144304,1.0260036903302046,-0.34271037257634035,0.27277669272882116,0.2949552633600194,-0.5079660590613365,0.1388221277863417,-0.5317815003956151,0.900063101102262,0.3832587355956147,-0.5079660590613365,0.0033102074454991735,0.3832587355956147,-0.34271037257634035,0.2059902824751761,-0.38967075507457544,1.1920373832406677,0.04865771165184635,0.22829447058781055,0.5145094059098909,0.31709249325645056,1.253760908657221,-0.34271037257634035,2.243407596862186 | 3,329 |
Nuclear outer membrane endoplasmic reticulum membrane network | 83 | 301 | 2.391721 | 0.01677 | P62942,Q9H6H4,P37268,P30519,Q15392,Q96JJ7,Q5BJF2,O43731,O94888,Q04323,Q14739,P50402,P24390,O00264,Q14534,P26885,P09601,O60725,Q8TCT8,P48449,Q15629,Q9NZ08,O95470,Q8N2K0,P07099,Q9Y282,Q15125,Q16799,Q86XL3,Q03518,Q15363,P43307,O75844,O95197,Q99523,Q9HD20,Q06136,Q14108,Q07065,Q96G23,Q15800,O43909,Q16850,Q99720,Q15041,Q9BRR6,Q9NZ01,P49257,Q9BU23,O15270,P35613,Q9P2W9,P38435,Q9UBM7,Q8N0U8,O95674,Q86YN1,Q8IV08,Q96S66,P10321,Q5VV42,Q8N511,P62857,Q9BVK6,P67812,Q969V3,O15027,Q8N5M9,Q9P035,P51648,O43852,A1L0T0,Q9H4L5,Q8N2F6,Q6NUK4,Q7Z2K6,Q96PC5,Q9BUN8,Q9Y2B2,Q9UBF8,O75340,P16615,Q9Y5M8 | Localization | GO Cellular component | msigdb_gocc | 0,521,7,11,12,540,18,19,20,529,26,528,30,524,530,34,53,56,71,72,74,87,91,94,96,97,99,102,107,110,115,117,131,135,138,140,144,156,161,165,173,185,193,194,199,213,215,220,221,216,218,233,229,240,244,255,264,269,284,291,308,327,320,329,339,340,350,378,397,392,391,409,429,442,440,455,456,468,474,473,459,490,523 | 2036,409,2223,524,740,2926,2550,3009,1068,3096,1416,987,1138,350,765,216,1642,2167,19,391,1466,185,2452,843,56,1310,1187,459,1781,1109,1422,131,2454,744,1228,20,873,1921,592,135,3131,91,1424,1649,255,2497,1230,3058,2499,614,615,1425,2349,1427,3132,96,2172,3012,53,291,1360,1589,490,1725,641,1430,1431,2986,30,34,2461,1361,2955,3037,11,922,1318,1792,959,960,218,7,229,2510,1195,2420,117,1079,2179,72,660,820,220,1933,793,2128,528,1599,1798,2181,392,1799,997,2613,2563,2515,2361,565,1665,851,1937,1538,2130,1277,2614,1540,1541,3295,1034,1670,320,0,1081,1199,339,885,1001,1739,2674,110,529,144,161,1149,709,1369,1370,710,2571,1868,712,156,666,2835,530,1085,26,1677,3065,199,1943,2800,99,115,2135,12,1087,74,2576,173,1747,102,193,567,18,1244,2434,308,1617,2378,440,1290,1089,2137,598,455,600,1009,1551,107,1621,264,1949,269,1951,3045,244,442,94,715,327,1884,378,2088,2384,2842,1159,3269,2759,601,1756,3072,1816,857,1686,1955,71,3127,716,2141,2202,753,1818,899,2807,1556,778,340,2320,626,2483,1759,165,1760,2204,540,628,650,456,3298,1214,1558,284,1499,138,194,1761,213,1894,2637,757,1895,221,468,556,2970,329,1896,3219,1971,1825,1972,836,429,521,2813,1256,1342,140,1306,2850,2915,1099,2329,1133,1345,3246,1831,215,87,397,1976,1347,2027,233,2217,473,240,698,1907,783,1257,2159,1637,3115,97,474,984,1412,1461,2033,2110,3220,1351,523,1570,1224,2856,1104,1709,2035 | 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| 3,329 |
Abnormal circulating lipid concentration | 17 | 80 | 2.387573 | 0.01696 | P28070,Q15125,O75844,P37268,P42858,Q16836,Q8IWV7,Q9UBM7,Q15392,P23786,O43772,Q15800,P07602,P49257,Q14739,O95470,O75880 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 129,99,131,7,296,137,168,240,12,77,44,173,143,220,26,91,311 | 2551,956,1643,44,2343,988,410,131,311,91,2455,2656,460,1313,143,1924,3313,1268,77,129,2603,3134,3087,2463,2464,7,3314,879,880,296,492,220,2422,528,1237,822,2668,1600,2516,2713,998,795,2428,2430,1120,709,826,1202,26,552,99,12,2576,173,2906,1747,137,2529,668,2909,168,327,3269,3189,753,444,778,1334,2484,2213,779,1018,866,240,2029,652,2337,3220,1351,1709 | -0.5079660590613365,0.18364368033144304,-0.156840189674286,3.33117123497569,-0.41322685082973565,0.16125438838387834,0.7515381995844014,1.8165897720528055,0.9631881196187747,2.300644481221058,-0.46049272408808617,-0.5556499880877578,0.6658706672953714,-0.01943091003423015,1.7573792946827045,-0.24938664580266173,-2.566124906447607,0.0033102074454991735,2.546140982982583,1.8362710532052997,-0.5317815003956151,-0.9451070759599981,-0.8709590302873479,-0.46049272408808617,-0.46049272408808617,5.721954661682018,-2.566124906447607,0.22829447058781055,0.22829447058781055,1.0260036903302046,0.6228142321842982,1.2947503089070345,-0.4368340474097858,0.5796069942263014,0.026006314080828572,0.27277669272882116,-0.5556499880877578,-0.13382247009957884,-0.4842032649662147,-0.5795719264467128,0.16125438838387834,0.2949552633600194,-0.4368340474097858,-0.4368340474097858,0.09382756959687372,0.3832587355956147,0.27277669272882116,0.04865771165184635,3.908602733869772,0.5579462590868453,2.2051248024821013,4.796997022347357,-0.5079660590613365,1.578216255499028,-0.6999979046598092,-0.17990513363585875,1.7968808074173586,-0.4842032649662147,0.4271675731360321,-0.6999979046598092,1.5982387622118392,0.9421810860656006,-1.3760283681740184,-1.0448235588232042,0.3391886435203106,0.7087780760645422,0.31709249325645056,-0.01943091003423015,-0.46049272408808617,-0.34271037257634035,0.31709249325645056,0.16125438838387834,0.25055651741635415,1.2332184926667917,-0.27264384148485665,0.4490621451928765,-0.38967075507457544,-1.1202684582751312,-0.01943091003423015,-0.156840189674286 | 3,329 |
Regulation of calcium ion transmembrane transport | 6 | 20 | 2.381175 | 0.017258 | P62942,P21796,P78417,P42858,Q00535,Q06787 | Processes and pathways | GO Biological process | msigdb_gobp | 0,64,198,296,495,416 | 2949,1784,563,1586,2863,1475,64,1928,1526,922,296,1602,1239,0,198,495,416,1149,2994,1180 | -0.7485572109498702,-0.203017633379766,0.5362471404769038,-0.13382247009957884,-0.6758024598264976,-0.08792739806811385,2.824517962466285,-0.24938664580266173,-0.1108516474371695,0.2059902824751761,1.0260036903302046,-0.13382247009957884,0.026006314080828572,9.201100736968145,1.4169669380234817,0.6228142321842982,0.7515381995844014,0.07126469850274689,-0.7729219653555064,0.07126469850274689 | 3,329 |
Action tremor | 16 | 59 | 2.374785 | 0.017559 | Q6PJG6,Q99720,Q5T8D3,Q9H6K4,Q9NR77,Q9NQ11,P07602,P31749,O75306,Q5JRX3,P41440,P00846,Q8N2K0,O95140,Q14108,P35637 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 356,194,367,206,15,275,143,209,234,124,55,24,94,248,156,127 | 2980,842,2551,741,810,2652,234,1422,2951,248,3131,24,2821,478,1723,143,2456,1233,2954,2055,1476,1788,1726,209,2508,127,55,2609,2423,750,1854,1367,416,156,1242,1880,124,367,1246,3300,356,3045,94,1247,3298,2847,1394,194,206,275,1017,15,1062,3051,866,1176,1459,1513,3116 | -0.7729219653555064,0.25055651741635415,-0.5079660590613365,0.3391886435203106,0.27277669272882116,-0.5556499880877578,1.2332184926667917,-0.06504940216522562,-0.7485572109498702,1.1920373832406677,-0.9451070759599981,4.04563696990221,-0.6516625684987778,0.6443611882223067,-0.17990513363585875,1.7573792946827045,-0.46049272408808617,0.026006314080828572,-0.7485572109498702,-0.29594995909674393,-0.08792739806811385,-0.203017633379766,-0.17990513363585875,1.3356135768468178,-0.4842032649662147,1.8755510915900018,3.0073424154788886,-0.5317815003956151,-0.4368340474097858,0.3391886435203106,-0.2261780242890793,-0.04221734363056225,0.7515381995844014,1.678038142292685,0.026006314080828572,-0.2261780242890793,1.8951501094270817,0.8578052533050858,0.026006314080828572,-1.8819973434050405,0.8789517589290488,-0.82182395495969,2.262511421655104,0.026006314080828572,-1.8546517595200398,-0.6516625684987778,-0.04221734363056225,1.4372284667550546,1.3763520238062164,1.0885149161930745,0.16125438838387834,4.533482019529468,0.1388221277863417,-0.82182395495969,0.25055651741635415,0.07126469850274689,-0.06504940216522562,-0.08792739806811385,-0.8956151662633678 | 3,329 |
Rhizomelia | 8 | 12 | 2.374555 | 0.01757 | Q15125,Q03164,Q9UBM7,Q15392,O15228,O75718,Q14739,Q7RTS9 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 99,551,240,12,489,335,26,28 | 575,489,2860,335,1195,2179,551,26,99,12,28,240 | 0.5145094059098909,0.6228142321842982,-0.6758024598264976,0.9211394780417321,0.04865771165184635,-0.34271037257634035,0.5579462590868453,3.908602733869772,2.2051248024821013,4.796997022347357,3.874170839925339,1.2332184926667917 | 3,329 |
Protein maturation | 13 | 74 | 2.37325 | 0.017632 | P62942,O75844,Q5VZE5,Q9BU23,Q9BXS4,Q15392,Q5JRX3,Q8N4Q1,P42892,O75503,Q86UY6,Q9UMY4,O75976 | Processes and pathways | GO Biological process | msigdb_gobp | 0,131,324,221,139,12,124,50,82,54,58,158,254 | 3055,1713,2597,1987,54,1422,131,254,2819,744,2655,3097,3132,2350,2601,3099,2863,658,3036,2461,1795,620,527,1729,82,821,2562,2712,1936,0,339,479,709,888,1370,889,1677,12,124,2623,324,3175,2479,58,50,3163,1332,3127,802,939,671,1760,2763,467,570,717,221,389,446,806,139,2766,2102,3179,1829,1017,675,2888,1832,1636,2333,158,1459,1513 | -0.8463621203281708,-0.17990513363585875,-0.5317815003956151,-0.27264384148485665,3.0073424154788886,-0.06504940216522562,1.8165897720528055,1.1713983468947904,-0.6516625684987778,0.3391886435203106,-0.5556499880877578,-0.8956151662633678,-0.9451070759599981,-0.41322685082973565,-0.5317815003956151,-0.8956151662633678,-0.6758024598264976,0.4271675731360321,-0.82182395495969,-0.46049272408808617,-0.203017633379766,0.4709171468581955,0.5796069942263014,-0.17990513363585875,2.452198066890038,0.27277669272882116,-0.5079660590613365,-0.5795719264467128,-0.24938664580266173,9.201100736968145,0.9211394780417321,0.6443611882223067,0.3832587355956147,0.22829447058781055,-0.04221734363056225,0.22829447058781055,-0.156840189674286,4.796997022347357,1.8951501094270817,-0.5317815003956151,0.9421810860656006,-1.0198015679513603,-0.46049272408808617,2.9891561548194527,3.1340610333831447,-0.9948418387058783,-0.01943091003423015,-0.9203310164531874,0.2949552633600194,0.2059902824751761,0.4271675731360321,-0.17990513363585875,-0.6035477250676271,0.6658706672953714,0.5362471404769038,0.3832587355956147,1.2947503089070345,0.815405949185715,0.7087780760645422,0.2949552633600194,1.7968808074173586,-0.6035477250676271,-0.29594995909674393,-1.0198015679513603,-0.203017633379766,0.16125438838387834,0.4271675731360321,-0.6758024598264976,-0.203017633379766,-0.13382247009957884,-0.38967075507457544,1.678038142292685,-0.06504940216522562,-0.08792739806811385 | 3,329 |
Cation transmembrane transporter activity | 17 | 65 | 2.372457 | 0.01767 | Q7KZN9,Q93050,P20674,Q9Y619,Q96QD8,P12235,O75964,Q9HD20,O43772,Q9HC07,Q9UDW1,Q9NQ11,Q9Y487,Q00535,P00846,P16615,Q70HW3 | Functions | GO Molecular function | msigdb_gomf | 483,164,351,39,370,266,104,140,44,222,175,275,149,495,24,490,27 | 915,44,1024,919,104,2951,790,3302,24,845,1784,846,2228,2350,2706,1584,1074,1651,266,1471,490,1076,351,816,3149,748,3085,769,1077,1029,2239,642,2956,661,727,884,1276,1541,1002,495,796,1375,27,483,715,1047,2583,3164,164,539,587,370,1971,946,1901,1828,222,140,275,175,1909,1637,149,1834,39 | 0.2059902824751761,3.33117123497569,0.1388221277863417,0.2059902824751761,2.1089741942010813,-0.7485572109498702,0.2949552633600194,-1.9922392137678377,4.04563696990221,0.25055651741635415,-0.203017633379766,0.25055651741635415,-0.3661653856138045,-0.41322685082973565,-0.5795719264467128,-0.13382247009957884,0.11634661657064145,-0.156840189674286,1.1092852207351331,-0.08792739806811385,0.6228142321842982,0.11634661657064145,0.8789517589290488,0.27277669272882116,-0.9699438469321776,0.3391886435203106,-0.8709590302873479,0.31709249325645056,0.11634661657064145,0.1388221277863417,-0.3661653856138045,0.4490621451928765,-0.7485572109498702,0.4271675731360321,0.3612439724526373,0.22829447058781055,0.0033102074454991735,-0.1108516474371695,0.16125438838387834,0.6228142321842982,0.2949552633600194,-0.04221734363056225,3.908602733869772,0.6443611882223067,0.3832587355956147,0.1388221277863417,-0.5079660590613365,-0.9948418387058783,1.6182320603396134,0.5796069942263014,0.5145094059098909,0.8578052533050858,-0.24938664580266173,0.2059902824751761,-0.2261780242890793,-0.203017633379766,1.2947503089070345,1.7968808074173586,1.0885149161930745,1.55816439445645,-0.2261780242890793,-0.13382247009957884,1.7177654379588205,-0.203017633379766,3.52590265888114 | 3,329 |
Horizontal nystagmus | 7 | 26 | 2.368314 | 0.017869 | Q9H061,Q9NSE4,O95831,P07602,P00846,O60313,P04062 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 260,265,105,143,24,217,191 | 2924,740,842,741,217,873,105,24,191,143,1476,817,822,2957,1854,1275,1246,2963,260,2850,275,265,1062,3051,866,1459 | -0.724249340547183,0.3391886435203106,0.25055651741635415,0.3391886435203106,1.2947503089070345,0.22829447058781055,2.1089741942010813,4.04563696990221,1.4372284667550546,1.7573792946827045,-0.08792739806811385,0.27277669272882116,0.27277669272882116,-0.7485572109498702,-0.2261780242890793,0.0033102074454991735,0.026006314080828572,-0.7485572109498702,1.1713983468947904,-0.6516625684987778,1.0885149161930745,1.1300224418606861,0.1388221277863417,-0.82182395495969,0.25055651741635415,-0.06504940216522562 | 3,329 |
Metalloendopeptidase activity | 8 | 15 | 2.360117 | 0.018269 | P78536,O75844,P42892,Q96TA2,Q92905,Q99797,Q9BYT8,Q5JRX3 | Functions | GO Molecular function | msigdb_gomf | 479,131,82,467,602,570,345,124 | 2286,1987,131,1473,1593,82,621,479,888,124,602,467,570,345,1513 | -0.38967075507457544,-0.27264384148485665,1.8165897720528055,-0.08792739806811385,-0.13382247009957884,2.452198066890038,0.4709171468581955,0.6443611882223067,0.22829447058781055,1.8951501094270817,0.4927328204863091,0.6658706672953714,0.5362471404769038,0.900063101102262,-0.08792739806811385 | 3,329 |
Cytosolic calcium ion transport | 6 | 23 | 2.359344 | 0.018307 | P62942,P21796,P78417,P42858,Q8WWC4,P16615 | Processes and pathways | GO Biological process | msigdb_gobp | 0,64,198,296,407,490 | 2949,790,563,490,2863,1475,1076,64,1928,1526,922,296,1239,0,198,1149,1951,937,1047,407,1760,2727,1513 | -0.7485572109498702,0.2949552633600194,0.5362471404769038,0.6228142321842982,-0.6758024598264976,-0.08792739806811385,0.11634661657064145,2.824517962466285,-0.24938664580266173,-0.1108516474371695,0.2059902824751761,1.0260036903302046,0.026006314080828572,9.201100736968145,1.4169669380234817,0.07126469850274689,-0.24938664580266173,0.2059902824751761,0.1388221277863417,0.7728635640285376,-0.17990513363585875,-0.5795719264467128,-0.08792739806811385 | 3,329 |
Downstream signaling events of b cell receptor bcr | 7 | 45 | 2.354621 | 0.018542 | P62942,P28070,P25786,P20618,P28074,P49721,P28072 | Processes and pathways | Reactome Pathways | msigdb_reactome | 0,129,257,167,147,59,60 | 761,3194,1573,2698,1918,561,1139,508,2505,3084,167,257,1193,991,1656,2661,129,60,147,2417,2790,2608,996,59,1535,1735,297,1438,1603,2003,1542,0,2132,2071,2871,2524,2373,2075,1122,1888,604,2322,1910,2108,3117 | 0.31709249325645056,-1.0699083431145306,-0.13382247009957884,-0.5795719264467128,-0.24938664580266173,0.5362471404769038,0.07126469850274689,0.6012295760038491,-0.4842032649662147,-0.8709590302873479,1.5982387622118392,1.1713983468947904,0.04865771165184635,0.16125438838387834,-0.156840189674286,-0.5556499880877578,1.8362710532052997,2.897905946491273,1.7375864773292968,-0.4368340474097858,-0.6275777989300914,-0.5317815003956151,0.16125438838387834,2.970948746307514,-0.1108516474371695,-0.17990513363585875,1.0260036903302046,-0.06504940216522562,-0.13382247009957884,-0.27264384148485665,-0.1108516474371695,9.201100736968145,-0.3193053506689896,-0.29594995909674393,-0.6758024598264976,-0.4842032649662147,-0.41322685082973565,-0.29594995909674393,0.09382756959687372,-0.2261780242890793,0.4927328204863091,-0.38967075507457544,-0.2261780242890793,-0.29594995909674393,-0.8956151662633678 | 3,329 |
Abnormal conjunctiva morphology | 10 | 24 | 2.329954 | 0.019809 | P10619,P28070,Q9NSE4,P31749,P34897,P06280,Q9NZ08,P49327,Q14739,Q13510 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 88,129,265,209,272,460,87,342,26,437 | 2114,614,477,791,2705,460,88,2782,1233,2954,1525,1726,129,2955,209,272,342,2828,1037,437,26,804,265,87 | -0.3193053506689896,0.4709171468581955,0.6443611882223067,0.2949552633600194,-0.5795719264467128,0.6658706672953714,2.3196739353976064,-0.6275777989300914,0.026006314080828572,-0.7485572109498702,-0.1108516474371695,-0.17990513363585875,1.8362710532052997,-0.7485572109498702,1.3356135768468178,1.0885149161930745,0.900063101102262,-0.6516625684987778,0.1388221277863417,0.7087780760645422,3.908602733869772,0.2949552633600194,1.1300224418606861,2.3766152947125034 | 3,329 |
Lysosomal lumen | 25 | 37 | 2.325948 | 0.020021 | P50897,P46976,Q8NHP8,Q8IV08,Q9NQ11,P07602,Q14108,P08236,P04066,P17900,P61916,Q9UMR5,Q13510,P04062,O43681,Q9NZJ7,P07858,P10619,P10253,P06280,O14773,P38435,Q9UM22,P11117,P54802 | Localization | GO Cellular component | msigdb_gocc | 128,512,394,269,275,143,156,656,791,411,795,176,437,191,810,866,336,88,847,460,842,229,108,745,622 | 1775,1067,842,810,191,791,460,1190,143,2822,336,1263,656,847,88,745,1428,2953,848,2557,411,229,3314,512,128,622,795,437,156,269,1886,394,1395,275,866,108,176 | -0.203017633379766,0.11634661657064145,0.25055651741635415,0.27277669272882116,1.4372284667550546,0.2949552633600194,0.6658706672953714,0.04865771165184635,1.7573792946827045,-0.6516625684987778,0.9211394780417321,0.0033102074454991735,0.4271675731360321,0.25055651741635415,2.3196739353976064,0.3391886435203106,-0.06504940216522562,-0.7485572109498702,0.25055651741635415,-0.5079660590613365,0.7515381995844014,1.253760908657221,-2.566124906447607,0.6012295760038491,1.8755510915900018,0.4709171468581955,0.2949552633600194,0.7087780760645422,1.678038142292685,1.1092852207351331,-0.2261780242890793,0.7941527445250331,-0.04221734363056225,1.0885149161930745,0.25055651741635415,2.089667102484907,1.55816439445645 | 3,329 |
Inorganic molecular entity transmembrane transporter activity | 35 | 72 | 2.323115 | 0.020173 | Q9UBX3,P47985,P12235,Q9HD20,Q96ER9,Q9NQ11,P31930,Q9Y487,P00846,Q96S66,Q13423,P51790,Q93050,O95202,Q9UDW1,Q99797,P21281,O43681,P21796,P45880,Q8N4V1,Q9Y277,Q9HC07,P05023,P55011,Q7KZN9,P20674,Q96QD8,Q02978,O75964,Q9H813,P24539,P0CG08,Q00535,P16615 | Functions | GO Molecular function | msigdb_gomf | 398,642,266,140,539,275,769,149,24,284,796,661,164,790,175,570,816,810,64,67,715,870,222,845,727,483,351,370,106,104,504,748,616,495,490 | 2925,915,2817,810,919,104,2951,790,3302,24,845,1784,846,2228,2350,2706,1584,1074,616,1651,266,1471,490,1076,351,816,3149,64,748,3085,769,1077,1029,2239,67,642,2956,661,727,884,1276,1541,1002,495,106,796,1327,483,715,1047,3164,164,539,370,284,570,1055,1971,946,504,1901,222,140,275,398,175,1909,1637,870,149,1834,2164 | -0.724249340547183,0.2059902824751761,-0.6516625684987778,0.27277669272882116,0.2059902824751761,2.1089741942010813,-0.7485572109498702,0.2949552633600194,-1.9922392137678377,4.04563696990221,0.25055651741635415,-0.203017633379766,0.25055651741635415,-0.3661653856138045,-0.41322685082973565,-0.5795719264467128,-0.13382247009957884,0.11634661657064145,0.4709171468581955,-0.156840189674286,1.1092852207351331,-0.08792739806811385,0.6228142321842982,0.11634661657064145,0.8789517589290488,0.27277669272882116,-0.9699438469321776,2.824517962466285,0.3391886435203106,-0.8709590302873479,0.31709249325645056,0.11634661657064145,0.1388221277863417,-0.3661653856138045,2.750779178310562,0.4490621451928765,-0.7485572109498702,0.4271675731360321,0.3612439724526373,0.22829447058781055,0.0033102074454991735,-0.1108516474371695,0.16125438838387834,0.6228142321842982,2.089667102484907,0.2949552633600194,-0.01943091003423015,0.6443611882223067,0.3832587355956147,0.1388221277863417,-0.9948418387058783,1.6182320603396134,0.5796069942263014,0.8578052533050858,1.0677113479047518,0.5362471404769038,0.1388221277863417,-0.24938664580266173,0.2059902824751761,0.6228142321842982,-0.2261780242890793,1.2947503089070345,1.7968808074173586,1.0885149161930745,0.7941527445250331,1.55816439445645,-0.2261780242890793,-0.13382247009957884,0.25055651741635415,1.7177654379588205,-0.203017633379766,-0.3193053506689896 | 3,329 |
Transmembrane transport | 45 | 211 | 2.310248 | 0.020874 | P62942,O75844,Q9UBX3,Q99523,P12235,Q9HD20,Q8WTV0,Q9NS69,Q9NQ11,Q8WWC4,P00846,Q70HW3,Q06787,Q99595,Q9Y619,P42858,O43772,Q9UDW1,Q6NT16,Q8N4Q1,P41440,P04062,P21796,Q9BSK2,P45880,Q8IXU6,Q9H2D1,P78417,Q15041,Q15629,P23786,P31749,Q9HC07,O95563,P20674,O95831,O75964,Q02978,P38435,Q96QD8,Q03518,Q9UHG3,O14925,Q6P4A7,Q01469 | Processes and pathways | GO Biological process | msigdb_gobp | 0,131,398,138,266,140,14,16,275,407,24,27,416,35,39,296,44,175,49,50,55,191,64,66,67,68,69,198,199,74,77,209,222,93,351,105,104,106,229,370,110,113,241,376,375 | 1772,1352,2925,2039,915,2947,241,2817,701,956,44,1024,1466,2949,917,2652,2653,3240,1187,2343,1987,1718,131,2454,919,104,2168,2951,790,93,2779,105,1782,3302,24,2821,191,845,1784,846,1785,2228,2350,1583,2706,433,1584,1074,616,563,1651,3099,1586,266,1265,1471,490,2863,1475,1076,351,816,3149,2743,64,77,748,3085,1027,1928,1526,1658,1479,922,209,769,1792,1594,1480,1077,1029,229,2239,55,296,67,3171,642,2956,793,1482,1237,822,961,661,464,1664,413,1602,2246,727,884,1276,1665,3017,1541,1239,0,198,1002,495,375,106,110,1241,1858,416,1149,1281,2994,926,796,581,1202,1121,1204,199,2574,1613,74,1375,731,1614,49,585,2137,376,1445,27,483,3244,1951,68,937,50,715,1683,2582,1047,2583,1816,856,1955,14,407,3164,539,1760,587,370,1499,2847,138,35,1694,1893,570,673,2727,756,66,2970,758,1896,1055,1971,1254,69,946,3192,2692,1901,1828,1396,222,140,1132,1399,275,631,16,1906,1307,398,175,783,1134,113,1909,652,1636,1407,1637,1180,870,2163,3008,637,1513,39,2164 | -0.203017633379766,-0.04221734363056225,-0.724249340547183,-0.29594995909674393,0.2059902824751761,-0.7485572109498702,1.2126440410867516,-0.6516625684987778,0.3832587355956147,0.18364368033144304,3.33117123497569,0.1388221277863417,-0.08792739806811385,-0.7485572109498702,0.2059902824751761,-0.5556499880877578,-0.5556499880877578,-1.2473063987901896,0.04865771165184635,-0.41322685082973565,-0.27264384148485665,-0.17990513363585875,1.8165897720528055,-0.46049272408808617,0.2059902824751761,2.1089741942010813,-0.34271037257634035,-0.7485572109498702,0.2949552633600194,2.262511421655104,-0.6275777989300914,2.1089741942010813,-0.203017633379766,-1.9922392137678377,4.04563696990221,-0.6516625684987778,1.4372284667550546,0.25055651741635415,-0.203017633379766,0.25055651741635415,-0.203017633379766,-0.3661653856138045,-0.41322685082973565,-0.13382247009957884,-0.5795719264467128,0.7087780760645422,-0.13382247009957884,0.11634661657064145,0.4709171468581955,0.5362471404769038,-0.156840189674286,-0.8956151662633678,-0.13382247009957884,1.1092852207351331,0.0033102074454991735,-0.08792739806811385,0.6228142321842982,-0.6758024598264976,-0.08792739806811385,0.11634661657064145,0.8789517589290488,0.27277669272882116,-0.9699438469321776,-0.6035477250676271,2.824517962466285,2.546140982982583,0.3391886435203106,-0.8709590302873479,0.1388221277863417,-0.24938664580266173,-0.1108516474371695,-0.156840189674286,-0.08792739806811385,0.2059902824751761,1.3356135768468178,0.31709249325645056,-0.203017633379766,-0.13382247009957884,-0.08792739806811385,0.11634661657064145,0.1388221277863417,1.253760908657221,-0.3661653856138045,3.0073424154788886,1.0260036903302046,2.750779178310562,-1.0198015679513603,0.4490621451928765,-0.7485572109498702,0.2949552633600194,-0.08792739806811385,0.026006314080828572,0.27277669272882116,0.18364368033144304,0.4271675731360321,0.6658706672953714,-0.156840189674286,0.7515381995844014,-0.13382247009957884,-0.3661653856138045,0.3612439724526373,0.22829447058781055,0.0033102074454991735,-0.156840189674286,-0.7973440593945568,-0.1108516474371695,0.026006314080828572,9.201100736968145,1.4169669380234817,0.16125438838387834,0.6228142321842982,0.8366233840884401,2.089667102484907,2.0509750105284508,0.026006314080828572,-0.2261780242890793,0.7515381995844014,0.07126469850274689,0.0033102074454991735,-0.7729219653555064,0.2059902824751761,0.2949552633600194,0.5145094059098909,0.04865771165184635,0.09382756959687372,0.04865771165184635,1.4169669380234817,-0.5079660590613365,-0.13382247009957884,2.6022259510613153,-0.04221734363056225,0.3612439724526373,-0.13382247009957884,3.2060189747398833,0.5145094059098909,-0.3193053506689896,0.8366233840884401,-0.06504940216522562,3.908602733869772,0.6443611882223067,-1.2473063987901896,-0.24938664580266173,2.7322889967086703,0.2059902824751761,3.1340610333831447,0.3832587355956147,-0.156840189674286,-0.5079660590613365,0.1388221277863417,-0.5079660590613365,-0.203017633379766,0.25055651741635415,-0.24938664580266173,4.747880134126402,0.7728635640285376,-0.9948418387058783,0.5796069942263014,-0.17990513363585875,0.5145094059098909,0.8578052533050858,-0.08792739806811385,-0.6516625684987778,1.7968808074173586,3.64862783763913,-0.156840189674286,-0.2261780242890793,0.5362471404769038,0.4271675731360321,-0.5795719264467128,0.3391886435203106,2.7692470748533924,-0.7485572109498702,0.3391886435203106,-0.2261780242890793,0.1388221277863417,-0.24938664580266173,0.026006314080828572,2.7322889967086703,0.2059902824751761,-1.0448235588232042,-0.5556499880877578,-0.2261780242890793,-0.203017633379766,-0.04221734363056225,1.2947503089070345,1.7968808074173586,0.09382756959687372,-0.04221734363056225,1.0885149161930745,0.4709171468581955,4.533482019529468,-0.2261780242890793,0.0033102074454991735,0.7941527445250331,1.55816439445645,0.31709249325645056,0.09382756959687372,2.031589771535772,-0.2261780242890793,0.4490621451928765,-0.13382247009957884,-0.04221734363056225,-0.13382247009957884,0.07126469850274689,0.25055651741635415,-0.3193053506689896,-0.7729219653555064,0.4709171468581955,-0.08792739806811385,3.52590265888114,-0.3193053506689896 | 3,329 |
Abnormal circulating cholesterol concentration | 9 | 36 | 2.302686 | 0.021297 | Q15125,P37268,P42858,Q8IWV7,Q9UBM7,Q15392,Q15800,P07602,Q14739 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 99,7,296,168,240,12,173,143,26 | 988,2455,2656,1313,143,3134,7,3314,296,492,528,2668,998,795,2430,709,826,1202,26,99,12,2576,173,1747,668,168,327,3269,753,2484,779,1018,866,240,652,1709 | 0.16125438838387834,-0.46049272408808617,-0.5556499880877578,-0.01943091003423015,1.7573792946827045,-0.9451070759599981,5.721954661682018,-2.566124906447607,1.0260036903302046,0.6228142321842982,0.5796069942263014,-0.5556499880877578,0.16125438838387834,0.2949552633600194,-0.4368340474097858,0.3832587355956147,0.27277669272882116,0.04865771165184635,3.908602733869772,2.2051248024821013,4.796997022347357,-0.5079660590613365,1.578216255499028,-0.17990513363585875,0.4271675731360321,1.5982387622118392,0.9421810860656006,-1.3760283681740184,0.3391886435203106,-0.46049272408808617,0.31709249325645056,0.16125438838387834,0.25055651741635415,1.2332184926667917,0.4490621451928765,-0.156840189674286 | 3,329 |
Polyneuropathy | 7 | 18 | 2.301995 | 0.021335 | Q15041,O95831,P07602,P00846,Q8N2K0,Q15120,O60313 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 199,105,143,24,94,250,217 | 217,312,105,24,2821,791,143,2505,769,3121,1367,199,250,1881,94,3269,866,2403 | 1.2947503089070345,0.9631881196187747,2.1089741942010813,4.04563696990221,-0.6516625684987778,0.2949552633600194,1.7573792946827045,-0.4842032649662147,0.31709249325645056,-0.9203310164531874,-0.04221734363056225,1.4169669380234817,1.1920373832406677,-0.2261780242890793,2.262511421655104,-1.3760283681740184,0.25055651741635415,-0.41322685082973565 | 3,329 |
Abnormal femoral neck head morphology | 13 | 48 | 2.298822 | 0.021515 | O75844,Q9Y619,O95613,O95831,Q7LGA3,Q99575,O75718,Q96AY3,Q9Y487,O43909,P28482,Q14739,Q7RTS9 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 131,39,452,105,426,503,335,21,149,185,374,26,28 | 2697,1067,185,843,2860,988,335,131,452,105,2656,791,509,2557,2743,2232,374,2606,995,2666,2179,822,1437,727,3017,26,2374,2755,3068,1290,2841,426,28,3071,626,21,2204,2144,503,1216,779,1973,950,1410,2032,149,1708,39 | -0.5795719264467128,0.11634661657064145,1.47766044819358,0.25055651741635415,-0.6758024598264976,0.16125438838387834,0.9211394780417321,1.8165897720528055,0.6873428903362069,2.1089741942010813,-0.5556499880877578,0.2949552633600194,0.6012295760038491,-0.5079660590613365,-0.6035477250676271,-0.3661653856138045,0.8366233840884401,-0.5317815003956151,0.16125438838387834,-0.5556499880877578,-0.34271037257634035,0.27277669272882116,-0.06504940216522562,0.3612439724526373,-0.7973440593945568,3.908602733869772,-0.41322685082973565,-0.6035477250676271,-0.8463621203281708,0.0033102074454991735,-0.6516625684987778,0.7301764410183317,3.874170839925339,-0.8463621203281708,0.4709171468581955,4.249159388964148,-0.34271037257634035,-0.3193053506689896,0.6228142321842982,0.04865771165184635,0.31709249325645056,-0.24938664580266173,0.2059902824751761,-0.04221734363056225,-0.27264384148485665,1.7177654379588205,-0.156840189674286,3.52590265888114 | 3,329 |
Inorganic anion transport | 12 | 22 | 2.29693 | 0.021623 | P21796,P08183,P51790,P45880,Q9UBX3,Q02978,Q9H813,P54105,Q9UHG3,P0CG08,P30536,Q96S66 | Processes and pathways | GO Biological process | msigdb_gobp | 64,433,661,67,398,106,504,706,113,616,212,284 | 2925,2817,810,433,616,64,212,67,661,706,727,1002,106,1327,284,1055,2211,504,398,113,870,2164 | -0.724249340547183,-0.6516625684987778,0.27277669272882116,0.7087780760645422,0.4709171468581955,2.824517962466285,1.3151976269095578,2.750779178310562,0.4271675731360321,0.3832587355956147,0.3612439724526373,0.16125438838387834,2.089667102484907,-0.01943091003423015,1.0677113479047518,0.1388221277863417,-0.34271037257634035,0.6228142321842982,0.7941527445250331,2.031589771535772,0.25055651741635415,-0.3193053506689896 | 3,329 |
Cytochrome complex assembly | 6 | 13 | 2.287489 | 0.022167 | Q9BSK2,P53701,Q15070,Q9Y2R0,Q69YU5,Q6DKK2 | Processes and pathways | GO Biological process | msigdb_gobp | 66,132,200,134,48,186 | 2045,311,642,132,200,48,186,483,861,756,66,3145,134 | -0.29594995909674393,0.9631881196187747,0.4490621451928765,1.8165897720528055,1.4169669380234817,3.2239578076854247,1.47766044819358,0.6443611882223067,0.25055651741635415,0.3391886435203106,2.7692470748533924,-0.9451070759599981,1.8165897720528055 | 3,329 |
Transmembrane transporter binding | 9 | 32 | 2.28421 | 0.022359 | P62942,P21796,P42858,Q9Y4C2,P30536,P16615,P0DP25,Q06787,Q9Y639 | Functions | GO Molecular function | msigdb_gomf | 0,64,296,637,212,490,563,416,95 | 956,2949,2655,1469,563,1112,2230,490,2743,64,1928,212,922,2059,1594,296,1936,1239,0,1737,1241,416,926,1202,2257,1951,2635,673,1132,1399,637,95 | 0.18364368033144304,-0.7485572109498702,-0.5556499880877578,-0.08792739806811385,0.5362471404769038,0.09382756959687372,-0.3661653856138045,0.6228142321842982,-0.6035477250676271,2.824517962466285,-0.24938664580266173,1.3151976269095578,0.2059902824751761,-0.29594995909674393,-0.13382247009957884,1.0260036903302046,-0.24938664580266173,0.026006314080828572,9.201100736968145,-0.17990513363585875,0.026006314080828572,0.7515381995844014,0.2059902824751761,0.04865771165184635,-0.3661653856138045,-0.24938664580266173,-0.5317815003956151,0.4271675731360321,0.09382756959687372,-0.04221734363056225,0.4709171468581955,2.262511421655104 | 3,329 |
Signaling by the b cell receptor bcr | 7 | 47 | 2.277492 | 0.022757 | P62942,P28070,P25786,P20618,P28074,P49721,P28072 | Processes and pathways | Reactome Pathways | msigdb_reactome | 0,129,257,167,147,59,60 | 761,3194,1573,2698,1918,561,1139,1466,508,2505,3084,167,257,1193,991,1656,2661,129,60,147,2417,2790,2608,996,59,1535,1735,297,1438,1603,2003,1542,0,382,2132,2071,2871,2524,2373,2075,1122,1888,604,2322,1910,2108,3117 | 0.31709249325645056,-1.0699083431145306,-0.13382247009957884,-0.5795719264467128,-0.24938664580266173,0.5362471404769038,0.07126469850274689,-0.08792739806811385,0.6012295760038491,-0.4842032649662147,-0.8709590302873479,1.5982387622118392,1.1713983468947904,0.04865771165184635,0.16125438838387834,-0.156840189674286,-0.5556499880877578,1.8362710532052997,2.897905946491273,1.7375864773292968,-0.4368340474097858,-0.6275777989300914,-0.5317815003956151,0.16125438838387834,2.970948746307514,-0.1108516474371695,-0.17990513363585875,1.0260036903302046,-0.06504940216522562,-0.13382247009957884,-0.27264384148485665,-0.1108516474371695,9.201100736968145,0.815405949185715,-0.3193053506689896,-0.29594995909674393,-0.6758024598264976,-0.4842032649662147,-0.41322685082973565,-0.29594995909674393,0.09382756959687372,-0.2261780242890793,0.4927328204863091,-0.38967075507457544,-0.2261780242890793,-0.29594995909674393,-0.8956151662633678 | 3,329 |
Abnormal biliary tract morphology | 6 | 22 | 2.276759 | 0.022801 | P14174,P07602,P09601,Q14739,Q14108,P04062 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 256,143,53,26,156,191 | 810,2656,191,143,53,256,2708,1595,822,1600,888,645,156,26,355,2390,943,720,866,809,3145,1351 | 0.27277669272882116,-0.5556499880877578,1.4372284667550546,1.7573792946827045,3.025507611654335,1.1713983468947904,-0.5795719264467128,-0.13382247009957884,0.27277669272882116,-0.13382247009957884,0.22829447058781055,0.4490621451928765,1.678038142292685,3.908602733869772,0.8789517589290488,-0.41322685082973565,0.2059902824751761,0.3832587355956147,0.25055651741635415,0.2949552633600194,-0.9451070759599981,-0.01943091003423015 | 3,329 |
Biological oxidations | 7 | 46 | 2.269631 | 0.02323 | P07099,Q16850,O15217,Q9UJ14,Q9NUJ1,Q96DG6,O43169 | Processes and pathways | Reactome Pathways | msigdb_reactome | 96,193,2,133,45,178,62 | 3055,1416,2,62,742,2650,2341,1919,2820,3058,2048,96,1469,2459,2119,3034,1589,2708,423,2987,2415,1526,992,1317,2062,2609,2298,198,830,193,2934,625,3175,1816,692,178,3074,2636,1302,1761,45,838,632,1308,133,2404 | -0.8463621203281708,-0.06504940216522562,7.076334795635697,2.861255449875855,0.3391886435203106,-0.5556499880877578,-0.41322685082973565,-0.24938664580266173,-0.6516625684987778,-0.8463621203281708,-0.29594995909674393,2.243407596862186,-0.08792739806811385,-0.46049272408808617,-0.3193053506689896,-0.82182395495969,-0.13382247009957884,-0.5795719264467128,0.7301764410183317,-0.7729219653555064,-0.4368340474097858,-0.1108516474371695,0.16125438838387834,-0.01943091003423015,-0.29594995909674393,-0.5317815003956151,-0.38967075507457544,1.4169669380234817,0.27277669272882116,1.4372284667550546,-0.724249340547183,0.4709171468581955,-1.0198015679513603,-0.203017633379766,0.40523318577404505,1.5380830320941858,-0.8463621203281708,-0.5317815003956151,0.0033102074454991735,-0.17990513363585875,3.33117123497569,0.27277669272882116,0.4709171468581955,0.0033102074454991735,1.8165897720528055,-0.41322685082973565 | 3,329 |
Regulation of cellular ph | 6 | 22 | 2.268661 | 0.023289 | P50897,Q8N511,Q93050,Q9Y487,O75503,Q9HC07 | Processes and pathways | GO Biological process | msigdb_gobp | 128,327,164,149,54,222 | 54,1422,2228,616,3086,374,128,1852,661,1280,1747,327,833,164,804,1893,222,1345,1134,1909,149,2164 | 3.0073424154788886,-0.06504940216522562,-0.3661653856138045,0.4709171468581955,-0.8709590302873479,0.8366233840884401,1.8755510915900018,-0.2261780242890793,0.4271675731360321,0.0033102074454991735,-0.17990513363585875,0.9421810860656006,0.27277669272882116,1.6182320603396134,0.2949552633600194,-0.2261780242890793,1.2947503089070345,-0.01943091003423015,0.09382756959687372,-0.2261780242890793,1.7177654379588205,-0.3193053506689896 | 3,329 |
Regulation of ph | 6 | 22 | 2.268661 | 0.023289 | P50897,Q8N511,Q93050,Q9Y487,O75503,Q9HC07 | Processes and pathways | GO Biological process | msigdb_gobp | 128,327,164,149,54,222 | 54,1422,2228,616,3086,374,128,1852,661,1280,1747,327,833,164,804,1893,222,1345,1134,1909,149,2164 | 3.0073424154788886,-0.06504940216522562,-0.3661653856138045,0.4709171468581955,-0.8709590302873479,0.8366233840884401,1.8755510915900018,-0.2261780242890793,0.4271675731360321,0.0033102074454991735,-0.17990513363585875,0.9421810860656006,0.27277669272882116,1.6182320603396134,0.2949552633600194,-0.2261780242890793,1.2947503089070345,-0.01943091003423015,0.09382756959687372,-0.2261780242890793,1.7177654379588205,-0.3193053506689896 | 3,329 |
Skin nodule | 9 | 24 | 2.252274 | 0.024305 | Q9NSE4,O75874,P31749,P48735,Q9NZ08,P49327,P06280,Q13510,P35637 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 265,76,209,22,87,342,460,437,127 | 1418,76,2455,614,460,746,490,1525,703,209,3134,2059,127,22,342,1598,883,2430,1858,437,901,265,87,3095 | -0.06504940216522562,2.546140982982583,-0.46049272408808617,0.4709171468581955,0.6658706672953714,0.3391886435203106,0.6228142321842982,-0.1108516474371695,0.3832587355956147,1.3356135768468178,-0.9451070759599981,-0.29594995909674393,1.8755510915900018,4.1646493114890495,0.900063101102262,-0.13382247009957884,0.22829447058781055,-0.4368340474097858,-0.2261780242890793,0.7087780760645422,0.22829447058781055,1.1300224418606861,2.3766152947125034,-0.8709590302873479 | 3,329 |
Steroid biosynthesis | 6 | 11 | 2.250811 | 0.024398 | Q16850,Q15125,P37268,P48449,Q15392,Q15800 | Processes and pathways | KEGG Pathways | msigdb_kegg | 193,99,7,72,12,173 | 960,7,3314,72,530,99,12,2576,173,193,240 | 0.18364368033144304,5.721954661682018,-2.566124906447607,2.6581035741477934,0.5796069942263014,2.2051248024821013,4.796997022347357,-0.5079660590613365,1.578216255499028,1.4372284667550546,1.2332184926667917 | 3,329 |
Increased susceptibility to fractures | 9 | 53 | 2.244248 | 0.024816 | Q32P28,P22626,O75874,Q13126,Q96AY3,P48735,Q14739,Q14108,P04062 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 37,202,76,84,21,22,26,156,191 | 2926,2947,765,216,812,843,2114,335,76,2226,1647,1582,1230,191,2411,1841,593,1232,462,3098,1589,2863,202,3309,2290,2604,2059,2176,22,2992,2361,2369,2430,84,2572,712,156,26,37,1617,1624,2686,21,2144,2147,572,1216,2692,2943,3129,1410,3095,1570 | -0.724249340547183,-0.7485572109498702,0.31709249325645056,1.2947503089070345,0.27277669272882116,0.25055651741635415,-0.3193053506689896,0.9211394780417321,2.546140982982583,-0.3661653856138045,-0.156840189674286,-0.13382247009957884,0.026006314080828572,1.4372284667550546,-0.4368340474097858,-0.2261780242890793,0.4927328204863091,0.026006314080828572,0.6658706672953714,-0.8956151662633678,-0.13382247009957884,-0.6758024598264976,1.396674842878999,-2.360677997838574,-0.38967075507457544,-0.5317815003956151,-0.29594995909674393,-0.34271037257634035,4.1646493114890495,-0.7729219653555064,-0.41322685082973565,-0.41322685082973565,-0.4368340474097858,2.4144547648383874,-0.5079660590613365,0.3832587355956147,1.678038142292685,3.908602733869772,3.596143058067744,-0.13382247009957884,-0.13382247009957884,-0.5556499880877578,4.249159388964148,-0.3193053506689896,-0.3193053506689896,0.5362471404769038,0.04865771165184635,-0.5556499880877578,-0.724249340547183,-0.9203310164531874,-0.04221734363056225,-0.8709590302873479,-0.1108516474371695 | 3,329 |
Negative regulation of mrna catabolic process | 9 | 26 | 2.242945 | 0.0249 | Q92804,P98175,Q14011,P35637,P16989,Q14103,Q99729,P67809,O60506 | Processes and pathways | GO Biological process | msigdb_gobp | 103,298,203,127,271,405,317,314,278 | 2223,278,2598,875,639,271,127,314,298,1544,416,1606,730,1864,203,405,929,731,1751,3209,1757,103,317,1015,1634,1411 | -0.3661653856138045,1.0677113479047518,-0.5317815003956151,0.22829447058781055,0.4490621451928765,1.0885149161930745,1.8755510915900018,0.9631881196187747,1.0260036903302046,-0.1108516474371695,0.7515381995844014,-0.13382247009957884,0.3612439724526373,-0.2261780242890793,1.396674842878999,0.7728635640285376,0.2059902824751761,0.3612439724526373,-0.17990513363585875,-1.0950564604153394,-0.17990513363585875,2.1282554740320596,0.9631881196187747,0.16125438838387834,-0.13382247009957884,-0.04221734363056225 | 3,329 |
Chaperone mediated protein folding | 7 | 42 | 2.238855 | 0.025165 | P62942,P26885,Q32P28,Q02790,O75718,Q13451,Q9H2J4 | Processes and pathways | GO Biological process | msigdb_gobp | 0,34,37,83,335,182,214 | 2648,3285,359,2552,335,3059,2351,617,1428,2173,640,1724,2290,2416,34,2606,2745,879,492,819,2512,2001,2359,1602,2002,0,664,83,2372,2072,1740,182,830,37,2723,1760,1693,1500,214,1216,1131,1134 | -0.5556499880877578,-1.6388448115004188,0.8578052533050858,-0.5079660590613365,0.9211394780417321,-0.8463621203281708,-0.41322685082973565,0.4709171468581955,-0.06504940216522562,-0.34271037257634035,0.4490621451928765,-0.17990513363585875,-0.38967075507457544,-0.4368340474097858,3.6835255876420354,-0.5317815003956151,-0.6035477250676271,0.22829447058781055,0.6228142321842982,0.27277669272882116,-0.4842032649662147,-0.27264384148485665,-0.41322685082973565,-0.13382247009957884,-0.27264384148485665,9.201100736968145,0.4271675731360321,2.4144547648383874,-0.41322685082973565,-0.29594995909674393,-0.17990513363585875,1.4978312091341666,0.27277669272882116,3.596143058067744,-0.5795719264467128,-0.17990513363585875,-0.156840189674286,-0.08792739806811385,1.3151976269095578,0.04865771165184635,0.09382756959687372,0.09382756959687372 | 3,329 |
Abnormal cranial nerve physiology | 21 | 73 | 2.235579 | 0.025379 | P11047,P12235,Q9NR77,P07602,P34897,O15360,P48735,P07196,Q92734,Q9UHX1,Q13510,Q7LG56,P51530,Q9Y5P6,Q06210,O75874,P31749,Q96TA2,Q9NZ08,P49327,P42356 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 261,266,15,143,272,401,22,306,444,318,437,189,188,332,323,76,209,467,87,342,219 | 2735,3055,401,2045,2452,459,2343,76,723,614,2656,593,306,143,2982,261,266,921,1525,2986,2058,209,272,1531,879,219,660,22,342,822,961,188,2514,2792,1437,1664,2361,1858,323,2715,2572,2255,437,1285,1742,2754,3090,189,2198,444,2390,754,2810,3024,467,2265,1560,1013,2765,1217,3179,2850,2974,15,3003,87,866,2154,318,1916,1917,2281,332 | -0.6035477250676271,-0.8463621203281708,0.7728635640285376,-0.29594995909674393,-0.46049272408808617,0.6658706672953714,-0.41322685082973565,2.546140982982583,0.3612439724526373,0.4709171468581955,-0.5556499880877578,0.4927328204863091,0.9841607712980948,1.7573792946827045,-0.7729219653555064,1.1507267582378766,1.1092852207351331,0.2059902824751761,-0.1108516474371695,-0.7729219653555064,-0.29594995909674393,1.3356135768468178,1.0885149161930745,-0.1108516474371695,0.22829447058781055,1.2947503089070345,0.4271675731360321,4.1646493114890495,0.900063101102262,0.27277669272882116,0.18364368033144304,1.457459585216246,-0.4842032649662147,-0.6275777989300914,-0.06504940216522562,-0.156840189674286,-0.41322685082973565,-0.2261780242890793,0.9421810860656006,-0.5795719264467128,-0.5079660590613365,-0.3661653856138045,0.7087780760645422,0.0033102074454991735,-0.17990513363585875,-0.6035477250676271,-0.8709590302873479,1.457459585216246,-0.34271037257634035,0.7087780760645422,-0.41322685082973565,0.3391886435203106,-0.6275777989300914,-0.7973440593945568,0.6658706672953714,-0.3661653856138045,-0.1108516474371695,0.16125438838387834,-0.6035477250676271,0.04865771165184635,-1.0198015679513603,-0.6516625684987778,-0.7485572109498702,4.533482019529468,-0.7729219653555064,2.3766152947125034,0.25055651741635415,-0.3193053506689896,0.9631881196187747,-0.2261780242890793,-0.2261780242890793,-0.3661653856138045,0.9421810860656006 | 3,329 |
Micromelia | 6 | 23 | 2.231931 | 0.02562 | Q9UBM7,Q15392,O75874,P48735,Q9UHX1,Q14739 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 240,12,76,22,318,26 | 2223,1777,1714,2895,2860,335,76,452,3098,703,22,2562,886,2256,26,12,1550,3163,2204,240,318,2336,2491 | -0.3661653856138045,-0.203017633379766,-0.17990513363585875,-0.6999979046598092,-0.6758024598264976,0.9211394780417321,2.546140982982583,0.6873428903362069,-0.8956151662633678,0.3832587355956147,4.1646493114890495,-0.5079660590613365,0.22829447058781055,-0.3661653856138045,3.908602733869772,4.796997022347357,-0.1108516474371695,-0.9948418387058783,-0.34271037257634035,1.2332184926667917,0.9631881196187747,-0.38967075507457544,-0.46049272408808617 | 3,329 |
Endoplasmic reticulum lumen | 15 | 63 | 2.223117 | 0.026208 | Q07065,Q32P28,P11047,Q9Y680,Q02818,P13674,P28482,Q9BTY2,O75718,Q96AY3,Q14257,Q9NWM8,O95881,Q9NZ08,O15460 | Localization | GO Cellular component | msigdb_gocc | 161,37,261,170,73,201,374,239,335,21,150,183,305,87,247 | 1775,3285,247,810,391,843,335,744,305,1232,2555,2459,617,261,2173,201,2230,1360,2900,768,2290,3086,2461,1361,374,1527,3037,1363,2562,794,2182,479,73,161,2717,150,1085,1873,2800,1678,37,2434,1008,1551,1330,801,2140,1886,2263,21,1760,1894,2484,239,1131,183,1345,2852,87,2888,3129,3054,170 | -0.203017633379766,-1.6388448115004188,1.1920373832406677,0.27277669272882116,0.7941527445250331,0.25055651741635415,0.9211394780417321,0.3391886435203106,0.9841607712980948,0.026006314080828572,-0.5079660590613365,-0.46049272408808617,0.4709171468581955,1.1507267582378766,-0.34271037257634035,1.396674842878999,-0.3661653856138045,-0.04221734363056225,-0.6999979046598092,0.31709249325645056,-0.38967075507457544,-0.8709590302873479,-0.46049272408808617,-0.04221734363056225,0.8366233840884401,-0.1108516474371695,-0.82182395495969,-0.04221734363056225,-0.5079660590613365,0.2949552633600194,-0.34271037257634035,0.6443611882223067,2.6581035741477934,1.6581316076819692,-0.5795719264467128,1.6979160391392325,0.11634661657064145,-0.2261780242890793,-0.6275777989300914,-0.156840189674286,3.596143058067744,-0.4368340474097858,0.16125438838387834,-0.1108516474371695,-0.01943091003423015,0.2949552633600194,-0.3193053506689896,-0.2261780242890793,-0.3661653856138045,4.249159388964148,-0.17990513363585875,-0.2261780242890793,-0.46049272408808617,1.2332184926667917,0.09382756959687372,1.4978312091341666,-0.01943091003423015,-0.6516625684987778,2.3766152947125034,-0.6758024598264976,-0.9203310164531874,-0.82182395495969,1.5982387622118392 | 3,329 |
Alternative mrna splicing via spliceosome | 20 | 44 | 2.214886 | 0.026768 | Q13242,O60828,Q06787,Q15007,Q9BWF3,P98175,Q92841,Q8NDT2,Q8IY67,O60341,Q9UHX1,Q13247,P51114,O75525,Q07955,P62995,P09651,P51116,O95391,P38159 | Processes and pathways | GO Biological process | msigdb_gobp | 513,525,416,280,557,298,694,691,568,679,318,686,313,196,580,321,462,231,228,236 | 1183,679,525,196,228,462,1075,877,878,2123,994,236,2561,313,231,1731,1320,850,321,298,1544,2369,416,708,580,1606,2305,513,686,280,772,2802,568,691,694,2388,1691,1391,3108,557,318,1411,1569,1708 | 0.04865771165184635,0.40523318577404505,0.5796069942263014,1.4169669380234817,1.253760908657221,0.6658706672953714,0.11634661657064145,0.22829447058781055,0.22829447058781055,-0.3193053506689896,0.16125438838387834,1.2332184926667917,-0.5079660590613365,0.9631881196187747,1.253760908657221,-0.17990513363585875,-0.01943091003423015,0.25055651741635415,0.9421810860656006,1.0260036903302046,-0.1108516474371695,-0.41322685082973565,0.7515381995844014,0.3832587355956147,0.5145094059098909,-0.13382247009957884,-0.38967075507457544,0.6012295760038491,0.40523318577404505,1.0677113479047518,0.31709249325645056,-0.6275777989300914,0.5362471404769038,0.40523318577404505,0.40523318577404505,-0.41322685082973565,-0.156840189674286,-0.04221734363056225,-0.8956151662633678,0.5579462590868453,0.9631881196187747,-0.04221734363056225,-0.1108516474371695,-0.156840189674286 | 3,329 |
Molecular transducer activity | 14 | 37 | 2.211561 | 0.026997 | Q99720,Q5KU26,P15260,Q99523,Q15629,Q9BUN8,Q8WTV0,P20645,O15118,O15173,P30536,Q9UBG0,P49327,Q14108 | Functions | GO Molecular function | msigdb_gomf | 194,514,509,138,74,468,14,365,400,114,212,408,342,156 | 400,114,1422,2951,2499,1785,3264,550,657,509,365,212,2176,342,1036,1859,1368,1441,2008,156,74,1375,1748,514,3070,14,3164,1499,138,194,468,631,2767,2027,408,783,2035 | 0.7728635640285376,1.9732758301648015,-0.06504940216522562,-0.7485572109498702,-0.4842032649662147,-0.203017633379766,-1.3760283681740184,0.5579462590868453,0.4271675731360321,0.6012295760038491,0.8578052533050858,1.3151976269095578,-0.34271037257634035,0.900063101102262,0.1388221277863417,-0.2261780242890793,-0.04221734363056225,-0.06504940216522562,-0.27264384148485665,1.678038142292685,2.6022259510613153,-0.04221734363056225,-0.17990513363585875,0.6012295760038491,-0.8463621203281708,4.747880134126402,-0.9948418387058783,-0.08792739806811385,1.7968808074173586,1.4372284667550546,0.6658706672953714,0.4709171468581955,-0.6035477250676271,-0.27264384148485665,0.7728635640285376,0.31709249325645056,-0.27264384148485665 | 3,329 |
Abnormal peripheral nervous system physiology | 15 | 59 | 2.208114 | 0.027236 | Q5TAQ9,Q99720,Q15125,Q9Y619,O95831,Q9NR77,P07602,O60313,P07196,O15270,Q15120,O95721,O95140,Q7LG56,Q8N2K0 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 259,194,99,39,105,15,143,217,306,216,250,312,248,189,94 | 765,216,810,812,1779,217,1418,248,312,105,2656,3059,306,143,921,2954,1476,769,2746,1115,492,2748,961,1852,1600,2361,2902,3121,1802,1285,712,2074,250,99,259,1617,189,972,94,974,1955,444,3298,3258,194,2210,2692,358,15,2330,3051,866,2154,1176,3078,2281,3116,39,2222 | 0.31709249325645056,1.2947503089070345,0.27277669272882116,0.27277669272882116,-0.203017633379766,1.2947503089070345,-0.06504940216522562,1.1920373832406677,0.9631881196187747,2.1089741942010813,-0.5556499880877578,-0.8463621203281708,0.9841607712980948,1.7573792946827045,0.2059902824751761,-0.7485572109498702,-0.08792739806811385,0.31709249325645056,-0.6035477250676271,0.09382756959687372,0.6228142321842982,-0.6035477250676271,0.18364368033144304,-0.2261780242890793,-0.13382247009957884,-0.41322685082973565,-0.6999979046598092,-0.9203310164531874,-0.203017633379766,0.0033102074454991735,0.3832587355956147,-0.29594995909674393,1.1920373832406677,2.2051248024821013,1.1713983468947904,-0.13382247009957884,1.457459585216246,0.18364368033144304,2.262511421655104,0.18364368033144304,-0.24938664580266173,0.7087780760645422,-1.8546517595200398,-1.3243326104741977,1.4372284667550546,-0.34271037257634035,-0.5556499880877578,0.8789517589290488,4.533482019529468,-0.38967075507457544,-0.82182395495969,0.25055651741635415,-0.3193053506689896,0.07126469850274689,-0.8463621203281708,-0.3661653856138045,-0.8956151662633678,3.52590265888114,-0.34271037257634035 | 3,329 |
Lipid biosynthesis | 13 | 49 | 2.202512 | 0.027629 | Q16739,Q16850,Q15125,Q96G23,P37268,P48449,Q9UBM7,Q15392,Q15800,Q9NZ01,Q14739,P35790,O95674 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 258,193,99,165,7,72,240,12,173,215,26,155,255 | 575,3307,3009,3096,255,3058,3320,2412,155,7,1531,72,660,342,1733,1536,1146,3137,1003,3322,1488,3215,26,99,1807,830,12,2576,173,258,193,567,1127,1159,2963,899,941,165,650,1969,285,2024,606,737,2214,215,397,240,1832 | 0.5145094059098909,-2.2742012256857462,-0.7973440593945568,-0.8956151662633678,1.1713983468947904,-0.8463621203281708,-2.900319427711263,-0.4368340474097858,1.678038142292685,5.721954661682018,-0.1108516474371695,2.6581035741477934,0.4271675731360321,0.900063101102262,-0.17990513363585875,-0.1108516474371695,0.07126469850274689,-0.9451070759599981,0.16125438838387834,-3.057217712868554,-0.08792739806811385,-1.1202684582751312,3.908602733869772,2.2051248024821013,-0.203017633379766,0.27277669272882116,4.796997022347357,-0.5079660590613365,1.578216255499028,1.1713983468947904,1.4372284667550546,0.5362471404769038,0.09382756959687372,0.07126469850274689,-0.7485572109498702,0.22829447058781055,0.2059902824751761,1.6182320603396134,0.4490621451928765,-0.24938664580266173,1.0677113479047518,-0.27264384148485665,0.4927328204863091,0.3612439724526373,-0.34271037257634035,1.3151976269095578,0.7941527445250331,1.2332184926667917,-0.203017633379766 | 3,329 |
Knee flexion contracture | 7 | 27 | 2.201356 | 0.027711 | Q9Y5P6,P37268,Q06210,Q86XL3,Q7LGA3,P23786,Q96AY3 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 332,7,323,107,426,77,21 | 2926,1779,1310,459,1109,873,723,593,2743,1525,2986,77,1234,1844,1029,7,660,2711,323,426,107,716,2320,21,2548,332,2491 | -0.724249340547183,-0.203017633379766,-0.01943091003423015,0.6658706672953714,0.09382756959687372,0.22829447058781055,0.3612439724526373,0.4927328204863091,-0.6035477250676271,-0.1108516474371695,-0.7729219653555064,2.546140982982583,0.026006314080828572,-0.2261780242890793,0.1388221277863417,5.721954661682018,0.4271675731360321,-0.5795719264467128,0.9421810860656006,0.7301764410183317,2.089667102484907,0.3832587355956147,-0.38967075507457544,4.249159388964148,-0.4842032649662147,0.9421810860656006,-0.46049272408808617 | 3,329 |
Mitochondrial membrane organization | 14 | 49 | 2.197558 | 0.027981 | Q5XKP0,P45880,Q15070,Q9BUR5,P12235,Q9NX63,Q9NS69,O14737,Q9H3K2,P52789,Q8WWC4,O95140,Q9Y512,O60313 | Processes and pathways | GO Biological process | msigdb_gobp | 355,67,200,556,266,472,16,359,379,464,407,248,488,217 | 2924,359,812,217,988,2168,248,790,2411,846,1263,2600,563,266,1590,1479,1660,2744,2606,2126,67,1482,2611,822,464,1149,1610,200,773,1614,1088,1808,355,1950,1813,1209,407,556,379,16,1565,472,1346,739,3145,1513,488,1414,1103 | -0.724249340547183,0.8578052533050858,0.27277669272882116,1.2947503089070345,0.16125438838387834,-0.34271037257634035,1.1920373832406677,0.2949552633600194,-0.4368340474097858,0.25055651741635415,0.0033102074454991735,-0.5317815003956151,0.5362471404769038,1.1092852207351331,-0.13382247009957884,-0.08792739806811385,-0.156840189674286,-0.6035477250676271,-0.5317815003956151,-0.3193053506689896,2.750779178310562,-0.08792739806811385,-0.5317815003956151,0.27277669272882116,0.6658706672953714,0.07126469850274689,-0.13382247009957884,1.4169669380234817,0.31709249325645056,-0.13382247009957884,0.11634661657064145,-0.203017633379766,0.8789517589290488,-0.24938664580266173,-0.203017633379766,0.04865771165184635,0.7728635640285376,0.5579462590868453,0.8366233840884401,4.533482019529468,-0.1108516474371695,0.6658706672953714,-0.01943091003423015,0.3612439724526373,-0.9451070759599981,-0.08792739806811385,0.6443611882223067,-0.04221734363056225,0.11634661657064145 | 3,329 |
Contractures of the joints of the upper limbs | 14 | 79 | 2.192975 | 0.028309 | Q8IZA0,Q99720,O75844,Q9Y619,P37268,Q15392,P23786,Q9NR77,P42892,P07196,Q96AY3,Q9UJX6,O43909,P35637 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 162,194,131,39,7,12,77,15,82,306,21,290,185,127 | 2891,2697,2926,2551,1777,185,1779,843,525,2344,131,873,2656,593,306,1589,1233,2743,2986,77,1234,374,2604,619,127,7,620,82,2666,660,1366,528,822,2514,1854,3120,998,2430,2931,1739,2255,2526,1202,2256,2374,3066,1943,12,325,1550,3318,426,162,3269,2387,753,2439,2761,2320,21,2144,2145,3024,1449,194,2484,2765,1130,981,15,290,2815,474,1410,2281,3116,39,3117,2222 | -0.6999979046598092,-0.5795719264467128,-0.724249340547183,-0.5079660590613365,-0.203017633379766,1.47766044819358,-0.203017633379766,0.25055651741635415,0.5796069942263014,-0.41322685082973565,1.8165897720528055,0.22829447058781055,-0.5556499880877578,0.4927328204863091,0.9841607712980948,-0.13382247009957884,0.026006314080828572,-0.6035477250676271,-0.7729219653555064,2.546140982982583,0.026006314080828572,0.8366233840884401,-0.5317815003956151,0.4709171468581955,1.8755510915900018,5.721954661682018,0.4709171468581955,2.452198066890038,-0.5556499880877578,0.4271675731360321,-0.04221734363056225,0.5796069942263014,0.27277669272882116,-0.4842032649662147,-0.2261780242890793,-0.9203310164531874,0.16125438838387834,-0.4368340474097858,-0.724249340547183,-0.17990513363585875,-0.3661653856138045,-0.4842032649662147,0.04865771165184635,-0.3661653856138045,-0.41322685082973565,-0.8463621203281708,-0.24938664580266173,4.796997022347357,0.9421810860656006,-0.1108516474371695,-2.7770885112552186,0.7301764410183317,1.6581316076819692,-1.3760283681740184,-0.41322685082973565,0.3391886435203106,-0.4368340474097858,-0.6035477250676271,-0.38967075507457544,4.249159388964148,-0.3193053506689896,-0.3193053506689896,-0.7973440593945568,-0.06504940216522562,1.4372284667550546,-0.46049272408808617,-0.6035477250676271,0.09382756959687372,0.18364368033144304,4.533482019529468,1.0677113479047518,-0.6275777989300914,0.6658706672953714,-0.04221734363056225,-0.3661653856138045,-0.8956151662633678,3.52590265888114,-0.8956151662633678,-0.34271037257634035 | 3,329 |
Abnormal nerve conduction velocity | 10 | 46 | 2.179749 | 0.029276 | Q5TAQ9,Q99720,Q9Y619,O95831,Q9NR77,P07602,Q15120,O95140,Q7LG56,Q8N2K0 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 259,194,39,105,15,143,250,248,189,94 | 765,810,1779,1418,248,105,2656,3059,306,143,921,2954,769,2746,1115,492,2748,961,1852,1600,2361,2902,3121,1802,1285,2074,250,259,189,972,94,974,1955,3258,194,2210,2692,15,3051,866,2154,1176,2281,3116,39,2222 | 0.31709249325645056,0.27277669272882116,-0.203017633379766,-0.06504940216522562,1.1920373832406677,2.1089741942010813,-0.5556499880877578,-0.8463621203281708,0.9841607712980948,1.7573792946827045,0.2059902824751761,-0.7485572109498702,0.31709249325645056,-0.6035477250676271,0.09382756959687372,0.6228142321842982,-0.6035477250676271,0.18364368033144304,-0.2261780242890793,-0.13382247009957884,-0.41322685082973565,-0.6999979046598092,-0.9203310164531874,-0.203017633379766,0.0033102074454991735,-0.29594995909674393,1.1920373832406677,1.1713983468947904,1.457459585216246,0.18364368033144304,2.262511421655104,0.18364368033144304,-0.24938664580266173,-1.3243326104741977,1.4372284667550546,-0.34271037257634035,-0.5556499880877578,4.533482019529468,-0.82182395495969,0.25055651741635415,-0.3193053506689896,0.07126469850274689,-0.3661653856138045,-0.8956151662633678,3.52590265888114,-0.34271037257634035 | 3,329 |
Dwarfism | 7 | 53 | 2.169108 | 0.030075 | Q15125,Q32P28,O95831,Q96PZ0,O43909,Q14739,Q7RTS9 | Drugs and Diseases | Protein Atlas Disease involvement | protein_atlas_disease_involvement | 99,37,105,9,185,26,28 | 2223,575,2697,489,185,2860,2344,335,2226,452,105,2501,2782,1233,2954,2290,2232,2955,1794,1595,2606,2176,2179,660,2000,188,2299,999,1940,2871,2526,966,26,2374,99,1746,37,3123,325,2805,28,3045,857,2204,2144,1334,9,1251,503,1973,950,1832,1410 | -0.3661653856138045,0.5145094059098909,-0.5795719264467128,0.6228142321842982,1.47766044819358,-0.6758024598264976,-0.41322685082973565,0.9211394780417321,-0.3661653856138045,0.6873428903362069,2.1089741942010813,-0.4842032649662147,-0.6275777989300914,0.026006314080828572,-0.7485572109498702,-0.38967075507457544,-0.3661653856138045,-0.7485572109498702,-0.203017633379766,-0.13382247009957884,-0.5317815003956151,-0.34271037257634035,-0.34271037257634035,0.4271675731360321,-0.27264384148485665,1.457459585216246,-0.38967075507457544,0.16125438838387834,-0.24938664580266173,-0.6758024598264976,-0.4842032649662147,0.18364368033144304,3.908602733869772,-0.41322685082973565,2.2051248024821013,-0.17990513363585875,3.596143058067744,-0.9203310164531874,0.9421810860656006,-0.6275777989300914,3.874170839925339,-0.82182395495969,0.25055651741635415,-0.34271037257634035,-0.3193053506689896,-0.01943091003423015,5.185270547408719,0.026006314080828572,0.6228142321842982,-0.24938664580266173,0.2059902824751761,-0.203017633379766,-0.04221734363056225 | 3,329 |
Ragged red muscle fibers | 9 | 19 | 2.151447 | 0.031441 | Q9Y5P6,O75648,Q9H2D1,O95831,P12235,Q06210,P00846,Q70HW3,Q7LG56 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 332,410,69,105,266,323,24,27,189 | 459,410,105,3302,24,2821,266,1844,1853,323,2530,27,189,2198,2810,2265,69,3145,332 | 0.6658706672953714,0.7515381995844014,2.1089741942010813,-1.9922392137678377,4.04563696990221,-0.6516625684987778,1.1092852207351331,-0.2261780242890793,-0.2261780242890793,0.9421810860656006,-0.4842032649662147,3.908602733869772,1.457459585216246,-0.34271037257634035,-0.6275777989300914,-0.3661653856138045,2.7322889967086703,-0.9451070759599981,0.9421810860656006 | 3,329 |
Impaired proprioception | 10 | 46 | 2.140248 | 0.032335 | Q5TAQ9,Q9Y619,Q8IV08,Q9H6K4,Q9NR77,Q9NQ11,P41440,P00846,Q15120,O95140 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 259,39,269,206,15,275,55,24,250,248 | 914,842,2551,741,2045,1187,873,248,24,1923,306,3099,1474,921,1476,2508,2746,55,622,1854,2361,1802,1739,416,3254,2717,250,259,1881,269,535,3269,1296,2963,3298,2810,1394,736,206,275,15,3051,1459,39,1709,2222 | 0.2059902824751761,0.25055651741635415,-0.5079660590613365,0.3391886435203106,-0.29594995909674393,0.04865771165184635,0.22829447058781055,1.1920373832406677,4.04563696990221,-0.24938664580266173,0.9841607712980948,-0.8956151662633678,-0.08792739806811385,0.2059902824751761,-0.08792739806811385,-0.4842032649662147,-0.6035477250676271,3.0073424154788886,0.4709171468581955,-0.2261780242890793,-0.41322685082973565,-0.203017633379766,-0.17990513363585875,0.7515381995844014,-1.2985888439224271,-0.5795719264467128,1.1920373832406677,1.1713983468947904,-0.2261780242890793,1.1092852207351331,0.5796069942263014,-1.3760283681740184,0.0033102074454991735,-0.7485572109498702,-1.8546517595200398,-0.6275777989300914,-0.04221734363056225,0.3612439724526373,1.3763520238062164,1.0885149161930745,4.533482019529468,-0.82182395495969,-0.06504940216522562,3.52590265888114,-0.156840189674286,-0.34271037257634035 | 3,329 |
Dioxygenase activity | 6 | 23 | 2.132393 | 0.032975 | O00625,Q32P28,P13674,Q9H6W3,O15460,Q9NVH6 | Functions | GO Molecular function | msigdb_gomf | 36,37,201,153,247,126 | 2926,36,247,843,380,1232,201,1589,1739,1370,1442,37,3070,933,2805,1753,904,1253,3236,153,126,1979,3006 | -0.724249340547183,3.596143058067744,1.1920373832406677,0.25055651741635415,0.815405949185715,0.026006314080828572,1.396674842878999,-0.13382247009957884,-0.17990513363585875,-0.04221734363056225,-0.06504940216522562,3.596143058067744,-0.8463621203281708,0.2059902824751761,-0.6275777989300914,-0.17990513363585875,0.22829447058781055,0.026006314080828572,-1.1962933336355144,1.6979160391392325,1.8951501094270817,-0.24938664580266173,-0.7729219653555064 | 3,329 |
Antigen processing cross presentation | 9 | 54 | 2.128567 | 0.03329 | P28070,P25786,P10321,P20618,Q9UIQ6,Q03518,P28074,P49721,P28072 | Processes and pathways | Reactome Pathways | msigdb_reactome | 129,257,291,167,13,110,147,59,60 | 1572,761,3194,1573,2698,1918,561,1139,1781,508,614,615,1523,291,2505,167,257,1193,991,1656,2461,2661,129,60,147,3037,2417,2790,2608,996,59,1535,1735,1665,297,1438,1541,1603,2003,1542,110,2071,925,2524,2075,1122,1888,604,2322,408,13,1910,2108,3117 | -0.13382247009957884,0.31709249325645056,-1.0699083431145306,-0.13382247009957884,-0.5795719264467128,-0.24938664580266173,0.5362471404769038,0.07126469850274689,-0.203017633379766,0.6012295760038491,0.4709171468581955,0.4709171468581955,-0.1108516474371695,1.0468743338568534,-0.4842032649662147,1.5982387622118392,1.1713983468947904,0.04865771165184635,0.16125438838387834,-0.156840189674286,-0.46049272408808617,-0.5556499880877578,1.8362710532052997,2.897905946491273,1.7375864773292968,-0.82182395495969,-0.4368340474097858,-0.6275777989300914,-0.5317815003956151,0.16125438838387834,2.970948746307514,-0.1108516474371695,-0.17990513363585875,-0.156840189674286,1.0260036903302046,-0.06504940216522562,-0.1108516474371695,-0.13382247009957884,-0.27264384148485665,-0.1108516474371695,2.0509750105284508,-0.29594995909674393,0.2059902824751761,-0.4842032649662147,-0.29594995909674393,0.09382756959687372,-0.2261780242890793,0.4927328204863091,-0.38967075507457544,0.7728635640285376,4.780639478907166,-0.2261780242890793,-0.29594995909674393,-0.8956151662633678 | 3,329 |
Calcium ion transmembrane transport | 9 | 38 | 2.118484 | 0.034134 | P62942,P21796,P78417,P42858,Q00535,Q8WWC4,P16615,Q9HC07,Q06787 | Processes and pathways | GO Biological process | msigdb_gobp | 0,64,198,296,495,407,490,222,416 | 2949,1987,790,1784,2350,2706,563,1586,490,2863,1475,1076,64,1928,1526,922,296,1602,1541,1239,0,198,495,416,1149,2994,1951,937,1047,407,3164,1760,2727,222,1636,1637,1180,1513 | -0.7485572109498702,-0.27264384148485665,0.2949552633600194,-0.203017633379766,-0.41322685082973565,-0.5795719264467128,0.5362471404769038,-0.13382247009957884,0.6228142321842982,-0.6758024598264976,-0.08792739806811385,0.11634661657064145,2.824517962466285,-0.24938664580266173,-0.1108516474371695,0.2059902824751761,1.0260036903302046,-0.13382247009957884,-0.1108516474371695,0.026006314080828572,9.201100736968145,1.4169669380234817,0.6228142321842982,0.7515381995844014,0.07126469850274689,-0.7729219653555064,-0.24938664580266173,0.2059902824751761,0.1388221277863417,0.7728635640285376,-0.9948418387058783,-0.17990513363585875,-0.5795719264467128,1.2947503089070345,-0.13382247009957884,-0.13382247009957884,0.07126469850274689,-0.08792739806811385 | 3,329 |
Areflexia of lower limbs | 9 | 26 | 2.116743 | 0.034282 | Q15041,P12235,Q9H6K4,Q9NR77,Q15067,Q15120,O95140,Q7LG56,O60313 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 199,266,206,15,145,250,248,189,217 | 217,1109,1422,248,874,3059,306,266,2423,961,1854,2361,3121,2717,2572,199,145,250,1005,189,3298,2810,206,15,3051,1916 | 1.2947503089070345,0.09382756959687372,-0.06504940216522562,1.1920373832406677,0.22829447058781055,-0.8463621203281708,0.9841607712980948,1.1092852207351331,-0.4368340474097858,0.18364368033144304,-0.2261780242890793,-0.41322685082973565,-0.9203310164531874,-0.5795719264467128,-0.5079660590613365,1.4169669380234817,1.7573792946827045,1.1920373832406677,0.16125438838387834,1.457459585216246,-1.8546517595200398,-0.6275777989300914,1.3763520238062164,4.533482019529468,-0.82182395495969,-0.2261780242890793 | 3,329 |
Dioxygenase | 6 | 21 | 2.09987 | 0.03574 | O00625,Q32P28,P13674,Q9H6W3,O15460,Q9NVH6 | Functions | Protein Atlas Molecular function | protein_atlas_molecular_function | 36,37,201,153,247,126 | 2926,36,247,843,380,201,1739,1370,1442,37,3070,933,2805,1753,904,1253,3236,153,126,1979,3006 | -0.724249340547183,3.596143058067744,1.1920373832406677,0.25055651741635415,0.815405949185715,1.396674842878999,-0.17990513363585875,-0.04221734363056225,-0.06504940216522562,3.596143058067744,-0.8463621203281708,0.2059902824751761,-0.6275777989300914,-0.17990513363585875,0.22829447058781055,0.026006314080828572,-1.1962933336355144,1.6979160391392325,1.8951501094270817,-0.24938664580266173,-0.7729219653555064 | 3,329 |
Negative regulation of mrna metabolic process | 21 | 47 | 2.097563 | 0.035944 | Q5VTR2,Q13242,P11940,P16989,Q14103,Q06787,O60506,P61978,P98175,Q99729,Q13247,P67809,P22626,Q14011,Q16539,Q13148,P26368,Q07021,Q92804,P38159,P35637 | Processes and pathways | GO Biological process | msigdb_gobp | 774,513,639,271,405,416,278,414,298,317,686,314,202,203,731,730,594,729,103,236,127 | 2223,2038,1183,278,1071,2927,2598,875,639,271,2121,202,594,2123,127,236,414,314,298,1544,416,729,1860,1606,2305,730,1864,513,686,203,405,772,929,731,1548,774,1618,1948,1751,3209,1757,103,317,2586,1015,1634,1411 | -0.3661653856138045,-0.29594995909674393,0.04865771165184635,1.0677113479047518,0.11634661657064145,-0.724249340547183,-0.5317815003956151,0.22829447058781055,0.4490621451928765,1.0885149161930745,-0.3193053506689896,1.396674842878999,0.4927328204863091,-0.3193053506689896,1.8755510915900018,1.2332184926667917,0.7515381995844014,0.9631881196187747,1.0260036903302046,-0.1108516474371695,0.7515381995844014,0.3612439724526373,-0.2261780242890793,-0.13382247009957884,-0.38967075507457544,0.3612439724526373,-0.2261780242890793,0.6012295760038491,0.40523318577404505,1.396674842878999,0.7728635640285376,0.31709249325645056,0.2059902824751761,0.3612439724526373,-0.1108516474371695,0.31709249325645056,-0.13382247009957884,-0.24938664580266173,-0.17990513363585875,-1.0950564604153394,-0.17990513363585875,2.1282554740320596,0.9631881196187747,-0.5079660590613365,0.16125438838387834,-0.13382247009957884,-0.04221734363056225 | 3,329 |
Cdt1 association with the cdc6 orc origin complex | 7 | 40 | 2.091446 | 0.036488 | P28070,P25786,Q9Y619,P20618,P28074,P49721,P28072 | Processes and pathways | Reactome Pathways | msigdb_reactome | 129,257,39,167,147,59,60 | 761,3194,1573,2698,1139,789,508,2505,167,257,1193,991,1656,2661,129,60,147,2417,2790,2608,996,59,1535,1735,297,1438,1603,2003,1542,2071,2524,2075,1122,1888,604,2322,2978,1910,2108,39 | 0.31709249325645056,-1.0699083431145306,-0.13382247009957884,-0.5795719264467128,0.07126469850274689,0.2949552633600194,0.6012295760038491,-0.4842032649662147,1.5982387622118392,1.1713983468947904,0.04865771165184635,0.16125438838387834,-0.156840189674286,-0.5556499880877578,1.8362710532052997,2.897905946491273,1.7375864773292968,-0.4368340474097858,-0.6275777989300914,-0.5317815003956151,0.16125438838387834,2.970948746307514,-0.1108516474371695,-0.17990513363585875,1.0260036903302046,-0.06504940216522562,-0.13382247009957884,-0.27264384148485665,-0.1108516474371695,-0.29594995909674393,-0.4842032649662147,-0.29594995909674393,0.09382756959687372,-0.2261780242890793,0.4927328204863091,-0.38967075507457544,-0.7485572109498702,-0.2261780242890793,-0.29594995909674393,3.52590265888114 | 3,329 |
Neuron apoptotic process | 18 | 49 | 2.089399 | 0.036672 | P50897,Q15058,Q99720,Q969N2,Q9NR28,P51858,O95831,Q01105,O95630,P07196,P09601,O76024,Q00535,P49327,Q04446,P42574,Q96A26,P04062 | Processes and pathways | GO Biological process | msigdb_gobp | 128,688,194,778,101,643,105,268,576,306,53,744,495,342,665,527,125,191 | 1188,744,576,105,191,2703,1840,2411,1923,306,1469,53,2601,1586,2059,527,1729,1435,2062,1533,342,2748,128,2514,643,1937,2183,1540,963,495,268,665,1149,1281,1609,1675,1442,688,1242,802,778,125,1011,2847,194,1058,101,953,3054 | 0.04865771165184635,0.3391886435203106,0.5145094059098909,2.1089741942010813,1.4372284667550546,-0.5795719264467128,-0.2261780242890793,-0.4368340474097858,-0.24938664580266173,0.9841607712980948,-0.08792739806811385,3.025507611654335,-0.5317815003956151,-0.13382247009957884,-0.29594995909674393,0.5796069942263014,-0.17990513363585875,-0.06504940216522562,-0.29594995909674393,-0.1108516474371695,0.900063101102262,-0.6035477250676271,1.8755510915900018,-0.4842032649662147,0.4490621451928765,-0.24938664580266173,-0.34271037257634035,-0.1108516474371695,0.18364368033144304,0.6228142321842982,1.1092852207351331,0.4271675731360321,0.07126469850274689,0.0033102074454991735,-0.13382247009957884,-0.156840189674286,-0.06504940216522562,0.40523318577404505,0.026006314080828572,0.2949552633600194,0.31709249325645056,1.8951501094270817,0.16125438838387834,-0.6516625684987778,1.4372284667550546,0.1388221277863417,2.147511059051131,0.2059902824751761,-0.82182395495969 | 3,329 |
Cellular monovalent inorganic cation homeostasis | 6 | 26 | 2.086185 | 0.036962 | P50897,Q8N511,Q93050,Q9Y487,O75503,Q9HC07 | Processes and pathways | GO Biological process | msigdb_gobp | 128,327,164,149,54,222 | 54,1422,845,1784,2228,616,3086,374,128,1852,661,2246,727,1280,1747,327,833,164,804,1893,222,1345,1134,1909,149,2164 | 3.0073424154788886,-0.06504940216522562,0.25055651741635415,-0.203017633379766,-0.3661653856138045,0.4709171468581955,-0.8709590302873479,0.8366233840884401,1.8755510915900018,-0.2261780242890793,0.4271675731360321,-0.3661653856138045,0.3612439724526373,0.0033102074454991735,-0.17990513363585875,0.9421810860656006,0.27277669272882116,1.6182320603396134,0.2949552633600194,-0.2261780242890793,1.2947503089070345,-0.01943091003423015,0.09382756959687372,-0.2261780242890793,1.7177654379588205,-0.3193053506689896 | 3,329 |
protein modifying enzyme | 9 | 28 | 2.082895 | 0.037261 | P50897,Q92791,Q86YN1,P13674,Q9UMR5,O75718,O60725,O60476,O15460 | Functions | Panther Protein class | panther_protein_class | 128,169,264,201,176,335,56,372,247 | 2926,1184,1713,247,372,843,1420,56,335,201,681,128,1437,2519,1739,1370,1443,3292,3070,441,670,264,2140,169,978,1504,176,986 | -0.724249340547183,0.04865771165184635,-0.17990513363585875,1.1920373832406677,0.8366233840884401,0.25055651741635415,-0.06504940216522562,2.9891561548194527,0.9211394780417321,1.396674842878999,0.40523318577404505,1.8755510915900018,-0.06504940216522562,-0.4842032649662147,-0.17990513363585875,-0.04221734363056225,-0.06504940216522562,-1.7461022287373404,-0.8463621203281708,0.7087780760645422,0.4271675731360321,1.1300224418606861,-0.3193053506689896,1.5982387622118392,0.18364368033144304,-0.08792739806811385,1.55816439445645,0.18364368033144304 | 3,329 |
Golgi membrane | 47 | 142 | 2.080488 | 0.037481 | Q86Y82,Q16739,Q92614,O95197,Q9BXS4,Q15392,Q8IV08,Q8NCH0,O43731,P11717,Q96S66,P15291,P24390,Q14108,Q8IZA0,P51790,P10321,Q9BUR5,O43505,Q7LGA3,P26572,O43752,O95721,Q8NBN3,Q9H4A6,Q8N4V1,Q9BVK6,Q12907,Q9UBF8,Q9H7Z7,P49257,Q9HC07,P35613,Q96JB2,Q9Y282,O95070,Q7Z3C6,O15027,Q9P2W9,P78536,Q16799,O00461,Q15363,P0CG08,P04439,P01889,O60476 | Localization | GO Cellular component | msigdb_gocc | 517,258,262,135,139,12,269,146,19,657,284,526,30,156,162,661,291,556,171,426,681,184,312,63,589,715,329,710,473,606,220,222,218,252,97,592,600,350,233,479,102,111,115,616,615,614,372 | 1772,111,1068,2166,350,1355,788,171,19,2285,184,372,1421,1781,592,135,312,2499,614,615,3012,616,291,657,526,1430,1431,30,681,959,218,1433,818,1195,2179,820,220,793,961,1599,2181,661,997,2958,2613,2563,851,1937,3062,1538,2130,1277,1034,2615,2365,479,1119,2616,1674,887,1441,709,1369,1037,888,710,1609,156,2258,967,3039,2574,115,2135,12,1087,2801,258,102,1045,426,600,2532,1812,517,1949,1294,269,162,715,1684,63,146,1159,1816,1160,2202,938,262,939,2320,3023,252,2144,284,1893,556,329,2588,139,1053,1825,2024,905,589,606,2813,779,3179,222,1132,1630,1704,1133,1831,1347,233,2217,473,1134,1768,2159,1637,97,1222,1021,2219,2644,2033,1770,1570,2856 | -0.203017633379766,2.031589771535772,0.11634661657064145,-0.34271037257634035,0.8789517589290488,-0.04221734363056225,0.2949552633600194,1.578216255499028,4.266012245132118,-0.38967075507457544,1.47766044819358,0.8366233840884401,-0.06504940216522562,-0.203017633379766,0.4927328204863091,1.7968808074173586,0.9631881196187747,-0.4842032649662147,0.4709171468581955,0.4709171468581955,-0.7973440593945568,0.4709171468581955,1.0468743338568534,0.4271675731360321,0.5796069942263014,-0.06504940216522562,-0.06504940216522562,3.8223910414490736,0.40523318577404505,0.18364368033144304,1.2947503089070345,-0.06504940216522562,0.27277669272882116,0.04865771165184635,-0.34271037257634035,0.27277669272882116,1.2947503089070345,0.2949552633600194,0.18364368033144304,-0.13382247009957884,-0.34271037257634035,0.4271675731360321,0.16125438838387834,-0.7485572109498702,-0.5317815003956151,-0.5079660590613365,0.25055651741635415,-0.24938664580266173,-0.8463621203281708,-0.1108516474371695,-0.3193053506689896,0.0033102074454991735,0.1388221277863417,-0.5317815003956151,-0.41322685082973565,0.6443611882223067,0.09382756959687372,-0.5317815003956151,-0.156840189674286,0.22829447058781055,-0.06504940216522562,0.3832587355956147,-0.04221734363056225,0.1388221277863417,0.22829447058781055,0.3832587355956147,-0.13382247009957884,1.678038142292685,-0.3661653856138045,0.18364368033144304,-0.82182395495969,-0.5079660590613365,1.9732758301648015,-0.3193053506689896,4.796997022347357,0.11634661657064145,-0.6275777989300914,1.1713983468947904,2.1282554740320596,0.1388221277863417,0.7301764410183317,0.4927328204863091,-0.4842032649662147,-0.203017633379766,0.6012295760038491,-0.24938664580266173,0.0033102074454991735,1.1092852207351331,1.6581316076819692,0.3832587355956147,-0.156840189674286,2.842897623965077,1.7573792946827045,0.07126469850274689,-0.203017633379766,0.07126469850274689,-0.34271037257634035,0.2059902824751761,1.1507267582378766,0.2059902824751761,-0.38967075507457544,-0.7973440593945568,1.1920373832406677,-0.3193053506689896,1.0677113479047518,-0.2261780242890793,0.5579462590868453,0.9421810860656006,-0.5079660590613365,1.7968808074173586,0.1388221277863417,-0.203017633379766,-0.27264384148485665,0.22829447058781055,0.5145094059098909,0.4927328204863091,-0.6275777989300914,0.31709249325645056,-1.0198015679513603,1.2947503089070345,0.09382756959687372,-0.13382247009957884,-0.156840189674286,0.09382756959687372,-0.203017633379766,-0.01943091003423015,1.253760908657221,-0.34271037257634035,0.6658706672953714,0.09382756959687372,-0.17990513363585875,-0.3193053506689896,-0.13382247009957884,2.243407596862186,0.04865771165184635,0.16125438838387834,-0.34271037257634035,-0.5317815003956151,-0.27264384148485665,-0.17990513363585875,-0.1108516474371695,-0.6516625684987778 | 3,329 |
Abnormal femoral neck morphology | 10 | 39 | 2.077765 | 0.037731 | O75844,Q9Y619,O95613,O95831,O75718,Q96AY3,Q9Y487,O43909,P28482,Q7RTS9 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 131,39,452,105,335,21,149,185,374,28 | 2697,1067,185,2860,988,335,131,452,105,2656,791,2557,2743,2232,374,995,2666,2179,822,1437,727,3017,2374,2755,3068,28,626,21,2204,2144,503,779,1973,950,1410,2032,149,1708,39 | -0.5795719264467128,0.11634661657064145,1.47766044819358,-0.6758024598264976,0.16125438838387834,0.9211394780417321,1.8165897720528055,0.6873428903362069,2.1089741942010813,-0.5556499880877578,0.2949552633600194,-0.5079660590613365,-0.6035477250676271,-0.3661653856138045,0.8366233840884401,0.16125438838387834,-0.5556499880877578,-0.34271037257634035,0.27277669272882116,-0.06504940216522562,0.3612439724526373,-0.7973440593945568,-0.41322685082973565,-0.6035477250676271,-0.8463621203281708,3.874170839925339,0.4709171468581955,4.249159388964148,-0.34271037257634035,-0.3193053506689896,0.6228142321842982,0.31709249325645056,-0.24938664580266173,0.2059902824751761,-0.04221734363056225,-0.27264384148485665,1.7177654379588205,-0.156840189674286,3.52590265888114 | 3,329 |
Envelope | 122 | 495 | 2.075471 | 0.037943 | Q8N183,Q96ER9,Q9NS69,Q9Y6N1,Q5BJF2,Q96AY3,Q8N0X7,Q9NQ50,P00846,Q14739,Q70HW3,Q7Z7H8,Q567V2,P50402,O00264,Q99595,Q9HB71,Q9Y619,Q9BUR5,Q7Z7F7,O43772,P80303,Q69YU5,Q9NVS2,Q8N4Q1,P09601,P14406,P57088,P0DP25,O43169,P82912,P21796,Q9HD42,Q9BSK2,P45880,Q9H4A6,Q9H2D1,Q96NB2,Q8IUX1,Q6NUK1,P57105,P23786,Q9NZZ3,Q8N4H5,O95563,Q13084,O94901,Q15125,Q9NRA0,Q9NR28,Q96KC8,O95831,O75964,Q02978,O15173,Q96A26,P53701,Q9Y2R0,O75844,Q99523,Q96CU9,Q5T653,O14949,O95373,O43676,Q9UDW1,Q6DKK2,Q99720,Q15070,P30536,Q9UDX5,O60313,Q9UBM7,O75306,O14925,Q9BTX1,O95140,O95674,Q9H061,P12235,Q9NPL8,P34897,Q96S66,Q15007,Q9BUK6,P67809,O75880,Q9H1E5,Q8NI60,P82675,P62995,Q9BYT8,Q9NQZ5,Q5XKP0,P20674,Q8N983,Q6P4A7,Q9H3K2,Q86Y39,Q9Y6C9,Q9UBX3,Q9P035,O15118,O15397,O75438,O95168,Q16134,Q8WWC4,Q9H4L5,Q9BXK5,Q99543,Q9Y6M9,Q9UBF8,Q9NX63,Q96TA2,P52789,Q9Y512,Q9BRJ2,Q7KZN9,P82933,Q9H8M7,O15228 | Localization | GO Cellular component | msigdb_gocc | 518,539,16,546,18,21,535,541,24,26,27,533,29,528,524,35,559,39,556,42,44,46,48,574,50,53,57,565,563,62,566,64,590,66,67,589,69,587,586,585,579,77,609,92,93,595,591,99,631,101,628,105,104,106,114,125,132,134,131,138,142,157,154,160,163,175,186,194,200,212,223,217,240,234,241,245,248,255,260,266,274,272,284,280,294,314,311,330,328,322,321,345,358,355,351,369,376,379,377,390,398,397,400,402,403,404,406,407,429,458,457,475,473,472,467,464,488,487,483,480,505,489 | 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| 3,329 |
Diminished movement | 6 | 20 | 2.072331 | 0.038235 | P42858,O95831,P12235,Q9NQ11,Q7LG56,P04062 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 296,105,266,275,189,191 | 105,191,593,266,2953,296,313,2069,1742,1744,500,189,1301,1692,2810,1449,275,1767,1917,913 | 2.1089741942010813,1.4372284667550546,0.4927328204863091,1.1092852207351331,-0.7485572109498702,1.0260036903302046,0.9631881196187747,-0.29594995909674393,-0.17990513363585875,-0.17990513363585875,0.6228142321842982,1.457459585216246,0.0033102074454991735,-0.156840189674286,-0.6275777989300914,-0.06504940216522562,1.0885149161930745,-0.17990513363585875,-0.2261780242890793,0.22829447058781055 | 3,329 |
Metal ion homeostasis | 19 | 77 | 2.065733 | 0.038854 | P62942,P30519,Q9HD20,Q9NQ11,Q9Y6N1,Q9Y487,Q8WWC4,P42858,O15164,Q9Y5X3,P09601,O75880,Q8N511,P78417,Q9HC07,Q9Y639,P02786,Q00535,P16615 | Processes and pathways | GO Biological process | msigdb_gobp | 0,11,140,275,546,149,407,296,548,449,53,311,327,198,222,95,477,495,490 | 2924,2166,548,2045,2949,743,2652,311,2819,744,790,3131,477,2703,3148,845,1784,2822,2706,1523,53,563,1472,1360,490,2863,1475,1076,3297,1928,2461,1526,11,922,2239,296,2181,2467,2246,727,1239,0,198,495,1149,926,2718,1871,2574,1747,773,1951,937,327,1683,2582,1047,2842,2583,407,626,1760,2727,2099,1254,2102,222,140,275,1636,1637,677,149,1513,449,95,546 | -0.724249340547183,-0.34271037257634035,0.5579462590868453,-0.29594995909674393,-0.7485572109498702,0.3391886435203106,-0.5556499880877578,0.9631881196187747,-0.6516625684987778,0.3391886435203106,0.2949552633600194,-0.9451070759599981,0.6443611882223067,-0.5795719264467128,-0.9699438469321776,0.25055651741635415,-0.203017633379766,-0.6516625684987778,-0.5795719264467128,-0.1108516474371695,3.025507611654335,0.5362471404769038,-0.08792739806811385,-0.04221734363056225,0.6228142321842982,-0.6758024598264976,-0.08792739806811385,0.11634661657064145,-1.8546517595200398,-0.24938664580266173,-0.46049272408808617,-0.1108516474371695,4.959771689307768,0.2059902824751761,-0.3661653856138045,1.0260036903302046,-0.34271037257634035,-0.46049272408808617,-0.3661653856138045,0.3612439724526373,0.026006314080828572,9.201100736968145,1.4169669380234817,0.6228142321842982,0.07126469850274689,0.2059902824751761,-0.5795719264467128,-0.2261780242890793,-0.5079660590613365,-0.17990513363585875,0.31709249325645056,-0.24938664580266173,0.2059902824751761,0.9421810860656006,-0.156840189674286,-0.5079660590613365,0.1388221277863417,-0.6516625684987778,-0.5079660590613365,0.7728635640285376,0.4709171468581955,-0.17990513363585875,-0.5795719264467128,-0.29594995909674393,0.026006314080828572,-0.29594995909674393,1.2947503089070345,1.7968808074173586,1.0885149161930745,-0.13382247009957884,-0.13382247009957884,0.4271675731360321,1.7177654379588205,-0.08792739806811385,0.7087780760645422,2.262511421655104,0.5796069942263014 | 3,329 |
Abnormality of peripheral nerves | 12 | 51 | 2.062204 | 0.039188 | Q5TAQ9,Q99720,Q9Y619,O95831,Q9NR77,P07602,P07196,O15270,Q15120,O95140,Q7LG56,Q8N2K0 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 259,194,39,105,15,143,306,216,250,248,189,94 | 765,216,810,1779,1418,248,312,105,2656,3059,306,143,921,2954,769,2746,1115,492,2748,961,1852,1600,2361,2902,3121,1802,1285,2074,250,259,1617,189,972,94,974,1955,444,3298,3258,194,2210,2692,15,3051,866,2154,1176,2281,3116,39,2222 | 0.31709249325645056,1.2947503089070345,0.27277669272882116,-0.203017633379766,-0.06504940216522562,1.1920373832406677,0.9631881196187747,2.1089741942010813,-0.5556499880877578,-0.8463621203281708,0.9841607712980948,1.7573792946827045,0.2059902824751761,-0.7485572109498702,0.31709249325645056,-0.6035477250676271,0.09382756959687372,0.6228142321842982,-0.6035477250676271,0.18364368033144304,-0.2261780242890793,-0.13382247009957884,-0.41322685082973565,-0.6999979046598092,-0.9203310164531874,-0.203017633379766,0.0033102074454991735,-0.29594995909674393,1.1920373832406677,1.1713983468947904,-0.13382247009957884,1.457459585216246,0.18364368033144304,2.262511421655104,0.18364368033144304,-0.24938664580266173,0.7087780760645422,-1.8546517595200398,-1.3243326104741977,1.4372284667550546,-0.34271037257634035,-0.5556499880877578,4.533482019529468,-0.82182395495969,0.25055651741635415,-0.3193053506689896,0.07126469850274689,-0.3661653856138045,-0.8956151662633678,3.52590265888114,-0.34271037257634035 | 3,329 |
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